Hapatra, Vizier of Poisons (Commander) - Infect

Hapatra, Vizier of Poisons
Rank #413
214decks
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Background image for The Top 40 Two-Mana Commanders
Cooper Gottfried
Jan 12, 2026
Cooper Gottfried
The Top 40 Two-Mana Commanders
In this latest Top 40 list, Cooper dives into the most popular commanders on EDHREC that you can play for just two mana.
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Enchantments
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Utility Lands
Mana Artifacts
Lands
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Sinister Gnarlbark
23%inclusion3 decks13 decks
22%synergy
Dread Tiller
23%inclusion3 decks13 decks
22%synergy
Moonshadow
10%inclusion1 decks10 decks
10%synergy
Eventide's Shadow
7.7%inclusion1 decks13 decks
7%synergy
High Perfect Morcant
7.1%inclusion2 decks28 decks
6%synergy
High Synergy Cards
Fynn, the Fangbearer
79%inclusion170 decks214 decks
73%synergy
Nest of Scarabs
74%inclusion159 decks214 decks
73%synergy
Contagion Clasp
71%inclusion153 decks214 decks
69%synergy
Black Sun's Zenith
69%inclusion147 decks214 decks
66%synergy
Obelisk Spider
68%inclusion146 decks214 decks
65%synergy
Blowfly Infestation
65%inclusion140 decks214 decks
64%synergy
Grim Affliction
61%inclusion130 decks214 decks
59%synergy
Karn's Bastion
64%inclusion136 decks214 decks
58%synergy
Evolution Sage
64%inclusion136 decks214 decks
57%synergy
Necroskitter
55%inclusion118 decks214 decks
54%synergy
Top Cards
Contagion Engine
55%inclusion117 decks214 decks
53%synergy
Yawgmoth, Thran Physician
54%inclusion116 decks214 decks
47%synergy
Generous Patron
53%inclusion114 decks214 decks
52%synergy
Devoted Druid
53%inclusion114 decks214 decks
49%synergy
Skullclamp
51%inclusion109 decks214 decks
20%synergy
Persistent Constrictor
46%inclusion75 decks164 decks
44%synergy
Massacre Girl, Known Killer
45%inclusion96 decks214 decks
43%synergy
Hooded Blightfang
44%inclusion95 decks214 decks
41%synergy
Channeler Initiate
44%inclusion94 decks214 decks
43%synergy
Unnatural Restoration
43%inclusion93 decks214 decks
40%synergy
Game Changers
Demonic Tutor
13%inclusion27 decks214 decks
-3%synergy
Vampiric Tutor
10%inclusion21 decks214 decks
-1%synergy
Worldly Tutor
8.4%inclusion18 decks214 decks
-2%synergy
Gaea's Cradle
5.1%inclusion11 decks214 decks
0%synergy
Creatures
Cankerbloom
43%inclusion92 decks214 decks
29%synergy
Carnifex Demon
43%inclusion91 decks214 decks
41%synergy
Spitting Dilophosaurus
39%inclusion83 decks214 decks
38%synergy
Wickerbough Elder
38%inclusion81 decks214 decks
37%synergy
Zulaport Cutthroat
36%inclusion77 decks214 decks
15%synergy
Ammit Eternal
36%inclusion77 decks214 decks
35%synergy
Ichor Rats
35%inclusion75 decks214 decks
34%synergy
Viridian Corrupter
34%inclusion73 decks214 decks
33%synergy
Soul Snuffers
34%inclusion73 decks214 decks
33%synergy
Bloated Contaminator
34%inclusion73 decks214 decks
