Skithiryx, the Blight Dragon (Commander) - Core

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #784
300decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Sorceries
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Enchantments
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Utility Lands
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Madame Null, Power Broker
5.7%inclusion2 decks35 decks
5%synergy
Shredder's Technique
4.3%inclusion1 decks23 decks
1%synergy
Rat King, Verminister
2.9%inclusion1 decks35 decks
0%synergy
High Synergy Cards
Plague Stinger
69%inclusion207 decks300 decks
68%synergy
Plague Myr
68%inclusion204 decks300 decks
67%synergy
Infectious Inquiry
69%inclusion206 decks300 decks
66%synergy
Lashwrithe
69%inclusion208 decks300 decks
65%synergy
Ichor Rats
67%inclusion200 decks300 decks
64%synergy
Vraska's Fall
65%inclusion196 decks300 decks
62%synergy
Hand of the Praetors
62%inclusion185 decks300 decks
61%synergy
Whispering Specter
60%inclusion181 decks300 decks
60%synergy
Drown in Ichor
62%inclusion187 decks300 decks
58%synergy
Fireshrieker
57%inclusion170 decks300 decks
55%synergy
Top Cards
Dark Ritual
68%inclusion203 decks300 decks
1%synergy
Swiftfoot Boots
64%inclusion191 decks300 decks
32%synergy
Blightbelly Rat
57%inclusion172 decks300 decks
54%synergy
Blackblade Reforged
57%inclusion171 decks300 decks
54%synergy
Sign in Blood
56%inclusion168 decks300 decks
20%synergy
Reaper of Sheoldred
55%inclusion164 decks300 decks
54%synergy
Howl from Beyond
54%inclusion162 decks300 decks
53%synergy
Nightmare Lash
53%inclusion159 decks300 decks
51%synergy
Feed the Swarm
53%inclusion158 decks300 decks
2%synergy
Defile
52%inclusion156 decks300 decks
15%synergy
Game Changers
Necropotence
6.7%inclusion20 decks300 decks
-8%synergy
Creatures
Core Prowler
49%inclusion148 decks300 decks
49%synergy
Ichorclaw Myr
49%inclusion146 decks300 decks
48%synergy
Phyrexian Crusader
47%inclusion142 decks300 decks
46%synergy
Flensermite
47%inclusion140 decks300 decks
46%synergy
Corpse Cur
45%inclusion135 decks300 decks
45%synergy
Crypt Ghast
45%inclusion135 decks300 decks
-3%synergy
Bilious Skulldweller
44%inclusion131 decks300 decks
43%synergy
Flesh-Eater Imp
43%inclusion129 decks300 decks
42%synergy
Septic Rats
41%inclusion123 decks300 decks
39%synergy
Pestilent Syphoner
39%inclusion118 decks300 decks
39%synergy
Necropede
31%inclusion93 decks300 decks
31%synergy
Solemn Simulacrum
30%inclusion89 decks300 decks
7%synergy
Leaden Myr
30%inclusion89 decks300 decks
24%synergy
Contagious Nim
27%inclusion81 decks300 decks
27%synergy
Myr Convert
26%inclusion79 decks300 decks
26%synergy
Phyrexian Obliterator
26%inclusion78 decks300 decks
15%synergy
Blackcleave Goblin
23%inclusion70 decks300 decks
23%synergy
Gulping Scraptrap
23%inclusion69 decks300 decks
22%synergy
K'rrik, Son of Yawgmoth
22%inclusion65 decks300 decks
3%synergy
Phyrexian Juggernaut
20%inclusion60 decks300 decks
20%synergy
Gray Merchant of Asphodel
18%inclusion54 decks300 decks
-33%synergy
Toxic Nim
16%inclusion49 decks300 decks
16%synergy
Dread Presence
