Omnath, Locus of All (Commander) - Infect

Omnath, Locus of All
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Atraxa, Praetors' Voice
62%inclusion99 decks159 decks
59%synergy
Ixhel, Scion of Atraxa
59%inclusion94 decks159 decks
59%synergy
Urabrask the Hidden
58%inclusion93 decks159 decks
57%synergy
Prologue to Phyresis
55%inclusion88 decks159 decks
55%synergy
Elesh Norn
56%inclusion89 decks159 decks
55%synergy
Realmbreaker, the Invasion Tree
54%inclusion86 decks159 decks
53%synergy
Vraska, Betrayal's Sting
52%inclusion82 decks159 decks
50%synergy
Vishgraz, the Doomhive
50%inclusion79 decks159 decks
50%synergy
Venerated Rotpriest
50%inclusion79 decks159 decks
50%synergy
Brimaz, Blight of Oreskos
49%inclusion78 decks159 decks
49%synergy
Top Cards
Skrelv, Defector Mite
49%inclusion78 decks159 decks
47%synergy
Vraska's Fall
48%inclusion77 decks159 decks
48%synergy
Tekuthal, Inquiry Dominus
48%inclusion77 decks159 decks
48%synergy
Vorinclex, Monstrous Raider
48%inclusion77 decks159 decks
46%synergy
Thrummingbird
48%inclusion77 decks159 decks
48%synergy
Bloated Contaminator
48%inclusion76 decks159 decks
48%synergy
Jin-Gitaxias
48%inclusion76 decks159 decks
46%synergy
White Sun's Twilight
47%inclusion75 decks159 decks
47%synergy
Phyrexian Censor
47%inclusion74 decks159 decks
46%synergy
Elesh Norn, Grand Cenobite
46%inclusion73 decks159 decks
44%synergy
Game Changers
Smothering Tithe
14%inclusion22 decks159 decks
-5%synergy
Rhystic Study
13%inclusion21 decks159 decks
-8%synergy
Cyclonic Rift
12%inclusion19 decks159 decks
-5%synergy
Demonic Tutor
11%inclusion17 decks159 decks
-8%synergy
Vampiric Tutor
11%inclusion17 decks159 decks
-4%synergy
Enlightened Tutor
8.8%inclusion14 decks159 decks
-5%synergy
Mystical Tutor
6.3%inclusion10 decks159 decks
0%synergy
Teferi's Protection
6.3%inclusion10 decks159 decks
-9%synergy
Creatures
Sheoldred
46%inclusion73 decks159 decks
44%synergy
Cankerbloom
46%inclusion73 decks159 decks
45%synergy
Sheoldred, Whispering One
45%inclusion71 decks159 decks
43%synergy
Atraxa, Grand Unifier
45%inclusion71 decks159 decks
41%synergy
Ezuri, Stalker of Spheres
42%inclusion67 decks159 decks
42%synergy
Vorinclex, Voice of Hunger
42%inclusion67 decks159 decks
40%synergy
Glissa, Herald of Predation
42%inclusion66 decks159 decks
41%synergy
Elesh Norn, Mother of Machines
40%inclusion64 decks159 decks
38%synergy
Jin-Gitaxias, Core Augur
38%inclusion61 decks159 decks
37%synergy
Vorinclex
36%inclusion58 decks159 decks
35%synergy
Jin-Gitaxias, Progress Tyrant
36%inclusion58 decks159 decks
35%synergy
Contaminant Grafter
36%inclusion57 decks159 decks
36%synergy
Phyrexian Obliterator
35%inclusion56 decks159 decks
35%synergy
Tainted Observer
34%inclusion54 decks159 decks
34%synergy
Tyrranax Rex
34%inclusion54 decks159 decks
34%synergy
Sheoldred, the Apocalypse
33%inclusion53 decks159 decks
32%synergy
Grafted Butcher
31%inclusion49 decks159 decks
31%synergy
Zopandrel, Hunger Dominus
30%inclusion47 decks159 decks
29%synergy
Skithiryx, the Blight Dragon
29%inclusion46 decks159 decks
28%synergy
Phyrexian Vindicator
29%inclusion46 decks159 decks
29%synergy
Blightbelly Rat
29%inclusion46 decks159 decks
29%synergy
Etali, Primal Conqueror
28%inclusion45 decks159 decks
26%synergy
Necrogen Rotpriest
28%inclusion45 decks159 decks
28%synergy
Metastatic Evangel
27%inclusion28 decks104 decks
27%synergy
