Skithiryx, the Blight Dragon (Commander) - Upgraded Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #782
67decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Shredder's Technique
10%inclusion2 decks20 decks
7%synergy
Madame Null, Power Broker
8.0%inclusion2 decks25 decks
7%synergy
Ninja Teen
8.0%inclusion2 decks25 decks
7%synergy
Splinter's Technique
8.0%inclusion2 decks25 decks
6%synergy
High Synergy Cards
Infectious Inquiry
82%inclusion55 decks67 decks
79%synergy
Plague Myr
79%inclusion53 decks67 decks
78%synergy
Plague Stinger
78%inclusion52 decks67 decks
77%synergy
Karn's Bastion
73%inclusion49 decks67 decks
69%synergy
Ichor Rats
69%inclusion46 decks67 decks
66%synergy
Vraska's Fall
69%inclusion46 decks67 decks
65%synergy
Phyrexian Crusader
64%inclusion43 decks67 decks
63%synergy
Whispering Specter
61%inclusion41 decks67 decks
61%synergy
Drown in Ichor
64%inclusion43 decks67 decks
60%synergy
Hand of the Praetors
60%inclusion40 decks67 decks
59%synergy
Top Cards
Dark Ritual
76%inclusion51 decks67 decks
10%synergy
Jet Medallion
76%inclusion51 decks67 decks
15%synergy
Crypt Ghast
70%inclusion47 decks67 decks
22%synergy
Swiftfoot Boots
64%inclusion43 decks67 decks
33%synergy
Phyrexian Arena
61%inclusion41 decks67 decks
21%synergy
Sign in Blood
61%inclusion41 decks67 decks
26%synergy
Phyresis Outbreak
60%inclusion40 decks67 decks
58%synergy
Lashwrithe
58%inclusion39 decks67 decks
54%synergy
Feed the Swarm
54%inclusion36 decks67 decks
3%synergy
Night's Whisper
54%inclusion36 decks67 decks
29%synergy
Game Changers
Demonic Tutor
42%inclusion28 decks67 decks
14%synergy
Vampiric Tutor
27%inclusion18 decks67 decks
6%synergy
Necropotence
19%inclusion13 decks67 decks
5%synergy
Imperial Seal
10%inclusion7 decks67 decks
4%synergy
Ancient Tomb
9.0%inclusion6 decks67 decks
-3%synergy
The One Ring
9.0%inclusion6 decks67 decks
0%synergy
Mana Vault
9.0%inclusion6 decks67 decks
2%synergy
Bolas's Citadel
7.5%inclusion5 decks67 decks
-21%synergy
Opposition Agent
6.0%inclusion4 decks67 decks
-4%synergy
Creatures
Blightbelly Rat
46%inclusion31 decks67 decks
43%synergy
Reaper of Sheoldred
45%inclusion30 decks67 decks
44%synergy
Flensermite
39%inclusion26 decks67 decks
38%synergy
Phyrexian Obliterator
31%inclusion21 decks67 decks
20%synergy
Bilious Skulldweller
30%inclusion20 decks67 decks
29%synergy
Ichorclaw Myr
30%inclusion20 decks67 decks
29%synergy
Flesh-Eater Imp
28%inclusion19 decks67 decks
28%synergy
Core Prowler
28%inclusion19 decks67 decks
28%synergy
K'rrik, Son of Yawgmoth
28%inclusion19 decks67 decks
9%synergy
Corpse Cur
27%inclusion18 decks67 decks
26%synergy
Septic Rats
27%inclusion18 decks67 decks
25%synergy
Blightsteel Colossus
25%inclusion17 decks67 decks
25%synergy
Yawgmoth, Thran Physician
24%inclusion16 decks67 decks
14%synergy
Myr Convert
21%inclusion14 decks67 decks
