Skithiryx, the Blight Dragon (Commander) - Core

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
Mana Artifacts
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Fatal Fissure
8.0%inclusion2 decks25 decks
8%synergy
Zuko's Conviction
4.3%inclusion1 decks23 decks
3%synergy
Kyoshi Battle Fan
4.0%inclusion1 decks25 decks
4%synergy
Deadly Precision
3.7%inclusion1 decks27 decks
3%synergy
Secret Tunnel
3.6%inclusion1 decks28 decks
3%synergy
High Synergy Cards
Plague Stinger
69%inclusion212 decks307 decks
68%synergy
Lashwrithe
70%inclusion216 decks307 decks
66%synergy
Plague Myr
67%inclusion207 decks307 decks
66%synergy
Infectious Inquiry
69%inclusion212 decks307 decks
66%synergy
Ichor Rats
67%inclusion205 decks307 decks
64%synergy
Vraska's Fall
66%inclusion202 decks307 decks
62%synergy
Hand of the Praetors
62%inclusion189 decks307 decks
61%synergy
Whispering Specter
58%inclusion178 decks307 decks
57%synergy
Drown in Ichor
61%inclusion187 decks307 decks
57%synergy
Fireshrieker
57%inclusion175 decks307 decks
55%synergy
Top Cards
Dark Ritual
68%inclusion210 decks307 decks
2%synergy
Swiftfoot Boots
64%inclusion195 decks307 decks
32%synergy
Blackblade Reforged
57%inclusion175 decks307 decks
54%synergy
Sign in Blood
56%inclusion171 decks307 decks
19%synergy
Blightbelly Rat
55%inclusion169 decks307 decks
51%synergy
Nightmare Lash
54%inclusion167 decks307 decks
52%synergy
Howl from Beyond
54%inclusion167 decks307 decks
54%synergy
Reaper of Sheoldred
53%inclusion164 decks307 decks
53%synergy
Phyrexian Arena
52%inclusion161 decks307 decks
12%synergy
Feed the Swarm
52%inclusion159 decks307 decks
1%synergy
Game Changers
Necropotence
6.8%inclusion21 decks307 decks
-8%synergy
Creatures
Phyrexian Crusader
49%inclusion150 decks307 decks
48%synergy
Ichorclaw Myr
48%inclusion146 decks307 decks
47%synergy
Core Prowler
48%inclusion146 decks307 decks
47%synergy
Flensermite
45%inclusion139 decks307 decks
45%synergy
Crypt Ghast
45%inclusion138 decks307 decks
-3%synergy
Corpse Cur
44%inclusion135 decks307 decks
44%synergy
Flesh-Eater Imp
41%inclusion127 decks307 decks
41%synergy
Bilious Skulldweller
41%inclusion126 decks307 decks
40%synergy
Septic Rats
38%inclusion117 decks307 decks
36%synergy
Pestilent Syphoner
37%inclusion113 decks307 decks
36%synergy
Necropede
30%inclusion91 decks307 decks
29%synergy
Solemn Simulacrum
29%inclusion88 decks307 decks
5%synergy
Leaden Myr
29%inclusion88 decks307 decks
22%synergy
Contagious Nim
27%inclusion82 decks307 decks
26%synergy
Phyrexian Obliterator
27%inclusion82 decks307 decks
16%synergy
Myr Convert
25%inclusion78 decks307 decks
25%synergy
Blackcleave Goblin
22%inclusion68 decks307 decks
22%synergy
K'rrik, Son of Yawgmoth
21%inclusion65 decks307 decks
2%synergy
Gulping Scraptrap
21%inclusion63 decks307 decks
20%synergy
Gray Merchant of Asphodel
20%inclusion61 decks307 decks
-32%synergy
Phyrexian Juggernaut
19%inclusion59 decks307 decks
19%synergy
Toxic Nim
16%inclusion49 decks307 decks
16%synergy
Dread Presence
15%inclusion46 decks307 decks
0%synergy
Defiler of Flesh
15%inclusion46 decks307 decks