Essence of Orthodoxy
24%inclusion38 decks159 decks
24%synergy
Myr Convert
23%inclusion36 decks159 decks
20%synergy
Gix, Yawgmoth Praetor
23%inclusion36 decks159 decks
22%synergy
Blighted Agent
23%inclusion36 decks159 decks
23%synergy
Mondrak, Glory Dominus
23%inclusion36 decks159 decks
21%synergy
Urabrask, Heretic Praetor
22%inclusion35 decks159 decks
21%synergy
Phyrexian Swarmlord
22%inclusion35 decks159 decks
22%synergy
Armored Scrapgorger
21%inclusion34 decks159 decks
21%synergy
Blightsteel Colossus
21%inclusion33 decks159 decks
20%synergy
Urabrask
21%inclusion33 decks159 decks
20%synergy
Glissa Sunslayer
19%inclusion31 decks159 decks
17%synergy
Slaughter Singer
18%inclusion29 decks159 decks
18%synergy
Bilious Skulldweller
18%inclusion29 decks159 decks
18%synergy
Venser, Corpse Puppet
18%inclusion28 decks159 decks
18%synergy
Voidwing Hybrid
17%inclusion27 decks159 decks
17%synergy
Venomous Brutalizer
17%inclusion27 decks159 decks
17%synergy
Massacre Wurm
17%inclusion27 decks159 decks
17%synergy
Ichor Rats
17%inclusion27 decks159 decks
17%synergy
Ria Ivor, Bane of Bladehold
16%inclusion26 decks159 decks
16%synergy
Mishra, Claimed by Gix
16%inclusion25 decks159 decks
15%synergy
Phyrexian Dragon Engine
15%inclusion24 decks159 decks
15%synergy
Norn's Choirmaster
14%inclusion23 decks159 decks
14%synergy
Paladin of Predation
14%inclusion22 decks159 decks
14%synergy
Soul of New Phyrexia
14%inclusion22 decks159 decks
14%synergy
Progenitor Exarch
13%inclusion20 decks159 decks
12%synergy
Scheming Aspirant
13%inclusion20 decks159 decks
13%synergy
Instants
Infectious Bite
35%inclusion55 decks159 decks
35%synergy
Swords to Plowshares
28%inclusion45 decks159 decks
-11%synergy
Experimental Augury
27%inclusion43 decks159 decks
26%synergy
Black Sun's Twilight
25%inclusion40 decks159 decks
25%synergy
Reject Imperfection
23%inclusion36 decks159 decks
22%synergy
Path to Exile
21%inclusion33 decks159 decks
-7%synergy
Counterspell
14%inclusion23 decks159 decks
-8%synergy
Negate
13%inclusion21 decks159 decks
4%synergy
Whisper of the Dross
13%inclusion20 decks159 decks
12%synergy
Void Rend
12%inclusion19 decks159 decks
8%synergy
Tainted Strike
11%inclusion17 decks159 decks
11%synergy
Heroic Intervention
11%inclusion17 decks159 decks
-12%synergy
Beast Within
11%inclusion17 decks159 decks
-2%synergy
Serum Snare
11%inclusion17 decks159 decks
10%synergy
Noxious Revival
10%inclusion16 decks159 decks
8%synergy
Bring the Ending
8.8%inclusion14 decks159 decks
9%synergy
Fuel for the Cause
8.2%inclusion13 decks159 decks
8%synergy
Atomize
7.7%inclusion10 decks130 decks
7%synergy
Volt Charge
7.5%inclusion12 decks159 decks
7%synergy
Sheoldred's Edict
7.5%inclusion12 decks159 decks
7%synergy
Mana Drain
7.5%inclusion12 decks159 decks
-2%synergy
Charge of the Mites
7.5%inclusion12 decks159 decks
8%synergy
Offer Immortality
6.9%inclusion11 decks159 decks
7%synergy
Radstorm
6.9%inclusion11 decks159 decks
7%synergy
Dark Ritual
6.3%inclusion10 decks159 decks
1%synergy
Corrupted Resolve
6.3%inclusion10 decks159 decks
6%synergy
Assassin's Trophy
5.7%inclusion9 decks159 decks
-8%synergy
Excise the Imperfect
5.0%inclusion8 decks159 decks
5%synergy
Brokers Confluence
5.0%inclusion8 decks159 decks
5%synergy
Anoint with Affliction
5.0%inclusion8 decks159 decks
5%synergy
Mortify
5.0%inclusion8 decks159 decks
2%synergy
Sorceries
Infectious Inquiry
