Venom, King in Black (Commander) - Optimized Infect

Original Name:

Skithiryx, the Blight DragonSkithiryx, the Blight Dragon

Venom, King in Black
Rank #784
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Enchantments
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Utility Lands
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Madame Null, Power Broker
14%inclusion1 decks7 decks
13%synergy
Splinter's Technique
14%inclusion1 decks7 decks
12%synergy
Super Shredder
5.9%inclusion1 decks17 decks
4%synergy
High Synergy Cards
Plague Stinger
80%inclusion20 decks25 decks
79%synergy
Whispering Specter
68%inclusion17 decks25 decks
67%synergy
Plague Myr
64%inclusion16 decks25 decks
63%synergy
Shizo, Death's Storehouse
72%inclusion18 decks25 decks
62%synergy
Phyresis Outbreak
60%inclusion15 decks25 decks
58%synergy
Lashwrithe
60%inclusion15 decks25 decks
56%synergy
Karn's Bastion
60%inclusion15 decks25 decks
56%synergy
Howl from Beyond
56%inclusion14 decks25 decks
55%synergy
Hand of the Praetors
56%inclusion14 decks25 decks
55%synergy
Phyrexian Crusader
56%inclusion14 decks25 decks
55%synergy
Top Cards
Dark Ritual
92%inclusion23 decks25 decks
25%synergy
Jet Medallion
84%inclusion21 decks25 decks
22%synergy
Crypt Ghast
76%inclusion19 decks25 decks
28%synergy
Deadly Rollick
72%inclusion18 decks25 decks
48%synergy
Cabal Ritual
60%inclusion15 decks25 decks
42%synergy
Toxic Deluge
60%inclusion15 decks25 decks
23%synergy
Damnation
60%inclusion15 decks25 decks
39%synergy
Vraska's Fall
56%inclusion14 decks25 decks
53%synergy
Ichor Rats
56%inclusion14 decks25 decks
53%synergy
Feed the Swarm
52%inclusion13 decks25 decks
1%synergy
Game Changers
Demonic Tutor
84%inclusion21 decks25 decks
57%synergy
Vampiric Tutor
76%inclusion19 decks25 decks
55%synergy
Ancient Tomb
68%inclusion17 decks25 decks
56%synergy
Necropotence
60%inclusion15 decks25 decks
45%synergy
Mana Vault
52%inclusion13 decks25 decks
45%synergy
Chrome Mox
48%inclusion12 decks25 decks
42%synergy
Imperial Seal
44%inclusion11 decks25 decks
37%synergy
Opposition Agent
44%inclusion11 decks25 decks
34%synergy
The One Ring
44%inclusion11 decks25 decks
35%synergy
Bolas's Citadel
32%inclusion8 decks25 decks
3%synergy
Creatures
K'rrik, Son of Yawgmoth
40%inclusion10 decks25 decks
21%synergy
Dauthi Voidwalker
40%inclusion10 decks25 decks
24%synergy
Sheoldred, the Apocalypse
36%inclusion9 decks25 decks
21%synergy
Phyrexian Obliterator
36%inclusion9 decks25 decks
25%synergy
Yawgmoth, Thran Physician
32%inclusion8 decks25 decks
22%synergy
Orcish Bowmasters
32%inclusion8 decks25 decks
19%synergy
Reaper of Sheoldred
28%inclusion7 decks25 decks
27%synergy
Flensermite
28%inclusion7 decks25 decks
27%synergy
Blightbelly Rat
28%inclusion7 decks25 decks
24%synergy
Pestilent Syphoner
24%inclusion6 decks25 decks
23%synergy
Dark Confidant
24%inclusion6 decks25 decks
17%synergy
Ichorclaw Myr
24%inclusion6 decks25 decks
24%synergy
Gray Merchant of Asphodel
20%inclusion5 decks25 decks
-31%synergy
Flesh-Eater Imp
20%inclusion5 decks25 decks
19%synergy
Myr Convert
16%inclusion4 decks25 decks
15%synergy
Bilious Skulldweller
16%inclusion4 decks25 decks
15%synergy
Sheoldred, Whispering One
16%inclusion4 decks25 decks
