Ayara, First of Locthwain (Commander) - Upgraded Lifedrain

Ayara, First of Locthwain
Rank #378
51decks
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Josh Nelson
Jul 16, 2026
Josh Nelson
Ten Combos for Your Next Monocolor Commander Decks
Ten mono-color Commander combos, two per color, from the Pickles lock to Squirrel Nest + Earthcraft, that you can drop into your next builds.
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Top Cards
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Creatures
Instants
Sorceries
Utility Artifacts
Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
Back to Top
Rage into the Valley
7.1%inclusion1 decks14 decks
7%synergy
The Sackville-Bagginses
6.3%inclusion1 decks16 decks
5%synergy
High Synergy Cards
Ophiomancer
76%inclusion39 decks51 decks
59%synergy
Jadar, Ghoulcaller of Nephalia
69%inclusion35 decks51 decks
58%synergy
Abhorrent Overlord
57%inclusion29 decks51 decks
53%synergy
Reassembling Skeleton
61%inclusion31 decks51 decks
43%synergy
Bitterblossom
55%inclusion28 decks51 decks
42%synergy
Gray Merchant of Asphodel
90%inclusion46 decks51 decks
40%synergy
Zulaport Cutthroat
63%inclusion32 decks51 decks
40%synergy
Viscera Seer
57%inclusion29 decks51 decks
40%synergy
Pitiless Plunderer
57%inclusion29 decks51 decks
37%synergy
Starscape Cleric
39%inclusion20 decks51 decks
36%synergy
Top Cards
Dark Ritual
76%inclusion39 decks51 decks
9%synergy
Jet Medallion
75%inclusion38 decks51 decks
12%synergy
Crypt Ghast
73%inclusion37 decks51 decks
26%synergy
Toxic Deluge
61%inclusion31 decks51 decks
24%synergy
Feed the Swarm
55%inclusion28 decks51 decks
5%synergy
Braids, Arisen Nightmare
53%inclusion27 decks51 decks
33%synergy
Syr Konrad, the Grim
51%inclusion26 decks51 decks
31%synergy
Blood Artist
51%inclusion26 decks51 decks
19%synergy
Bontu's Monument
49%inclusion25 decks51 decks
21%synergy
Reanimate
47%inclusion24 decks51 decks
6%synergy
Game Changers
Bolas's Citadel
51%inclusion26 decks51 decks
23%synergy
Demonic Tutor
22%inclusion11 decks51 decks
-6%synergy
Orcish Bowmasters
16%inclusion8 decks51 decks
3%synergy
Necropotence
14%inclusion7 decks51 decks
-1%synergy
Braids, Cabal Minion
7.8%inclusion4 decks51 decks
4%synergy
Vampiric Tutor
7.8%inclusion4 decks51 decks
-13%synergy
Creatures
Bitterbloom Bearer
42%inclusion18 decks43 decks
35%synergy
Gravecrawler
41%inclusion21 decks51 decks
26%synergy
Morbid Opportunist
41%inclusion21 decks51 decks
17%synergy
Endrek Sahr, Master Breeder
41%inclusion21 decks51 decks
35%synergy
Marauding Blight-Priest
37%inclusion19 decks51 decks
30%synergy
Warren Soultrader
37%inclusion19 decks51 decks
23%synergy
Bloodletter of Aclazotz
37%inclusion19 decks51 decks
27%synergy
Bloodghast
37%inclusion19 decks51 decks
25%synergy
Massacre Wurm
35%inclusion18 decks51 decks
18%synergy
Grim Servant
33%inclusion17 decks51 decks
29%synergy
Grave Titan
33%inclusion17 decks51 decks
27%synergy
