Ayara, First of Locthwain (Commander) - Upgraded Lifedrain

Ayara, First of Locthwain
Rank #379
52decks
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Josh Nelson
Jul 16, 2026
Josh Nelson
Ten Combos for Your Next Monocolor Commander Decks
Ten mono-color Commander combos, two per color, from the Pickles lock to Squirrel Nest + Earthcraft, that you can drop into your next builds.
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Sorceries
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Enchantments
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Utility Lands
Mana Artifacts
Lands
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The Sackville-Bagginses
5.0%inclusion1 decks20 decks
4%synergy
The Master of Lake-town
4.8%inclusion1 decks21 decks
1%synergy
Gollum, Riddle Master
4.5%inclusion1 decks22 decks
4%synergy
High Synergy Cards
Jadar, Ghoulcaller of Nephalia
69%inclusion36 decks52 decks
58%synergy
Ophiomancer
75%inclusion39 decks52 decks
57%synergy
Abhorrent Overlord
58%inclusion30 decks52 decks
54%synergy
Bitterblossom
56%inclusion29 decks52 decks
43%synergy
Gray Merchant of Asphodel
90%inclusion47 decks52 decks
40%synergy
Viscera Seer
58%inclusion30 decks52 decks
40%synergy
Reassembling Skeleton
56%inclusion29 decks52 decks
38%synergy
Pitiless Plunderer
58%inclusion30 decks52 decks
37%synergy
Zulaport Cutthroat
60%inclusion31 decks52 decks
36%synergy
Bitterbloom Bearer
43%inclusion19 decks44 decks
36%synergy
Top Cards
Dark Ritual
75%inclusion39 decks52 decks
8%synergy
Jet Medallion
75%inclusion39 decks52 decks
13%synergy
Crypt Ghast
75%inclusion39 decks52 decks
28%synergy
Toxic Deluge
62%inclusion32 decks52 decks
25%synergy
Feed the Swarm
58%inclusion30 decks52 decks
7%synergy
Braids, Arisen Nightmare
56%inclusion29 decks52 decks
36%synergy
Bontu's Monument
52%inclusion27 decks52 decks
24%synergy
Syr Konrad, the Grim
50%inclusion26 decks52 decks
30%synergy
Blood Artist
48%inclusion25 decks52 decks
16%synergy
Reanimate
46%inclusion24 decks52 decks
5%synergy
Game Changers
Bolas's Citadel
58%inclusion30 decks52 decks
30%synergy
Demonic Tutor
19%inclusion10 decks52 decks
-8%synergy
Necropotence
15%inclusion8 decks52 decks
1%synergy
Orcish Bowmasters
15%inclusion8 decks52 decks
3%synergy
Braids, Cabal Minion
7.7%inclusion4 decks52 decks
4%synergy
Vampiric Tutor
5.8%inclusion3 decks52 decks
-15%synergy
Creatures
Endrek Sahr, Master Breeder
42%inclusion22 decks52 decks
36%synergy
Warren Soultrader
42%inclusion22 decks52 decks
28%synergy
Bloodletter of Aclazotz
38%inclusion20 decks52 decks
28%synergy
Morbid Opportunist
38%inclusion20 decks52 decks
14%synergy
Starscape Cleric
38%inclusion20 decks52 decks
35%synergy
Gravecrawler
38%inclusion20 decks52 decks
23%synergy
Marauding Blight-Priest
37%inclusion19 decks52 decks
30%synergy
Bloodghast
37%inclusion19 decks52 decks
24%synergy
Massacre Wurm
35%inclusion18 decks52 decks
17%synergy