4%synergy
Septic Rats
16%inclusion4 decks25 decks
14%synergy
Blightsteel Colossus
16%inclusion4 decks25 decks
15%synergy
Contagious Nim
12%inclusion3 decks25 decks
12%synergy
Core Prowler
12%inclusion3 decks25 decks
11%synergy
Nirkana Revenant
12%inclusion3 decks25 decks
1%synergy
Vito, Thorn of the Dusk Rose
12%inclusion3 decks25 decks
1%synergy
Corpse Cur
12%inclusion3 decks25 decks
12%synergy
Necropede
12%inclusion3 decks25 decks
12%synergy
Gwenom, Remorseless
10%inclusion2 decks20 decks
6%synergy
Phyrexian Juggernaut
8.0%inclusion2 decks25 decks
8%synergy
Solemn Simulacrum
8.0%inclusion2 decks25 decks
-14%synergy
Maha, Its Feathers Night
8.0%inclusion2 decks25 decks
4%synergy
Blackcleave Goblin
8.0%inclusion2 decks25 decks
8%synergy
Lobelia Sackville-Baggins
8.0%inclusion2 decks25 decks
7%synergy
Nightmare
8.0%inclusion2 decks25 decks
7%synergy
Bloodletter of Aclazotz
8.0%inclusion2 decks25 decks
-3%synergy
Swamp Mosquito
8.0%inclusion2 decks25 decks
8%synergy
Necroskitter
8.0%inclusion2 decks25 decks
5%synergy
Massacre Wurm
8.0%inclusion2 decks25 decks
-9%synergy
Sheoldred's Headcleaver
8.0%inclusion2 decks25 decks
8%synergy
Nimraiser Paladin
8.0%inclusion2 decks25 decks
8%synergy
Scheming Aspirant
8.0%inclusion2 decks25 decks
8%synergy
Accursed Marauder
8.0%inclusion2 decks25 decks
-13%synergy
Gulping Scraptrap
8.0%inclusion2 decks25 decks
7%synergy
Leaden Myr
8.0%inclusion2 decks25 decks
2%synergy
Bitterbloom Bearer
5.9%inclusion1 decks17 decks
0%synergy
Agent Venom
5.3%inclusion1 decks19 decks
3%synergy
Surge Conductor
5.0%inclusion1 decks20 decks
5%synergy
Instants
Imp's Mischief
44%inclusion11 decks25 decks
19%synergy
Hatred
44%inclusion11 decks25 decks
43%synergy
Go for the Throat
40%inclusion10 decks25 decks
17%synergy
Dismember
40%inclusion10 decks25 decks
30%synergy
Tainted Strike
32%inclusion8 decks25 decks
29%synergy
Sudden Spoiling
32%inclusion8 decks25 decks
23%synergy
Withering Torment
32%inclusion8 decks25 decks
0%synergy
Whisper of the Dross
28%inclusion7 decks25 decks
25%synergy
Sheoldred's Edict
24%inclusion6 decks25 decks
9%synergy
Snuff Out
24%inclusion6 decks25 decks
11%synergy
Darkness
24%inclusion6 decks25 decks
14%synergy
Infernal Grasp
24%inclusion6 decks25 decks
-1%synergy
Hero's Downfall
20%inclusion5 decks25 decks
13%synergy
Fell the Profane
20%inclusion5 decks25 decks
1%synergy
Cut Down
20%inclusion5 decks25 decks
16%synergy
Astarion's Thirst
16%inclusion4 decks25 decks
15%synergy
Culling the Weak
16%inclusion4 decks25 decks
0%synergy
Withering Boon
16%inclusion4 decks25 decks
12%synergy
Malakir Rebirth
16%inclusion4 decks25 decks
-7%synergy
Force of Despair
12%inclusion3 decks25 decks
4%synergy
Defile
12%inclusion3 decks25 decks
-25%synergy
Doom Blade
12%inclusion3 decks25 decks
5%synergy
Soul Shatter
12%inclusion3 decks25 decks
0%synergy
Slaughter Pact
12%inclusion3 decks25 decks
9%synergy
Murder
12%inclusion3 decks25 decks
2%synergy
Not Dead After All
8.0%inclusion2 decks25 decks
-3%synergy
Anoint with Affliction
8.0%inclusion2 decks25 decks
7%synergy
Grim Affliction
8.0%inclusion2 decks25 decks
6%synergy
Sugar Rush
8.0%inclusion2 decks25 decks
8%synergy
Virulent Wound
8.0%inclusion2 decks25 decks
