Ayara, First of Locthwain (Commander) - Optimized Lifedrain

Ayara, First of Locthwain
Rank #379
22decks
As CommanderAs CardAverage DeckDecks
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Josh Nelson
Jul 16, 2026
Josh Nelson
Ten Combos for Your Next Monocolor Commander Decks
Ten mono-color Commander combos, two per color, from the Pickles lock to Squirrel Nest + Earthcraft, that you can drop into your next builds.
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Sorceries
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Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
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Ophiomancer
86%inclusion19 decks22 decks
69%synergy
Jadar, Ghoulcaller of Nephalia
73%inclusion16 decks22 decks
62%synergy
Bitterblossom
73%inclusion16 decks22 decks
60%synergy
Liliana, Dreadhorde General
59%inclusion13 decks22 decks
46%synergy
Toxic Deluge
82%inclusion18 decks22 decks
45%synergy
Zulaport Cutthroat
68%inclusion15 decks22 decks
45%synergy
Plague of Vermin
45%inclusion10 decks22 decks
43%synergy
Nykthos, Shrine to Nyx
73%inclusion16 decks22 decks
43%synergy
Blood Artist
73%inclusion16 decks22 decks
41%synergy
Gray Merchant of Asphodel
91%inclusion20 decks22 decks
40%synergy
Top Cards
Crypt Ghast
86%inclusion19 decks22 decks
39%synergy
Jet Medallion
86%inclusion19 decks22 decks
24%synergy
Dark Ritual
77%inclusion17 decks22 decks
10%synergy
Reanimate
64%inclusion14 decks22 decks
23%synergy
Skullclamp
59%inclusion13 decks22 decks
37%synergy
Pitiless Plunderer
59%inclusion13 decks22 decks
39%synergy
Victimize
55%inclusion12 decks22 decks
27%synergy
Gravecrawler
50%inclusion11 decks22 decks
35%synergy
Feed the Swarm
50%inclusion11 decks22 decks
-0%synergy
Phyrexian Altar
50%inclusion11 decks22 decks
36%synergy
Game Changers
Bolas's Citadel
86%inclusion19 decks22 decks
58%synergy
Demonic Tutor
45%inclusion10 decks22 decks
18%synergy
Necropotence
45%inclusion10 decks22 decks
31%synergy
Vampiric Tutor
45%inclusion10 decks22 decks
25%synergy
The One Ring
41%inclusion9 decks22 decks
32%synergy
Orcish Bowmasters
41%inclusion9 decks22 decks
28%synergy
Opposition Agent
18%inclusion4 decks22 decks
9%synergy
Imperial Seal
9.1%inclusion2 decks22 decks
2%synergy
Ancient Tomb
9.1%inclusion2 decks22 decks
-3%synergy
Tergrid, God of Fright
9.1%inclusion2 decks22 decks
2%synergy
Creatures
Braids, Arisen Nightmare
50%inclusion11 decks22 decks
30%synergy
Viscera Seer
50%inclusion11 decks22 decks
33%synergy
Endrek Sahr, Master Breeder
45%inclusion10 decks22 decks
39%synergy
Reassembling Skeleton
45%inclusion10 decks22 decks
28%synergy
Warren Soultrader
45%inclusion10 decks22 decks
32%synergy
Abhorrent Overlord
41%inclusion9 decks22 decks
37%synergy
Syr Konrad, the Grim
41%inclusion9 decks22 decks
21%synergy
Vito, Thorn of the Dusk Rose
41%inclusion9 decks22 decks
30%synergy
Carrion Feeder
41%inclusion9 decks22 decks
29%synergy
Yawgmoth, Thran Physician
41%inclusion9 decks22 decks
31%synergy
Lord Skitter, Sewer King
41%inclusion9 decks22 decks
33%synergy
Sheoldred, the Apocalypse
36%inclusion8 decks22 decks
22%synergy
Bloodghast
36%inclusion8 decks22 decks
24%synergy
Bitterbloom Bearer
35%inclusion6 decks17 decks
29%synergy