33%synergy
Ohran Frostfang
33%inclusion70 decks214 decks
25%synergy
Skithiryx, the Blight Dragon
32%inclusion68 decks214 decks
31%synergy
Plague Stinger
31%inclusion67 decks214 decks
30%synergy
Blood Artist
30%inclusion64 decks214 decks
10%synergy
Phyrexian Swarmlord
30%inclusion64 decks214 decks
29%synergy
Venerated Rotpriest
30%inclusion64 decks214 decks
29%synergy
Maha, Its Feathers Night
29%inclusion53 decks182 decks
27%synergy
Seshiro the Anointed
28%inclusion60 decks214 decks
26%synergy
Glistener Elf
27%inclusion58 decks214 decks
26%synergy
Contaminant Grafter
27%inclusion58 decks214 decks
26%synergy
Poison-Tip Archer
27%inclusion58 decks214 decks
9%synergy
Blight Mamba
27%inclusion57 decks214 decks
26%synergy
Core Prowler
26%inclusion55 decks214 decks
25%synergy
Phyrexian Hydra
26%inclusion55 decks214 decks
25%synergy
Dusk Urchins
25%inclusion54 decks214 decks
25%synergy
Plague Myr
25%inclusion53 decks214 decks
24%synergy
Skinrender
25%inclusion53 decks214 decks
24%synergy
Necropede
25%inclusion53 decks214 decks
24%synergy
Flesh-Eater Imp
24%inclusion52 decks214 decks
24%synergy
Banewhip Punisher
24%inclusion52 decks214 decks
24%synergy
Blightbelly Rat
23%inclusion50 decks214 decks
22%synergy
Saryth, the Viper's Fang
23%inclusion49 decks214 decks
20%synergy
Midnight Banshee
23%inclusion49 decks214 decks
22%synergy
Hand of the Praetors
23%inclusion49 decks214 decks
23%synergy
Plaguemaw Beast
21%inclusion45 decks214 decks
20%synergy
Quillspike
21%inclusion44 decks214 decks
20%synergy
Mirkwood Bats
20%inclusion43 decks214 decks
1%synergy
Phyrexian Crusader
20%inclusion43 decks214 decks
20%synergy
Ichorclaw Myr
19%inclusion40 decks214 decks
18%synergy
Fume Spitter
18%inclusion38 decks214 decks
17%synergy
Sakura-Tribe Elder
18%inclusion38 decks214 decks
-12%synergy
Decimator Beetle
17%inclusion37 decks214 decks
17%synergy
Aphelia, Viper Whisperer
17%inclusion25 decks150 decks
16%synergy
Rot Wolf
16%inclusion35 decks214 decks
16%synergy
Reaper of Sheoldred
16%inclusion34 decks214 decks
16%synergy
Birds of Paradise
16%inclusion34 decks214 decks
-5%synergy
Toski, Bearer of Secrets
15%inclusion33 decks214 decks
2%synergy
Eternal Witness
15%inclusion33 decks214 decks
-9%synergy
Whispering Specter
15%inclusion32 decks214 decks
15%synergy
Ivy Lane Denizen
15%inclusion32 decks214 decks
10%synergy
Instants
Assassin's Trophy
38%inclusion82 decks214 decks
-7%synergy
Infectious Bite
36%inclusion77 decks214 decks
34%synergy
Heroic Intervention
30%inclusion64 decks214 decks
0%synergy
Vraska's Fall
29%inclusion63 decks214 decks
28%synergy
Atomize
29%inclusion59 decks207 decks
24%synergy
Virulent Wound
28%inclusion60 decks214 decks
28%synergy
Beast Within
27%inclusion58 decks214 decks
-10%synergy
Putrefy
27%inclusion58 decks214 decks
-8%synergy
Splendid Agony
27%inclusion57 decks214 decks
26%synergy
Whisper of the Dross
26%inclusion55 decks214 decks
24%synergy
