Sheoldred, the Apocalypse (Commander) - Infect

Sheoldred, the Apocalypse
Rank #177
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Zoe Ley
Apr 14, 2026
Zoe Ley
The 10 Best Prepared Cards in Secrets of Strixhaven
The new prepared mechanic from Secrets of Strixhaven looks like it'll have some very strong cards for Commander. But which ones are the best?
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Bilious Skulldweller
63%inclusion17 decks27 decks
62%synergy
Skithiryx, the Blight Dragon
59%inclusion16 decks27 decks
58%synergy
Vraska, Betrayal's Sting
59%inclusion16 decks27 decks
57%synergy
Blightbelly Rat
59%inclusion16 decks27 decks
56%synergy
Vraska's Fall
56%inclusion15 decks27 decks
52%synergy
Plague Stinger
48%inclusion13 decks27 decks
47%synergy
Phyrexian Obliterator
56%inclusion15 decks27 decks
44%synergy
Caress of Phyrexia
44%inclusion12 decks27 decks
44%synergy
Infectious Inquiry
44%inclusion12 decks27 decks
42%synergy
Phyrexian Crusader
41%inclusion11 decks27 decks
40%synergy
Top Cards
Dark Ritual
70%inclusion19 decks27 decks
4%synergy
Phyrexian Arena
63%inclusion17 decks27 decks
23%synergy
Jet Medallion
59%inclusion16 decks27 decks
-3%synergy
Sign in Blood
59%inclusion16 decks27 decks
24%synergy
K'rrik, Son of Yawgmoth
52%inclusion14 decks27 decks
33%synergy
Peer into the Abyss
44%inclusion12 decks27 decks
34%synergy
Sheoldred, Whispering One
44%inclusion12 decks27 decks
33%synergy
Sheoldred's Edict
41%inclusion11 decks27 decks
26%synergy
Underworld Dreams
41%inclusion11 decks27 decks
35%synergy
Gixian Puppeteer
41%inclusion11 decks27 decks
37%synergy
Game Changers
Demonic Tutor
41%inclusion11 decks27 decks
13%synergy
Vampiric Tutor
33%inclusion9 decks27 decks
12%synergy
The One Ring
26%inclusion7 decks27 decks
17%synergy
Orcish Bowmasters
26%inclusion7 decks27 decks
13%synergy
Ancient Tomb
22%inclusion6 decks27 decks
11%synergy
Bolas's Citadel
19%inclusion5 decks27 decks
-10%synergy
Mana Vault
15%inclusion4 decks27 decks
8%synergy
Imperial Seal
11%inclusion3 decks27 decks
4%synergy
Chrome Mox
11%inclusion3 decks27 decks
5%synergy
Creatures
Scrawling Crawler
38%inclusion5 decks13 decks
35%synergy
Pestilent Syphoner
37%inclusion10 decks27 decks
36%synergy
Reaper of Sheoldred
37%inclusion10 decks27 decks
36%synergy
Psychosis Crawler
37%inclusion10 decks27 decks
33%synergy
Plague Myr
37%inclusion10 decks27 decks
36%synergy
Drivnod, Carnage Dominus
37%inclusion10 decks27 decks
30%synergy
Massacre Wurm
37%inclusion10 decks27 decks
20%synergy
Sheoldred's Headcleaver
37%inclusion10 decks27 decks
37%synergy
Vraan, Executioner Thane
37%inclusion10 decks27 decks
34%synergy
Hand of the Praetors
37%inclusion10 decks27 decks
36%synergy
Whispering Specter
33%inclusion9 decks27 decks
33%synergy
Defiler of Flesh
33%inclusion9 decks27 decks
29%synergy
Vito, Thorn of the Dusk Rose
33%inclusion9 decks27 decks
23%synergy
Ichorclaw Myr
33%inclusion9 decks27 decks
33%synergy
Sheoldred
33%inclusion9 decks27 decks
27%synergy
Ichor Rats
33%inclusion9 decks27 decks
30%synergy
Seizan, Perverter of Truth
30%inclusion8 decks27 decks
26%synergy
Bloodletter of Aclazotz
30%inclusion8 decks27 decks
19%synergy
Grafted Butcher
30%inclusion8 decks27 decks
29%synergy
Crypt Ghast
30%inclusion8 decks27 decks
-18%synergy
Unstoppable Slasher
26%inclusion5 decks19 decks
