Beacon of Immortality + Plague Drone

Beacon of Immortality
Plague Drone

Requires
Beacon of Immortality in hand. Plague Drone on the battlefield. 5w available.
Steps
  1. Cast Beacon of Immortality by paying 5w, causing target opponent to lose life equal to their life total due to Plague Drone
  2. The opponent loses the game due to having zero life
Results
Target opponent loses the game. Infinite lifeloss for target opponent.