Omnath, Locus of All (Commander) - Infect

Omnath, Locus of All
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Urabrask the Hidden
59%inclusion82 decks140 decks
57%synergy
Atraxa, Praetors' Voice
60%inclusion84 decks140 decks
57%synergy
Ixhel, Scion of Atraxa
57%inclusion80 decks140 decks
57%synergy
Prologue to Phyresis
54%inclusion76 decks140 decks
54%synergy
Elesh Norn
55%inclusion77 decks140 decks
54%synergy
Realmbreaker, the Invasion Tree
54%inclusion75 decks140 decks
52%synergy
Brimaz, Blight of Oreskos
52%inclusion73 decks140 decks
52%synergy
Vishgraz, the Doomhive
50%inclusion70 decks140 decks
50%synergy
Vraska, Betrayal's Sting
51%inclusion71 decks140 decks
49%synergy
Vraska's Fall
49%inclusion68 decks140 decks
48%synergy
Top Cards
Vorinclex, Monstrous Raider
49%inclusion69 decks140 decks
47%synergy
Thrummingbird
49%inclusion68 decks140 decks
48%synergy
White Sun's Twilight
47%inclusion66 decks140 decks
47%synergy
Tekuthal, Inquiry Dominus
47%inclusion66 decks140 decks
46%synergy
Jin-Gitaxias
47%inclusion66 decks140 decks
45%synergy
Skrelv, Defector Mite
46%inclusion65 decks140 decks
44%synergy
Elesh Norn, Grand Cenobite
46%inclusion65 decks140 decks
44%synergy
Bloated Contaminator
46%inclusion65 decks140 decks
46%synergy
Venerated Rotpriest
46%inclusion65 decks140 decks
46%synergy
Phyrexian Censor
45%inclusion63 decks140 decks
45%synergy
Game Changers
Smothering Tithe
14%inclusion20 decks140 decks
-5%synergy
Rhystic Study
12%inclusion17 decks140 decks
-9%synergy
Cyclonic Rift
12%inclusion17 decks140 decks
-5%synergy
Vampiric Tutor
11%inclusion15 decks140 decks
-3%synergy
Demonic Tutor
10%inclusion14 decks140 decks
-9%synergy
Enlightened Tutor
8.6%inclusion12 decks140 decks
-6%synergy
Teferi's Protection
6.4%inclusion9 decks140 decks
-9%synergy
Mystical Tutor
5.7%inclusion8 decks140 decks
0%synergy
Seedborn Muse
5.0%inclusion7 decks140 decks
1%synergy
Fierce Guardianship
5.0%inclusion7 decks140 decks
-7%synergy
Creatures
Sheoldred, Whispering One
45%inclusion63 decks140 decks
43%synergy
Cankerbloom
44%inclusion62 decks140 decks
44%synergy
Glissa, Herald of Predation
44%inclusion61 decks140 decks
43%synergy
Sheoldred
44%inclusion61 decks140 decks
42%synergy
Atraxa, Grand Unifier
42%inclusion59 decks140 decks
39%synergy
Ezuri, Stalker of Spheres
41%inclusion57 decks140 decks
40%synergy
Vorinclex, Voice of Hunger
41%inclusion57 decks140 decks
39%synergy
Elesh Norn, Mother of Machines
40%inclusion56 decks140 decks
38%synergy
Jin-Gitaxias, Core Augur
37%inclusion52 decks140 decks
35%synergy
Jin-Gitaxias, Progress Tyrant
36%inclusion51 decks140 decks
35%synergy
Vorinclex
36%inclusion50 decks140 decks
35%synergy
Contaminant Grafter
35%inclusion49 decks140 decks
35%synergy
Tyrranax Rex
34%inclusion48 decks140 decks
34%synergy
Phyrexian Obliterator
34%inclusion47 decks140 decks
33%synergy
Sheoldred, the Apocalypse
34%inclusion47 decks140 decks
32%synergy
Tainted Observer
33%inclusion46 decks140 decks
33%synergy
Zopandrel, Hunger Dominus
31%inclusion43 decks140 decks
30%synergy
Phyrexian Vindicator
30%inclusion42 decks140 decks
30%synergy
Blightbelly Rat
30%inclusion42 decks140 decks
30%synergy
Necrogen Rotpriest
30%inclusion42 decks140 decks
30%synergy
Grafted Butcher
29%inclusion40 decks140 decks
28%synergy
Etali, Primal Conqueror
28%inclusion39 decks140 decks
25%synergy
Metastatic Evangel
27%inclusion27 decks100 decks
27%synergy
Mondrak, Glory Dominus