Vito, Thorn of the Dusk Rose
31%inclusion16 decks51 decks
21%synergy
K'rrik, Son of Yawgmoth
31%inclusion16 decks51 decks
12%synergy
Chittering Witch
29%inclusion15 decks51 decks
25%synergy
Marionette Apprentice
29%inclusion15 decks51 decks
19%synergy
Scheming Silvertongue
29%inclusion9 decks31 decks
23%synergy
Sengir Autocrat
27%inclusion14 decks51 decks
26%synergy
Nine-Lives Familiar
27%inclusion14 decks51 decks
19%synergy
Mirkwood Bats
25%inclusion13 decks51 decks
17%synergy
Lord Skitter, Sewer King
25%inclusion13 decks51 decks
17%synergy
Accursed Marauder
25%inclusion13 decks51 decks
4%synergy
Witch of the Moors
25%inclusion13 decks51 decks
22%synergy
Dark Confidant
25%inclusion13 decks51 decks
18%synergy
Umbral Collar Zealot
24%inclusion11 decks45 decks
16%synergy
Boggart Trawler
24%inclusion12 decks51 decks
14%synergy
Carrion Feeder
24%inclusion12 decks51 decks
12%synergy
Ogre Slumlord
24%inclusion12 decks51 decks
14%synergy
Darkstar Augur
24%inclusion12 decks51 decks
22%synergy
Nether Traitor
24%inclusion12 decks51 decks
15%synergy
Yawgmoth, Thran Physician
24%inclusion12 decks51 decks
14%synergy
Moseo, Vein's New Dean
23%inclusion7 decks31 decks
19%synergy
Priest of Forgotten Gods
22%inclusion11 decks51 decks
13%synergy
Enduring Tenacity
22%inclusion11 decks51 decks
13%synergy
Ravenous Chupacabra
22%inclusion11 decks51 decks
17%synergy
Midnight Reaper
22%inclusion11 decks51 decks
13%synergy
Hoarding Broodlord
20%inclusion10 decks51 decks
15%synergy
Vindictive Vampire
20%inclusion10 decks51 decks
17%synergy
Timeline Culler
18%inclusion8 decks45 decks
13%synergy
Grim Haruspex
18%inclusion9 decks51 decks
9%synergy
Grave Researcher
18%inclusion6 decks34 decks
10%synergy
Ghoulcaller Gisa
18%inclusion9 decks51 decks
13%synergy
Dauthi Voidwalker
18%inclusion9 decks51 decks
2%synergy
Great Unclean One
18%inclusion9 decks51 decks
16%synergy
Veinwitch Coven
18%inclusion9 decks51 decks
16%synergy
Woe Strider
16%inclusion8 decks51 decks
11%synergy
Dread Presence
16%inclusion8 decks51 decks
2%synergy
Sephiroth, Fabled SOLDIER
14%inclusion7 decks49 decks
9%synergy
Plaguecrafter
14%inclusion7 decks51 decks
-6%synergy
Erebos, God of the Dead
14%inclusion7 decks51 decks
9%synergy
Murderous Rider
14%inclusion7 decks51 decks
8%synergy
Instants
Malakir Rebirth
47%inclusion24 decks51 decks
23%synergy
Defile
41%inclusion21 decks51 decks
6%synergy
Withering Torment
41%inclusion21 decks51 decks
10%synergy
Tragic Slip
37%inclusion19 decks51 decks
18%synergy
Fell the Profane
35%inclusion18 decks51 decks
16%synergy
Village Rites
35%inclusion18 decks51 decks
10%synergy
Szat's Will
33%inclusion17 decks51 decks
31%synergy
Deadly Dispute
27%inclusion14 decks51 decks
0%synergy
Consuming Corruption
24%inclusion12 decks51 decks
8%synergy
Saw in Half
24%inclusion12 decks51 decks
15%synergy
Culling the Weak
22%inclusion11 decks51 decks
4%synergy
Force of Despair
20%inclusion10 decks51 decks
12%synergy
