Skithiryx, the Blight Dragon (Commander) - Optimized

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #781
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Splinter's Technique
9.1%inclusion1 decks11 decks
9%synergy
Bitterbloom Bearer
2.0%inclusion1 decks49 decks
-2%synergy
High Synergy Cards
Plague Myr
63%inclusion59 decks94 decks
61%synergy
Plague Stinger
62%inclusion58 decks94 decks
61%synergy
Lashwrithe
60%inclusion56 decks94 decks
56%synergy
Whispering Specter
54%inclusion51 decks94 decks
54%synergy
Infectious Inquiry
56%inclusion53 decks94 decks
53%synergy
Shizo, Death's Storehouse
61%inclusion57 decks94 decks
51%synergy
Commander's Plate
55%inclusion52 decks94 decks
50%synergy
Phyrexian Crusader
49%inclusion46 decks94 decks
48%synergy
Inkmoth Nexus
49%inclusion46 decks94 decks
48%synergy
Hand of the Praetors
46%inclusion43 decks94 decks
45%synergy
Top Cards
Dark Ritual
90%inclusion85 decks94 decks
24%synergy
Jet Medallion
82%inclusion77 decks94 decks
21%synergy
Phyrexian Arena
63%inclusion59 decks94 decks
23%synergy
Crypt Ghast
61%inclusion57 decks94 decks
12%synergy
Deadly Rollick
60%inclusion56 decks94 decks
36%synergy
Toxic Deluge
54%inclusion51 decks94 decks
17%synergy
Cabal Ritual
54%inclusion51 decks94 decks
36%synergy
Feed the Swarm
53%inclusion50 decks94 decks
2%synergy
Black Market Connections
51%inclusion48 decks94 decks
28%synergy
Swiftfoot Boots
49%inclusion46 decks94 decks
17%synergy
Game Changers
Demonic Tutor
78%inclusion73 decks94 decks
50%synergy
Vampiric Tutor
69%inclusion65 decks94 decks
48%synergy
Ancient Tomb
55%inclusion52 decks94 decks
44%synergy
Necropotence
54%inclusion51 decks94 decks
39%synergy
Mana Vault
49%inclusion46 decks94 decks
42%synergy
Opposition Agent
47%inclusion44 decks94 decks
37%synergy
The One Ring
44%inclusion41 decks94 decks
34%synergy
Chrome Mox
40%inclusion38 decks94 decks
34%synergy
Bolas's Citadel
40%inclusion38 decks94 decks
11%synergy
Orcish Bowmasters
37%inclusion35 decks94 decks
24%synergy
Creatures
Ichor Rats
48%inclusion45 decks94 decks
45%synergy
Dauthi Voidwalker
44%inclusion41 decks94 decks
28%synergy
Sheoldred, the Apocalypse
32%inclusion30 decks94 decks
17%synergy
K'rrik, Son of Yawgmoth
30%inclusion28 decks94 decks
11%synergy
Phyrexian Obliterator
29%inclusion27 decks94 decks
18%synergy
Gray Merchant of Asphodel
28%inclusion26 decks94 decks
-24%synergy
Flesh-Eater Imp
27%inclusion25 decks94 decks
26%synergy
Yawgmoth, Thran Physician
23%inclusion22 decks94 decks
13%synergy
Blightbelly Rat
23%inclusion22 decks94 decks
20%synergy
Flensermite
21%inclusion20 decks94 decks
21%synergy
Dark Confidant
21%inclusion20 decks94 decks
14%synergy
Myr Convert
17%inclusion16 decks94 decks
16%synergy
Ichorclaw Myr
17%inclusion16 decks94 decks
17%synergy
Pestilent Syphoner
16%inclusion15 decks94 decks
15%synergy
Reaper of Sheoldred
