Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #794
42decks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Madame Null, Power Broker
6.7%inclusion1 decks15 decks
6%synergy
Rat King, Verminister
6.7%inclusion1 decks15 decks
4%synergy
High Synergy Cards
Plague Stinger
81%inclusion34 decks42 decks
80%synergy
Plague Myr
76%inclusion32 decks42 decks
75%synergy
Hand of the Praetors
71%inclusion30 decks42 decks
71%synergy
Infectious Inquiry
71%inclusion30 decks42 decks
69%synergy
Blightbelly Rat
71%inclusion30 decks42 decks
68%synergy
Drown in Ichor
69%inclusion29 decks42 decks
65%synergy
Core Prowler
64%inclusion27 decks42 decks
64%synergy
Ichor Rats
67%inclusion28 decks42 decks
64%synergy
Phyrexian Crusader
64%inclusion27 decks42 decks
63%synergy
Vraska's Fall
67%inclusion28 decks42 decks
63%synergy
Top Cards
Lashwrithe
67%inclusion28 decks42 decks
63%synergy
Whispering Specter
62%inclusion26 decks42 decks
61%synergy
Feed the Swarm
62%inclusion26 decks42 decks
11%synergy
Bilious Skulldweller
62%inclusion26 decks42 decks
61%synergy
Ichorclaw Myr
62%inclusion26 decks42 decks
61%synergy
Reaper of Sheoldred
60%inclusion25 decks42 decks
59%synergy
Corpse Cur
60%inclusion25 decks42 decks
59%synergy
Crypt Ghast
60%inclusion25 decks42 decks
12%synergy
Swiftfoot Boots
57%inclusion24 decks42 decks
26%synergy
Phyrexian Arena
57%inclusion24 decks42 decks
17%synergy
Creatures
Flensermite
55%inclusion23 decks42 decks
54%synergy
Pestilent Syphoner
48%inclusion20 decks42 decks
47%synergy
Septic Rats
45%inclusion19 decks42 decks
43%synergy
Flesh-Eater Imp
43%inclusion18 decks42 decks
42%synergy
Myr Convert
40%inclusion17 decks42 decks
40%synergy
Phyrexian Obliterator
38%inclusion16 decks42 decks
27%synergy
Leaden Myr
33%inclusion14 decks42 decks
27%synergy
Phyrexian Juggernaut
31%inclusion13 decks42 decks
31%synergy
Solemn Simulacrum
31%inclusion13 decks42 decks
9%synergy
K'rrik, Son of Yawgmoth
31%inclusion13 decks42 decks
12%synergy
Necropede
31%inclusion13 decks42 decks
31%synergy
Contagious Nim
26%inclusion11 decks42 decks
26%synergy
Gulping Scraptrap
26%inclusion11 decks42 decks
26%synergy
Yawgmoth, Thran Physician
21%inclusion9 decks42 decks
11%synergy
Blightsteel Colossus
21%inclusion9 decks42 decks
21%synergy
Dread Presence
17%inclusion7 decks42 decks
3%synergy
Gray Merchant of Asphodel
17%inclusion7 decks42 decks
-34%synergy
Swamp Mosquito
17%inclusion7 decks42 decks
17%synergy
Sheoldred's Headcleaver
17%inclusion7 decks42 decks
16%synergy
Blackcleave Goblin
14%inclusion6 decks42 decks
14%synergy
Magus of the Coffers
14%inclusion6 decks42 decks
8%synergy
Brass Squire
14%inclusion6 decks42 decks
14%synergy
Nirkana Revenant
14%inclusion6 decks42 decks
3%synergy
Burnished Hart
14%inclusion6 decks42 decks
7%synergy
Sheoldred, Whispering One
14%inclusion6 decks42 decks
3%synergy
Vector Asp
12%inclusion5 decks42 decks
12%synergy
Silent Arbiter
12%inclusion5 decks42 decks
11%synergy
Defiler of Flesh
12%inclusion5 decks42 decks
8%synergy
Necroskitter
12%inclusion5 decks42 decks
9%synergy
Palladium Myr
12%inclusion5 decks42 decks
10%synergy
Toxic Nim
12%inclusion5 decks42 decks
12%synergy
Dark Confidant
10%inclusion4 decks42 decks
2%synergy
Grafted Butcher
10%inclusion4 decks42 decks
9%synergy
Massacre Girl, Known Killer
10%inclusion4 decks42 decks
6%synergy
Scheming Aspirant
10%inclusion4 decks42 decks
9%synergy
Nimraiser Paladin
10%inclusion4 decks42 decks
9%synergy
Phyrexian Vatmother
10%inclusion4 decks42 decks
9%synergy
Gwenom, Remorseless
8.7%inclusion2 decks23 decks
5%synergy
Zenos yae Galvus
7.7%inclusion2 decks26 decks
4%synergy
Dune Mover
7.1%inclusion3 decks42 decks
7%synergy
Paragon of Open Graves
7.1%inclusion3 decks42 decks
6%synergy
Phyrexian Digester
7.1%inclusion3 decks42 decks
