Venom, King in Black (Commander) - Infect

Original Name:

Skithiryx, the Blight DragonSkithiryx, the Blight Dragon

Venom, King in Black
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Sorceries
Utility Artifacts
Enchantments
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Utility Lands
Mana Artifacts
Lands
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Bender's Waterskin
2.7%inclusion3 decks111 decks
2%synergy
Bitterbloom Bearer
2.3%inclusion2 decks88 decks
0%synergy
Swampsnare Trap
1.6%inclusion1 decks61 decks
1%synergy
Koh, the Face Stealer
1.6%inclusion1 decks61 decks
0%synergy
Realm of Koh
1.6%inclusion1 decks61 decks
-2%synergy
High Synergy Cards
Plague Stinger
81%inclusion580 decks714 decks
80%synergy
Plague Myr
79%inclusion562 decks714 decks
77%synergy
Hand of the Praetors
77%inclusion547 decks714 decks
76%synergy
Ichor Rats
79%inclusion562 decks714 decks
76%synergy
Infectious Inquiry
76%inclusion545 decks714 decks
73%synergy
Vraska's Fall
71%inclusion506 decks714 decks
67%synergy
Whispering Specter
68%inclusion484 decks714 decks
67%synergy
Phyrexian Crusader
66%inclusion469 decks714 decks
65%synergy
Karn's Bastion
69%inclusion491 decks714 decks
65%synergy
Drown in Ichor
67%inclusion476 decks714 decks
62%synergy
Top Cards
Dark Ritual
79%inclusion564 decks714 decks
13%synergy
Lashwrithe
65%inclusion462 decks714 decks
61%synergy
Swiftfoot Boots
64%inclusion459 decks714 decks
33%synergy
Jet Medallion
62%inclusion445 decks714 decks
2%synergy
Phyrexian Arena
62%inclusion443 decks714 decks
22%synergy
Blightbelly Rat
62%inclusion440 decks714 decks
58%synergy
Phyresis Outbreak
61%inclusion434 decks714 decks
59%synergy
Crypt Ghast
60%inclusion431 decks714 decks
12%synergy
Sign in Blood
58%inclusion413 decks714 decks
22%synergy
Nightmare Lash
58%inclusion411 decks714 decks
55%synergy
Game Changers
Demonic Tutor
42%inclusion298 decks714 decks
14%synergy
Vampiric Tutor
31%inclusion219 decks714 decks
9%synergy
Necropotence
22%inclusion156 decks714 decks
7%synergy
Ancient Tomb
21%inclusion149 decks714 decks
9%synergy
Bolas's Citadel
16%inclusion113 decks714 decks
-13%synergy
Mana Vault
15%inclusion108 decks714 decks
8%synergy
Opposition Agent
13%inclusion91 decks714 decks
3%synergy
The One Ring
11%inclusion80 decks714 decks
2%synergy
Chrome Mox
11%inclusion77 decks714 decks
5%synergy
Imperial Seal
9.1%inclusion65 decks714 decks
2%synergy
Creatures
Reaper of Sheoldred
55%inclusion390 decks714 decks
54%synergy
Ichorclaw Myr
48%inclusion340 decks714 decks
47%synergy
Flensermite
46%inclusion328 decks714 decks
45%synergy
Core Prowler
45%inclusion323 decks714 decks
45%synergy
Corpse Cur
44%inclusion314 decks714 decks
44%synergy
Bilious Skulldweller
44%inclusion312 decks714 decks
43%synergy
Flesh-Eater Imp
39%inclusion280 decks714 decks
38%synergy
Pestilent Syphoner
38%inclusion270 decks714 decks
37%synergy
Septic Rats
37%inclusion263 decks714 decks
35%synergy
Phyrexian Obliterator