Chittering Witch
33%inclusion17 decks52 decks
29%synergy
K'rrik, Son of Yawgmoth
33%inclusion17 decks52 decks
13%synergy
Scheming Silvertongue
31%inclusion10 decks32 decks
25%synergy
Vito, Thorn of the Dusk Rose
31%inclusion16 decks52 decks
20%synergy
Nine-Lives Familiar
31%inclusion16 decks52 decks
22%synergy
Grim Servant
31%inclusion16 decks52 decks
26%synergy
Grave Titan
29%inclusion15 decks52 decks
22%synergy
Sengir Autocrat
29%inclusion15 decks52 decks
27%synergy
Accursed Marauder
27%inclusion14 decks52 decks
5%synergy
Yawgmoth, Thran Physician
27%inclusion14 decks52 decks
17%synergy
Marionette Apprentice
27%inclusion14 decks52 decks
16%synergy
Lord Skitter, Sewer King
27%inclusion14 decks52 decks
19%synergy
Mirkwood Bats
25%inclusion13 decks52 decks
17%synergy
Nether Traitor
25%inclusion13 decks52 decks
16%synergy
Moseo, Vein's New Dean
25%inclusion8 decks32 decks
22%synergy
Carrion Feeder
25%inclusion13 decks52 decks
13%synergy
Witch of the Moors
25%inclusion13 decks52 decks
21%synergy
Dark Confidant
25%inclusion13 decks52 decks
17%synergy
Boggart Trawler
23%inclusion12 decks52 decks
14%synergy
Priest of Forgotten Gods
23%inclusion12 decks52 decks
14%synergy
Ogre Slumlord
23%inclusion12 decks52 decks
14%synergy
Midnight Reaper
23%inclusion12 decks52 decks
15%synergy
Darkstar Augur
23%inclusion12 decks52 decks
21%synergy
Umbral Collar Zealot
22%inclusion10 decks46 decks
13%synergy
Enduring Tenacity
21%inclusion11 decks52 decks
13%synergy
Ravenous Chupacabra
21%inclusion11 decks52 decks
17%synergy
Hoarding Broodlord
19%inclusion10 decks52 decks
15%synergy
Veinwitch Coven
19%inclusion10 decks52 decks
17%synergy
Grim Haruspex
19%inclusion10 decks52 decks
11%synergy
Timeline Culler
17%inclusion8 decks46 decks
13%synergy
Vindictive Vampire
17%inclusion9 decks52 decks
15%synergy
Great Unclean One
17%inclusion9 decks52 decks
15%synergy
Pawn of Ulamog
15%inclusion8 decks52 decks
5%synergy
Dread Presence
15%inclusion8 decks52 decks
2%synergy
Murderous Rider
15%inclusion8 decks52 decks
10%synergy
Ghoulcaller Gisa
15%inclusion8 decks52 decks
11%synergy
Dauthi Voidwalker
15%inclusion8 decks52 decks
-0%synergy
Grave Researcher
14%inclusion5 decks35 decks
6%synergy
Sephiroth, Fabled SOLDIER
14%inclusion7 decks50 decks
9%synergy
Plaguecrafter
13%inclusion7 decks52 decks
-6%synergy
Erebos, God of the Dead
13%inclusion7 decks52 decks
9%synergy
Instants
Malakir Rebirth
48%inclusion25 decks52 decks
24%synergy
Withering Torment
44%inclusion23 decks52 decks
12%synergy
Defile
42%inclusion22 decks52 decks
7%synergy
Village Rites
38%inclusion20 decks52 decks
13%synergy
Tragic Slip
38%inclusion20 decks52 decks
20%synergy
Fell the Profane
37%inclusion19 decks52 decks
17%synergy
Deadly Dispute
33%inclusion17 decks52 decks
5%synergy
Szat's Will
33%inclusion17 decks52 decks
30%synergy
Saw in Half
25%inclusion13 decks52 decks
16%synergy
Consuming Corruption
23%inclusion12 decks52 decks
