Worldfire + Hive Mind + Vampiric Tutor + Tidal Barracuda

Worldfire
Hive Mind
Vampiric Tutor
Tidal Barracuda

Requires
Worldfire must be in hand. Hive Mind must be on the battlefield. Vampiric Tutor must be in hand. Tidal Barracuda must be on the battlefield. Mana needed: 6
Steps
  1. Cast Vampiric Tutor by paying .
  2. Hive Mind triggers, causing each opponent to create a copy of Vampiric Tutor.
  3. Holding priority, cast Worldfire by paying 6.
  4. Hive Mind triggers, causing each opponent to create a copy of Worldfire.
  5. Resolve each Worldfire on the stack, exiling all permanents, all cards in all hands and graveyards, and setting each player's life total to one.
  6. Resolve the first opponent's copy of Vampiric Tutor, causing them to search their library for a card, put it on top of their library and lose 2 life.
  7. The opponent loses the game due to having less than zero life.
  8. Repeat from step 6 for each remaining opponent.
Results
Each opponent loses the game. Exile all cards in all hands and graveyards. Exile all permanents. Near-infinite lifeloss.

Nekusar, the Mindrazer
0.01% of 20392 decks 2 decks
Jodah, Archmage Eternal
0.01% of 8047 decks 1 decks
Game Changers
Vorinclex, Voice of Hunger
100% of 1 decks +98% synergy
Opposition Agent
67% of 3 decks +60% synergy
Thassa's Oracle
67% of 3 decks +60% synergy
Underworld Breach
33% of 3 decks +27% synergy
Ancient Tomb
33% of 3 decks +23% synergy
Fierce Guardianship
33% of 3 decks +15% synergy
Creatures
Disciple of Caelus Nin
100% of 1 decks +100% synergy
Fate Unraveler
100% of 3 decks +98% synergy
Suture Priest
100% of 1 decks +97% synergy
Nyxbloom Ancient
100% of 1 decks +96% synergy
Bloom Tender
100% of 1 decks +92% synergy
Faeburrow Elder
100% of 1 decks +89% synergy
Birds of Paradise
100% of 1 decks +73% synergy
Kami of the Crescent Moon
67% of 3 decks +65% synergy
Magus of the Wheel
67% of 3 decks +63% synergy
Sheoldred, the Apocalypse
67% of 3 decks +61% synergy
Death Cultist
33% of 3 decks +33% synergy
Phage the Untouchable
33% of 3 decks +33% synergy
Umbris, Fear Manifest
33% of 3 decks +33% synergy
Nekusar, the Mindrazer
33% of 3 decks +32% synergy
Bone Miser
33% of 3 decks +32% synergy
Glint-Horn Buccaneer
33% of 3 decks +31% synergy
Jace's Archivist
33% of 3 decks +31% synergy
Ojer Axonil, Deepest Might
33% of 3 decks +31% synergy
K'rrik, Son of Yawgmoth
33% of 3 decks +31% synergy
Deadeye Navigator
33% of 3 decks +31% synergy
Ertai Resurrected
33% of 3 decks +31% synergy
Psychosis Crawler
33% of 3 decks +31% synergy
Bloodletter of Aclazotz
33% of 3 decks +29% synergy
Laboratory Maniac
33% of 3 decks +29% synergy
Veyran, Voice of Duality
33% of 3 decks +29% synergy
Spark Double
33% of 3 decks +27% synergy
Roaming Throne
33% of 3 decks +26% synergy
Syr Konrad, the Grim
33% of 3 decks +24% synergy
Goblin Electromancer
33% of 3 decks +24% synergy
Orcish Bowmasters
33% of 3 decks +24% synergy
Instants
Pure Intentions
100% of 1 decks +100% synergy
Intervention Pact
100% of 1 decks +100% synergy
Summoner's Pact
100% of 1 decks +99% synergy
Teferi's Protection
