Skithiryx, the Blight Dragon (Commander) - Optimized Equipment

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Enchantments
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Utility Lands
Mana Artifacts
Lands
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Bitterbloom Bearer
25%inclusion1 decks4 decks
20%synergy
High Synergy Cards
Plague Stinger
83%inclusion5 decks6 decks
82%synergy
Nightmare Lash
83%inclusion5 decks6 decks
81%synergy
Commander's Plate
83%inclusion5 decks6 decks
78%synergy
Whispering Specter
67%inclusion4 decks6 decks
66%synergy
Howl from Beyond
67%inclusion4 decks6 decks
66%synergy
Inkmoth Nexus
67%inclusion4 decks6 decks
66%synergy
Cabal Ritual
83%inclusion5 decks6 decks
65%synergy
Phyresis Outbreak
67%inclusion4 decks6 decks
65%synergy
Rogue's Passage
83%inclusion5 decks6 decks
64%synergy
Blackblade Reforged
67%inclusion4 decks6 decks
64%synergy
Top Cards
Dark Ritual
100%inclusion6 decks6 decks
33%synergy
Feed the Swarm
100%inclusion6 decks6 decks
49%synergy
Jet Medallion
83%inclusion5 decks6 decks
22%synergy
Deadly Rollick
67%inclusion4 decks6 decks
43%synergy
Lashwrithe
67%inclusion4 decks6 decks
63%synergy
Sensei's Divining Top
67%inclusion4 decks6 decks
58%synergy
Bubbling Muck
67%inclusion4 decks6 decks
51%synergy
Night's Whisper
67%inclusion4 decks6 decks
42%synergy
Shadowspear
67%inclusion4 decks6 decks
63%synergy
Liliana of the Dark Realms
67%inclusion4 decks6 decks
53%synergy
Game Changers
Imperial Seal
83%inclusion5 decks6 decks
76%synergy
The One Ring
83%inclusion5 decks6 decks
74%synergy
Mana Vault
83%inclusion5 decks6 decks
77%synergy
Demonic Tutor
83%inclusion5 decks6 decks
56%synergy
Vampiric Tutor
83%inclusion5 decks6 decks
62%synergy
Ancient Tomb
67%inclusion4 decks6 decks
55%synergy
Chrome Mox
67%inclusion4 decks6 decks
61%synergy
Mox Diamond
67%inclusion4 decks6 decks
63%synergy
Opposition Agent
50%inclusion3 decks6 decks
40%synergy
Orcish Bowmasters
50%inclusion3 decks6 decks
37%synergy
Creatures
Crypt Ghast
67%inclusion4 decks6 decks
19%synergy
K'rrik, Son of Yawgmoth
67%inclusion4 decks6 decks
48%synergy
Dauthi Voidwalker
67%inclusion4 decks6 decks
51%synergy
Sheoldred, the Apocalypse
50%inclusion3 decks6 decks
35%synergy
Plague Myr
33%inclusion2 decks6 decks
32%synergy
Blightbelly Rat
33%inclusion2 decks6 decks
30%synergy
Agent Venom
25%inclusion1 decks4 decks
23%synergy
Surge Conductor
20%inclusion1 decks5 decks
20%synergy
Solemn Simulacrum
17%inclusion1 decks6 decks
-6%synergy
Contagious Nim
17%inclusion1 decks6 decks
16%synergy
Core Prowler
17%inclusion1 decks6 decks
16%synergy
Foundry Inspector
17%inclusion1 decks6 decks
13%synergy
Pestilent Syphoner
17%inclusion1 decks6 decks
16%synergy
Dark Confidant
17%inclusion1 decks6 decks
9%synergy
Reaper of Sheoldred
17%inclusion1 decks6 decks
16%synergy
Witch-king of Angmar
17%inclusion1 decks6 decks
15%synergy
Necrotic Ooze
17%inclusion1 decks6 decks
12%synergy
Gray Merchant of Asphodel
17%inclusion1 decks6 decks
-35%synergy
Defiler of Flesh
17%inclusion1 decks6 decks
13%synergy
Filth
17%inclusion1 decks6 decks
14%synergy
Phyrexian Obliterator
17%inclusion1 decks6 decks
6%synergy
Flensermite
17%inclusion1 decks6 decks
16%synergy
Ophiomancer
17%inclusion1 decks6 decks
0%synergy
Myr Convert
17%inclusion1 decks6 decks
16%synergy
Grafted Butcher
17%inclusion1 decks6 decks
16%synergy
Nirkana Revenant
17%inclusion1 decks6 decks
5%synergy
Vito, Thorn of the Dusk Rose
