Skithiryx, the Blight Dragon (Commander) - Optimized

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
91decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
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Splinter's Technique
25%inclusion1 decks4 decks
25%synergy
Bitterbloom Bearer
2.2%inclusion1 decks45 decks
-1%synergy
High Synergy Cards
Plague Myr
63%inclusion57 decks91 decks
61%synergy
Plague Stinger
62%inclusion56 decks91 decks
61%synergy
Lashwrithe
59%inclusion54 decks91 decks
55%synergy
Infectious Inquiry
57%inclusion52 decks91 decks
54%synergy
Whispering Specter
53%inclusion48 decks91 decks
52%synergy
Commander's Plate
56%inclusion51 decks91 decks
50%synergy
Shizo, Death's Storehouse
60%inclusion55 decks91 decks
50%synergy
Inkmoth Nexus
51%inclusion46 decks91 decks
50%synergy
Phyrexian Crusader
48%inclusion44 decks91 decks
47%synergy
Vraska's Fall
48%inclusion44 decks91 decks
45%synergy
Top Cards
Dark Ritual
90%inclusion82 decks91 decks
24%synergy
Jet Medallion
82%inclusion75 decks91 decks
22%synergy
Deadly Rollick
60%inclusion55 decks91 decks
37%synergy
Phyrexian Arena
60%inclusion55 decks91 decks
20%synergy
Crypt Ghast
60%inclusion55 decks91 decks
12%synergy
Toxic Deluge
55%inclusion50 decks91 decks
18%synergy
Cabal Ritual
54%inclusion49 decks91 decks
36%synergy
Feed the Swarm
52%inclusion47 decks91 decks
1%synergy
Black Market Connections
51%inclusion46 decks91 decks
27%synergy
Lightning Greaves
47%inclusion43 decks91 decks
14%synergy
Game Changers
Demonic Tutor
77%inclusion70 decks91 decks
49%synergy
Vampiric Tutor
69%inclusion63 decks91 decks
48%synergy
Ancient Tomb
56%inclusion51 decks91 decks
44%synergy
Necropotence
54%inclusion49 decks91 decks
39%synergy
Mana Vault
49%inclusion45 decks91 decks
43%synergy
Opposition Agent
46%inclusion42 decks91 decks
36%synergy
The One Ring
44%inclusion40 decks91 decks
34%synergy
Chrome Mox
41%inclusion37 decks91 decks
35%synergy
Bolas's Citadel
40%inclusion36 decks91 decks
10%synergy
Orcish Bowmasters
38%inclusion35 decks91 decks
25%synergy
Creatures
Ichor Rats
47%inclusion43 decks91 decks
44%synergy
Hand of the Praetors
45%inclusion41 decks91 decks
44%synergy
Dauthi Voidwalker
43%inclusion39 decks91 decks
27%synergy
Sheoldred, the Apocalypse
34%inclusion31 decks91 decks
19%synergy
Phyrexian Obliterator
30%inclusion27 decks91 decks
19%synergy
K'rrik, Son of Yawgmoth
30%inclusion27 decks91 decks
11%synergy
Gray Merchant of Asphodel
27%inclusion25 decks91 decks
-24%synergy
Flesh-Eater Imp
27%inclusion25 decks91 decks
27%synergy
Yawgmoth, Thran Physician
25%inclusion23 decks91 decks
15%synergy
Dark Confidant
23%inclusion21 decks91 decks
16%synergy
Blightbelly Rat
23%inclusion21 decks91 decks
19%synergy
Flensermite
21%inclusion19 decks91 decks
20%synergy
Pestilent Syphoner
16%inclusion15 decks91 decks
16%synergy
Myr Convert
16%inclusion15 decks91 decks
