Yawgmoth, Thran Physician + Crystalline Crawler + Mindless Automaton + Vorinclex, Monstrous Raider

Yawgmoth, Thran Physician
Crystalline Crawler
Mindless Automaton
Vorinclex, Monstrous Raider

Requires
Yawgmoth, Thran Physician must be on the battlefield. Crystalline Crawler must be on the battlefield. Mindless Automaton must be on the battlefield. Vorinclex, Monstrous Raider must be on the battlefield. You have at least one card in hand. Crystalline Crawler and Mindless Automaton have at least one +1/+1 counter on them. Mana needed:
Steps
  1. Activate Yawgmoth's second ability by paying and discarding a card, causing you to put two +1/+1 counters on Crystalline Crawler and Mindless Automaton.
  2. Activate Crystalline Crawler's first ability twice by removing two +1/+1 counters from it, adding .
  3. Activate Mindless Automaton's second ability by removing two +1/+1 counters from it, causing you to draw a card.
  4. Repeat.
Results
Infinite draw triggers. Infinite looting. Infinite self-discard triggers. Near-infinite proliferate.

Atraxa, Praetors' Voice
0.03% of 35211 decks 9 decks
Ghave, Guru of Spores
0.03% of 6423 decks 2 decks
Reyhan, Last of the Abzan // Sakashima of a Thousand Faces
0.74% of 270 decks 2 decks
Volrath, the Shapestealer
0.04% of 2776 decks 1 decks
Mazirek, Kraul Death Priest
0.05% of 1960 decks 1 decks
Indoraptor, the Perfect Hybrid
0.02% of 4089 decks 1 decks
Ishai, Ojutai Dragonspeaker // Reyhan, Last of the Abzan
0.06% of 1569 decks 1 decks
High Synergy Cards
Tekuthal, Inquiry Dominus
75% of 12 decks +72% synergy
Winding Constrictor
71% of 17 decks +67% synergy
Fathom Mage
69% of 13 decks +65% synergy
Ezuri, Stalker of Spheres
67% of 12 decks +63% synergy
Toothy, Imaginary Friend
62% of 13 decks +61% synergy
Pir, Imaginative Rascal
59% of 17 decks +58% synergy
Walking Ballista
59% of 17 decks +56% synergy
Karn's Bastion
59% of 17 decks +54% synergy
Bristly Bill, Spine Sower
57% of 7 decks +52% synergy
Deepglow Skate
54% of 13 decks +52% synergy
Top Cards
Esper Sentinel
58% of 12 decks +38% synergy
Inexorable Tide
54% of 13 decks +51% synergy
Kami of Whispered Hopes
53% of 15 decks +46% synergy
Evolution Sage
53% of 17 decks +46% synergy
Doubling Season
53% of 17 decks +44% synergy
Hardened Scales
53% of 17 decks +44% synergy
The Great Henge
53% of 17 decks +43% synergy
Birds of Paradise
53% of 17 decks +26% synergy
Grateful Apparition
50% of 12 decks +48% synergy
Mikaeus, the Lunarch
42% of 12 decks +39% synergy
Creatures
Corpsejack Menace
41% of 17 decks +36% synergy
Thrummingbird
38% of 13 decks +35% synergy
Spark Double
38% of 13 decks +31% synergy
Triskelion
35% of 17 decks +35% synergy
Lae'zel, Vlaakith's Champion
33% of 12 decks +30% synergy
Conclave Mentor
33% of 12 decks +29% synergy
Shalai, Voice of Plenty
33% of 12 decks +26% synergy
Prime Speaker Zegana
31% of 13 decks +28% synergy
Vorel of the Hull Clade
31% of 13 decks +28% synergy
Herald of Secret Streams
31% of 13 decks +28% synergy
Master Biomancer
31% of 13 decks +27% synergy
Gyre Sage
29% of 17 decks +26% synergy
Forgotten Ancient
29% of 17 decks +23% synergy
Feral Ghoul
25% of 12 decks +24% synergy
Tainted Observer
25% of 12 decks +23% synergy
Cankerbloom
25% of 16 decks +18% synergy
Faeburrow Elder
25% of 12 decks +13% synergy
Hangarback Walker
24% of 17 decks +23% synergy
Kalonian Hydra
24% of 17 decks +21% synergy
Rishkar, Peema Renegade
24% of 17 decks +19% synergy
Carrion Feeder
24% of 17 decks +18% synergy
Champion of Lambholt
24% of 17 decks +17% synergy
Myojin of Seeing Winds
23% of 13 decks +23% synergy
Flux Channeler
23% of 13 decks +20% synergy
Benevolent Hydra
19% of 16 decks +17% synergy
Drivnod, Carnage Dominus
19% of 16 decks +15% synergy
Defiler of Vigor
19% of 16 decks +15% synergy
Etched Oracle
18% of 17 decks +18% synergy
Yahenni, Undying Partisan
18% of 17 decks +14% synergy
Elves of Deep Shadow
18% of 17 decks +7% synergy
Instants
Swords to Plowshares
42% of 12 decks -21% synergy
Teferi's Protection
33% of 12 decks +13% synergy
Path to Exile
33% of 12 decks -12% synergy
Cyclonic Rift
