Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
41decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
73%inclusion30 decks41 decks
72%synergy
Plague Myr
71%inclusion29 decks41 decks
69%synergy
Infectious Inquiry
68%inclusion28 decks41 decks
65%synergy
Hand of the Praetors
66%inclusion27 decks41 decks
65%synergy
Lashwrithe
68%inclusion28 decks41 decks
64%synergy
Drown in Ichor
66%inclusion27 decks41 decks
62%synergy
Vraska's Fall
63%inclusion26 decks41 decks
60%synergy
Ichorclaw Myr
59%inclusion24 decks41 decks
58%synergy
Ichor Rats
61%inclusion25 decks41 decks
58%synergy
Phyrexian Crusader
59%inclusion24 decks41 decks
58%synergy
Top Cards
Feed the Swarm
61%inclusion25 decks41 decks
10%synergy
Swiftfoot Boots
61%inclusion25 decks41 decks
29%synergy
Crypt Ghast
59%inclusion24 decks41 decks
11%synergy
Blightbelly Rat
59%inclusion24 decks41 decks
55%synergy
Dark Ritual
56%inclusion23 decks41 decks
-10%synergy
Corpse Cur
56%inclusion23 decks41 decks
56%synergy
Core Prowler
54%inclusion22 decks41 decks
53%synergy
Whispering Specter
54%inclusion22 decks41 decks
53%synergy
Defile
54%inclusion22 decks41 decks
17%synergy
Bilious Skulldweller
54%inclusion22 decks41 decks
53%synergy
Creatures
Reaper of Sheoldred
51%inclusion21 decks41 decks
51%synergy
Flensermite
49%inclusion20 decks41 decks
48%synergy
Septic Rats
41%inclusion17 decks41 decks
40%synergy
Flesh-Eater Imp
39%inclusion16 decks41 decks
38%synergy
Pestilent Syphoner
37%inclusion15 decks41 decks
36%synergy
Myr Convert
37%inclusion15 decks41 decks
36%synergy
Solemn Simulacrum
34%inclusion14 decks41 decks
12%synergy
Phyrexian Obliterator
34%inclusion14 decks41 decks
23%synergy
Necropede
34%inclusion14 decks41 decks
34%synergy
Phyrexian Juggernaut
27%inclusion11 decks41 decks
27%synergy
Leaden Myr
27%inclusion11 decks41 decks
21%synergy
K'rrik, Son of Yawgmoth
24%inclusion10 decks41 decks
5%synergy
Contagious Nim
22%inclusion9 decks41 decks
22%synergy
Gulping Scraptrap
22%inclusion9 decks41 decks
21%synergy
Dread Presence
20%inclusion8 decks41 decks
5%synergy
Yawgmoth, Thran Physician
20%inclusion8 decks41 decks
9%synergy
Gray Merchant of Asphodel
17%inclusion7 decks41 decks
-34%synergy
Swamp Mosquito
17%inclusion7 decks41 decks
17%synergy
Silent Arbiter
15%inclusion6 decks41 decks
13%synergy
Magus of the Coffers
15%inclusion6 decks41 decks
8%synergy
Defiler of Flesh
15%inclusion6 decks41 decks
11%synergy
Nirkana Revenant
15%inclusion6 decks41 decks
3%synergy
Burnished Hart
15%inclusion6 decks41 decks
7%synergy
Sheoldred's Headcleaver
15%inclusion6 decks41 decks
14%synergy
Massacre Girl, Known Killer
15%inclusion6 decks41 decks
11%synergy
Blightsteel Colossus
15%inclusion6 decks41 decks
14%synergy
Blackcleave Goblin
12%inclusion5 decks41 decks
12%synergy
Vector Asp
12%inclusion5 decks41 decks
12%synergy
Dark Confidant
12%inclusion5 decks41 decks
5%synergy
Necroskitter
12%inclusion5 decks41 decks
9%synergy
Brass Squire
12%inclusion5 decks41 decks
12%synergy
Grafted Butcher
12%inclusion5 decks41 decks
12%synergy