20%synergy
Gulping Scraptrap
21%inclusion14 decks67 decks
20%synergy
Pestilent Syphoner
21%inclusion14 decks67 decks
20%synergy
Dread Presence
18%inclusion12 decks67 decks
4%synergy
Silent Arbiter
16%inclusion11 decks67 decks
15%synergy
Filth
16%inclusion11 decks67 decks
14%synergy
Contagious Nim
15%inclusion10 decks67 decks
15%synergy
Phyrexian Vatmother
15%inclusion10 decks67 decks
15%synergy
Dauthi Voidwalker
15%inclusion10 decks67 decks
-1%synergy
Solemn Simulacrum
13%inclusion9 decks67 decks
-9%synergy
Gray Merchant of Asphodel
13%inclusion9 decks67 decks
-38%synergy
Brass Squire
13%inclusion9 decks67 decks
13%synergy
Grafted Butcher
13%inclusion9 decks67 decks
13%synergy
Toxic Nim
13%inclusion9 decks67 decks
13%synergy
Necropede
13%inclusion9 decks67 decks
13%synergy
Nirkana Revenant
13%inclusion9 decks67 decks
2%synergy
Necroskitter
12%inclusion8 decks67 decks
9%synergy
Leaden Myr
12%inclusion8 decks67 decks
6%synergy
Blackcleave Goblin
12%inclusion8 decks67 decks
12%synergy
Dark Confidant
12%inclusion8 decks67 decks
5%synergy
Magus of the Coffers
12%inclusion8 decks67 decks
5%synergy
Phyrexian Juggernaut
10%inclusion7 decks67 decks
10%synergy
Sheoldred's Headcleaver
10%inclusion7 decks67 decks
10%synergy
Massacre Girl, Known Killer
10%inclusion7 decks67 decks
7%synergy
Vector Asp
9.0%inclusion6 decks67 decks
9%synergy
Defiler of Flesh
9.0%inclusion6 decks67 decks
5%synergy
Gwenom, Remorseless
7.8%inclusion4 decks51 decks
4%synergy
Maha, Its Feathers Night
7.5%inclusion5 decks67 decks
3%synergy
Boggart Trawler
7.5%inclusion5 decks67 decks
-1%synergy
Gix, Yawgmoth Praetor
7.5%inclusion5 decks67 decks
2%synergy
Nimraiser Paladin
7.5%inclusion5 decks67 decks
7%synergy
Sheoldred, Whispering One
7.5%inclusion5 decks67 decks
-4%synergy
Scavenger Regent
6.7%inclusion4 decks60 decks
6%synergy
Foundry Inspector
6.0%inclusion4 decks67 decks
3%synergy
Sheoldred, the Apocalypse
6.0%inclusion4 decks67 decks
-9%synergy
Phyrexian Digester
6.0%inclusion4 decks67 decks
6%synergy
Swamp Mosquito
6.0%inclusion4 decks67 decks
6%synergy
Instants
Defile
42%inclusion28 decks67 decks
5%synergy
Howl from Beyond
40%inclusion27 decks67 decks
40%synergy
Withering Torment
40%inclusion27 decks67 decks
9%synergy
Go for the Throat
37%inclusion25 decks67 decks
14%synergy
Whisper of the Dross
36%inclusion24 decks67 decks
33%synergy
Tainted Strike
36%inclusion24 decks67 decks
33%synergy
Imp's Mischief
34%inclusion23 decks67 decks
10%synergy
Malakir Rebirth
34%inclusion23 decks67 decks
12%synergy
Archenemy's Charm
30%inclusion16 decks53 decks
21%synergy
Infernal Grasp
30%inclusion20 decks67 decks
5%synergy
Cabal Ritual
28%inclusion19 decks67 decks
10%synergy
Deadly Rollick
27%inclusion18 decks67 decks
3%synergy
Fell the Profane
27%inclusion18 decks67 decks
8%synergy
Grim Affliction