16%inclusion15 decks94 decks
15%synergy
Solemn Simulacrum
15%inclusion14 decks94 decks
-8%synergy
Septic Rats
15%inclusion14 decks94 decks
13%synergy
Nirkana Revenant
14%inclusion13 decks94 decks
2%synergy
Corpse Cur
14%inclusion13 decks94 decks
13%synergy
Core Prowler
13%inclusion12 decks94 decks
12%synergy
Magus of the Coffers
13%inclusion12 decks94 decks
6%synergy
Bilious Skulldweller
13%inclusion12 decks94 decks
12%synergy
Blood Pet
13%inclusion12 decks94 decks
5%synergy
Sheoldred, Whispering One
12%inclusion11 decks94 decks
0%synergy
Blightsteel Colossus
12%inclusion11 decks94 decks
11%synergy
Gwenom, Remorseless
10%inclusion6 decks60 decks
7%synergy
Massacre Wurm
8.5%inclusion8 decks94 decks
-9%synergy
Leaden Myr
7.4%inclusion7 decks94 decks
1%synergy
Phyrexian Vatmother
6.4%inclusion6 decks94 decks
6%synergy
Dread Presence
6.4%inclusion6 decks94 decks
-8%synergy
Silent Arbiter
6.4%inclusion6 decks94 decks
5%synergy
Grafted Butcher
6.4%inclusion6 decks94 decks
6%synergy
Vito, Thorn of the Dusk Rose
6.4%inclusion6 decks94 decks
-4%synergy
Scheming Aspirant
6.4%inclusion6 decks94 decks
6%synergy
Gulping Scraptrap
6.4%inclusion6 decks94 decks
6%synergy
Contagious Nim
6.4%inclusion6 decks94 decks
6%synergy
Toxic Nim
6.4%inclusion6 decks94 decks
6%synergy
Agent Venom
5.5%inclusion3 decks55 decks
3%synergy
Phyrexian Juggernaut
5.3%inclusion5 decks94 decks
5%synergy
Maha, Its Feathers Night
5.3%inclusion5 decks94 decks
1%synergy
Ornithopter of Paradise
5.3%inclusion5 decks94 decks
2%synergy
Necropede
5.3%inclusion5 decks94 decks
5%synergy
Bloodgift Demon
5.3%inclusion5 decks94 decks
2%synergy
Instants
Vraska's Fall
48%inclusion45 decks94 decks
44%synergy
Imp's Mischief
46%inclusion43 decks94 decks
21%synergy
Dismember
43%inclusion40 decks94 decks
32%synergy
Infernal Grasp
39%inclusion37 decks94 decks
14%synergy
Howl from Beyond
38%inclusion36 decks94 decks
38%synergy
Withering Torment
38%inclusion35 decks93 decks
6%synergy
Go for the Throat
33%inclusion31 decks94 decks
10%synergy
Malakir Rebirth
32%inclusion30 decks94 decks
9%synergy
Snuff Out
29%inclusion27 decks94 decks
16%synergy
Tainted Strike
29%inclusion27 decks94 decks
26%synergy
Hatred
27%inclusion25 decks94 decks
26%synergy
Astarion's Thirst
23%inclusion22 decks94 decks
22%synergy
Cut Down
22%inclusion21 decks94 decks
18%synergy
Defile
21%inclusion20 decks94 decks
-16%synergy
Baleful Mastery
21%inclusion20 decks94 decks
12%synergy
Whisper of the Dross
21%inclusion20 decks94 decks
18%synergy
Withering Boon
21%inclusion20 decks94 decks
17%synergy
Sudden Spoiling
20%inclusion19 decks94 decks
11%synergy
Darkness
17%inclusion16 decks94 decks
7%synergy
Culling the Weak
16%inclusion15 decks94 decks
1%synergy
Grim Affliction
16%inclusion15 decks94 decks
14%synergy
Fell the Profane
15%inclusion14 decks94 decks
-4%synergy
Archenemy's Charm
14%inclusion9 decks65 decks
