Skithiryx, the Blight Dragon (Commander) - Upgraded Proliferate

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #813
4decks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Enchantments
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Utility Lands
Mana Artifacts
Lands
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My Precious
33%inclusion1 decks3 decks
31%synergy
The Sackville-Bagginses
33%inclusion1 decks3 decks
32%synergy
High Synergy Cards
Phyresis Outbreak
100%inclusion4 decks4 decks
98%synergy
Contagion Engine
100%inclusion4 decks4 decks
98%synergy
Contagion Clasp
100%inclusion4 decks4 decks
98%synergy
Infectious Inquiry
100%inclusion4 decks4 decks
97%synergy
Ichor Rats
100%inclusion4 decks4 decks
97%synergy
Blightbelly Rat
100%inclusion4 decks4 decks
97%synergy
Karn's Bastion
100%inclusion4 decks4 decks
96%synergy
Urborg, Tomb of Yawgmoth
100%inclusion4 decks4 decks
62%synergy
Cabal Coffers
100%inclusion4 decks4 decks
45%synergy
Dark Ritual
100%inclusion4 decks4 decks
33%synergy
Game Changers
Demonic Tutor
50%inclusion2 decks4 decks
23%synergy
Vampiric Tutor
50%inclusion2 decks4 decks
29%synergy
Imperial Seal
25%inclusion1 decks4 decks
18%synergy
Opposition Agent
25%inclusion1 decks4 decks
16%synergy
Ancient Tomb
25%inclusion1 decks4 decks
13%synergy
The One Ring
25%inclusion1 decks4 decks
16%synergy
Mana Vault
25%inclusion1 decks4 decks
18%synergy
Orcish Bowmasters
25%inclusion1 decks4 decks
12%synergy
Creatures
Plague Stinger
75%inclusion3 decks4 decks
74%synergy
Whispering Specter
75%inclusion3 decks4 decks
74%synergy
Reaper of Sheoldred
75%inclusion3 decks4 decks
74%synergy
Plague Myr
75%inclusion3 decks4 decks
74%synergy
Phyrexian Crusader
75%inclusion3 decks4 decks
74%synergy
Yawgmoth, Thran Physician
75%inclusion3 decks4 decks
65%synergy
Crypt Ghast
75%inclusion3 decks4 decks
28%synergy
Hand of the Praetors
75%inclusion3 decks4 decks
74%synergy
Flensermite
50%inclusion2 decks4 decks
50%synergy
Flesh-Eater Imp
50%inclusion2 decks4 decks
49%synergy
Gulping Scraptrap
50%inclusion2 decks4 decks
50%synergy
Blightsteel Colossus
50%inclusion2 decks4 decks
49%synergy
Contagious Nim
25%inclusion1 decks4 decks
25%synergy
Gravecrawler
25%inclusion1 decks4 decks
10%synergy
Core Prowler
25%inclusion1 decks4 decks
24%synergy
Brainstealer Dragon
25%inclusion1 decks4 decks
22%synergy
Blackcleave Goblin
25%inclusion1 decks4 decks
25%synergy
Vector Asp
25%inclusion1 decks4 decks
25%synergy
Spitting Dilophosaurus
25%inclusion1 decks4 decks
24%synergy
Scrawling Crawler
25%inclusion1 decks4 decks
21%synergy
Vogar, Necropolis Tyrant
25%inclusion1 decks4 decks
24%synergy
Sedgemoor Witch
25%inclusion1 decks4 decks
23%synergy
Sheoldred, the Apocalypse
25%inclusion1 decks4 decks
10%synergy
Ayara, First of Locthwain
25%inclusion1 decks4 decks
0%synergy
Gray Merchant of Asphodel
25%inclusion1 decks4 decks
-25%synergy
Filth
25%inclusion1 decks4 decks
23%synergy
Phyrexian Obliterator
25%inclusion1 decks4 decks
14%synergy
Mikaeus, the Unhallowed
