Sheoldred, the Apocalypse (Commander) - Optimized Lifegain

Sheoldred, the Apocalypse
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Zoe Ley
Apr 14, 2026
Zoe Ley
The 10 Best Prepared Cards in Secrets of Strixhaven
The new prepared mechanic from Secrets of Strixhaven looks like it'll have some very strong cards for Commander. But which ones are the best?
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Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
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Decorum Dissertation
33%inclusion11 decks33 decks
29%synergy
Scheming Silvertongue
31%inclusion10 decks32 decks
25%synergy
Pox Plague
6.3%inclusion2 decks32 decks
2%synergy
Withering Curse
5.1%inclusion2 decks39 decks
3%synergy
Emeritus of Woe
3.2%inclusion1 decks31 decks
-4%synergy
High Synergy Cards
Peer into the Abyss
87%inclusion134 decks154 decks
77%synergy
Teferi's Puzzle Box
79%inclusion121 decks154 decks
76%synergy
Underworld Dreams
81%inclusion124 decks154 decks
74%synergy
Howling Mine
75%inclusion115 decks154 decks
71%synergy
Vito, Thorn of the Dusk Rose
77%inclusion118 decks154 decks
66%synergy
Seizan, Perverter of Truth
68%inclusion104 decks154 decks
64%synergy
Dark Deal
71%inclusion109 decks154 decks
60%synergy
Exquisite Blood
72%inclusion111 decks154 decks
59%synergy
Scrawling Crawler
61%inclusion93 decks152 decks
57%synergy
Marauding Blight-Priest
64%inclusion98 decks154 decks
57%synergy
Top Cards
Dark Ritual
90%inclusion138 decks154 decks
23%synergy
Jet Medallion
82%inclusion127 decks154 decks
21%synergy
Phyrexian Arena
77%inclusion118 decks154 decks
37%synergy
Crypt Ghast
73%inclusion113 decks154 decks
26%synergy
Sign in Blood
72%inclusion111 decks154 decks
37%synergy
Sanguine Bond
66%inclusion101 decks154 decks
54%synergy
Toxic Deluge
62%inclusion96 decks154 decks
26%synergy
Lightning Greaves
61%inclusion94 decks154 decks
27%synergy
K'rrik, Son of Yawgmoth
61%inclusion94 decks154 decks
42%synergy
Damnable Pact
59%inclusion91 decks154 decks
55%synergy
Game Changers
Bolas's Citadel
68%inclusion104 decks154 decks
39%synergy
Demonic Tutor
68%inclusion104 decks154 decks
40%synergy
Orcish Bowmasters
64%inclusion99 decks154 decks
51%synergy
Vampiric Tutor
55%inclusion84 decks154 decks
34%synergy
The One Ring
49%inclusion76 decks154 decks
40%synergy
Ancient Tomb
32%inclusion49 decks154 decks
20%synergy
Opposition Agent
25%inclusion39 decks154 decks
16%synergy
Imperial Seal
24%inclusion37 decks154 decks
17%synergy
Chrome Mox
20%inclusion31 decks154 decks
14%synergy
Necropotence
19%inclusion30 decks154 decks
5%synergy
Creatures
Gray Merchant of Asphodel
59%inclusion91 decks154 decks
8%synergy
Enduring Tenacity
59%inclusion90 decks153 decks
51%synergy
Fate Unraveler
58%inclusion89 decks154 decks
55%synergy
Master of the Feast
57%inclusion88 decks154 decks
55%synergy
Bloodthirsty Conqueror
55%inclusion84 decks152 decks
46%synergy
Psychosis Crawler
49%inclusion75 decks154 decks
45%synergy
Bloodletter of Aclazotz
46%inclusion71 decks154 decks
36%synergy
Erebos, God of the Dead
45%inclusion70 decks154 decks
41%synergy