Mirkwood Bats
32%inclusion7 decks22 decks
23%synergy
Murderous Rider
32%inclusion7 decks22 decks
26%synergy
Priest of Forgotten Gods
32%inclusion7 decks22 decks
23%synergy
Massacre Wurm
32%inclusion7 decks22 decks
15%synergy
Grave Titan
32%inclusion7 decks22 decks
25%synergy
Bloodthirsty Conqueror
32%inclusion7 decks22 decks
23%synergy
Nine-Lives Familiar
27%inclusion6 decks22 decks
19%synergy
Boggart Trawler
27%inclusion6 decks22 decks
18%synergy
Witch of the Moors
27%inclusion6 decks22 decks
23%synergy
Marauding Blight-Priest
27%inclusion6 decks22 decks
20%synergy
Midnight Reaper
27%inclusion6 decks22 decks
19%synergy
Sengir Autocrat
23%inclusion5 decks22 decks
21%synergy
Ghoulcaller Gisa
23%inclusion5 decks22 decks
18%synergy
Dread Presence
23%inclusion5 decks22 decks
9%synergy
Morbid Opportunist
23%inclusion5 decks22 decks
-1%synergy
Starscape Cleric
23%inclusion5 decks22 decks
19%synergy
Chittering Witch
23%inclusion5 decks22 decks
18%synergy
Sheoldred, Whispering One
23%inclusion5 decks22 decks
11%synergy
Great Unclean One
23%inclusion5 decks22 decks
21%synergy
Sephiroth, Fabled SOLDIER
19%inclusion4 decks21 decks
14%synergy
Dark Confidant
18%inclusion4 decks22 decks
10%synergy
Plaguecrafter
18%inclusion4 decks22 decks
-2%synergy
Phyrexian Obliterator
18%inclusion4 decks22 decks
7%synergy
Bloodletter of Aclazotz
18%inclusion4 decks22 decks
8%synergy
Mikaeus, the Unhallowed
18%inclusion4 decks22 decks
11%synergy
Massacre Girl
18%inclusion4 decks22 decks
11%synergy
Marionette Apprentice
18%inclusion4 decks22 decks
7%synergy
Enduring Tenacity
18%inclusion4 decks22 decks
10%synergy
Veinwitch Coven
18%inclusion4 decks22 decks
16%synergy
Darkstar Augur
14%inclusion3 decks22 decks
12%synergy
Ogre Slumlord
14%inclusion3 decks22 decks
4%synergy
Erebos, God of the Dead
14%inclusion3 decks22 decks
9%synergy
Nether Traitor
14%inclusion3 decks22 decks
5%synergy
Grim Haruspex
14%inclusion3 decks22 decks
5%synergy
Ravenous Chupacabra
14%inclusion3 decks22 decks
9%synergy
Vilis, Broker of Blood
14%inclusion3 decks22 decks
1%synergy
Instants
Withering Torment
41%inclusion9 decks22 decks
10%synergy
Deadly Rollick
36%inclusion8 decks22 decks
11%synergy
Malakir Rebirth
36%inclusion8 decks22 decks
13%synergy
Imp's Mischief
32%inclusion7 decks22 decks
7%synergy
Snuff Out
32%inclusion7 decks22 decks
18%synergy
Tragic Slip
32%inclusion7 decks22 decks
13%synergy
Fell the Profane
27%inclusion6 decks22 decks
8%synergy
Defile
27%inclusion6 decks22 decks
-8%synergy
Village Rites
23%inclusion5 decks22 decks
-3%synergy
Culling the Weak
23%inclusion5 decks22 decks
5%synergy
Bitter Triumph
23%inclusion5 decks22 decks
13%synergy
Saw in Half
23%inclusion5 decks22 decks
14%synergy
Go for the Throat
18%inclusion4 decks22 decks
-4%synergy
Baleful Mastery
18%inclusion4 decks22 decks
10%synergy
Force of Despair
14%inclusion3 decks22 decks
6%synergy
Heartless Act
14%inclusion3 decks22 decks
12%synergy
Consuming Corruption
14%inclusion3 decks22 decks
-2%synergy
Deadly Dispute
14%inclusion3 decks22 decks
-13%synergy
Flare of Malice
14%inclusion3 decks22 decks
0%synergy
Cabal Ritual
14%inclusion3 decks22 decks
-5%synergy
Infernal Grasp
14%inclusion3 decks22 decks
-12%synergy
Archenemy's Charm
