Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #795
45decks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Pox Plague
20%inclusion2 decks10 decks
15%synergy
Masterful Flourish
10%inclusion1 decks10 decks
9%synergy
High Synergy Cards
Plague Stinger
80%inclusion36 decks45 decks
79%synergy
Plague Myr
76%inclusion34 decks45 decks
74%synergy
Hand of the Praetors
71%inclusion32 decks45 decks
70%synergy
Infectious Inquiry
71%inclusion32 decks45 decks
68%synergy
Blightbelly Rat
69%inclusion31 decks45 decks
65%synergy
Drown in Ichor
69%inclusion31 decks45 decks
65%synergy
Ichorclaw Myr
64%inclusion29 decks45 decks
64%synergy
Ichor Rats
67%inclusion30 decks45 decks
64%synergy
Core Prowler
62%inclusion28 decks45 decks
62%synergy
Whispering Specter
62%inclusion28 decks45 decks
62%synergy
Top Cards
Lashwrithe
64%inclusion29 decks45 decks
61%synergy
Vraska's Fall
64%inclusion29 decks45 decks
61%synergy
Feed the Swarm
62%inclusion28 decks45 decks
12%synergy
Phyrexian Crusader
62%inclusion28 decks45 decks
61%synergy
Bilious Skulldweller
60%inclusion27 decks45 decks
59%synergy
Reaper of Sheoldred
58%inclusion26 decks45 decks
57%synergy
Corpse Cur
58%inclusion26 decks45 decks
57%synergy
Swiftfoot Boots
58%inclusion26 decks45 decks
26%synergy
Phyrexian Arena
58%inclusion26 decks45 decks
18%synergy
Flensermite
56%inclusion25 decks45 decks
55%synergy
Creatures
Crypt Ghast
56%inclusion25 decks45 decks
8%synergy
Pestilent Syphoner
47%inclusion21 decks45 decks
46%synergy
Flesh-Eater Imp
44%inclusion20 decks45 decks
44%synergy
Septic Rats
44%inclusion20 decks45 decks
43%synergy
Myr Convert
40%inclusion18 decks45 decks
39%synergy
Phyrexian Obliterator
38%inclusion17 decks45 decks
27%synergy
Phyrexian Juggernaut
33%inclusion15 decks45 decks
33%synergy
Necropede
33%inclusion15 decks45 decks
33%synergy
K'rrik, Son of Yawgmoth
31%inclusion14 decks45 decks
12%synergy
Leaden Myr
31%inclusion14 decks45 decks
25%synergy
Solemn Simulacrum
29%inclusion13 decks45 decks
7%synergy
Gulping Scraptrap
27%inclusion12 decks45 decks
26%synergy
Contagious Nim
24%inclusion11 decks45 decks
24%synergy
Yawgmoth, Thran Physician
22%inclusion10 decks45 decks
12%synergy
Blightsteel Colossus
20%inclusion9 decks45 decks
19%synergy
Dread Presence
18%inclusion8 decks45 decks
4%synergy
Swamp Mosquito
18%inclusion8 decks45 decks
18%synergy
Blackcleave Goblin
16%inclusion7 decks45 decks
15%synergy
Gray Merchant of Asphodel
16%inclusion7 decks45 decks
-35%synergy
Sheoldred's Headcleaver
16%inclusion7 decks45 decks
15%synergy
Vector Asp
13%inclusion6 decks45 decks
13%synergy
Magus of the Coffers
13%inclusion6 decks45 decks
7%synergy
Necroskitter
13%inclusion6 decks45 decks
10%synergy
Brass Squire
13%inclusion6 decks45 decks
13%synergy
Nirkana Revenant
13%inclusion6 decks45 decks
2%synergy
Burnished Hart
13%inclusion6 decks45 decks
6%synergy
Toxic Nim
13%inclusion6 decks45 decks
13%synergy
Silent Arbiter
11%inclusion5 decks45 decks
10%synergy
Defiler of Flesh
11%inclusion5 decks45 decks
7%synergy
Palladium Myr