Vilis, Broker of Blood
44%inclusion68 decks154 decks
31%synergy
Witch of the Moors
37%inclusion57 decks154 decks
33%synergy
Rankle, Master of Pranks
34%inclusion53 decks154 decks
22%synergy
Phyrexian Obliterator
31%inclusion48 decks154 decks
20%synergy
Gixian Puppeteer
31%inclusion48 decks154 decks
27%synergy
Dread Presence
28%inclusion43 decks154 decks
14%synergy
Sheoldred, Whispering One
28%inclusion43 decks154 decks
16%synergy
Elder Brain
28%inclusion43 decks154 decks
25%synergy
Starscape Cleric
26%inclusion40 decks153 decks
23%synergy
Dauthi Voidwalker
26%inclusion40 decks154 decks
10%synergy
Bloodgift Demon
20%inclusion31 decks154 decks
17%synergy
Sheoldred
19%inclusion30 decks154 decks
13%synergy
Gix, Yawgmoth Praetor
16%inclusion25 decks154 decks
11%synergy
Solemn Simulacrum
14%inclusion22 decks154 decks
-8%synergy
Blood Artist
14%inclusion21 decks154 decks
-18%synergy
Massacre Wurm
14%inclusion21 decks154 decks
-3%synergy
Unstoppable Slasher
12%inclusion18 decks152 decks
6%synergy
Braids, Arisen Nightmare
11%inclusion17 decks154 decks
-8%synergy
Zenith Chronicler
10%inclusion16 decks154 decks
9%synergy
Ayara, First of Locthwain
9.1%inclusion14 decks154 decks
-17%synergy
Veinwitch Coven
9.1%inclusion14 decks154 decks
7%synergy
Creeping Bloodsucker
8.4%inclusion13 decks154 decks
4%synergy
Dark Confidant
8.4%inclusion13 decks154 decks
1%synergy
Roaming Throne
8.4%inclusion13 decks154 decks
5%synergy
Nirkana Revenant
8.4%inclusion13 decks154 decks
-3%synergy
Howling Golem
8.4%inclusion13 decks154 decks
7%synergy
Defiant Bloodlord
8.4%inclusion13 decks154 decks
7%synergy
Tergrid, God of Fright
8.4%inclusion13 decks154 decks
1%synergy
Skirge Familiar
8.4%inclusion13 decks154 decks
3%synergy
Epicure of Blood
8.4%inclusion13 decks154 decks
7%synergy
Bloodthirsty Aerialist
7.8%inclusion12 decks154 decks
6%synergy
Gwenom, Remorseless
6.5%inclusion7 decks107 decks
3%synergy
Boggart Trawler
6.5%inclusion10 decks154 decks
-2%synergy
Varragoth, Bloodsky Sire
6.5%inclusion10 decks154 decks
2%synergy
Archfiend of Despair
6.5%inclusion10 decks154 decks
4%synergy
Sanguine Syphoner
5.9%inclusion9 decks152 decks
5%synergy
Magus of the Coffers
5.8%inclusion9 decks154 decks
-1%synergy
Defiler of Flesh
5.8%inclusion9 decks154 decks
2%synergy
Mai, Scornful Striker
5.8%inclusion5 decks86 decks
4%synergy
Blood Seeker
5.2%inclusion8 decks154 decks
4%synergy
Indulgent Tormentor
5.2%inclusion8 decks154 decks
3%synergy
Instants
Deadly Rollick
51%inclusion78 decks154 decks
26%synergy
Baleful Mastery
49%inclusion76 decks154 decks
41%synergy
Imp's Mischief
42%inclusion64 decks154 decks
17%synergy
Malakir Rebirth
38%inclusion58 decks154 decks
15%synergy
Infernal Grasp
34%inclusion53 decks154 decks
9%synergy
Blood Pact
34%inclusion53 decks154 decks
30%synergy
Defile
34%inclusion52 decks154 decks
-3%synergy
Withering Torment
31%inclusion47 decks152 decks
-1%synergy
Sheoldred's Edict
25%inclusion38 decks154 decks
10%synergy
Feign Death
23%inclusion36 decks154 decks
15%synergy
Dismember
23%inclusion35 decks154 decks
12%synergy
Cabal Ritual
22%inclusion34 decks154 decks
