Sheoldred, the Apocalypse (Commander) - Optimized Lifegain

Sheoldred, the Apocalypse
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Zoe Ley
Apr 14, 2026
Zoe Ley
The 10 Best Prepared Cards in Secrets of Strixhaven
The new prepared mechanic from Secrets of Strixhaven looks like it'll have some very strong cards for Commander. But which ones are the best?
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Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
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Decorum Dissertation
31%inclusion16 decks51 decks
26%synergy
Scheming Silvertongue
30%inclusion15 decks50 decks
23%synergy
Pox Plague
8.0%inclusion4 decks50 decks
3%synergy
Withering Curse
7.0%inclusion4 decks57 decks
5%synergy
Emeritus of Woe
4.0%inclusion2 decks50 decks
-4%synergy
High Synergy Cards
Underworld Dreams
82%inclusion133 decks163 decks
76%synergy
Peer into the Abyss
85%inclusion139 decks163 decks
75%synergy
Teferi's Puzzle Box
75%inclusion123 decks163 decks
73%synergy
Howling Mine
72%inclusion118 decks163 decks
68%synergy
Vito, Thorn of the Dusk Rose
76%inclusion124 decks163 decks
65%synergy
Seizan, Perverter of Truth
65%inclusion106 decks163 decks
61%synergy
Dark Deal
70%inclusion114 decks163 decks
59%synergy
Exquisite Blood
71%inclusion116 decks163 decks
58%synergy
Marauding Blight-Priest
64%inclusion105 decks163 decks
57%synergy
Fate Unraveler
60%inclusion98 decks163 decks
57%synergy
Top Cards
Dark Ritual
90%inclusion147 decks163 decks
23%synergy
Jet Medallion
81%inclusion132 decks163 decks
19%synergy
Phyrexian Arena
77%inclusion126 decks163 decks
38%synergy
Sign in Blood
74%inclusion120 decks163 decks
38%synergy
Crypt Ghast
71%inclusion116 decks163 decks
24%synergy
Sanguine Bond
65%inclusion106 decks163 decks
53%synergy
Lightning Greaves
64%inclusion105 decks163 decks
31%synergy
Toxic Deluge
61%inclusion100 decks163 decks
25%synergy
Scrawling Crawler
60%inclusion97 decks161 decks
56%synergy
Gray Merchant of Asphodel
60%inclusion97 decks163 decks
9%synergy
Game Changers
Demonic Tutor
67%inclusion109 decks163 decks
40%synergy
Bolas's Citadel
66%inclusion108 decks163 decks
38%synergy
Orcish Bowmasters
64%inclusion104 decks163 decks
51%synergy
Vampiric Tutor
56%inclusion91 decks163 decks
35%synergy
The One Ring
48%inclusion78 decks163 decks
39%synergy
Ancient Tomb
31%inclusion51 decks163 decks
20%synergy
Opposition Agent
25%inclusion41 decks163 decks
16%synergy
Imperial Seal
23%inclusion38 decks163 decks
16%synergy
Necropotence
20%inclusion33 decks163 decks
6%synergy
Chrome Mox
18%inclusion30 decks163 decks
12%synergy
Creatures
K'rrik, Son of Yawgmoth
58%inclusion94 decks163 decks
38%synergy
Enduring Tenacity
57%inclusion93 decks162 decks
50%synergy
Bloodthirsty Conqueror
55%inclusion89 decks161 decks
46%synergy
Master of the Feast
55%inclusion89 decks163 decks
52%synergy
Psychosis Crawler
50%inclusion82 decks163 decks
47%synergy