5%synergy
Hero's Downfall
14%inclusion13 decks94 decks
7%synergy
Bitter Triumph
14%inclusion13 decks94 decks
4%synergy
Sheoldred's Edict
12%inclusion11 decks94 decks
-3%synergy
Force of Despair
12%inclusion11 decks94 decks
4%synergy
Sugar Rush
8.5%inclusion8 decks94 decks
8%synergy
Virulent Wound
8.5%inclusion8 decks94 decks
8%synergy
Supernatural Stamina
8.5%inclusion8 decks94 decks
1%synergy
Murder
7.4%inclusion7 decks94 decks
-3%synergy
Tragic Slip
7.4%inclusion7 decks94 decks
-13%synergy
Doom Blade
6.4%inclusion6 decks94 decks
-1%synergy
Soul Shatter
6.4%inclusion6 decks94 decks
-6%synergy
Slaughter Pact
6.4%inclusion6 decks94 decks
4%synergy
Ad Nauseam
6.4%inclusion6 decks94 decks
4%synergy
Unlikely Aid
5.3%inclusion5 decks94 decks
5%synergy
Anoint with Affliction
5.3%inclusion5 decks94 decks
5%synergy
Sorceries
Bubbling Muck
46%inclusion43 decks94 decks
30%synergy
Phyresis Outbreak
46%inclusion43 decks94 decks
44%synergy
Damnation
44%inclusion41 decks94 decks
23%synergy
Crux of Fate
43%inclusion40 decks94 decks
41%synergy
Night's Whisper
40%inclusion38 decks94 decks
16%synergy
Drown in Ichor
40%inclusion38 decks94 decks
36%synergy
Grim Tutor
37%inclusion35 decks94 decks
25%synergy
Sign in Blood
34%inclusion32 decks94 decks
-2%synergy
Imperial Seal
33%inclusion31 decks94 decks
26%synergy
Reanimate
29%inclusion27 decks94 decks
-11%synergy
Caress of Phyrexia
20%inclusion19 decks94 decks
20%synergy
Diabolic Tutor
16%inclusion15 decks94 decks
1%synergy
Read the Bones
16%inclusion15 decks94 decks
-2%synergy
Mutilate
16%inclusion15 decks94 decks
-2%synergy
Insatiable Avarice
16%inclusion15 decks94 decks
4%synergy
Profane Tutor
14%inclusion13 decks94 decks
9%synergy
Beseech the Mirror
14%inclusion13 decks94 decks
7%synergy
Praetor's Grasp
14%inclusion13 decks94 decks
10%synergy
Gix's Command
13%inclusion12 decks94 decks
11%synergy
Black Sun's Zenith
13%inclusion12 decks94 decks
7%synergy
Torment of Hailfire
13%inclusion12 decks94 decks
-3%synergy
Beseech the Queen
13%inclusion12 decks94 decks
7%synergy
Blasphemous Edict
12%inclusion11 decks90 decks
-5%synergy
Exsanguinate
12%inclusion11 decks94 decks
-13%synergy
Vat Emergence
11%inclusion10 decks94 decks
9%synergy
Peer into the Abyss
8.5%inclusion8 decks94 decks
-2%synergy
Duress
7.4%inclusion7 decks94 decks
1%synergy
Victimize
7.4%inclusion7 decks94 decks
-19%synergy
Spread the Sickness
6.4%inclusion6 decks94 decks
6%synergy
Yawgmoth's Will
6.4%inclusion6 decks94 decks
3%synergy
Thoughtseize
6.4%inclusion6 decks94 decks
1%synergy
Syphon Mind
6.4%inclusion6 decks94 decks
-6%synergy
Dark Petition
5.3%inclusion5 decks94 decks
1%synergy
Decree of Pain
5.3%inclusion5 decks94 decks
0%synergy
Scheming Symmetry
5.3%inclusion5 decks94 decks
1%synergy
Rise of the Dark Realms
5.3%inclusion5 decks94 decks
-7%synergy
Utility Artifacts
Lightning Greaves