17%inclusion1 decks6 decks
6%synergy
Bilious Skulldweller
17%inclusion1 decks6 decks
16%synergy
Phyrexian Crusader
17%inclusion1 decks6 decks
16%synergy
Yawgmoth, Thran Physician
17%inclusion1 decks6 decks
7%synergy
Sheoldred's Headcleaver
17%inclusion1 decks6 decks
16%synergy
Flesh-Eater Imp
17%inclusion1 decks6 decks
16%synergy
Nimraiser Paladin
17%inclusion1 decks6 decks
16%synergy
Gulping Scraptrap
17%inclusion1 decks6 decks
16%synergy
Necropede
17%inclusion1 decks6 decks
16%synergy
Phyrexian Vatmother
17%inclusion1 decks6 decks
17%synergy
Hand of the Praetors
17%inclusion1 decks6 decks
16%synergy
Ichor Rats
17%inclusion1 decks6 decks
14%synergy
Instants
Vraska's Fall
50%inclusion3 decks6 decks
46%synergy
Hatred
50%inclusion3 decks6 decks
49%synergy
Culling the Weak
50%inclusion3 decks6 decks
35%synergy
Cut Down
33%inclusion2 decks6 decks
29%synergy
Whisper of the Dross
33%inclusion2 decks6 decks
30%synergy
Go for the Throat
33%inclusion2 decks6 decks
10%synergy
Imp's Mischief
33%inclusion2 decks6 decks
9%synergy
Snuff Out
33%inclusion2 decks6 decks
20%synergy
Tainted Strike
33%inclusion2 decks6 decks
30%synergy
Dismember
33%inclusion2 decks6 decks
23%synergy
Withering Torment
33%inclusion2 decks6 decks
2%synergy
Hero's Downfall
17%inclusion1 decks6 decks
10%synergy
Fell the Profane
17%inclusion1 decks6 decks
-2%synergy
Tainted Pact
17%inclusion1 decks6 decks
16%synergy
Not Dead After All
17%inclusion1 decks6 decks
5%synergy
Anoint with Affliction
17%inclusion1 decks6 decks
16%synergy
Sugar Rush
17%inclusion1 decks6 decks
16%synergy
Soul Shatter
17%inclusion1 decks6 decks
5%synergy
Slaughter Pact
17%inclusion1 decks6 decks
14%synergy
Bitter Triumph
17%inclusion1 decks6 decks
7%synergy
Virulent Swipe
17%inclusion1 decks6 decks
17%synergy
Tendrils of Corruption
17%inclusion1 decks6 decks
13%synergy
Murder
17%inclusion1 decks6 decks
6%synergy
Infernal Grasp
17%inclusion1 decks6 decks
-9%synergy
Ad Nauseam
17%inclusion1 decks6 decks
14%synergy
Sudden Spoiling
17%inclusion1 decks6 decks
8%synergy
Tragic Slip
17%inclusion1 decks6 decks
-4%synergy
Sorceries
Toxic Deluge
67%inclusion4 decks6 decks
30%synergy
Drown in Ichor
67%inclusion4 decks6 decks
63%synergy
Grim Tutor
67%inclusion4 decks6 decks
55%synergy
Crux of Fate
50%inclusion3 decks6 decks
49%synergy
Infectious Inquiry
50%inclusion3 decks6 decks
47%synergy
Dark Petition
50%inclusion3 decks6 decks
46%synergy
Sign in Blood
50%inclusion3 decks6 decks
14%synergy
Beseech the Mirror
50%inclusion3 decks6 decks
43%synergy
Beseech the Queen
50%inclusion3 decks6 decks
44%synergy
Damnation
50%inclusion3 decks6 decks
29%synergy
Diabolic Tutor
33%inclusion2 decks6 decks
19%synergy
Blasphemous Edict
33%inclusion2 decks6 decks
17%synergy
Insatiable Avarice
33%inclusion2 decks6 decks
21%synergy
Diabolic Intent
17%inclusion1 decks6 decks
2%synergy
Black Sun's Zenith
17%inclusion1 decks6 decks
11%synergy
Vat Emergence
17%inclusion1 decks6 decks
15%synergy
Peer into the Abyss
17%inclusion1 decks6 decks
6%synergy
Profane Tutor
17%inclusion1 decks6 decks
12%synergy
Torment of Hailfire
17%inclusion1 decks6 decks
1%synergy
Yawgmoth's Will
17%inclusion1 decks6 decks
13%synergy
Duress
17%inclusion1 decks6 decks
10%synergy
Mutilate
17%inclusion1 decks6 decks
-1%synergy
Praetor's Grasp
17%inclusion1 decks6 decks
13%synergy
Scheming Symmetry
17%inclusion1 decks6 decks
12%synergy
Caress of Phyrexia
17%inclusion1 decks6 decks
