Yawgmoth, Thran Physician + Nest of Scarabs + Falkenrath Noble Combo

All permanents on the battlefield.

Your life total is at least 2. You control at least one additional creature. There is at least one other creature on the battlefield.

Activate Yawgmoth by paying 1 life and sacrificing another creature.

When the creature dies, Falkenrath Noble triggers, causing you to gain 1 life and target opponent to lose 1 life.

Resolve the Yawgmoth ability, putting a -1/-1 counter on any other creature and causing you to draw a card.

If the creature who had the counter placed has 0 toughness, it dies as a state-based action.

Nest of Scarabs triggers, creating a 1/1 Insect creature token.

Repeat until your opponents do not control any more creatures, or until you draw your library.

If you have cards remaining in your library, you may repeat this combo any time a creature enters the battlefield under an opponent's control.

Destroy all creatures opponents control

Destroy each creature that enters the battlefield under an opponent's control

Lock

Significant -1/-1 counters

Significant card draw

Significant death triggers

Significant draw triggers

Significant creature ETB

Significant lifegain triggers

Significant creature LTB

Significant creature sacrifice triggers

Significant lifeloss