48%inclusion45 decks94 decks
14%synergy
Nightmare Lash
46%inclusion43 decks94 decks
43%synergy
Shadowspear
43%inclusion40 decks94 decks
39%synergy
Blackblade Reforged
41%inclusion39 decks94 decks
39%synergy
Sword of Truth and Justice
31%inclusion29 decks94 decks
30%synergy
Whispersilk Cloak
29%inclusion27 decks94 decks
23%synergy
Contagion Engine
27%inclusion25 decks94 decks
25%synergy
Champion's Helm
26%inclusion24 decks94 decks
24%synergy
The Darkness Crystal
24%inclusion17 decks71 decks
4%synergy
Leyline Axe
23%inclusion21 decks90 decks
22%synergy
Fireshrieker
22%inclusion21 decks94 decks
20%synergy
Pact Weapon
22%inclusion21 decks94 decks
20%synergy
Sensei's Divining Top
21%inclusion20 decks94 decks
13%synergy
Cranial Plating
19%inclusion18 decks94 decks
16%synergy
Expedition Map
19%inclusion18 decks94 decks
7%synergy
Contagion Clasp
18%inclusion17 decks94 decks
16%synergy
Hammer of Nazahn
17%inclusion16 decks94 decks
16%synergy
Sword of Feast and Famine
17%inclusion16 decks94 decks
15%synergy
Sword of the Animist
17%inclusion16 decks94 decks
13%synergy
Doc Ock's Tentacles
17%inclusion9 decks54 decks
16%synergy
Mithril Coat
16%inclusion15 decks94 decks
10%synergy
Wishclaw Talisman
16%inclusion15 decks94 decks
9%synergy
Sword of Wealth and Power
15%inclusion14 decks94 decks
14%synergy
Buster Sword
14%inclusion10 decks71 decks
13%synergy
Brotherhood Regalia
13%inclusion12 decks94 decks
10%synergy
Thran Power Suit
10%inclusion9 decks94 decks
9%synergy
Strata Scythe
10%inclusion9 decks94 decks
9%synergy
Loxodon Warhammer
10%inclusion9 decks94 decks
8%synergy
Genji Glove
8.7%inclusion6 decks69 decks
8%synergy
Trailblazer's Boots
8.5%inclusion8 decks94 decks
6%synergy
Bontu's Monument
8.5%inclusion8 decks94 decks
-19%synergy
Whip of Erebos
8.5%inclusion8 decks94 decks
-2%synergy
Silver Shroud Costume
8.5%inclusion8 decks94 decks
7%synergy
Aetherflux Reservoir
8.5%inclusion8 decks94 decks
-1%synergy
Hero's Blade
8.5%inclusion8 decks94 decks
8%synergy
Grafted Exoskeleton
8.5%inclusion8 decks94 decks
7%synergy
Strength-Testing Hammer
7.4%inclusion7 decks94 decks
7%synergy
Wayfarer's Bauble
7.4%inclusion7 decks94 decks
-8%synergy
Manifold Key
7.4%inclusion7 decks94 decks
6%synergy
O-Naginata
7.4%inclusion7 decks94 decks
7%synergy
Sword of Vengeance
6.4%inclusion6 decks94 decks
5%synergy
Vorpal Sword
6.4%inclusion6 decks94 decks
3%synergy
Inquisitor's Flail
6.4%inclusion6 decks94 decks
6%synergy
Conqueror's Flail
5.3%inclusion5 decks94 decks
5%synergy
Sword of Fire and Ice
5.3%inclusion5 decks94 decks
5%synergy
Sword of Hearth and Home
5.3%inclusion5 decks94 decks
4%synergy
Winter Moon
5.3%inclusion5 decks94 decks
4%synergy
Enchantments
Unspeakable Symbol
44%inclusion41 decks94 decks
43%synergy
Necrogen Communion
30%inclusion28 decks94 decks
28%synergy
Kaya's Ghostform
22%inclusion21 decks94 decks
