Sephiroth, the Savior (Commander) - Expensive Infect

Original Name:

Atraxa, Grand UnifierAtraxa, Grand Unifier

Sephiroth, the Savior
Rank #73
65decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Atraxa, Praetors' Voice
65%inclusion42 decks65 decks
61%synergy
Prologue to Phyresis
85%inclusion55 decks65 decks
60%synergy
Phyresis Outbreak
75%inclusion49 decks65 decks
57%synergy
Skrelv, Defector Mite
75%inclusion49 decks65 decks
56%synergy
Venerated Rotpriest
74%inclusion48 decks65 decks
53%synergy
Vraska's Fall
75%inclusion49 decks65 decks
53%synergy
Infectious Inquiry
75%inclusion49 decks65 decks
53%synergy
Ixhel, Scion of Atraxa
71%inclusion46 decks65 decks
52%synergy
Infectious Bite
65%inclusion42 decks65 decks
47%synergy
Elesh Norn, Mother of Machines
57%inclusion37 decks65 decks
44%synergy
Top Cards
Tekuthal, Inquiry Dominus
68%inclusion44 decks65 decks
30%synergy
Vraska, Betrayal's Sting
66%inclusion43 decks65 decks
35%synergy
Vorinclex, Monstrous Raider
62%inclusion40 decks65 decks
36%synergy
Bloated Contaminator
60%inclusion39 decks65 decks
39%synergy
Swords to Plowshares
60%inclusion39 decks65 decks
1%synergy
Farseek
58%inclusion38 decks65 decks
19%synergy
Contaminant Grafter
55%inclusion36 decks65 decks
39%synergy
Thrummingbird
55%inclusion36 decks65 decks
24%synergy
Vishgraz, the Doomhive
54%inclusion35 decks65 decks
41%synergy
Ezuri, Stalker of Spheres
54%inclusion35 decks65 decks
22%synergy
Game Changers
Smothering Tithe
55%inclusion36 decks65 decks
21%synergy
Rhystic Study
55%inclusion36 decks65 decks
14%synergy
Cyclonic Rift
48%inclusion31 decks65 decks
13%synergy
Demonic Tutor
42%inclusion27 decks65 decks
6%synergy
Teferi's Protection
40%inclusion26 decks65 decks
21%synergy
Vampiric Tutor
32%inclusion21 decks65 decks
3%synergy
The One Ring
28%inclusion18 decks65 decks
6%synergy
Fierce Guardianship
25%inclusion16 decks65 decks
1%synergy
Ancient Tomb
22%inclusion14 decks65 decks
1%synergy
Enlightened Tutor
22%inclusion14 decks65 decks
-4%synergy
Creatures
Skithiryx, the Blight Dragon
49%inclusion32 decks65 decks
35%synergy
Cankerbloom
48%inclusion31 decks65 decks
27%synergy
Elesh Norn, Grand Cenobite
45%inclusion29 decks65 decks
37%synergy
Ichor Rats
43%inclusion28 decks65 decks
24%synergy
Metastatic Evangel
40%inclusion20 decks50 decks
23%synergy
Evolution Sage
40%inclusion26 decks65 decks
5%synergy
Birds of Paradise
40%inclusion26 decks65 decks
-3%synergy
Blighted Agent
40%inclusion26 decks65 decks
23%synergy
Phyrexian Censor
38%inclusion25 decks65 decks
32%synergy
Sheoldred
38%inclusion25 decks65 decks
33%synergy
Elesh Norn
35%inclusion23 decks65 decks
29%synergy
Tyrranax Rex
35%inclusion23 decks65 decks
26%synergy
Brimaz, Blight of Oreskos
35%inclusion23 decks65 decks
29%synergy
Jin-Gitaxias, Progress Tyrant
35%inclusion23 decks65 decks
32%synergy
Sheoldred, Whispering One
34%inclusion22 decks65 decks
29%synergy
Jin-Gitaxias
34%inclusion22 decks65 decks
29%synergy
Norn's Choirmaster
34%inclusion22 decks65 decks
21%synergy
Sheoldred, the Apocalypse
31%inclusion20 decks65 decks
26%synergy
Blightbelly Rat
31%inclusion20 decks65 decks
16%synergy
Vorinclex, Voice of Hunger