39%inclusion62 decks159 decks
39%synergy
Phyresis Outbreak
35%inclusion56 decks159 decks
35%synergy
Unnatural Restoration
33%inclusion52 decks159 decks
32%synergy
Farseek
28%inclusion45 decks159 decks
-15%synergy
Drown in Ichor
28%inclusion44 decks159 decks
27%synergy
Expand the Sphere
26%inclusion41 decks159 decks
25%synergy
Cultivate
25%inclusion40 decks159 decks
-9%synergy
Sunfall
23%inclusion37 decks159 decks
23%synergy
Thirsting Roots
23%inclusion36 decks159 decks
22%synergy
Breach the Multiverse
21%inclusion34 decks159 decks
20%synergy
Tezzeret's Gambit
21%inclusion33 decks159 decks
20%synergy
Green Sun's Twilight
21%inclusion33 decks159 decks
20%synergy
Triumph of the Hordes
19%inclusion31 decks159 decks
19%synergy
Blue Sun's Twilight
16%inclusion25 decks159 decks
15%synergy
Red Sun's Twilight
15%inclusion24 decks159 decks
15%synergy
Kodama's Reach
15%inclusion24 decks159 decks
-7%synergy
Vat Emergence
14%inclusion23 decks159 decks
14%synergy
Phyrexian Rebirth
14%inclusion23 decks159 decks
14%synergy
Nature's Lore
14%inclusion23 decks159 decks
-12%synergy
Rampant Growth
13%inclusion20 decks159 decks
-8%synergy
Three Visits
11%inclusion18 decks159 decks
-12%synergy
Noxious Assault
11%inclusion17 decks159 decks
11%synergy
Glistening Dawn
11%inclusion17 decks159 decks
11%synergy
Feed the Infection
9.4%inclusion15 decks159 decks
9%synergy
Distorted Curiosity
9.4%inclusion15 decks159 decks
9%synergy
Caress of Phyrexia
9.4%inclusion15 decks159 decks
9%synergy
Vivisurgeon's Insight
7.5%inclusion12 decks159 decks
7%synergy
Geth's Summons
7.5%inclusion12 decks159 decks
8%synergy
Kindred Dominance
7.5%inclusion12 decks159 decks
2%synergy
Praetor's Grasp
6.9%inclusion11 decks159 decks
6%synergy
Ruinous Ultimatum
6.9%inclusion11 decks159 decks
-1%synergy
Eerie Ultimatum
6.3%inclusion10 decks159 decks
-1%synergy
Praetor's Counsel
6.3%inclusion10 decks159 decks
6%synergy
Sunder the Gateway
5.7%inclusion9 decks159 decks
6%synergy
Wurmquake
5.7%inclusion9 decks159 decks
6%synergy
Carnivorous Canopy
5.7%inclusion9 decks159 decks
6%synergy
Contentious Plan
5.7%inclusion9 decks159 decks
5%synergy
Eyes of Gitaxias
5.0%inclusion8 decks159 decks
5%synergy
Night's Whisper
5.0%inclusion8 decks159 decks
4%synergy
Utility Artifacts
Monument to Perfection
27%inclusion43 decks159 decks
27%synergy
Portal to Phyrexia
26%inclusion41 decks159 decks
25%synergy
Norn's Annex
18%inclusion29 decks159 decks
17%synergy
Contagion Engine
16%inclusion26 decks159 decks
16%synergy
Urabrask's Forge
16%inclusion25 decks159 decks
16%synergy
Herald's Horn
15%inclusion24 decks159 decks
-3%synergy
Urza's Incubator
14%inclusion22 decks159 decks
-1%synergy
Lightning Greaves
14%inclusion22 decks159 decks
-4%synergy
Ichormoon Gauntlet
12%inclusion19 decks159 decks
10%synergy
Contagion Clasp
10%inclusion16 decks159 decks
10%synergy
Infested Fleshcutter
10%inclusion16 decks159 decks
10%synergy
Conduit of Worlds
9.4%inclusion15 decks159 decks
8%synergy
Banner of Kinship
8.8%inclusion6 decks68 decks
6%synergy
Swiftfoot Boots
6.9%inclusion11 decks159 decks
-6%synergy
Grafted Exoskeleton
6.9%inclusion11 decks159 decks
7%synergy
Vanquisher's Banner
6.3%inclusion10 decks159 decks
-1%synergy
Bitterthorn, Nissa's Animus
6.3%inclusion10 decks159 decks
6%synergy
Vat of Rebirth
5.7%inclusion9 decks159 decks
6%synergy
Phyrexian Altar
5.7%inclusion9 decks159 decks