25%inclusion17 decks67 decks
23%synergy
Dismember
24%inclusion16 decks67 decks
13%synergy
Sudden Spoiling
24%inclusion16 decks67 decks
15%synergy
Consuming Corruption
21%inclusion14 decks67 decks
5%synergy
Darkness
19%inclusion13 decks67 decks
9%synergy
Astarion's Thirst
18%inclusion12 decks67 decks
16%synergy
Supernatural Stamina
18%inclusion12 decks67 decks
10%synergy
Hatred
16%inclusion11 decks67 decks
15%synergy
Baleful Mastery
16%inclusion11 decks67 decks
8%synergy
Force of Despair
15%inclusion10 decks67 decks
7%synergy
Anoint with Affliction
15%inclusion10 decks67 decks
14%synergy
Snuff Out
13%inclusion9 decks67 decks
0%synergy
Hero's Downfall
13%inclusion9 decks67 decks
7%synergy
Undying Malice
12%inclusion8 decks67 decks
2%synergy
Bitter Triumph
12%inclusion8 decks67 decks
2%synergy
Cut Down
10%inclusion7 decks67 decks
6%synergy
Doom Blade
10%inclusion7 decks67 decks
3%synergy
Murder
10%inclusion7 decks67 decks
0%synergy
Fake Your Own Death
10%inclusion7 decks67 decks
3%synergy
Sheoldred's Edict
10%inclusion7 decks67 decks
-4%synergy
Armor of Shadows
10%inclusion7 decks67 decks
8%synergy
Withering Boon
10%inclusion7 decks67 decks
6%synergy
Soul Shatter
9.0%inclusion6 decks67 decks
-3%synergy
Hagra Mauling
7.5%inclusion5 decks67 decks
3%synergy
Sugar Rush
7.5%inclusion5 decks67 decks
7%synergy
Stinging Study
6.0%inclusion4 decks67 decks
3%synergy
Culling the Weak
6.0%inclusion4 decks67 decks
-10%synergy
Virulent Wound
6.0%inclusion4 decks67 decks
6%synergy
Unlikely Aid
6.0%inclusion4 decks67 decks
5%synergy
Black Sun's Twilight
6.0%inclusion4 decks67 decks
2%synergy
Undying Evil
6.0%inclusion4 decks67 decks
3%synergy
Rush of Vitality
6.0%inclusion4 decks67 decks
5%synergy
Blood Pact
6.0%inclusion4 decks67 decks
2%synergy
Sorceries
Toxic Deluge
46%inclusion31 decks67 decks
9%synergy
Crux of Fate
43%inclusion29 decks67 decks
42%synergy
Bubbling Muck
33%inclusion22 decks67 decks
17%synergy
Insatiable Avarice
33%inclusion22 decks67 decks
21%synergy
Vat Emergence
31%inclusion21 decks67 decks
30%synergy
Read the Bones
31%inclusion21 decks67 decks
14%synergy
Caress of Phyrexia
27%inclusion18 decks67 decks
26%synergy
Reanimate
27%inclusion18 decks67 decks
-13%synergy
Damnation
24%inclusion16 decks67 decks
3%synergy
Spread the Sickness
21%inclusion14 decks67 decks
20%synergy
Mutilate
21%inclusion14 decks67 decks
4%synergy
Geth's Summons
16%inclusion11 decks67 decks
16%synergy
Grim Tutor
16%inclusion11 decks67 decks
5%synergy
Blasphemous Edict
14%inclusion9 decks66 decks
-3%synergy
Diabolic Tutor
13%inclusion9 decks67 decks
-1%synergy
Black Sun's Zenith
12%inclusion8 decks67 decks
6%synergy
Exsanguinate
12%inclusion8 decks67 decks
-13%synergy
Syphon Mind
12%inclusion8 decks67 decks
-1%synergy
Profane Tutor
12%inclusion8 decks67 decks
8%synergy
Feed the Infection
