Razorkin Needlehead + Vilis, Broker of Blood + Fateful Handoff
Razorkin Needlehead
Vilis, Broker of Blood
Fateful Handoff
Requires
Razorkin Needlehead must be on the battlefield.
Vilis, Broker of Blood must be on the battlefield.
Fateful Handoff must be in hand.
Your deck size is at least nine.
Mana needed: 
Steps
- Cast Fateful Handoff by paying , causing you to draw eight cards and give control of Vilis to an opponent.
- During that opponent's draw step, they draw a card.
- Razorkin Needlehead triggers, dealing 1 damage to the opponent.
- Vilis triggers, causing the opponent to draw a card.
- Repeat from step 3 until the opponent loses the game either due to drawing from an empty library, or from having 0 life.
Results
Target opponent loses the game. Near-infinite damage to target opponent. Infinite card draw for target opponent. Infinite draw triggers for target opponent.
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+33% synergy
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+84% synergy
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Dimir Aqueduct
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Temple of Epiphany
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Crumbling Necropolis
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Sunken Hollow
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Command Tower
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Shadowblood Ridge
67% of 3 decks
+55% synergy
Rakdos Carnarium
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Dragonskull Summit
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Exotic Orchard
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+31% synergy
Tramway Station
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Spire of Industry
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Canyon Slough
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+27% synergy
Blightstep Pathway
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Tainted Peak
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Scalding Tarn
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Polluted Delta
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Temple of Malice
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Terramorphic Expanse
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Foreboding Ruins
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Evolving Wilds
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Path of Ancestry
33% of 3 decks
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Luxury Suite
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Smoldering Marsh
33% of 3 decks
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Blood Crypt
33% of 3 decks
-5% synergy