Sheoldred, the Apocalypse (Commander) - Infect

Sheoldred, the Apocalypse
Rank #180
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Zoe Ley
Apr 14, 2026
Zoe Ley
The 10 Best Prepared Cards in Secrets of Strixhaven
The new prepared mechanic from Secrets of Strixhaven looks like it'll have some very strong cards for Commander. But which ones are the best?
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Skithiryx, the Blight Dragon
65%inclusion17 decks26 decks
64%synergy
Bilious Skulldweller
62%inclusion16 decks26 decks
61%synergy
Vraska, Betrayal's Sting
58%inclusion15 decks26 decks
55%synergy
Vraska's Fall
54%inclusion14 decks26 decks
51%synergy
Blightbelly Rat
54%inclusion14 decks26 decks
50%synergy
Plague Stinger
50%inclusion13 decks26 decks
49%synergy
Phyrexian Obliterator
58%inclusion15 decks26 decks
47%synergy
Caress of Phyrexia
42%inclusion11 decks26 decks
42%synergy
Infectious Inquiry
42%inclusion11 decks26 decks
40%synergy
Ichorclaw Myr
38%inclusion10 decks26 decks
38%synergy
Top Cards
Dark Ritual
73%inclusion19 decks26 decks
6%synergy
Phyrexian Arena
62%inclusion16 decks26 decks
22%synergy
Sign in Blood
58%inclusion15 decks26 decks
23%synergy
Jet Medallion
54%inclusion14 decks26 decks
-8%synergy
K'rrik, Son of Yawgmoth
50%inclusion13 decks26 decks
31%synergy
Peer into the Abyss
46%inclusion12 decks26 decks
36%synergy
Toxic Deluge
46%inclusion12 decks26 decks
9%synergy
Sheoldred's Edict
42%inclusion11 decks26 decks
27%synergy
Sheoldred, Whispering One
42%inclusion11 decks26 decks
31%synergy
Scrawling Crawler
38%inclusion5 decks13 decks
35%synergy
Game Changers
Demonic Tutor
42%inclusion11 decks26 decks
15%synergy
Vampiric Tutor
35%inclusion9 decks26 decks
14%synergy
Ancient Tomb
27%inclusion7 decks26 decks
15%synergy
The One Ring
27%inclusion7 decks26 decks
18%synergy
Orcish Bowmasters
27%inclusion7 decks26 decks
14%synergy
Bolas's Citadel
23%inclusion6 decks26 decks
-5%synergy
Mana Vault
15%inclusion4 decks26 decks
9%synergy
Imperial Seal
12%inclusion3 decks26 decks
5%synergy
Chrome Mox
12%inclusion3 decks26 decks
6%synergy
Creatures
Psychosis Crawler
38%inclusion10 decks26 decks
35%synergy
Phyrexian Crusader
38%inclusion10 decks26 decks
38%synergy
Gixian Puppeteer
38%inclusion10 decks26 decks
35%synergy
Ichor Rats
38%inclusion10 decks26 decks
36%synergy
Whispering Specter
35%inclusion9 decks26 decks
34%synergy
Pestilent Syphoner
35%inclusion9 decks26 decks
34%synergy
Plague Myr
35%inclusion9 decks26 decks
33%synergy
Drivnod, Carnage Dominus
35%inclusion9 decks26 decks
27%synergy
Vito, Thorn of the Dusk Rose
35%inclusion9 decks26 decks
24%synergy
Massacre Wurm
35%inclusion9 decks26 decks
17%synergy
Hand of the Praetors
35%inclusion9 decks26 decks
34%synergy
Seizan, Perverter of Truth
31%inclusion8 decks26 decks
27%synergy
Reaper of Sheoldred
31%inclusion8 decks26 decks
30%synergy
Bloodletter of Aclazotz
31%inclusion8 decks26 decks
20%synergy
Crypt Ghast
31%inclusion8 decks26 decks
-17%synergy
Sheoldred's Headcleaver
31%inclusion8 decks26 decks
30%synergy
Vraan, Executioner Thane
31%inclusion8 decks26 decks
28%synergy
Defiler of Flesh
27%inclusion7 decks26 decks
23%synergy
Grafted Butcher
27%inclusion7 decks26 decks
27%synergy
Sheoldred
27%inclusion7 decks26 decks
21%synergy
Dauthi Voidwalker
27%inclusion7 decks26 decks
11%synergy
Unstoppable Slasher
26%inclusion5 decks19 decks