4%synergy
Undying Malice
22%inclusion34 decks154 decks
12%synergy
Go for the Throat
21%inclusion32 decks154 decks
-2%synergy
Snuff Out
20%inclusion31 decks154 decks
7%synergy
Not Dead After All
18%inclusion28 decks154 decks
7%synergy
Necrologia
18%inclusion28 decks154 decks
17%synergy
Fell the Profane
18%inclusion27 decks154 decks
-1%synergy
Darkness
18%inclusion27 decks154 decks
8%synergy
Bitter Triumph
15%inclusion23 decks154 decks
5%synergy
Force of Despair
12%inclusion19 decks154 decks
5%synergy
Soul Shatter
12%inclusion19 decks154 decks
0%synergy
Consuming Corruption
10%inclusion16 decks154 decks
-5%synergy
Culling the Weak
10%inclusion16 decks154 decks
-6%synergy
Supernatural Stamina
10%inclusion16 decks154 decks
3%synergy
Withering Boon
10%inclusion16 decks154 decks
6%synergy
Ad Nauseam
10%inclusion16 decks154 decks
8%synergy
Murder
9.1%inclusion14 decks154 decks
-1%synergy
Hero's Downfall
7.8%inclusion12 decks154 decks
1%synergy
Deadly Dispute
7.8%inclusion12 decks154 decks
-18%synergy
Village Rites
7.1%inclusion11 decks154 decks
-18%synergy
Fake Your Own Death
7.1%inclusion11 decks154 decks
0%synergy
Sudden Spoiling
5.8%inclusion9 decks154 decks
-3%synergy
Stinging Study
5.2%inclusion8 decks154 decks
3%synergy
Undying Evil
5.2%inclusion8 decks154 decks
2%synergy
Doom Blade
5.2%inclusion8 decks154 decks
-2%synergy
Archenemy's Charm
5.2%inclusion6 decks116 decks
-4%synergy
Sorceries
Feed the Swarm
58%inclusion90 decks154 decks
8%synergy
Night's Whisper
53%inclusion81 decks154 decks
28%synergy
Damnation
49%inclusion75 decks154 decks
28%synergy
Reanimate
44%inclusion67 decks154 decks
4%synergy
Exsanguinate
40%inclusion62 decks154 decks
16%synergy
Insatiable Avarice
40%inclusion61 decks154 decks
28%synergy
Grim Tutor
39%inclusion60 decks154 decks
27%synergy
Read the Bones
30%inclusion46 decks154 decks
13%synergy
Torment of Hailfire
26%inclusion40 decks154 decks
11%synergy
Diabolic Tutor
19%inclusion30 decks154 decks
5%synergy
Mutilate
19%inclusion30 decks154 decks
2%synergy
Bubbling Muck
19%inclusion29 decks154 decks
3%synergy
Eldritch Pact
14%inclusion22 decks154 decks
13%synergy
Syphon Mind
12%inclusion19 decks154 decks
0%synergy
Beseech the Mirror
11%inclusion17 decks154 decks
4%synergy
Blasphemous Edict
11%inclusion16 decks152 decks
-6%synergy
Profane Tutor
10%inclusion16 decks154 decks
6%synergy
Thoughtseize
10%inclusion16 decks154 decks
6%synergy
Diabolic Intent
10%inclusion15 decks154 decks
-5%synergy
Painful Lesson
9.1%inclusion14 decks154 decks
8%synergy
Ambition's Cost
9.1%inclusion14 decks154 decks
6%synergy
Pain's Reward
7.8%inclusion12 decks154 decks
7%synergy
Praetor's Grasp
7.8%inclusion12 decks154 decks
4%synergy
Rise of the Dark Realms
7.8%inclusion12 decks154 decks
-5%synergy
Atrocious Experiment
7.1%inclusion11 decks154 decks
6%synergy
Temporal Extortion
6.5%inclusion10 decks154 decks
4%synergy
Dark Petition
6.5%inclusion10 decks154 decks
3%synergy
Black Sun's Zenith
5.8%inclusion9 decks154 decks
0%synergy
Yawgmoth's Will
5.8%inclusion9 decks154 decks
2%synergy
Ancient Craving
5.8%inclusion9 decks154 decks