16%synergy
Dreams of Steel and Oil
17%inclusion1 decks6 decks
16%synergy
Reanimate
17%inclusion1 decks6 decks
-23%synergy
Disentomb
17%inclusion1 decks6 decks
16%synergy
Utility Artifacts
Mithril Coat
50%inclusion3 decks6 decks
44%synergy
Wishclaw Talisman
50%inclusion3 decks6 decks
43%synergy
Whispersilk Cloak
50%inclusion3 decks6 decks
44%synergy
Swiftfoot Boots
50%inclusion3 decks6 decks
18%synergy
Lightning Greaves
50%inclusion3 decks6 decks
16%synergy
Brotherhood Regalia
50%inclusion3 decks6 decks
47%synergy
Black Mage's Rod
40%inclusion2 decks5 decks
39%synergy
Bolas's Citadel
33%inclusion2 decks6 decks
5%synergy
Thran Power Suit
33%inclusion2 decks6 decks
33%synergy
Lavaspur Boots
33%inclusion2 decks6 decks
32%synergy
Expedition Map
33%inclusion2 decks6 decks
21%synergy
Conqueror's Flail
33%inclusion2 decks6 decks
33%synergy
Silver Shroud Costume
33%inclusion2 decks6 decks
32%synergy
Hammer of Nazahn
33%inclusion2 decks6 decks
33%synergy
Doc Ock's Tentacles
25%inclusion1 decks4 decks
25%synergy
Radiant Lotus
20%inclusion1 decks5 decks
20%synergy
The Darkness Crystal
20%inclusion1 decks5 decks
0%synergy
Genji Glove
20%inclusion1 decks5 decks
19%synergy
Umezawa's Jitte
17%inclusion1 decks6 decks
16%synergy
Crawlspace
17%inclusion1 decks6 decks
16%synergy
Defense Grid
17%inclusion1 decks6 decks
14%synergy
Cloud Key
17%inclusion1 decks6 decks
15%synergy
Sword of Fire and Ice
17%inclusion1 decks6 decks
16%synergy
Wayfarer's Bauble
17%inclusion1 decks6 decks
1%synergy
Masterwork of Ingenuity
17%inclusion1 decks6 decks
17%synergy
Skyblinder Staff
17%inclusion1 decks6 decks
17%synergy
Umbral Mantle
17%inclusion1 decks6 decks
16%synergy
Contagion Engine
17%inclusion1 decks6 decks
15%synergy
Aetherflux Reservoir
17%inclusion1 decks6 decks
7%synergy
Trailblazer's Boots
17%inclusion1 decks6 decks
14%synergy
Inspiring Statuary
17%inclusion1 decks6 decks
16%synergy
Sword of Truth and Justice
17%inclusion1 decks6 decks
16%synergy
Prosthetic Injector
17%inclusion1 decks6 decks
16%synergy
Sword of Hearth and Home
17%inclusion1 decks6 decks
15%synergy
Mystic Forge
17%inclusion1 decks6 decks
13%synergy
Winter Moon
17%inclusion1 decks6 decks
15%synergy
Pact Weapon
17%inclusion1 decks6 decks
14%synergy
Sword of Sinew and Steel
17%inclusion1 decks6 decks
16%synergy
Staff of Domination
17%inclusion1 decks6 decks
15%synergy
Sword of the Animist
17%inclusion1 decks6 decks
13%synergy
Isochron Scepter
17%inclusion1 decks6 decks
16%synergy
Hero's Blade
17%inclusion1 decks6 decks
16%synergy
Basilisk Collar
17%inclusion1 decks6 decks
14%synergy
Enchantments
The Meathook Massacre
50%inclusion3 decks6 decks
33%synergy
Unspeakable Symbol
50%inclusion3 decks6 decks
49%synergy
Phyrexian Reclamation
33%inclusion2 decks6 decks
23%synergy
Demonic Embrace
33%inclusion2 decks6 decks
32%synergy
Black Market Connections
33%inclusion2 decks6 decks
10%synergy
Heartless Summoning
33%inclusion2 decks6 decks
29%synergy
Necrogen Communion
33%inclusion2 decks6 decks
31%synergy
Super State
20%inclusion1 decks5 decks
20%synergy
Ripples of Undeath
17%inclusion1 decks6 decks
11%synergy
Contamination
17%inclusion1 decks6 decks
13%synergy
Necropotence
17%inclusion1 decks6 decks
2%synergy
Wound Reflection
17%inclusion1 decks6 decks
13%synergy
Dauthi Embrace
17%inclusion1 decks6 decks
15%synergy
No Mercy
17%inclusion1 decks6 decks
9%synergy
Endless Scream
17%inclusion1 decks6 decks
16%synergy
Fungal Fortitude