Bloodletter of Aclazotz
45%inclusion73 decks163 decks
34%synergy
Vilis, Broker of Blood
45%inclusion73 decks163 decks
32%synergy
Erebos, God of the Dead
44%inclusion72 decks163 decks
40%synergy
Witch of the Moors
37%inclusion60 decks163 decks
33%synergy
Rankle, Master of Pranks
36%inclusion58 decks163 decks
23%synergy
Gixian Puppeteer
30%inclusion49 decks163 decks
26%synergy
Dread Presence
29%inclusion47 decks163 decks
15%synergy
Phyrexian Obliterator
28%inclusion46 decks163 decks
17%synergy
Sheoldred, Whispering One
28%inclusion46 decks163 decks
17%synergy
Elder Brain
28%inclusion45 decks163 decks
25%synergy
Dauthi Voidwalker
28%inclusion45 decks163 decks
12%synergy
Starscape Cleric
27%inclusion44 decks162 decks
24%synergy
Bloodgift Demon
21%inclusion34 decks163 decks
18%synergy
Sheoldred
17%inclusion28 decks163 decks
11%synergy
Solemn Simulacrum
15%inclusion25 decks163 decks
-6%synergy
Gix, Yawgmoth Praetor
15%inclusion25 decks163 decks
10%synergy
Blood Artist
13%inclusion22 decks163 decks
-18%synergy
Massacre Wurm
13%inclusion22 decks163 decks
-4%synergy
Braids, Arisen Nightmare
12%inclusion20 decks163 decks
-7%synergy
Unstoppable Slasher
12%inclusion19 decks161 decks
6%synergy
Zenith Chronicler
11%inclusion18 decks163 decks
10%synergy
Roaming Throne
10%inclusion16 decks163 decks
7%synergy
Ayara, First of Locthwain
10%inclusion16 decks163 decks
-16%synergy
Veinwitch Coven
10%inclusion16 decks163 decks
8%synergy
Howling Golem
9.2%inclusion15 decks163 decks
8%synergy
Defiant Bloodlord
9.2%inclusion15 decks163 decks
7%synergy
Epicure of Blood
9.2%inclusion15 decks163 decks
8%synergy
Creeping Bloodsucker
8.6%inclusion14 decks163 decks
4%synergy
Tergrid, God of Fright
8.6%inclusion14 decks163 decks
1%synergy
Skirge Familiar
8.6%inclusion14 decks163 decks
4%synergy
Dark Confidant
8.0%inclusion13 decks163 decks
0%synergy
Nirkana Revenant
8.0%inclusion13 decks163 decks
-3%synergy
Gwenom, Remorseless
7.8%inclusion9 decks116 decks
4%synergy
Archfiend of Despair
7.4%inclusion12 decks163 decks
5%synergy
Bloodthirsty Aerialist
7.4%inclusion12 decks163 decks
6%synergy
Varragoth, Bloodsky Sire
6.7%inclusion11 decks163 decks
2%synergy
Boggart Trawler
6.1%inclusion10 decks163 decks
-3%synergy
Sanguine Syphoner
5.6%inclusion9 decks161 decks
5%synergy
Magus of the Coffers
5.5%inclusion9 decks163 decks
-1%synergy
Instants
Deadly Rollick
52%inclusion85 decks163 decks
28%synergy
Baleful Mastery
49%inclusion80 decks163 decks
41%synergy
Imp's Mischief
42%inclusion68 decks163 decks
17%synergy
Malakir Rebirth
37%inclusion61 decks163 decks
14%synergy
Infernal Grasp
36%inclusion59 decks163 decks
11%synergy
Defile
35%inclusion57 decks163 decks
-1%synergy
Blood Pact
34%inclusion56 decks163 decks
30%synergy
Withering Torment
32%inclusion52 decks161 decks
1%synergy
Sheoldred's Edict
26%inclusion43 decks163 decks
12%synergy
Feign Death
23%inclusion38 decks163 decks
15%synergy
Go for the Throat
