Vilis, Broker of Blood + Curse of Fool's Wisdom + Vizkopa Guildmage

Vilis, Broker of Blood
Curse of Fool's Wisdom
Vizkopa Guildmage

Requires
Vilis, Broker of Blood must be on the battlefield. Curse of Fool's Wisdom must be on the battlefield. Vizkopa Guildmage must be on the battlefield. Curse of Fool's Wisdom attached to you. The number of cards in your library is at least equal to the highest life total among opponents. Your life total is at least 3. Mana needed: 1
Steps
  1. Activate Vizkopa Guildmage's second ability by paying 1, creating a triggered ability that will cause opponents to lose life each time you gain life this turn.
  2. Activate Vilis by paying and 2 life, targeting any creature.
  3. Vilis triggers, causing you to draw two cards.
  4. Curse of Fool's Wisdom triggers twice.
  5. Resolve one Curse of Fool's Wisdom trigger, losing 2 life and gaining 2 life.
  6. Vilis and Vizkopa Guildmage's ability trigger.
  7. Resolve the Vizkopa Guildmage's ability's trigger, causing each opponent to lose 2 life.
  8. Resolve the Vilis trigger, drawing two cards.
  9. Repeat from step 4.
Results
Infinite card draw. Infinite draw triggers. Infinite lifegain triggers. Near-infinite damage. Near-infinite lifegain. Near-infinite lifeloss.