Golgari Charm
25%inclusion54 decks214 decks
8%synergy
Village Rites
22%inclusion47 decks214 decks
5%synergy
Revitalizing Repast
20%inclusion39 decks191 decks
1%synergy
Tainted Strike
17%inclusion37 decks214 decks
15%synergy
Abrupt Decay
14%inclusion29 decks214 decks
-3%synergy
Dark Ritual
13%inclusion28 decks214 decks
-4%synergy
Tear Asunder
12%inclusion25 decks214 decks
-3%synergy
Corrupted Conviction
12%inclusion25 decks214 decks
5%synergy
Deadly Dispute
12%inclusion25 decks214 decks
-8%synergy
Torment of Venom
11%inclusion23 decks214 decks
10%synergy
Hapatra's Mark
10%inclusion22 decks214 decks
10%synergy
Second Harvest
10%inclusion22 decks214 decks
-3%synergy
Sudden Spoiling
10%inclusion21 decks214 decks
9%synergy
Plumb the Forbidden
9.3%inclusion20 decks214 decks
1%synergy
Fell the Profane
8.9%inclusion17 decks191 decks
0%synergy
Chord of Calling
8.9%inclusion19 decks214 decks
4%synergy
Noxious Revival
8.9%inclusion19 decks214 decks
4%synergy
Nature's Claim
8.4%inclusion18 decks214 decks
-1%synergy
Deathsprout
7.9%inclusion17 decks214 decks
1%synergy
Invigorate
7.9%inclusion17 decks214 decks
7%synergy
Krosan Grip
7.5%inclusion16 decks214 decks
1%synergy
Snakeskin Veil
7.0%inclusion15 decks214 decks
-1%synergy
Return to Nature
6.5%inclusion14 decks214 decks
0%synergy
Malakir Rebirth
6.5%inclusion14 decks214 decks
-3%synergy
Khalni Ambush
6.1%inclusion13 decks214 decks
4%synergy
Stinging Shot
6.1%inclusion13 decks214 decks
6%synergy
Carrion Call
6.1%inclusion13 decks214 decks
6%synergy
Deadly Rollick
5.1%inclusion11 decks214 decks
-5%synergy
Murder
5.1%inclusion11 decks214 decks
1%synergy
Pistus Strike
5.1%inclusion11 decks214 decks
5%synergy
Tamiyo's Safekeeping
5.1%inclusion11 decks214 decks
-3%synergy
Sorceries
Infectious Inquiry
38%inclusion82 decks214 decks
37%synergy
Triumph of the Hordes
37%inclusion79 decks214 decks
32%synergy
Cultivate
37%inclusion79 decks214 decks
-3%synergy
Rampant Growth
29%inclusion63 decks214 decks
-5%synergy
Thirsting Roots
29%inclusion62 decks214 decks
27%synergy
Incremental Blight
29%inclusion61 decks214 decks
28%synergy
Smell Fear
27%inclusion58 decks214 decks
26%synergy
Drown in Ichor
27%inclusion58 decks214 decks
25%synergy
Phyresis Outbreak
22%inclusion48 decks214 decks
22%synergy
Kodama's Reach
21%inclusion46 decks214 decks
-3%synergy
Liliana's Influence
20%inclusion43 decks214 decks
20%synergy
Lethal Sting
19%inclusion41 decks214 decks
19%synergy
Nature's Lore
16%inclusion34 decks214 decks
-10%synergy
Diabolic Intent
14%inclusion31 decks214 decks
4%synergy
Persist
14%inclusion31 decks214 decks
12%synergy
Victimize
14%inclusion30 decks214 decks
-5%synergy
Toxic Deluge
13%inclusion28 decks214 decks
-8%synergy
Noxious Assault
13%inclusion28 decks214 decks
13%synergy
Spread the Sickness
12%inclusion26 decks214 decks
12%synergy
Expand the Sphere
12%inclusion25 decks214 decks
11%synergy
Farseek
12%inclusion25 decks214 decks