11%inclusion5 decks45 decks
9%synergy
Sheoldred, Whispering One
11%inclusion5 decks45 decks
0%synergy
Massacre Girl, Known Killer
11%inclusion5 decks45 decks
8%synergy
Dark Confidant
8.9%inclusion4 decks45 decks
1%synergy
Grafted Butcher
8.9%inclusion4 decks45 decks
9%synergy
Scheming Aspirant
8.9%inclusion4 decks45 decks
9%synergy
Phyrexian Vatmother
8.9%inclusion4 decks45 decks
9%synergy
Nimraiser Paladin
8.9%inclusion4 decks45 decks
9%synergy
Gwenom, Remorseless
7.7%inclusion2 decks26 decks
4%synergy
Zenos yae Galvus
6.9%inclusion2 decks29 decks
3%synergy
Hullcarver
6.9%inclusion2 decks29 decks
6%synergy
Paragon of Open Graves
6.7%inclusion3 decks45 decks
6%synergy
Dune Mover
6.7%inclusion3 decks45 decks
7%synergy
Phyrexian Digester
6.7%inclusion3 decks45 decks
7%synergy
Suspicious Bookcase
6.7%inclusion3 decks45 decks
6%synergy
Scavenger Regent
5.9%inclusion2 decks34 decks
5%synergy
Qarsi Revenant
5.9%inclusion2 decks34 decks
1%synergy
Madame Null, Power Broker
5.6%inclusion1 decks18 decks
5%synergy
Rat King, Verminister
5.6%inclusion1 decks18 decks
2%synergy
Instants
Dark Ritual
56%inclusion25 decks45 decks
-11%synergy
Defile
53%inclusion24 decks45 decks
17%synergy
Howl from Beyond
49%inclusion22 decks45 decks
48%synergy
Tainted Strike
49%inclusion22 decks45 decks
46%synergy
Whisper of the Dross
47%inclusion21 decks45 decks
44%synergy
Grim Affliction
47%inclusion21 decks45 decks
45%synergy
Go for the Throat
36%inclusion16 decks45 decks
13%synergy
Withering Torment
30%inclusion13 decks43 decks
-1%synergy
Imp's Mischief
29%inclusion13 decks45 decks
4%synergy
Dismember
27%inclusion12 decks45 decks
16%synergy
Virulent Wound
24%inclusion11 decks45 decks
24%synergy
Snuff Out
22%inclusion10 decks45 decks
9%synergy
Doom Blade
22%inclusion10 decks45 decks
15%synergy
Infernal Grasp
22%inclusion10 decks45 decks
-3%synergy
Malakir Rebirth
20%inclusion9 decks45 decks
-3%synergy
Sugar Rush
18%inclusion8 decks45 decks
17%synergy
Murder
18%inclusion8 decks45 decks
8%synergy
Archenemy's Charm
17%inclusion5 decks29 decks
8%synergy
Hero's Downfall
16%inclusion7 decks45 decks
9%synergy
Anoint with Affliction
16%inclusion7 decks45 decks
15%synergy
Unlikely Aid
16%inclusion7 decks45 decks
15%synergy
Astarion's Thirst
13%inclusion6 decks45 decks
12%synergy
Force of Despair
13%inclusion6 decks45 decks
6%synergy
Unnatural Endurance
13%inclusion6 decks45 decks
13%synergy
Supernatural Stamina
13%inclusion6 decks45 decks
6%synergy
Consuming Corruption
11%inclusion5 decks45 decks
-5%synergy
Lash of Thorns
11%inclusion5 decks45 decks
11%synergy
Withering Boon
11%inclusion5 decks45 decks
7%synergy
Undying Malice
11%inclusion5 decks45 decks
1%synergy
Tragic Slip
11%inclusion5 decks45 decks
-9%synergy
Fell the Profane
8.9%inclusion4 decks45 decks
-10%synergy
Grotesque Mutation
8.9%inclusion4 decks45 decks
9%synergy
Cabal Ritual
8.9%inclusion4 decks45 decks
-9%synergy
Rush of Vitality
8.9%inclusion4 decks45 decks
8%synergy
Darkness
8.9%inclusion4 decks45 decks
-1%synergy
Professor's Warning