34%inclusion244 decks714 decks
23%synergy
K'rrik, Son of Yawgmoth
31%inclusion219 decks714 decks
12%synergy
Necropede
29%inclusion206 decks714 decks
28%synergy
Myr Convert
27%inclusion196 decks714 decks
27%synergy
Yawgmoth, Thran Physician
24%inclusion172 decks714 decks
14%synergy
Solemn Simulacrum
23%inclusion161 decks714 decks
-1%synergy
Blightsteel Colossus
22%inclusion158 decks714 decks
21%synergy
Gray Merchant of Asphodel
22%inclusion157 decks714 decks
-30%synergy
Contagious Nim
22%inclusion155 decks714 decks
21%synergy
Leaden Myr
20%inclusion145 decks714 decks
14%synergy
Gulping Scraptrap
19%inclusion135 decks714 decks
18%synergy
Blackcleave Goblin
18%inclusion130 decks714 decks
18%synergy
Phyrexian Juggernaut
16%inclusion116 decks714 decks
16%synergy
Massacre Girl, Known Killer
15%inclusion102 decks699 decks
11%synergy
Magus of the Coffers
15%inclusion104 decks714 decks
7%synergy
Defiler of Flesh
14%inclusion103 decks714 decks
10%synergy
Necroskitter
14%inclusion100 decks714 decks
11%synergy
Dauthi Voidwalker
14%inclusion97 decks714 decks
-2%synergy
Sheoldred, Whispering One
13%inclusion94 decks714 decks
1%synergy
Phyrexian Vatmother
13%inclusion94 decks714 decks
13%synergy
Toxic Nim
13%inclusion92 decks714 decks
13%synergy
Dread Presence
13%inclusion90 decks714 decks
-2%synergy
Grafted Butcher
12%inclusion86 decks714 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion83 decks714 decks
11%synergy
Filth
11%inclusion82 decks714 decks
9%synergy
Dark Confidant
11%inclusion77 decks714 decks
4%synergy
Silent Arbiter
10%inclusion69 decks714 decks
8%synergy
Nirkana Revenant
9.2%inclusion66 decks714 decks
-2%synergy
Phyrexian Digester
9.2%inclusion66 decks714 decks
9%synergy
Burnished Hart
9.0%inclusion64 decks714 decks
1%synergy
Sheoldred, the Apocalypse
8.7%inclusion62 decks714 decks
-6%synergy
Maha, Its Feathers Night
8.5%inclusion41 decks483 decks
4%synergy
Nimraiser Paladin
8.4%inclusion60 decks714 decks
8%synergy
Orcish Bowmasters
8.0%inclusion57 decks714 decks
-6%synergy
Vector Asp
7.8%inclusion56 decks714 decks
8%synergy
Massacre Wurm
7.0%inclusion50 decks714 decks
-10%synergy
Swamp Mosquito
6.9%inclusion49 decks714 decks
7%synergy
Scourge Servant
6.9%inclusion49 decks714 decks
7%synergy
Murderous Rider
6.6%inclusion47 decks714 decks
0%synergy
Paragon of Open Graves
6.4%inclusion46 decks714 decks
6%synergy
Brass Squire
6.4%inclusion46 decks714 decks
6%synergy
Instants
Howl from Beyond
53%inclusion378 decks714 decks
52%synergy
Whisper of the Dross
47%inclusion338 decks714 decks
44%synergy
Defile
44%inclusion316 decks714 decks
7%synergy
Go for the Throat
40%inclusion288 decks714 decks
17%synergy
Tainted Strike
39%inclusion278 decks714 decks
36%synergy
Grim Affliction
37%inclusion266 decks714 decks
35%synergy
Deadly Rollick
32%inclusion232 decks714 decks
9%synergy
Infernal Grasp
32%inclusion226 decks714 decks
6%synergy
Withering Torment
29%inclusion118 decks405 decks
-2%synergy
Dismember