21%synergy
Core Prowler
26%inclusion7 decks27 decks
25%synergy
Zenith Chronicler
26%inclusion7 decks27 decks
25%synergy
Scheming Aspirant
26%inclusion7 decks27 decks
26%synergy
Gulping Scraptrap
26%inclusion7 decks27 decks
25%synergy
Bloodthirsty Conqueror
23%inclusion3 decks13 decks
14%synergy
Yawgmoth, Thran Physician
22%inclusion6 decks27 decks
12%synergy
Nimraiser Paladin
22%inclusion6 decks27 decks
22%synergy
Phyrexian Rager
22%inclusion6 decks27 decks
22%synergy
Dauthi Voidwalker
22%inclusion6 decks27 decks
7%synergy
Contagious Nim
19%inclusion5 decks27 decks
18%synergy
Dread Presence
19%inclusion5 decks27 decks
5%synergy
Magus of the Coffers
19%inclusion5 decks27 decks
12%synergy
Flensermite
19%inclusion5 decks27 decks
18%synergy
Cruel Grimnarch
19%inclusion5 decks27 decks
18%synergy
Marauding Blight-Priest
19%inclusion5 decks27 decks
12%synergy
Kinzu of the Bleak Coven
19%inclusion5 decks27 decks
18%synergy
Blightsteel Colossus
19%inclusion5 decks27 decks
18%synergy
Evolved Sleeper
15%inclusion4 decks27 decks
14%synergy
Gray Merchant of Asphodel
15%inclusion4 decks27 decks
-36%synergy
Myr Convert
15%inclusion4 decks27 decks
14%synergy
Stinging Hivemaster
15%inclusion4 decks27 decks
15%synergy
Kozilek, Butcher of Truth
15%inclusion4 decks27 decks
14%synergy
Corpse Cur
15%inclusion4 decks27 decks
14%synergy
Phyrexian Gargantua
15%inclusion4 decks27 decks
15%synergy
Septic Rats
15%inclusion4 decks27 decks
13%synergy
Testament Bearer
15%inclusion4 decks27 decks
15%synergy
Phyrexian Fleshgorger
15%inclusion4 decks27 decks
14%synergy
Enduring Tenacity
12%inclusion3 decks25 decks
4%synergy
Master of the Feast
11%inclusion3 decks27 decks
9%synergy
Instants
Black Sun's Twilight
33%inclusion9 decks27 decks
30%synergy
Archenemy's Charm
33%inclusion1 decks3 decks
25%synergy
Withering Torment
26%inclusion5 decks19 decks
-5%synergy
Whisper of the Dross
26%inclusion7 decks27 decks
23%synergy
Blood Pact
26%inclusion7 decks27 decks
22%synergy
Go for the Throat
22%inclusion6 decks27 decks
-1%synergy
Murder
22%inclusion6 decks27 decks
12%synergy
Tainted Strike
22%inclusion6 decks27 decks
19%synergy
Dismember
22%inclusion6 decks27 decks
12%synergy
Deadly Rollick
19%inclusion5 decks27 decks
-6%synergy
Grim Affliction
19%inclusion5 decks27 decks
17%synergy
Baleful Mastery
19%inclusion5 decks27 decks
10%synergy
Anoint with Affliction
15%inclusion4 decks27 decks
14%synergy
Defile
15%inclusion4 decks27 decks
-21%synergy
Virulent Wound
15%inclusion4 decks27 decks
14%synergy
Darkness
15%inclusion4 decks27 decks
5%synergy
Offer Immortality
15%inclusion4 decks27 decks
13%synergy
Fell the Profane
11%inclusion3 decks27 decks
-8%synergy
Geth's Verdict
11%inclusion3 decks27 decks
11%synergy
Cut Down
11%inclusion3 decks27 decks
7%synergy
Village Rites
11%inclusion3 decks27 decks
-14%synergy
Doom Blade
11%inclusion3 decks27 decks
4%synergy
Infernal Grasp
11%inclusion3 decks27 decks
-14%synergy
Malakir Rebirth
11%inclusion3 decks27 decks
-12%synergy
Feign Death
11%inclusion3 decks27 decks
3%synergy
Entomb
7.4%inclusion2 decks27 decks
-5%synergy
Imp's Mischief
7.4%inclusion2 decks27 decks
-17%synergy
Songs of the Damned
7.4%inclusion2 decks27 decks
2%synergy
Cabal Ritual
7.4%inclusion2 decks27 decks
-11%synergy
Supernatural Stamina
7.4%inclusion2 decks27 decks
0%synergy