Imp's Mischief
20%inclusion10 decks51 decks
-6%synergy
Snuff Out
20%inclusion10 decks51 decks
6%synergy
Flare of Malice
20%inclusion10 decks51 decks
6%synergy
Undying Malice
18%inclusion9 decks51 decks
7%synergy
Not Dead After All
16%inclusion8 decks51 decks
4%synergy
Soul Shatter
16%inclusion8 decks51 decks
4%synergy
Plumb the Forbidden
16%inclusion8 decks51 decks
11%synergy
Feign Death
16%inclusion8 decks51 decks
7%synergy
Archenemy's Charm
16%inclusion7 decks45 decks
7%synergy
Deadly Rollick
14%inclusion7 decks51 decks
-12%synergy
Entomb
12%inclusion6 decks51 decks
-1%synergy
Cabal Ritual
12%inclusion6 decks51 decks
-7%synergy
Infernal Grasp
12%inclusion6 decks51 decks
-13%synergy
Corrupted Conviction
12%inclusion6 decks51 decks
-1%synergy
Bitter Triumph
10%inclusion5 decks51 decks
-0%synergy
Darkness
10%inclusion5 decks51 decks
-1%synergy
Lethal Scheme
10%inclusion5 decks51 decks
7%synergy
Hagra Mauling
7.8%inclusion4 decks51 decks
4%synergy
Rise of the Dread Marn
7.8%inclusion4 decks51 decks
6%synergy
Go for the Throat
7.8%inclusion4 decks51 decks
-15%synergy
Supernatural Stamina
7.8%inclusion4 decks51 decks
0%synergy
Murder
7.8%inclusion4 decks51 decks
-2%synergy
Dismember
7.8%inclusion4 decks51 decks
-3%synergy
Foolish Fate
6.5%inclusion2 decks31 decks
6%synergy
Sacrifice
5.9%inclusion3 decks51 decks
1%synergy
Sheoldred's Edict
5.9%inclusion3 decks51 decks
-9%synergy
Doom Blade
5.9%inclusion3 decks51 decks
-1%synergy
Altar's Reap
5.9%inclusion3 decks51 decks
4%synergy
Fake Your Own Death
5.9%inclusion3 decks51 decks
-2%synergy
Sorceries
Sign in Blood
45%inclusion23 decks51 decks
10%synergy
Victimize
39%inclusion20 decks51 decks
12%synergy
Plague of Vermin
37%inclusion19 decks51 decks
35%synergy
Exsanguinate
31%inclusion16 decks51 decks
7%synergy
Army of the Damned
27%inclusion14 decks51 decks
23%synergy
Diabolic Intent
25%inclusion13 decks51 decks
10%synergy
Mutilate
22%inclusion11 decks51 decks
6%synergy
Damnation
22%inclusion11 decks51 decks
2%synergy
Night's Whisper
20%inclusion10 decks51 decks
-6%synergy
Torment of Hailfire
18%inclusion9 decks51 decks
3%synergy
Insatiable Avarice
18%inclusion9 decks51 decks
7%synergy
Decorum Dissertation
16%inclusion5 decks31 decks
10%synergy
Coiling Rebirth
16%inclusion8 decks51 decks
14%synergy
Blasphemous Edict
14%inclusion7 decks51 decks
-2%synergy
Dread Return
12%inclusion6 decks51 decks
-0%synergy
Bubbling Muck
12%inclusion6 decks51 decks
-4%synergy
Agadeem's Awakening
12%inclusion6 decks51 decks
4%synergy
Rise of the Dark Realms
12%inclusion6 decks51 decks
-2%synergy
Grim Tutor
12%inclusion6 decks51 decks
0%synergy
Read the Bones
10%inclusion5 decks51 decks
-6%synergy
Pox Plague
10%inclusion3 decks31 decks
4%synergy
Diabolic Tutor
7.8%inclusion4 decks51 decks
-6%synergy
Unearth
7.8%inclusion4 decks51 decks
-1%synergy
Scheming Symmetry
7.8%inclusion4 decks51 decks
3%synergy
Living Death
7.8%inclusion4 decks51 decks
