Worldfire + Tidal Barracuda + Cauldron Familiar

Worldfire
Tidal Barracuda
Cauldron Familiar

Requires
Worldfire must be in hand. Tidal Barracuda must be on the battlefield. Cauldron Familiar must be in hand. Mana needed: 6
Steps
  1. Cast Cauldron Familiar by paying .
  2. When Cauldron Familiar enters the battlefield, it triggers.
  3. Holding priority, cast Worldfire by paying 6, exiling all permanents, all cards in all hands and graveyards, and setting each player's life total to one.
  4. Resolve the Voldran Epicure trigger from step 2, causing each opponent to lose 1 life and you to gain 1 life.
  5. Each opponent loses the game due to having 0 or less life.
Results
Each opponent loses the game. Exile all cards in all hands and graveyards. Exile all permanents. Near-infinite lifeloss.

Cecily, Haunted Mage
0.22% of 445 decks 1 decks
Creatures
Sentinel of the Pearl Trident
100% of 1 decks +100% synergy
Master of Predicaments
100% of 1 decks +100% synergy
Blisterspit Gremlin
100% of 1 decks +100% synergy
Hypersonic Dragon
100% of 1 decks +100% synergy
Galvanoth
100% of 1 decks +100% synergy
Najal, the Storm Runner
100% of 1 decks +99% synergy
Voldaren Epicure
100% of 1 decks +99% synergy
Worldgorger Dragon
100% of 1 decks +99% synergy
Mogis, God of Slaughter
100% of 1 decks +99% synergy
Thassa, God of the Sea
100% of 1 decks +97% synergy
Brudiclad, Telchor Engineer
100% of 1 decks +96% synergy
Kami of the Crescent Moon
100% of 1 decks +95% synergy
Guttersnipe
100% of 1 decks +94% synergy
Notion Thief
100% of 1 decks +91% synergy
Instants
Teferi's Time Twist
100% of 1 decks +98% synergy
Essence Flux
100% of 1 decks +97% synergy
Force of Negation
100% of 1 decks +91% synergy
Mystical Tutor
100% of 1 decks +85% synergy
Mana Drain
100% of 1 decks +84% synergy
Swan Song
100% of 1 decks +83% synergy
Brainstorm
100% of 1 decks +81% synergy
Negate
100% of 1 decks +76% synergy
Arcane Denial
100% of 1 decks +72% synergy
Counterspell
100% of 1 decks +55% synergy
Sorceries
Last Thoughts
100% of 1 decks +100% synergy
Cerebral Eruption
100% of 1 decks +100% synergy
End the Festivities
100% of 1 decks +100% synergy
Overmaster
100% of 1 decks +100% synergy
Apex of Power
100% of 1 decks +100% synergy
Personal Tutor
100% of 1 decks +99% synergy
Aminatou's Augury
100% of 1 decks +99% synergy
Call Forth the Tempest
100% of 1 decks +97% synergy
Read the Bones
100% of 1 decks +96% synergy
Diabolic Tutor
100% of 1 decks +94% synergy
Decree of Pain
100% of 1 decks +93% synergy
Ponder
100% of 1 decks +89% synergy
Demonic Tutor
100% of 1 decks +76% synergy
Utility Artifacts
Dolmen Gate
100% of 1 decks +100% synergy
Scroll Rack
100% of 1 decks +99% synergy
Vedalken Orrery
100% of 1 decks +99% synergy
Sword of the Animist
100% of 1 decks +98% synergy
Trailblazer's Boots
100% of 1 decks +98% synergy
Winged Boots
100% of 1 decks +97% synergy
Howling Mine
100% of 1 decks +94% synergy
Enchantments
Crackling Perimeter
100% of 1 decks +100% synergy
Awesome Presence
100% of 1 decks +100% synergy
Cloak of Mists
100% of 1 decks +100% synergy
Combat Research
100% of 1 decks +100% synergy
Outpost Siege
100% of 1 decks +100% synergy
Aether Tunnel
100% of 1 decks +98% synergy
Exquisite Blood
100% of 1 decks +98% synergy
Leyline of Anticipation
100% of 1 decks +97% synergy
Dictate of Kruphix
100% of 1 decks +96% synergy
Aqueous Form
100% of 1 decks +96% synergy
Rhystic Study
100% of 1 decks +73% synergy
Planeswalkers
Jeska, Thrice Reborn
100% of 1 decks +100% synergy
Chandra, Awakened Inferno
100% of 1 decks +100% synergy
Utility Lands
Basilisk Gate
100% of 1 decks +100% synergy
Boseiju, Who Shelters All
100% of 1 decks +99% synergy
Emergence Zone
100% of 1 decks +99% synergy
Reliquary Tower
100% of 1 decks +66% synergy
Mana Artifacts
Obelisk of Grixis
100% of 1 decks +97% synergy
Arcane Signet
100% of 1 decks +12% synergy
Sol Ring
100% of 1 decks +9% synergy
Lands
Sea Gate
100% of 1 decks +99% synergy
Cliffgate
100% of 1 decks +99% synergy
Black Dragon Gate
100% of 1 decks +99% synergy
Rakdos Guildgate
100% of 1 decks +98% synergy
Dimir Guildgate
100% of 1 decks +98% synergy
Izzet Guildgate
100% of 1 decks +98% synergy
Grixis Panorama
100% of 1 decks +94% synergy
Maestros Theater
100% of 1 decks +86% synergy
Myriad Landscape
100% of 1 decks +86% synergy
Terramorphic Expanse
100% of 1 decks +76% synergy
Luxury Suite
100% of 1 decks +66% synergy
Morphic Pool
100% of 1 decks +66% synergy
Training Center
100% of 1 decks +65% synergy
Drowned Catacomb
100% of 1 decks +60% synergy
Dragonskull Summit
100% of 1 decks +58% synergy
Sulfur Falls
100% of 1 decks +57% synergy
Xander's Lounge
100% of 1 decks +56% synergy