Uro, Titan of Nature's Wrath + Deadeye Navigator + Simic Growth Chamber + Spelunking
Uro, Titan of Nature's Wrath
Deadeye Navigator
Simic Growth Chamber
Spelunking
Requires
Uro, Titan of Nature's Wrath must be in hand, or in the command zone.
Deadeye Navigator must be on the battlefield.
Simic Growth Chamber must be in hand.
Spelunking must be on the battlefield.
Mana needed: 
plus enough mana to pay for commander tax, if applicable
plus enough mana to pay for commander tax, if applicable
Steps
- Cast Uro either from your hand or from the command zone by paying plus commander tax, if applicable.
- When Uro enters the battlefield, its first and second abilities trigger, as well as Deadeye Navigator's soulbond ability.
- Resolve the Deadeye Navigator trigger, pairing it and Uro.
- Resolve the second Uro trigger, causing you to draw a card, gain 3 life, and put Simic Growth Chamber from your hand onto the battlefield.
- When Simic Growth Chamber enters the battlefield untapped due to Spelunking, it triggers.
- Holding priority, activate Simic Growth Chamber by tapping it, adding .
- Resolve the Simic Growth Chamber trigger, returning it to your hand from the battlefield.
- Activate Uro by paying , blinking it.
- Repeat from step 2.
Results
Infinite card draw. Infinite draw triggers. Near-infinite ETB. Near-infinite landfall triggers. Near-infinite lifegain. Near-infinite lifegain triggers. Near-infinite LTB.
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Simic Signet
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Lands
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+52% synergy
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+32% synergy
Lush Portico
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Talon Gates of Madara
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Breeding Pool
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Horizon of Progress
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+33% synergy
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40% of 161 decks
+29% synergy
Boros Garrison
40% of 10 decks
+25% synergy
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40% of 10 decks
+4% synergy
Fabled Passage
39% of 161 decks
+30% synergy
Bountiful Landscape
38% of 8 decks
+22% synergy
Lazotep Quarry
37% of 106 decks
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Flooded Grove
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+24% synergy
Woodland Cemetery
36% of 77 decks
+8% synergy
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34% of 161 decks
+5% synergy
Izzet Boilerworks
33% of 12 decks
+17% synergy
Cinder Glade
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-5% synergy
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-6% synergy
Evolving Wilds
32% of 161 decks
+11% synergy
Overflowing Basin
32% of 131 decks
+22% synergy
Verdant Catacombs
32% of 161 decks
+20% synergy
Temple of Mystery
31% of 161 decks
+14% synergy
Hedge Maze
31% of 140 decks
+17% synergy
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+14% synergy
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30% of 161 decks
+3% synergy
Jetmir's Garden
30% of 10 decks
-3% synergy
Sunken Hollow
30% of 77 decks
-5% synergy
Urza's Cave
30% of 124 decks
+26% synergy
Simic Guildgate
30% of 161 decks
+24% synergy