29%inclusion205 decks714 decks
18%synergy
Cabal Ritual
27%inclusion193 decks714 decks
9%synergy
Imp's Mischief
27%inclusion190 decks714 decks
3%synergy
Sugar Rush
25%inclusion176 decks714 decks
24%synergy
Supernatural Stamina
23%inclusion163 decks714 decks
15%synergy
Hatred
20%inclusion146 decks714 decks
19%synergy
Astarion's Thirst
19%inclusion136 decks714 decks
18%synergy
Virulent Wound
18%inclusion132 decks714 decks
18%synergy
Sudden Spoiling
18%inclusion130 decks714 decks
9%synergy
Consuming Corruption
18%inclusion94 decks534 decks
1%synergy
Malakir Rebirth
17%inclusion124 decks714 decks
-5%synergy
Snuff Out
17%inclusion119 decks714 decks
4%synergy
Archenemy's Charm
16%inclusion20 decks123 decks
7%synergy
Hero's Downfall
16%inclusion115 decks714 decks
9%synergy
Doom Blade
15%inclusion109 decks714 decks
8%synergy
Fell the Profane
14%inclusion75 decks540 decks
-5%synergy
Force of Despair
13%inclusion96 decks714 decks
6%synergy
Unlikely Aid
13%inclusion94 decks714 decks
13%synergy
Anoint with Affliction
12%inclusion89 decks714 decks
12%synergy
Murder
12%inclusion88 decks714 decks
2%synergy
Baleful Mastery
12%inclusion83 decks714 decks
2%synergy
Withering Boon
10%inclusion73 decks714 decks
6%synergy
Sheoldred's Edict
10%inclusion69 decks714 decks
-5%synergy
Darkness
10%inclusion68 decks714 decks
0%synergy
Undying Malice
8.4%inclusion60 decks714 decks
-1%synergy
Rush of Vitality
8.3%inclusion59 decks714 decks
7%synergy
Bitter Triumph
8.1%inclusion58 decks714 decks
-2%synergy
Tragic Slip
8.1%inclusion58 decks714 decks
-12%synergy
Culling the Weak
8.0%inclusion57 decks714 decks
-7%synergy
Not Dead After All
7.6%inclusion54 decks714 decks
-4%synergy
Cut Down
7.3%inclusion52 decks714 decks
3%synergy
Undying Evil
7.3%inclusion52 decks714 decks
4%synergy
Soul Shatter
6.7%inclusion48 decks714 decks
-6%synergy
Unnatural Endurance
6.4%inclusion46 decks714 decks
6%synergy
Slaughter Pact
6.2%inclusion44 decks714 decks
3%synergy
Overkill
5.8%inclusion8 decks139 decks
-2%synergy
Blood Pact
5.3%inclusion38 decks714 decks
1%synergy
Sorceries
Feed the Swarm
54%inclusion386 decks714 decks
3%synergy
Night's Whisper
46%inclusion330 decks714 decks
22%synergy
Crux of Fate
41%inclusion290 decks714 decks
39%synergy
Toxic Deluge
39%inclusion282 decks714 decks
2%synergy
Caress of Phyrexia
39%inclusion277 decks714 decks
38%synergy
Read the Bones
34%inclusion241 decks714 decks
16%synergy
Bubbling Muck
31%inclusion218 decks714 decks
15%synergy
Damnation
27%inclusion191 decks714 decks
6%synergy
Vat Emergence
24%inclusion174 decks714 decks
23%synergy
Reanimate
24%inclusion168 decks714 decks
-15%synergy
Diabolic Tutor
23%inclusion162 decks714 decks
8%synergy
Spread the Sickness
19%inclusion135 decks714 decks
18%synergy
Mutilate
18%inclusion129 decks714 decks
-1%synergy
Insatiable Avarice
18%inclusion111 decks621 decks
6%synergy
Grim Tutor
15%inclusion110 decks714 decks
3%synergy
Blasphemous Edict
13%inclusion43 decks329 decks
-4%synergy