10%inclusion2 decks20 decks
1%synergy
Rise of the Dread Marn
9.1%inclusion2 decks22 decks
7%synergy
Bile Blight
9.1%inclusion2 decks22 decks
8%synergy
Sheoldred's Edict
9.1%inclusion2 decks22 decks
-6%synergy
Entomb
9.1%inclusion2 decks22 decks
-3%synergy
Soul Shatter
9.1%inclusion2 decks22 decks
-3%synergy
Ad Nauseam
9.1%inclusion2 decks22 decks
6%synergy
Demonic Consultation
9.1%inclusion2 decks22 decks
8%synergy
Plumb the Forbidden
9.1%inclusion2 decks22 decks
5%synergy
Corrupted Conviction
9.1%inclusion2 decks22 decks
-3%synergy
Sudden Spoiling
9.1%inclusion2 decks22 decks
1%synergy
Szat's Will
9.1%inclusion2 decks22 decks
7%synergy
Dismember
9.1%inclusion2 decks22 decks
-1%synergy
Sorceries
Army of the Damned
41%inclusion9 decks22 decks
36%synergy
Diabolic Intent
36%inclusion8 decks22 decks
21%synergy
Insatiable Avarice
36%inclusion8 decks22 decks
25%synergy
Exsanguinate
32%inclusion7 decks22 decks
7%synergy
Damnation
32%inclusion7 decks22 decks
12%synergy
Mutilate
27%inclusion6 decks22 decks
11%synergy
Bubbling Muck
23%inclusion5 decks22 decks
7%synergy
Sign in Blood
23%inclusion5 decks22 decks
-12%synergy
Torment of Hailfire
18%inclusion4 decks22 decks
3%synergy
Agadeem's Awakening
18%inclusion4 decks22 decks
11%synergy
Blasphemous Edict
18%inclusion4 decks22 decks
2%synergy
Beseech the Mirror
18%inclusion4 decks22 decks
11%synergy
Beseech the Queen
18%inclusion4 decks22 decks
12%synergy
Persist
14%inclusion3 decks22 decks
10%synergy
Unearth
14%inclusion3 decks22 decks
5%synergy
Read the Bones
14%inclusion3 decks22 decks
-2%synergy
Night's Whisper
14%inclusion3 decks22 decks
-11%synergy
Buried Alive
14%inclusion3 decks22 decks
1%synergy
Lively Dirge
9.1%inclusion2 decks22 decks
5%synergy
Dread Return
9.1%inclusion2 decks22 decks
-3%synergy
Rise of the Dark Realms
9.1%inclusion2 decks22 decks
-4%synergy
Grim Tutor
9.1%inclusion2 decks22 decks
-2%synergy
Splinter's Technique
7.7%inclusion1 decks13 decks
6%synergy
Utility Artifacts
Bontu's Monument
45%inclusion10 decks22 decks
17%synergy
Ashnod's Altar
36%inclusion8 decks22 decks
17%synergy
Swiftfoot Boots
36%inclusion8 decks22 decks
5%synergy
Lightning Greaves
27%inclusion6 decks22 decks
-7%synergy
Whip of Erebos
18%inclusion4 decks22 decks
7%synergy
Wishclaw Talisman
14%inclusion3 decks22 decks
7%synergy
The Darkness Crystal
10%inclusion2 decks21 decks
-11%synergy
Wayfarer's Bauble
9.1%inclusion2 decks22 decks
-6%synergy
Panharmonicon
9.1%inclusion2 decks22 decks
8%synergy
Altar of Dementia
9.1%inclusion2 decks22 decks
4%synergy
Spawning Pit
9.1%inclusion2 decks22 decks
8%synergy
Enchantments
Phyrexian Arena
50%inclusion11 decks22 decks
11%synergy
The Meathook Massacre
41%inclusion9 decks22 decks
24%synergy
Grave Pact
41%inclusion9 decks22 decks
21%synergy
Exquisite Blood
41%inclusion9 decks22 decks
28%synergy
Dreadhorde Invasion
36%inclusion8 decks22 decks
28%synergy
Sanguine Bond
32%inclusion7 decks22 decks
20%synergy
Dictate of Erebos
32%inclusion7 decks22 decks
21%synergy
Animate Dead
32%inclusion7 decks22 decks
14%synergy
Bastion of Remembrance
23%inclusion5 decks22 decks
6%synergy
Black Market
18%inclusion4 decks22 decks
-2%synergy
Phyrexian Reclamation
18%inclusion4 decks22 decks