31%inclusion20 decks65 decks
27%synergy
Necrogen Rotpriest
29%inclusion19 decks65 decks
19%synergy
Delighted Halfling
29%inclusion19 decks65 decks
4%synergy
Y'shtola Rhul
29%inclusion2 decks7 decks
25%synergy
Plague Myr
28%inclusion18 decks65 decks
19%synergy
Phyrexian Metamorph
28%inclusion18 decks65 decks
17%synergy
Roaming Throne
28%inclusion18 decks65 decks
24%synergy
Bloom Tender
26%inclusion17 decks65 decks
3%synergy
Tainted Observer
26%inclusion17 decks65 decks
11%synergy
Phyrexian Swarmlord
26%inclusion17 decks65 decks
14%synergy
Glissa Sunslayer
26%inclusion17 decks65 decks
22%synergy
Vorinclex
25%inclusion16 decks65 decks
21%synergy
Myr Convert
23%inclusion15 decks65 decks
15%synergy
Voidwing Hybrid
22%inclusion14 decks65 decks
6%synergy
Esper Sentinel
22%inclusion14 decks65 decks
-8%synergy
Glissa, Herald of Predation
22%inclusion14 decks65 decks
16%synergy
Zopandrel, Hunger Dominus
20%inclusion13 decks65 decks
17%synergy
Jin-Gitaxias, Core Augur
20%inclusion13 decks65 decks
17%synergy
Phyrexian Obliterator
18%inclusion12 decks65 decks
16%synergy
Flux Channeler
18%inclusion12 decks65 decks
-4%synergy
Gix, Yawgmoth Praetor
18%inclusion12 decks65 decks
17%synergy
Displacer Kitten
17%inclusion11 decks65 decks
3%synergy
Noble Hierarch
17%inclusion11 decks65 decks
-10%synergy
Bloodroot Apothecary
16%inclusion7 decks45 decks
10%synergy
Plague Stinger
15%inclusion10 decks65 decks
3%synergy
Blightsteel Colossus
15%inclusion10 decks65 decks
12%synergy
Virulent Silencer
14%inclusion1 decks7 decks
14%synergy
Patrolling Peacemaker
14%inclusion1 decks7 decks
7%synergy
Surge Conductor
14%inclusion1 decks7 decks
13%synergy
Dreamtide Whale
14%inclusion7 decks50 decks
-4%synergy
Phyrexian Vindicator
14%inclusion9 decks65 decks
11%synergy
Instants
Mana Drain
48%inclusion31 decks65 decks
29%synergy
Experimental Augury
38%inclusion25 decks65 decks
18%synergy
Ephemerate
35%inclusion23 decks65 decks
24%synergy
Counterspell
35%inclusion23 decks65 decks
4%synergy
Path to Exile
32%inclusion21 decks65 decks
1%synergy
Heroic Intervention
31%inclusion20 decks65 decks
14%synergy
Tainted Strike
28%inclusion18 decks65 decks
20%synergy
Assassin's Trophy
22%inclusion14 decks65 decks
2%synergy
Swan Song
20%inclusion13 decks65 decks
-5%synergy
Anguished Unmaking
20%inclusion13 decks65 decks
8%synergy
Force of Will
18%inclusion12 decks65 decks
-3%synergy
Dark Ritual
17%inclusion11 decks65 decks
1%synergy
Arcane Denial
17%inclusion11 decks65 decks
8%synergy
Worldly Tutor
17%inclusion11 decks65 decks
-1%synergy
Whisper of the Dross
15%inclusion10 decks65 decks
9%synergy
Beast Within
15%inclusion10 decks65 decks
4%synergy
Radstorm
15%inclusion10 decks65 decks
6%synergy
An Offer You Can't Refuse
14%inclusion9 decks65 decks
-8%synergy
Dawn's Truce
13%inclusion6 decks46 decks
11%synergy
Noxious Revival
12%inclusion8 decks65 decks
4%synergy
Mystical Tutor
12%inclusion8 decks65 decks
-2%synergy
Atomize
11%inclusion7 decks63 decks
-1%synergy
Cloudshift
9.2%inclusion6 decks65 decks
3%synergy
Ghostly Flicker
9.2%inclusion6 decks65 decks
3%synergy
Force of Negation
9.2%inclusion6 decks65 decks
-9%synergy
Eerie Interlude
7.7%inclusion5 decks65 decks