8%synergy
Bitter Triumph
8.0%inclusion2 decks25 decks
-2%synergy
Virulent Swipe
8.0%inclusion2 decks25 decks
8%synergy
Ad Nauseam
8.0%inclusion2 decks25 decks
5%synergy
Baleful Mastery
8.0%inclusion2 decks25 decks
-1%synergy
Black Sun's Twilight
8.0%inclusion2 decks25 decks
4%synergy
Liliana's Triumph
8.0%inclusion2 decks25 decks
2%synergy
Archenemy's Charm
5.0%inclusion1 decks20 decks
-4%synergy
Sorceries
Infectious Inquiry
52%inclusion13 decks25 decks
49%synergy
Night's Whisper
52%inclusion13 decks25 decks
27%synergy
Grim Tutor
52%inclusion13 decks25 decks
40%synergy
Drown in Ichor
48%inclusion12 decks25 decks
44%synergy
Bubbling Muck
44%inclusion11 decks25 decks
28%synergy
Sign in Blood
44%inclusion11 decks25 decks
8%synergy
Crux of Fate
40%inclusion10 decks25 decks
39%synergy
Reanimate
32%inclusion8 decks25 decks
-8%synergy
Blasphemous Edict
25%inclusion6 decks24 decks
8%synergy
Caress of Phyrexia
24%inclusion6 decks25 decks
23%synergy
Diabolic Tutor
20%inclusion5 decks25 decks
6%synergy
Profane Tutor
20%inclusion5 decks25 decks
16%synergy
Torment of Hailfire
20%inclusion5 decks25 decks
5%synergy
Exsanguinate
20%inclusion5 decks25 decks
-5%synergy
Insatiable Avarice
20%inclusion5 decks25 decks
8%synergy
Vat Emergence
16%inclusion4 decks25 decks
15%synergy
Duress
16%inclusion4 decks25 decks
9%synergy
Beseech the Mirror
16%inclusion4 decks25 decks
9%synergy
Yawgmoth's Will
12%inclusion3 decks25 decks
9%synergy
Read the Bones
12%inclusion3 decks25 decks
-5%synergy
Mutilate
12%inclusion3 decks25 decks
-5%synergy
Praetor's Grasp
12%inclusion3 decks25 decks
8%synergy
Dark Petition
12%inclusion3 decks25 decks
8%synergy
Beseech the Queen
12%inclusion3 decks25 decks
6%synergy
Black Sun's Zenith
8.0%inclusion2 decks25 decks
3%synergy
Victimize
8.0%inclusion2 decks25 decks
-19%synergy
Innocent Blood
8.0%inclusion2 decks25 decks
2%synergy
Dreams of Steel and Oil
8.0%inclusion2 decks25 decks
8%synergy
Disentomb
8.0%inclusion2 decks25 decks
7%synergy
Thoughtseize
8.0%inclusion2 decks25 decks
3%synergy
Utility Artifacts
Swiftfoot Boots
52%inclusion13 decks25 decks
21%synergy
Commander's Plate
52%inclusion13 decks25 decks
46%synergy
Shadowspear
48%inclusion12 decks25 decks
44%synergy
Blackblade Reforged
48%inclusion12 decks25 decks
45%synergy
Nightmare Lash
44%inclusion11 decks25 decks
42%synergy
Lightning Greaves
44%inclusion11 decks25 decks
10%synergy
Sword of Truth and Justice
36%inclusion9 decks25 decks
35%synergy
Whispersilk Cloak
36%inclusion9 decks25 decks
30%synergy
Mithril Coat
32%inclusion8 decks25 decks
26%synergy
Contagion Engine
28%inclusion7 decks25 decks
26%synergy
Fireshrieker
28%inclusion7 decks25 decks
26%synergy
Champion's Helm
28%inclusion7 decks25 decks
26%synergy
Sensei's Divining Top
24%inclusion6 decks25 decks
16%synergy
Expedition Map
24%inclusion6 decks25 decks
12%synergy
The Darkness Crystal
24%inclusion5 decks21 decks
4%synergy
Wishclaw Talisman
20%inclusion5 decks25 decks
13%synergy
Conqueror's Flail
20%inclusion5 decks25 decks
19%synergy
Doc Ock's Tentacles
17%inclusion3 decks18 decks
16%synergy
Contagion Clasp
16%inclusion4 decks25 decks
14%synergy
Silver Shroud Costume
16%inclusion4 decks25 decks