Sheoldred, Whispering One
12%inclusion5 decks41 decks
0%synergy
Palladium Myr
10%inclusion4 decks41 decks
8%synergy
Toxic Nim
10%inclusion4 decks41 decks
10%synergy
Nimraiser Paladin
10%inclusion4 decks41 decks
10%synergy
Feral Deathgorger
7.7%inclusion2 decks26 decks
7%synergy
Scavenger Regent
7.7%inclusion2 decks26 decks
7%synergy
Qarsi Revenant
7.7%inclusion2 decks26 decks
3%synergy
Dune Mover
7.3%inclusion3 decks41 decks
7%synergy
Paragon of Open Graves
7.3%inclusion3 decks41 decks
7%synergy
Massacre Girl
7.3%inclusion3 decks41 decks
0%synergy
Massacre Wurm
7.3%inclusion3 decks41 decks
-10%synergy
Phyrexian Digester
7.3%inclusion3 decks41 decks
7%synergy
Suspicious Bookcase
7.3%inclusion3 decks41 decks
7%synergy
Scheming Aspirant
7.3%inclusion3 decks41 decks
7%synergy
Phyrexian Vatmother
7.3%inclusion3 decks41 decks
7%synergy
Agent Venom
6.7%inclusion1 decks15 decks
4%synergy
Swarm, Being of Bees
6.7%inclusion1 decks15 decks
6%synergy
Venomized Cat
6.7%inclusion1 decks15 decks
6%synergy
Instants
Howl from Beyond
49%inclusion20 decks41 decks
48%synergy
Grim Affliction
46%inclusion19 decks41 decks
44%synergy
Tainted Strike
41%inclusion17 decks41 decks
38%synergy
Whisper of the Dross
39%inclusion16 decks41 decks
36%synergy
Go for the Throat
32%inclusion13 decks41 decks
9%synergy
Withering Torment
28%inclusion10 decks36 decks
-4%synergy
Imp's Mischief
27%inclusion11 decks41 decks
2%synergy
Virulent Wound
27%inclusion11 decks41 decks
26%synergy
Dismember
27%inclusion11 decks41 decks
16%synergy
Sugar Rush
24%inclusion10 decks41 decks
24%synergy
Doom Blade
22%inclusion9 decks41 decks
15%synergy
Supernatural Stamina
22%inclusion9 decks41 decks
14%synergy
Infernal Grasp
22%inclusion9 decks41 decks
-3%synergy
Malakir Rebirth
22%inclusion9 decks41 decks
-1%synergy
Snuff Out
20%inclusion8 decks41 decks
7%synergy
Hero's Downfall
17%inclusion7 decks41 decks
10%synergy
Anoint with Affliction
17%inclusion7 decks41 decks
16%synergy
Unlikely Aid
17%inclusion7 decks41 decks
16%synergy
Murder
17%inclusion7 decks41 decks
7%synergy
Consuming Corruption
15%inclusion6 decks39 decks
0%synergy
Astarion's Thirst
15%inclusion6 decks41 decks
13%synergy
Force of Despair
15%inclusion6 decks41 decks
7%synergy
Undying Malice
15%inclusion6 decks41 decks
5%synergy
Tragic Slip
12%inclusion5 decks41 decks
-8%synergy
Fell the Profane
10%inclusion4 decks39 decks
-9%synergy
Grotesque Mutation
10%inclusion4 decks41 decks
10%synergy
Unnatural Endurance
10%inclusion4 decks41 decks
9%synergy
Armor of Shadows
10%inclusion4 decks41 decks
7%synergy
Withering Boon
10%inclusion4 decks41 decks
5%synergy
Sudden Spoiling
10%inclusion4 decks41 decks
1%synergy
Professor's Warning
10%inclusion4 decks41 decks
8%synergy
Sheoldred's Edict
7.3%inclusion3 decks41 decks
-7%synergy
Hatred
7.3%inclusion3 decks41 decks
6%synergy
Grasp of Darkness
7.3%inclusion3 decks41 decks
5%synergy
Cabal Ritual
7.3%inclusion3 decks41 decks
-11%synergy
Lash of Thorns
7.3%inclusion3 decks41 decks
7%synergy
Rush of Vitality