12%inclusion8 decks67 decks
11%synergy
Gix's Command
12%inclusion8 decks67 decks
10%synergy
Beseech the Mirror
10%inclusion7 decks67 decks
4%synergy
Praetor's Grasp
9.0%inclusion6 decks67 decks
5%synergy
Beseech the Queen
9.0%inclusion6 decks67 decks
3%synergy
Peer into the Abyss
7.5%inclusion5 decks67 decks
-3%synergy
In Garruk's Wake
7.5%inclusion5 decks67 decks
3%synergy
Villainous Wrath
6.4%inclusion3 decks47 decks
4%synergy
Torment of Hailfire
6.0%inclusion4 decks67 decks
-10%synergy
Utility Artifacts
Sword of Truth and Justice
48%inclusion32 decks67 decks
47%synergy
Nightmare Lash
45%inclusion30 decks67 decks
42%synergy
Lightning Greaves
45%inclusion30 decks67 decks
11%synergy
Blackblade Reforged
42%inclusion28 decks67 decks
39%synergy
Contagion Clasp
40%inclusion27 decks67 decks
38%synergy
Commander's Plate
39%inclusion26 decks67 decks
33%synergy
Fireshrieker
36%inclusion24 decks67 decks
34%synergy
Contagion Engine
34%inclusion23 decks67 decks
32%synergy
Whispersilk Cloak
33%inclusion22 decks67 decks
27%synergy
Champion's Helm
33%inclusion22 decks67 decks
31%synergy
Sword of the Animist
31%inclusion21 decks67 decks
28%synergy
Shadowspear
27%inclusion18 decks67 decks
23%synergy
Hero's Blade
24%inclusion16 decks67 decks
23%synergy
Leyline Axe
21%inclusion14 decks66 decks
20%synergy
Mithril Coat
19%inclusion13 decks67 decks
14%synergy
The Darkness Crystal
19%inclusion11 decks57 decks
-1%synergy
Pact Weapon
18%inclusion12 decks67 decks
16%synergy
Sword of Feast and Famine
18%inclusion12 decks67 decks
16%synergy
Hammer of Nazahn
18%inclusion12 decks67 decks
17%synergy
Wayfarer's Bauble
16%inclusion11 decks67 decks
1%synergy
Expedition Map
16%inclusion11 decks67 decks
4%synergy
Cranial Plating
16%inclusion11 decks67 decks
13%synergy
Brotherhood Regalia
16%inclusion11 decks67 decks
14%synergy
Basilisk Collar
16%inclusion11 decks67 decks
14%synergy
Genji Glove
15%inclusion8 decks55 decks
13%synergy
Trailblazer's Boots
13%inclusion9 decks67 decks
11%synergy
Doc Ock's Tentacles
13%inclusion6 decks47 decks
13%synergy
Throne of Geth
10%inclusion7 decks67 decks
10%synergy
Inquisitor's Flail
10%inclusion7 decks67 decks
10%synergy
Darksteel Plate
10%inclusion7 decks67 decks
9%synergy
Grafted Wargear
10%inclusion7 decks67 decks
10%synergy
Sword of Vengeance
10%inclusion7 decks67 decks
10%synergy
Grafted Exoskeleton
9.0%inclusion6 decks67 decks
8%synergy
Silver Shroud Costume
9.0%inclusion6 decks67 decks
8%synergy
Sword of Forge and Frontier
9.0%inclusion6 decks67 decks
8%synergy
Sword of Fire and Ice
7.5%inclusion5 decks67 decks
7%synergy
Manifold Key
7.5%inclusion5 decks67 decks
6%synergy
O-Naginata
7.5%inclusion5 decks67 decks
7%synergy
Prowler's Helm
7.5%inclusion5 decks67 decks
7%synergy
Vorpal Sword
7.5%inclusion5 decks67 decks
4%synergy
Helm of the Host