16%synergy
Ichorclaw Myr
16%inclusion15 decks91 decks
16%synergy
Reaper of Sheoldred
15%inclusion14 decks91 decks
15%synergy
Solemn Simulacrum
14%inclusion13 decks91 decks
-9%synergy
Nirkana Revenant
14%inclusion13 decks91 decks
3%synergy
Magus of the Coffers
13%inclusion12 decks91 decks
6%synergy
Corpse Cur
13%inclusion12 decks91 decks
13%synergy
Septic Rats
13%inclusion12 decks91 decks
11%synergy
Bilious Skulldweller
13%inclusion12 decks91 decks
12%synergy
Sheoldred, Whispering One
12%inclusion11 decks91 decks
0%synergy
Blood Pet
12%inclusion11 decks91 decks
4%synergy
Blightsteel Colossus
12%inclusion11 decks91 decks
11%synergy
Core Prowler
11%inclusion10 decks91 decks
10%synergy
Gwenom, Remorseless
8.9%inclusion5 decks56 decks
6%synergy
Massacre Wurm
8.8%inclusion8 decks91 decks
-9%synergy
Agent Venom
7.8%inclusion4 decks51 decks
6%synergy
Leaden Myr
7.7%inclusion7 decks91 decks
1%synergy
Contagious Nim
6.6%inclusion6 decks91 decks
6%synergy
Dread Presence
6.6%inclusion6 decks91 decks
-8%synergy
Silent Arbiter
6.6%inclusion6 decks91 decks
5%synergy
Maha, Its Feathers Night
6.6%inclusion6 decks91 decks
2%synergy
Grafted Butcher
6.6%inclusion6 decks91 decks
6%synergy
Toxic Nim
6.6%inclusion6 decks91 decks
6%synergy
Gulping Scraptrap
6.6%inclusion6 decks91 decks
6%synergy
Vito, Thorn of the Dusk Rose
6.6%inclusion6 decks91 decks
-4%synergy
Scheming Aspirant
6.6%inclusion6 decks91 decks
6%synergy
Phyrexian Vatmother
6.6%inclusion6 decks91 decks
6%synergy
Ornithopter of Paradise
5.5%inclusion5 decks91 decks
3%synergy
Necroskitter
5.5%inclusion5 decks91 decks
2%synergy
Necropede
5.5%inclusion5 decks91 decks
5%synergy
Gix, Yawgmoth Praetor
5.5%inclusion5 decks91 decks
0%synergy
Bloodgift Demon
5.5%inclusion5 decks91 decks
2%synergy
Surge Conductor
5.1%inclusion3 decks59 decks
5%synergy
Instants
Imp's Mischief
46%inclusion42 decks91 decks
22%synergy
Dismember
42%inclusion38 decks91 decks
31%synergy
Howl from Beyond
38%inclusion35 decks91 decks
38%synergy
Withering Torment
38%inclusion34 decks90 decks
6%synergy
Infernal Grasp
35%inclusion32 decks91 decks
10%synergy
Malakir Rebirth
32%inclusion29 decks91 decks
9%synergy
Go for the Throat
31%inclusion28 decks91 decks
8%synergy
Hatred
27%inclusion25 decks91 decks
26%synergy
Snuff Out
27%inclusion25 decks91 decks
15%synergy
Tainted Strike
26%inclusion24 decks91 decks
23%synergy
Astarion's Thirst
22%inclusion20 decks91 decks
20%synergy
Defile
22%inclusion20 decks91 decks
-15%synergy
Sudden Spoiling
22%inclusion20 decks91 decks
13%synergy
Whisper of the Dross
21%inclusion19 decks91 decks
18%synergy
Cut Down
21%inclusion19 decks91 decks
17%synergy
Baleful Mastery
21%inclusion19 decks91 decks
12%synergy
Withering Boon
21%inclusion19 decks91 decks
16%synergy
Darkness
18%inclusion16 decks91 decks
8%synergy
Grim Affliction
16%inclusion15 decks91 decks
14%synergy
Fell the Profane