2%synergy
Dovin's Veto
7.7%inclusion5 decks65 decks
-3%synergy
Reject Imperfection
7.7%inclusion5 decks65 decks
0%synergy
Brokers Confluence
7.7%inclusion5 decks65 decks
1%synergy
Deadly Rollick
6.2%inclusion4 decks65 decks
-6%synergy
Abrupt Decay
6.2%inclusion4 decks65 decks
-8%synergy
Flawless Maneuver
6.2%inclusion4 decks65 decks
4%synergy
Momentary Blink
6.2%inclusion4 decks65 decks
2%synergy
Pact of Negation
6.2%inclusion4 decks65 decks
-11%synergy
Strix Serenade
6.0%inclusion3 decks50 decks
3%synergy
Sorceries
Unnatural Restoration
51%inclusion33 decks65 decks
31%synergy
Three Visits
46%inclusion30 decks65 decks
25%synergy
White Sun's Twilight
46%inclusion30 decks65 decks
34%synergy
Nature's Lore
42%inclusion27 decks65 decks
15%synergy
Cultivate
42%inclusion27 decks65 decks
9%synergy
Tezzeret's Gambit
40%inclusion26 decks65 decks
11%synergy
Drown in Ichor
35%inclusion23 decks65 decks
20%synergy
Expand the Sphere
31%inclusion20 decks65 decks
22%synergy
Toxic Deluge
23%inclusion15 decks65 decks
8%synergy
Triumph of the Hordes
22%inclusion14 decks65 decks
17%synergy
Thirsting Roots
22%inclusion14 decks65 decks
9%synergy
Fated Clash
20%inclusion1 decks5 decks
20%synergy
Kodama's Reach
18%inclusion12 decks65 decks
0%synergy
Farewell
17%inclusion11 decks65 decks
0%synergy
Rampant Growth
12%inclusion8 decks65 decks
-5%synergy
Geth's Summons
12%inclusion8 decks65 decks
9%synergy
Breach the Multiverse
12%inclusion8 decks65 decks
10%synergy
Sunfall
12%inclusion8 decks65 decks
7%synergy
Contentious Plan
11%inclusion7 decks65 decks
-2%synergy
Skyshroud Claim
11%inclusion7 decks65 decks
5%synergy
Reanimate
11%inclusion7 decks65 decks
3%synergy
Supreme Verdict
9.2%inclusion6 decks65 decks
-3%synergy
Vat Emergence
9.2%inclusion6 decks65 decks
3%synergy
Green Sun's Twilight
7.7%inclusion5 decks65 decks
6%synergy
Culling Ritual
7.7%inclusion5 decks65 decks
-6%synergy
Imperial Seal
6.2%inclusion4 decks65 decks
-7%synergy
Bala Ged Recovery
6.2%inclusion4 decks65 decks
3%synergy
Raise the Palisade
6.2%inclusion4 decks65 decks
6%synergy
Utility Artifacts
Realmbreaker, the Invasion Tree
34%inclusion22 decks65 decks
31%synergy
Lightning Greaves
25%inclusion16 decks65 decks
6%synergy
Urza's Incubator
20%inclusion13 decks65 decks
18%synergy
Portal to Phyrexia
17%inclusion11 decks65 decks
15%synergy
The Great Henge
15%inclusion10 decks65 decks
9%synergy
Swiftfoot Boots
15%inclusion10 decks65 decks
1%synergy
Buster Sword
14%inclusion1 decks7 decks
14%synergy
Insight Engine
14%inclusion1 decks7 decks
10%synergy
The Dominion Bracelet
14%inclusion1 decks7 decks
14%synergy
Grafted Exoskeleton
11%inclusion7 decks65 decks
6%synergy
Dragonfire Blade
10%inclusion1 decks10 decks
9%synergy
Contagion Engine
9.2%inclusion6 decks65 decks
-7%synergy
Panharmonicon
9.2%inclusion6 decks65 decks
2%synergy
Sword of Truth and Justice
9.2%inclusion6 decks65 decks
0%synergy
Ichormoon Gauntlet
7.7%inclusion5 decks65 decks
-5%synergy
Conjurer's Closet
7.7%inclusion5 decks65 decks
3%synergy
Norn's Annex
6.2%inclusion4 decks65 decks
1%synergy
Enchantments
Norn's Decree
48%inclusion31 decks65 decks
31%synergy
Skrelv's Hive