12%synergy
Phyresis
18%inclusion17 decks94 decks
16%synergy
No Mercy
16%inclusion15 decks94 decks
9%synergy
Contamination
16%inclusion15 decks94 decks
13%synergy
Animate Dead
13%inclusion12 decks94 decks
-5%synergy
The Meathook Massacre
12%inclusion11 decks94 decks
-6%synergy
Super State
10%inclusion7 decks67 decks
10%synergy
Dauthi Embrace
10%inclusion9 decks94 decks
8%synergy
Bitterblossom
10%inclusion9 decks94 decks
-4%synergy
Black Market
10%inclusion9 decks94 decks
-12%synergy
Haunted One
10%inclusion9 decks94 decks
7%synergy
Snake Cult Initiation
8.5%inclusion8 decks94 decks
8%synergy
Oubliette
8.5%inclusion8 decks94 decks
5%synergy
Endless Scream
8.5%inclusion8 decks94 decks
8%synergy
Glistening Oil
8.5%inclusion8 decks94 decks
8%synergy
Exquisite Blood
7.4%inclusion7 decks94 decks
-6%synergy
Phyrexian Reclamation
7.4%inclusion7 decks94 decks
-3%synergy
Infernal Darkness
7.4%inclusion7 decks94 decks
7%synergy
Bad Moon
7.4%inclusion7 decks94 decks
4%synergy
Alien Symbiosis
7.4%inclusion4 decks54 decks
7%synergy
Relic Putrescence
6.4%inclusion6 decks94 decks
6%synergy
Fungal Fortitude
6.4%inclusion6 decks94 decks
5%synergy
Leyline of the Void
6.4%inclusion6 decks94 decks
5%synergy
Demonic Embrace
5.3%inclusion5 decks94 decks
4%synergy
Shade's Form
5.3%inclusion5 decks94 decks
5%synergy
Dictate of Erebos
5.3%inclusion5 decks94 decks
-5%synergy
Planeswalkers
Liliana of the Dark Realms
40%inclusion38 decks94 decks
26%synergy
Vraska, Betrayal's Sting
36%inclusion34 decks94 decks
33%synergy
Tezzeret, Cruel Captain
7.4%inclusion5 decks68 decks
6%synergy
Utility Lands
Cabal Coffers
82%inclusion77 decks94 decks
27%synergy
Urborg, Tomb of Yawgmoth
77%inclusion72 decks94 decks
39%synergy
Rogue's Passage
52%inclusion49 decks94 decks
33%synergy
Karn's Bastion
43%inclusion40 decks94 decks
38%synergy
Urza's Saga
37%inclusion35 decks94 decks
29%synergy
Bojuka Bog
36%inclusion34 decks94 decks
-11%synergy
Cabal Stronghold
36%inclusion34 decks94 decks
1%synergy
Nykthos, Shrine to Nyx
27%inclusion25 decks94 decks
-3%synergy
The Black Gate
26%inclusion24 decks94 decks
22%synergy
Command Beacon
16%inclusion15 decks94 decks
8%synergy
Lake of the Dead
16%inclusion15 decks94 decks
11%synergy
Castle Locthwain
16%inclusion15 decks94 decks
-1%synergy
Phyrexian Tower
15%inclusion14 decks94 decks
-10%synergy
Strip Mine
14%inclusion13 decks94 decks
11%synergy
Reliquary Tower
13%inclusion12 decks94 decks
-18%synergy
Cathedral of War
13%inclusion12 decks94 decks
12%synergy
Takenuma, Abandoned Mire
13%inclusion12 decks94 decks
-3%synergy
War Room
12%inclusion11 decks94 decks
-5%synergy
Homeward Path
12%inclusion11 decks94 decks
10%synergy
Minas Morgul, Dark Fortress
10%inclusion9 decks94 decks
7%synergy
Deserted Temple
7.4%inclusion7 decks94 decks
3%synergy
Mortuary Mire
7.4%inclusion7 decks94 decks
-6%synergy
Vault of Whispers