25%inclusion1 decks4 decks
18%synergy
Grafted Butcher
25%inclusion1 decks4 decks
25%synergy
Bilious Skulldweller
25%inclusion1 decks4 decks
24%synergy
Ichorclaw Myr
25%inclusion1 decks4 decks
25%synergy
Corpse Cur
25%inclusion1 decks4 decks
25%synergy
Sheoldred, Whispering One
25%inclusion1 decks4 decks
14%synergy
Death Baron
25%inclusion1 decks4 decks
20%synergy
Phyrexian Digester
25%inclusion1 decks4 decks
25%synergy
Carrion Feeder
25%inclusion1 decks4 decks
13%synergy
Pitiless Plunderer
25%inclusion1 decks4 decks
5%synergy
Warren Soultrader
25%inclusion1 decks4 decks
11%synergy
Black Dragon
25%inclusion1 decks4 decks
25%synergy
Toxic Nim
25%inclusion1 decks4 decks
25%synergy
Septic Rats
25%inclusion1 decks4 decks
23%synergy
K'rrik, Son of Yawgmoth
25%inclusion1 decks4 decks
6%synergy
Scheming Aspirant
25%inclusion1 decks4 decks
25%synergy
Necropede
25%inclusion1 decks4 decks
25%synergy
Vein Ripper
25%inclusion1 decks4 decks
21%synergy
Sephiroth, Fabled SOLDIER
25%inclusion1 decks4 decks
20%synergy
Surge Conductor
25%inclusion1 decks4 decks
25%synergy
Bitterbloom Bearer
25%inclusion1 decks4 decks
18%synergy
Dimension X Pizzasaur
25%inclusion1 decks4 decks
25%synergy
Big Mother Mouser
25%inclusion1 decks4 decks
25%synergy
Instants
Whisper of the Dross
75%inclusion3 decks4 decks
72%synergy
Vraska's Fall
75%inclusion3 decks4 decks
72%synergy
Astarion's Thirst
50%inclusion2 decks4 decks
49%synergy
Deadly Rollick
50%inclusion2 decks4 decks
24%synergy
Grim Affliction
50%inclusion2 decks4 decks
48%synergy
Defile
50%inclusion2 decks4 decks
15%synergy
Withering Boon
50%inclusion2 decks4 decks
46%synergy
Darkness
50%inclusion2 decks4 decks
39%synergy
Tainted Strike
50%inclusion2 decks4 decks
47%synergy
Sudden Spoiling
50%inclusion2 decks4 decks
42%synergy
Fell the Profane
25%inclusion1 decks4 decks
5%synergy
Stinging Study
25%inclusion1 decks4 decks
23%synergy
Go for the Throat
25%inclusion1 decks4 decks
3%synergy
Snuff Out
25%inclusion1 decks4 decks
11%synergy
Consuming Corruption
25%inclusion1 decks4 decks
10%synergy
Anoint with Affliction
25%inclusion1 decks4 decks
24%synergy
Howl from Beyond
25%inclusion1 decks4 decks
24%synergy
Hatred
25%inclusion1 decks4 decks
24%synergy
Doom Blade
25%inclusion1 decks4 decks
18%synergy
Cabal Ritual
25%inclusion1 decks4 decks
6%synergy
Culling the Weak
25%inclusion1 decks4 decks
7%synergy
Armor of Shadows
25%inclusion1 decks4 decks
23%synergy
Rush of Vitality
25%inclusion1 decks4 decks
24%synergy
Carrion
25%inclusion1 decks4 decks
25%synergy
Undying Malice
25%inclusion1 decks4 decks
15%synergy
Malakir Rebirth
25%inclusion1 decks4 decks
1%synergy
Rain of Filth
25%inclusion1 decks4 decks
22%synergy
Fake Your Own Death
25%inclusion1 decks4 decks
17%synergy
Offer Immortality
25%inclusion1 decks4 decks
23%synergy
Victim of Night
25%inclusion1 decks4 decks
23%synergy
Withering Torment
25%inclusion1 decks4 decks
-7%synergy
Overkill
25%inclusion1 decks4 decks
19%synergy
Archenemy's Charm
25%inclusion1 decks4 decks
