Angel of Destiny + Brudiclad, Telchor Engineer Combo

Angel of Destiny and Brudiclad on the battlefield.

Your life total is at least 5. Angel of Destiny does not have summoning sickness.

Angel of Destiny must exist on the battlefield as a token. You control three other tokens that do not have summoning sickness. Opponents cannot block flying creatures you control.

At the beginning of combat on your turn, Brudiclad triggers, creating a 2/1 blue Phyrexian Myr artifact creature token and then causing each other token you control to become a copy of your token Angel of Destiny indefinitely.

Declare all your Angels as attackers, sending at least one Angel at each opponent.

When first strike damage is dealt, each Angel of Destiny you control triggers for each creature that dealt damage.

Resolve each trigger, causing each opponent to gain life equal to X times the damage they took (where X is the number of Angels you control) and you to gain life equal to that combined total.

Repeat steps 4-5 for the normal damage step.

At the beginning of your end step, since your life total is at least 45, each Angel of Destiny you control triggers, causing the player it attacked to lose the game.

Each opponent loses the game