Ayara, First of Locthwain (Commander) - Lifedrain

Ayara, First of Locthwain
Rank #379
178decks
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Josh Nelson
Jul 16, 2026
Josh Nelson
Ten Combos for Your Next Monocolor Commander Decks
Ten mono-color Commander combos, two per color, from the Pickles lock to Squirrel Nest + Earthcraft, that you can drop into your next builds.
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Top Cards
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Instants
Sorceries
Utility Artifacts
Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
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Hammerhead, Maggia Boss
1.9%inclusion1 decks52 decks
1%synergy
Undead Hand Ninja
1.9%inclusion1 decks52 decks
1%synergy
Red Room Recruit
1.9%inclusion1 decks52 decks
1%synergy
Construct a Cosmic Cube
1.9%inclusion1 decks53 decks
0%synergy
High Synergy Cards
Ophiomancer
71%inclusion126 decks178 decks
53%synergy
Zulaport Cutthroat
68%inclusion121 decks178 decks
45%synergy
Abhorrent Overlord
48%inclusion86 decks178 decks
44%synergy
Jadar, Ghoulcaller of Nephalia
54%inclusion96 decks178 decks
43%synergy
Reassembling Skeleton
58%inclusion104 decks178 decks
41%synergy
Bitterblossom
52%inclusion93 decks178 decks
39%synergy
Endrek Sahr, Master Breeder
45%inclusion80 decks178 decks
38%synergy
Pitiless Plunderer
55%inclusion98 decks178 decks
35%synergy
Starscape Cleric
38%inclusion67 decks178 decks
34%synergy
Army of the Damned
38%inclusion67 decks178 decks
33%synergy
Top Cards
Gray Merchant of Asphodel
83%inclusion147 decks178 decks
32%synergy
Dark Ritual
70%inclusion124 decks178 decks
3%synergy
Jet Medallion
69%inclusion122 decks178 decks
6%synergy
Crypt Ghast
65%inclusion115 decks178 decks
18%synergy
Blood Artist
61%inclusion108 decks178 decks
29%synergy
Bontu's Monument
60%inclusion106 decks178 decks
31%synergy
Toxic Deluge
51%inclusion91 decks178 decks
14%synergy
Skullclamp
51%inclusion90 decks178 decks
28%synergy
Feed the Swarm
50%inclusion89 decks178 decks
-0%synergy
Victimize
49%inclusion87 decks178 decks
21%synergy
Game Changers
Bolas's Citadel
48%inclusion86 decks178 decks
20%synergy
Demonic Tutor
22%inclusion39 decks178 decks
-5%synergy
Necropotence
18%inclusion32 decks178 decks
4%synergy
Orcish Bowmasters
17%inclusion31 decks178 decks
4%synergy
Vampiric Tutor
16%inclusion28 decks178 decks
-5%synergy
The One Ring
6.7%inclusion12 decks178 decks
-3%synergy
Ancient Tomb
5.6%inclusion10 decks178 decks
-6%synergy
Opposition Agent
5.1%inclusion9 decks178 decks
-4%synergy
Creatures
Syr Konrad, the Grim
47%inclusion84 decks178 decks
27%synergy
Viscera Seer
47%inclusion84 decks178 decks
30%synergy
Braids, Arisen Nightmare
47%inclusion84 decks178 decks
28%synergy
Morbid Opportunist
45%inclusion80 decks178 decks
21%synergy
Bloodghast
40%inclusion72 decks178 decks
28%synergy
Marauding Blight-Priest
39%inclusion70 decks178 decks
32%synergy
Gravecrawler
35%inclusion63 decks178 decks
20%synergy