22%inclusion36 decks163 decks
-1%synergy
Cabal Ritual
22%inclusion36 decks163 decks
4%synergy
Dismember
22%inclusion36 decks163 decks
12%synergy
Undying Malice
21%inclusion34 decks163 decks
11%synergy
Snuff Out
20%inclusion32 decks163 decks
6%synergy
Not Dead After All
19%inclusion31 decks163 decks
8%synergy
Darkness
18%inclusion29 decks163 decks
8%synergy
Bitter Triumph
17%inclusion27 decks163 decks
7%synergy
Necrologia
17%inclusion27 decks163 decks
15%synergy
Fell the Profane
16%inclusion26 decks163 decks
-3%synergy
Force of Despair
12%inclusion20 decks163 decks
5%synergy
Soul Shatter
12%inclusion19 decks163 decks
0%synergy
Withering Boon
11%inclusion18 decks163 decks
7%synergy
Supernatural Stamina
10%inclusion17 decks163 decks
3%synergy
Murder
10%inclusion17 decks163 decks
0%synergy
Ad Nauseam
10%inclusion17 decks163 decks
8%synergy
Consuming Corruption
10%inclusion16 decks163 decks
-6%synergy
Culling the Weak
10%inclusion16 decks163 decks
-7%synergy
Hero's Downfall
8.6%inclusion14 decks163 decks
2%synergy
Deadly Dispute
8.6%inclusion14 decks163 decks
-18%synergy
Sudden Spoiling
8.6%inclusion14 decks163 decks
0%synergy
Village Rites
8.0%inclusion13 decks163 decks
-18%synergy
Archenemy's Charm
7.2%inclusion9 decks125 decks
-2%synergy
Fake Your Own Death
6.7%inclusion11 decks163 decks
-1%synergy
Stinging Study
6.1%inclusion10 decks163 decks
4%synergy
Sorceries
Feed the Swarm
59%inclusion96 decks163 decks
9%synergy
Damnable Pact
56%inclusion92 decks163 decks
52%synergy
Night's Whisper
53%inclusion87 decks163 decks
29%synergy
Damnation
48%inclusion78 decks163 decks
28%synergy
Reanimate
43%inclusion70 decks163 decks
3%synergy
Exsanguinate
39%inclusion64 decks163 decks
15%synergy
Insatiable Avarice
39%inclusion63 decks163 decks
27%synergy
Grim Tutor
36%inclusion58 decks163 decks
24%synergy
Read the Bones
33%inclusion53 decks163 decks
16%synergy
Torment of Hailfire
26%inclusion42 decks163 decks
10%synergy
Diabolic Tutor
22%inclusion36 decks163 decks
8%synergy
Mutilate
20%inclusion33 decks163 decks
4%synergy
Bubbling Muck
19%inclusion31 decks163 decks
3%synergy
Eldritch Pact
15%inclusion25 decks163 decks
14%synergy
Syphon Mind
12%inclusion20 decks163 decks
0%synergy
Blasphemous Edict
11%inclusion17 decks161 decks
-6%synergy
Painful Lesson
10%inclusion17 decks163 decks
9%synergy
Beseech the Mirror
10%inclusion17 decks163 decks
4%synergy
Diabolic Intent
10%inclusion16 decks163 decks
-5%synergy
Profane Tutor
9.2%inclusion15 decks163 decks
5%synergy
Ambition's Cost
9.2%inclusion15 decks163 decks
6%synergy
Rise of the Dark Realms
9.2%inclusion15 decks163 decks
-4%synergy
Thoughtseize
9.2%inclusion15 decks163 decks
5%synergy
Praetor's Grasp
8.0%inclusion13 decks163 decks
4%synergy
Pain's Reward
7.4%inclusion12 decks163 decks
7%synergy
Atrocious Experiment
6.7%inclusion11 decks163 decks
6%synergy
Temporal Extortion
6.1%inclusion10 decks163 decks
4%synergy
Dark Petition