7.3%inclusion3 decks41 decks
7%synergy
Darkness
7.3%inclusion3 decks41 decks
-3%synergy
Baleful Mastery
7.3%inclusion3 decks41 decks
-2%synergy
Offer Immortality
7.3%inclusion3 decks41 decks
5%synergy
Scorpion's Sting
5.9%inclusion1 decks17 decks
6%synergy
Archenemy's Charm
5.6%inclusion1 decks18 decks
-3%synergy
Sorceries
Phyresis Outbreak
51%inclusion21 decks41 decks
49%synergy
Sign in Blood
46%inclusion19 decks41 decks
11%synergy
Night's Whisper
41%inclusion17 decks41 decks
17%synergy
Caress of Phyrexia
37%inclusion15 decks41 decks
36%synergy
Read the Bones
34%inclusion14 decks41 decks
17%synergy
Crux of Fate
32%inclusion13 decks41 decks
30%synergy
Vat Emergence
27%inclusion11 decks41 decks
25%synergy
Spread the Sickness
24%inclusion10 decks41 decks
24%synergy
Diabolic Tutor
24%inclusion10 decks41 decks
10%synergy
Mutilate
24%inclusion10 decks41 decks
7%synergy
Toxic Deluge
24%inclusion10 decks41 decks
-12%synergy
Black Sun's Zenith
20%inclusion8 decks41 decks
14%synergy
In Garruk's Wake
17%inclusion7 decks41 decks
13%synergy
Bubbling Muck
15%inclusion6 decks41 decks
-1%synergy
Feed the Infection
15%inclusion6 decks41 decks
14%synergy
Exsanguinate
15%inclusion6 decks41 decks
-10%synergy
Reanimate
15%inclusion6 decks41 decks
-25%synergy
Geth's Summons
15%inclusion6 decks41 decks
14%synergy
Ancient Craving
10%inclusion4 decks41 decks
8%synergy
Ambition's Cost
10%inclusion4 decks41 decks
7%synergy
Blasphemous Edict
9.1%inclusion3 decks33 decks
-8%synergy
Insatiable Avarice
7.5%inclusion3 decks40 decks
-4%synergy
Extinction Event
7.3%inclusion3 decks41 decks
7%synergy
Profane Tutor
7.3%inclusion3 decks41 decks
3%synergy
Agadeem's Awakening
7.3%inclusion3 decks41 decks
0%synergy
Syphon Mind
7.3%inclusion3 decks41 decks
-5%synergy
Nighthaze
7.3%inclusion3 decks41 decks
7%synergy
Prison Break
6.7%inclusion1 decks15 decks
6%synergy
Risky Research
5.9%inclusion1 decks17 decks
5%synergy
Lethal Protection
5.9%inclusion1 decks17 decks
6%synergy
Venom's Hunger
5.9%inclusion1 decks17 decks
6%synergy
Final Vengeance
5.6%inclusion2 decks36 decks
4%synergy
Utility Artifacts
Blackblade Reforged
54%inclusion22 decks41 decks
51%synergy
Fireshrieker
49%inclusion20 decks41 decks
47%synergy
Nightmare Lash
46%inclusion19 decks41 decks
44%synergy
Contagion Clasp
44%inclusion18 decks41 decks
42%synergy
Jet Medallion
41%inclusion17 decks41 decks
-20%synergy
Wayfarer's Bauble
34%inclusion14 decks41 decks
19%synergy
Whispersilk Cloak
34%inclusion14 decks41 decks
28%synergy
Lightning Greaves
32%inclusion13 decks41 decks
-2%synergy
Contagion Engine
29%inclusion12 decks41 decks
27%synergy
Trailblazer's Boots
29%inclusion12 decks41 decks
27%synergy
Champion's Helm
29%inclusion12 decks41 decks
27%synergy
Hero's Blade
29%inclusion12 decks41 decks
29%synergy
Nettlecyst
20%inclusion8 decks41 decks
19%synergy
Strata Scythe
20%inclusion8 decks41 decks
19%synergy
Leyline Axe
18%inclusion6 decks33 decks
17%synergy
Throne of Geth
17%inclusion7 decks41 decks
17%synergy
Cranial Plating
17%inclusion7 decks41 decks