26%inclusion37 decks140 decks
25%synergy
Skithiryx, the Blight Dragon
26%inclusion36 decks140 decks
25%synergy
Essence of Orthodoxy
24%inclusion34 decks140 decks
24%synergy
Urabrask, Heretic Praetor
22%inclusion31 decks140 decks
22%synergy
Blightsteel Colossus
22%inclusion31 decks140 decks
21%synergy
Blighted Agent
21%inclusion30 decks140 decks
21%synergy
Phyrexian Swarmlord
21%inclusion30 decks140 decks
21%synergy
Gix, Yawgmoth Praetor
21%inclusion30 decks140 decks
21%synergy
Armored Scrapgorger
21%inclusion29 decks140 decks
20%synergy
Glissa Sunslayer
21%inclusion29 decks140 decks
18%synergy
Myr Convert
21%inclusion29 decks140 decks
18%synergy
Urabrask
20%inclusion28 decks140 decks
19%synergy
Venser, Corpse Puppet
19%inclusion27 decks140 decks
19%synergy
Ria Ivor, Bane of Bladehold
19%inclusion26 decks140 decks
18%synergy
Voidwing Hybrid
18%inclusion25 decks140 decks
18%synergy
Bilious Skulldweller
18%inclusion25 decks140 decks
18%synergy
Massacre Wurm
18%inclusion25 decks140 decks
17%synergy
Venomous Brutalizer
17%inclusion24 decks140 decks
17%synergy
Ichor Rats
17%inclusion24 decks140 decks
17%synergy
Mishra, Claimed by Gix
16%inclusion23 decks140 decks
16%synergy
Slaughter Singer
16%inclusion23 decks140 decks
16%synergy
Phyrexian Dragon Engine
16%inclusion22 decks140 decks
15%synergy
Soul of New Phyrexia
16%inclusion22 decks140 decks
15%synergy
Paladin of Predation
14%inclusion20 decks140 decks
14%synergy
Norn's Choirmaster
14%inclusion19 decks140 decks
13%synergy
Progenitor Exarch
14%inclusion19 decks140 decks
13%synergy
Scheming Aspirant
13%inclusion18 decks140 decks
13%synergy
Instants
Infectious Bite
34%inclusion47 decks140 decks
33%synergy
Swords to Plowshares
31%inclusion43 decks140 decks
-9%synergy
Experimental Augury
28%inclusion39 decks140 decks
27%synergy
Reject Imperfection
26%inclusion36 decks140 decks
26%synergy
Black Sun's Twilight
26%inclusion36 decks140 decks
25%synergy
Path to Exile
22%inclusion31 decks140 decks
-5%synergy
Counterspell
17%inclusion24 decks140 decks
-6%synergy
Negate
14%inclusion19 decks140 decks
5%synergy
Void Rend
12%inclusion17 decks140 decks
9%synergy
Bring the Ending
11%inclusion16 decks140 decks
11%synergy
Whisper of the Dross
11%inclusion15 decks140 decks
11%synergy
Heroic Intervention
11%inclusion15 decks140 decks
-12%synergy
Tainted Strike
10%inclusion14 decks140 decks
10%synergy
Serum Snare
10%inclusion14 decks140 decks
10%synergy
Noxious Revival
9.3%inclusion13 decks140 decks
7%synergy
Volt Charge
9.3%inclusion13 decks140 decks
9%synergy
Mana Drain
8.6%inclusion12 decks140 decks
-1%synergy
Beast Within
8.6%inclusion12 decks140 decks
-4%synergy
Charge of the Mites
8.6%inclusion12 decks140 decks
9%synergy
Atomize
8.1%inclusion10 decks123 decks
7%synergy
Dark Ritual
7.9%inclusion11 decks140 decks
2%synergy
Fuel for the Cause
7.9%inclusion11 decks140 decks
8%synergy
Radstorm
7.9%inclusion11 decks140 decks
8%synergy
Sheoldred's Edict
6.4%inclusion9 decks140 decks
6%synergy
Assassin's Trophy
5.7%inclusion8 decks140 decks
-7%synergy
Offer Immortality
5.7%inclusion8 decks140 decks
6%synergy
Corrupted Resolve
5.0%inclusion7 decks140 decks
5%synergy
Anguished Unmaking
5.0%inclusion7 decks140 decks
-3%synergy
Mortify
5.0%inclusion7 decks140 decks
2%synergy
Excise the Imperfect
5.0%inclusion7 decks140 decks
5%synergy
Brokers Confluence
5.0%inclusion7 decks140 decks
5%synergy
Sorceries
Infectious Inquiry
36%inclusion51 decks140 decks