Warren Soultrader
35%inclusion63 decks178 decks
22%synergy
Witch of the Moors
35%inclusion62 decks178 decks
31%synergy
Vito, Thorn of the Dusk Rose
35%inclusion62 decks178 decks
24%synergy
Grave Titan
33%inclusion59 decks178 decks
26%synergy
Nine-Lives Familiar
32%inclusion57 decks178 decks
24%synergy
Bitterbloom Bearer
31%inclusion43 decks138 decks
24%synergy
Bloodletter of Aclazotz
31%inclusion55 decks178 decks
20%synergy
Mirkwood Bats
31%inclusion55 decks178 decks
23%synergy
Chittering Witch
31%inclusion55 decks178 decks
27%synergy
Lord Skitter, Sewer King
30%inclusion53 decks178 decks
22%synergy
Priest of Forgotten Gods
28%inclusion50 decks178 decks
20%synergy
Massacre Wurm
28%inclusion49 decks178 decks
10%synergy
Nether Traitor
27%inclusion48 decks178 decks
18%synergy
Carrion Feeder
26%inclusion47 decks178 decks
14%synergy
Sengir Autocrat
25%inclusion44 decks178 decks
23%synergy
Midnight Reaper
25%inclusion44 decks178 decks
16%synergy
Scheming Silvertongue
24%inclusion20 decks82 decks
18%synergy
Marionette Apprentice
24%inclusion43 decks178 decks
13%synergy
Ghoulcaller Gisa
23%inclusion41 decks178 decks
18%synergy
Accursed Marauder
22%inclusion40 decks178 decks
1%synergy
Great Unclean One
22%inclusion39 decks178 decks
20%synergy
Grim Haruspex
22%inclusion39 decks178 decks
13%synergy
Yawgmoth, Thran Physician
21%inclusion38 decks178 decks
11%synergy
Plaguecrafter
21%inclusion38 decks178 decks
1%synergy
Umbral Collar Zealot
21%inclusion32 decks153 decks
13%synergy
K'rrik, Son of Yawgmoth
21%inclusion37 decks178 decks
1%synergy
Sheoldred, the Apocalypse
19%inclusion34 decks178 decks
4%synergy
Enduring Tenacity
19%inclusion34 decks178 decks
11%synergy
Grim Servant
19%inclusion33 decks178 decks
14%synergy
Dread Presence
19%inclusion33 decks178 decks
5%synergy
Murderous Rider
18%inclusion32 decks178 decks
12%synergy
Boggart Trawler
17%inclusion31 decks178 decks
8%synergy
Ogre Slumlord
17%inclusion30 decks178 decks
7%synergy
Veinwitch Coven
17%inclusion30 decks178 decks
15%synergy
Timeline Culler
16%inclusion25 decks153 decks
12%synergy
Dark Confidant
16%inclusion29 decks178 decks
9%synergy
Vraan, Executioner Thane
15%inclusion27 decks178 decks
12%synergy
Mikaeus, the Unhallowed
15%inclusion27 decks178 decks
8%synergy
Ravenous Chupacabra
15%inclusion26 decks178 decks
10%synergy
Bloodthirsty Conqueror
14%inclusion25 decks175 decks
5%synergy
Erebos, Bleak-Hearted
14%inclusion25 decks178 decks
12%synergy
Vindictive Vampire
14%inclusion25 decks178 decks
12%synergy
Sephiroth, Fabled SOLDIER
14%inclusion22 decks162 decks
8%synergy
Instants
Defile
38%inclusion68 decks178 decks
3%synergy
Withering Torment
38%inclusion66 decks175 decks
6%synergy
Tragic Slip
37%inclusion65 decks178 decks
17%synergy
Malakir Rebirth
36%inclusion64 decks178 decks
13%synergy
Village Rites
35%inclusion62 decks178 decks
9%synergy
Szat's Will
27%inclusion48 decks178 decks
25%synergy
Fell the Profane
25%inclusion45 decks178 decks
6%synergy
Deadly Rollick