15%synergy
Hammer of Nazahn
16%inclusion4 decks25 decks
15%synergy
Genji Glove
14%inclusion3 decks21 decks
13%synergy
Leyline Axe
13%inclusion3 decks24 decks
12%synergy
Thran Power Suit
12%inclusion3 decks25 decks
12%synergy
Trailblazer's Boots
12%inclusion3 decks25 decks
10%synergy
Cranial Plating
12%inclusion3 decks25 decks
9%synergy
Winter Moon
12%inclusion3 decks25 decks
10%synergy
Sword of Feast and Famine
12%inclusion3 decks25 decks
10%synergy
Brotherhood Regalia
12%inclusion3 decks25 decks
9%synergy
Sword of the Animist
12%inclusion3 decks25 decks
8%synergy
Black Mage's Rod
10%inclusion2 decks21 decks
9%synergy
Lavaspur Boots
8.0%inclusion2 decks25 decks
6%synergy
Sword of Hearth and Home
8.0%inclusion2 decks25 decks
7%synergy
Bontu's Monument
8.0%inclusion2 decks25 decks
-20%synergy
Sword of Wealth and Power
8.0%inclusion2 decks25 decks
7%synergy
Pact Weapon
8.0%inclusion2 decks25 decks
6%synergy
Loxodon Warhammer
8.0%inclusion2 decks25 decks
7%synergy
Isochron Scepter
8.0%inclusion2 decks25 decks
8%synergy
Sword of Vengeance
8.0%inclusion2 decks25 decks
7%synergy
Hero's Blade
8.0%inclusion2 decks25 decks
8%synergy
Basilisk Collar
8.0%inclusion2 decks25 decks
5%synergy
Enchantments
Phyrexian Arena
52%inclusion13 decks25 decks
12%synergy
Unspeakable Symbol
48%inclusion12 decks25 decks
47%synergy
Black Market Connections
40%inclusion10 decks25 decks
16%synergy
Necrogen Communion
32%inclusion8 decks25 decks
30%synergy
No Mercy
24%inclusion6 decks25 decks
17%synergy
Phyresis
20%inclusion5 decks25 decks
18%synergy
Super State
19%inclusion4 decks21 decks
19%synergy
The Meathook Massacre
16%inclusion4 decks25 decks
-1%synergy
Contamination
16%inclusion4 decks25 decks
13%synergy
Leyline of the Void
16%inclusion4 decks25 decks
14%synergy
Glistening Oil
12%inclusion3 decks25 decks
11%synergy
Phyrexian Reclamation
12%inclusion3 decks25 decks
2%synergy
Demonic Embrace
12%inclusion3 decks25 decks
11%synergy
Infernal Darkness
12%inclusion3 decks25 decks
11%synergy
Grievous Wound
8.0%inclusion2 decks25 decks
6%synergy
Haunted One
8.0%inclusion2 decks25 decks
5%synergy
Grave Pact
8.0%inclusion2 decks25 decks
-11%synergy
Exquisite Blood
8.0%inclusion2 decks25 decks
-5%synergy
Wound Reflection
8.0%inclusion2 decks25 decks
5%synergy
Kaya's Ghostform
8.0%inclusion2 decks25 decks
-2%synergy
Dauthi Embrace
8.0%inclusion2 decks25 decks
6%synergy
Snake Cult Initiation
8.0%inclusion2 decks25 decks
8%synergy
Oubliette
8.0%inclusion2 decks25 decks
5%synergy
Fungal Fortitude
8.0%inclusion2 decks25 decks
7%synergy
Heartless Summoning
8.0%inclusion2 decks25 decks
3%synergy
Bitterblossom
8.0%inclusion2 decks25 decks
-5%synergy
Planeswalkers
Liliana of the Dark Realms
52%inclusion13 decks25 decks
38%synergy
Vraska, Betrayal's Sting
40%inclusion10 decks25 decks
37%synergy
Liliana of the Veil
8.0%inclusion2 decks25 decks
1%synergy
Utility Lands
Urborg, Tomb of Yawgmoth
76%inclusion19 decks25 decks
38%synergy
Cabal Coffers
68%inclusion17 decks25 decks
13%synergy
Rogue's Passage
68%inclusion17 decks25 decks
49%synergy
Inkmoth Nexus
52%inclusion13 decks25 decks
51%synergy
Nykthos, Shrine to Nyx
40%inclusion10 decks25 decks
10%synergy
Cabal Stronghold
