Omnath, Locus of All (Commander) - Infect

Omnath, Locus of All
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Atraxa, Praetors' Voice
62%inclusion93 decks151 decks
59%synergy
Ixhel, Scion of Atraxa
58%inclusion88 decks151 decks
58%synergy
Urabrask the Hidden
58%inclusion87 decks151 decks
56%synergy
Elesh Norn
56%inclusion84 decks151 decks
55%synergy
Prologue to Phyresis
54%inclusion82 decks151 decks
54%synergy
Realmbreaker, the Invasion Tree
53%inclusion80 decks151 decks
52%synergy
Vraska, Betrayal's Sting
52%inclusion79 decks151 decks
51%synergy
Brimaz, Blight of Oreskos
50%inclusion76 decks151 decks
50%synergy
Vishgraz, the Doomhive
50%inclusion75 decks151 decks
50%synergy
Vraska's Fall
49%inclusion74 decks151 decks
49%synergy
Top Cards
Thrummingbird
49%inclusion74 decks151 decks
48%synergy
Venerated Rotpriest
49%inclusion74 decks151 decks
49%synergy
White Sun's Twilight
48%inclusion73 decks151 decks
48%synergy
Skrelv, Defector Mite
48%inclusion73 decks151 decks
46%synergy
Tekuthal, Inquiry Dominus
48%inclusion73 decks151 decks
47%synergy
Vorinclex, Monstrous Raider
48%inclusion73 decks151 decks
46%synergy
Bloated Contaminator
47%inclusion71 decks151 decks
47%synergy
Phyrexian Censor
46%inclusion70 decks151 decks
46%synergy
Jin-Gitaxias
46%inclusion70 decks151 decks
44%synergy
Elesh Norn, Grand Cenobite
46%inclusion69 decks151 decks
43%synergy
Game Changers
Smothering Tithe
14%inclusion21 decks151 decks
-5%synergy
Rhystic Study
12%inclusion18 decks151 decks
-9%synergy
Cyclonic Rift
12%inclusion18 decks151 decks
-5%synergy
Demonic Tutor
11%inclusion16 decks151 decks
-8%synergy
Vampiric Tutor
10%inclusion15 decks151 decks
-4%synergy
Enlightened Tutor
7.9%inclusion12 decks151 decks
-6%synergy
Teferi's Protection
6.6%inclusion10 decks151 decks
-9%synergy
Mystical Tutor
5.3%inclusion8 decks151 decks
-1%synergy
Creatures
Cankerbloom
46%inclusion69 decks151 decks
45%synergy
Sheoldred, Whispering One
44%inclusion67 decks151 decks
43%synergy
Sheoldred
44%inclusion67 decks151 decks
43%synergy
Atraxa, Grand Unifier
44%inclusion66 decks151 decks
40%synergy
Glissa, Herald of Predation
42%inclusion63 decks151 decks
41%synergy
Ezuri, Stalker of Spheres
41%inclusion62 decks151 decks
41%synergy
Vorinclex, Voice of Hunger
41%inclusion62 decks151 decks
39%synergy
Elesh Norn, Mother of Machines
39%inclusion59 decks151 decks
37%synergy
Jin-Gitaxias, Core Augur
37%inclusion56 decks151 decks
35%synergy
Jin-Gitaxias, Progress Tyrant
36%inclusion54 decks151 decks
34%synergy
Vorinclex
35%inclusion53 decks151 decks
34%synergy
Tyrranax Rex
34%inclusion52 decks151 decks
34%synergy
Tainted Observer
34%inclusion52 decks151 decks
34%synergy
Contaminant Grafter
34%inclusion52 decks151 decks
34%synergy
Phyrexian Obliterator
34%inclusion51 decks151 decks
33%synergy
Sheoldred, the Apocalypse
32%inclusion49 decks151 decks
31%synergy
Necrogen Rotpriest
30%inclusion45 decks151 decks
30%synergy
Blightbelly Rat
30%inclusion45 decks151 decks
30%synergy
Zopandrel, Hunger Dominus
30%inclusion45 decks151 decks
29%synergy
Phyrexian Vindicator
29%inclusion44 decks151 decks
29%synergy
Grafted Butcher
29%inclusion44 decks151 decks
29%synergy
Etali, Primal Conqueror
27%inclusion41 decks151 decks
25%synergy
Skithiryx, the Blight Dragon
27%inclusion41 decks151 decks
26%synergy
Metastatic Evangel