Liesa, Shroud of Dusk
0.05% of 9374 decks 5 decks
Kambal, Consul of Allocation
0.14% of 2162 decks 3 decks
Queza, Augur of Agonies
0.05% of 6366 decks 3 decks
Teysa Karlov
0.01% of 15216 decks 1 decks
Ayli, Eternal Pilgrim
0.09% of 1124 decks 1 decks
Bjorna, Nightfall Alchemist // Wernog, Rider's Chaplain
0.03% of 2984 decks 1 decks
Oloro, Ageless Ascetic
0.01% of 12127 decks 1 decks
Kaalia of the Vast
0.00% of 20195 decks 1 decks
High Synergy Cards
Drogskol Reaver
80% of 5 decks +78% synergy
Vito, Thorn of the Dusk Rose
80% of 15 decks +75% synergy
Well of Lost Dreams
75% of 16 decks +73% synergy
Exquisite Blood
75% of 16 decks +70% synergy
Propaganda
80% of 5 decks +68% synergy
Sanguine Bond
69% of 16 decks +63% synergy
Marauding Blight-Priest
60% of 15 decks +57% synergy
Cliffhaven Vampire
50% of 16 decks +48% synergy
Smothering Tithe
69% of 16 decks +44% synergy
Blind Obedience
50% of 16 decks +43% synergy
Top Cards
Counterspell
80% of 5 decks +37% synergy
Swords to Plowshares
75% of 16 decks +12% synergy
Bolas's Citadel
50% of 16 decks +41% synergy
Ghostly Prison
50% of 16 decks +38% synergy
Path to Exile
50% of 16 decks +5% synergy
Dawn of Hope
44% of 16 decks +42% synergy
Authority of the Consuls
44% of 16 decks +40% synergy
Kambal, Consul of Allocation
44% of 16 decks +38% synergy
Peer into the Abyss
40% of 15 decks +37% synergy
Sheoldred, the Apocalypse
38% of 13 decks +33% synergy
Creatures
Faerie Mastermind
75% of 4 decks +68% synergy
Amalia Benavides Aguirre
50% of 6 decks +47% synergy
Crested Sunmare
38% of 16 decks +36% synergy
Karlov of the Ghost Council
38% of 16 decks +36% synergy
Soul's Attendant
38% of 16 decks +34% synergy
Lotho, Corrupt Shirriff
33% of 12 decks +19% synergy
Esper Sentinel
33% of 15 decks +13% synergy
Serra Ascendant
31% of 16 decks +27% synergy
Soul Warden
31% of 16 decks +26% synergy
Elas il-Kor, Sadistic Pilgrim
31% of 13 decks +19% synergy
Indulging Patrician
27% of 15 decks +25% synergy
Defiant Bloodlord
25% of 16 decks +24% synergy
Drana's Emissary
25% of 16 decks +23% synergy
Psychosis Crawler
25% of 16 decks +22% synergy
Suture Priest
25% of 16 decks +22% synergy
Gray Merchant of Asphodel
25% of 16 decks +16% synergy
Orcish Bowmasters
25% of 12 decks +14% synergy
Solemn Simulacrum
25% of 16 decks +11% synergy
Celestine, the Living Saint
23% of 13 decks +21% synergy
Rug of Smothering
20% of 15 decks +20% synergy
Keen Duelist
20% of 15 decks +19% synergy
Angel of Destiny
20% of 15 decks +18% synergy
Astarion, the Decadent
20% of 15 decks +18% synergy
Children of Korlis
19% of 16 decks +18% synergy
Epicure of Blood
19% of 16 decks +18% synergy
Pontiff of Blight
19% of 16 decks +18% synergy
Teysa, Envoy of Ghosts
19% of 16 decks +17% synergy
Archangel of Thune
19% of 16 decks +16% synergy
Twilight Prophet
19% of 16 decks +16% synergy
Crypt Ghast
19% of 16 decks +14% synergy
Instants
Dark Ritual
38% of 16 decks +15% synergy
Anguished Unmaking
38% of 16 decks +13% synergy
Teferi's Protection
31% of 16 decks +11% synergy
Angel's Grace
25% of 16 decks +23% synergy
Heliod's Intervention
25% of 16 decks +22% synergy
Generous Gift
25% of 16 decks -1% synergy
Beacon of Immortality
19% of 16 decks +18% synergy
Mortify
19% of 16 decks +7% synergy
Despark
19% of 16 decks +3% synergy
Sorceries
Windfall
60% of 5 decks +47% synergy
Exsanguinate
38% of 16 decks +32% synergy
Sign in Blood
38% of 16 decks +28% synergy
Farewell
33% of 15 decks +20% synergy
Debt to the Deathless
31% of 16 decks +28% synergy
Fumigate
25% of 16 decks +22% synergy
Night's Whisper
25% of 16 decks +16% synergy
Austere Command
25% of 16 decks +12% synergy
Demonic Tutor
25% of 16 decks +3% synergy
Revival // Revenge
19% of 16 decks +17% synergy
Ambition's Cost
19% of 16 decks +17% synergy
Kaya's Wrath
19% of 16 decks +16% synergy
Grim Tutor
19% of 16 decks +14% synergy
Diabolic Tutor
19% of 16 decks +12% synergy
Utility Artifacts
Aetherflux Reservoir
31% of 16 decks +27% synergy
Alhammarret's Archive
25% of 16 decks +23% synergy
Tainted Sigil
19% of 16 decks +18% synergy
Enchantments
Teferi's Ageless Insight
60% of 5 decks +55% synergy
Rhystic Study
60% of 5 decks +32% synergy
Phyrexian Arena
38% of 16 decks +23% synergy
Black Market Connections
33% of 15 decks +22% synergy
Tainted Remedy
31% of 16 decks +31% synergy
Bloodchief Ascension
31% of 16 decks +28% synergy
Necropotence
25% of 16 decks +20% synergy
Angelic Accord
19% of 16 decks +17% synergy
Luminarch Ascension
19% of 16 decks +17% synergy
Greed
19% of 16 decks +16% synergy
Planeswalkers
Sorin, Vengeful Bloodlord
38% of 16 decks +35% synergy
Ajani, Strength of the Pride
19% of 16 decks +17% synergy
Utility Lands
Reliquary Tower
50% of 16 decks +21% synergy
Temple of the False God
38% of 16 decks +28% synergy
Bojuka Bog
38% of 16 decks +7% synergy
Urborg, Tomb of Yawgmoth
31% of 16 decks +21% synergy
Eiganjo, Seat of the Empire
27% of 15 decks +18% synergy
Takenuma, Abandoned Mire
20% of 15 decks +9% synergy
Mistveil Plains
19% of 16 decks +17% synergy
Castle Locthwain
19% of 16 decks +13% synergy
Hall of Heliod's Generosity
19% of 16 decks +12% synergy
Ancient Tomb
19% of 16 decks +8% synergy
Vault of the Archangel
19% of 16 decks +8% synergy
Mana Artifacts
Sol Ring
88% of 16 decks +3% synergy
Arcane Signet
81% of 16 decks +9% synergy
Commander's Sphere
25% of 16 decks +10% synergy
Thought Vessel
25% of 16 decks +8% synergy
Talisman of Hierarchy
25% of 16 decks +0% synergy
Orzhov Signet
25% of 16 decks -2% synergy
Mind Stone
19% of 16 decks +1% synergy
Lands
Command Tower
88% of 16 decks +14% synergy
Sunken Hollow
80% of 5 decks +45% synergy
Caves of Koilos
62% of 16 decks +34% synergy
Arcane Sanctum
60% of 5 decks +32% synergy
Prairie Stream
60% of 5 decks +26% synergy
Fetid Heath
50% of 16 decks +39% synergy
Isolated Chapel
50% of 16 decks +23% synergy
Godless Shrine
50% of 16 decks +9% synergy
Temple of Silence
44% of 16 decks +26% synergy
Brightclimb Pathway
40% of 15 decks +30% synergy
Vault of Champions
40% of 15 decks +14% synergy
Marsh Flats
38% of 16 decks +26% synergy
Silent Clearing
31% of 16 decks +27% synergy
Orzhov Basilica
31% of 16 decks +15% synergy
Myriad Landscape
31% of 16 decks +12% synergy
Shineshadow Snarl
27% of 15 decks +14% synergy
Shattered Sanctum
27% of 15 decks +13% synergy
Concealed Courtyard
25% of 16 decks +19% synergy
Scoured Barrens
25% of 16 decks +16% synergy
Fabled Passage
25% of 16 decks +16% synergy
Tainted Field
25% of 16 decks +12% synergy
Opal Palace
19% of 16 decks +16% synergy
Terramorphic Expanse
19% of 16 decks +3% synergy
Exotic Orchard
19% of 16 decks -17% synergy