21%synergy
Core Prowler
23%inclusion6 decks26 decks
23%synergy
Zenith Chronicler
23%inclusion6 decks26 decks
22%synergy
Yawgmoth, Thran Physician
23%inclusion6 decks26 decks
13%synergy
Nimraiser Paladin
23%inclusion6 decks26 decks
23%synergy
Gulping Scraptrap
23%inclusion6 decks26 decks
23%synergy
Bloodthirsty Conqueror
23%inclusion3 decks13 decks
14%synergy
Contagious Nim
19%inclusion5 decks26 decks
19%synergy
Magus of the Coffers
19%inclusion5 decks26 decks
13%synergy
Flensermite
19%inclusion5 decks26 decks
19%synergy
Scheming Aspirant
19%inclusion5 decks26 decks
19%synergy
Phyrexian Rager
19%inclusion5 decks26 decks
19%synergy
Kinzu of the Bleak Coven
19%inclusion5 decks26 decks
19%synergy
Blightsteel Colossus
19%inclusion5 decks26 decks
19%synergy
Dread Presence
15%inclusion4 decks26 decks
2%synergy
Gray Merchant of Asphodel
15%inclusion4 decks26 decks
-35%synergy
Cruel Grimnarch
15%inclusion4 decks26 decks
15%synergy
Myr Convert
15%inclusion4 decks26 decks
15%synergy
Kozilek, Butcher of Truth
15%inclusion4 decks26 decks
15%synergy
Marauding Blight-Priest
15%inclusion4 decks26 decks
8%synergy
Corpse Cur
15%inclusion4 decks26 decks
15%synergy
Septic Rats
15%inclusion4 decks26 decks
14%synergy
Testament Bearer
15%inclusion4 decks26 decks
15%synergy
Phyrexian Fleshgorger
15%inclusion4 decks26 decks
15%synergy
Enduring Tenacity
12%inclusion3 decks25 decks
4%synergy
Master of the Feast
12%inclusion3 decks26 decks
9%synergy
Evolved Sleeper
12%inclusion3 decks26 decks
11%synergy
Witch-king of Angmar
12%inclusion3 decks26 decks
10%synergy
Filth
12%inclusion3 decks26 decks
9%synergy
Instants
Black Sun's Twilight
31%inclusion8 decks26 decks
28%synergy
Withering Torment
26%inclusion5 decks19 decks
-5%synergy
Archenemy's Charm
25%inclusion1 decks4 decks
16%synergy
Whisper of the Dross
23%inclusion6 decks26 decks
20%synergy
Murder
23%inclusion6 decks26 decks
13%synergy
Blood Pact
23%inclusion6 decks26 decks
19%synergy
Deadly Rollick
19%inclusion5 decks26 decks
-5%synergy
Go for the Throat
19%inclusion5 decks26 decks
-4%synergy
Tainted Strike
19%inclusion5 decks26 decks
16%synergy
Baleful Mastery
19%inclusion5 decks26 decks
11%synergy
Dismember
19%inclusion5 decks26 decks
9%synergy
Anoint with Affliction
15%inclusion4 decks26 decks
15%synergy
Grim Affliction
15%inclusion4 decks26 decks
14%synergy
Defile
15%inclusion4 decks26 decks
-20%synergy
Darkness
15%inclusion4 decks26 decks
5%synergy
Fell the Profane
12%inclusion3 decks26 decks
-8%synergy
Village Rites
12%inclusion3 decks26 decks
-14%synergy
Virulent Wound
12%inclusion3 decks26 decks
11%synergy
Infernal Grasp
12%inclusion3 decks26 decks
-14%synergy
Malakir Rebirth
12%inclusion3 decks26 decks
-12%synergy
Offer Immortality
12%inclusion3 decks26 decks
10%synergy
Feign Death
12%inclusion3 decks26 decks
3%synergy
Geth's Verdict
7.7%inclusion2 decks26 decks
7%synergy
Entomb
7.7%inclusion2 decks26 decks
-5%synergy
Imp's Mischief
7.7%inclusion2 decks26 decks
-17%synergy
Songs of the Damned
7.7%inclusion2 decks26 decks
2%synergy
Doom Blade
7.7%inclusion2 decks26 decks
1%synergy
Cabal Ritual
7.7%inclusion2 decks26 decks
-11%synergy
Supernatural Stamina
7.7%inclusion2 decks26 decks
0%synergy
Corrupted Conviction
7.7%inclusion2 decks26 decks
-5%synergy
Sorceries
Insatiable Avarice
35%inclusion9 decks26 decks
23%synergy
Night's Whisper