8%synergy
Imp's Mischief
21%inclusion11 decks52 decks
-4%synergy
Culling the Weak
21%inclusion11 decks52 decks
3%synergy
Force of Despair
19%inclusion10 decks52 decks
12%synergy
Not Dead After All
17%inclusion9 decks52 decks
6%synergy
Flare of Malice
17%inclusion9 decks52 decks
4%synergy
Undying Malice
17%inclusion9 decks52 decks
7%synergy
Snuff Out
15%inclusion8 decks52 decks
1%synergy
Soul Shatter
15%inclusion8 decks52 decks
4%synergy
Feign Death
15%inclusion8 decks52 decks
7%synergy
Archenemy's Charm
15%inclusion7 decks46 decks
6%synergy
Deadly Rollick
13%inclusion7 decks52 decks
-12%synergy
Plumb the Forbidden
13%inclusion7 decks52 decks
9%synergy
Cabal Ritual
12%inclusion6 decks52 decks
-7%synergy
Infernal Grasp
12%inclusion6 decks52 decks
-14%synergy
Corrupted Conviction
12%inclusion6 decks52 decks
-1%synergy
Hagra Mauling
10%inclusion5 decks52 decks
5%synergy
Entomb
10%inclusion5 decks52 decks
-3%synergy
Supernatural Stamina
10%inclusion5 decks52 decks
2%synergy
Bitter Triumph
10%inclusion5 decks52 decks
-0%synergy
Darkness
10%inclusion5 decks52 decks
-1%synergy
Lethal Scheme
10%inclusion5 decks52 decks
7%synergy
Go for the Throat
7.7%inclusion4 decks52 decks
-15%synergy
Fake Your Own Death
7.7%inclusion4 decks52 decks
-0%synergy
Dismember
7.7%inclusion4 decks52 decks
-3%synergy
Hero's Downfall
5.8%inclusion3 decks52 decks
-1%synergy
Rise of the Dread Marn
5.8%inclusion3 decks52 decks
4%synergy
Sheoldred's Edict
5.8%inclusion3 decks52 decks
-9%synergy
Price of Fame
5.8%inclusion3 decks52 decks
5%synergy
Doom Blade
5.8%inclusion3 decks52 decks
-1%synergy
Drag to the Underworld
5.8%inclusion3 decks52 decks
4%synergy
Murder
5.8%inclusion3 decks52 decks
-4%synergy
Baleful Mastery
5.8%inclusion3 decks52 decks
-2%synergy
Sorceries
Victimize
40%inclusion21 decks52 decks
13%synergy
Sign in Blood
40%inclusion21 decks52 decks
6%synergy
Plague of Vermin
35%inclusion18 decks52 decks
32%synergy
Exsanguinate
31%inclusion16 decks52 decks
6%synergy
Diabolic Intent
27%inclusion14 decks52 decks
12%synergy
Army of the Damned
27%inclusion14 decks52 decks
22%synergy
Mutilate
21%inclusion11 decks52 decks
6%synergy
Night's Whisper
21%inclusion11 decks52 decks
-4%synergy
Torment of Hailfire
17%inclusion9 decks52 decks
3%synergy
Insatiable Avarice
17%inclusion9 decks52 decks
7%synergy
Damnation
17%inclusion9 decks52 decks
-3%synergy
Decorum Dissertation
16%inclusion5 decks32 decks
10%synergy
Coiling Rebirth
15%inclusion8 decks52 decks
14%synergy
Bubbling Muck
15%inclusion8 decks52 decks
-0%synergy
Agadeem's Awakening
15%inclusion8 decks52 decks
8%synergy
Blasphemous Edict
15%inclusion8 decks52 decks
-0%synergy
Dread Return
13%inclusion7 decks52 decks
2%synergy
Rise of the Dark Realms
12%inclusion6 decks52 decks
-2%synergy
Unearth
10%inclusion5 decks52 decks
1%synergy
Read the Bones
10%inclusion5 decks52 decks
-6%synergy
Living Death
10%inclusion5 decks52 decks
-1%synergy
