Doomsday + Commander's Sphere + Bolas's Citadel + Emergence Zone + Repay in Kind + Lich

Doomsday
Commander's Sphere
Bolas's Citadel
Emergence Zone
Repay in Kind
Lich

Requires
Doomsday must be in hand. Commander's Sphere must be on the battlefield. Bolas's Citadel must be in the graveyard, or in the library. Emergence Zone must be in the graveyard, or in the library. Repay in Kind must be in the graveyard, or in the library. Lich must be in the graveyard, or in the library. Your life total is at least 24. You have not played land this turn. Mana needed: 4
Steps
  1. Cast Doomsday by paying , searching your library and graveyard for Bolas's Citadel, Emergence Zone, Repay in Kind, Lich, and any other card, exiling all other cards from your graveyard and library, and then placing the remaining cards on top of your library in the order previously listed and losing half your life, rounded up.
  2. Activate Commander's Sphere by sacrificing it, drawing a card.
  3. Cast Bolas's Citadel by paying 3.
  4. Play Emergence Zone from the top of your library.
  5. Activate Emergence Zone by paying 1, tapping, and sacrificing it.
  6. Cast Repay in Kind from the top of your library by paying seven life.
  7. Holding priority, cast Lich from the top of your library by paying 4 life.
  8. Lich entering the battlefield, causing you to lose life equal to your life total.
  9. Resolve the Repay in Kind, causing each player's life total to become equal to the lowest life total among all players.
Results
Infinite lifeloss.

