Doomsday + Wheel of Fortune + Laboratory Maniac

Doomsday
Wheel of Fortune
Laboratory Maniac

Requires
Laboratory Maniac on the battlefield. All other cards in hand. 2bbbr available.
Steps
  1. Cast Doomsday by paying bbb, searching your library and graveyard for any five other cards, exiling all other cards from your graveyard and library, and then placing the remaining cards on top of your library and losing half your life, rounded up
  2. Cast Wheel of Fortune by paying 2r, causing each player to discard their hand, and causing you to win the game due to drawing from an empty library
Results
Win the game.