-2%synergy
Syphon Mind
7.8%inclusion4 decks51 decks
-4%synergy
Lively Dirge
5.9%inclusion3 decks51 decks
2%synergy
Persist
5.9%inclusion3 decks51 decks
2%synergy
Buried Alive
5.9%inclusion3 decks51 decks
-7%synergy
Deadly Tempest
5.9%inclusion3 decks51 decks
4%synergy
Splinter's Technique
5.1%inclusion2 decks39 decks
3%synergy
Utility Artifacts
Skullclamp
43%inclusion22 decks51 decks
21%synergy
Ashnod's Altar
35%inclusion18 decks51 decks
15%synergy
Expedition Map
29%inclusion15 decks51 decks
18%synergy
Phyrexian Altar
27%inclusion14 decks51 decks
14%synergy
The Darkness Crystal
24%inclusion12 decks49 decks
4%synergy
Swiftfoot Boots
20%inclusion10 decks51 decks
-12%synergy
Lightning Greaves
20%inclusion10 decks51 decks
-14%synergy
Wayfarer's Bauble
14%inclusion7 decks51 decks
-1%synergy
Panharmonicon
10%inclusion5 decks51 decks
8%synergy
Desecrated Tomb
7.8%inclusion4 decks51 decks
6%synergy
Vat of Rebirth
7.8%inclusion4 decks51 decks
5%synergy
Sting, the Glinting Dagger
5.9%inclusion3 decks51 decks
4%synergy
Enchantments
Dreadhorde Invasion
43%inclusion22 decks51 decks
35%synergy
Bastion of Remembrance
43%inclusion22 decks51 decks
26%synergy
The Meathook Massacre
39%inclusion20 decks51 decks
22%synergy
Grave Pact
31%inclusion16 decks51 decks
12%synergy
Dark Prophecy
29%inclusion15 decks51 decks
26%synergy
Phyrexian Arena
27%inclusion14 decks51 decks
-12%synergy
Black Market
25%inclusion13 decks51 decks
5%synergy
Black Market Connections
25%inclusion13 decks51 decks
0%synergy
Case of the Stashed Skeleton
22%inclusion11 decks51 decks
20%synergy
Chthonian Nightmare
22%inclusion11 decks51 decks
18%synergy
Dictate of Erebos
16%inclusion8 decks51 decks
5%synergy
Funeral Room // Awakening Hall
16%inclusion8 decks51 decks
11%synergy
Animate Dead
16%inclusion8 decks51 decks
-2%synergy
Ripples of Undeath
12%inclusion6 decks51 decks
6%synergy
Oubliette
12%inclusion6 decks51 decks
9%synergy
Sanguine Bond
10%inclusion5 decks51 decks
-2%synergy
Bloodchief Ascension
10%inclusion5 decks51 decks
1%synergy
Vampiric Rites
7.8%inclusion4 decks51 decks
2%synergy
Exquisite Blood
7.8%inclusion4 decks51 decks
-5%synergy
Attrition
7.8%inclusion4 decks51 decks
5%synergy
Virtue of Persistence
7.8%inclusion4 decks51 decks
3%synergy
Sothera, the Supervoid
6.5%inclusion3 decks46 decks
4%synergy
Ghoulish Procession
5.9%inclusion3 decks51 decks
3%synergy
Phyrexian Reclamation
5.9%inclusion3 decks51 decks
-4%synergy
Meathook Massacre II
5.9%inclusion3 decks51 decks
-0%synergy
Underworld Dreams
5.9%inclusion3 decks51 decks
0%synergy
No Mercy
5.9%inclusion3 decks51 decks
-2%synergy
Blight Mound
5.9%inclusion3 decks51 decks
3%synergy
Oversold Cemetery
5.9%inclusion3 decks51 decks
1%synergy
Tortured Existence
5.9%inclusion3 decks51 decks
2%synergy
Planeswalkers
Liliana, Dreadhorde General
35%inclusion18 decks51 decks
22%synergy
Lolth, Spider Queen
12%inclusion6 decks51 decks
10%synergy
