Venom, King in Black (Commander) - Infect

Original Name:

Skithiryx, the Blight DragonSkithiryx, the Blight Dragon

Venom, King in Black
Rank #787
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Enchantments
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Utility Lands
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Emeritus of Woe
10%inclusion1 decks10 decks
6%synergy
Madame Null, Power Broker
5.3%inclusion4 decks75 decks
4%synergy
Shredder's Technique
5.1%inclusion3 decks59 decks
1%synergy
Splinter's Technique
4.0%inclusion3 decks75 decks
2%synergy
Ninja Teen
2.7%inclusion2 decks74 decks
1%synergy
High Synergy Cards
Plague Stinger
80%inclusion495 decks618 decks
79%synergy
Plague Myr
78%inclusion483 decks618 decks
77%synergy
Ichor Rats
78%inclusion483 decks618 decks
75%synergy
Hand of the Praetors
75%inclusion465 decks618 decks
74%synergy
Infectious Inquiry
76%inclusion467 decks618 decks
73%synergy
Vraska's Fall
70%inclusion433 decks618 decks
67%synergy
Karn's Bastion
70%inclusion432 decks618 decks
66%synergy
Whispering Specter
67%inclusion411 decks618 decks
66%synergy
Phyrexian Crusader
65%inclusion402 decks618 decks
64%synergy
Drown in Ichor
66%inclusion405 decks618 decks
62%synergy
Top Cards
Dark Ritual
78%inclusion484 decks618 decks
12%synergy
Jet Medallion
65%inclusion403 decks618 decks
4%synergy
Lashwrithe
64%inclusion394 decks618 decks
60%synergy
Swiftfoot Boots
63%inclusion387 decks618 decks
31%synergy
Crypt Ghast
62%inclusion381 decks618 decks
14%synergy
Blightbelly Rat
62%inclusion381 decks618 decks
58%synergy
Phyresis Outbreak
61%inclusion378 decks618 decks
59%synergy
Phyrexian Arena
60%inclusion370 decks618 decks
20%synergy
Sign in Blood
56%inclusion343 decks618 decks
20%synergy
Nightmare Lash
54%inclusion336 decks618 decks
52%synergy
Game Changers
Demonic Tutor
41%inclusion254 decks618 decks
14%synergy
Vampiric Tutor
31%inclusion193 decks618 decks
10%synergy
Necropotence
22%inclusion136 decks618 decks
7%synergy
Ancient Tomb
20%inclusion126 decks618 decks
9%synergy
Bolas's Citadel
16%inclusion101 decks618 decks
-12%synergy
Mana Vault
15%inclusion92 decks618 decks
8%synergy
Opposition Agent
12%inclusion74 decks618 decks
2%synergy
Chrome Mox
11%inclusion65 decks618 decks
5%synergy
The One Ring
10%inclusion63 decks618 decks
1%synergy
Imperial Seal
9.1%inclusion56 decks618 decks
2%synergy
Creatures
Reaper of Sheoldred
53%inclusion329 decks618 decks
53%synergy
Flensermite
45%inclusion278 decks618 decks
44%synergy
Ichorclaw Myr
45%inclusion278 decks618 decks
44%synergy
Bilious Skulldweller
43%inclusion266 decks618 decks
42%synergy
Core Prowler
42%inclusion262 decks618 decks
42%synergy
Corpse Cur
41%inclusion253 decks618 decks
41%synergy
Pestilent Syphoner
37%inclusion229 decks618 decks
36%synergy
Flesh-Eater Imp
36%inclusion225 decks618 decks
36%synergy
Phyrexian Obliterator
34%inclusion212 decks618 decks
23%synergy
Septic Rats
34%inclusion212 decks618 decks
32%synergy
K'rrik, Son of Yawgmoth
32%inclusion196 decks618 decks
13%synergy
Necropede
28%inclusion172 decks618 decks
27%synergy
Myr Convert
26%inclusion158 decks618 decks
25%synergy
Yawgmoth, Thran Physician
24%inclusion151 decks618 decks
14%synergy
Blightsteel Colossus
23%inclusion143 decks618 decks
22%synergy
Gray Merchant of Asphodel
22%inclusion134 decks618 decks
-29%synergy
Solemn Simulacrum
21%inclusion130 decks618 decks
-1%synergy
Leaden Myr
21%inclusion128 decks618 decks
15%synergy
Contagious Nim
20%inclusion123 decks618 decks