8%synergy
Meathook Massacre II
18%inclusion4 decks22 decks
12%synergy
Contamination
14%inclusion3 decks22 decks
10%synergy
Blight Mound
14%inclusion3 decks22 decks
11%synergy
Black Market Connections
14%inclusion3 decks22 decks
-11%synergy
Dark Prophecy
14%inclusion3 decks22 decks
10%synergy
Curse of the Restless Dead
9.1%inclusion2 decks22 decks
8%synergy
Greed
9.1%inclusion2 decks22 decks
3%synergy
Carnival of Souls
9.1%inclusion2 decks22 decks
8%synergy
Tombstone Stairwell
9.1%inclusion2 decks22 decks
8%synergy
Funeral Room // Awakening Hall
9.1%inclusion2 decks22 decks
5%synergy
Kaya's Ghostform
9.1%inclusion2 decks22 decks
-1%synergy
Planeswalkers
Tevesh Szat, Doom of Fools
23%inclusion5 decks22 decks
20%synergy
Lolth, Spider Queen
14%inclusion3 decks22 decks
12%synergy
Utility Lands
Cabal Coffers
91%inclusion20 decks22 decks
36%synergy
Urborg, Tomb of Yawgmoth
73%inclusion16 decks22 decks
35%synergy
Bojuka Bog
68%inclusion15 decks22 decks
21%synergy
Phyrexian Tower
59%inclusion13 decks22 decks
33%synergy
Witch's Cottage
50%inclusion11 decks22 decks
26%synergy
Castle Locthwain
50%inclusion11 decks22 decks
33%synergy
Cabal Stronghold
45%inclusion10 decks22 decks
11%synergy
Barad-dûr
27%inclusion6 decks22 decks
24%synergy
Takenuma, Abandoned Mire
27%inclusion6 decks22 decks
12%synergy
High Market
23%inclusion5 decks22 decks
15%synergy
Barren Moor
18%inclusion4 decks22 decks
9%synergy
War Room
18%inclusion4 decks22 decks
2%synergy
Ghost Quarter
14%inclusion3 decks22 decks
11%synergy
Crypt of Agadeem
14%inclusion3 decks22 decks
2%synergy
Deserted Temple
14%inclusion3 decks22 decks
9%synergy
Emergence Zone
9.1%inclusion2 decks22 decks
6%synergy
Fountainport
9.1%inclusion2 decks22 decks
8%synergy
Polluted Mire
9.1%inclusion2 decks22 decks
6%synergy
Reliquary Tower
9.1%inclusion2 decks22 decks
-21%synergy
Leechridden Swamp
9.1%inclusion2 decks22 decks
6%synergy
Susur Secundi, Void Altar
5.0%inclusion1 decks20 decks
-2%synergy
Eumidian Hatchery
5.0%inclusion1 decks20 decks
4%synergy
Mana Artifacts
Sol Ring
91%inclusion20 decks22 decks
5%synergy
Arcane Signet
64%inclusion14 decks22 decks
2%synergy
Charcoal Diamond
18%inclusion4 decks22 decks
-4%synergy
Throne of Eldraine
18%inclusion4 decks22 decks
9%synergy
Nyx Lotus
18%inclusion4 decks22 decks
12%synergy
Crowded Crypt
14%inclusion3 decks22 decks
9%synergy
Lotus Petal
14%inclusion3 decks22 decks
6%synergy
Mind Stone
14%inclusion3 decks22 decks
-14%synergy
Heraldic Banner
9.1%inclusion2 decks22 decks
4%synergy
Fellwar Stone
9.1%inclusion2 decks22 decks
-5%synergy
Thought Vessel
9.1%inclusion2 decks22 decks
-16%synergy
Springleaf Drum
9.1%inclusion2 decks22 decks
7%synergy
Mox Diamond
9.1%inclusion2 decks22 decks
5%synergy
The Soul Stone
5.3%inclusion1 decks19 decks
-10%synergy
Lands
Swamp
100%inclusion22 decks22 decks
5%synergy
Malakir Rebirth
36%inclusion8 decks22 decks
13%synergy
Myriad Landscape
32%inclusion7 decks22 decks
7%synergy
Fell the Profane
27%inclusion6 decks22 decks
8%synergy
Boggart Trawler
27%inclusion6 decks22 decks
18%synergy
Agadeem's Awakening
18%inclusion4 decks22 decks
11%synergy
Urza's Cave
9.1%inclusion2 decks22 decks
1%synergy
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