36%synergy
Phyresis Outbreak
33%inclusion46 decks140 decks
33%synergy
Unnatural Restoration
31%inclusion44 decks140 decks
30%synergy
Farseek
28%inclusion39 decks140 decks
-16%synergy
Drown in Ichor
26%inclusion37 decks140 decks
26%synergy
Cultivate
26%inclusion36 decks140 decks
-8%synergy
Expand the Sphere
24%inclusion34 decks140 decks
24%synergy
Thirsting Roots
24%inclusion33 decks140 decks
23%synergy
Sunfall
24%inclusion33 decks140 decks
23%synergy
Green Sun's Twilight
21%inclusion29 decks140 decks
20%synergy
Tezzeret's Gambit
21%inclusion29 decks140 decks
20%synergy
Breach the Multiverse
20%inclusion28 decks140 decks
19%synergy
Triumph of the Hordes
19%inclusion27 decks140 decks
19%synergy
Blue Sun's Twilight
15%inclusion21 decks140 decks
15%synergy
Phyrexian Rebirth
15%inclusion21 decks140 decks
15%synergy
Nature's Lore
14%inclusion20 decks140 decks
-13%synergy
Kodama's Reach
14%inclusion20 decks140 decks
-8%synergy
Red Sun's Twilight
14%inclusion20 decks140 decks
14%synergy
Vat Emergence
14%inclusion19 decks140 decks
13%synergy
Rampant Growth
14%inclusion19 decks140 decks
-7%synergy
Glistening Dawn
12%inclusion17 decks140 decks
12%synergy
Three Visits
12%inclusion17 decks140 decks
-11%synergy
Noxious Assault
11%inclusion15 decks140 decks
11%synergy
Feed the Infection
10%inclusion14 decks140 decks
10%synergy
Distorted Curiosity
9.3%inclusion13 decks140 decks
9%synergy
Caress of Phyrexia
9.3%inclusion13 decks140 decks
9%synergy
Geth's Summons
7.9%inclusion11 decks140 decks
8%synergy
Kindred Dominance
7.9%inclusion11 decks140 decks
2%synergy
Vivisurgeon's Insight
7.9%inclusion11 decks140 decks
8%synergy
Praetor's Counsel
7.1%inclusion10 decks140 decks
7%synergy
Ruinous Ultimatum
7.1%inclusion10 decks140 decks
-1%synergy
Praetor's Grasp
6.4%inclusion9 decks140 decks
6%synergy
Sunder the Gateway
6.4%inclusion9 decks140 decks
6%synergy
Wurmquake
5.7%inclusion8 decks140 decks
6%synergy
Carnivorous Canopy
5.7%inclusion8 decks140 decks
6%synergy
Blasphemous Act
5.7%inclusion8 decks140 decks
-5%synergy
Eerie Ultimatum
5.0%inclusion7 decks140 decks
-3%synergy
Eyes of Gitaxias
5.0%inclusion7 decks140 decks
5%synergy
Diabolic Tutor
5.0%inclusion7 decks140 decks
1%synergy
Utility Artifacts
Portal to Phyrexia
26%inclusion37 decks140 decks
26%synergy
Monument to Perfection
21%inclusion30 decks140 decks
21%synergy
Norn's Annex
19%inclusion27 decks140 decks
19%synergy
Urabrask's Forge
16%inclusion22 decks140 decks
16%synergy
Herald's Horn
15%inclusion21 decks140 decks
-3%synergy
Contagion Engine
14%inclusion20 decks140 decks
14%synergy
Urza's Incubator
13%inclusion18 decks140 decks
-2%synergy
Lightning Greaves
13%inclusion18 decks140 decks
-4%synergy
Infested Fleshcutter
11%inclusion15 decks140 decks
11%synergy
Ichormoon Gauntlet
10%inclusion14 decks140 decks
9%synergy
Conduit of Worlds
9.3%inclusion13 decks140 decks
8%synergy
Contagion Clasp
8.6%inclusion12 decks140 decks
8%synergy
Banner of Kinship
7.5%inclusion5 decks67 decks
5%synergy
Grafted Exoskeleton
7.1%inclusion10 decks140 decks
7%synergy
Vanquisher's Banner
7.1%inclusion10 decks140 decks
0%synergy
Vat of Rebirth
6.4%inclusion9 decks140 decks
6%synergy
Bitterthorn, Nissa's Animus
6.4%inclusion9 decks140 decks
6%synergy
Jeskai Monument
6.1%inclusion2 decks33 decks
6%synergy
Abzan Monument
6.1%inclusion2 decks33 decks
6%synergy
Phyrexian Altar
5.7%inclusion8 decks140 decks
5%synergy
Doubling Cube