27%inclusion28 decks105 decks
26%synergy
Essence of Orthodoxy
25%inclusion37 decks151 decks
24%synergy
Mondrak, Glory Dominus
25%inclusion37 decks151 decks
23%synergy
Blighted Agent
23%inclusion35 decks151 decks
23%synergy
Myr Convert
23%inclusion34 decks151 decks
20%synergy
Phyrexian Swarmlord
23%inclusion34 decks151 decks
22%synergy
Gix, Yawgmoth Praetor
22%inclusion33 decks151 decks
21%synergy
Blightsteel Colossus
22%inclusion33 decks151 decks
21%synergy
Armored Scrapgorger
21%inclusion32 decks151 decks
21%synergy
Urabrask, Heretic Praetor
21%inclusion32 decks151 decks
21%synergy
Urabrask
21%inclusion31 decks151 decks
20%synergy
Glissa Sunslayer
20%inclusion30 decks151 decks
18%synergy
Venser, Corpse Puppet
19%inclusion29 decks151 decks
19%synergy
Voidwing Hybrid
19%inclusion28 decks151 decks
18%synergy
Slaughter Singer
18%inclusion27 decks151 decks
18%synergy
Bilious Skulldweller
18%inclusion27 decks151 decks
18%synergy
Ria Ivor, Bane of Bladehold
18%inclusion27 decks151 decks
18%synergy
Massacre Wurm
17%inclusion26 decks151 decks
17%synergy
Ichor Rats
17%inclusion26 decks151 decks
17%synergy
Venomous Brutalizer
17%inclusion25 decks151 decks
17%synergy
Mishra, Claimed by Gix
16%inclusion24 decks151 decks
16%synergy
Phyrexian Dragon Engine
15%inclusion23 decks151 decks
15%synergy
Soul of New Phyrexia
15%inclusion23 decks151 decks
15%synergy
Paladin of Predation
14%inclusion21 decks151 decks
14%synergy
Evolution Sage
13%inclusion20 decks151 decks
12%synergy
Norn's Choirmaster
13%inclusion20 decks151 decks
13%synergy
Progenitor Exarch
13%inclusion19 decks151 decks
12%synergy
Instants
Infectious Bite
35%inclusion53 decks151 decks
35%synergy
Swords to Plowshares
30%inclusion45 decks151 decks
-10%synergy
Experimental Augury
26%inclusion40 decks151 decks
25%synergy
Black Sun's Twilight
25%inclusion38 decks151 decks
25%synergy
Reject Imperfection
25%inclusion37 decks151 decks
24%synergy
Path to Exile
21%inclusion32 decks151 decks
-6%synergy
Counterspell
16%inclusion24 decks151 decks
-7%synergy
Void Rend
13%inclusion19 decks151 decks
9%synergy
Negate
13%inclusion19 decks151 decks
4%synergy
Whisper of the Dross
11%inclusion16 decks151 decks
10%synergy
Tainted Strike
11%inclusion16 decks151 decks
10%synergy
Bring the Ending
11%inclusion16 decks151 decks
11%synergy
Heroic Intervention
10%inclusion15 decks151 decks
-13%synergy
Beast Within
10%inclusion15 decks151 decks
-3%synergy
Noxious Revival
10%inclusion15 decks151 decks
8%synergy
Serum Snare
10%inclusion15 decks151 decks
10%synergy
Volt Charge
9.3%inclusion14 decks151 decks
9%synergy
Fuel for the Cause
7.9%inclusion12 decks151 decks
8%synergy
Mana Drain
7.9%inclusion12 decks151 decks
-1%synergy
Charge of the Mites
7.9%inclusion12 decks151 decks
8%synergy
Atomize
7.6%inclusion10 decks131 decks
7%synergy
Dark Ritual
7.3%inclusion11 decks151 decks
2%synergy
Radstorm
7.3%inclusion11 decks151 decks
7%synergy
Sheoldred's Edict
6.6%inclusion10 decks151 decks
6%synergy
Corrupted Resolve
6.0%inclusion9 decks151 decks
6%synergy
Offer Immortality
6.0%inclusion9 decks151 decks
6%synergy
Assassin's Trophy
5.3%inclusion8 decks151 decks
-8%synergy
Brokers Confluence
5.3%inclusion8 decks151 decks
5%synergy
Mortify
5.3%inclusion8 decks151 decks
2%synergy
Dismember
5.3%inclusion8 decks151 decks
4%synergy
Sorceries