7.4%inclusion7 decks94 decks
2%synergy
Witch's Cottage
7.4%inclusion7 decks94 decks
-17%synergy
Temple of the False God
7.4%inclusion7 decks94 decks
-1%synergy
Emergence Zone
6.4%inclusion6 decks94 decks
3%synergy
Inventors' Fair
6.4%inclusion6 decks94 decks
4%synergy
Arcane Lighthouse
5.3%inclusion5 decks94 decks
3%synergy
Wasteland
5.3%inclusion5 decks94 decks
4%synergy
Buried Ruin
5.3%inclusion5 decks94 decks
0%synergy
Crystal Vein
5.3%inclusion5 decks94 decks
3%synergy
Mana Artifacts
Sol Ring
98%inclusion92 decks94 decks
12%synergy
Arcane Signet
69%inclusion65 decks94 decks
7%synergy
The Soul Stone
42%inclusion25 decks60 decks
28%synergy
Mox Opal
41%inclusion39 decks94 decks
38%synergy
Lotus Petal
39%inclusion37 decks94 decks
32%synergy
Glistening Sphere
30%inclusion28 decks94 decks
29%synergy
Mox Diamond
29%inclusion27 decks94 decks
25%synergy
Mind Stone
27%inclusion25 decks94 decks
-3%synergy
Grim Monolith
23%inclusion22 decks94 decks
21%synergy
Fellwar Stone
23%inclusion22 decks94 decks
9%synergy
Staff of Compleation
23%inclusion22 decks94 decks
22%synergy
Throne of Eldraine
20%inclusion19 decks94 decks
10%synergy
Heraldic Banner
19%inclusion18 decks94 decks
14%synergy
Caged Sun
16%inclusion15 decks94 decks
4%synergy
Thought Vessel
16%inclusion15 decks94 decks
-11%synergy
Mox Amber
15%inclusion14 decks94 decks
11%synergy
Mox Jasper
13%inclusion11 decks85 decks
13%synergy
Charcoal Diamond
12%inclusion11 decks94 decks
-11%synergy
Extraplanar Lens
12%inclusion11 decks94 decks
7%synergy
Patchwork Banner
10%inclusion9 decks94 decks
5%synergy
Thran Dynamo
8.5%inclusion8 decks94 decks
3%synergy
Sceptre of Eternal Glory
8.5%inclusion8 decks94 decks
0%synergy
Gilded Lotus
7.4%inclusion7 decks94 decks
2%synergy
Everflowing Chalice
6.4%inclusion6 decks94 decks
0%synergy
Mox Tantalite
5.3%inclusion5 decks94 decks
5%synergy
Gauntlet of Power
5.3%inclusion5 decks94 decks
2%synergy
Lands
Swamp
95%inclusion89 decks94 decks
0%synergy
Cavern of Souls
36%inclusion34 decks94 decks
30%synergy
Malakir Rebirth
32%inclusion30 decks94 decks
9%synergy
Gemstone Caverns
27%inclusion25 decks94 decks
22%synergy
Myriad Landscape
16%inclusion15 decks94 decks
-10%synergy
Fell the Profane
15%inclusion14 decks94 decks
-4%synergy
Marsh Flats
14%inclusion13 decks94 decks
10%synergy
Mirrex
14%inclusion13 decks94 decks
13%synergy
Polluted Delta
14%inclusion13 decks94 decks
10%synergy
Bloodstained Mire
14%inclusion13 decks94 decks
10%synergy
Verdant Catacombs
13%inclusion12 decks94 decks
9%synergy
Urza's Cave
8.5%inclusion8 decks94 decks
0%synergy
Command Tower
7.4%inclusion7 decks94 decks
2%synergy
Snow-Covered Swamp
7.4%inclusion7 decks94 decks
1%synergy
Talon Gates of Madara
6.4%inclusion6 decks94 decks
5%synergy
Prismatic Vista
5.3%inclusion5 decks94 decks
3%synergy
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