40%inclusion26 decks65 decks
29%synergy
Phyrexian Arena
35%inclusion23 decks65 decks
21%synergy
Inexorable Tide
32%inclusion21 decks65 decks
5%synergy
Mystic Remora
18%inclusion12 decks65 decks
-9%synergy
Teleportation Circle
18%inclusion12 decks65 decks
11%synergy
Necrogen Communion
18%inclusion12 decks65 decks
12%synergy
Sphere Grid
14%inclusion1 decks7 decks
11%synergy
Phyresis
14%inclusion9 decks65 decks
9%synergy
Sylvan Library
12%inclusion8 decks65 decks
2%synergy
Innkeeper's Talent
11%inclusion5 decks46 decks
-1%synergy
Brokers Ascendancy
11%inclusion7 decks65 decks
-10%synergy
Food Chain
9.2%inclusion6 decks65 decks
3%synergy
Mirari's Wake
9.2%inclusion6 decks65 decks
4%synergy
Ghostly Prison
9.2%inclusion6 decks65 decks
-1%synergy
Doubling Season
7.7%inclusion5 decks65 decks
-11%synergy
Exploration
7.7%inclusion5 decks65 decks
5%synergy
Trouble in Pairs
6.3%inclusion4 decks64 decks
4%synergy
Glistening Oil
6.2%inclusion4 decks65 decks
5%synergy
Wild Growth
6.2%inclusion4 decks65 decks
2%synergy
Corrupted Conscience
6.2%inclusion4 decks65 decks
2%synergy
Battles
Invasion of Ikoria
7.7%inclusion5 decks65 decks
3%synergy
Planeswalkers
Ajani, Sleeper Agent
32%inclusion21 decks65 decks
18%synergy
The Eternal Wanderer
18%inclusion12 decks65 decks
7%synergy
Nissa, Ascended Animist
6.2%inclusion4 decks65 decks
1%synergy
Utility Lands
Karn's Bastion
62%inclusion40 decks65 decks
26%synergy
Reliquary Tower
55%inclusion36 decks65 decks
29%synergy
Boseiju, Who Endures
37%inclusion24 decks65 decks
10%synergy
Yavimaya, Cradle of Growth
31%inclusion20 decks65 decks
17%synergy
Urborg, Tomb of Yawgmoth
28%inclusion18 decks65 decks
16%synergy
Inkmoth Nexus
25%inclusion16 decks65 decks
17%synergy
Evendo, Waking Haven
14%inclusion1 decks7 decks
12%synergy
Three Tree City
13%inclusion6 decks47 decks
12%synergy
Otawara, Soaring City
12%inclusion8 decks65 decks
-10%synergy
Cabal Coffers
11%inclusion7 decks65 decks
9%synergy
Mistrise Village
10%inclusion1 decks10 decks
0%synergy
Urza's Saga
9.2%inclusion6 decks65 decks
5%synergy
Rogue's Passage
9.2%inclusion6 decks65 decks
-2%synergy
Bojuka Bog
7.7%inclusion5 decks65 decks
-3%synergy
Mana Artifacts
Sol Ring
94%inclusion61 decks65 decks
7%synergy
Arcane Signet
83%inclusion54 decks65 decks
4%synergy
Glistening Sphere
63%inclusion41 decks65 decks
45%synergy
Chromatic Lantern
48%inclusion31 decks65 decks
11%synergy
Staff of Compleation
31%inclusion20 decks65 decks
20%synergy
Fellwar Stone
29%inclusion19 decks65 decks
-5%synergy
Thought Vessel
20%inclusion13 decks65 decks
10%synergy
Mana Crypt
15%inclusion10 decks65 decks
10%synergy
Jeweled Lotus
14%inclusion9 decks65 decks
11%synergy
Chrome Mox
14%inclusion9 decks65 decks
-5%synergy
Lotus Petal
11%inclusion7 decks65 decks
-8%synergy
Talisman of Resilience
11%inclusion7 decks65 decks
6%synergy
Talisman of Dominance
11%inclusion7 decks65 decks
2%synergy
Mana Vault
11%inclusion7 decks65 decks
-7%synergy
Mox Amber
11%inclusion7 decks65 decks
-3%synergy
Herd Heirloom
10%inclusion1 decks10 decks
9%synergy
Talisman of Curiosity
9.2%inclusion6 decks65 decks
1%synergy
Talisman of Hierarchy
9.2%inclusion6 decks65 decks
5%synergy