36%inclusion9 decks25 decks
1%synergy
Urza's Saga
36%inclusion9 decks25 decks
28%synergy
Bojuka Bog
32%inclusion8 decks25 decks
-15%synergy
Lake of the Dead
28%inclusion7 decks25 decks
23%synergy
Strip Mine
24%inclusion6 decks25 decks
21%synergy
Reliquary Tower
20%inclusion5 decks25 decks
-10%synergy
The Black Gate
16%inclusion4 decks25 decks
13%synergy
Cathedral of War
16%inclusion4 decks25 decks
16%synergy
Deserted Temple
16%inclusion4 decks25 decks
12%synergy
Takenuma, Abandoned Mire
16%inclusion4 decks25 decks
0%synergy
Homeward Path
16%inclusion4 decks25 decks
14%synergy
Temple of the False God
16%inclusion4 decks25 decks
8%synergy
Vault of Whispers
12%inclusion3 decks25 decks
7%synergy
Arcane Lighthouse
12%inclusion3 decks25 decks
10%synergy
Command Beacon
12%inclusion3 decks25 decks
4%synergy
Minas Morgul, Dark Fortress
12%inclusion3 decks25 decks
9%synergy
Wasteland
8.0%inclusion2 decks25 decks
7%synergy
Phyrexian Tower
8.0%inclusion2 decks25 decks
-17%synergy
Maze of Ith
8.0%inclusion2 decks25 decks
5%synergy
War Room
8.0%inclusion2 decks25 decks
-8%synergy
Emergence Zone
8.0%inclusion2 decks25 decks
5%synergy
Thespian's Stage
8.0%inclusion2 decks25 decks
3%synergy
Castle Locthwain
8.0%inclusion2 decks25 decks
-9%synergy
Mana Artifacts
Sol Ring
96%inclusion24 decks25 decks
10%synergy
Arcane Signet
56%inclusion14 decks25 decks
-6%synergy
Lotus Petal
44%inclusion11 decks25 decks
37%synergy
The Soul Stone
40%inclusion8 decks20 decks
26%synergy
Mox Opal
36%inclusion9 decks25 decks
33%synergy
Staff of Compleation
28%inclusion7 decks25 decks
26%synergy
Glistening Sphere
28%inclusion7 decks25 decks
27%synergy
Mox Amber
28%inclusion7 decks25 decks
24%synergy
Fellwar Stone
28%inclusion7 decks25 decks
14%synergy
Mind Stone
24%inclusion6 decks25 decks
-5%synergy
Mox Diamond
20%inclusion5 decks25 decks
16%synergy
Heraldic Banner
16%inclusion4 decks25 decks
11%synergy
Gilded Lotus
16%inclusion4 decks25 decks
11%synergy
Mox Jasper
13%inclusion3 decks23 decks
13%synergy
Caged Sun
12%inclusion3 decks25 decks
1%synergy
Charcoal Diamond
12%inclusion3 decks25 decks
-10%synergy
Throne of Eldraine
12%inclusion3 decks25 decks
2%synergy
Thought Vessel
12%inclusion3 decks25 decks
-14%synergy
Extraplanar Lens
12%inclusion3 decks25 decks
7%synergy
Grim Monolith
8.0%inclusion2 decks25 decks
5%synergy
Lands
Swamp
96%inclusion24 decks25 decks
1%synergy
Cavern of Souls
48%inclusion12 decks25 decks
41%synergy
Verdant Catacombs
32%inclusion8 decks25 decks
29%synergy
Bloodstained Mire
32%inclusion8 decks25 decks
28%synergy
Marsh Flats
28%inclusion7 decks25 decks
25%synergy
Polluted Delta
28%inclusion7 decks25 decks
24%synergy
Fell the Profane
20%inclusion5 decks25 decks
1%synergy
Gemstone Caverns
20%inclusion5 decks25 decks
16%synergy
Malakir Rebirth
16%inclusion4 decks25 decks
-7%synergy
Command Tower
12%inclusion3 decks25 decks
6%synergy
Fabled Passage
12%inclusion3 decks25 decks
10%synergy
Myriad Landscape
12%inclusion3 decks25 decks
-14%synergy
Mirrex
12%inclusion3 decks25 decks
11%synergy
Prismatic Vista
8.0%inclusion2 decks25 decks
6%synergy
The Mycosynth Gardens
8.0%inclusion2 decks25 decks
7%synergy
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