8.9%inclusion4 decks45 decks
8%synergy
Deadly Rollick
6.7%inclusion3 decks45 decks
-18%synergy
Geth's Verdict
6.7%inclusion3 decks45 decks
6%synergy
Sheoldred's Edict
6.7%inclusion3 decks45 decks
-8%synergy
Hatred
6.7%inclusion3 decks45 decks
6%synergy
Grasp of Darkness
6.7%inclusion3 decks45 decks
5%synergy
Culling the Weak
6.7%inclusion3 decks45 decks
-10%synergy
Armor of Shadows
6.7%inclusion3 decks45 decks
4%synergy
Vampire's Bite
6.7%inclusion3 decks45 decks
7%synergy
Baleful Mastery
6.7%inclusion3 decks45 decks
-2%synergy
Maximum Overdrive
5.7%inclusion2 decks35 decks
5%synergy
Sorceries
Phyresis Outbreak
53%inclusion24 decks45 decks
52%synergy
Sign in Blood
49%inclusion22 decks45 decks
14%synergy
Crux of Fate
42%inclusion19 decks45 decks
41%synergy
Night's Whisper
42%inclusion19 decks45 decks
17%synergy
Caress of Phyrexia
40%inclusion18 decks45 decks
39%synergy
Read the Bones
33%inclusion15 decks45 decks
17%synergy
Vat Emergence
31%inclusion14 decks45 decks
30%synergy
Reanimate
22%inclusion10 decks45 decks
-18%synergy
Toxic Deluge
22%inclusion10 decks45 decks
-15%synergy
Mutilate
20%inclusion9 decks45 decks
3%synergy
Spread the Sickness
18%inclusion8 decks45 decks
17%synergy
Diabolic Tutor
18%inclusion8 decks45 decks
4%synergy
Geth's Summons
18%inclusion8 decks45 decks
17%synergy
Exsanguinate
16%inclusion7 decks45 decks
-9%synergy
In Garruk's Wake
16%inclusion7 decks45 decks
12%synergy
Black Sun's Zenith
13%inclusion6 decks45 decks
8%synergy
Feed the Infection
13%inclusion6 decks45 decks
13%synergy
Bubbling Muck
11%inclusion5 decks45 decks
-4%synergy
Ancient Craving
11%inclusion5 decks45 decks
9%synergy
Innocent Blood
8.9%inclusion4 decks45 decks
3%synergy
Ambition's Cost
8.9%inclusion4 decks45 decks
6%synergy
Syphon Mind
8.9%inclusion4 decks45 decks
-3%synergy
Blasphemous Edict
7.5%inclusion3 decks40 decks
-9%synergy
Praetor's Grasp
6.7%inclusion3 decks45 decks
3%synergy
Nighthaze
6.7%inclusion3 decks45 decks
6%synergy
Corrupt
6.7%inclusion3 decks45 decks
4%synergy
Bloodline Bidding
5.0%inclusion1 decks20 decks
1%synergy
Utility Artifacts
Blackblade Reforged
56%inclusion25 decks45 decks
53%synergy
Contagion Clasp
44%inclusion20 decks45 decks
42%synergy
Nightmare Lash
42%inclusion19 decks45 decks
40%synergy
Fireshrieker
42%inclusion19 decks45 decks
40%synergy
Jet Medallion
42%inclusion19 decks45 decks
-20%synergy
Whispersilk Cloak
38%inclusion17 decks45 decks
32%synergy
Trailblazer's Boots
31%inclusion14 decks45 decks
29%synergy
Champion's Helm
31%inclusion14 decks45 decks
29%synergy
Lightning Greaves
29%inclusion13 decks45 decks
-5%synergy
Wayfarer's Bauble
27%inclusion12 decks45 decks
12%synergy
Contagion Engine
27%inclusion12 decks45 decks
25%synergy
Hero's Blade
27%inclusion12 decks45 decks
26%synergy
The Darkness Crystal
21%inclusion6 decks29 decks
1%synergy
Strata Scythe
18%inclusion8 decks45 decks
17%synergy
Commander's Plate
18%inclusion8 decks45 decks
12%synergy
Sword of Vengeance
18%inclusion8 decks45 decks
17%synergy
Leyline Axe
18%inclusion7 decks40 decks