4%synergy
Decree of Pain
5.8%inclusion9 decks154 decks
0%synergy
Pact of the Serpent
5.8%inclusion9 decks154 decks
4%synergy
Scheming Symmetry
5.2%inclusion8 decks154 decks
1%synergy
Utility Artifacts
Font of Mythos
56%inclusion87 decks154 decks
54%synergy
Alhammarret's Archive
53%inclusion81 decks154 decks
49%synergy
Temple Bell
48%inclusion74 decks154 decks
46%synergy
Swiftfoot Boots
45%inclusion70 decks154 decks
14%synergy
Aetherflux Reservoir
42%inclusion64 decks154 decks
32%synergy
Sensei's Divining Top
35%inclusion54 decks154 decks
27%synergy
Horn of Greed
29%inclusion44 decks154 decks
27%synergy
Mindcrank
24%inclusion37 decks154 decks
19%synergy
Mithril Coat
22%inclusion34 decks154 decks
17%synergy
Commander's Plate
20%inclusion31 decks154 decks
14%synergy
Well of Lost Dreams
18%inclusion27 decks154 decks
16%synergy
The Darkness Crystal
16%inclusion20 decks128 decks
-4%synergy
Bontu's Monument
14%inclusion22 decks154 decks
-14%synergy
Venser's Journal
14%inclusion22 decks154 decks
13%synergy
Expedition Map
12%inclusion19 decks154 decks
1%synergy
Memory Jar
12%inclusion19 decks154 decks
11%synergy
Wishclaw Talisman
10%inclusion15 decks154 decks
3%synergy
Anvil of Bogardan
10%inclusion15 decks154 decks
8%synergy
Spellbook
6.5%inclusion10 decks154 decks
6%synergy
Otherworld Atlas
6.5%inclusion10 decks154 decks
6%synergy
Wayfarer's Bauble
5.8%inclusion9 decks154 decks
-9%synergy
Requiem Monolith
5.3%inclusion6 decks114 decks
4%synergy
Enchantments
Black Market Connections
47%inclusion72 decks154 decks
23%synergy
Bloodchief Ascension
41%inclusion63 decks154 decks
32%synergy
Greed
32%inclusion49 decks154 decks
25%synergy
No Mercy
29%inclusion44 decks154 decks
21%synergy
Necrodominance
25%inclusion39 decks154 decks
23%synergy
Kaya's Ghostform
24%inclusion37 decks154 decks
14%synergy
The Meathook Massacre
21%inclusion33 decks154 decks
4%synergy
Lich's Mastery
18%inclusion27 decks154 decks
16%synergy
Wound Reflection
14%inclusion22 decks154 decks
11%synergy
Painful Quandary
14%inclusion22 decks154 decks
4%synergy
Phyrexian Reclamation
12%inclusion18 decks154 decks
2%synergy
Animate Dead
12%inclusion18 decks154 decks
-6%synergy
Bitterblossom
12%inclusion18 decks154 decks
-1%synergy
Polluted Bonds
7.1%inclusion11 decks154 decks
5%synergy
Oubliette
7.1%inclusion11 decks154 decks
4%synergy
Black Market
6.5%inclusion10 decks154 decks
-15%synergy
Contamination
5.2%inclusion8 decks154 decks
2%synergy
Planeswalkers
Ob Nixilis, the Hate-Twisted
38%inclusion58 decks154 decks
35%synergy
Ob Nixilis Reignited
20%inclusion31 decks154 decks
18%synergy
Liliana of the Dark Realms
15%inclusion23 decks154 decks
1%synergy
Utility Lands
Cabal Coffers
81%inclusion124 decks154 decks
26%synergy
Reliquary Tower
76%inclusion117 decks154 decks
46%synergy
Geier Reach Sanitarium
57%inclusion88 decks154 decks
46%synergy
Urborg, Tomb of Yawgmoth
55%inclusion85 decks154 decks
18%synergy
Cabal Stronghold
53%inclusion81 decks154 decks
18%synergy
Bojuka Bog
52%inclusion80 decks154 decks
5%synergy
Mikokoro, Center of the Sea
51%inclusion79 decks154 decks
49%synergy