16%synergy
Sorceries
Crux of Fate
75%inclusion3 decks4 decks
74%synergy
Feed the Swarm
75%inclusion3 decks4 decks
25%synergy
Drown in Ichor
75%inclusion3 decks4 decks
71%synergy
Vat Emergence
50%inclusion2 decks4 decks
49%synergy
Caress of Phyrexia
50%inclusion2 decks4 decks
49%synergy
Reanimate
50%inclusion2 decks4 decks
9%synergy
Toxic Deluge
50%inclusion2 decks4 decks
13%synergy
Damnation
50%inclusion2 decks4 decks
30%synergy
Spread the Sickness
25%inclusion1 decks4 decks
24%synergy
Diabolic Tutor
25%inclusion1 decks4 decks
11%synergy
Bubbling Muck
25%inclusion1 decks4 decks
9%synergy
Feed the Infection
25%inclusion1 decks4 decks
24%synergy
Agadeem's Awakening
25%inclusion1 decks4 decks
17%synergy
Mutilate
25%inclusion1 decks4 decks
10%synergy
Night's Whisper
25%inclusion1 decks4 decks
-0%synergy
Exsanguinate
25%inclusion1 decks4 decks
0%synergy
Buried Alive
25%inclusion1 decks4 decks
12%synergy
Ambition's Cost
25%inclusion1 decks4 decks
22%synergy
Syphon Mind
25%inclusion1 decks4 decks
13%synergy
Insatiable Avarice
25%inclusion1 decks4 decks
14%synergy
Bontu's Last Reckoning
25%inclusion1 decks4 decks
25%synergy
Geth's Summons
25%inclusion1 decks4 decks
25%synergy
Sign in Blood
25%inclusion1 decks4 decks
-10%synergy
Utility Artifacts
Sword of Truth and Justice
75%inclusion3 decks4 decks
74%synergy
Jet Medallion
75%inclusion3 decks4 decks
13%synergy
Whispersilk Cloak
50%inclusion2 decks4 decks
44%synergy
Lightning Greaves
50%inclusion2 decks4 decks
16%synergy
Sword of Feast and Famine
50%inclusion2 decks4 decks
48%synergy
Lashwrithe
25%inclusion1 decks4 decks
21%synergy
Wayfarer's Bauble
25%inclusion1 decks4 decks
11%synergy
Nightmare Lash
25%inclusion1 decks4 decks
23%synergy
Cauldron of Souls
25%inclusion1 decks4 decks
24%synergy
Skullclamp
25%inclusion1 decks4 decks
3%synergy
Shadowspear
25%inclusion1 decks4 decks
21%synergy
Expedition Map
25%inclusion1 decks4 decks
14%synergy
Inquisitor's Flail
25%inclusion1 decks4 decks
25%synergy
Retrofitter Foundry
25%inclusion1 decks4 decks
25%synergy
Resurrection Orb
25%inclusion1 decks4 decks
23%synergy
Surestrike Trident
25%inclusion1 decks4 decks
25%synergy
Champion's Helm
25%inclusion1 decks4 decks
23%synergy
Swiftfoot Boots
25%inclusion1 decks4 decks
-6%synergy
Tome of Legends
25%inclusion1 decks4 decks
24%synergy
Commander's Plate
25%inclusion1 decks4 decks
19%synergy
Spawning Pit
25%inclusion1 decks4 decks
24%synergy
Enchantments
Dauthi Embrace
50%inclusion2 decks4 decks
48%synergy
Greed
25%inclusion1 decks4 decks
19%synergy
Black Market
25%inclusion1 decks4 decks
5%synergy
Underworld Connections
25%inclusion1 decks4 decks
23%synergy
Glistening Oil
25%inclusion1 decks4 decks
24%synergy
Unspeakable Symbol
25%inclusion1 decks4 decks
24%synergy
Gate to Phyrexia
25%inclusion1 decks4 decks
24%synergy
Black Market Connections
25%inclusion1 decks4 decks
-0%synergy
Cover of Darkness
25%inclusion1 decks4 decks
22%synergy
Phyrexian Arena
25%inclusion1 decks4 decks
-14%synergy
Bitterblossom