7.5%inclusion5 decks67 decks
6%synergy
Bontu's Monument
7.5%inclusion5 decks67 decks
-21%synergy
Sword of Light and Shadow
7.5%inclusion5 decks67 decks
7%synergy
Loxodon Warhammer
7.5%inclusion5 decks67 decks
6%synergy
Buster Sword
7.0%inclusion4 decks57 decks
6%synergy
Pip-Boy 3000
6.0%inclusion4 decks67 decks
6%synergy
Lavaspur Boots
6.0%inclusion4 decks67 decks
4%synergy
Skullclamp
6.0%inclusion4 decks67 decks
-16%synergy
Conqueror's Flail
6.0%inclusion4 decks67 decks
5%synergy
Mask of Avacyn
6.0%inclusion4 decks67 decks
5%synergy
Enchantments
Necrogen Communion
46%inclusion31 decks67 decks
44%synergy
Black Market Connections
33%inclusion22 decks67 decks
9%synergy
Kaya's Ghostform
28%inclusion19 decks67 decks
18%synergy
Unspeakable Symbol
25%inclusion17 decks67 decks
24%synergy
Bad Moon
18%inclusion12 decks67 decks
15%synergy
No Mercy
18%inclusion12 decks67 decks
11%synergy
Animate Dead
10%inclusion7 decks67 decks
-7%synergy
Phyresis
9.0%inclusion6 decks67 decks
7%synergy
Dauthi Embrace
9.0%inclusion6 decks67 decks
7%synergy
Super State
7.5%inclusion4 decks53 decks
7%synergy
Black Market
7.5%inclusion5 decks67 decks
-14%synergy
Endless Scream
7.5%inclusion5 decks67 decks
7%synergy
Mornsong Aria
7.4%inclusion2 decks27 decks
6%synergy
Greed
6.0%inclusion4 decks67 decks
-1%synergy
Shade's Form
6.0%inclusion4 decks67 decks
5%synergy
Corpses of the Lost
6.0%inclusion4 decks67 decks
5%synergy
Fungal Fortitude
6.0%inclusion4 decks67 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion31 decks67 decks
44%synergy
Liliana of the Dark Realms
30%inclusion20 decks67 decks
16%synergy
Utility Lands
Rogue's Passage
73%inclusion49 decks67 decks
54%synergy
Cabal Coffers
72%inclusion48 decks67 decks
17%synergy
Bojuka Bog
55%inclusion37 decks67 decks
8%synergy
Shizo, Death's Storehouse
51%inclusion34 decks67 decks
41%synergy
Urborg, Tomb of Yawgmoth
51%inclusion34 decks67 decks
13%synergy
Inkmoth Nexus
46%inclusion31 decks67 decks
45%synergy
Cabal Stronghold
39%inclusion26 decks67 decks
4%synergy
War Room
33%inclusion22 decks67 decks
17%synergy
Castle Locthwain
27%inclusion18 decks67 decks
10%synergy
Cathedral of War
25%inclusion17 decks67 decks
25%synergy
Urza's Saga
19%inclusion13 decks67 decks
11%synergy
Command Beacon
19%inclusion13 decks67 decks
11%synergy
The Black Gate
18%inclusion12 decks67 decks
14%synergy
Minas Morgul, Dark Fortress
18%inclusion12 decks67 decks
15%synergy
Nykthos, Shrine to Nyx
16%inclusion11 decks67 decks
-13%synergy
Witch's Cottage
15%inclusion10 decks67 decks
-10%synergy
Mortuary Mire
13%inclusion9 decks67 decks
0%synergy
Spymaster's Vault
13%inclusion9 decks67 decks
4%synergy
Temple of the False God
10%inclusion7 decks67 decks
3%synergy
Reliquary Tower
10%inclusion7 decks67 decks
-20%synergy
Phyrexian Tower
9.0%inclusion6 decks67 decks
-16%synergy