6.1%inclusion10 decks163 decks
2%synergy
Black Sun's Zenith
5.5%inclusion9 decks163 decks
0%synergy
Scheming Symmetry
5.5%inclusion9 decks163 decks
1%synergy
Utility Artifacts
Font of Mythos
53%inclusion87 decks163 decks
51%synergy
Alhammarret's Archive
50%inclusion81 decks163 decks
46%synergy
Swiftfoot Boots
47%inclusion76 decks163 decks
15%synergy
Temple Bell
44%inclusion71 decks163 decks
41%synergy
Aetherflux Reservoir
41%inclusion67 decks163 decks
32%synergy
Sensei's Divining Top
34%inclusion56 decks163 decks
26%synergy
Horn of Greed
26%inclusion43 decks163 decks
25%synergy
Mindcrank
23%inclusion37 decks163 decks
17%synergy
Mithril Coat
22%inclusion36 decks163 decks
17%synergy
Commander's Plate
20%inclusion33 decks163 decks
14%synergy
Well of Lost Dreams
18%inclusion30 decks163 decks
17%synergy
The Darkness Crystal
16%inclusion22 decks137 decks
-4%synergy
Bontu's Monument
13%inclusion22 decks163 decks
-15%synergy
Expedition Map
13%inclusion21 decks163 decks
1%synergy
Venser's Journal
13%inclusion21 decks163 decks
11%synergy
Memory Jar
12%inclusion19 decks163 decks
11%synergy
Wishclaw Talisman
10%inclusion17 decks163 decks
4%synergy
Anvil of Bogardan
8.6%inclusion14 decks163 decks
7%synergy
Wayfarer's Bauble
6.1%inclusion10 decks163 decks
-9%synergy
Spellbook
6.1%inclusion10 decks163 decks
5%synergy
Otherworld Atlas
6.1%inclusion10 decks163 decks
5%synergy
Enchantments
Black Market Connections
44%inclusion72 decks163 decks
20%synergy
Bloodchief Ascension
40%inclusion66 decks163 decks
31%synergy
Greed
33%inclusion54 decks163 decks
27%synergy
No Mercy
28%inclusion45 decks163 decks
20%synergy
Kaya's Ghostform
25%inclusion40 decks163 decks
15%synergy
Necrodominance
24%inclusion39 decks163 decks
21%synergy
The Meathook Massacre
21%inclusion34 decks163 decks
3%synergy
Lich's Mastery
19%inclusion31 decks163 decks
18%synergy
Painful Quandary
15%inclusion25 decks163 decks
5%synergy
Wound Reflection
14%inclusion23 decks163 decks
11%synergy
Animate Dead
13%inclusion22 decks163 decks
-4%synergy
Phyrexian Reclamation
11%inclusion18 decks163 decks
1%synergy
Bitterblossom
10%inclusion17 decks163 decks
-3%synergy
Oubliette
7.4%inclusion12 decks163 decks
4%synergy
Polluted Bonds
6.7%inclusion11 decks163 decks
5%synergy
Black Market
6.1%inclusion10 decks163 decks
-15%synergy
Grave Pact
5.5%inclusion9 decks163 decks
-14%synergy
Planeswalkers
Ob Nixilis, the Hate-Twisted
38%inclusion62 decks163 decks
36%synergy
Ob Nixilis Reignited
21%inclusion35 decks163 decks
19%synergy
Liliana of the Dark Realms
17%inclusion27 decks163 decks
3%synergy
Utility Lands
Cabal Coffers
80%inclusion131 decks163 decks
26%synergy
Reliquary Tower
75%inclusion122 decks163 decks
45%synergy
Geier Reach Sanitarium
58%inclusion95 decks163 decks
48%synergy
Urborg, Tomb of Yawgmoth
54%inclusion88 decks163 decks
16%synergy
Bojuka Bog
52%inclusion85 decks163 decks
5%synergy
Cabal Stronghold
52%inclusion84 decks163 decks