5%synergy
Doubling Cube
5.7%inclusion9 decks159 decks
5%synergy
Enchantments
Skrelv's Hive
45%inclusion72 decks159 decks
45%synergy
Norn's Decree
36%inclusion58 decks159 decks
36%synergy
Phyrexian Arena
32%inclusion51 decks159 decks
30%synergy
Phyrexian Awakening
31%inclusion50 decks159 decks
31%synergy
All Will Be One
28%inclusion45 decks159 decks
27%synergy
Inexorable Tide
23%inclusion37 decks159 decks
22%synergy
Tangled Skyline
19%inclusion31 decks159 decks
19%synergy
Leyline of the Guildpact
18%inclusion25 decks141 decks
2%synergy
Necrogen Communion
16%inclusion26 decks159 decks
16%synergy
Sculpted Perfection
16%inclusion25 decks159 decks
16%synergy
Phyresis
12%inclusion19 decks159 decks
12%synergy
Phyrexian Unlife
11%inclusion18 decks159 decks
11%synergy
Gift of Compleation
10%inclusion16 decks159 decks
10%synergy
Goliath Hatchery
9.4%inclusion15 decks159 decks
9%synergy
Blighted Burgeoning
9.4%inclusion15 decks159 decks
9%synergy
Glistening Oil
8.8%inclusion14 decks159 decks
9%synergy
Corrupted Conscience
8.2%inclusion13 decks159 decks
8%synergy
Corruption of Towashi
6.3%inclusion10 decks159 decks
6%synergy
Phyrexian Reclamation
6.3%inclusion10 decks159 decks
6%synergy
Kindred Discovery
6.3%inclusion10 decks159 decks
-5%synergy
Mirari's Wake
5.0%inclusion8 decks159 decks
-4%synergy
Battles
Invasion of Alara
5.7%inclusion9 decks159 decks
4%synergy
Planeswalkers
Ajani, Sleeper Agent
22%inclusion35 decks159 decks
21%synergy
Nissa, Ascended Animist
21%inclusion33 decks159 decks
20%synergy
Lukka, Bound to Ruin
19%inclusion30 decks159 decks
19%synergy
Tamiyo, Compleated Sage
13%inclusion20 decks159 decks
12%synergy
Jace, the Perfected Mind
10%inclusion16 decks159 decks
10%synergy
Nahiri, the Unforgiving
6.9%inclusion11 decks159 decks
7%synergy
Wrenn and Realmbreaker
5.7%inclusion9 decks159 decks
3%synergy
Utility Lands
Karn's Bastion
40%inclusion63 decks159 decks
36%synergy
The Dross Pits
25%inclusion40 decks159 decks
25%synergy
The Hunter Maze
25%inclusion40 decks159 decks
25%synergy
Reliquary Tower
25%inclusion40 decks159 decks
-1%synergy
The Fair Basilica
25%inclusion39 decks159 decks
24%synergy
The Surgical Bay
23%inclusion37 decks159 decks
23%synergy
The Autonomous Furnace
23%inclusion36 decks159 decks
23%synergy
The Monumental Facade
15%inclusion24 decks159 decks
15%synergy
Inkmoth Nexus
12%inclusion19 decks159 decks
12%synergy
Three Tree City
12%inclusion11 decks94 decks
4%synergy
Rogue's Passage
11%inclusion17 decks159 decks
4%synergy
Bojuka Bog
9.4%inclusion15 decks159 decks
5%synergy
Mistrise Village
9.4%inclusion3 decks32 decks
5%synergy
Cascading Cataracts
8.8%inclusion14 decks159 decks
-7%synergy
Boseiju, Who Endures
8.2%inclusion13 decks159 decks
-3%synergy
Yavimaya, Cradle of Growth
5.7%inclusion9 decks159 decks
-5%synergy
Urborg, Tomb of Yawgmoth
5.7%inclusion9 decks159 decks
-1%synergy
Phyrexian Tower
5.0%inclusion8 decks159 decks
4%synergy
Mana Artifacts
Sol Ring
77%inclusion122 decks159 decks
-2%synergy
Arcane Signet
66%inclusion105 decks159 decks
-9%synergy
Glistening Sphere
60%inclusion96 decks159 decks
60%synergy
Chromatic Lantern
50%inclusion80 decks159 decks
0%synergy
Phyrexian Atlas
47%inclusion75 decks159 decks
47%synergy
Fellwar Stone
22%inclusion35 decks159 decks
-9%synergy
Staff of Compleation
20%inclusion32 decks159 decks
19%synergy
Commander's Sphere