100% of 1 decks +81% synergy
Pact of Negation
67% of 3 decks +59% synergy
Arcane Denial
67% of 3 decks +47% synergy
Pact of the Titan
33% of 3 decks +33% synergy
Sudden Substitution
33% of 3 decks +33% synergy
Wheel and Deal
33% of 3 decks +33% synergy
Theoretical Duplication
33% of 3 decks +33% synergy
Slaughter Pact
33% of 3 decks +33% synergy
Tainted Strike
33% of 3 decks +32% synergy
Disallow
33% of 3 decks +32% synergy
Crosis's Charm
33% of 3 decks +31% synergy
Baleful Mastery
33% of 3 decks +31% synergy
Drown in the Loch
33% of 3 decks +27% synergy
Swan Song
33% of 3 decks +17% synergy
Chaos Warp
33% of 3 decks +2% synergy
Counterspell
33% of 3 decks -9% synergy
Sorceries
Endless Swarm
100% of 1 decks +100% synergy
Enduring Ideal
100% of 1 decks +100% synergy
Doomsday
100% of 3 decks +99% synergy
Storm Herd
100% of 1 decks +99% synergy
Windfall
100% of 3 decks +87% synergy
Enter the Infinite
67% of 3 decks +66% synergy
Molten Psyche
67% of 3 decks +66% synergy
Echo of Eons
67% of 3 decks +65% synergy
Dark Deal
67% of 3 decks +64% synergy
Whispering Madness
67% of 3 decks +64% synergy
Undying Flames
33% of 3 decks +33% synergy
Neverending Torment
33% of 3 decks +33% synergy
Selective Memory
33% of 3 decks +33% synergy
Paradigm Shift
33% of 3 decks +33% synergy
Mana Severance
33% of 3 decks +33% synergy
Eternal Dominion
33% of 3 decks +33% synergy
Morality Shift
33% of 3 decks +33% synergy
Incendiary Command
33% of 3 decks +33% synergy
Dance with Calamity
33% of 3 decks +33% synergy
Thoughtseize
33% of 3 decks +33% synergy
Prosperity
33% of 3 decks +32% synergy
Wheel of Fate
33% of 3 decks +32% synergy
Commit // Memory
33% of 3 decks +32% synergy
Mind Grind
33% of 3 decks +32% synergy
Peer into the Abyss
33% of 3 decks +30% synergy
Ponder
33% of 3 decks +21% synergy
Utility Artifacts
Howling Mine
100% of 3 decks +98% synergy
Fist of Suns
100% of 1 decks +93% synergy
Anvil of Bogardan
67% of 3 decks +66% synergy
Sentinel Totem
33% of 3 decks +33% synergy
Timesifter
33% of 3 decks +33% synergy
Memory Jar
33% of 3 decks +33% synergy
Geth's Grimoire
33% of 3 decks +33% synergy
Font of Mythos
33% of 3 decks +33% synergy
Umbral Mantle
33% of 3 decks +32% synergy
Grafted Exoskeleton
33% of 3 decks +32% synergy
Teferi's Puzzle Box
33% of 3 decks +32% synergy
Soul-Guide Lantern
33% of 3 decks +32% synergy
Lithoform Engine
33% of 3 decks +32% synergy
Mindcrank
33% of 3 decks +32% synergy
Alhammarret's Archive
33% of 3 decks +32% synergy
Strionic Resonator
33% of 3 decks +30% synergy
Aetherflux Reservoir
33% of 3 decks +30% synergy
Lotus Petal
33% of 3 decks +27% synergy
Commander's Sphere
33% of 3 decks +19% synergy
Lightning Greaves
33% of 3 decks +8% synergy
Swiftfoot Boots
33% of 3 decks +6% synergy
Enchantments
Leyline of Sanctity
100% of 1 decks +100% synergy
Underworld Dreams
100% of 3 decks +98% synergy
Wilderness Reclamation
100% of 1 decks +96% synergy
Mirari's Wake
100% of 1 decks +87% synergy
Leyline of the Guildpact
100% of 1 decks +84% synergy
Glistening Oil
67% of 3 decks +66% synergy
Phyresis
67% of 3 decks +65% synergy
Fevered Visions