31%inclusion8 decks26 decks
6%synergy
Black Sun's Zenith
27%inclusion7 decks26 decks
22%synergy
Damnable Pact
27%inclusion7 decks26 decks
23%synergy
Feed the Infection
27%inclusion7 decks26 decks
26%synergy
Feed the Swarm
27%inclusion7 decks26 decks
-23%synergy
Dark Deal
27%inclusion7 decks26 decks
16%synergy
Damnation
27%inclusion7 decks26 decks
7%synergy
Vat Emergence
23%inclusion6 decks26 decks
22%synergy
Monumental Corruption
23%inclusion6 decks26 decks
22%synergy
Phyresis Outbreak
23%inclusion6 decks26 decks
21%synergy
Drown in Ichor
23%inclusion6 decks26 decks
19%synergy
Rush of Dread
19%inclusion5 decks26 decks
16%synergy
Torment of Hailfire
19%inclusion5 decks26 decks
4%synergy
Reanimate
19%inclusion5 decks26 decks
-21%synergy
Geth's Summons
19%inclusion5 decks26 decks
19%synergy
Beseech the Mirror
19%inclusion5 decks26 decks
12%synergy
Mutilate
15%inclusion4 decks26 decks
-1%synergy
Mind Twist
15%inclusion4 decks26 decks
14%synergy
Exsanguinate
15%inclusion4 decks26 decks
-9%synergy
Annihilating Glare
15%inclusion4 decks26 decks
14%synergy
Grim Tutor
15%inclusion4 decks26 decks
4%synergy
Life's Finale
12%inclusion3 decks26 decks
11%synergy
Diabolic Tutor
12%inclusion3 decks26 decks
-3%synergy
Bubbling Muck
12%inclusion3 decks26 decks
-4%synergy
Read the Bones
12%inclusion3 decks26 decks
-5%synergy
In Garruk's Wake
12%inclusion3 decks26 decks
8%synergy
Invoke Despair
12%inclusion3 decks26 decks
9%synergy
Cruelclaw's Heist
8.3%inclusion2 decks24 decks
6%synergy
Diabolic Intent
7.7%inclusion2 decks26 decks
-7%synergy
Spread the Sickness
7.7%inclusion2 decks26 decks
7%synergy
Eldritch Pact
7.7%inclusion2 decks26 decks
7%synergy
Disentomb
7.7%inclusion2 decks26 decks
7%synergy
Rise of the Dark Realms
7.7%inclusion2 decks26 decks
-5%synergy
Demonic Counsel
5.3%inclusion1 decks19 decks
2%synergy
Utility Artifacts
Swiftfoot Boots
38%inclusion10 decks26 decks
7%synergy
Teferi's Puzzle Box
31%inclusion8 decks26 decks
28%synergy
Lightning Greaves
31%inclusion8 decks26 decks
-3%synergy
Howling Mine
31%inclusion8 decks26 decks
27%synergy
Temple Bell
27%inclusion7 decks26 decks
25%synergy
Grafted Exoskeleton
23%inclusion6 decks26 decks
22%synergy
The Darkness Crystal
20%inclusion1 decks5 decks
-0%synergy
Mithril Coat
19%inclusion5 decks26 decks
14%synergy
Contagion Clasp
19%inclusion5 decks26 decks
17%synergy
Contagion Engine
19%inclusion5 decks26 decks
17%synergy
Aetherflux Reservoir
19%inclusion5 decks26 decks
10%synergy
Helm of Obedience
15%inclusion4 decks26 decks
15%synergy
Font of Mythos
15%inclusion4 decks26 decks
13%synergy
Mindcrank
15%inclusion4 decks26 decks
10%synergy
Alhammarret's Archive
15%inclusion4 decks26 decks
12%synergy
Amulet of Vigor
15%inclusion4 decks26 decks
15%synergy
Vat of Rebirth
12%inclusion3 decks26 decks
8%synergy
Portal to Phyrexia
12%inclusion3 decks26 decks
10%synergy
Shadowspear
12%inclusion3 decks26 decks
7%synergy
Commander's Plate
12%inclusion3 decks26 decks
6%synergy
Dross Skullbomb
7.7%inclusion2 decks26 decks
7%synergy
Sensei's Divining Top
7.7%inclusion2 decks26 decks
-0%synergy
Wayfarer's Bauble
7.7%inclusion2 decks26 decks
-7%synergy
Shrine of Limitless Power
7.7%inclusion2 decks26 decks
8%synergy
Prosthetic Injector
7.7%inclusion2 decks26 decks
7%synergy
Bontu's Monument
7.7%inclusion2 decks26 decks
-21%synergy
Whispersilk Cloak
7.7%inclusion2 decks26 decks