Corrupted Conviction
7.4%inclusion2 decks27 decks
-5%synergy
Sorceries
Toxic Deluge
41%inclusion11 decks27 decks
4%synergy
Insatiable Avarice
37%inclusion10 decks27 decks
25%synergy
Feed the Infection
33%inclusion9 decks27 decks
33%synergy
Black Sun's Zenith
30%inclusion8 decks27 decks
24%synergy
Vat Emergence
30%inclusion8 decks27 decks
28%synergy
Damnable Pact
30%inclusion8 decks27 decks
26%synergy
Drown in Ichor
30%inclusion8 decks27 decks
26%synergy
Phyresis Outbreak
26%inclusion7 decks27 decks
24%synergy
Feed the Swarm
26%inclusion7 decks27 decks
-25%synergy
Night's Whisper
26%inclusion7 decks27 decks
1%synergy
Dark Deal
26%inclusion7 decks27 decks
15%synergy
Damnation
26%inclusion7 decks27 decks
5%synergy
Monumental Corruption
22%inclusion6 decks27 decks
21%synergy
Rush of Dread
19%inclusion5 decks27 decks
15%synergy
Torment of Hailfire
19%inclusion5 decks27 decks
3%synergy
Annihilating Glare
19%inclusion5 decks27 decks
17%synergy
Geth's Summons
19%inclusion5 decks27 decks
18%synergy
Beseech the Mirror
19%inclusion5 decks27 decks
12%synergy
Mutilate
15%inclusion4 decks27 decks
-2%synergy
Mind Twist
15%inclusion4 decks27 decks
14%synergy
Exsanguinate
15%inclusion4 decks27 decks
-10%synergy
Reanimate
15%inclusion4 decks27 decks
-25%synergy
Grim Tutor
15%inclusion4 decks27 decks
3%synergy
Life's Finale
11%inclusion3 decks27 decks
10%synergy
Diabolic Tutor
11%inclusion3 decks27 decks
-3%synergy
Bubbling Muck
11%inclusion3 decks27 decks
-4%synergy
Read the Bones
11%inclusion3 decks27 decks
-6%synergy
In Garruk's Wake
11%inclusion3 decks27 decks
7%synergy
Invoke Despair
11%inclusion3 decks27 decks
9%synergy
Cruelclaw's Heist
8.3%inclusion2 decks24 decks
6%synergy
Spread the Sickness
7.4%inclusion2 decks27 decks
7%synergy
Eldritch Pact
7.4%inclusion2 decks27 decks
6%synergy
Disentomb
7.4%inclusion2 decks27 decks
6%synergy
Rise of the Dark Realms
7.4%inclusion2 decks27 decks
-6%synergy
Demonic Counsel
5.3%inclusion1 decks19 decks
2%synergy
Utility Artifacts
Swiftfoot Boots
33%inclusion9 decks27 decks
2%synergy
Howling Mine
33%inclusion9 decks27 decks
29%synergy
Teferi's Puzzle Box
26%inclusion7 decks27 decks
23%synergy
Lightning Greaves
26%inclusion7 decks27 decks
-8%synergy
Temple Bell
26%inclusion7 decks27 decks
24%synergy
The Darkness Crystal
25%inclusion1 decks4 decks
5%synergy
Mithril Coat
22%inclusion6 decks27 decks
17%synergy
Grafted Exoskeleton
22%inclusion6 decks27 decks
21%synergy
Vat of Rebirth
19%inclusion5 decks27 decks
15%synergy
Contagion Engine
19%inclusion5 decks27 decks
17%synergy
Aetherflux Reservoir
19%inclusion5 decks27 decks
9%synergy
Font of Mythos
19%inclusion5 decks27 decks
16%synergy
Commander's Plate
19%inclusion5 decks27 decks
13%synergy
Portal to Phyrexia
15%inclusion4 decks27 decks
13%synergy
Contagion Clasp
15%inclusion4 decks27 decks
13%synergy
Mindcrank
15%inclusion4 decks27 decks
9%synergy
Alhammarret's Archive
15%inclusion4 decks27 decks
11%synergy
Amulet of Vigor
15%inclusion4 decks27 decks
14%synergy
Dross Skullbomb
11%inclusion3 decks27 decks
11%synergy
Helm of Obedience
11%inclusion3 decks27 decks
11%synergy
Prosthetic Injector
11%inclusion3 decks27 decks
11%synergy
Shadowspear
11%inclusion3 decks27 decks
7%synergy
Sensei's Divining Top
7.4%inclusion2 decks27 decks
-1%synergy
Wayfarer's Bauble