Grim Tutor
10%inclusion5 decks52 decks
-2%synergy
Pox Plague
9.4%inclusion3 decks32 decks
4%synergy
Lively Dirge
7.7%inclusion4 decks52 decks
4%synergy
Diabolic Tutor
7.7%inclusion4 decks52 decks
-6%synergy
Scheming Symmetry
7.7%inclusion4 decks52 decks
3%synergy
Utility Artifacts
Skullclamp
42%inclusion22 decks52 decks
20%synergy
Ashnod's Altar
35%inclusion18 decks52 decks
15%synergy
Expedition Map
27%inclusion14 decks52 decks
16%synergy
Phyrexian Altar
23%inclusion12 decks52 decks
9%synergy
The Darkness Crystal
22%inclusion11 decks50 decks
2%synergy
Swiftfoot Boots
19%inclusion10 decks52 decks
-12%synergy
Lightning Greaves
19%inclusion10 decks52 decks
-15%synergy
Wayfarer's Bauble
13%inclusion7 decks52 decks
-1%synergy
Panharmonicon
12%inclusion6 decks52 decks
10%synergy
Desecrated Tomb
7.7%inclusion4 decks52 decks
6%synergy
Vat of Rebirth
7.7%inclusion4 decks52 decks
4%synergy
Lashwrithe
5.8%inclusion3 decks52 decks
2%synergy
Sting, the Glinting Dagger
5.8%inclusion3 decks52 decks
4%synergy
Enchantments
Dreadhorde Invasion
42%inclusion22 decks52 decks
34%synergy
The Meathook Massacre
42%inclusion22 decks52 decks
25%synergy
Bastion of Remembrance
38%inclusion20 decks52 decks
21%synergy
Grave Pact
33%inclusion17 decks52 decks
13%synergy
Dark Prophecy
33%inclusion17 decks52 decks
29%synergy
Black Market Connections
27%inclusion14 decks52 decks
2%synergy
Phyrexian Arena
25%inclusion13 decks52 decks
-14%synergy
Black Market
23%inclusion12 decks52 decks
3%synergy
Chthonian Nightmare
23%inclusion12 decks52 decks
19%synergy
Case of the Stashed Skeleton
21%inclusion11 decks52 decks
19%synergy
Dictate of Erebos
17%inclusion9 decks52 decks
6%synergy
Funeral Room // Awakening Hall
15%inclusion8 decks52 decks
11%synergy
Animate Dead
15%inclusion8 decks52 decks
-2%synergy
Oubliette
13%inclusion7 decks52 decks
11%synergy
Ripples of Undeath
12%inclusion6 decks52 decks
5%synergy
Attrition
10%inclusion5 decks52 decks
7%synergy
Phyrexian Reclamation
7.7%inclusion4 decks52 decks
-2%synergy
Sanguine Bond
7.7%inclusion4 decks52 decks
-4%synergy
Bloodchief Ascension
7.7%inclusion4 decks52 decks
-1%synergy
Oversold Cemetery
7.7%inclusion4 decks52 decks
2%synergy
Tortured Existence
7.7%inclusion4 decks52 decks
4%synergy
Virtue of Persistence
7.7%inclusion4 decks52 decks
3%synergy
Ghoulish Procession
5.8%inclusion3 decks52 decks
3%synergy
Vampiric Rites
5.8%inclusion3 decks52 decks
-0%synergy
Meathook Massacre II
5.8%inclusion3 decks52 decks
-0%synergy
Exquisite Blood
5.8%inclusion3 decks52 decks
-7%synergy
Underworld Dreams
5.8%inclusion3 decks52 decks
0%synergy
Rite of Belzenlok
5.8%inclusion3 decks52 decks
5%synergy
Kaya's Ghostform
5.8%inclusion3 decks52 decks
-4%synergy
Blight Mound
5.8%inclusion3 decks52 decks
3%synergy
Planeswalkers
Liliana, Dreadhorde General
35%inclusion18 decks52 decks
21%synergy
Lolth, Spider Queen
12%inclusion6 decks52 decks
10%synergy
Tevesh Szat, Doom of Fools