20%synergy
Gulping Scraptrap
19%inclusion118 decks618 decks
19%synergy
Blackcleave Goblin
18%inclusion110 decks618 decks
18%synergy
Phyrexian Juggernaut
15%inclusion93 decks618 decks
15%synergy
Magus of the Coffers
15%inclusion91 decks618 decks
8%synergy
Dauthi Voidwalker
14%inclusion86 decks618 decks
-2%synergy
Defiler of Flesh
14%inclusion84 decks618 decks
10%synergy
Necroskitter
13%inclusion83 decks618 decks
10%synergy
Massacre Girl, Known Killer
13%inclusion81 decks618 decks
9%synergy
Phyrexian Vatmother
13%inclusion80 decks618 decks
13%synergy
Dread Presence
13%inclusion78 decks618 decks
-2%synergy
Toxic Nim
12%inclusion77 decks618 decks
12%synergy
Sheoldred, Whispering One
12%inclusion77 decks618 decks
1%synergy
Sheoldred's Headcleaver
11%inclusion71 decks618 decks
11%synergy
Filth
11%inclusion70 decks618 decks
9%synergy
Dark Confidant
10%inclusion64 decks618 decks
3%synergy
Grafted Butcher
10%inclusion64 decks618 decks
10%synergy
Silent Arbiter
10%inclusion61 decks618 decks
9%synergy
Nirkana Revenant
9.4%inclusion58 decks618 decks
-2%synergy
Burnished Hart
9.2%inclusion57 decks618 decks
2%synergy
Phyrexian Digester
8.9%inclusion55 decks618 decks
9%synergy
Sheoldred, the Apocalypse
8.7%inclusion54 decks618 decks
-6%synergy
Vector Asp
8.6%inclusion53 decks618 decks
8%synergy
Maha, Its Feathers Night
7.6%inclusion39 decks511 decks
3%synergy
Brass Squire
7.6%inclusion47 decks618 decks
7%synergy
Nimraiser Paladin
7.6%inclusion47 decks618 decks
7%synergy
Gwenom, Remorseless
7.5%inclusion12 decks160 decks
4%synergy
Swamp Mosquito
7.4%inclusion46 decks618 decks
7%synergy
Massacre Wurm
7.4%inclusion46 decks618 decks
-10%synergy
Surge Conductor
7.1%inclusion12 decks168 decks
7%synergy
Orcish Bowmasters
6.8%inclusion42 decks618 decks
-6%synergy
Scourge Servant
6.5%inclusion40 decks618 decks
6%synergy
Instants
Howl from Beyond
49%inclusion302 decks618 decks
48%synergy
Whisper of the Dross
46%inclusion287 decks618 decks
44%synergy
Defile
45%inclusion277 decks618 decks
8%synergy
Go for the Throat
40%inclusion248 decks618 decks
17%synergy
Tainted Strike
38%inclusion232 decks618 decks
35%synergy
Grim Affliction
37%inclusion228 decks618 decks
35%synergy
Deadly Rollick
32%inclusion197 decks618 decks
8%synergy
Infernal Grasp
32%inclusion195 decks618 decks
6%synergy
Withering Torment
29%inclusion127 decks435 decks
-2%synergy
Imp's Mischief
28%inclusion170 decks618 decks
3%synergy
Cabal Ritual
28%inclusion170 decks618 decks
9%synergy
Dismember
28%inclusion170 decks618 decks
17%synergy
Sugar Rush
22%inclusion133 decks618 decks
21%synergy
Supernatural Stamina
20%inclusion124 decks618 decks
13%synergy
Hatred
20%inclusion122 decks618 decks
19%synergy
Malakir Rebirth
19%inclusion117 decks618 decks
-4%synergy
Consuming Corruption
18%inclusion101 decks561 decks
2%synergy
Astarion's Thirst
18%inclusion111 decks618 decks
17%synergy
Snuff Out
18%inclusion111 decks618 decks
5%synergy
Virulent Wound
18%inclusion110 decks618 decks
17%synergy
Sudden Spoiling
17%inclusion105 decks618 decks
8%synergy
Hero's Downfall
16%inclusion100 decks618 decks
9%synergy
Archenemy's Charm
15%inclusion25 decks168 decks
6%synergy
Doom Blade
14%inclusion88 decks618 decks
7%synergy
Fell the Profane
14%inclusion79 decks567 decks
-5%synergy
Force of Despair
13%inclusion79 decks618 decks
5%synergy
Anoint with Affliction
12%inclusion77 decks618 decks
12%synergy
Unlikely Aid
12%inclusion76 decks618 decks
12%synergy
Murder