K'rrik, Son of Yawgmoth
0.03% of 14145 decks 4 decks
Zur the Enchanter
0.02% of 11235 decks 2 decks
Drana and Linvala
0.08% of 1327 decks 1 decks
Dralnu, Lich Lord
0.31% of 325 decks 1 decks
Massacre Girl, Known Killer
0.02% of 4207 decks 1 decks
Saskia the Unyielding
0.02% of 5561 decks 1 decks
Obzedat, Ghost Council
0.13% of 749 decks 1 decks
The Wise Mothman
0.01% of 13356 decks 1 decks
Alela, Cunning Conqueror
0.01% of 10521 decks 1 decks
Tinybones, the Pickpocket
0.06% of 1681 decks 1 decks
Cao Ren, Wei Commander
2.86% of 35 decks 1 decks
The Infamous Cruelclaw
0.02% of 4515 decks 1 decks
Grenzo, Dungeon Warden
0.03% of 3292 decks 1 decks
High Synergy Cards
Wrath of God
80% of 5 decks +73% synergy
Aetherflux Reservoir
65% of 17 decks +61% synergy
Cabal Coffers
71% of 17 decks +60% synergy
Black Sun's Zenith
53% of 17 decks +51% synergy
Dark Ritual
71% of 17 decks +48% synergy
Urborg, Tomb of Yawgmoth
53% of 17 decks +43% synergy
Necropotence
47% of 17 decks +42% synergy
Peer into the Abyss
44% of 16 decks +41% synergy
Cruel Bargain
35% of 17 decks +35% synergy
Aphotic Wisps
35% of 17 decks +35% synergy
Top Cards
Reanimate
47% of 17 decks +31% synergy
Gray Merchant of Asphodel
41% of 17 decks +32% synergy
Viscera Seer
41% of 17 decks +32% synergy
Sign in Blood
41% of 17 decks +31% synergy
Toxic Deluge
41% of 17 decks +24% synergy
Jeweled Lotus
38% of 16 decks +32% synergy
Deadly Rollick
38% of 16 decks +27% synergy
Sacrifice
35% of 17 decks +34% synergy
K'rrik, Son of Yawgmoth
35% of 17 decks +33% synergy
Walking Ballista
35% of 17 decks +33% synergy
Creatures
Vizkopa Guildmage
60% of 5 decks +58% synergy
Crypt Ghast
35% of 17 decks +30% synergy
Sheoldred, the Apocalypse
31% of 16 decks +26% synergy
Mikaeus, the Unhallowed
29% of 17 decks +27% synergy
Orcish Bowmasters
27% of 11 decks +16% synergy
Opposition Agent
25% of 16 decks +18% synergy
Chainer, Dementia Master
24% of 17 decks +23% synergy
Kokusho, the Evening Star
24% of 17 decks +22% synergy
Dauthi Voidwalker
19% of 16 decks +11% synergy
Priest of Gix
18% of 17 decks +17% synergy
Triskelion
18% of 17 decks +17% synergy
Plaguecrafter
18% of 17 decks +13% synergy
Solemn Simulacrum
18% of 17 decks +4% synergy
Instants
Anguished Unmaking
60% of 5 decks +36% synergy
Counterspell
60% of 5 decks +17% synergy
Path to Exile
60% of 5 decks +14% synergy
Vampiric Tutor
53% of 17 decks +35% synergy
Ad Nauseam
35% of 17 decks +32% synergy
Cabal Ritual
35% of 17 decks +31% synergy
Entomb
35% of 17 decks +28% synergy
Infernal Grasp
25% of 16 decks +18% synergy
Go for the Throat
24% of 17 decks +16% synergy
Force of Despair
18% of 17 decks +16% synergy
Tragic Slip
18% of 17 decks +14% synergy
Sorceries
Demonic Tutor
65% of 17 decks +43% synergy
Austere Command
60% of 5 decks +47% synergy
Imperial Seal
35% of 17 decks +30% synergy
Damnation
35% of 17 decks +27% synergy
Feed the Swarm
25% of 16 decks +7% synergy
Thoughtseize
24% of 17 decks +23% synergy
Buried Alive
24% of 17 decks +18% synergy
Night's Whisper
24% of 17 decks +14% synergy
Infernal Contract
18% of 17 decks +18% synergy
Bubbling Muck
18% of 17 decks +16% synergy
Exsanguinate
18% of 17 decks +12% synergy
Diabolic Tutor
18% of 17 decks +11% synergy
Read the Bones
18% of 17 decks +10% synergy
Diabolic Intent
18% of 17 decks +9% synergy
Utility Artifacts
Jet Medallion
29% of 17 decks +27% synergy
The One Ring
27% of 11 decks +18% synergy
Sensei's Divining Top
24% of 17 decks +18% synergy
Defense Grid
18% of 17 decks +17% synergy
Phyrexian Altar
18% of 17 decks +14% synergy
Ashnod's Altar
18% of 17 decks +10% synergy
Lightning Greaves
18% of 17 decks -8% synergy
Enchantments
Axis of Mortality
60% of 5 decks +60% synergy
Phyrexian Arena
35% of 17 decks +20% synergy
Black Market Connections
31% of 16 decks +20% synergy
Lich's Mastery
24% of 17 decks +23% synergy
Animate Dead
24% of 17 decks +14% synergy
Phyrexian Reclamation
18% of 17 decks +14% synergy
Utility Lands
Hall of Heliod's Generosity
60% of 5 decks +53% synergy
Otawara, Soaring City
60% of 5 decks +43% synergy
Bojuka Bog
47% of 17 decks +17% synergy
Reliquary Tower
41% of 17 decks +12% synergy
Nykthos, Shrine to Nyx
29% of 17 decks +24% synergy
Phyrexian Tower
29% of 17 decks +21% synergy
Ancient Tomb
29% of 17 decks +19% synergy
Takenuma, Abandoned Mire
25% of 16 decks +14% synergy
Cabal Stronghold
24% of 17 decks +20% synergy
Urza's Saga
19% of 16 decks +12% synergy
Volrath's Stronghold
18% of 17 decks +16% synergy
Maze of Ith
18% of 17 decks +15% synergy
Strip Mine
18% of 17 decks +15% synergy
High Market
18% of 17 decks +15% synergy
Witch's Cottage
18% of 17 decks +14% synergy
Castle Locthwain
18% of 17 decks +12% synergy
Mana Artifacts
Sol Ring
88% of 17 decks +4% synergy
Arcane Signet
82% of 17 decks +10% synergy
Orzhov Signet
80% of 5 decks +53% synergy
Dimir Signet
60% of 5 decks +30% synergy
Mana Vault
35% of 17 decks +29% synergy
Thought Vessel
35% of 17 decks +18% synergy
Lotus Petal
29% of 17 decks +23% synergy
Mana Crypt
29% of 17 decks +21% synergy
Mox Amber
24% of 17 decks +19% synergy
Chrome Mox
24% of 17 decks +17% synergy
Mind Stone
18% of 17 decks +0% synergy
Fellwar Stone
18% of 17 decks -3% synergy
Lands
Vault of Champions
100% of 4 decks +74% synergy
Luxury Suite
100% of 3 decks +74% synergy
Blood Crypt
100% of 3 decks +61% synergy
Godless Shrine
100% of 5 decks +59% synergy
Orzhov Basilica
60% of 5 decks +44% synergy
Caves of Koilos
60% of 5 decks +32% synergy
Command Tower
59% of 17 decks -15% synergy
Polluted Delta
29% of 17 decks +18% synergy
Prismatic Vista
24% of 17 decks +18% synergy
Bloodstained Mire
24% of 17 decks +13% synergy
Marsh Flats
24% of 17 decks +12% synergy
Evolving Wilds
24% of 17 decks +3% synergy
Path of Ancestry
24% of 17 decks +2% synergy
Gemstone Caverns
18% of 17 decks +13% synergy
Cavern of Souls
18% of 17 decks +11% synergy
Verdant Catacombs
18% of 17 decks +6% synergy