17%synergy
Throne of Geth
16%inclusion7 decks45 decks
15%synergy
Inquisitor's Flail
16%inclusion7 decks45 decks
15%synergy
Loxodon Warhammer
16%inclusion7 decks45 decks
14%synergy
Brotherhood Regalia
16%inclusion7 decks45 decks
13%synergy
Nettlecyst
13%inclusion6 decks45 decks
13%synergy
Darksteel Plate
13%inclusion6 decks45 decks
11%synergy
Sword of the Animist
13%inclusion6 decks45 decks
10%synergy
Prowler's Helm
11%inclusion5 decks45 decks
10%synergy
Vorpal Sword
11%inclusion5 decks45 decks
7%synergy
Sword of Truth and Justice
11%inclusion5 decks45 decks
10%synergy
Grafted Exoskeleton
11%inclusion5 decks45 decks
10%synergy
Genji Glove
10%inclusion3 decks29 decks
9%synergy
Manifold Key
8.9%inclusion4 decks45 decks
7%synergy
Thran Power Suit
8.9%inclusion4 decks45 decks
9%synergy
O-Naginata
8.9%inclusion4 decks45 decks
9%synergy
Cranial Plating
8.9%inclusion4 decks45 decks
6%synergy
Expedition Map
8.9%inclusion4 decks45 decks
-3%synergy
Shadowspear
8.9%inclusion4 decks45 decks
5%synergy
Bontu's Monument
8.9%inclusion4 decks45 decks
-20%synergy
Silver Shroud Costume
8.9%inclusion4 decks45 decks
8%synergy
Pact Weapon
8.9%inclusion4 decks45 decks
7%synergy
Adaptive Omnitool
8.3%inclusion3 decks36 decks
8%synergy
Bloodthorn Flail
6.7%inclusion3 decks45 decks
7%synergy
Pip-Boy 3000
6.7%inclusion3 decks45 decks
6%synergy
Mind Carver
6.7%inclusion3 decks45 decks
7%synergy
Prosthetic Injector
6.7%inclusion3 decks45 decks
6%synergy
Mask of Avacyn
6.7%inclusion3 decks45 decks
6%synergy
Bladed Battle-Fan
6.7%inclusion3 decks45 decks
6%synergy
Decimator Web
6.7%inclusion3 decks45 decks
7%synergy
Basilisk Collar
6.7%inclusion3 decks45 decks
4%synergy
Ring of Xathrid
6.7%inclusion3 decks45 decks
6%synergy
Hammer of Nazahn
6.7%inclusion3 decks45 decks
6%synergy
Quick-Draw Katana
5.3%inclusion2 decks38 decks
5%synergy
Enchantments
Necrogen Communion
51%inclusion23 decks45 decks
49%synergy
Kaya's Ghostform
29%inclusion13 decks45 decks
19%synergy
Unspeakable Symbol
24%inclusion11 decks45 decks
24%synergy
Bad Moon
24%inclusion11 decks45 decks
21%synergy
Phyresis
20%inclusion9 decks45 decks
18%synergy
Fungal Fortitude
16%inclusion7 decks45 decks
14%synergy
Relic Putrescence
13%inclusion6 decks45 decks
13%synergy
Glistening Oil
11%inclusion5 decks45 decks
10%synergy
Dauthi Embrace
11%inclusion5 decks45 decks
9%synergy
Demonic Embrace
11%inclusion5 decks45 decks
10%synergy
Endless Scream
11%inclusion5 decks45 decks
11%synergy
Black Market Connections
11%inclusion5 decks45 decks
-13%synergy
Black Market
8.9%inclusion4 decks45 decks
-12%synergy
Shade's Form
8.9%inclusion4 decks45 decks
8%synergy
Demonic Vigor
6.7%inclusion3 decks45 decks
6%synergy
Phyrexian Scriptures
6.7%inclusion3 decks45 decks
5%synergy
Greed
6.7%inclusion3 decks45 decks
0%synergy
Underworld Connections
6.7%inclusion3 decks45 decks
5%synergy
Necrosynthesis
6.7%inclusion3 decks45 decks
6%synergy
Eternal Thirst
6.7%inclusion3 decks45 decks
4%synergy
Snake Cult Initiation
6.7%inclusion3 decks45 decks
7%synergy