Nykthos, Shrine to Nyx
44%inclusion67 decks154 decks
14%synergy
Command Beacon
27%inclusion41 decks154 decks
18%synergy
Urza's Saga
19%inclusion30 decks154 decks
12%synergy
War Room
19%inclusion30 decks154 decks
3%synergy
Takenuma, Abandoned Mire
19%inclusion30 decks154 decks
4%synergy
Witch's Cottage
17%inclusion26 decks154 decks
-8%synergy
Castle Locthwain
17%inclusion26 decks154 decks
0%synergy
Phyrexian Tower
16%inclusion25 decks154 decks
-9%synergy
Lake of the Dead
13%inclusion20 decks154 decks
8%synergy
Mortuary Mire
12%inclusion18 decks154 decks
-1%synergy
Maze of Ith
10%inclusion15 decks154 decks
7%synergy
Shizo, Death's Storehouse
9.1%inclusion14 decks154 decks
-1%synergy
Deserted Temple
9.1%inclusion14 decks154 decks
5%synergy
Strip Mine
9.1%inclusion14 decks154 decks
6%synergy
Thespian's Stage
8.4%inclusion13 decks154 decks
3%synergy
The Dross Pits
6.5%inclusion10 decks154 decks
5%synergy
Barren Moor
5.8%inclusion9 decks154 decks
-4%synergy
Vesuva
5.8%inclusion9 decks154 decks
3%synergy
Glacial Chasm
5.8%inclusion9 decks154 decks
5%synergy
Temple of the False God
5.8%inclusion9 decks154 decks
-2%synergy
Wasteland
5.2%inclusion8 decks154 decks
4%synergy
Volrath's Stronghold
5.2%inclusion8 decks154 decks
1%synergy
Mana Artifacts
Sol Ring
96%inclusion148 decks154 decks
10%synergy
Thought Vessel
75%inclusion115 decks154 decks
49%synergy
Arcane Signet
67%inclusion103 decks154 decks
5%synergy
Mind Stone
35%inclusion54 decks154 decks
6%synergy
Decanter of Endless Water
20%inclusion31 decks154 decks
17%synergy
Lotus Petal
18%inclusion28 decks154 decks
11%synergy
Throne of Eldraine
18%inclusion28 decks154 decks
8%synergy
The Soul Stone
15%inclusion16 decks108 decks
0%synergy
Mana Vault
14%inclusion22 decks154 decks
8%synergy
Charcoal Diamond
13%inclusion20 decks154 decks
-9%synergy
Fellwar Stone
10%inclusion16 decks154 decks
-4%synergy
Commander's Sphere
9.1%inclusion14 decks154 decks
1%synergy
Sceptre of Eternal Glory
9.1%inclusion14 decks154 decks
1%synergy
Mox Diamond
8.4%inclusion13 decks154 decks
5%synergy
Nyx Lotus
7.8%inclusion12 decks154 decks
2%synergy
Mox Amber
7.1%inclusion11 decks154 decks
3%synergy
Extraplanar Lens
6.5%inclusion10 decks154 decks
2%synergy
Mox Opal
5.8%inclusion9 decks154 decks
2%synergy
Lands
Swamp
94%inclusion145 decks154 decks
-1%synergy
Malakir Rebirth
38%inclusion58 decks154 decks
15%synergy
Fell the Profane
18%inclusion27 decks154 decks
-1%synergy
Myriad Landscape
16%inclusion25 decks154 decks
-9%synergy
Urza's Cave
10%inclusion16 decks154 decks
2%synergy
Cavern of Souls
10%inclusion16 decks154 decks
4%synergy
Snow-Covered Swamp
9.1%inclusion14 decks154 decks
3%synergy
Command Tower
6.5%inclusion10 decks154 decks
1%synergy
Boggart Trawler
6.5%inclusion10 decks154 decks
-2%synergy
Gemstone Caverns
5.8%inclusion9 decks154 decks
1%synergy
Polluted Delta
5.8%inclusion9 decks154 decks
2%synergy
Demolition Field
5.2%inclusion8 decks154 decks
0%synergy
Plaza of Heroes
5.2%inclusion8 decks154 decks
4%synergy
Bloodstained Mire
5.2%inclusion8 decks154 decks
2%synergy
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