17%inclusion1 decks6 decks
15%synergy
Bloodchief Ascension
17%inclusion1 decks6 decks
7%synergy
Phyrexian Arena
17%inclusion1 decks6 decks
-23%synergy
Bitterblossom
17%inclusion1 decks6 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
50%inclusion3 decks6 decks
47%synergy
Utility Lands
Shizo, Death's Storehouse
67%inclusion4 decks6 decks
56%synergy
Cabal Coffers
67%inclusion4 decks6 decks
12%synergy
Urborg, Tomb of Yawgmoth
67%inclusion4 decks6 decks
29%synergy
The Black Gate
50%inclusion3 decks6 decks
47%synergy
Urza's Saga
50%inclusion3 decks6 decks
42%synergy
Cathedral of War
50%inclusion3 decks6 decks
50%synergy
Bojuka Bog
33%inclusion2 decks6 decks
-14%synergy
Cabal Stronghold
33%inclusion2 decks6 decks
-2%synergy
Emergence Zone
33%inclusion2 decks6 decks
30%synergy
Command Beacon
33%inclusion2 decks6 decks
25%synergy
Karn's Bastion
33%inclusion2 decks6 decks
29%synergy
Lake of the Dead
33%inclusion2 decks6 decks
28%synergy
Midgar, City of Mako
20%inclusion1 decks5 decks
8%synergy
Witch's Clinic
17%inclusion1 decks6 decks
15%synergy
Vault of Whispers
17%inclusion1 decks6 decks
11%synergy
Crystal Vein
17%inclusion1 decks6 decks
14%synergy
Fomori Vault
17%inclusion1 decks6 decks
16%synergy
Spymaster's Vault
17%inclusion1 decks6 decks
7%synergy
Geier Reach Sanitarium
17%inclusion1 decks6 decks
5%synergy
The Dross Pits
17%inclusion1 decks6 decks
15%synergy
Nykthos, Shrine to Nyx
17%inclusion1 decks6 decks
-13%synergy
Minas Morgul, Dark Fortress
17%inclusion1 decks6 decks
14%synergy
Cabal Pit
17%inclusion1 decks6 decks
16%synergy
Peat Bog
17%inclusion1 decks6 decks
15%synergy
Temple of the False God
17%inclusion1 decks6 decks
9%synergy
Strip Mine
17%inclusion1 decks6 decks
14%synergy
Mana Artifacts
Sol Ring
100%inclusion6 decks6 decks
14%synergy
Arcane Signet
83%inclusion5 decks6 decks
21%synergy
Mox Opal
83%inclusion5 decks6 decks
80%synergy
Lotus Petal
67%inclusion4 decks6 decks
59%synergy
Mox Jasper
60%inclusion3 decks5 decks
60%synergy
Staff of Compleation
50%inclusion3 decks6 decks
48%synergy
Mox Amber
50%inclusion3 decks6 decks
46%synergy
The Soul Stone
40%inclusion2 decks5 decks
26%synergy
Heraldic Banner
33%inclusion2 decks6 decks
28%synergy
Fellwar Stone
33%inclusion2 decks6 decks
19%synergy
Mind Stone
33%inclusion2 decks6 decks
4%synergy
Charcoal Diamond
17%inclusion1 decks6 decks
-6%synergy
Glistening Sphere
17%inclusion1 decks6 decks
15%synergy
Patchwork Banner
17%inclusion1 decks6 decks
12%synergy
Mox Tantalite
17%inclusion1 decks6 decks
16%synergy
Extraplanar Lens
17%inclusion1 decks6 decks
12%synergy
Lands
Swamp
100%inclusion6 decks6 decks
5%synergy
Verdant Catacombs
50%inclusion3 decks6 decks
47%synergy
Cavern of Souls
50%inclusion3 decks6 decks
43%synergy
Marsh Flats
50%inclusion3 decks6 decks
47%synergy
Polluted Delta
50%inclusion3 decks6 decks
47%synergy
Bloodstained Mire
50%inclusion3 decks6 decks
46%synergy
Prismatic Vista
33%inclusion2 decks6 decks
31%synergy
The Mycosynth Gardens
33%inclusion2 decks6 decks
32%synergy
Command Tower
33%inclusion2 decks6 decks
28%synergy
Gemstone Caverns
33%inclusion2 decks6 decks
29%synergy
Fell the Profane
17%inclusion1 decks6 decks
-2%synergy
Fabled Passage
17%inclusion1 decks6 decks
15%synergy
Urza's Cave
17%inclusion1 decks6 decks
8%synergy
Mirrex
17%inclusion1 decks6 decks
16%synergy
Plaza of Heroes
17%inclusion1 decks6 decks
16%synergy
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