Nekusar, the Mindrazer + Echo of Eons + Triumph of the Hordes Combo

Echo of Eons in hand.

Nekusar and Triumph of the Hordes on the battlefield.

if each opponent has three or more poison counters, or otherwise available

Cast Triumph of the Hordes by paying , giving creatures you control +1/+1 and infect until end of turn.

Cast Echo of Eons by paying , causing each player to discard their hands and draw seven cards.

Nekusar triggers for each card your opponents draw.

Resolve the first trigger, causing the opponent to get a poison counter.

If the opponent has ten or more poison counters, they lose the game as a state-based action.

Repeat from step 4 for each remaining trigger.

If needed, cast Echo of Eons from your graveyard for its flashback cost by paying , causing each player to discard their hands and draw seven cards.

Repeat from step 3.

Each opponent loses the game