-7%synergy
Diabolic Tutor
11%inclusion23 decks214 decks
5%synergy
Bridgeworks Battle
9.4%inclusion18 decks191 decks
5%synergy
Bala Ged Recovery
9.3%inclusion20 decks214 decks
-2%synergy
Casualties of War
9.3%inclusion20 decks214 decks
-2%synergy
Planewide Celebration
9.3%inclusion20 decks214 decks
9%synergy
Vat Emergence
8.9%inclusion19 decks214 decks
8%synergy
Culling Ritual
8.9%inclusion19 decks214 decks
-12%synergy
Night's Whisper
8.4%inclusion18 decks214 decks
0%synergy
Three Visits
7.9%inclusion17 decks214 decks
-11%synergy
Caress of Phyrexia
7.9%inclusion17 decks214 decks
8%synergy
Sign in Blood
7.9%inclusion17 decks214 decks
1%synergy
Carnivorous Canopy
7.5%inclusion16 decks214 decks
7%synergy
Harvest Season
7.5%inclusion16 decks214 decks
4%synergy
Reanimate
7.0%inclusion15 decks214 decks
-13%synergy
Geth's Summons
7.0%inclusion15 decks214 decks
7%synergy
Overrun
7.0%inclusion15 decks214 decks
4%synergy
Courage in Crisis
7.0%inclusion15 decks214 decks
7%synergy
Read the Bones
7.0%inclusion15 decks214 decks
1%synergy
Harmonize
7.0%inclusion15 decks214 decks
-1%synergy
Shamanic Revelation
7.0%inclusion15 decks214 decks
-4%synergy
Feed the Infection
6.5%inclusion14 decks214 decks
6%synergy
Eldritch Evolution
6.1%inclusion13 decks214 decks
2%synergy
Damnation
6.1%inclusion13 decks214 decks
-2%synergy
Finale of Devastation
5.6%inclusion12 decks214 decks
-1%synergy
Driven // Despair
5.6%inclusion12 decks214 decks
5%synergy
Maelstrom Pulse
5.6%inclusion12 decks214 decks
0%synergy
Green Sun's Zenith
5.1%inclusion11 decks214 decks
-1%synergy
Viral Spawning
5.1%inclusion11 decks214 decks
5%synergy
Utility Artifacts
Whispersilk Cloak
33%inclusion71 decks214 decks
27%synergy
Swiftfoot Boots
21%inclusion44 decks214 decks
-4%synergy
Lightning Greaves
19%inclusion40 decks214 decks
-3%synergy
Viridian Longbow
18%inclusion39 decks214 decks
14%synergy
Serrated Arrows
12%inclusion26 decks214 decks
12%synergy
Ashnod's Altar
12%inclusion25 decks214 decks
-8%synergy
Cauldron of Souls
11%inclusion24 decks214 decks
11%synergy
Phyrexian Altar
10%inclusion22 decks214 decks
1%synergy
Grafted Exoskeleton
10%inclusion21 decks214 decks
9%synergy
Sword of Truth and Justice
8.9%inclusion19 decks214 decks
8%synergy
Bow of Nylea
7.5%inclusion16 decks214 decks
4%synergy
Trigon of Corruption
7.0%inclusion15 decks214 decks
7%synergy
Eldrazi Monument
6.5%inclusion14 decks214 decks
4%synergy
Decimator Web
6.1%inclusion13 decks214 decks
6%synergy
Trailblazer's Boots
6.1%inclusion13 decks214 decks
3%synergy
Enchantments
Crumbling Ashes
37%inclusion80 decks214 decks
36%synergy
Flourishing Defenses
33%inclusion70 decks214 decks
31%synergy
Moldervine Reclamation
30%inclusion64 decks214 decks
6%synergy
Beastmaster Ascension
27%inclusion57 decks214 decks
15%synergy
Cryptolith Rite
23%inclusion49 decks214 decks
18%synergy
Parallel Lives
23%inclusion49 decks214 decks
10%synergy
Deathreap Ritual