11%synergy
Sheoldred's Headcleaver
15%inclusion45 decks307 decks
14%synergy
Burnished Hart
14%inclusion42 decks307 decks
6%synergy
Phyrexian Vatmother
14%inclusion42 decks307 decks
14%synergy
Magus of the Coffers
13%inclusion41 decks307 decks
6%synergy
Blightsteel Colossus
13%inclusion40 decks307 decks
12%synergy
Brass Squire
13%inclusion39 decks307 decks
12%synergy
Paragon of Open Graves
11%inclusion34 decks307 decks
10%synergy
Grafted Butcher
11%inclusion33 decks307 decks
11%synergy
Silent Arbiter
10%inclusion32 decks307 decks
9%synergy
Necroskitter
10%inclusion32 decks307 decks
7%synergy
Yawgmoth, Thran Physician
10%inclusion31 decks307 decks
0%synergy
Nimraiser Paladin
10%inclusion31 decks307 decks
10%synergy
Massacre Girl, Known Killer
9.4%inclusion29 decks307 decks
6%synergy
Nirkana Revenant
9.4%inclusion29 decks307 decks
-2%synergy
Phyrexian Digester
9.1%inclusion28 decks307 decks
9%synergy
Swamp Mosquito
9.1%inclusion28 decks307 decks
9%synergy
Sheoldred, Whispering One
9.1%inclusion28 decks307 decks
-3%synergy
Vector Asp
9.1%inclusion28 decks307 decks
9%synergy
Murderous Rider
8.5%inclusion26 decks307 decks
2%synergy
Scourge Servant
7.5%inclusion23 decks307 decks
7%synergy
Palladium Myr
7.5%inclusion23 decks307 decks
6%synergy
Virulent Silencer
7.4%inclusion5 decks68 decks
7%synergy
Suspicious Bookcase
6.5%inclusion20 decks307 decks
6%synergy
Xu-Ifit, Osteoharmonist
6.0%inclusion4 decks67 decks
4%synergy
Surge Conductor
5.9%inclusion4 decks68 decks
6%synergy
Massacre Wurm
5.9%inclusion18 decks307 decks
-12%synergy
Instants
Defile
50%inclusion154 decks307 decks
13%synergy
Whisper of the Dross
43%inclusion131 decks307 decks
40%synergy
Go for the Throat
42%inclusion129 decks307 decks
19%synergy
Grim Affliction
39%inclusion121 decks307 decks
37%synergy
Infernal Grasp
34%inclusion103 decks307 decks
8%synergy
Tainted Strike
33%inclusion100 decks307 decks
29%synergy
Sugar Rush
29%inclusion88 decks307 decks
28%synergy
Supernatural Stamina
27%inclusion82 decks307 decks
19%synergy
Doom Blade
24%inclusion73 decks307 decks
16%synergy
Dismember
23%inclusion71 decks307 decks
12%synergy
Virulent Wound
20%inclusion60 decks307 decks
19%synergy
Astarion's Thirst
19%inclusion59 decks307 decks
18%synergy
Withering Torment
19%inclusion40 decks210 decks
-13%synergy
Imp's Mischief
18%inclusion54 decks307 decks
-6%synergy
Consuming Corruption
17%inclusion45 decks258 decks
1%synergy
Hero's Downfall
17%inclusion53 decks307 decks
10%synergy
Sudden Spoiling
17%inclusion51 decks307 decks
7%synergy
Unlikely Aid
16%inclusion50 decks307 decks
16%synergy
Murder
15%inclusion46 decks307 decks
5%synergy
Anoint with Affliction
15%inclusion45 decks307 decks
14%synergy
Malakir Rebirth
14%inclusion44 decks307 decks
-8%synergy
Deadly Rollick
14%inclusion44 decks307 decks
-9%synergy
Tragic Slip
13%inclusion39 decks307 decks
-8%synergy
Undying Malice
11%inclusion34 decks307 decks
2%synergy
Cabal Ritual
11%inclusion33 decks307 decks
-7%synergy
Archenemy's Charm
10%inclusion7 decks68 decks
1%synergy
Professor's Warning
10%inclusion30 decks307 decks