21%inclusion38 decks178 decks
-4%synergy
Deadly Dispute
21%inclusion37 decks178 decks
-6%synergy
Imp's Mischief
20%inclusion36 decks178 decks
-5%synergy
Saw in Half
20%inclusion36 decks178 decks
11%synergy
Corrupted Conviction
19%inclusion34 decks178 decks
7%synergy
Culling the Weak
17%inclusion31 decks178 decks
-0%synergy
Infernal Grasp
17%inclusion31 decks178 decks
-8%synergy
Go for the Throat
15%inclusion26 decks178 decks
-8%synergy
Consuming Corruption
15%inclusion26 decks178 decks
-1%synergy
Flare of Malice
15%inclusion26 decks178 decks
1%synergy
Not Dead After All
13%inclusion24 decks178 decks
2%synergy
Plumb the Forbidden
13%inclusion23 decks178 decks
9%synergy
Soul Shatter
12%inclusion22 decks178 decks
1%synergy
Undying Malice
12%inclusion22 decks178 decks
2%synergy
Archenemy's Charm
12%inclusion18 decks153 decks
3%synergy
Force of Despair
11%inclusion20 decks178 decks
4%synergy
Snuff Out
11%inclusion20 decks178 decks
-2%synergy
Bitter Triumph
10%inclusion18 decks178 decks
0%synergy
Entomb
9.0%inclusion16 decks178 decks
-4%synergy
Fake Your Own Death
8.4%inclusion15 decks178 decks
1%synergy
Baleful Mastery
8.4%inclusion15 decks178 decks
0%synergy
Feign Death
8.4%inclusion15 decks178 decks
0%synergy
Dismember
8.4%inclusion15 decks178 decks
-2%synergy
Cabal Ritual
7.9%inclusion14 decks178 decks
-11%synergy
Murder
7.3%inclusion13 decks178 decks
-2%synergy
Sudden Spoiling
7.3%inclusion13 decks178 decks
-1%synergy
Darkness
6.7%inclusion12 decks178 decks
-4%synergy
Hagra Mauling
5.6%inclusion10 decks178 decks
1%synergy
Rise of the Dread Marn
5.6%inclusion10 decks178 decks
4%synergy
Sheoldred's Edict
5.6%inclusion10 decks178 decks
-9%synergy
Hero's Downfall
5.1%inclusion9 decks178 decks
-2%synergy
Fatal Push
5.1%inclusion9 decks178 decks
2%synergy
Supernatural Stamina
5.1%inclusion9 decks178 decks
-3%synergy
Lethal Scheme
5.1%inclusion9 decks178 decks
2%synergy
Sorceries
Reanimate
45%inclusion80 decks178 decks
4%synergy
Exsanguinate
37%inclusion65 decks178 decks
12%synergy
Plague of Vermin
34%inclusion61 decks178 decks
32%synergy
Sign in Blood
30%inclusion53 decks178 decks
-5%synergy
Damnation
20%inclusion36 decks178 decks
0%synergy
Diabolic Intent
19%inclusion34 decks178 decks
4%synergy
Mutilate
18%inclusion32 decks178 decks
2%synergy
Blasphemous Edict
18%inclusion31 decks175 decks
2%synergy
Night's Whisper
16%inclusion28 decks178 decks
-9%synergy
Dread Return
15%inclusion26 decks178 decks
3%synergy
Insatiable Avarice
15%inclusion26 decks178 decks
4%synergy
Rise of the Dark Realms
15%inclusion26 decks178 decks
1%synergy
Bubbling Muck
13%inclusion24 decks178 decks
-2%synergy
Unearth
12%inclusion22 decks178 decks
3%synergy
Torment of Hailfire
11%inclusion20 decks178 decks
-4%synergy
Agadeem's Awakening
10%inclusion18 decks178 decks
2%synergy
Read the Bones
10%inclusion18 decks178 decks
-6%synergy
Living Death
10%inclusion18 decks178 decks
-0%synergy
Diabolic Tutor
10%inclusion17 decks178 decks
-4%synergy
Persist