15%inclusion45 decks300 decks
1%synergy
Sheoldred's Headcleaver
15%inclusion45 decks300 decks
15%synergy
Blightsteel Colossus
15%inclusion45 decks300 decks
14%synergy
Phyrexian Vatmother
14%inclusion43 decks300 decks
14%synergy
Magus of the Coffers
14%inclusion42 decks300 decks
7%synergy
Defiler of Flesh
13%inclusion40 decks300 decks
9%synergy
Burnished Hart
13%inclusion40 decks300 decks
6%synergy
Brass Squire
12%inclusion36 decks300 decks
11%synergy
Yawgmoth, Thran Physician
11%inclusion33 decks300 decks
1%synergy
Phyrexian Digester
10%inclusion31 decks300 decks
10%synergy
Silent Arbiter
10%inclusion30 decks300 decks
9%synergy
Swamp Mosquito
10%inclusion30 decks300 decks
10%synergy
Nirkana Revenant
10%inclusion29 decks300 decks
-1%synergy
Paragon of Open Graves
10%inclusion29 decks300 decks
9%synergy
Necroskitter
10%inclusion29 decks300 decks
7%synergy
Vector Asp
9.3%inclusion28 decks300 decks
9%synergy
Nimraiser Paladin
9.3%inclusion28 decks300 decks
9%synergy
Grafted Butcher
8.7%inclusion26 decks300 decks
8%synergy
Sheoldred, Whispering One
8.7%inclusion26 decks300 decks
-3%synergy
Virulent Silencer
8.4%inclusion8 decks95 decks
8%synergy
Palladium Myr
8.3%inclusion25 decks300 decks
7%synergy
Scourge Servant
8.3%inclusion25 decks300 decks
8%synergy
Massacre Girl, Known Killer
8.3%inclusion25 decks300 decks
5%synergy
Murderous Rider
7.7%inclusion23 decks300 decks
1%synergy
Surge Conductor
7.4%inclusion7 decks95 decks
7%synergy
Scavenger Regent
6.3%inclusion8 decks127 decks
6%synergy
Suspicious Bookcase
6.0%inclusion18 decks300 decks
6%synergy
Stinging Hivemaster
5.7%inclusion17 decks300 decks
5%synergy
Instants
Whisper of the Dross
44%inclusion132 decks300 decks
41%synergy
Grim Affliction
42%inclusion125 decks300 decks
40%synergy
Go for the Throat
41%inclusion124 decks300 decks
18%synergy
Tainted Strike
34%inclusion102 decks300 decks
31%synergy
Infernal Grasp
32%inclusion97 decks300 decks
7%synergy
Sugar Rush
28%inclusion84 decks300 decks
28%synergy
Supernatural Stamina
26%inclusion78 decks300 decks
19%synergy
Dismember
24%inclusion71 decks300 decks
13%synergy
Doom Blade
23%inclusion70 decks300 decks
16%synergy
Withering Torment
20%inclusion46 decks230 decks
-12%synergy
Virulent Wound
19%inclusion58 decks300 decks
19%synergy
Astarion's Thirst
19%inclusion57 decks300 decks
18%synergy
Imp's Mischief
19%inclusion56 decks300 decks
-6%synergy
Consuming Corruption
17%inclusion48 decks278 decks
2%synergy
Murder
17%inclusion51 decks300 decks
7%synergy
Unlikely Aid
17%inclusion50 decks300 decks
16%synergy
Hero's Downfall
15%inclusion46 decks300 decks
9%synergy
Sudden Spoiling
15%inclusion46 decks300 decks
6%synergy
Malakir Rebirth
15%inclusion44 decks300 decks
-8%synergy
Anoint with Affliction
14%inclusion43 decks300 decks
14%synergy
Tragic Slip
14%inclusion41 decks300 decks
-6%synergy
Deadly Rollick
13%inclusion38 decks300 decks
-12%synergy
Cabal Ritual
11%inclusion33 decks300 decks
-7%synergy
Undying Malice
11%inclusion33 decks300 decks
1%synergy
Snuff Out
10%inclusion31 decks300 decks
-3%synergy
Fell the Profane
10%inclusion27 decks279 decks