7.4%inclusion2 decks27 decks
-8%synergy
Shrine of Limitless Power
7.4%inclusion2 decks27 decks
7%synergy
Bontu's Monument
7.4%inclusion2 decks27 decks
-21%synergy
Darksteel Plate
7.4%inclusion2 decks27 decks
5%synergy
Endless Atlas
7.4%inclusion2 decks27 decks
5%synergy
Black Vise
7.4%inclusion2 decks27 decks
7%synergy
Monument to Perfection
7.4%inclusion2 decks27 decks
7%synergy
Enchantments
Necrogen Communion
41%inclusion11 decks27 decks
39%synergy
Sanguine Bond
33%inclusion9 decks27 decks
21%synergy
Black Market Connections
33%inclusion9 decks27 decks
9%synergy
Glistening Oil
30%inclusion8 decks27 decks
29%synergy
Exquisite Blood
30%inclusion8 decks27 decks
16%synergy
Phyresis
26%inclusion7 decks27 decks
24%synergy
The Meathook Massacre
22%inclusion6 decks27 decks
5%synergy
Call of the Ring
19%inclusion5 decks27 decks
16%synergy
No Mercy
19%inclusion5 decks27 decks
11%synergy
Grievous Wound
16%inclusion3 decks19 decks
14%synergy
Greed
11%inclusion3 decks27 decks
4%synergy
Blowfly Infestation
11%inclusion3 decks27 decks
9%synergy
Phyrexian Reclamation
11%inclusion3 decks27 decks
1%synergy
Enslave
11%inclusion3 decks27 decks
11%synergy
Necrodominance
11%inclusion3 decks27 decks
8%synergy
Wound Reflection
11%inclusion3 decks27 decks
8%synergy
Dauthi Embrace
11%inclusion3 decks27 decks
9%synergy
Painful Quandary
11%inclusion3 decks27 decks
1%synergy
Revel in Riches
11%inclusion3 decks27 decks
6%synergy
Bloodchief Ascension
11%inclusion3 decks27 decks
2%synergy
Leyline of the Void
11%inclusion3 decks27 decks
9%synergy
Waste Not
7.4%inclusion2 decks27 decks
-3%synergy
Polluted Bonds
7.4%inclusion2 decks27 decks
5%synergy
Black Market
7.4%inclusion2 decks27 decks
-14%synergy
The Cruelty of Gix
7.4%inclusion2 decks27 decks
6%synergy
Crumbling Ashes
7.4%inclusion2 decks27 decks
6%synergy
Evil Presence
7.4%inclusion2 decks27 decks
7%synergy
Grave Pact
7.4%inclusion2 decks27 decks
-12%synergy
Dictate of Erebos
7.4%inclusion2 decks27 decks
-4%synergy
Liliana's Caress
7.4%inclusion2 decks27 decks
2%synergy
Kaya's Ghostform
7.4%inclusion2 decks27 decks
-3%synergy
Gate to Phyrexia
7.4%inclusion2 decks27 decks
7%synergy
Oversold Cemetery
7.4%inclusion2 decks27 decks
2%synergy
Planeswalkers
Liliana of the Dark Realms
22%inclusion6 decks27 decks
8%synergy
Ob Nixilis, the Hate-Twisted
19%inclusion5 decks27 decks
16%synergy
Ob Nixilis Reignited
11%inclusion3 decks27 decks
9%synergy
Ugin, the Spirit Dragon
11%inclusion3 decks27 decks
11%synergy
Ob Nixilis of the Black Oath
7.4%inclusion2 decks27 decks
6%synergy
Utility Lands
Cabal Coffers
63%inclusion17 decks27 decks
8%synergy
Urborg, Tomb of Yawgmoth
59%inclusion16 decks27 decks
22%synergy
Cabal Stronghold
41%inclusion11 decks27 decks
6%synergy
The Dross Pits
41%inclusion11 decks27 decks
39%synergy
Reliquary Tower
41%inclusion11 decks27 decks
10%synergy
Geier Reach Sanitarium
33%inclusion9 decks27 decks
22%synergy
Karn's Bastion
33%inclusion9 decks27 decks
29%synergy
Susur Secundi, Void Altar
33%inclusion1 decks3 decks
26%synergy
Mikokoro, Center of the Sea
30%inclusion8 decks27 decks
27%synergy
Shizo, Death's Storehouse
26%inclusion7 decks27 decks
16%synergy
War Room
26%inclusion7 decks27 decks
10%synergy
Nykthos, Shrine to Nyx
26%inclusion7 decks27 decks
-4%synergy
Rogue's Passage
26%inclusion7 decks27 decks
7%synergy