12%inclusion72 decks618 decks
1%synergy
Baleful Mastery
11%inclusion71 decks618 decks
3%synergy
Darkness
11%inclusion67 decks618 decks
1%synergy
Withering Boon
10%inclusion63 decks618 decks
6%synergy
Sheoldred's Edict
10%inclusion61 decks618 decks
-5%synergy
Undying Malice
8.6%inclusion53 decks618 decks
-1%synergy
Bitter Triumph
7.9%inclusion49 decks618 decks
-2%synergy
Tragic Slip
7.8%inclusion48 decks618 decks
-12%synergy
Rush of Vitality
7.3%inclusion45 decks618 decks
7%synergy
Undying Evil
7.1%inclusion44 decks618 decks
4%synergy
Culling the Weak
7.1%inclusion44 decks618 decks
-9%synergy
Cut Down
7.1%inclusion44 decks618 decks
3%synergy
Soul Shatter
6.8%inclusion42 decks618 decks
-5%synergy
Not Dead After All
6.6%inclusion41 decks618 decks
-5%synergy
Unnatural Endurance
6.3%inclusion39 decks618 decks
6%synergy
Slaughter Pact
5.5%inclusion34 decks618 decks
3%synergy
Sorceries
Feed the Swarm
54%inclusion334 decks618 decks
4%synergy
Night's Whisper
47%inclusion292 decks618 decks
23%synergy
Crux of Fate
41%inclusion256 decks618 decks
40%synergy
Toxic Deluge
40%inclusion247 decks618 decks
3%synergy
Caress of Phyrexia
37%inclusion229 decks618 decks
36%synergy
Bubbling Muck
32%inclusion195 decks618 decks
16%synergy
Read the Bones
31%inclusion194 decks618 decks
14%synergy
Damnation
28%inclusion171 decks618 decks
7%synergy
Reanimate
26%inclusion158 decks618 decks
-14%synergy
Vat Emergence
25%inclusion155 decks618 decks
24%synergy
Diabolic Tutor
21%inclusion132 decks618 decks
7%synergy
Spread the Sickness
18%inclusion112 decks618 decks
17%synergy
Insatiable Avarice
18%inclusion112 decks618 decks
6%synergy
Mutilate
18%inclusion109 decks618 decks
0%synergy
Grim Tutor
17%inclusion104 decks618 decks
5%synergy
Exsanguinate
13%inclusion79 decks618 decks
-12%synergy
Geth's Summons
12%inclusion76 decks618 decks
12%synergy
Black Sun's Zenith
12%inclusion75 decks618 decks
7%synergy
Blasphemous Edict
12%inclusion43 decks362 decks
-5%synergy
Feed the Infection
9.4%inclusion58 decks618 decks
9%synergy
Beseech the Queen
7.4%inclusion46 decks618 decks
1%synergy
Profane Tutor
6.6%inclusion41 decks618 decks
2%synergy
Torment of Hailfire
6.3%inclusion39 decks618 decks
-9%synergy
In Garruk's Wake
6.3%inclusion39 decks618 decks
2%synergy
Syphon Mind
6.1%inclusion38 decks618 decks
-6%synergy
Fell
5.9%inclusion30 decks511 decks
2%synergy
Praetor's Grasp
5.8%inclusion36 decks618 decks
2%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion324 decks618 decks
50%synergy
Lightning Greaves
51%inclusion318 decks618 decks
18%synergy
Fireshrieker
45%inclusion276 decks618 decks
43%synergy
Contagion Clasp
43%inclusion265 decks618 decks
41%synergy
Whispersilk Cloak
40%inclusion250 decks618 decks
34%synergy
Contagion Engine
37%inclusion230 decks618 decks
35%synergy
Sword of Truth and Justice
37%inclusion230 decks618 decks
36%synergy
Commander's Plate
36%inclusion222 decks618 decks
30%synergy
Shadowspear
28%inclusion174 decks618 decks
24%synergy
The Darkness Crystal
23%inclusion43 decks187 decks
3%synergy
Champion's Helm
22%inclusion133 decks618 decks
19%synergy
Leyline Axe
21%inclusion78 decks364 decks
20%synergy
Hero's Blade
19%inclusion120 decks618 decks
19%synergy
Trailblazer's Boots
19%inclusion119 decks618 decks
17%synergy
Sword of the Animist
18%inclusion111 decks618 decks
14%synergy
Brotherhood Regalia
17%inclusion90 decks533 decks
14%synergy
Throne of Geth
15%inclusion92 decks618 decks
15%synergy
Cranial Plating
14%inclusion89 decks618 decks