17%synergy
Mikokoro, Center of the Sea
48%inclusion78 decks163 decks
45%synergy
Nykthos, Shrine to Nyx
43%inclusion70 decks163 decks
13%synergy
Command Beacon
26%inclusion43 decks163 decks
18%synergy
Witch's Cottage
21%inclusion34 decks163 decks
-4%synergy
War Room
19%inclusion31 decks163 decks
3%synergy
Takenuma, Abandoned Mire
19%inclusion31 decks163 decks
3%synergy
Urza's Saga
18%inclusion30 decks163 decks
10%synergy
Phyrexian Tower
16%inclusion26 decks163 decks
-10%synergy
Castle Locthwain
16%inclusion26 decks163 decks
-1%synergy
Mortuary Mire
13%inclusion21 decks163 decks
0%synergy
Lake of the Dead
12%inclusion20 decks163 decks
7%synergy
Deserted Temple
10%inclusion16 decks163 decks
6%synergy
Shizo, Death's Storehouse
9.2%inclusion15 decks163 decks
-1%synergy
Thespian's Stage
9.2%inclusion15 decks163 decks
4%synergy
Maze of Ith
8.0%inclusion13 decks163 decks
5%synergy
Strip Mine
8.0%inclusion13 decks163 decks
5%synergy
Temple of the False God
7.4%inclusion12 decks163 decks
0%synergy
Barren Moor
6.1%inclusion10 decks163 decks
-3%synergy
Vesuva
6.1%inclusion10 decks163 decks
3%synergy
Volrath's Stronghold
6.1%inclusion10 decks163 decks
2%synergy
The Dross Pits
6.1%inclusion10 decks163 decks
5%synergy
Glacial Chasm
5.5%inclusion9 decks163 decks
5%synergy
Mana Artifacts
Sol Ring
96%inclusion156 decks163 decks
10%synergy
Thought Vessel
72%inclusion117 decks163 decks
47%synergy
Arcane Signet
67%inclusion109 decks163 decks
5%synergy
Mind Stone
37%inclusion60 decks163 decks
8%synergy
Decanter of Endless Water
20%inclusion33 decks163 decks
17%synergy
Lotus Petal
18%inclusion30 decks163 decks
11%synergy
Throne of Eldraine
18%inclusion29 decks163 decks
8%synergy
The Soul Stone
16%inclusion19 decks117 decks
1%synergy
Charcoal Diamond
16%inclusion26 decks163 decks
-6%synergy
Mana Vault
15%inclusion25 decks163 decks
9%synergy
Commander's Sphere
10%inclusion17 decks163 decks
2%synergy
Fellwar Stone
10%inclusion17 decks163 decks
-4%synergy
Sceptre of Eternal Glory
9.2%inclusion15 decks163 decks
1%synergy
Mox Diamond
8.0%inclusion13 decks163 decks
4%synergy
Mox Amber
7.4%inclusion12 decks163 decks
3%synergy
Nyx Lotus
7.4%inclusion12 decks163 decks
1%synergy
Mox Opal
5.5%inclusion9 decks163 decks
2%synergy
Extraplanar Lens
5.5%inclusion9 decks163 decks
1%synergy
Lands
Swamp
95%inclusion155 decks163 decks
0%synergy
Malakir Rebirth
37%inclusion61 decks163 decks
14%synergy
Fell the Profane
16%inclusion26 decks163 decks
-3%synergy
Myriad Landscape
15%inclusion25 decks163 decks
-10%synergy
Urza's Cave
12%inclusion19 decks163 decks
3%synergy
Cavern of Souls
10%inclusion17 decks163 decks
4%synergy
Snow-Covered Swamp
8.0%inclusion13 decks163 decks
1%synergy
Command Tower
7.4%inclusion12 decks163 decks
2%synergy
Boggart Trawler
6.1%inclusion10 decks163 decks
-3%synergy
Gemstone Caverns
6.1%inclusion10 decks163 decks
2%synergy
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