Virtus the Veiled + Archfiend of Despair

Virtus the Veiled
Archfiend of Despair

Requires
Virtus the Veiled must be on the battlefield. Archfiend of Despair must be on the battlefield. Virtus does not have summoning sickness. An opponent is unable to block and kill Virtus.
Steps
  1. Deal combat damage to an opponent with Virtus.
  2. Virtus triggers, causing the opponent to lose half their life total, rounded up.
  3. At the beginning of your end step, Archfiend of Despair triggers, causing the opponent to lose life equal to the life they lost this turn.
  4. The opponent loses the game due to having zero or less life.
Results
Near-infinite lifeloss for target opponent. Target opponent loses the game.