7.9%inclusion14 decks178 decks
4%synergy
Decorum Dissertation
7.3%inclusion6 decks82 decks
1%synergy
Coiling Rebirth
7.3%inclusion13 decks178 decks
6%synergy
Grim Tutor
7.3%inclusion13 decks178 decks
-4%synergy
Lively Dirge
6.7%inclusion12 decks178 decks
3%synergy
Buried Alive
6.7%inclusion12 decks178 decks
-6%synergy
Syphon Mind
5.6%inclusion10 decks178 decks
-6%synergy
Deadly Tempest
5.1%inclusion9 decks178 decks
3%synergy
Utility Artifacts
Ashnod's Altar
33%inclusion58 decks178 decks
13%synergy
Phyrexian Altar
32%inclusion57 decks178 decks
18%synergy
Lightning Greaves
18%inclusion32 decks178 decks
-16%synergy
Swiftfoot Boots
17%inclusion31 decks178 decks
-14%synergy
The Darkness Crystal
17%inclusion28 decks162 decks
-3%synergy
Expedition Map
15%inclusion27 decks178 decks
4%synergy
Panharmonicon
13%inclusion23 decks178 decks
11%synergy
Wayfarer's Bauble
12%inclusion21 decks178 decks
-3%synergy
Desecrated Tomb
5.1%inclusion9 decks178 decks
3%synergy
Sensei's Divining Top
5.1%inclusion9 decks178 decks
-3%synergy
Wishclaw Talisman
5.1%inclusion9 decks178 decks
-2%synergy
Enchantments
Bastion of Remembrance
41%inclusion73 decks178 decks
24%synergy
Phyrexian Arena
38%inclusion67 decks178 decks
-2%synergy
Dreadhorde Invasion
34%inclusion61 decks178 decks
26%synergy
Grave Pact
34%inclusion61 decks178 decks
15%synergy
The Meathook Massacre
32%inclusion57 decks178 decks
15%synergy
Black Market
24%inclusion42 decks178 decks
3%synergy
Sanguine Bond
22%inclusion40 decks178 decks
11%synergy
Dark Prophecy
22%inclusion40 decks178 decks
19%synergy
Exquisite Blood
20%inclusion36 decks178 decks
7%synergy
Black Market Connections
20%inclusion36 decks178 decks
-4%synergy
Animate Dead
19%inclusion33 decks178 decks
1%synergy
Dictate of Erebos
15%inclusion27 decks178 decks
4%synergy
Phyrexian Reclamation
15%inclusion26 decks178 decks
5%synergy
Funeral Room // Awakening Hall
13%inclusion23 decks175 decks
9%synergy
Ghoulish Procession
12%inclusion21 decks178 decks
9%synergy
Chthonian Nightmare
11%inclusion19 decks178 decks
7%synergy
Meathook Massacre II
10%inclusion18 decks175 decks
4%synergy
Vampiric Rites
10%inclusion18 decks178 decks
4%synergy
Underworld Dreams
9.0%inclusion16 decks178 decks
3%synergy
Case of the Stashed Skeleton
8.4%inclusion15 decks178 decks
6%synergy
Bloodchief Ascension
8.4%inclusion15 decks178 decks
-1%synergy
Wound Reflection
7.9%inclusion14 decks178 decks
4%synergy
Oubliette
7.9%inclusion14 decks178 decks
5%synergy
Blight Mound
7.3%inclusion13 decks178 decks
5%synergy
Oversold Cemetery
6.7%inclusion12 decks178 decks
2%synergy
Open the Graves
6.2%inclusion11 decks178 decks
3%synergy
Kaya's Ghostform
5.6%inclusion10 decks178 decks
-4%synergy
No Mercy
5.6%inclusion10 decks178 decks
-2%synergy
Grave Venerations
5.1%inclusion6 decks117 decks
2%synergy
Ripples of Undeath
5.1%inclusion9 decks178 decks
-1%synergy
Contamination
5.1%inclusion9 decks178 decks
2%synergy
Planeswalkers
Liliana, Dreadhorde General
37%inclusion65 decks178 decks