15%inclusion14 decks91 decks
-3%synergy
Culling the Weak
15%inclusion14 decks91 decks
0%synergy
Archenemy's Charm
15%inclusion9 decks61 decks
6%synergy
Hero's Downfall
14%inclusion13 decks91 decks
7%synergy
Bitter Triumph
13%inclusion12 decks91 decks
3%synergy
Force of Despair
12%inclusion11 decks91 decks
4%synergy
Sheoldred's Edict
11%inclusion10 decks91 decks
-3%synergy
Supernatural Stamina
8.8%inclusion8 decks91 decks
1%synergy
Virulent Wound
8.8%inclusion8 decks91 decks
8%synergy
Tragic Slip
8.8%inclusion8 decks91 decks
-12%synergy
Sugar Rush
7.7%inclusion7 decks91 decks
7%synergy
Slaughter Pact
7.7%inclusion7 decks91 decks
5%synergy
Murder
7.7%inclusion7 decks91 decks
-3%synergy
Soul Shatter
6.6%inclusion6 decks91 decks
-6%synergy
Ad Nauseam
6.6%inclusion6 decks91 decks
4%synergy
Anoint with Affliction
5.5%inclusion5 decks91 decks
5%synergy
Unlikely Aid
5.5%inclusion5 decks91 decks
5%synergy
Doom Blade
5.5%inclusion5 decks91 decks
-2%synergy
Sorceries
Phyresis Outbreak
46%inclusion42 decks91 decks
44%synergy
Damnation
45%inclusion41 decks91 decks
24%synergy
Bubbling Muck
44%inclusion40 decks91 decks
28%synergy
Drown in Ichor
43%inclusion39 decks91 decks
39%synergy
Crux of Fate
42%inclusion38 decks91 decks
40%synergy
Night's Whisper
38%inclusion35 decks91 decks
14%synergy
Grim Tutor
35%inclusion32 decks91 decks
23%synergy
Imperial Seal
33%inclusion30 decks91 decks
26%synergy
Sign in Blood
32%inclusion29 decks91 decks
-4%synergy
Reanimate
26%inclusion24 decks91 decks
-13%synergy
Caress of Phyrexia
20%inclusion18 decks91 decks
19%synergy
Mutilate
16%inclusion15 decks91 decks
-2%synergy
Read the Bones
15%inclusion14 decks91 decks
-2%synergy
Insatiable Avarice
15%inclusion14 decks91 decks
3%synergy
Black Sun's Zenith
14%inclusion13 decks91 decks
8%synergy
Diabolic Tutor
14%inclusion13 decks91 decks
0%synergy
Beseech the Mirror
14%inclusion13 decks91 decks
7%synergy
Profane Tutor
13%inclusion12 decks91 decks
9%synergy
Torment of Hailfire
13%inclusion12 decks91 decks
-3%synergy
Praetor's Grasp
13%inclusion12 decks91 decks
9%synergy
Beseech the Queen
13%inclusion12 decks91 decks
7%synergy
Blasphemous Edict
13%inclusion11 decks87 decks
-4%synergy
Vat Emergence
12%inclusion11 decks91 decks
11%synergy
Gix's Command
12%inclusion11 decks91 decks
10%synergy
Exsanguinate
11%inclusion10 decks91 decks
-13%synergy
Peer into the Abyss
7.7%inclusion7 decks91 decks
-3%synergy
Spread the Sickness
6.6%inclusion6 decks91 decks
6%synergy
Victimize
6.6%inclusion6 decks91 decks
-19%synergy
Yawgmoth's Will
6.6%inclusion6 decks91 decks
3%synergy
Duress
6.6%inclusion6 decks91 decks
0%synergy
Syphon Mind
6.6%inclusion6 decks91 decks
-6%synergy
Thoughtseize
6.6%inclusion6 decks91 decks
2%synergy
Dark Petition
5.5%inclusion5 decks91 decks
2%synergy
Rise of the Dark Realms
5.5%inclusion5 decks91 decks
-7%synergy
Decree of Pain
