Syr Konrad, the Grim + Rat Colony + Secret Salvage + Tormod's Crypt

Syr Konrad, the Grim
Rat Colony
Secret Salvage
Tormod's Crypt

Requires
Syr Konrad, the Grim must be on the battlefield. Rat Colony must be in the graveyard. Secret Salvage must be in hand. Tormod's Crypt must be on the battlefield. You have a number of copies of Rat Colony in your library greater than your maximum hand size minus the number of cards in your hand. Mana needed: 3
Steps
  1. Cast Secret Salvage by paying 3, exiling Rat Colony from your graveyard and causing you to search your library for all copies of Rat Colony in your library and put them into your hand.
  2. Syr Konrad triggers, dealing 1 damage to each opponent.
  3. Move to your cleanup step, causing you to discard down to your maximum hand size, ensuring to discard as many copies of Rat Colony as possible.
  4. Syr Konrad triggers for each creature card discarded this way, dealing that much damage to each opponent.
  5. Activate Tormod's Crypt by tapping and sacrificing it, exiling your graveyard.
  6. Syr Konrad triggers for each creature card exiled this way, dealing that much damage to each opponent.
Results
Near-infinite damage.

Syr Konrad, the Grim
0.11% of 4648 decks 5 decks
Karumonix, the Rat King
0.05% of 6057 decks 3 decks
Wick, the Whorled Mind
0.02% of 5324 decks 1 decks
Vren, the Relentless
0.03% of 3942 decks 1 decks
Ashcoat of the Shadow Swarm
0.03% of 3126 decks 1 decks
High Synergy Cards
Surgical Extraction
64% of 11 decks +64% synergy
Rat Out
62% of 8 decks +62% synergy
Marrow-Gnawer
55% of 11 decks +54% synergy
Lord Skitter, Sewer King
50% of 8 decks +48% synergy
Pack Rat
45% of 11 decks +44% synergy
Witch's Cottage
45% of 11 decks +42% synergy
Diabolic Tutor
45% of 11 decks +39% synergy
Diabolic Intent
45% of 11 decks +37% synergy
Tormod's Cryptkeeper
36% of 11 decks +36% synergy
Plague of Vermin
36% of 11 decks +36% synergy
Top Cards
Dark Ritual
55% of 11 decks +32% synergy
Ratcatcher
36% of 11 decks +36% synergy
Forever Young
36% of 11 decks +36% synergy
Echoing Return
36% of 11 decks +36% synergy
Bontu's Monument
36% of 11 decks +34% synergy
Crippling Fear
36% of 11 decks +34% synergy
Ayara, First of Locthwain
36% of 11 decks +33% synergy
Grave Pact
36% of 11 decks +32% synergy
Creatures
Gnawing Vermin
38% of 8 decks +37% synergy
Twisted Sewer-Witch
38% of 8 decks +37% synergy
Voracious Vermin
38% of 8 decks +37% synergy
Tangled Colony
38% of 8 decks +37% synergy
Lord Skitter's Butcher
38% of 8 decks +37% synergy
Mirkwood Bats
38% of 8 decks +25% synergy
Relentless Rats
27% of 11 decks +27% synergy
Ravenous Rats
27% of 11 decks +27% synergy
Locust Miser
27% of 11 decks +27% synergy
Rancid Rats
27% of 11 decks +27% synergy
Chittering Witch
27% of 11 decks +26% synergy
Piper of the Swarm
27% of 11 decks +26% synergy
Burglar Rat
27% of 11 decks +26% synergy
Ogre Slumlord
27% of 11 decks +25% synergy
Instants
Bitter Triumph
43% of 7 decks +38% synergy
Vampiric Tutor
36% of 11 decks +18% synergy
Culling the Weak
27% of 11 decks +24% synergy
Village Rites
27% of 11 decks +17% synergy
Sorceries
Demonic Tutor
45% of 11 decks +23% synergy
Infectious Inquiry
38% of 8 decks +35% synergy
Grim Tutor
36% of 11 decks +32% synergy
Sign in Blood
27% of 11 decks +18% synergy
Utility Artifacts
Nim Deathmantle
27% of 11 decks +27% synergy
Thrumming Stone
27% of 11 decks +27% synergy
Jet Medallion
27% of 11 decks +24% synergy
Phyrexian Altar
27% of 11 decks +23% synergy
Herald's Horn
27% of 11 decks +21% synergy
Ashnod's Altar
27% of 11 decks +20% synergy
Enchantments
Necrogen Communion
38% of 8 decks +36% synergy
Phyrexian Arena
27% of 11 decks +12% synergy
Utility Lands
Bojuka Bog
45% of 11 decks +15% synergy
Mortuary Mire
36% of 11 decks +31% synergy
Urborg, Tomb of Yawgmoth
27% of 11 decks +18% synergy
Cabal Coffers
27% of 11 decks +16% synergy
Mana Artifacts
Sol Ring
82% of 11 decks -3% synergy
Arcane Signet
64% of 11 decks -9% synergy
Lands
Path of Ancestry
36% of 11 decks +15% synergy
Command Tower
36% of 11 decks -38% synergy
Myriad Landscape
27% of 11 decks +8% synergy