8%synergy
Snuff Out
9.4%inclusion29 decks307 decks
-3%synergy
Fell the Profane
9.3%inclusion24 decks259 decks
-10%synergy
Rush of Vitality
8.8%inclusion27 decks307 decks
8%synergy
Soul Shatter
8.5%inclusion26 decks307 decks
-4%synergy
Hatred
8.1%inclusion25 decks307 decks
7%synergy
Sheoldred's Edict
8.1%inclusion25 decks307 decks
-6%synergy
Darkness
7.8%inclusion24 decks307 decks
-2%synergy
Force of Despair
7.8%inclusion24 decks307 decks
0%synergy
Baleful Mastery
7.2%inclusion22 decks307 decks
-2%synergy
Undying Evil
6.5%inclusion20 decks307 decks
3%synergy
Blood Pact
6.5%inclusion20 decks307 decks
2%synergy
Not Dead After All
6.5%inclusion20 decks307 decks
-5%synergy
Deadly Dispute
6.2%inclusion19 decks307 decks
-18%synergy
Heartless Act
5.5%inclusion17 decks307 decks
4%synergy
Withering Boon
5.5%inclusion17 decks307 decks
1%synergy
Grotesque Mutation
5.2%inclusion16 decks307 decks
5%synergy
Sorceries
Phyresis Outbreak
46%inclusion142 decks307 decks
44%synergy
Night's Whisper
44%inclusion134 decks307 decks
19%synergy
Read the Bones
43%inclusion132 decks307 decks
25%synergy
Caress of Phyrexia
41%inclusion127 decks307 decks
41%synergy
Crux of Fate
39%inclusion121 decks307 decks
38%synergy
Vat Emergence
31%inclusion94 decks307 decks
29%synergy
Spread the Sickness
25%inclusion78 decks307 decks
25%synergy
Mutilate
24%inclusion75 decks307 decks
6%synergy
Toxic Deluge
22%inclusion68 decks307 decks
-15%synergy
Diabolic Tutor
21%inclusion63 decks307 decks
6%synergy
Bubbling Muck
19%inclusion59 decks307 decks
4%synergy
Geth's Summons
15%inclusion46 decks307 decks
15%synergy
Feed the Infection
14%inclusion43 decks307 decks
13%synergy
Black Sun's Zenith
13%inclusion39 decks307 decks
7%synergy
Reanimate
13%inclusion39 decks307 decks
-26%synergy
Insatiable Avarice
12%inclusion35 decks283 decks
0%synergy
Exsanguinate
12%inclusion37 decks307 decks
-12%synergy
In Garruk's Wake
12%inclusion36 decks307 decks
8%synergy
Syphon Mind
11%inclusion35 decks307 decks
-1%synergy
Damnation
11%inclusion34 decks307 decks
-10%synergy
Blasphemous Edict
9.1%inclusion17 decks186 decks
-8%synergy
Languish
7.2%inclusion22 decks307 decks
6%synergy
Ancient Craving
7.2%inclusion22 decks307 decks
5%synergy
Fell
6.9%inclusion17 decks245 decks
3%synergy
Duress
6.8%inclusion21 decks307 decks
0%synergy
Ambition's Cost
6.2%inclusion19 decks307 decks
3%synergy
Profane Tutor
6.2%inclusion19 decks307 decks
2%synergy
Necromantic Selection
5.2%inclusion16 decks307 decks
3%synergy
Utility Artifacts
Contagion Clasp
45%inclusion138 decks307 decks
42%synergy
Whispersilk Cloak
40%inclusion124 decks307 decks
34%synergy
Jet Medallion
40%inclusion123 decks307 decks
-20%synergy
Lightning Greaves
37%inclusion115 decks307 decks
4%synergy
Contagion Engine
32%inclusion98 decks307 decks
30%synergy
Hero's Blade
28%inclusion87 decks307 decks
28%synergy
Wayfarer's Bauble
22%inclusion69 decks307 decks
6%synergy
Trailblazer's Boots
22%inclusion67 decks307 decks
20%synergy
The Darkness Crystal
21%inclusion18 decks86 decks
1%synergy
Champion's Helm
20%inclusion60 decks307 decks