17%inclusion27 decks159 decks
0%synergy
Chromatic Orrery
13%inclusion20 decks159 decks
2%synergy
Patchwork Banner
11%inclusion10 decks92 decks
4%synergy
Replicating Ring
11%inclusion17 decks159 decks
9%synergy
Everflowing Chalice
11%inclusion17 decks159 decks
7%synergy
Tablet of Compleation
8.2%inclusion13 decks159 decks
8%synergy
Astral Cornucopia
7.5%inclusion12 decks159 decks
7%synergy
Thought Vessel
6.3%inclusion10 decks159 decks
-1%synergy
Timeless Lotus
6.3%inclusion10 decks159 decks
-4%synergy
Lands
Swamp
92%inclusion146 decks159 decks
17%synergy
Forest
92%inclusion146 decks159 decks
12%synergy
Plains
91%inclusion144 decks159 decks
14%synergy
Island
90%inclusion143 decks159 decks
12%synergy
Mountain
89%inclusion141 decks159 decks
13%synergy
Command Tower
81%inclusion129 decks159 decks
-7%synergy
The Seedcore
66%inclusion105 decks159 decks
66%synergy
Path of Ancestry
50%inclusion79 decks159 decks
7%synergy
Exotic Orchard
49%inclusion78 decks159 decks
-13%synergy
Mirrex
29%inclusion46 decks159 decks
29%synergy
Breeding Pool
27%inclusion43 decks159 decks
-3%synergy
Hallowed Fountain
26%inclusion42 decks159 decks
1%synergy
The World Tree
26%inclusion42 decks159 decks
-3%synergy
Overgrown Tomb
26%inclusion41 decks159 decks
-2%synergy
Temple Garden
26%inclusion41 decks159 decks
-3%synergy
Misty Rainforest
24%inclusion38 decks159 decks
-3%synergy
Stomping Ground
24%inclusion38 decks159 decks
-5%synergy
Indatha Triome
24%inclusion38 decks159 decks
1%synergy
Watery Grave
23%inclusion36 decks159 decks
-1%synergy
The Mycosynth Gardens
22%inclusion35 decks159 decks
21%synergy
Marsh Flats
21%inclusion34 decks159 decks
-2%synergy
Ketria Triome
21%inclusion33 decks159 decks
-4%synergy
Windswept Heath
20%inclusion32 decks159 decks
-7%synergy
Verdant Catacombs
19%inclusion30 decks159 decks
-7%synergy
Godless Shrine
19%inclusion30 decks159 decks
-6%synergy
Polluted Delta
19%inclusion30 decks159 decks
-5%synergy
Terramorphic Expanse
19%inclusion30 decks159 decks
4%synergy
Evolving Wilds
19%inclusion30 decks159 decks
-1%synergy
Steam Vents
18%inclusion29 decks159 decks
-5%synergy
Opulent Palace
18%inclusion29 decks159 decks
2%synergy
Zagoth Triome
18%inclusion29 decks159 decks
-3%synergy
Sandsteppe Citadel
18%inclusion28 decks159 decks
2%synergy
Savai Triome
17%inclusion27 decks159 decks
1%synergy
Jetmir's Garden
17%inclusion27 decks159 decks
-3%synergy
Spara's Headquarters
17%inclusion27 decks159 decks
-4%synergy
Unclaimed Territory
16%inclusion26 decks159 decks
-1%synergy
Arid Mesa
16%inclusion26 decks159 decks
-7%synergy
Bloodstained Mire
16%inclusion26 decks159 decks
-6%synergy
Scalding Tarn
16%inclusion25 decks159 decks
-7%synergy
Seaside Citadel
16%inclusion25 decks159 decks
1%synergy
Raffine's Tower
16%inclusion25 decks159 decks
2%synergy
Arcane Sanctum
16%inclusion25 decks159 decks
4%synergy
Cavern of Souls
16%inclusion25 decks159 decks
-1%synergy
Raugrin Triome
16%inclusion25 decks159 decks
-2%synergy
Flooded Strand
16%inclusion25 decks159 decks
-9%synergy
Wooded Foothills
15%inclusion24 decks159 decks
-11%synergy
Crumbling Necropolis
15%inclusion24 decks159 decks
4%synergy
Sacred Foundry
15%inclusion24 decks159 decks
-8%synergy
Ziatora's Proving Ground
14%inclusion23 decks159 decks
-4%synergy
Blood Crypt
14%inclusion23 decks159 decks
-6%synergy
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