67% of 3 decks +65% synergy
Waste Not
67% of 3 decks +64% synergy
Spiteful Visions
67% of 3 decks +64% synergy
Leyline of Anticipation
67% of 3 decks +62% synergy
Necromancer's Magemark
33% of 3 decks +33% synergy
Shared Fate
33% of 3 decks +33% synergy
Breathstealer's Crypt
33% of 3 decks +33% synergy
Eye of the Storm
33% of 3 decks +33% synergy
Tainted Remedy
33% of 3 decks +33% synergy
Sigil of Sleep
33% of 3 decks +33% synergy
Stranglehold
33% of 3 decks +33% synergy
Pemmin's Aura
33% of 3 decks +32% synergy
Megrim
33% of 3 decks +32% synergy
Liliana's Caress
33% of 3 decks +32% synergy
Forced Fruition
33% of 3 decks +32% synergy
Phyrexian Tyranny
33% of 3 decks +32% synergy
Sunbird's Invocation
33% of 3 decks +31% synergy
Freed from the Real
33% of 3 decks +31% synergy
Curiosity
33% of 3 decks +30% synergy
Teferi's Ageless Insight
33% of 3 decks +28% synergy
Exquisite Blood
33% of 3 decks +28% synergy
Planeswalkers
Ashiok, Dream Render
100% of 3 decks +96% synergy
Ob Nixilis, the Hate-Twisted
33% of 3 decks +32% synergy
Utility Lands
Emergence Zone
67% of 3 decks +64% synergy
Bojuka Bog
67% of 3 decks +37% synergy
Witch's Clinic
33% of 3 decks +32% synergy
Restless Spire
33% of 3 decks +31% synergy
Restless Reef
33% of 3 decks +31% synergy
Geier Reach Sanitarium
33% of 3 decks +30% synergy
Command Beacon
33% of 3 decks +29% synergy
Cabal Coffers
33% of 3 decks +23% synergy
Mystic Sanctuary
33% of 3 decks +22% synergy
Otawara, Soaring City
33% of 3 decks +17% synergy
Reliquary Tower
33% of 3 decks +4% synergy
Mana Artifacts
Timeless Lotus
100% of 1 decks +88% synergy
Sol Ring
100% of 3 decks +16% synergy
Chromatic Lantern
67% of 3 decks +57% synergy
Fellwar Stone
67% of 3 decks +46% synergy
Arcane Signet
67% of 3 decks -5% synergy
The Celestus
33% of 3 decks +33% synergy
Chromatic Orrery
33% of 3 decks +32% synergy
Gilded Lotus
33% of 3 decks +30% synergy
Relic of Sauron
33% of 3 decks +25% synergy
Izzet Signet
33% of 3 decks +6% synergy
Dimir Signet
33% of 3 decks +4% synergy
Rakdos Signet
33% of 3 decks +4% synergy
Lands
Evolving Wilds
67% of 3 decks +46% synergy
Xander's Lounge
67% of 3 decks +41% synergy
Drowned Catacomb
67% of 3 decks +40% synergy
Crumbling Necropolis
67% of 3 decks +36% synergy
Dragonskull Summit
67% of 3 decks +35% synergy
Sulfur Falls
67% of 3 decks +35% synergy
Exotic Orchard
67% of 3 decks +31% synergy
Command Tower
67% of 3 decks -8% synergy
Grixis Panorama
33% of 3 decks +33% synergy
Maestros Theater
33% of 3 decks +32% synergy
Forbidden Orchard
33% of 3 decks +31% synergy
Bloodstained Mire
33% of 3 decks +23% synergy
Scalding Tarn
33% of 3 decks +23% synergy
Polluted Delta
33% of 3 decks +22% synergy
Foreboding Ruins
33% of 3 decks +17% synergy
Shipwreck Marsh
33% of 3 decks +15% synergy
Myriad Landscape
33% of 3 decks +15% synergy
Path of Ancestry
33% of 3 decks +12% synergy
Morphic Pool
33% of 3 decks +7% synergy
Luxury Suite
33% of 3 decks +7% synergy
Training Center
33% of 3 decks +6% synergy
Blood Crypt
33% of 3 decks -5% synergy
Steam Vents
33% of 3 decks -5% synergy
Watery Grave
33% of 3 decks -7% synergy