-9%synergy
Professor's Warning
9.3%inclusion28 decks300 decks
8%synergy
Rush of Vitality
8.7%inclusion26 decks300 decks
8%synergy
Archenemy's Charm
8.4%inclusion8 decks95 decks
0%synergy
Soul Shatter
8.3%inclusion25 decks300 decks
-4%synergy
Hatred
8.0%inclusion24 decks300 decks
7%synergy
Sheoldred's Edict
7.7%inclusion23 decks300 decks
-7%synergy
Darkness
7.0%inclusion21 decks300 decks
-3%synergy
Baleful Mastery
7.0%inclusion21 decks300 decks
-2%synergy
Force of Despair
6.7%inclusion20 decks300 decks
-1%synergy
Not Dead After All
6.3%inclusion19 decks300 decks
-5%synergy
Undying Evil
6.0%inclusion18 decks300 decks
3%synergy
Deadly Dispute
6.0%inclusion18 decks300 decks
-20%synergy
Unnatural Endurance
6.0%inclusion18 decks300 decks
6%synergy
Withering Boon
5.7%inclusion17 decks300 decks
1%synergy
Blood Pact
5.7%inclusion17 decks300 decks
2%synergy
Grotesque Mutation
5.0%inclusion15 decks300 decks
5%synergy
Sorceries
Phyresis Outbreak
46%inclusion137 decks300 decks
44%synergy
Night's Whisper
45%inclusion134 decks300 decks
20%synergy
Caress of Phyrexia
43%inclusion128 decks300 decks
42%synergy
Read the Bones
42%inclusion126 decks300 decks
25%synergy
Crux of Fate
41%inclusion123 decks300 decks
40%synergy
Vat Emergence
31%inclusion94 decks300 decks
30%synergy
Spread the Sickness
25%inclusion76 decks300 decks
25%synergy
Mutilate
24%inclusion71 decks300 decks
6%synergy
Toxic Deluge
22%inclusion65 decks300 decks
-15%synergy
Diabolic Tutor
21%inclusion62 decks300 decks
6%synergy
Bubbling Muck
19%inclusion56 decks300 decks
3%synergy
Feed the Infection
15%inclusion45 decks300 decks
14%synergy
Geth's Summons
15%inclusion45 decks300 decks
15%synergy
Reanimate
13%inclusion40 decks300 decks
-26%synergy
Black Sun's Zenith
13%inclusion38 decks300 decks
7%synergy
Exsanguinate
13%inclusion38 decks300 decks
-12%synergy
Syphon Mind
12%inclusion35 decks300 decks
-1%synergy
Insatiable Avarice
11%inclusion34 decks300 decks
0%synergy
In Garruk's Wake
11%inclusion32 decks300 decks
7%synergy
Damnation
10%inclusion31 decks300 decks
-10%synergy
Blasphemous Edict
8.7%inclusion18 decks207 decks
-8%synergy
Ancient Craving
7.3%inclusion22 decks300 decks
5%synergy
Languish
7.3%inclusion22 decks300 decks
6%synergy
Duress
7.0%inclusion21 decks300 decks
0%synergy
Fell
6.8%inclusion18 decks265 decks
3%synergy
Profane Tutor
5.7%inclusion17 decks300 decks
1%synergy
Ambition's Cost
5.7%inclusion17 decks300 decks
3%synergy
Gix's Command
5.3%inclusion16 decks300 decks
3%synergy
Necromantic Selection
5.3%inclusion16 decks300 decks
3%synergy
Decree of Pain
5.0%inclusion15 decks300 decks
0%synergy
Utility Artifacts
Contagion Clasp
45%inclusion136 decks300 decks
43%synergy
Jet Medallion
42%inclusion127 decks300 decks
-19%synergy
Whispersilk Cloak
41%inclusion122 decks300 decks
35%synergy
Lightning Greaves
36%inclusion108 decks300 decks
2%synergy
Contagion Engine
33%inclusion99 decks300 decks
31%synergy
Hero's Blade
27%inclusion82 decks300 decks
27%synergy
Trailblazer's Boots
24%inclusion73 decks300 decks
22%synergy
Wayfarer's Bauble
23%inclusion70 decks300 decks
8%synergy