Geth's Summons
13%inclusion91 decks714 decks
12%synergy
Exsanguinate
12%inclusion89 decks714 decks
-12%synergy
Black Sun's Zenith
12%inclusion85 decks714 decks
6%synergy
Feed the Infection
8.8%inclusion63 decks714 decks
8%synergy
In Garruk's Wake
7.7%inclusion55 decks714 decks
3%synergy
Beseech the Queen
7.6%inclusion54 decks714 decks
1%synergy
Profane Tutor
7.4%inclusion53 decks714 decks
3%synergy
Syphon Mind
7.1%inclusion51 decks714 decks
-6%synergy
Torment of Hailfire
6.3%inclusion45 decks714 decks
-10%synergy
Fell
6.2%inclusion30 decks483 decks
3%synergy
Praetor's Grasp
5.3%inclusion38 decks714 decks
1%synergy
Villainous Wrath
5.1%inclusion5 decks99 decks
3%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion369 decks714 decks
49%synergy
Lightning Greaves
51%inclusion367 decks714 decks
18%synergy
Fireshrieker
46%inclusion330 decks714 decks
44%synergy
Contagion Clasp
43%inclusion306 decks714 decks
40%synergy
Whispersilk Cloak
40%inclusion289 decks714 decks
35%synergy
Contagion Engine
37%inclusion264 decks714 decks
35%synergy
Sword of Truth and Justice
36%inclusion259 decks714 decks
35%synergy
Commander's Plate
36%inclusion254 decks714 decks
30%synergy
Shadowspear
27%inclusion196 decks714 decks
24%synergy
The Darkness Crystal
26%inclusion38 decks145 decks
6%synergy
Leyline Axe
22%inclusion74 decks331 decks
21%synergy
Champion's Helm
20%inclusion146 decks714 decks
18%synergy
Hero's Blade
19%inclusion139 decks714 decks
19%synergy
Trailblazer's Boots
19%inclusion136 decks714 decks
17%synergy
Brotherhood Regalia
17%inclusion86 decks505 decks
15%synergy
Sword of the Animist
16%inclusion116 decks714 decks
12%synergy
Cranial Plating
15%inclusion105 decks714 decks
11%synergy
Pact Weapon
14%inclusion103 decks714 decks
12%synergy
Mithril Coat
14%inclusion103 decks714 decks
9%synergy
Throne of Geth
14%inclusion101 decks714 decks
14%synergy
Genji Glove
14%inclusion19 decks138 decks
13%synergy
Sword of Feast and Famine
13%inclusion93 decks714 decks
11%synergy
Expedition Map
13%inclusion92 decks714 decks
0%synergy
Wayfarer's Bauble
13%inclusion91 decks714 decks
-4%synergy
Strata Scythe
11%inclusion78 decks714 decks
10%synergy
Grafted Exoskeleton
11%inclusion77 decks714 decks
10%synergy
Doc Ock's Tentacles
10%inclusion10 decks99 decks
10%synergy
Inquisitor's Flail
10%inclusion72 decks714 decks
10%synergy
Sword of Vengeance
10%inclusion71 decks714 decks
9%synergy
Bontu's Monument
8.4%inclusion60 decks714 decks
-19%synergy
Loxodon Warhammer
8.4%inclusion60 decks714 decks
7%synergy
Hammer of Nazahn
8.3%inclusion59 decks714 decks
8%synergy
Pip-Boy 3000
8.3%inclusion55 decks666 decks
8%synergy
Prowler's Helm
8.1%inclusion58 decks714 decks
7%synergy
Helm of the Host
8.1%inclusion58 decks714 decks
7%synergy
Grafted Wargear
7.7%inclusion55 decks714 decks
7%synergy
Darksteel Plate
7.7%inclusion55 decks714 decks
6%synergy
Basilisk Collar
7.4%inclusion53 decks714 decks
5%synergy
Sword of Wealth and Power