Infectious Inquiry
38%inclusion58 decks151 decks
38%synergy
Phyresis Outbreak
35%inclusion53 decks151 decks
35%synergy
Unnatural Restoration
32%inclusion48 decks151 decks
31%synergy
Farseek
28%inclusion43 decks151 decks
-15%synergy
Drown in Ichor
27%inclusion41 decks151 decks
27%synergy
Cultivate
25%inclusion38 decks151 decks
-9%synergy
Expand the Sphere
24%inclusion36 decks151 decks
24%synergy
Thirsting Roots
23%inclusion35 decks151 decks
23%synergy
Sunfall
23%inclusion35 decks151 decks
23%synergy
Tezzeret's Gambit
21%inclusion32 decks151 decks
20%synergy
Green Sun's Twilight
21%inclusion31 decks151 decks
20%synergy
Breach the Multiverse
21%inclusion31 decks151 decks
20%synergy
Triumph of the Hordes
19%inclusion28 decks151 decks
18%synergy
Blue Sun's Twilight
15%inclusion23 decks151 decks
15%synergy
Kodama's Reach
15%inclusion22 decks151 decks
-7%synergy
Red Sun's Twilight
15%inclusion22 decks151 decks
14%synergy
Phyrexian Rebirth
15%inclusion22 decks151 decks
14%synergy
Vat Emergence
14%inclusion21 decks151 decks
14%synergy
Nature's Lore
13%inclusion20 decks151 decks
-13%synergy
Rampant Growth
13%inclusion20 decks151 decks
-7%synergy
Three Visits
12%inclusion18 decks151 decks
-11%synergy
Noxious Assault
11%inclusion17 decks151 decks
11%synergy
Glistening Dawn
11%inclusion16 decks151 decks
11%synergy
Feed the Infection
9.3%inclusion14 decks151 decks
9%synergy
Distorted Curiosity
9.3%inclusion14 decks151 decks
9%synergy
Caress of Phyrexia
9.3%inclusion14 decks151 decks
9%synergy
Vivisurgeon's Insight
8.6%inclusion13 decks151 decks
8%synergy
Geth's Summons
7.9%inclusion12 decks151 decks
8%synergy
Kindred Dominance
7.3%inclusion11 decks151 decks
2%synergy
Ruinous Ultimatum
7.3%inclusion11 decks151 decks
0%synergy
Praetor's Counsel
6.6%inclusion10 decks151 decks
6%synergy
Wurmquake
6.0%inclusion9 decks151 decks
6%synergy
Praetor's Grasp
6.0%inclusion9 decks151 decks
6%synergy
Sunder the Gateway
6.0%inclusion9 decks151 decks
6%synergy
Eerie Ultimatum
5.3%inclusion8 decks151 decks
-2%synergy
Blasphemous Act
5.3%inclusion8 decks151 decks
-5%synergy
Carnivorous Canopy
5.3%inclusion8 decks151 decks
5%synergy
Utility Artifacts
Portal to Phyrexia
26%inclusion40 decks151 decks
26%synergy
Monument to Perfection
25%inclusion38 decks151 decks
25%synergy
Norn's Annex
19%inclusion28 decks151 decks
18%synergy
Urabrask's Forge
16%inclusion24 decks151 decks
16%synergy
Contagion Engine
15%inclusion23 decks151 decks
15%synergy
Herald's Horn
15%inclusion23 decks151 decks
-3%synergy
Urza's Incubator
13%inclusion20 decks151 decks
-1%synergy
Lightning Greaves
13%inclusion19 decks151 decks
-5%synergy
Ichormoon Gauntlet
11%inclusion17 decks151 decks
10%synergy
Infested Fleshcutter
10%inclusion15 decks151 decks
10%synergy
Contagion Clasp
9.3%inclusion14 decks151 decks
9%synergy
Conduit of Worlds
9.3%inclusion14 decks151 decks
8%synergy
Banner of Kinship
8.7%inclusion6 decks69 decks
6%synergy
Vanquisher's Banner
7.3%inclusion11 decks151 decks
0%synergy
Bitterthorn, Nissa's Animus
6.6%inclusion10 decks151 decks
6%synergy
Grafted Exoskeleton
6.6%inclusion10 decks151 decks
7%synergy
Jeskai Monument
6.1%inclusion2 decks33 decks
6%synergy
Abzan Monument
6.1%inclusion2 decks33 decks
6%synergy
Vat of Rebirth
6.0%inclusion9 decks151 decks
6%synergy
Doubling Cube
6.0%inclusion9 decks151 decks