14%synergy
Inquisitor's Flail
17%inclusion7 decks41 decks
17%synergy
Commander's Plate
17%inclusion7 decks41 decks
11%synergy
Loxodon Warhammer
17%inclusion7 decks41 decks
16%synergy
Sword of Vengeance
17%inclusion7 decks41 decks
16%synergy
Expedition Map
15%inclusion6 decks41 decks
3%synergy
The Darkness Crystal
14%inclusion3 decks21 decks
-6%synergy
Brotherhood Regalia
13%inclusion5 decks39 decks
10%synergy
Manifold Key
12%inclusion5 decks41 decks
10%synergy
Prowler's Helm
12%inclusion5 decks41 decks
11%synergy
Sword of Truth and Justice
12%inclusion5 decks41 decks
11%synergy
Sword of the Animist
12%inclusion5 decks41 decks
8%synergy
Thran Power Suit
10%inclusion4 decks41 decks
9%synergy
Shadowspear
10%inclusion4 decks41 decks
6%synergy
Livewire Lash
10%inclusion4 decks41 decks
10%synergy
Silver Shroud Costume
10%inclusion4 decks41 decks
9%synergy
Darksteel Plate
10%inclusion4 decks41 decks
8%synergy
Pact Weapon
10%inclusion4 decks41 decks
8%synergy
Hammer of Nazahn
10%inclusion4 decks41 decks
9%synergy
Basilisk Collar
10%inclusion4 decks41 decks
7%synergy
Genji Glove
10%inclusion2 decks21 decks
8%synergy
Bloodthorn Flail
7.3%inclusion3 decks41 decks
7%synergy
Viridian Claw
7.3%inclusion3 decks41 decks
7%synergy
Pip-Boy 3000
7.3%inclusion3 decks41 decks
7%synergy
Armillary Sphere
7.3%inclusion3 decks41 decks
7%synergy
Whip of Erebos
7.3%inclusion3 decks41 decks
-3%synergy
Vorpal Sword
7.3%inclusion3 decks41 decks
3%synergy
Mind Carver
7.3%inclusion3 decks41 decks
7%synergy
Heirloom Blade
7.3%inclusion3 decks41 decks
7%synergy
Prosthetic Injector
7.3%inclusion3 decks41 decks
7%synergy
Bontu's Monument
7.3%inclusion3 decks41 decks
-21%synergy
Strider Harness
7.3%inclusion3 decks41 decks
7%synergy
Ring of Xathrid
7.3%inclusion3 decks41 decks
7%synergy
Grafted Exoskeleton
7.3%inclusion3 decks41 decks
6%synergy
Enchantments
Phyrexian Arena
46%inclusion19 decks41 decks
6%synergy
Necrogen Communion
39%inclusion16 decks41 decks
37%synergy
Kaya's Ghostform
34%inclusion14 decks41 decks
24%synergy
Unspeakable Symbol
24%inclusion10 decks41 decks
23%synergy
Bad Moon
22%inclusion9 decks41 decks
19%synergy
Fungal Fortitude
20%inclusion8 decks41 decks
18%synergy
Phyresis
17%inclusion7 decks41 decks
15%synergy
Relic Putrescence
15%inclusion6 decks41 decks
14%synergy
Greed
10%inclusion4 decks41 decks
3%synergy
Glistening Oil
10%inclusion4 decks41 decks
9%synergy
Dauthi Embrace
10%inclusion4 decks41 decks
8%synergy
Endless Scream
10%inclusion4 decks41 decks
10%synergy
Demonic Embrace
10%inclusion4 decks41 decks
9%synergy
Black Market Connections
10%inclusion4 decks41 decks
-14%synergy
Demonic Vigor
7.3%inclusion3 decks41 decks
7%synergy
Phyrexian Scriptures
7.3%inclusion3 decks41 decks
6%synergy
Black Market
7.3%inclusion3 decks41 decks
-14%synergy
Underworld Connections
7.3%inclusion3 decks41 decks
5%synergy
Shade's Form
7.3%inclusion3 decks41 decks
7%synergy
Eternal Thirst
7.3%inclusion3 decks41 decks
5%synergy
Alien Symbiosis
6.7%inclusion1 decks15 decks
6%synergy
Super State