5.5%inclusion5 decks91 decks
0%synergy
Utility Artifacts
Nightmare Lash
46%inclusion42 decks91 decks
44%synergy
Swiftfoot Boots
46%inclusion42 decks91 decks
15%synergy
Shadowspear
43%inclusion39 decks91 decks
39%synergy
Blackblade Reforged
37%inclusion34 decks91 decks
34%synergy
Sword of Truth and Justice
32%inclusion29 decks91 decks
31%synergy
Whispersilk Cloak
27%inclusion25 decks91 decks
22%synergy
Contagion Engine
27%inclusion25 decks91 decks
25%synergy
Champion's Helm
25%inclusion23 decks91 decks
23%synergy
The Darkness Crystal
24%inclusion16 decks68 decks
4%synergy
Sensei's Divining Top
22%inclusion20 decks91 decks
14%synergy
Fireshrieker
22%inclusion20 decks91 decks
20%synergy
Pact Weapon
22%inclusion20 decks91 decks
20%synergy
Leyline Axe
22%inclusion19 decks87 decks
21%synergy
Contagion Clasp
19%inclusion17 decks91 decks
16%synergy
Cranial Plating
19%inclusion17 decks91 decks
15%synergy
Expedition Map
19%inclusion17 decks91 decks
6%synergy
Doc Ock's Tentacles
18%inclusion9 decks50 decks
18%synergy
Mithril Coat
18%inclusion16 decks91 decks
12%synergy
Sword of the Animist
18%inclusion16 decks91 decks
14%synergy
Wishclaw Talisman
16%inclusion15 decks91 decks
10%synergy
Sword of Feast and Famine
16%inclusion15 decks91 decks
15%synergy
Hammer of Nazahn
16%inclusion15 decks91 decks
16%synergy
Sword of Wealth and Power
14%inclusion13 decks91 decks
14%synergy
Buster Sword
13%inclusion9 decks68 decks
12%synergy
Brotherhood Regalia
13%inclusion12 decks91 decks
11%synergy
Thran Power Suit
10%inclusion9 decks91 decks
10%synergy
Whip of Erebos
10%inclusion9 decks91 decks
-1%synergy
Silver Shroud Costume
10%inclusion9 decks91 decks
9%synergy
Strata Scythe
10%inclusion9 decks91 decks
9%synergy
Genji Glove
9.1%inclusion6 decks66 decks
8%synergy
Trailblazer's Boots
8.8%inclusion8 decks91 decks
7%synergy
Hero's Blade
8.8%inclusion8 decks91 decks
8%synergy
Aetherflux Reservoir
8.8%inclusion8 decks91 decks
-1%synergy
Bontu's Monument
8.8%inclusion8 decks91 decks
-19%synergy
Loxodon Warhammer
8.8%inclusion8 decks91 decks
7%synergy
Wayfarer's Bauble
7.7%inclusion7 decks91 decks
-8%synergy
Manifold Key
7.7%inclusion7 decks91 decks
6%synergy
O-Naginata
7.7%inclusion7 decks91 decks
7%synergy
Grafted Exoskeleton
7.7%inclusion7 decks91 decks
7%synergy
Strength-Testing Hammer
6.6%inclusion6 decks91 decks
7%synergy
Vorpal Sword
6.6%inclusion6 decks91 decks
3%synergy
Inquisitor's Flail
6.6%inclusion6 decks91 decks
6%synergy
Sword of Vengeance
6.6%inclusion6 decks91 decks
6%synergy
Conqueror's Flail
5.5%inclusion5 decks91 decks
5%synergy
Sword of Hearth and Home
5.5%inclusion5 decks91 decks
4%synergy
Enchantments
Unspeakable Symbol
44%inclusion40 decks91 decks
43%synergy
Necrogen Communion
27%inclusion25 decks91 decks
26%synergy
Kaya's Ghostform
22%inclusion20 decks91 decks
12%synergy
Phyresis
19%inclusion17 decks91 decks
17%synergy
No Mercy