7.3%inclusion49 decks667 decks
7%synergy
Sensei's Divining Top
7.3%inclusion52 decks714 decks
-1%synergy
Vorpal Sword
7.3%inclusion52 decks714 decks
3%synergy
O-Naginata
6.9%inclusion49 decks714 decks
7%synergy
Whip of Erebos
6.7%inclusion48 decks714 decks
-4%synergy
Manifold Key
5.3%inclusion38 decks714 decks
4%synergy
Sword of Fire and Ice
5.2%inclusion37 decks714 decks
5%synergy
Decimator Web
5.2%inclusion37 decks714 decks
5%synergy
Prosthetic Injector
5.0%inclusion36 decks714 decks
5%synergy
Mask of Avacyn
5.0%inclusion36 decks714 decks
4%synergy
Enchantments
Necrogen Communion
51%inclusion362 decks714 decks
49%synergy
Unspeakable Symbol
39%inclusion282 decks714 decks
39%synergy
Kaya's Ghostform
30%inclusion212 decks714 decks
20%synergy
Black Market Connections
21%inclusion152 decks714 decks
-2%synergy
Bad Moon
21%inclusion148 decks714 decks
17%synergy
Fungal Fortitude
18%inclusion132 decks714 decks
17%synergy
Phyresis
16%inclusion112 decks714 decks
14%synergy
Relic Putrescence
15%inclusion109 decks714 decks
15%synergy
No Mercy
15%inclusion107 decks714 decks
8%synergy
Endless Scream
15%inclusion105 decks714 decks
14%synergy
Shade's Form
11%inclusion81 decks714 decks
11%synergy
Dauthi Embrace
11%inclusion75 decks714 decks
9%synergy
Snake Cult Initiation
8.0%inclusion57 decks714 decks
8%synergy
Animate Dead
7.3%inclusion52 decks714 decks
-10%synergy
Black Market
6.9%inclusion49 decks714 decks
-14%synergy
Super State
6.4%inclusion8 decks125 decks
6%synergy
Alien Symbiosis
6.1%inclusion6 decks99 decks
6%synergy
Greed
5.9%inclusion42 decks714 decks
-1%synergy
Glistening Oil
5.7%inclusion41 decks714 decks
5%synergy
The Meathook Massacre
5.3%inclusion38 decks714 decks
-12%synergy
Phyrexian Reclamation
5.2%inclusion37 decks714 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion326 decks714 decks
43%synergy
Liliana of the Dark Realms
27%inclusion196 decks714 decks
13%synergy
Utility Lands
Rogue's Passage
68%inclusion482 decks714 decks
49%synergy
Cabal Coffers
61%inclusion437 decks714 decks
6%synergy
Bojuka Bog
48%inclusion344 decks714 decks
1%synergy
Urborg, Tomb of Yawgmoth
47%inclusion336 decks714 decks
9%synergy
Shizo, Death's Storehouse
44%inclusion313 decks714 decks
34%synergy
Inkmoth Nexus
41%inclusion295 decks714 decks
40%synergy
Cabal Stronghold
37%inclusion264 decks714 decks
1%synergy
Nykthos, Shrine to Nyx
25%inclusion179 decks714 decks
-5%synergy
The Black Gate
20%inclusion146 decks714 decks
17%synergy
Cathedral of War
19%inclusion136 decks714 decks
19%synergy
Castle Locthwain
18%inclusion127 decks714 decks
0%synergy
Command Beacon
17%inclusion119 decks714 decks
8%synergy
War Room
16%inclusion112 decks714 decks
-1%synergy
Reliquary Tower
14%inclusion102 decks714 decks
-17%synergy
Witch's Cottage
13%inclusion91 decks714 decks
-12%synergy
Urza's Saga
11%inclusion81 decks714 decks
3%synergy
Minas Morgul, Dark Fortress
11%inclusion81 decks714 decks
8%synergy
Mortuary Mire
10%inclusion72 decks714 decks