23%synergy
Tevesh Szat, Doom of Fools
13%inclusion23 decks178 decks
10%synergy
Lolth, Spider Queen
13%inclusion23 decks178 decks
11%synergy
Liliana of the Dark Realms
11%inclusion19 decks178 decks
-3%synergy
Utility Lands
Cabal Coffers
67%inclusion119 decks178 decks
12%synergy
Bojuka Bog
57%inclusion101 decks178 decks
10%synergy
Witch's Cottage
52%inclusion92 decks178 decks
27%synergy
Nykthos, Shrine to Nyx
42%inclusion75 decks178 decks
12%synergy
Cabal Stronghold
40%inclusion72 decks178 decks
6%synergy
Phyrexian Tower
39%inclusion70 decks178 decks
13%synergy
Castle Locthwain
37%inclusion66 decks178 decks
20%synergy
Urborg, Tomb of Yawgmoth
37%inclusion65 decks178 decks
-1%synergy
Mortuary Mire
29%inclusion51 decks178 decks
16%synergy
Crypt of Agadeem
21%inclusion37 decks178 decks
9%synergy
Takenuma, Abandoned Mire
18%inclusion32 decks178 decks
2%synergy
Spymaster's Vault
17%inclusion30 decks178 decks
7%synergy
Barad-dûr
17%inclusion30 decks178 decks
13%synergy
Reliquary Tower
17%inclusion30 decks178 decks
-13%synergy
High Market
16%inclusion28 decks178 decks
8%synergy
Westvale Abbey
14%inclusion25 decks178 decks
8%synergy
War Room
14%inclusion25 decks178 decks
-2%synergy
Leechridden Swamp
14%inclusion25 decks178 decks
11%synergy
Midgar, City of Mako
12%inclusion20 decks161 decks
2%synergy
Barren Moor
12%inclusion22 decks178 decks
3%synergy
Memorial to Folly
10%inclusion17 decks178 decks
6%synergy
Susur Secundi, Void Altar
8.5%inclusion13 decks153 decks
1%synergy
Deserted Temple
6.7%inclusion12 decks178 decks
3%synergy
Thespian's Stage
6.7%inclusion12 decks178 decks
2%synergy
Temple of the False God
5.6%inclusion10 decks178 decks
-2%synergy
Ghost Quarter
5.1%inclusion9 decks178 decks
3%synergy
Polluted Mire
5.1%inclusion9 decks178 decks
2%synergy
Mana Artifacts
Sol Ring
68%inclusion121 decks178 decks
-17%synergy
Arcane Signet
51%inclusion91 decks178 decks
-10%synergy
Charcoal Diamond
21%inclusion37 decks178 decks
-1%synergy
Crowded Crypt
20%inclusion36 decks178 decks
15%synergy
Nyx Lotus
15%inclusion27 decks178 decks
9%synergy
The Soul Stone
14%inclusion21 decks151 decks
-2%synergy
Throne of Eldraine
11%inclusion20 decks178 decks
2%synergy
Thought Vessel
11%inclusion19 decks178 decks
-14%synergy
Fellwar Stone
7.9%inclusion14 decks178 decks
-6%synergy
Mind Stone
6.2%inclusion11 decks178 decks
-22%synergy
Caged Sun
5.6%inclusion10 decks178 decks
-5%synergy
Lands
Swamp
95%inclusion169 decks178 decks
-0%synergy
Malakir Rebirth
36%inclusion64 decks178 decks
13%synergy
Fell the Profane
25%inclusion45 decks178 decks
6%synergy
Myriad Landscape
20%inclusion36 decks178 decks
-4%synergy
Boggart Trawler
17%inclusion31 decks178 decks
8%synergy
Urza's Cave
11%inclusion20 decks178 decks
3%synergy
Agadeem's Awakening
10%inclusion18 decks178 decks
2%synergy
Snow-Covered Swamp
6.7%inclusion12 decks178 decks
0%synergy
Hagra Mauling
5.6%inclusion10 decks178 decks
1%synergy
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