7.7%inclusion4 decks52 decks
5%synergy
Liliana, Death's Majesty
5.8%inclusion3 decks52 decks
2%synergy
Liliana of the Dark Realms
5.8%inclusion3 decks52 decks
-8%synergy
Utility Lands
Cabal Coffers
71%inclusion37 decks52 decks
16%synergy
Bojuka Bog
65%inclusion34 decks52 decks
18%synergy
Witch's Cottage
52%inclusion27 decks52 decks
27%synergy
Cabal Stronghold
44%inclusion23 decks52 decks
10%synergy
Castle Locthwain
40%inclusion21 decks52 decks
24%synergy
Nykthos, Shrine to Nyx
38%inclusion20 decks52 decks
9%synergy
Phyrexian Tower
35%inclusion18 decks52 decks
8%synergy
Urborg, Tomb of Yawgmoth
33%inclusion17 decks52 decks
-5%synergy
Mortuary Mire
19%inclusion10 decks52 decks
6%synergy
Crypt of Agadeem
17%inclusion9 decks52 decks
6%synergy
Spymaster's Vault
17%inclusion9 decks52 decks
8%synergy
Takenuma, Abandoned Mire
17%inclusion9 decks52 decks
2%synergy
Barren Moor
15%inclusion8 decks52 decks
6%synergy
War Room
15%inclusion8 decks52 decks
-1%synergy
High Market
15%inclusion8 decks52 decks
7%synergy
Westvale Abbey
13%inclusion7 decks52 decks
7%synergy
Barad-dûr
13%inclusion7 decks52 decks
10%synergy
Reliquary Tower
13%inclusion7 decks52 decks
-16%synergy
Susur Secundi, Void Altar
11%inclusion5 decks46 decks
4%synergy
Memorial to Folly
10%inclusion5 decks52 decks
7%synergy
Thespian's Stage
10%inclusion5 decks52 decks
5%synergy
Midgar, City of Mako
8.2%inclusion4 decks49 decks
-2%synergy
Tomb Fortress
7.7%inclusion4 decks52 decks
4%synergy
Terrain Generator
7.7%inclusion4 decks52 decks
6%synergy
Leechridden Swamp
7.7%inclusion4 decks52 decks
5%synergy
Blast Zone
5.8%inclusion3 decks52 decks
4%synergy
Temple of the False God
5.8%inclusion3 decks52 decks
-2%synergy
Mana Artifacts
Sol Ring
63%inclusion33 decks52 decks
-22%synergy
Arcane Signet
58%inclusion30 decks52 decks
-4%synergy
Crowded Crypt
25%inclusion13 decks52 decks
20%synergy
The Soul Stone
22%inclusion10 decks46 decks
6%synergy
Charcoal Diamond
21%inclusion11 decks52 decks
-0%synergy
Throne of Eldraine
13%inclusion7 decks52 decks
5%synergy
Nyx Lotus
12%inclusion6 decks52 decks
6%synergy
Fellwar Stone
10%inclusion5 decks52 decks
-4%synergy
Thought Vessel
10%inclusion5 decks52 decks
-15%synergy
Gauntlet of Power
7.7%inclusion4 decks52 decks
5%synergy
Caged Sun
5.8%inclusion3 decks52 decks
-4%synergy
Heraldic Banner
5.8%inclusion3 decks52 decks
1%synergy
Lands
Swamp
94%inclusion49 decks52 decks
-1%synergy
Malakir Rebirth
48%inclusion25 decks52 decks
24%synergy
Fell the Profane
37%inclusion19 decks52 decks
17%synergy
Boggart Trawler
23%inclusion12 decks52 decks
14%synergy
Urza's Cave
19%inclusion10 decks52 decks
11%synergy
Myriad Landscape
15%inclusion8 decks52 decks
-9%synergy
Agadeem's Awakening
15%inclusion8 decks52 decks
8%synergy
Hagra Mauling
10%inclusion5 decks52 decks
5%synergy
Snow-Covered Swamp
10%inclusion5 decks52 decks
3%synergy
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