-3%synergy
Temple of the False God
10%inclusion69 decks714 decks
2%synergy
Lake of the Dead
9.2%inclusion66 decks714 decks
4%synergy
Strip Mine
8.7%inclusion62 decks714 decks
6%synergy
Takenuma, Abandoned Mire
8.1%inclusion58 decks714 decks
-8%synergy
Barren Moor
8.0%inclusion57 decks714 decks
-2%synergy
Maze of Ith
6.6%inclusion47 decks714 decks
3%synergy
Buried Ruin
6.2%inclusion44 decks714 decks
1%synergy
Phyrexian Tower
6.0%inclusion43 decks714 decks
-18%synergy
Thespian's Stage
5.6%inclusion40 decks714 decks
0%synergy
Spymaster's Vault
5.4%inclusion29 decks540 decks
-4%synergy
Homeward Path
5.2%inclusion37 decks714 decks
3%synergy
Mana Artifacts
Sol Ring
91%inclusion648 decks714 decks
4%synergy
Arcane Signet
65%inclusion464 decks714 decks
2%synergy
Glistening Sphere
46%inclusion328 decks714 decks
45%synergy
Mind Stone
33%inclusion236 decks714 decks
2%synergy
Charcoal Diamond
31%inclusion222 decks714 decks
8%synergy
Staff of Compleation
28%inclusion201 decks714 decks
26%synergy
Heraldic Banner
19%inclusion134 decks714 decks
13%synergy
The Soul Stone
18%inclusion21 decks117 decks
5%synergy
Caged Sun
17%inclusion124 decks714 decks
5%synergy
Thought Vessel
15%inclusion108 decks714 decks
-12%synergy
Fellwar Stone
15%inclusion104 decks714 decks
0%synergy
Lotus Petal
13%inclusion92 decks714 decks
5%synergy
Commander's Sphere
11%inclusion81 decks714 decks
2%synergy
Throne of Eldraine
11%inclusion80 decks714 decks
1%synergy
Everflowing Chalice
10%inclusion71 decks714 decks
4%synergy
Mox Opal
10%inclusion70 decks714 decks
6%synergy
Jeweled Lotus
9.0%inclusion64 decks714 decks
6%synergy
Thran Dynamo
7.6%inclusion54 decks714 decks
1%synergy
Mana Crypt
7.3%inclusion52 decks714 decks
5%synergy
Sceptre of Eternal Glory
6.9%inclusion49 decks714 decks
-2%synergy
Worn Powerstone
6.3%inclusion45 decks714 decks
2%synergy
Gilded Lotus
5.7%inclusion41 decks714 decks
0%synergy
Mox Diamond
5.6%inclusion40 decks714 decks
2%synergy
Nyx Lotus
5.3%inclusion38 decks714 decks
-2%synergy
Extraplanar Lens
5.0%inclusion36 decks714 decks
0%synergy
Phyrexian Atlas
5.0%inclusion36 decks714 decks
5%synergy
Lands
Swamp
95%inclusion679 decks714 decks
0%synergy
Myriad Landscape
24%inclusion171 decks714 decks
-3%synergy
Malakir Rebirth
17%inclusion124 decks714 decks
-5%synergy
Cavern of Souls
16%inclusion114 decks714 decks
9%synergy
Mirrex
16%inclusion112 decks714 decks
15%synergy
Fell the Profane
14%inclusion75 decks540 decks
-5%synergy
Opal Palace
8.5%inclusion61 decks714 decks
8%synergy
Urza's Cave
7.7%inclusion44 decks571 decks
-1%synergy
The Seedcore
7.3%inclusion52 decks714 decks
7%synergy
Snow-Covered Swamp
5.9%inclusion42 decks714 decks
-1%synergy
Command Tower
5.3%inclusion38 decks714 decks
0%synergy
Polluted Delta
5.3%inclusion38 decks714 decks
2%synergy
Bloodstained Mire
5.3%inclusion38 decks714 decks
2%synergy
Verdant Catacombs
5.2%inclusion37 decks714 decks
2%synergy
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