2%synergy
Endless Atlas
7.7%inclusion2 decks26 decks
5%synergy
Black Vise
7.7%inclusion2 decks26 decks
7%synergy
Monument to Perfection
7.7%inclusion2 decks26 decks
8%synergy
Decimator Web
7.7%inclusion2 decks26 decks
8%synergy
Enchantments
Underworld Dreams
38%inclusion10 decks26 decks
33%synergy
Sanguine Bond
35%inclusion9 decks26 decks
23%synergy
Black Market Connections
35%inclusion9 decks26 decks
10%synergy
Necrogen Communion
35%inclusion9 decks26 decks
33%synergy
Exquisite Blood
31%inclusion8 decks26 decks
18%synergy
Glistening Oil
27%inclusion7 decks26 decks
26%synergy
The Meathook Massacre
23%inclusion6 decks26 decks
6%synergy
Phyresis
19%inclusion5 decks26 decks
17%synergy
Call of the Ring
19%inclusion5 decks26 decks
17%synergy
No Mercy
19%inclusion5 decks26 decks
12%synergy
Grievous Wound
16%inclusion3 decks19 decks
14%synergy
Greed
12%inclusion3 decks26 decks
5%synergy
Blowfly Infestation
12%inclusion3 decks26 decks
10%synergy
Enslave
12%inclusion3 decks26 decks
11%synergy
Necrodominance
12%inclusion3 decks26 decks
9%synergy
Wound Reflection
12%inclusion3 decks26 decks
8%synergy
Dauthi Embrace
12%inclusion3 decks26 decks
10%synergy
Painful Quandary
12%inclusion3 decks26 decks
1%synergy
Revel in Riches
12%inclusion3 decks26 decks
7%synergy
Bloodchief Ascension
12%inclusion3 decks26 decks
2%synergy
Leyline of the Void
12%inclusion3 decks26 decks
10%synergy
Waste Not
7.7%inclusion2 decks26 decks
-3%synergy
Polluted Bonds
7.7%inclusion2 decks26 decks
6%synergy
Black Market
7.7%inclusion2 decks26 decks
-13%synergy
The Cruelty of Gix
7.7%inclusion2 decks26 decks
6%synergy
Crumbling Ashes
7.7%inclusion2 decks26 decks
7%synergy
Evil Presence
7.7%inclusion2 decks26 decks
8%synergy
Phyrexian Reclamation
7.7%inclusion2 decks26 decks
-2%synergy
Grave Pact
7.7%inclusion2 decks26 decks
-12%synergy
Dictate of Erebos
7.7%inclusion2 decks26 decks
-3%synergy
Liliana's Caress
7.7%inclusion2 decks26 decks
2%synergy
Kaya's Ghostform
7.7%inclusion2 decks26 decks
-2%synergy
Gate to Phyrexia
7.7%inclusion2 decks26 decks
7%synergy
Oversold Cemetery
7.7%inclusion2 decks26 decks
2%synergy
Planeswalkers
Liliana of the Dark Realms
23%inclusion6 decks26 decks
9%synergy
Ob Nixilis, the Hate-Twisted
19%inclusion5 decks26 decks
17%synergy
Ob Nixilis Reignited
12%inclusion3 decks26 decks
9%synergy
Ugin, the Spirit Dragon
12%inclusion3 decks26 decks
11%synergy
Karn, the Great Creator
7.7%inclusion2 decks26 decks
7%synergy
Ob Nixilis of the Black Oath
7.7%inclusion2 decks26 decks
7%synergy
Utility Lands
Cabal Coffers
62%inclusion16 decks26 decks
7%synergy
Urborg, Tomb of Yawgmoth
54%inclusion14 decks26 decks
16%synergy
Cabal Stronghold
38%inclusion10 decks26 decks
4%synergy
Reliquary Tower
38%inclusion10 decks26 decks
8%synergy
The Dross Pits
35%inclusion9 decks26 decks
33%synergy
Karn's Bastion
35%inclusion9 decks26 decks
31%synergy
Geier Reach Sanitarium
31%inclusion8 decks26 decks
20%synergy
Shizo, Death's Storehouse
27%inclusion7 decks26 decks
17%synergy
Nykthos, Shrine to Nyx
27%inclusion7 decks26 decks
-3%synergy
Mikokoro, Center of the Sea
27%inclusion7 decks26 decks
24%synergy
Rogue's Passage
27%inclusion7 decks26 decks
8%synergy
Susur Secundi, Void Altar
25%inclusion1 decks4 decks
18%synergy
Phyrexian Tower
23%inclusion6 decks26 decks
-3%synergy
War Room
23%inclusion6 decks26 decks
7%synergy
Inkmoth Nexus