Phyrexian Tower
22%inclusion6 decks27 decks
-3%synergy
Bojuka Bog
19%inclusion5 decks27 decks
-28%synergy
Inkmoth Nexus
19%inclusion5 decks27 decks
18%synergy
Minas Morgul, Dark Fortress
19%inclusion5 decks27 decks
16%synergy
Takenuma, Abandoned Mire
19%inclusion5 decks27 decks
3%synergy
The Monumental Facade
15%inclusion4 decks27 decks
15%synergy
Command Beacon
15%inclusion4 decks27 decks
7%synergy
Deserted Temple
15%inclusion4 decks27 decks
11%synergy
Thespian's Stage
15%inclusion4 decks27 decks
10%synergy
Trenchpost
11%inclusion3 decks27 decks
11%synergy
Crypt of Agadeem
11%inclusion3 decks27 decks
0%synergy
Glimmerpost
11%inclusion3 decks27 decks
11%synergy
Phyrexia's Core
11%inclusion3 decks27 decks
11%synergy
Castle Locthwain
11%inclusion3 decks27 decks
-6%synergy
Dark Depths
11%inclusion3 decks27 decks
10%synergy
Temple of the False God
11%inclusion3 decks27 decks
3%synergy
Access Tunnel
11%inclusion3 decks27 decks
8%synergy
Cloudpost
11%inclusion3 decks27 decks
11%synergy
Vault of Whispers
7.4%inclusion2 decks27 decks
2%synergy
Mortuary Mire
7.4%inclusion2 decks27 decks
-6%synergy
Buried Ruin
7.4%inclusion2 decks27 decks
2%synergy
Strip Mine
7.4%inclusion2 decks27 decks
5%synergy
Hidden Necropolis
7.4%inclusion2 decks27 decks
6%synergy
Mana Artifacts
Sol Ring
85%inclusion23 decks27 decks
-1%synergy
Arcane Signet
52%inclusion14 decks27 decks
-10%synergy
The Soul Stone
50%inclusion1 decks2 decks
35%synergy
Glistening Sphere
48%inclusion13 decks27 decks
47%synergy
Phyrexian Atlas
44%inclusion12 decks27 decks
44%synergy
Staff of Compleation
33%inclusion9 decks27 decks
32%synergy
Throne of Eldraine
22%inclusion6 decks27 decks
12%synergy
Mox Amber
19%inclusion5 decks27 decks
14%synergy
Commander's Sphere
15%inclusion4 decks27 decks
6%synergy
Charcoal Diamond
15%inclusion4 decks27 decks
-7%synergy
Chromatic Lantern
15%inclusion4 decks27 decks
14%synergy
Thought Vessel
15%inclusion4 decks27 decks
-11%synergy
Mind Stone
15%inclusion4 decks27 decks
-14%synergy
Nyx Lotus
11%inclusion3 decks27 decks
5%synergy
Decanter of Endless Water
7.4%inclusion2 decks27 decks
5%synergy
Fellwar Stone
7.4%inclusion2 decks27 decks
-7%synergy
Mox Tantalite
7.4%inclusion2 decks27 decks
7%synergy
Lands
Swamp
100%inclusion27 decks27 decks
5%synergy
The Seedcore
26%inclusion7 decks27 decks
26%synergy
Mirrex
26%inclusion7 decks27 decks
25%synergy
Plaza of Heroes
19%inclusion5 decks27 decks
18%synergy
The Mycosynth Gardens
15%inclusion4 decks27 decks
14%synergy
Command Tower
15%inclusion4 decks27 decks
9%synergy
Fell the Profane
11%inclusion3 decks27 decks
-8%synergy
Myriad Landscape
11%inclusion3 decks27 decks
-14%synergy
Boggart Trawler
11%inclusion3 decks27 decks
2%synergy
Malakir Rebirth
11%inclusion3 decks27 decks
-12%synergy
Terramorphic Expanse
7.4%inclusion2 decks27 decks
5%synergy
Urza's Cave
7.4%inclusion2 decks27 decks
-1%synergy
Verdant Catacombs
7.4%inclusion2 decks27 decks
4%synergy
Cavern of Souls
7.4%inclusion2 decks27 decks
1%synergy
Evolving Wilds
7.4%inclusion2 decks27 decks
4%synergy
Snow-Covered Swamp
7.4%inclusion2 decks27 decks
1%synergy
Marsh Flats
7.4%inclusion2 decks27 decks
4%synergy
Polluted Delta
7.4%inclusion2 decks27 decks
4%synergy
Bloodstained Mire
7.4%inclusion2 decks27 decks
4%synergy
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