Requires

Anhelo, the Painter must be on the battlefield. Twinning Staff must be on the battlefield. Howl of the Horde must be in hand. Infectious Inquiry must be in hand. You control at least one creature with power two or greater. You have attacked this turn. You have not cast an instant and/or sorcery spell this turn. Your life total is at least twenty-one. Your deck size is at least twenty-one. Mana needed:

Steps

1. Cast Howl of the Horde by paying and sacrificing a creature with power two or greater.
2. Howl of the Horde's casualty ability triggers, creating two copies of it due to Twinning Staff.
3. Resolve each Howl of the Horde, causing you to copy the next instant or sorcery spell you cast six times.
4. Cast Infectious Inquiry by paying .
5. Each Howl of the Horde triggers, copying Infectious Inquiry a total of nine times due to Twinning Staff.
6. Resolve each Infectious Inquiry, causing each opponent to get ten poison counters, and causing you to lose twenty life and draw twenty cards.
7. Each opponent loses the game due to having ten or more poison counters.

Results