16%inclusion15 decks91 decks
9%synergy
Contamination
15%inclusion14 decks91 decks
12%synergy
The Meathook Massacre
13%inclusion12 decks91 decks
-4%synergy
Animate Dead
13%inclusion12 decks91 decks
-4%synergy
Super State
11%inclusion7 decks63 decks
11%synergy
Haunted One
10%inclusion9 decks91 decks
7%synergy
Dauthi Embrace
10%inclusion9 decks91 decks
8%synergy
Oubliette
10%inclusion9 decks91 decks
7%synergy
Bitterblossom
10%inclusion9 decks91 decks
-3%synergy
Black Market
8.8%inclusion8 decks91 decks
-12%synergy
Endless Scream
8.8%inclusion8 decks91 decks
9%synergy
Snake Cult Initiation
8.8%inclusion8 decks91 decks
9%synergy
Alien Symbiosis
8.0%inclusion4 decks50 decks
8%synergy
Glistening Oil
7.7%inclusion7 decks91 decks
7%synergy
Exquisite Blood
7.7%inclusion7 decks91 decks
-6%synergy
Phyrexian Reclamation
7.7%inclusion7 decks91 decks
-2%synergy
Bad Moon
7.7%inclusion7 decks91 decks
4%synergy
Relic Putrescence
6.6%inclusion6 decks91 decks
6%synergy
Infernal Darkness
6.6%inclusion6 decks91 decks
6%synergy
Leyline of the Void
6.6%inclusion6 decks91 decks
5%synergy
Shade's Form
5.5%inclusion5 decks91 decks
5%synergy
Fungal Fortitude
5.5%inclusion5 decks91 decks
4%synergy
Demonic Embrace
5.5%inclusion5 decks91 decks
5%synergy
Planeswalkers
Liliana of the Dark Realms
43%inclusion39 decks91 decks
29%synergy
Vraska, Betrayal's Sting
38%inclusion35 decks91 decks
36%synergy
Tezzeret, Cruel Captain
6.3%inclusion4 decks64 decks
5%synergy
Utility Lands
Cabal Coffers
82%inclusion75 decks91 decks
27%synergy
Urborg, Tomb of Yawgmoth
77%inclusion70 decks91 decks
39%synergy
Rogue's Passage
54%inclusion49 decks91 decks
35%synergy
Karn's Bastion
45%inclusion41 decks91 decks
41%synergy
Urza's Saga
37%inclusion34 decks91 decks
29%synergy
Cabal Stronghold
36%inclusion33 decks91 decks
1%synergy
Bojuka Bog
35%inclusion32 decks91 decks
-12%synergy
Nykthos, Shrine to Nyx
26%inclusion24 decks91 decks
-3%synergy
The Black Gate
25%inclusion23 decks91 decks
22%synergy
Command Beacon
16%inclusion15 decks91 decks
8%synergy
Phyrexian Tower
15%inclusion14 decks91 decks
-9%synergy
Castle Locthwain
15%inclusion14 decks91 decks
-2%synergy
Lake of the Dead
15%inclusion14 decks91 decks
10%synergy
Strip Mine
14%inclusion13 decks91 decks
11%synergy
Cathedral of War
13%inclusion12 decks91 decks
13%synergy
Reliquary Tower
13%inclusion12 decks91 decks
-18%synergy
Takenuma, Abandoned Mire
13%inclusion12 decks91 decks
-3%synergy
Homeward Path
12%inclusion11 decks91 decks
10%synergy
War Room
11%inclusion10 decks91 decks
-5%synergy
Minas Morgul, Dark Fortress
10%inclusion9 decks91 decks
7%synergy
Vault of Whispers
7.7%inclusion7 decks91 decks
2%synergy
Temple of the False God
7.7%inclusion7 decks91 decks
0%synergy
Deserted Temple
7.7%inclusion7 decks91 decks
3%synergy
Mortuary Mire
6.6%inclusion6 decks91 decks
-7%synergy
Witch's Cottage
6.6%inclusion6 decks91 decks