11%synergy
Mithril Coat
14%inclusion88 decks618 decks
9%synergy
Sword of Feast and Famine
14%inclusion88 decks618 decks
13%synergy
Wayfarer's Bauble
14%inclusion85 decks618 decks
-2%synergy
Expedition Map
14%inclusion84 decks618 decks
2%synergy
Pact Weapon
13%inclusion83 decks618 decks
11%synergy
Genji Glove
13%inclusion24 decks180 decks
12%synergy
Grafted Exoskeleton
11%inclusion68 decks618 decks
10%synergy
Inquisitor's Flail
11%inclusion65 decks618 decks
10%synergy
Strata Scythe
10%inclusion64 decks618 decks
10%synergy
Sword of Vengeance
10%inclusion59 decks618 decks
9%synergy
Loxodon Warhammer
10%inclusion59 decks618 decks
8%synergy
Hammer of Nazahn
9.4%inclusion58 decks618 decks
9%synergy
Basilisk Collar
8.7%inclusion54 decks618 decks
6%synergy
Doc Ock's Tentacles
8.7%inclusion13 decks149 decks
9%synergy
Pip-Boy 3000
8.6%inclusion53 decks618 decks
8%synergy
Helm of the Host
8.6%inclusion53 decks618 decks
7%synergy
Darksteel Plate
8.4%inclusion52 decks618 decks
7%synergy
Prowler's Helm
8.1%inclusion50 decks618 decks
7%synergy
Bontu's Monument
8.1%inclusion50 decks618 decks
-20%synergy
Vorpal Sword
7.9%inclusion49 decks618 decks
4%synergy
Sword of Wealth and Power
7.9%inclusion49 decks618 decks
7%synergy
Grafted Wargear
7.8%inclusion48 decks618 decks
8%synergy
Sensei's Divining Top
7.0%inclusion43 decks618 decks
-1%synergy
Buster Sword
6.5%inclusion12 decks184 decks
6%synergy
Whip of Erebos
6.5%inclusion40 decks618 decks
-4%synergy
O-Naginata
6.5%inclusion40 decks618 decks
6%synergy
Sword of Fire and Ice
5.7%inclusion35 decks618 decks
5%synergy
Manifold Key
5.7%inclusion35 decks618 decks
4%synergy
Decimator Web
5.3%inclusion33 decks618 decks
5%synergy
Prosthetic Injector
5.2%inclusion32 decks618 decks
5%synergy
Enchantments
Necrogen Communion
49%inclusion304 decks618 decks
47%synergy
Unspeakable Symbol
38%inclusion236 decks618 decks
37%synergy
Kaya's Ghostform
30%inclusion184 decks618 decks
20%synergy
Black Market Connections
23%inclusion141 decks618 decks
-1%synergy
Bad Moon
20%inclusion126 decks618 decks
17%synergy
Fungal Fortitude
18%inclusion109 decks618 decks
16%synergy
Phyresis
16%inclusion99 decks618 decks
14%synergy
No Mercy
16%inclusion96 decks618 decks
8%synergy
Relic Putrescence
14%inclusion85 decks618 decks
13%synergy
Endless Scream
13%inclusion81 decks618 decks
13%synergy
Dauthi Embrace
11%inclusion71 decks618 decks
10%synergy
Shade's Form
9.4%inclusion58 decks618 decks
9%synergy
Snake Cult Initiation
9.1%inclusion56 decks618 decks
9%synergy
Super State
7.6%inclusion13 decks170 decks
7%synergy
Animate Dead
7.4%inclusion46 decks618 decks
-10%synergy
Glistening Oil
6.3%inclusion39 decks618 decks
6%synergy
Black Market
6.0%inclusion37 decks618 decks
-15%synergy
Greed
5.7%inclusion35 decks618 decks
-1%synergy
Phyrexian Reclamation
5.2%inclusion32 decks618 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion286 decks618 decks
44%synergy
Liliana of the Dark Realms
30%inclusion185 decks618 decks
16%synergy
Utility Lands
Rogue's Passage
66%inclusion409 decks618 decks
47%synergy
Cabal Coffers
62%inclusion383 decks618 decks
7%synergy
Bojuka Bog
48%inclusion297 decks618 decks
1%synergy
Urborg, Tomb of Yawgmoth
46%inclusion285 decks618 decks
9%synergy
Shizo, Death's Storehouse
44%inclusion274 decks618 decks
34%synergy
Inkmoth Nexus
41%inclusion254 decks618 decks
40%synergy
Cabal Stronghold
38%inclusion233 decks618 decks
3%synergy
Nykthos, Shrine to Nyx
25%inclusion154 decks618 decks
-5%synergy