31% of 13 decks +3% synergy
Vampiric Tutor
29% of 17 decks +11% synergy
Heroic Intervention
29% of 17 decks -0% synergy
Assassin's Trophy
29% of 17 decks -1% synergy
Inspiring Call
24% of 17 decks +16% synergy
Beast Within
24% of 17 decks -15% synergy
Mana Drain
23% of 13 decks +8% synergy
Fierce Guardianship
23% of 13 decks +5% synergy
Counterspell
23% of 13 decks -20% synergy
Infectious Bite
19% of 16 decks +17% synergy
Worldly Tutor
18% of 17 decks +3% synergy
Sorceries
Three Visits
41% of 17 decks +16% synergy
Farseek
41% of 17 decks +7% synergy
Tezzeret's Gambit
38% of 13 decks +35% synergy
Nature's Lore
35% of 17 decks +3% synergy
Unnatural Restoration
19% of 16 decks +15% synergy
Life's Legacy
18% of 17 decks +16% synergy
Demonic Tutor
18% of 17 decks -5% synergy
Utility Artifacts
Sword of Truth and Justice
41% of 17 decks +40% synergy
Ozolith, the Shattered Spire
40% of 15 decks +34% synergy
Contagion Engine
35% of 17 decks +34% synergy
The Ozolith
35% of 17 decks +32% synergy
Lux Cannon
29% of 17 decks +29% synergy
Lightning Greaves
29% of 17 decks +4% synergy
Ashnod's Altar
18% of 17 decks +10% synergy
Skullclamp
18% of 17 decks +5% synergy
Swiftfoot Boots
18% of 17 decks -10% synergy
Enchantments
Innkeeper's Talent
100% of 3 decks +91% synergy
Branching Evolution
35% of 17 decks +30% synergy
Rhystic Study
31% of 13 decks +3% synergy
Parallax Wave
25% of 12 decks +25% synergy
Resourceful Defense
25% of 12 decks +24% synergy
Smothering Tithe
25% of 12 decks -0% synergy
Sylvan Library
24% of 17 decks +12% synergy
Simic Ascendancy
23% of 13 decks +18% synergy
Greater Good
18% of 17 decks +13% synergy
Planeswalkers
Vraska, Betrayal's Sting
31% of 16 decks +28% synergy
Tamiyo, Field Researcher
30% of 10 decks +25% synergy
Utility Lands
Gavony Township
42% of 12 decks +32% synergy
Boseiju, Who Endures
31% of 16 decks +12% synergy
Nesting Grounds
29% of 17 decks +28% synergy
Otawara, Soaring City
25% of 12 decks +8% synergy
Urborg, Tomb of Yawgmoth
24% of 17 decks +14% synergy
High Market
18% of 17 decks +15% synergy
Yavimaya, Cradle of Growth
18% of 17 decks +8% synergy
Rogue's Passage
18% of 17 decks -2% synergy
Reliquary Tower
18% of 17 decks -12% synergy
Mana Artifacts
Sol Ring
71% of 17 decks -14% synergy
Arcane Signet
59% of 17 decks -13% synergy
Astral Cornucopia
41% of 17 decks +40% synergy
Staff of Compleation
38% of 16 decks +36% synergy
Everflowing Chalice
29% of 17 decks +25% synergy
Pentad Prism
24% of 17 decks +23% synergy
Empowered Autogenerator
18% of 17 decks +17% synergy
Lands
Breeding Pool
100% of 13 decks +59% synergy
Command Tower
94% of 17 decks +20% synergy
Overgrown Tomb
88% of 17 decks +46% synergy
Watery Grave
85% of 13 decks +44% synergy
Temple Garden
83% of 12 decks +43% synergy
Verdant Catacombs
82% of 17 decks +71% synergy
Hallowed Fountain
80% of 10 decks +39% synergy
Polluted Delta
71% of 17 decks +59% synergy
Misty Rainforest
71% of 17 decks +59% synergy
Spara's Headquarters
60% of 10 decks +28% synergy
Windswept Heath
59% of 17 decks +48% synergy
Marsh Flats
59% of 17 decks +47% synergy
Godless Shrine
58% of 12 decks +18% synergy
Zagoth Triome
54% of 13 decks +23% synergy
Flooded Strand
53% of 17 decks +42% synergy
Exotic Orchard
47% of 17 decks +12% synergy
Indatha Triome
42% of 12 decks +10% synergy
Raffine's Tower
40% of 10 decks +12% synergy
Rejuvenating Springs
38% of 13 decks +10% synergy
Bountiful Promenade
33% of 12 decks +9% synergy
Flooded Grove
31% of 13 decks +19% synergy
Morphic Pool
31% of 13 decks +5% synergy
Reflecting Pool
29% of 17 decks +24% synergy
Mana Confluence
29% of 17 decks +22% synergy
City of Brass
29% of 17 decks +21% synergy
Vault of Champions
25% of 12 decks -1% synergy
Twilight Mire
24% of 17 decks +14% synergy
Undergrowth Stadium
24% of 17 decks -3% synergy
Woodland Cemetery
24% of 17 decks -4% synergy
Hinterland Harbor
23% of 13 decks -4% synergy
Gemstone Mine
18% of 17 decks +17% synergy
Wooded Foothills
18% of 17 decks +7% synergy
Bloodstained Mire
18% of 17 decks +7% synergy
Scalding Tarn
18% of 17 decks +7% synergy
Bayou
18% of 17 decks +4% synergy