5.7%inclusion8 decks140 decks
5%synergy
Door of Destinies
5.0%inclusion7 decks140 decks
2%synergy
Swiftfoot Boots
5.0%inclusion7 decks140 decks
-8%synergy
Enchantments
Skrelv's Hive
44%inclusion61 decks140 decks
43%synergy
Norn's Decree
35%inclusion49 decks140 decks
35%synergy
Phyrexian Arena
32%inclusion45 decks140 decks
30%synergy
Phyrexian Awakening
31%inclusion44 decks140 decks
31%synergy
All Will Be One
29%inclusion41 decks140 decks
28%synergy
Inexorable Tide
23%inclusion32 decks140 decks
22%synergy
Tangled Skyline
20%inclusion28 decks140 decks
20%synergy
Necrogen Communion
18%inclusion25 decks140 decks
18%synergy
Leyline of the Guildpact
17%inclusion23 decks133 decks
2%synergy
Sculpted Perfection
16%inclusion22 decks140 decks
16%synergy
Phyresis
13%inclusion18 decks140 decks
13%synergy
Blighted Burgeoning
11%inclusion15 decks140 decks
11%synergy
Phyrexian Unlife
10%inclusion14 decks140 decks
10%synergy
Gift of Compleation
9.3%inclusion13 decks140 decks
9%synergy
Goliath Hatchery
8.6%inclusion12 decks140 decks
9%synergy
Glistening Oil
7.9%inclusion11 decks140 decks
8%synergy
Corrupted Conscience
7.9%inclusion11 decks140 decks
8%synergy
Corruption of Towashi
6.4%inclusion9 decks140 decks
6%synergy
Phyrexian Reclamation
6.4%inclusion9 decks140 decks
6%synergy
Kindred Discovery
6.4%inclusion9 decks140 decks
-5%synergy
Mirari's Wake
5.0%inclusion7 decks140 decks
-4%synergy
Battles
Invasion of New Capenna
5.0%inclusion7 decks140 decks
5%synergy
Invasion of Alara
5.0%inclusion7 decks140 decks
3%synergy
Planeswalkers
Nissa, Ascended Animist
22%inclusion31 decks140 decks
22%synergy
Ajani, Sleeper Agent
21%inclusion30 decks140 decks
21%synergy
Lukka, Bound to Ruin
19%inclusion26 decks140 decks
18%synergy
Tamiyo, Compleated Sage
13%inclusion18 decks140 decks
12%synergy
Jace, the Perfected Mind
11%inclusion15 decks140 decks
11%synergy
Nahiri, the Unforgiving
7.9%inclusion11 decks140 decks
8%synergy
Wrenn and Realmbreaker
7.1%inclusion10 decks140 decks
5%synergy
Utility Lands
Karn's Bastion
41%inclusion57 decks140 decks
37%synergy
Reliquary Tower
29%inclusion40 decks140 decks
2%synergy
The Dross Pits
24%inclusion33 decks140 decks
23%synergy
The Fair Basilica
24%inclusion33 decks140 decks
23%synergy
The Hunter Maze
24%inclusion33 decks140 decks
23%synergy
The Surgical Bay
22%inclusion31 decks140 decks
22%synergy
The Autonomous Furnace
22%inclusion31 decks140 decks
22%synergy
The Monumental Facade
14%inclusion20 decks140 decks
14%synergy
Rogue's Passage
11%inclusion16 decks140 decks
5%synergy
Three Tree City
11%inclusion10 decks91 decks
3%synergy
Inkmoth Nexus
10%inclusion14 decks140 decks
10%synergy
Bojuka Bog
9.3%inclusion13 decks140 decks
5%synergy
Cascading Cataracts
8.6%inclusion12 decks140 decks
-8%synergy
Boseiju, Who Endures
7.9%inclusion11 decks140 decks
-3%synergy
Urborg, Tomb of Yawgmoth
6.4%inclusion9 decks140 decks
0%synergy
Mistrise Village
6.1%inclusion2 decks33 decks
2%synergy
Phyrexian Tower
5.7%inclusion8 decks140 decks
5%synergy
Yavimaya, Cradle of Growth
5.0%inclusion7 decks140 decks
-5%synergy
Mana Artifacts
Sol Ring
76%inclusion107 decks140 decks
-3%synergy
Arcane Signet
65%inclusion91 decks140 decks
-10%synergy
Glistening Sphere
56%inclusion79 decks140 decks
56%synergy
Chromatic Lantern
51%inclusion72 decks140 decks
1%synergy
Phyrexian Atlas
45%inclusion63 decks140 decks
45%synergy
Fellwar Stone
23%inclusion32 decks140 decks
-8%synergy
Staff of Compleation