5.6%inclusion1 decks18 decks
5%synergy
Planeswalkers
Vraska, Betrayal's Sting
34%inclusion14 decks41 decks
31%synergy
Liliana of the Dark Realms
20%inclusion8 decks41 decks
5%synergy
Utility Lands
Rogue's Passage
56%inclusion23 decks41 decks
37%synergy
Karn's Bastion
49%inclusion20 decks41 decks
45%synergy
Cabal Coffers
44%inclusion18 decks41 decks
-11%synergy
Bojuka Bog
39%inclusion16 decks41 decks
-8%synergy
Inkmoth Nexus
34%inclusion14 decks41 decks
33%synergy
Cabal Stronghold
32%inclusion13 decks41 decks
-3%synergy
Cathedral of War
27%inclusion11 decks41 decks
26%synergy
Shizo, Death's Storehouse
22%inclusion9 decks41 decks
12%synergy
War Room
20%inclusion8 decks41 decks
3%synergy
Barren Moor
17%inclusion7 decks41 decks
7%synergy
Witch's Cottage
17%inclusion7 decks41 decks
-8%synergy
Nykthos, Shrine to Nyx
17%inclusion7 decks41 decks
-13%synergy
Urborg, Tomb of Yawgmoth
17%inclusion7 decks41 decks
-20%synergy
Castle Locthwain
15%inclusion6 decks41 decks
-3%synergy
Mortuary Mire
12%inclusion5 decks41 decks
-1%synergy
Command Beacon
12%inclusion5 decks41 decks
4%synergy
Phyrexian Tower
10%inclusion4 decks41 decks
-15%synergy
Secret Tunnel
7.7%inclusion1 decks13 decks
6%synergy
Buried Ruin
7.3%inclusion3 decks41 decks
2%synergy
The Black Gate
7.3%inclusion3 decks41 decks
4%synergy
The Dross Pits
7.3%inclusion3 decks41 decks
6%synergy
Polluted Mire
7.3%inclusion3 decks41 decks
4%synergy
Temple of the False God
7.3%inclusion3 decks41 decks
-1%synergy
Mana Artifacts
Sol Ring
85%inclusion35 decks41 decks
-1%synergy
Arcane Signet
66%inclusion27 decks41 decks
4%synergy
Charcoal Diamond
41%inclusion17 decks41 decks
19%synergy
Glistening Sphere
37%inclusion15 decks41 decks
35%synergy
Staff of Compleation
24%inclusion10 decks41 decks
23%synergy
Heraldic Banner
24%inclusion10 decks41 decks
19%synergy
Mind Stone
24%inclusion10 decks41 decks
-5%synergy
Caged Sun
22%inclusion9 decks41 decks
10%synergy
Fellwar Stone
15%inclusion6 decks41 decks
0%synergy
Thought Vessel
12%inclusion5 decks41 decks
-14%synergy
Worn Powerstone
12%inclusion5 decks41 decks
8%synergy
Commander's Sphere
10%inclusion4 decks41 decks
1%synergy
Hedron Archive
10%inclusion4 decks41 decks
6%synergy
Everflowing Chalice
7.3%inclusion3 decks41 decks
2%synergy
Throne of Eldraine
7.3%inclusion3 decks41 decks
-3%synergy
Gilded Lotus
7.3%inclusion3 decks41 decks
2%synergy
The Soul Stone
6.3%inclusion1 decks16 decks
-8%synergy
Lands
Swamp
100%inclusion41 decks41 decks
5%synergy
Myriad Landscape
34%inclusion14 decks41 decks
8%synergy
Mirrex
22%inclusion9 decks41 decks
21%synergy
Malakir Rebirth
22%inclusion9 decks41 decks
-1%synergy
Fell the Profane
10%inclusion4 decks39 decks
-9%synergy
Opal Palace
10%inclusion4 decks41 decks
9%synergy
The Seedcore
7.3%inclusion3 decks41 decks
7%synergy
Agadeem's Awakening
7.3%inclusion3 decks41 decks
0%synergy
Daily Bugle Building
6.7%inclusion1 decks15 decks
6%synergy
Urza's Cave
5.1%inclusion2 decks39 decks
-3%synergy
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