18%synergy
Leyline Axe
19%inclusion35 decks186 decks
18%synergy
Sword of Truth and Justice
17%inclusion53 decks307 decks
16%synergy
Pact Weapon
17%inclusion52 decks307 decks
15%synergy
Strata Scythe
16%inclusion49 decks307 decks
15%synergy
Grafted Exoskeleton
16%inclusion48 decks307 decks
14%synergy
Sword of Vengeance
15%inclusion47 decks307 decks
14%synergy
Cranial Plating
15%inclusion47 decks307 decks
12%synergy
Throne of Geth
15%inclusion46 decks307 decks
15%synergy
Commander's Plate
15%inclusion45 decks307 decks
9%synergy
Prowler's Helm
13%inclusion39 decks307 decks
12%synergy
Sword of the Animist
13%inclusion39 decks307 decks
9%synergy
Brotherhood Regalia
13%inclusion31 decks248 decks
10%synergy
Loxodon Warhammer
12%inclusion38 decks307 decks
11%synergy
Bontu's Monument
12%inclusion38 decks307 decks
-15%synergy
Genji Glove
12%inclusion10 decks83 decks
11%synergy
Doc Ock's Tentacles
12%inclusion6 decks52 decks
11%synergy
Vorpal Sword
11%inclusion35 decks307 decks
7%synergy
Inquisitor's Flail
11%inclusion34 decks307 decks
11%synergy
Expedition Map
10%inclusion31 decks307 decks
-2%synergy
Grafted Wargear
10%inclusion30 decks307 decks
10%synergy
Shadowspear
10%inclusion30 decks307 decks
6%synergy
O-Naginata
9.4%inclusion29 decks307 decks
9%synergy
Mask of Avacyn
9.1%inclusion28 decks307 decks
8%synergy
Decimator Web
8.1%inclusion25 decks307 decks
8%synergy
Mithril Coat
8.1%inclusion25 decks307 decks
3%synergy
Nettlecyst
7.2%inclusion22 decks307 decks
6%synergy
Darksteel Plate
6.2%inclusion19 decks307 decks
4%synergy
Lavaspur Boots
6.0%inclusion17 decks285 decks
4%synergy
Buster Sword
6.0%inclusion5 decks84 decks
5%synergy
Prosthetic Injector
5.9%inclusion18 decks307 decks
6%synergy
Livewire Lash
5.5%inclusion17 decks307 decks
5%synergy
Basilisk Collar
5.5%inclusion17 decks307 decks
3%synergy
Bladed Battle-Fan
5.5%inclusion17 decks307 decks
5%synergy
Hammer of Nazahn
5.5%inclusion17 decks307 decks
5%synergy
Sword of Feast and Famine
5.2%inclusion16 decks307 decks
3%synergy
Thran Power Suit
5.2%inclusion16 decks307 decks
5%synergy
Enchantments
Necrogen Communion
45%inclusion138 decks307 decks
43%synergy
Kaya's Ghostform
32%inclusion98 decks307 decks
22%synergy
Unspeakable Symbol
27%inclusion84 decks307 decks
26%synergy
Bad Moon
25%inclusion76 decks307 decks
21%synergy
Relic Putrescence
20%inclusion62 decks307 decks
20%synergy
Fungal Fortitude
19%inclusion59 decks307 decks
18%synergy
Endless Scream
18%inclusion56 decks307 decks
18%synergy
Phyresis
16%inclusion49 decks307 decks
14%synergy
Shade's Form
14%inclusion42 decks307 decks
13%synergy
Black Market
12%inclusion37 decks307 decks
-9%synergy
Underworld Connections
10%inclusion32 decks307 decks
8%synergy
Black Market Connections
10%inclusion32 decks307 decks
-13%synergy
No Mercy
10%inclusion31 decks307 decks
3%synergy
Dauthi Embrace
10%inclusion30 decks307 decks
8%synergy
Greed
8.5%inclusion26 decks307 decks
1%synergy
Snake Cult Initiation
7.5%inclusion23 decks307 decks
7%synergy
Super State
6.8%inclusion5 decks74 decks
7%synergy
Corpses of the Lost