19%inclusion27 decks140 decks
19%synergy
Commander's Sphere
16%inclusion22 decks140 decks
-1%synergy
Replicating Ring
11%inclusion16 decks140 decks
10%synergy
Everflowing Chalice
11%inclusion15 decks140 decks
7%synergy
Patchwork Banner
10%inclusion9 decks89 decks
3%synergy
Chromatic Orrery
10%inclusion14 decks140 decks
0%synergy
Tablet of Compleation
7.9%inclusion11 decks140 decks
8%synergy
Astral Cornucopia
7.1%inclusion10 decks140 decks
7%synergy
Timeless Lotus
7.1%inclusion10 decks140 decks
-3%synergy
Thought Vessel
6.4%inclusion9 decks140 decks
-1%synergy
Lands
Forest
91%inclusion128 decks140 decks
11%synergy
Swamp
91%inclusion127 decks140 decks
16%synergy
Plains
91%inclusion127 decks140 decks
14%synergy
Island
90%inclusion126 decks140 decks
12%synergy
Mountain
89%inclusion124 decks140 decks
13%synergy
Command Tower
82%inclusion115 decks140 decks
-6%synergy
The Seedcore
66%inclusion92 decks140 decks
65%synergy
Path of Ancestry
49%inclusion69 decks140 decks
7%synergy
Exotic Orchard
49%inclusion68 decks140 decks
-13%synergy
Mirrex
27%inclusion38 decks140 decks
27%synergy
Breeding Pool
26%inclusion37 decks140 decks
-4%synergy
The World Tree
26%inclusion37 decks140 decks
-2%synergy
Hallowed Fountain
26%inclusion36 decks140 decks
0%synergy
Temple Garden
26%inclusion36 decks140 decks
-3%synergy
Overgrown Tomb
25%inclusion35 decks140 decks
-3%synergy
Indatha Triome
25%inclusion35 decks140 decks
3%synergy
Misty Rainforest
24%inclusion34 decks140 decks
-3%synergy
Stomping Ground
24%inclusion33 decks140 decks
-6%synergy
Watery Grave
23%inclusion32 decks140 decks
-1%synergy
Ketria Triome
22%inclusion31 decks140 decks
-2%synergy
Marsh Flats
22%inclusion31 decks140 decks
-1%synergy
Evolving Wilds
22%inclusion31 decks140 decks
2%synergy
Terramorphic Expanse
21%inclusion30 decks140 decks
6%synergy
Windswept Heath
21%inclusion30 decks140 decks
-6%synergy
The Mycosynth Gardens
21%inclusion29 decks140 decks
19%synergy
Polluted Delta
21%inclusion29 decks140 decks
-3%synergy
Sandsteppe Citadel
21%inclusion29 decks140 decks
5%synergy
Zagoth Triome
21%inclusion29 decks140 decks
-1%synergy
Opulent Palace
20%inclusion28 decks140 decks
4%synergy
Savai Triome
19%inclusion27 decks140 decks
3%synergy
Verdant Catacombs
19%inclusion27 decks140 decks
-7%synergy
Spara's Headquarters
19%inclusion26 decks140 decks
-2%synergy
Steam Vents
19%inclusion26 decks140 decks
-5%synergy
Godless Shrine
19%inclusion26 decks140 decks
-6%synergy
Arid Mesa
18%inclusion25 decks140 decks
-5%synergy
Raffine's Tower
17%inclusion24 decks140 decks
4%synergy
Scalding Tarn
17%inclusion24 decks140 decks
-6%synergy
Jetmir's Garden
17%inclusion24 decks140 decks
-3%synergy
Bloodstained Mire
17%inclusion24 decks140 decks
-5%synergy
Raugrin Triome
17%inclusion24 decks140 decks
0%synergy
Flooded Strand
17%inclusion24 decks140 decks
-8%synergy
Seaside Citadel
16%inclusion23 decks140 decks
1%synergy
Unclaimed Territory
16%inclusion23 decks140 decks
-1%synergy
Wooded Foothills
16%inclusion23 decks140 decks
-10%synergy
Arcane Sanctum
16%inclusion22 decks140 decks
4%synergy
Cavern of Souls
16%inclusion22 decks140 decks
-1%synergy
Ziatora's Proving Ground
15%inclusion21 decks140 decks
-4%synergy
Jungle Shrine
15%inclusion21 decks140 decks
-2%synergy
Sacred Foundry
14%inclusion20 decks140 decks
-9%synergy
Crumbling Necropolis
14%inclusion20 decks140 decks
3%synergy
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