Champion's Helm
20%inclusion61 decks300 decks
18%synergy
The Darkness Crystal
18%inclusion20 decks110 decks
-2%synergy
Sword of Truth and Justice
17%inclusion52 decks300 decks
17%synergy
Leyline Axe
17%inclusion35 decks207 decks
16%synergy
Pact Weapon
17%inclusion50 decks300 decks
14%synergy
Throne of Geth
15%inclusion46 decks300 decks
15%synergy
Commander's Plate
15%inclusion46 decks300 decks
9%synergy
Grafted Exoskeleton
15%inclusion46 decks300 decks
14%synergy
Strata Scythe
15%inclusion45 decks300 decks
14%synergy
Sword of Vengeance
15%inclusion44 decks300 decks
14%synergy
Cranial Plating
14%inclusion43 decks300 decks
11%synergy
Prowler's Helm
13%inclusion39 decks300 decks
12%synergy
Loxodon Warhammer
13%inclusion39 decks300 decks
12%synergy
Brotherhood Regalia
13%inclusion34 decks268 decks
10%synergy
Sword of the Animist
13%inclusion38 decks300 decks
9%synergy
Vorpal Sword
12%inclusion35 decks300 decks
8%synergy
Genji Glove
11%inclusion12 decks107 decks
10%synergy
Bontu's Monument
11%inclusion33 decks300 decks
-17%synergy
Inquisitor's Flail
11%inclusion33 decks300 decks
11%synergy
Expedition Map
10%inclusion30 decks300 decks
-2%synergy
Mask of Avacyn
10%inclusion30 decks300 decks
9%synergy
Shadowspear
10%inclusion29 decks300 decks
6%synergy
O-Naginata
9.3%inclusion28 decks300 decks
9%synergy
Grafted Wargear
9.3%inclusion28 decks300 decks
9%synergy
Doc Ock's Tentacles
8.9%inclusion7 decks79 decks
9%synergy
Decimator Web
7.7%inclusion23 decks300 decks
8%synergy
Mithril Coat
7.3%inclusion22 decks300 decks
2%synergy
Nettlecyst
6.7%inclusion20 decks300 decks
6%synergy
Darksteel Plate
6.7%inclusion20 decks300 decks
5%synergy
Lavaspur Boots
6.0%inclusion18 decks300 decks
4%synergy
Basilisk Collar
5.3%inclusion16 decks300 decks
3%synergy
Prosthetic Injector
5.3%inclusion16 decks300 decks
5%synergy
Thran Power Suit
5.0%inclusion15 decks300 decks
5%synergy
Livewire Lash
5.0%inclusion15 decks300 decks
5%synergy
Hammer of Nazahn
5.0%inclusion15 decks300 decks
4%synergy
Sword of Feast and Famine
5.0%inclusion15 decks300 decks
3%synergy
Enchantments
Phyrexian Arena
52%inclusion155 decks300 decks
12%synergy
Necrogen Communion
44%inclusion132 decks300 decks
42%synergy
Kaya's Ghostform
33%inclusion98 decks300 decks
23%synergy
Unspeakable Symbol
28%inclusion85 decks300 decks
27%synergy
Bad Moon
25%inclusion74 decks300 decks
21%synergy
Relic Putrescence
20%inclusion60 decks300 decks
20%synergy
Fungal Fortitude
19%inclusion56 decks300 decks
17%synergy
Endless Scream
18%inclusion54 decks300 decks
18%synergy
Phyresis
16%inclusion49 decks300 decks
14%synergy
Shade's Form
14%inclusion41 decks300 decks
13%synergy
Black Market Connections
11%inclusion33 decks300 decks
-13%synergy
Black Market
11%inclusion32 decks300 decks
-10%synergy
Dauthi Embrace
10%inclusion31 decks300 decks
9%synergy
Underworld Connections
10%inclusion30 decks300 decks
8%synergy
No Mercy
8.3%inclusion25 decks300 decks
1%synergy
Greed
7.7%inclusion23 decks300 decks
1%synergy
Snake Cult Initiation
7.7%inclusion23 decks300 decks
8%synergy
Glistening Oil
6.7%inclusion20 decks300 decks
6%synergy