20%inclusion42 decks214 decks
8%synergy
Glistening Oil
17%inclusion37 decks214 decks
17%synergy
Growing Rites of Itlimoc
15%inclusion33 decks214 decks
6%synergy
Phyrexian Arena
15%inclusion33 decks214 decks
2%synergy
Phyresis
13%inclusion27 decks214 decks
11%synergy
Bastion of Remembrance
11%inclusion24 decks214 decks
-2%synergy
Necrogen Communion
11%inclusion24 decks214 decks
10%synergy
Doubling Season
11%inclusion23 decks214 decks
-6%synergy
Wild Growth
10%inclusion21 decks214 decks
0%synergy
Vraska Joins Up
9.4%inclusion19 decks203 decks
4%synergy
Insidious Roots
9.3%inclusion20 decks214 decks
-2%synergy
Phyrexian Reclamation
6.5%inclusion14 decks214 decks
3%synergy
Journey to Eternity
6.5%inclusion14 decks214 decks
1%synergy
The Meathook Massacre
6.5%inclusion14 decks214 decks
-2%synergy
Grave Pact
6.1%inclusion13 decks214 decks
-2%synergy
Cultist of the Absolute
6.1%inclusion13 decks214 decks
4%synergy
Rancor
5.6%inclusion12 decks214 decks
0%synergy
Sadistic Obsession
5.1%inclusion11 decks214 decks
5%synergy
Canopy Cover
5.1%inclusion11 decks214 decks
4%synergy
Sylvan Library
5.1%inclusion11 decks214 decks
-4%synergy
Planeswalkers
Vraska, Betrayal's Sting
30%inclusion64 decks214 decks
27%synergy
Liliana, Death Wielder
19%inclusion40 decks214 decks
18%synergy
Vraska, Golgari Queen
14%inclusion29 decks214 decks
7%synergy
Vraska, Swarm's Eminence
7.5%inclusion16 decks214 decks
6%synergy
Vraska the Unseen
5.1%inclusion11 decks214 decks
3%synergy
Utility Lands
Rogue's Passage
44%inclusion95 decks214 decks
20%synergy
Bojuka Bog
36%inclusion78 decks214 decks
-4%synergy
Grasping Dunes
29%inclusion61 decks214 decks
28%synergy
Ifnir Deadlands
23%inclusion49 decks214 decks
22%synergy
Nesting Grounds
22%inclusion48 decks214 decks
20%synergy
Inkmoth Nexus
18%inclusion38 decks214 decks
17%synergy
Urborg, Tomb of Yawgmoth
17%inclusion37 decks214 decks
-6%synergy
Access Tunnel
17%inclusion36 decks214 decks
15%synergy
Reliquary Tower
15%inclusion33 decks214 decks
-8%synergy
Boseiju, Who Endures
15%inclusion32 decks214 decks
-3%synergy
Oran-Rief, the Vastwood
14%inclusion31 decks214 decks
4%synergy
Yavimaya, Cradle of Growth
14%inclusion30 decks214 decks
-14%synergy
Shizo, Death's Storehouse
14%inclusion29 decks214 decks
8%synergy
Phyrexian Tower
12%inclusion25 decks214 decks
-3%synergy
Hissing Quagmire
11%inclusion23 decks214 decks
7%synergy
Grim Backwoods
10%inclusion22 decks214 decks
-3%synergy
Cabal Coffers
9.3%inclusion20 decks214 decks
0%synergy
Desert of the Indomitable
7.9%inclusion17 decks214 decks
7%synergy
Temple of the False God
7.0%inclusion15 decks214 decks
0%synergy
Takenuma, Abandoned Mire
7.0%inclusion15 decks214 decks
-5%synergy
Westvale Abbey
6.1%inclusion13 decks214 decks
3%synergy
Castle Locthwain
5.6%inclusion12 decks214 decks
2%synergy
Mana Artifacts
Sol Ring
77%inclusion164 decks214 decks
-3%synergy
Arcane Signet
63%inclusion134 decks214 decks