19%inclusion5 decks26 decks
18%synergy
Minas Morgul, Dark Fortress
19%inclusion5 decks26 decks
16%synergy
Takenuma, Abandoned Mire
19%inclusion5 decks26 decks
4%synergy
Bojuka Bog
15%inclusion4 decks26 decks
-32%synergy
The Monumental Facade
15%inclusion4 decks26 decks
15%synergy
Command Beacon
15%inclusion4 decks26 decks
7%synergy
Glimmerpost
15%inclusion4 decks26 decks
15%synergy
Deserted Temple
15%inclusion4 decks26 decks
11%synergy
Thespian's Stage
15%inclusion4 decks26 decks
10%synergy
Cloudpost
15%inclusion4 decks26 decks
15%synergy
Vault of Whispers
12%inclusion3 decks26 decks
6%synergy
Buried Ruin
12%inclusion3 decks26 decks
7%synergy
Trenchpost
12%inclusion3 decks26 decks
11%synergy
Crypt of Agadeem
12%inclusion3 decks26 decks
0%synergy
Phyrexia's Core
12%inclusion3 decks26 decks
11%synergy
Castle Locthwain
12%inclusion3 decks26 decks
-5%synergy
Dark Depths
12%inclusion3 decks26 decks
11%synergy
Temple of the False God
12%inclusion3 decks26 decks
4%synergy
Access Tunnel
12%inclusion3 decks26 decks
9%synergy
Mortuary Mire
7.7%inclusion2 decks26 decks
-5%synergy
Memorial to Folly
7.7%inclusion2 decks26 decks
5%synergy
Strip Mine
7.7%inclusion2 decks26 decks
5%synergy
Hidden Necropolis
7.7%inclusion2 decks26 decks
6%synergy
Mana Artifacts
Sol Ring
88%inclusion23 decks26 decks
3%synergy
Arcane Signet
54%inclusion14 decks26 decks
-8%synergy
Glistening Sphere
50%inclusion13 decks26 decks
49%synergy
Phyrexian Atlas
38%inclusion10 decks26 decks
38%synergy
Staff of Compleation
35%inclusion9 decks26 decks
33%synergy
The Soul Stone
33%inclusion1 decks3 decks
18%synergy
Throne of Eldraine
23%inclusion6 decks26 decks
14%synergy
Mox Amber
19%inclusion5 decks26 decks
15%synergy
Commander's Sphere
15%inclusion4 decks26 decks
7%synergy
Charcoal Diamond
15%inclusion4 decks26 decks
-7%synergy
Chromatic Lantern
15%inclusion4 decks26 decks
15%synergy
Mind Stone
15%inclusion4 decks26 decks
-13%synergy
Thought Vessel
12%inclusion3 decks26 decks
-14%synergy
Nyx Lotus
12%inclusion3 decks26 decks
5%synergy
Decanter of Endless Water
7.7%inclusion2 decks26 decks
5%synergy
Fellwar Stone
7.7%inclusion2 decks26 decks
-6%synergy
Thran Dynamo
7.7%inclusion2 decks26 decks
2%synergy
Mox Tantalite
7.7%inclusion2 decks26 decks
7%synergy
Lands
Swamp
100%inclusion26 decks26 decks
5%synergy
The Seedcore
27%inclusion7 decks26 decks
27%synergy
Mirrex
23%inclusion6 decks26 decks
22%synergy
The Mycosynth Gardens
19%inclusion5 decks26 decks
18%synergy
Plaza of Heroes
19%inclusion5 decks26 decks
18%synergy
Command Tower
15%inclusion4 decks26 decks
10%synergy
Fell the Profane
12%inclusion3 decks26 decks
-8%synergy
Myriad Landscape
12%inclusion3 decks26 decks
-14%synergy
Urza's Cave
12%inclusion3 decks26 decks
3%synergy
Boggart Trawler
12%inclusion3 decks26 decks
2%synergy
Malakir Rebirth
12%inclusion3 decks26 decks
-12%synergy
Terramorphic Expanse
7.7%inclusion2 decks26 decks
5%synergy
Verdant Catacombs
7.7%inclusion2 decks26 decks
4%synergy
Cavern of Souls
7.7%inclusion2 decks26 decks
1%synergy
Evolving Wilds
7.7%inclusion2 decks26 decks
4%synergy
Snow-Covered Swamp
7.7%inclusion2 decks26 decks
1%synergy
Marsh Flats
7.7%inclusion2 decks26 decks
4%synergy
Polluted Delta
7.7%inclusion2 decks26 decks
4%synergy
Bloodstained Mire
7.7%inclusion2 decks26 decks
4%synergy
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