Alien Symbiosis
5.1%inclusion4 decks79 decks
5%synergy
Corpses of the Lost
5.0%inclusion15 decks300 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
32%inclusion96 decks300 decks
29%synergy
Liliana of the Dark Realms
20%inclusion59 decks300 decks
6%synergy
Utility Lands
Rogue's Passage
64%inclusion193 decks300 decks
45%synergy
Karn's Bastion
56%inclusion169 decks300 decks
52%synergy
Bojuka Bog
42%inclusion127 decks300 decks
-5%synergy
Cabal Coffers
37%inclusion111 decks300 decks
-18%synergy
Cabal Stronghold
27%inclusion81 decks300 decks
-8%synergy
Inkmoth Nexus
21%inclusion64 decks300 decks
20%synergy
Shizo, Death's Storehouse
20%inclusion61 decks300 decks
10%synergy
Urborg, Tomb of Yawgmoth
19%inclusion57 decks300 decks
-19%synergy
Cathedral of War
18%inclusion55 decks300 decks
18%synergy
Witch's Cottage
13%inclusion40 decks300 decks
-11%synergy
War Room
12%inclusion37 decks300 decks
-4%synergy
Castle Locthwain
11%inclusion34 decks300 decks
-6%synergy
Temple of the False God
11%inclusion33 decks300 decks
3%synergy
Nykthos, Shrine to Nyx
10%inclusion30 decks300 decks
-20%synergy
Reliquary Tower
10%inclusion29 decks300 decks
-21%synergy
The Black Gate
9.0%inclusion27 decks300 decks
6%synergy
Mortuary Mire
8.7%inclusion26 decks300 decks
-4%synergy
Barren Moor
8.7%inclusion26 decks300 decks
-1%synergy
Command Beacon
7.0%inclusion21 decks300 decks
-1%synergy
Minas Morgul, Dark Fortress
7.0%inclusion21 decks300 decks
4%synergy
Access Tunnel
5.3%inclusion16 decks300 decks
2%synergy
Buried Ruin
5.0%inclusion15 decks300 decks
0%synergy
Mana Artifacts
Sol Ring
83%inclusion250 decks300 decks
-3%synergy
Arcane Signet
61%inclusion184 decks300 decks
-1%synergy
Charcoal Diamond
42%inclusion125 decks300 decks
19%synergy
Mind Stone
38%inclusion113 decks300 decks
8%synergy
Glistening Sphere
32%inclusion95 decks300 decks
30%synergy
Heraldic Banner
20%inclusion61 decks300 decks
15%synergy
Caged Sun
17%inclusion51 decks300 decks
6%synergy
Staff of Compleation
15%inclusion46 decks300 decks
14%synergy
Fellwar Stone
15%inclusion46 decks300 decks
1%synergy
Thought Vessel
14%inclusion43 decks300 decks
-11%synergy
Gilded Lotus
14%inclusion42 decks300 decks
9%synergy
Commander's Sphere
14%inclusion41 decks300 decks
5%synergy
Everflowing Chalice
11%inclusion33 decks300 decks
5%synergy
Thran Dynamo
11%inclusion33 decks300 decks
5%synergy
Worn Powerstone
11%inclusion33 decks300 decks
7%synergy
Throne of Eldraine
7.3%inclusion22 decks300 decks
-3%synergy
Sceptre of Eternal Glory
6.3%inclusion19 decks300 decks
-2%synergy
Hedron Archive
5.7%inclusion17 decks300 decks
2%synergy
Lands
Swamp
98%inclusion293 decks300 decks
3%synergy
Myriad Landscape
28%inclusion83 decks300 decks
2%synergy
Malakir Rebirth
15%inclusion44 decks300 decks
-8%synergy
Mirrex
12%inclusion36 decks300 decks
11%synergy
Opal Palace
10%inclusion30 decks300 decks
9%synergy
Fell the Profane
10%inclusion27 decks279 decks
-9%synergy
Command Tower
5.7%inclusion17 decks300 decks
0%synergy
The Seedcore
5.3%inclusion16 decks300 decks
5%synergy
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