5%synergy
Phyrexian Altar
5.3%inclusion8 decks151 decks
4%synergy
Swiftfoot Boots
5.3%inclusion8 decks151 decks
-7%synergy
Enchantments
Skrelv's Hive
44%inclusion67 decks151 decks
44%synergy
Norn's Decree
36%inclusion55 decks151 decks
36%synergy
Phyrexian Arena
33%inclusion50 decks151 decks
31%synergy
Phyrexian Awakening
31%inclusion47 decks151 decks
31%synergy
All Will Be One
28%inclusion43 decks151 decks
27%synergy
Inexorable Tide
25%inclusion37 decks151 decks
23%synergy
Tangled Skyline
21%inclusion31 decks151 decks
20%synergy
Leyline of the Guildpact
18%inclusion26 decks142 decks
3%synergy
Necrogen Communion
18%inclusion27 decks151 decks
18%synergy
Sculpted Perfection
15%inclusion23 decks151 decks
15%synergy
Phyresis
12%inclusion18 decks151 decks
12%synergy
Phyrexian Unlife
11%inclusion17 decks151 decks
11%synergy
Blighted Burgeoning
10%inclusion15 decks151 decks
10%synergy
Gift of Compleation
10%inclusion15 decks151 decks
10%synergy
Goliath Hatchery
9.3%inclusion14 decks151 decks
9%synergy
Corrupted Conscience
8.6%inclusion13 decks151 decks
9%synergy
Glistening Oil
8.6%inclusion13 decks151 decks
9%synergy
Kindred Discovery
6.6%inclusion10 decks151 decks
-5%synergy
Phyrexian Reclamation
6.6%inclusion10 decks151 decks
6%synergy
Corruption of Towashi
6.0%inclusion9 decks151 decks
6%synergy
Battles
Invasion of Alara
6.0%inclusion9 decks151 decks
4%synergy
Planeswalkers
Ajani, Sleeper Agent
23%inclusion34 decks151 decks
22%synergy
Nissa, Ascended Animist
22%inclusion33 decks151 decks
21%synergy
Lukka, Bound to Ruin
19%inclusion29 decks151 decks
19%synergy
Tamiyo, Compleated Sage
13%inclusion19 decks151 decks
12%synergy
Jace, the Perfected Mind
11%inclusion16 decks151 decks
10%synergy
Nahiri, the Unforgiving
7.9%inclusion12 decks151 decks
8%synergy
Wrenn and Realmbreaker
7.3%inclusion11 decks151 decks
5%synergy
Utility Lands
Karn's Bastion
42%inclusion63 decks151 decks
38%synergy
Reliquary Tower
26%inclusion40 decks151 decks
0%synergy
The Dross Pits
25%inclusion37 decks151 decks
24%synergy
The Fair Basilica
25%inclusion37 decks151 decks
24%synergy
The Hunter Maze
25%inclusion37 decks151 decks
24%synergy
The Surgical Bay
23%inclusion35 decks151 decks
23%synergy
The Autonomous Furnace
23%inclusion34 decks151 decks
22%synergy
The Monumental Facade
15%inclusion23 decks151 decks
15%synergy
Inkmoth Nexus
12%inclusion18 decks151 decks
12%synergy
Three Tree City
12%inclusion11 decks95 decks
4%synergy
Rogue's Passage
11%inclusion17 decks151 decks
5%synergy
Bojuka Bog
9.3%inclusion14 decks151 decks
5%synergy
Cascading Cataracts
9.3%inclusion14 decks151 decks
-7%synergy
Boseiju, Who Endures
7.3%inclusion11 decks151 decks
-4%synergy
Mistrise Village
6.1%inclusion2 decks33 decks
2%synergy
Urborg, Tomb of Yawgmoth
6.0%inclusion9 decks151 decks
-1%synergy
Phyrexian Tower
5.3%inclusion8 decks151 decks
4%synergy
Mana Artifacts
Sol Ring
77%inclusion116 decks151 decks
-2%synergy
Arcane Signet
66%inclusion100 decks151 decks
-9%synergy
Glistening Sphere
58%inclusion88 decks151 decks
58%synergy
Chromatic Lantern
52%inclusion78 decks151 decks
1%synergy
Phyrexian Atlas
47%inclusion71 decks151 decks
47%synergy
Fellwar Stone
25%inclusion37 decks151 decks
-6%synergy
Staff of Compleation
19%inclusion29 decks151 decks
19%synergy
Commander's Sphere
17%inclusion26 decks151 decks
0%synergy