No Mercy
6.7%inclusion3 decks45 decks
-1%synergy
Oubliette
6.7%inclusion3 decks45 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
38%inclusion17 decks45 decks
35%synergy
Liliana of the Dark Realms
24%inclusion11 decks45 decks
10%synergy
Utility Lands
Rogue's Passage
58%inclusion26 decks45 decks
39%synergy
Karn's Bastion
51%inclusion23 decks45 decks
47%synergy
Bojuka Bog
42%inclusion19 decks45 decks
-5%synergy
Cabal Coffers
40%inclusion18 decks45 decks
-15%synergy
Inkmoth Nexus
36%inclusion16 decks45 decks
35%synergy
Cabal Stronghold
27%inclusion12 decks45 decks
-8%synergy
Cathedral of War
22%inclusion10 decks45 decks
22%synergy
Shizo, Death's Storehouse
20%inclusion9 decks45 decks
10%synergy
Witch's Cottage
20%inclusion9 decks45 decks
-5%synergy
Barren Moor
18%inclusion8 decks45 decks
8%synergy
Nykthos, Shrine to Nyx
18%inclusion8 decks45 decks
-12%synergy
Mortuary Mire
16%inclusion7 decks45 decks
2%synergy
War Room
16%inclusion7 decks45 decks
0%synergy
Urborg, Tomb of Yawgmoth
11%inclusion5 decks45 decks
-26%synergy
Castle Locthwain
11%inclusion5 decks45 decks
-6%synergy
Phyrexian Tower
8.9%inclusion4 decks45 decks
-17%synergy
Command Beacon
8.9%inclusion4 decks45 decks
1%synergy
Reliquary Tower
8.9%inclusion4 decks45 decks
-21%synergy
Secret Tunnel
8.3%inclusion2 decks24 decks
7%synergy
Vault of Whispers
6.7%inclusion3 decks45 decks
1%synergy
Ghost Quarter
6.7%inclusion3 decks45 decks
4%synergy
Buried Ruin
6.7%inclusion3 decks45 decks
2%synergy
The Dross Pits
6.7%inclusion3 decks45 decks
5%synergy
Temple of the False God
6.7%inclusion3 decks45 decks
-1%synergy
Mana Artifacts
Sol Ring
84%inclusion38 decks45 decks
-1%synergy
Arcane Signet
67%inclusion30 decks45 decks
5%synergy
Charcoal Diamond
42%inclusion19 decks45 decks
20%synergy
Glistening Sphere
38%inclusion17 decks45 decks
37%synergy
Mind Stone
24%inclusion11 decks45 decks
-4%synergy
Staff of Compleation
22%inclusion10 decks45 decks
21%synergy
Caged Sun
18%inclusion8 decks45 decks
7%synergy
Heraldic Banner
16%inclusion7 decks45 decks
10%synergy
Everflowing Chalice
11%inclusion5 decks45 decks
6%synergy
Fellwar Stone
11%inclusion5 decks45 decks
-3%synergy
Worn Powerstone
11%inclusion5 decks45 decks
7%synergy
Hedron Archive
8.9%inclusion4 decks45 decks
5%synergy
Thought Vessel
8.9%inclusion4 decks45 decks
-16%synergy
Commander's Sphere
6.7%inclusion3 decks45 decks
-2%synergy
Throne of Eldraine
6.7%inclusion3 decks45 decks
-3%synergy
Gilded Lotus
6.7%inclusion3 decks45 decks
1%synergy
Star Compass
6.7%inclusion3 decks45 decks
6%synergy
Wickersmith's Tools
5.0%inclusion1 decks20 decks
5%synergy
Lands
Swamp
100%inclusion45 decks45 decks
5%synergy
Myriad Landscape
33%inclusion15 decks45 decks
8%synergy
Malakir Rebirth
20%inclusion9 decks45 decks
-3%synergy
Mirrex
18%inclusion8 decks45 decks
17%synergy
Fell the Profane
8.9%inclusion4 decks45 decks
-10%synergy
The Seedcore
8.9%inclusion4 decks45 decks
9%synergy
Opal Palace
6.7%inclusion3 decks45 decks
6%synergy
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