Tevesh Szat, Doom of Fools
5.9%inclusion3 decks51 decks
3%synergy
Liliana, Death's Majesty
5.9%inclusion3 decks51 decks
2%synergy
Liliana of the Dark Realms
5.9%inclusion3 decks51 decks
-8%synergy
Utility Lands
Cabal Coffers
73%inclusion37 decks51 decks
18%synergy
Bojuka Bog
65%inclusion33 decks51 decks
18%synergy
Witch's Cottage
51%inclusion26 decks51 decks
27%synergy
Cabal Stronghold
47%inclusion24 decks51 decks
13%synergy
Nykthos, Shrine to Nyx
41%inclusion21 decks51 decks
11%synergy
Castle Locthwain
41%inclusion21 decks51 decks
25%synergy
Phyrexian Tower
37%inclusion19 decks51 decks
11%synergy
Urborg, Tomb of Yawgmoth
35%inclusion18 decks51 decks
-2%synergy
Mortuary Mire
18%inclusion9 decks51 decks
5%synergy
Spymaster's Vault
18%inclusion9 decks51 decks
8%synergy
Takenuma, Abandoned Mire
18%inclusion9 decks51 decks
2%synergy
Barren Moor
16%inclusion8 decks51 decks
6%synergy
Crypt of Agadeem
16%inclusion8 decks51 decks
4%synergy
War Room
16%inclusion8 decks51 decks
-0%synergy
High Market
16%inclusion8 decks51 decks
8%synergy
Reliquary Tower
16%inclusion8 decks51 decks
-14%synergy
Westvale Abbey
14%inclusion7 decks51 decks
7%synergy
Barad-dûr
14%inclusion7 decks51 decks
10%synergy
Susur Secundi, Void Altar
13%inclusion6 decks45 decks
6%synergy
Memorial to Folly
10%inclusion5 decks51 decks
7%synergy
Thespian's Stage
10%inclusion5 decks51 decks
5%synergy
Leechridden Swamp
10%inclusion5 decks51 decks
7%synergy
Midgar, City of Mako
8.3%inclusion4 decks48 decks
-2%synergy
Tomb Fortress
7.8%inclusion4 decks51 decks
4%synergy
Terrain Generator
7.8%inclusion4 decks51 decks
6%synergy
Blast Zone
5.9%inclusion3 decks51 decks
4%synergy
Temple of the False God
5.9%inclusion3 decks51 decks
-2%synergy
Mana Artifacts
Sol Ring
67%inclusion34 decks51 decks
-19%synergy
Arcane Signet
59%inclusion30 decks51 decks
-3%synergy
Crowded Crypt
25%inclusion13 decks51 decks
21%synergy
The Soul Stone
20%inclusion9 decks45 decks
4%synergy
Charcoal Diamond
20%inclusion10 decks51 decks
-2%synergy
Nyx Lotus
14%inclusion7 decks51 decks
8%synergy
Throne of Eldraine
12%inclusion6 decks51 decks
3%synergy
Thought Vessel
12%inclusion6 decks51 decks
-13%synergy
Fellwar Stone
10%inclusion5 decks51 decks
-4%synergy
Caged Sun
7.8%inclusion4 decks51 decks
-2%synergy
Gauntlet of Power
7.8%inclusion4 decks51 decks
5%synergy
Heraldic Banner
5.9%inclusion3 decks51 decks
1%synergy
Lands
Swamp
94%inclusion48 decks51 decks
-1%synergy
Malakir Rebirth
47%inclusion24 decks51 decks
23%synergy
Fell the Profane
35%inclusion18 decks51 decks
16%synergy
Boggart Trawler
24%inclusion12 decks51 decks
14%synergy
Urza's Cave
22%inclusion11 decks51 decks
13%synergy
Myriad Landscape
16%inclusion8 decks51 decks
-9%synergy
Agadeem's Awakening
12%inclusion6 decks51 decks
4%synergy
Hagra Mauling
7.8%inclusion4 decks51 decks
4%synergy
Snow-Covered Swamp
7.8%inclusion4 decks51 decks
1%synergy
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