Doomsday + Commander's Sphere + Bolas's Citadel + Emergence Zone + Repay in Kind + Lich

Doomsday
Commander's Sphere
Bolas's Citadel
Emergence Zone
Repay in Kind
Lich

Requires
Doomsday must be in hand. Commander's Sphere must be on the battlefield. Bolas's Citadel must be in the graveyard, or in the library. Emergence Zone must be in the graveyard, or in the library. Repay in Kind must be in the graveyard, or in the library. Lich must be in the graveyard, or in the library. Your life total is at least 24. You have not played land this turn. Mana needed: 4
Steps
  1. Cast Doomsday by paying , searching your library and graveyard for Bolas's Citadel, Emergence Zone, Repay in Kind, Lich, and any other card, exiling all other cards from your graveyard and library, and then placing the remaining cards on top of your library in the order previously listed and losing half your life, rounded up.
  2. Activate Commander's Sphere by sacrificing it, drawing a card.
  3. Cast Bolas's Citadel by paying 3.
  4. Play Emergence Zone from the top of your library.
  5. Activate Emergence Zone by paying 1, tapping, and sacrificing it.
  6. Cast Repay in Kind from the top of your library by paying seven life.
  7. Holding priority, cast Lich from the top of your library by paying 4 life.
  8. Lich entering the battlefield, causing you to lose life equal to your life total.
  9. Resolve the Repay in Kind, causing each player's life total to become equal to the lowest life total among all players.
Results
Infinite lifeloss.