Cathedral of War
19%inclusion120 decks618 decks
19%synergy
The Black Gate
18%inclusion114 decks618 decks
15%synergy
Castle Locthwain
17%inclusion106 decks618 decks
0%synergy
Command Beacon
16%inclusion99 decks618 decks
8%synergy
War Room
15%inclusion95 decks618 decks
-1%synergy
Reliquary Tower
15%inclusion94 decks618 decks
-15%synergy
Witch's Cottage
14%inclusion84 decks618 decks
-11%synergy
Urza's Saga
11%inclusion69 decks618 decks
3%synergy
Mortuary Mire
11%inclusion67 decks618 decks
-2%synergy
Minas Morgul, Dark Fortress
11%inclusion66 decks618 decks
8%synergy
Temple of the False God
10%inclusion59 decks618 decks
2%synergy
Lake of the Dead
8.4%inclusion52 decks618 decks
3%synergy
Takenuma, Abandoned Mire
7.8%inclusion48 decks618 decks
-8%synergy
Barren Moor
7.4%inclusion46 decks618 decks
-2%synergy
Strip Mine
7.4%inclusion46 decks618 decks
5%synergy
Maze of Ith
6.1%inclusion38 decks618 decks
3%synergy
Buried Ruin
6.0%inclusion37 decks618 decks
1%synergy
Vault of Whispers
5.8%inclusion36 decks618 decks
1%synergy
Phyrexian Tower
5.5%inclusion34 decks618 decks
-20%synergy
Thespian's Stage
5.5%inclusion34 decks618 decks
0%synergy
Spymaster's Vault
5.1%inclusion29 decks567 decks
-4%synergy
Mana Artifacts
Sol Ring
90%inclusion559 decks618 decks
5%synergy
Arcane Signet
65%inclusion403 decks618 decks
3%synergy
Glistening Sphere
45%inclusion277 decks618 decks
44%synergy
Mind Stone
33%inclusion206 decks618 decks
4%synergy
Charcoal Diamond
32%inclusion200 decks618 decks
10%synergy
Staff of Compleation
28%inclusion174 decks618 decks
26%synergy
Heraldic Banner
18%inclusion112 decks618 decks
13%synergy
Thought Vessel
17%inclusion103 decks618 decks
-9%synergy
Caged Sun
16%inclusion100 decks618 decks
5%synergy
The Soul Stone
16%inclusion26 decks163 decks
2%synergy
Fellwar Stone
15%inclusion94 decks618 decks
1%synergy
Lotus Petal
13%inclusion83 decks618 decks
6%synergy
Throne of Eldraine
11%inclusion67 decks618 decks
1%synergy
Mox Opal
10%inclusion62 decks618 decks
7%synergy
Everflowing Chalice
10%inclusion61 decks618 decks
4%synergy
Commander's Sphere
10%inclusion61 decks618 decks
1%synergy
Thran Dynamo
8.6%inclusion53 decks618 decks
3%synergy
Worn Powerstone
6.1%inclusion38 decks618 decks
2%synergy
Jeweled Lotus
6.0%inclusion37 decks618 decks
5%synergy
Gilded Lotus
6.0%inclusion37 decks618 decks
1%synergy
Sceptre of Eternal Glory
5.7%inclusion35 decks618 decks
-3%synergy
Phyrexian Atlas
5.3%inclusion33 decks618 decks
5%synergy
Extraplanar Lens
5.2%inclusion32 decks618 decks
0%synergy
Mox Amber
5.0%inclusion31 decks618 decks
1%synergy
Lands
Swamp
95%inclusion588 decks618 decks
0%synergy
Myriad Landscape
26%inclusion158 decks618 decks
0%synergy
Malakir Rebirth
19%inclusion117 decks618 decks
-4%synergy
Cavern of Souls
16%inclusion97 decks618 decks
9%synergy
Mirrex
15%inclusion95 decks618 decks
15%synergy
Fell the Profane
14%inclusion79 decks567 decks
-5%synergy
Opal Palace
7.8%inclusion48 decks618 decks
7%synergy
The Seedcore
7.6%inclusion47 decks618 decks
7%synergy
Urza's Cave
7.5%inclusion45 decks598 decks
-1%synergy
Polluted Delta
5.7%inclusion35 decks618 decks
2%synergy
Bloodstained Mire
5.7%inclusion35 decks618 decks
2%synergy
Verdant Catacombs
5.5%inclusion34 decks618 decks
2%synergy
Snow-Covered Swamp
5.3%inclusion33 decks618 decks
-1%synergy
Marsh Flats
5.2%inclusion32 decks618 decks
2%synergy
Command Tower
5.0%inclusion31 decks618 decks
-1%synergy
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