Yawgmoth, Thran Physician + Fiend Hunter + Karmic Guide + Soul's Attendant
Yawgmoth, Thran Physician
Fiend Hunter
Karmic Guide
Soul's Attendant
Requires
Yawgmoth, Thran Physician must be on the battlefield.
Fiend Hunter must be in hand.
Karmic Guide must be on the battlefield.
Soul's Attendant must be on the battlefield.
Mana needed: 
Steps
- Cast Fiend Hunter by paying .
- Fiend Hunter enters the battlefield, triggering itself and Soul's Attendant.
- Resolve the Fiend Hunter trigger, exiling Karmic Guide.
- Resolve the Soul's Attendant trigger, causing you to gain 1 life.
- Activate Yawgmoth by paying 1 life and sacrificing Fiend Hunter.
- Fiend Hunter triggers, returning Karmic Guide from exile to the battlefield.
- Karmic Guide enters the battlefield, triggering itself and Soul's Attendant.
- Resolve the Karmic Guide trigger, returning Fiend Hunter from your graveyard to the battlefield.
- Fiend Hunter enters the battlefield, triggering itself and Soul's Attendant.
- Resolve the Fiend Hunter trigger, exiling Karmic Guide.
- Resolve both remaining Soul's Attendant triggers, causing you to gain two life.
- Resolve the Yawgmoth ability from step 5, putting a -1/-1 counter on up to one creature and drawing a card.
- Repeat from step 5.
Results
Infinite card draw. Infinite draw triggers. Near-infinite -1/-1 counters. Near-infinite death triggers. Near-infinite ETB. Near-infinite lifegain triggers. Near-infinite LTB. Near-infinite sacrifice triggers.
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Mana Artifacts
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+41% synergy
Talisman of Hierarchy
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32% of 38 decks
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Mind Stone
24% of 38 decks
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Fellwar Stone
16% of 38 decks
-5% synergy
Thought Vessel
11% of 38 decks
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Lands
Sacred Foundry
100% of 3 decks
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Blood Crypt
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Command Tower
89% of 38 decks
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Godless Shrine
87% of 38 decks
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Isolated Chapel
76% of 38 decks
+49% synergy
Fetid Heath
68% of 38 decks
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Caves of Koilos
68% of 38 decks
+40% synergy
Marsh Flats
66% of 38 decks
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Vault of Champions
59% of 37 decks
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Brightclimb Pathway
46% of 37 decks
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Shattered Sanctum
38% of 37 decks
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Forbidden Orchard
37% of 38 decks
+34% synergy
Shadowy Backstreet
35% of 17 decks
+22% synergy
Plaza of Heroes
34% of 35 decks
+31% synergy
Concealed Courtyard
29% of 38 decks
+23% synergy
City of Brass
29% of 38 decks
+21% synergy
Tainted Field
29% of 38 decks
+16% synergy
Silent Clearing
26% of 38 decks
+22% synergy
Talon Gates of Madara
25% of 12 decks
+22% synergy
Windswept Heath
21% of 38 decks
+11% synergy
Orzhov Basilica
21% of 38 decks
+5% synergy
Cavern of Souls
18% of 38 decks
+12% synergy
Bloodstained Mire
18% of 38 decks
+8% synergy
Polluted Delta
18% of 38 decks
+7% synergy
Shineshadow Snarl
16% of 37 decks
+4% synergy
Flooded Strand
16% of 38 decks
+5% synergy
Verdant Catacombs
16% of 38 decks
+4% synergy
Scrubland
16% of 38 decks
+2% synergy
Exotic Orchard
16% of 38 decks
-20% synergy
Prismatic Vista
13% of 38 decks
+8% synergy
Temple of Silence
13% of 38 decks
-5% synergy
Path of Ancestry
13% of 38 decks
-8% synergy
Secluded Courtyard
11% of 37 decks
+6% synergy
Arid Mesa
8% of 38 decks
-3% synergy