6.5%inclusion20 decks307 decks
5%synergy
Glistening Oil
6.2%inclusion19 decks307 decks
5%synergy
Alien Symbiosis
6.1%inclusion3 decks49 decks
6%synergy
Planeswalkers
Vraska, Betrayal's Sting
31%inclusion94 decks307 decks
28%synergy
Liliana of the Dark Realms
19%inclusion57 decks307 decks
4%synergy
Utility Lands
Rogue's Passage
64%inclusion196 decks307 decks
45%synergy
Karn's Bastion
56%inclusion171 decks307 decks
51%synergy
Bojuka Bog
42%inclusion129 decks307 decks
-5%synergy
Cabal Coffers
37%inclusion113 decks307 decks
-18%synergy
Cabal Stronghold
26%inclusion81 decks307 decks
-9%synergy
Shizo, Death's Storehouse
21%inclusion65 decks307 decks
11%synergy
Inkmoth Nexus
21%inclusion63 decks307 decks
20%synergy
Cathedral of War
20%inclusion61 decks307 decks
19%synergy
Urborg, Tomb of Yawgmoth
20%inclusion60 decks307 decks
-18%synergy
War Room
13%inclusion41 decks307 decks
-3%synergy
Witch's Cottage
12%inclusion38 decks307 decks
-12%synergy
Castle Locthwain
12%inclusion38 decks307 decks
-5%synergy
Temple of the False God
12%inclusion36 decks307 decks
4%synergy
Mortuary Mire
9.1%inclusion28 decks307 decks
-4%synergy
The Black Gate
9.1%inclusion28 decks307 decks
6%synergy
Nykthos, Shrine to Nyx
9.1%inclusion28 decks307 decks
-21%synergy
Reliquary Tower
9.1%inclusion28 decks307 decks
-22%synergy
Barren Moor
8.1%inclusion25 decks307 decks
-2%synergy
Command Beacon
7.8%inclusion24 decks307 decks
0%synergy
Minas Morgul, Dark Fortress
7.5%inclusion23 decks307 decks
4%synergy
Buried Ruin
5.2%inclusion16 decks307 decks
0%synergy
Mana Artifacts
Sol Ring
84%inclusion258 decks307 decks
-2%synergy
Arcane Signet
61%inclusion187 decks307 decks
-2%synergy
Charcoal Diamond
41%inclusion127 decks307 decks
18%synergy
Mind Stone
38%inclusion116 decks307 decks
7%synergy
Glistening Sphere
33%inclusion102 decks307 decks
32%synergy
Heraldic Banner
22%inclusion69 decks307 decks
17%synergy
Caged Sun
18%inclusion54 decks307 decks
5%synergy
Thought Vessel
16%inclusion48 decks307 decks
-11%synergy
Fellwar Stone
15%inclusion47 decks307 decks
1%synergy
Commander's Sphere
15%inclusion47 decks307 decks
6%synergy
Staff of Compleation
15%inclusion46 decks307 decks
13%synergy
Gilded Lotus
13%inclusion41 decks307 decks
8%synergy
Everflowing Chalice
11%inclusion33 decks307 decks
5%synergy
Thran Dynamo
11%inclusion33 decks307 decks
5%synergy
Worn Powerstone
10%inclusion30 decks307 decks
5%synergy
Throne of Eldraine
7.5%inclusion23 decks307 decks
-3%synergy
Sceptre of Eternal Glory
6.8%inclusion21 decks307 decks
-2%synergy
Hedron Archive
5.2%inclusion16 decks307 decks
1%synergy
Lands
Swamp
98%inclusion300 decks307 decks
3%synergy
Myriad Landscape
28%inclusion85 decks307 decks
1%synergy
Malakir Rebirth
14%inclusion44 decks307 decks
-8%synergy
Mirrex
12%inclusion38 decks307 decks
12%synergy
Opal Palace
11%inclusion33 decks307 decks
10%synergy
Fell the Profane
9.3%inclusion24 decks259 decks
-10%synergy
Command Tower
6.5%inclusion20 decks307 decks
1%synergy
The Seedcore
5.5%inclusion17 decks307 decks
5%synergy
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