Mox Opal
9.2%inclusion6 decks65 decks
1%synergy
Everflowing Chalice
7.7%inclusion5 decks65 decks
-15%synergy
Astral Cornucopia
7.7%inclusion5 decks65 decks
-19%synergy
Mox Diamond
7.7%inclusion5 decks65 decks
-8%synergy
Talisman of Progress
6.2%inclusion4 decks65 decks
0%synergy
Decanter of Endless Water
6.2%inclusion4 decks65 decks
2%synergy
Phyrexian Atlas
6.2%inclusion4 decks65 decks
1%synergy
Lands
Command Tower
97%inclusion63 decks65 decks
5%synergy
Swamp
85%inclusion55 decks65 decks
9%synergy
Forest
85%inclusion55 decks65 decks
7%synergy
Breeding Pool
83%inclusion54 decks65 decks
31%synergy
Island
83%inclusion54 decks65 decks
6%synergy
Plains
82%inclusion53 decks65 decks
6%synergy
Hallowed Fountain
82%inclusion53 decks65 decks
36%synergy
Godless Shrine
78%inclusion51 decks65 decks
37%synergy
Overgrown Tomb
78%inclusion51 decks65 decks
33%synergy
Temple Garden
77%inclusion50 decks65 decks
34%synergy
Watery Grave
74%inclusion48 decks65 decks
25%synergy
Flooded Strand
71%inclusion46 decks65 decks
26%synergy
Misty Rainforest
69%inclusion45 decks65 decks
24%synergy
Windswept Heath
69%inclusion45 decks65 decks
23%synergy
Polluted Delta
69%inclusion45 decks65 decks
25%synergy
Verdant Catacombs
66%inclusion43 decks65 decks
21%synergy
Exotic Orchard
65%inclusion42 decks65 decks
-1%synergy
Marsh Flats
63%inclusion41 decks65 decks
19%synergy
Indatha Triome
60%inclusion39 decks65 decks
29%synergy
Zagoth Triome
57%inclusion37 decks65 decks
25%synergy
Spara's Headquarters
55%inclusion36 decks65 decks
24%synergy
Raffine's Tower
52%inclusion34 decks65 decks
24%synergy
Cavern of Souls
43%inclusion28 decks65 decks
32%synergy
Bountiful Promenade
40%inclusion26 decks65 decks
21%synergy
Mana Confluence
40%inclusion26 decks65 decks
10%synergy
Rejuvenating Springs
40%inclusion26 decks65 decks
16%synergy
Undergrowth Stadium
38%inclusion25 decks65 decks
18%synergy
City of Brass
38%inclusion25 decks65 decks
8%synergy
Savannah
37%inclusion24 decks65 decks
12%synergy
Tropical Island
37%inclusion24 decks65 decks
12%synergy
Vault of Champions
37%inclusion24 decks65 decks
20%synergy
Path of Ancestry
35%inclusion23 decks65 decks
11%synergy
The Seedcore
34%inclusion22 decks65 decks
24%synergy
Morphic Pool
34%inclusion22 decks65 decks
16%synergy
Tundra
32%inclusion21 decks65 decks
8%synergy
Sea of Clouds
32%inclusion21 decks65 decks
13%synergy
Reflecting Pool
32%inclusion21 decks65 decks
15%synergy
Bayou
32%inclusion21 decks65 decks
7%synergy
Underground Sea
29%inclusion19 decks65 decks
5%synergy
Scrubland
29%inclusion19 decks65 decks
5%synergy
Sandsteppe Citadel
22%inclusion14 decks65 decks
-3%synergy
Bloodstained Mire
20%inclusion13 decks65 decks
3%synergy
Arcane Sanctum
18%inclusion12 decks65 decks
-4%synergy
Arid Mesa
17%inclusion11 decks65 decks
4%synergy
Wooded Foothills
15%inclusion10 decks65 decks
-2%synergy
Scalding Tarn
15%inclusion10 decks65 decks
-4%synergy
Opulent Palace
15%inclusion10 decks65 decks
-8%synergy
Starting Town
14%inclusion1 decks7 decks
8%synergy
Seaside Citadel
14%inclusion9 decks65 decks
-9%synergy
Mirrex
14%inclusion9 decks65 decks
9%synergy
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