Buried Ruin
9.0%inclusion6 decks67 decks
4%synergy
Ebon Stronghold
7.5%inclusion5 decks67 decks
6%synergy
Peat Bog
7.5%inclusion5 decks67 decks
6%synergy
Barren Moor
7.5%inclusion5 decks67 decks
-2%synergy
Maze of Ith
7.5%inclusion5 decks67 decks
4%synergy
Vesuva
6.0%inclusion4 decks67 decks
3%synergy
Deserted Temple
6.0%inclusion4 decks67 decks
2%synergy
Tyrite Sanctum
6.0%inclusion4 decks67 decks
5%synergy
Volrath's Stronghold
6.0%inclusion4 decks67 decks
2%synergy
Thespian's Stage
6.0%inclusion4 decks67 decks
1%synergy
Mana Artifacts
Sol Ring
93%inclusion62 decks67 decks
7%synergy
Arcane Signet
60%inclusion40 decks67 decks
-2%synergy
Glistening Sphere
40%inclusion27 decks67 decks
39%synergy
Mind Stone
37%inclusion25 decks67 decks
8%synergy
Staff of Compleation
33%inclusion22 decks67 decks
31%synergy
Charcoal Diamond
25%inclusion17 decks67 decks
3%synergy
Heraldic Banner
24%inclusion16 decks67 decks
18%synergy
Thought Vessel
18%inclusion12 decks67 decks
-8%synergy
The Soul Stone
17%inclusion9 decks52 decks
3%synergy
Fellwar Stone
15%inclusion10 decks67 decks
1%synergy
Everflowing Chalice
12%inclusion8 decks67 decks
6%synergy
Lotus Petal
10%inclusion7 decks67 decks
3%synergy
Thran Dynamo
9.0%inclusion6 decks67 decks
3%synergy
Throne of Eldraine
9.0%inclusion6 decks67 decks
-1%synergy
Caged Sun
7.5%inclusion5 decks67 decks
-4%synergy
Commander's Sphere
7.5%inclusion5 decks67 decks
-1%synergy
Mox Opal
7.5%inclusion5 decks67 decks
4%synergy
Patchwork Banner
7.5%inclusion5 decks67 decks
3%synergy
Bender's Waterskin
6.0%inclusion3 decks50 decks
5%synergy
Prismatic Lens
6.0%inclusion4 decks67 decks
4%synergy
Hedron Archive
6.0%inclusion4 decks67 decks
2%synergy
Worn Powerstone
6.0%inclusion4 decks67 decks
2%synergy
Phyrexian Atlas
6.0%inclusion4 decks67 decks
6%synergy
Lands
Swamp
96%inclusion64 decks67 decks
0%synergy
Malakir Rebirth
34%inclusion23 decks67 decks
12%synergy
Myriad Landscape
33%inclusion22 decks67 decks
7%synergy
Fell the Profane
27%inclusion18 decks67 decks
8%synergy
Mirrex
19%inclusion13 decks67 decks
19%synergy
Urza's Cave
13%inclusion9 decks67 decks
5%synergy
Cavern of Souls
12%inclusion8 decks67 decks
5%synergy
Hagra Mauling
7.5%inclusion5 decks67 decks
3%synergy
Boggart Trawler
7.5%inclusion5 decks67 decks
-1%synergy
Opal Palace
7.5%inclusion5 decks67 decks
7%synergy
The Seedcore
6.0%inclusion4 decks67 decks
6%synergy
Plaza of Heroes
6.0%inclusion4 decks67 decks
5%synergy
Evolving Wilds
6.0%inclusion4 decks67 decks
2%synergy
Marsh Flats
6.0%inclusion4 decks67 decks
3%synergy
Polluted Delta
6.0%inclusion4 decks67 decks
2%synergy
Terramorphic Expanse
6.0%inclusion4 decks67 decks
3%synergy
Verdant Catacombs
6.0%inclusion4 decks67 decks
3%synergy
Bloodstained Mire
6.0%inclusion4 decks67 decks
2%synergy
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