Embiggen + Werewolf Pack Leader + Artificial Evolution + Amoeboid Changeling
Embiggen
Werewolf Pack Leader
Artificial Evolution
Amoeboid Changeling
Requires
Embiggen must be in hand.
Werewolf Pack Leader must be on the battlefield.
Artificial Evolution must be in hand.
Amoeboid Changeling must be on the battlefield.
Amoeboid Changeling and Werewolf Pack Leader do not have summoning sickness.
Mana needed: 
Steps
- Cast Artificial Evolution by paying , replacing all instances of the word "Human" on Werewolf Pack Leader with "Brushwagg".
- Activate Amoeboid Changeling's first activated ability by tapping it, giving Werewolf Pack Leader all creature types until end of turn.
- Activate Werewolf Pack Leader's last ability by paying , making it a 5/3 trample creature that isn't a Brushwagg until end of turn.
- Cast Embiggen by paying , giving Werewolf Pack Leader at least +264/+264 until end of turn.
- Declare Werewolf Pack leader as an attacker.
Results
Near-infinite combat damage to an opponent. Near-infinitely large creature.
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