-18%synergy
Emergence Zone
6.6%inclusion6 decks91 decks
3%synergy
Inventors' Fair
6.6%inclusion6 decks91 decks
4%synergy
Wasteland
5.5%inclusion5 decks91 decks
4%synergy
Barren Moor
5.5%inclusion5 decks91 decks
-5%synergy
Buried Ruin
5.5%inclusion5 decks91 decks
0%synergy
Crystal Vein
5.5%inclusion5 decks91 decks
3%synergy
Ghost Quarter
5.5%inclusion5 decks91 decks
3%synergy
Arcane Lighthouse
5.5%inclusion5 decks91 decks
4%synergy
Thespian's Stage
5.5%inclusion5 decks91 decks
0%synergy
Mana Artifacts
Sol Ring
97%inclusion88 decks91 decks
10%synergy
Arcane Signet
68%inclusion62 decks91 decks
6%synergy
Mox Opal
42%inclusion38 decks91 decks
38%synergy
Lotus Petal
40%inclusion36 decks91 decks
32%synergy
The Soul Stone
39%inclusion22 decks56 decks
26%synergy
Mox Diamond
30%inclusion27 decks91 decks
26%synergy
Glistening Sphere
27%inclusion25 decks91 decks
26%synergy
Mind Stone
24%inclusion22 decks91 decks
-6%synergy
Fellwar Stone
24%inclusion22 decks91 decks
9%synergy
Grim Monolith
23%inclusion21 decks91 decks
20%synergy
Staff of Compleation
22%inclusion20 decks91 decks
20%synergy
Throne of Eldraine
19%inclusion17 decks91 decks
8%synergy
Heraldic Banner
18%inclusion16 decks91 decks
12%synergy
Thought Vessel
16%inclusion15 decks91 decks
-10%synergy
Caged Sun
15%inclusion14 decks91 decks
3%synergy
Mox Amber
14%inclusion13 decks91 decks
10%synergy
Mox Jasper
12%inclusion10 decks82 decks
12%synergy
Extraplanar Lens
12%inclusion11 decks91 decks
7%synergy
Charcoal Diamond
10%inclusion9 decks91 decks
-13%synergy
Thran Dynamo
8.8%inclusion8 decks91 decks
3%synergy
Patchwork Banner
8.8%inclusion8 decks91 decks
5%synergy
Gilded Lotus
7.7%inclusion7 decks91 decks
2%synergy
Sceptre of Eternal Glory
7.7%inclusion7 decks91 decks
-1%synergy
Everflowing Chalice
6.6%inclusion6 decks91 decks
1%synergy
Gauntlet of Power
6.6%inclusion6 decks91 decks
3%synergy
Mox Tantalite
5.5%inclusion5 decks91 decks
5%synergy
Lands
Swamp
95%inclusion86 decks91 decks
0%synergy
Cavern of Souls
36%inclusion33 decks91 decks
30%synergy
Malakir Rebirth
32%inclusion29 decks91 decks
9%synergy
Gemstone Caverns
25%inclusion23 decks91 decks
21%synergy
Fell the Profane
15%inclusion14 decks91 decks
-3%synergy
Mirrex
14%inclusion13 decks91 decks
14%synergy
Marsh Flats
14%inclusion13 decks91 decks
11%synergy
Polluted Delta
14%inclusion13 decks91 decks
11%synergy
Bloodstained Mire
14%inclusion13 decks91 decks
11%synergy
Myriad Landscape
13%inclusion12 decks91 decks
-13%synergy
Verdant Catacombs
13%inclusion12 decks91 decks
10%synergy
Urza's Cave
8.8%inclusion8 decks91 decks
0%synergy
Command Tower
7.7%inclusion7 decks91 decks
2%synergy
Snow-Covered Swamp
7.7%inclusion7 decks91 decks
1%synergy
Prismatic Vista
5.5%inclusion5 decks91 decks
3%synergy
Talon Gates of Madara
5.5%inclusion5 decks91 decks
4%synergy
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