25%inclusion1 decks4 decks
12%synergy
Bad Moon
25%inclusion1 decks4 decks
22%synergy
Necrogen Communion
25%inclusion1 decks4 decks
23%synergy
Super State
25%inclusion1 decks4 decks
25%synergy
Planeswalkers
Vraska, Betrayal's Sting
75%inclusion3 decks4 decks
72%synergy
Liliana of the Dark Realms
25%inclusion1 decks4 decks
11%synergy
Utility Lands
Bojuka Bog
75%inclusion3 decks4 decks
28%synergy
Inkmoth Nexus
75%inclusion3 decks4 decks
74%synergy
Spymaster's Vault
50%inclusion2 decks4 decks
40%synergy
War Room
50%inclusion2 decks4 decks
34%synergy
Shizo, Death's Storehouse
25%inclusion1 decks4 decks
15%synergy
Cabal Stronghold
25%inclusion1 decks4 decks
-9%synergy
Vault of Whispers
25%inclusion1 decks4 decks
19%synergy
Phyrexian Tower
25%inclusion1 decks4 decks
-1%synergy
Mortuary Mire
25%inclusion1 decks4 decks
12%synergy
Hall of the Bandit Lord
25%inclusion1 decks4 decks
24%synergy
The Black Gate
25%inclusion1 decks4 decks
21%synergy
Cathedral of War
25%inclusion1 decks4 decks
25%synergy
Volrath's Stronghold
25%inclusion1 decks4 decks
21%synergy
Nykthos, Shrine to Nyx
25%inclusion1 decks4 decks
-5%synergy
Minas Morgul, Dark Fortress
25%inclusion1 decks4 decks
22%synergy
Takenuma, Abandoned Mire
25%inclusion1 decks4 decks
9%synergy
Thespian's Stage
25%inclusion1 decks4 decks
20%synergy
Urborg
25%inclusion1 decks4 decks
24%synergy
Dark Depths
25%inclusion1 decks4 decks
24%synergy
Rogue's Passage
25%inclusion1 decks4 decks
5%synergy
Midgar, City of Mako
25%inclusion1 decks4 decks
15%synergy
Mana Artifacts
Glistening Sphere
75%inclusion3 decks4 decks
74%synergy
Sol Ring
75%inclusion3 decks4 decks
-10%synergy
Charcoal Diamond
50%inclusion2 decks4 decks
28%synergy
Mind Stone
50%inclusion2 decks4 decks
22%synergy
Everflowing Chalice
25%inclusion1 decks4 decks
20%synergy
Commander's Sphere
25%inclusion1 decks4 decks
17%synergy
Arcane Signet
25%inclusion1 decks4 decks
-36%synergy
Staff of Compleation
25%inclusion1 decks4 decks
23%synergy
Crowded Crypt
25%inclusion1 decks4 decks
20%synergy
Patchwork Banner
25%inclusion1 decks4 decks
21%synergy
Basalt Monolith
25%inclusion1 decks4 decks
23%synergy
Thought Vessel
25%inclusion1 decks4 decks
1%synergy
Thran Dynamo
25%inclusion1 decks4 decks
19%synergy
Phyrexian Atlas
25%inclusion1 decks4 decks
25%synergy
The Soul Stone
25%inclusion1 decks4 decks
9%synergy
Lands
Swamp
100%inclusion4 decks4 decks
5%synergy
Prismatic Vista
25%inclusion1 decks4 decks
22%synergy
Fell the Profane
25%inclusion1 decks4 decks
5%synergy
Myriad Landscape
25%inclusion1 decks4 decks
1%synergy
Agadeem's Awakening
25%inclusion1 decks4 decks
17%synergy
Verdant Catacombs
25%inclusion1 decks4 decks
21%synergy
Malakir Rebirth
25%inclusion1 decks4 decks
1%synergy
Opal Palace
25%inclusion1 decks4 decks
24%synergy
Tarnation Vista
25%inclusion1 decks4 decks
25%synergy
Abstergo Entertainment
25%inclusion1 decks4 decks
25%synergy
Bloodstained Mire
25%inclusion1 decks4 decks
21%synergy
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