0%synergy
Golgari Signet
32%inclusion69 decks214 decks
5%synergy
Talisman of Resilience
23%inclusion49 decks214 decks
-2%synergy
Glistening Sphere
21%inclusion45 decks214 decks
20%synergy
Staff of Compleation
9.3%inclusion20 decks214 decks
8%synergy
Commander's Sphere
7.9%inclusion17 decks214 decks
0%synergy
Everflowing Chalice
7.0%inclusion15 decks214 decks
6%synergy
Phyrexian Atlas
5.6%inclusion12 decks214 decks
5%synergy
Lands
Forest
99%inclusion211 decks214 decks
1%synergy
Swamp
98%inclusion210 decks214 decks
1%synergy
Command Tower
80%inclusion171 decks214 decks
-6%synergy
Woodland Cemetery
59%inclusion127 decks214 decks
-2%synergy
Llanowar Wastes
51%inclusion109 decks214 decks
-1%synergy
Overgrown Tomb
47%inclusion101 decks214 decks
2%synergy
Tainted Wood
43%inclusion93 decks214 decks
-1%synergy
Golgari Rot Farm
39%inclusion83 decks214 decks
-3%synergy
Undergrowth Stadium
38%inclusion81 decks214 decks
-1%synergy
Twilight Mire
36%inclusion77 decks214 decks
0%synergy
Necroblossom Snarl
35%inclusion74 decks214 decks
-1%synergy
Temple of Malady
33%inclusion70 decks214 decks
-2%synergy
Deathcap Glade
32%inclusion69 decks214 decks
3%synergy
Verdant Catacombs
32%inclusion68 decks214 decks
2%synergy
Jungle Hollow
29%inclusion61 decks214 decks
4%synergy
Evolving Wilds
28%inclusion59 decks214 decks
0%synergy
Darkbore Pathway
24%inclusion51 decks214 decks
4%synergy
Blooming Marsh
22%inclusion47 decks214 decks
8%synergy
Wastewood Verge
21%inclusion28 decks133 decks
4%synergy
Viridescent Bog
21%inclusion43 decks207 decks
0%synergy
Terramorphic Expanse
21%inclusion44 decks214 decks
0%synergy
Revitalizing Repast
20%inclusion39 decks191 decks
1%synergy
Exotic Orchard
20%inclusion42 decks214 decks
-8%synergy
Underground Mortuary
15%inclusion33 decks214 decks
-5%synergy
Golgari Guildgate
15%inclusion33 decks214 decks
6%synergy
Nurturing Peatland
14%inclusion31 decks214 decks
2%synergy
Foul Orchard
14%inclusion30 decks214 decks
9%synergy
Vernal Fen
12%inclusion10 decks82 decks
1%synergy
Festering Thicket
12%inclusion10 decks82 decks
7%synergy
Haunted Mire
12%inclusion26 decks214 decks
-4%synergy
Bayou
11%inclusion23 decks214 decks
-1%synergy
Myriad Landscape
10%inclusion22 decks214 decks
-6%synergy
Bridgeworks Battle
9.4%inclusion18 decks191 decks
5%synergy
Bala Ged Recovery
9.3%inclusion20 decks214 decks
-2%synergy
Fell the Profane
8.9%inclusion17 decks191 decks
0%synergy
Fabled Passage
6.5%inclusion14 decks214 decks
-7%synergy
Malakir Rebirth
6.5%inclusion14 decks214 decks
-3%synergy
Blighted Woodland
6.1%inclusion13 decks214 decks
1%synergy
Khalni Ambush
6.1%inclusion13 decks214 decks
4%synergy
Festering Gulch
5.9%inclusion12 decks204 decks
1%synergy
Opal Palace
5.6%inclusion12 decks214 decks
3%synergy
Woodland Chasm
5.6%inclusion12 decks214 decks
-2%synergy
Forbidden Orchard
5.6%inclusion12 decks214 decks
4%synergy
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