Chromatic Orrery
12%inclusion18 decks151 decks
2%synergy
Replicating Ring
11%inclusion17 decks151 decks
10%synergy
Everflowing Chalice
11%inclusion17 decks151 decks
8%synergy
Patchwork Banner
11%inclusion10 decks93 decks
4%synergy
Tablet of Compleation
8.6%inclusion13 decks151 decks
9%synergy
Astral Cornucopia
7.9%inclusion12 decks151 decks
7%synergy
Timeless Lotus
6.6%inclusion10 decks151 decks
-3%synergy
Thought Vessel
6.0%inclusion9 decks151 decks
-1%synergy
Lands
Forest
92%inclusion139 decks151 decks
12%synergy
Swamp
91%inclusion138 decks151 decks
17%synergy
Plains
91%inclusion137 decks151 decks
14%synergy
Island
90%inclusion136 decks151 decks
12%synergy
Mountain
89%inclusion134 decks151 decks
13%synergy
Command Tower
83%inclusion125 decks151 decks
-5%synergy
The Seedcore
66%inclusion100 decks151 decks
66%synergy
Exotic Orchard
50%inclusion75 decks151 decks
-12%synergy
Path of Ancestry
50%inclusion75 decks151 decks
7%synergy
Mirrex
28%inclusion42 decks151 decks
28%synergy
The World Tree
26%inclusion39 decks151 decks
-3%synergy
Breeding Pool
25%inclusion38 decks151 decks
-5%synergy
Hallowed Fountain
25%inclusion38 decks151 decks
0%synergy
Overgrown Tomb
25%inclusion37 decks151 decks
-3%synergy
Temple Garden
25%inclusion37 decks151 decks
-4%synergy
Misty Rainforest
24%inclusion36 decks151 decks
-3%synergy
Indatha Triome
24%inclusion36 decks151 decks
2%synergy
The Mycosynth Gardens
22%inclusion33 decks151 decks
20%synergy
Stomping Ground
22%inclusion33 decks151 decks
-7%synergy
Marsh Flats
21%inclusion32 decks151 decks
-2%synergy
Watery Grave
21%inclusion32 decks151 decks
-3%synergy
Ketria Triome
21%inclusion32 decks151 decks
-3%synergy
Evolving Wilds
21%inclusion32 decks151 decks
1%synergy
Windswept Heath
21%inclusion31 decks151 decks
-7%synergy
Sandsteppe Citadel
21%inclusion31 decks151 decks
5%synergy
Opulent Palace
21%inclusion31 decks151 decks
5%synergy
Terramorphic Expanse
21%inclusion31 decks151 decks
5%synergy
Polluted Delta
19%inclusion29 decks151 decks
-4%synergy
Zagoth Triome
19%inclusion29 decks151 decks
-2%synergy
Spara's Headquarters
19%inclusion28 decks151 decks
-2%synergy
Verdant Catacombs
19%inclusion28 decks151 decks
-7%synergy
Savai Triome
18%inclusion27 decks151 decks
2%synergy
Godless Shrine
18%inclusion27 decks151 decks
-7%synergy
Steam Vents
17%inclusion26 decks151 decks
-6%synergy
Unclaimed Territory
17%inclusion26 decks151 decks
0%synergy
Arcane Sanctum
17%inclusion26 decks151 decks
5%synergy
Jetmir's Garden
17%inclusion26 decks151 decks
-3%synergy
Seaside Citadel
17%inclusion25 decks151 decks
2%synergy
Raffine's Tower
17%inclusion25 decks151 decks
3%synergy
Raugrin Triome
17%inclusion25 decks151 decks
-1%synergy
Arid Mesa
17%inclusion25 decks151 decks
-6%synergy
Cavern of Souls
16%inclusion24 decks151 decks
-1%synergy
Scalding Tarn
16%inclusion24 decks151 decks
-7%synergy
Jungle Shrine
16%inclusion24 decks151 decks
-1%synergy
Flooded Strand
16%inclusion24 decks151 decks
-9%synergy
Bloodstained Mire
16%inclusion24 decks151 decks
-6%synergy
Crumbling Necropolis
15%inclusion23 decks151 decks
4%synergy
Wooded Foothills
15%inclusion23 decks151 decks
-11%synergy
Razorverge Thicket
15%inclusion22 decks151 decks
13%synergy
Sacred Foundry
14%inclusion21 decks151 decks
-9%synergy
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