K'rrik, Son of Yawgmoth
0.03% of 13841 decks 4 decks
Zur the Enchanter
0.02% of 11095 decks 2 decks
Drana and Linvala
0.08% of 1259 decks 1 decks
Dralnu, Lich Lord
0.32% of 317 decks 1 decks
The Wise Mothman
0.01% of 12479 decks 1 decks
Saskia the Unyielding
0.02% of 5551 decks 1 decks
Alela, Cunning Conqueror
0.01% of 9954 decks 1 decks
Tinybones, the Pickpocket
0.06% of 1622 decks 1 decks
The Infamous Cruelclaw
0.02% of 4155 decks 1 decks
Massacre Girl, Known Killer
0.03% of 3946 decks 1 decks
Grenzo, Dungeon Warden
0.03% of 3267 decks 1 decks
Cao Ren, Wei Commander
3.23% of 31 decks 1 decks
High Synergy Cards
Aetherflux Reservoir
62% of 16 decks +59% synergy
Cabal Coffers
69% of 16 decks +58% synergy
Black Sun's Zenith
56% of 16 decks +55% synergy
Dark Ritual
75% of 16 decks +53% synergy
Urborg, Tomb of Yawgmoth
56% of 16 decks +46% synergy
Peer into the Abyss
47% of 15 decks +43% synergy
Necropotence
44% of 16 decks +38% synergy
Cruel Bargain
38% of 16 decks +37% synergy
Aphotic Wisps
38% of 16 decks +37% synergy
Sacrifice
38% of 16 decks +37% synergy
Top Cards
Reanimate
50% of 16 decks +34% synergy
Viscera Seer
44% of 16 decks +34% synergy
Sign in Blood
44% of 16 decks +34% synergy
Jeweled Lotus
40% of 15 decks +34% synergy
Deadly Rollick
40% of 15 decks +29% synergy
Walking Ballista
38% of 16 decks +35% synergy
Cabal Ritual
38% of 16 decks +33% synergy
Crypt Ghast
38% of 16 decks +33% synergy
Mana Vault
38% of 16 decks +31% synergy
Entomb
38% of 16 decks +30% synergy
Creatures
Vizkopa Guildmage
75% of 4 decks +73% synergy
Gray Merchant of Asphodel
38% of 16 decks +28% synergy
Sheoldred, the Apocalypse
33% of 15 decks +28% synergy
K'rrik, Son of Yawgmoth
31% of 16 decks +29% synergy
Mikaeus, the Unhallowed
31% of 16 decks +28% synergy
Orcish Bowmasters
27% of 11 decks +16% synergy
Opposition Agent
27% of 15 decks +19% synergy
Chainer, Dementia Master
25% of 16 decks +24% synergy
Dauthi Voidwalker
20% of 15 decks +12% synergy
Priest of Gix
19% of 16 decks +18% synergy
Triskelion
19% of 16 decks +18% synergy
Kokusho, the Evening Star
19% of 16 decks +17% synergy
Plaguecrafter
19% of 16 decks +14% synergy
Solemn Simulacrum
19% of 16 decks +5% synergy
Instants
Counterspell
60% of 5 decks +17% synergy
Vampiric Tutor
50% of 16 decks +32% synergy
Ad Nauseam
31% of 16 decks +28% synergy
Infernal Grasp
27% of 15 decks +19% synergy
Go for the Throat
25% of 16 decks +18% synergy
Force of Despair
19% of 16 decks +18% synergy
Tragic Slip
19% of 16 decks +15% synergy
Sorceries
Wrath of God
75% of 4 decks +68% synergy
Demonic Tutor
62% of 16 decks +40% synergy
Damnation
38% of 16 decks +29% synergy
Toxic Deluge
38% of 16 decks +20% synergy
Imperial Seal
31% of 16 decks +25% synergy
Feed the Swarm
27% of 15 decks +8% synergy
Thoughtseize
25% of 16 decks +24% synergy
Buried Alive
25% of 16 decks +19% synergy
Night's Whisper
25% of 16 decks +16% synergy
Infernal Contract
19% of 16 decks +19% synergy
Bubbling Muck
19% of 16 decks +17% synergy
Exsanguinate
19% of 16 decks +13% synergy
Diabolic Tutor
19% of 16 decks +12% synergy
Read the Bones
19% of 16 decks +11% synergy
Diabolic Intent
19% of 16 decks +10% synergy
Utility Artifacts
Jet Medallion
31% of 16 decks +28% synergy
The One Ring
27% of 11 decks +18% synergy
Sensei's Divining Top
25% of 16 decks +19% synergy
Defense Grid
19% of 16 decks +18% synergy
Lightning Greaves
19% of 16 decks -7% synergy
Enchantments
Black Market Connections
33% of 15 decks +22% synergy
Phyrexian Arena
31% of 16 decks +16% synergy
Animate Dead
25% of 16 decks +16% synergy
Lich's Mastery
19% of 16 decks +18% synergy
Utility Lands
Otawara, Soaring City
60% of 5 decks +43% synergy
Bojuka Bog
50% of 16 decks +20% synergy
Reliquary Tower
38% of 16 decks +8% synergy
Nykthos, Shrine to Nyx
31% of 16 decks +26% synergy
Phyrexian Tower
31% of 16 decks +23% synergy
Ancient Tomb
31% of 16 decks +21% synergy
Takenuma, Abandoned Mire
27% of 15 decks +16% synergy
Cabal Stronghold
25% of 16 decks +21% synergy
Urza's Saga
20% of 15 decks +13% synergy
Volrath's Stronghold
19% of 16 decks +17% synergy
Maze of Ith
19% of 16 decks +16% synergy
Strip Mine
19% of 16 decks +16% synergy
High Market
19% of 16 decks +16% synergy
Witch's Cottage
19% of 16 decks +15% synergy
Mana Artifacts
Arcane Signet
88% of 16 decks +16% synergy
Sol Ring
88% of 16 decks +3% synergy
Orzhov Signet
75% of 4 decks +48% synergy
Dimir Signet
60% of 5 decks +30% synergy
Thought Vessel
38% of 16 decks +21% synergy
Lotus Petal
31% of 16 decks +25% synergy
Mana Crypt
31% of 16 decks +22% synergy
Mox Amber
25% of 16 decks +21% synergy
Chrome Mox
25% of 16 decks +19% synergy
Mind Stone
19% of 16 decks +1% synergy
Fellwar Stone
19% of 16 decks -2% synergy
Lands
Vault of Champions
100% of 3 decks +74% synergy
Luxury Suite
100% of 3 decks +74% synergy
Blood Crypt
100% of 3 decks +61% synergy
Godless Shrine
100% of 4 decks +59% synergy
Command Tower
56% of 16 decks -18% synergy
Polluted Delta
31% of 16 decks +20% synergy
Prismatic Vista
25% of 16 decks +19% synergy
Bloodstained Mire
25% of 16 decks +15% synergy
Marsh Flats
25% of 16 decks +14% synergy
Path of Ancestry
25% of 16 decks +4% synergy
Gemstone Caverns
19% of 16 decks +14% synergy
Cavern of Souls
19% of 16 decks +12% synergy
Verdant Catacombs
19% of 16 decks +7% synergy
Evolving Wilds
19% of 16 decks -2% synergy