7%synergy
Suspicious Bookcase
7.1%inclusion3 decks42 decks
7%synergy
Scavenger Regent
6.5%inclusion2 decks31 decks
6%synergy
Qarsi Revenant
6.5%inclusion2 decks31 decks
1%synergy
Unstoppable Slasher
5.0%inclusion2 decks40 decks
-1%synergy
Instants
Defile
55%inclusion23 decks42 decks
18%synergy
Dark Ritual
55%inclusion23 decks42 decks
-12%synergy
Whisper of the Dross
48%inclusion20 decks42 decks
45%synergy
Grim Affliction
48%inclusion20 decks42 decks
46%synergy
Howl from Beyond
48%inclusion20 decks42 decks
47%synergy
Tainted Strike
45%inclusion19 decks42 decks
42%synergy
Go for the Throat
36%inclusion15 decks42 decks
13%synergy
Withering Torment
30%inclusion12 decks40 decks
-1%synergy
Imp's Mischief
29%inclusion12 decks42 decks
4%synergy
Dismember
29%inclusion12 decks42 decks
18%synergy
Virulent Wound
26%inclusion11 decks42 decks
26%synergy
Snuff Out
21%inclusion9 decks42 decks
8%synergy
Doom Blade
21%inclusion9 decks42 decks
14%synergy
Infernal Grasp
21%inclusion9 decks42 decks
-4%synergy
Malakir Rebirth
21%inclusion9 decks42 decks
-1%synergy
Sugar Rush
19%inclusion8 decks42 decks
19%synergy
Murder
19%inclusion8 decks42 decks
9%synergy
Hero's Downfall
17%inclusion7 decks42 decks
10%synergy
Anoint with Affliction
17%inclusion7 decks42 decks
16%synergy
Unlikely Aid
17%inclusion7 decks42 decks
16%synergy
Archenemy's Charm
15%inclusion4 decks26 decks
7%synergy
Force of Despair
14%inclusion6 decks42 decks
7%synergy
Unnatural Endurance
14%inclusion6 decks42 decks
14%synergy
Supernatural Stamina
14%inclusion6 decks42 decks
7%synergy
Astarion's Thirst
12%inclusion5 decks42 decks
10%synergy
Consuming Corruption
12%inclusion5 decks42 decks
-4%synergy
Withering Boon
12%inclusion5 decks42 decks
7%synergy
Undying Malice
12%inclusion5 decks42 decks
2%synergy
Tragic Slip
12%inclusion5 decks42 decks
-8%synergy
Fell the Profane
10%inclusion4 decks42 decks
-9%synergy
Grotesque Mutation
10%inclusion4 decks42 decks
9%synergy
Lash of Thorns
10%inclusion4 decks42 decks
9%synergy
Rush of Vitality
10%inclusion4 decks42 decks
9%synergy
Darkness
10%inclusion4 decks42 decks
0%synergy
Professor's Warning
10%inclusion4 decks42 decks
8%synergy
Geth's Verdict
7.1%inclusion3 decks42 decks
7%synergy
Sheoldred's Edict
7.1%inclusion3 decks42 decks
-8%synergy
Hatred
7.1%inclusion3 decks42 decks
6%synergy
Grasp of Darkness
7.1%inclusion3 decks42 decks
5%synergy
Cabal Ritual
7.1%inclusion3 decks42 decks
-11%synergy
Armor of Shadows
7.1%inclusion3 decks42 decks
5%synergy
Vampire's Bite
7.1%inclusion3 decks42 decks
7%synergy
Baleful Mastery
7.1%inclusion3 decks42 decks
-1%synergy
Maximum Overdrive
6.3%inclusion2 decks32 decks
5%synergy
Sorceries
Phyresis Outbreak
55%inclusion23 decks42 decks
53%synergy
Sign in Blood
50%inclusion21 decks42 decks
15%synergy
Crux of Fate
40%inclusion17 decks42 decks
39%synergy
Night's Whisper
40%inclusion17 decks42 decks
16%synergy
Caress of Phyrexia
40%inclusion17 decks42 decks
40%synergy
Vat Emergence
33%inclusion14 decks42 decks
32%synergy
Read the Bones
33%inclusion14 decks42 decks
16%synergy
Reanimate
24%inclusion10 decks42 decks
-16%synergy
Mutilate
21%inclusion9 decks42 decks
4%synergy
Toxic Deluge
21%inclusion9 decks42 decks
-15%synergy
Spread the Sickness
19%inclusion8 decks42 decks
18%synergy
Geth's Summons
19%inclusion8 decks42 decks
19%synergy
Diabolic Tutor
17%inclusion7 decks42 decks
2%synergy
Exsanguinate
17%inclusion7 decks42 decks
-8%synergy
In Garruk's Wake
17%inclusion7 decks42 decks
13%synergy
Feed the Infection
14%inclusion6 decks42 decks
14%synergy
Black Sun's Zenith
12%inclusion5 decks42 decks
6%synergy
Ancient Craving
12%inclusion5 decks42 decks
10%synergy
Bubbling Muck
10%inclusion4 decks42 decks
-6%synergy
Innocent Blood
10%inclusion4 decks42 decks
4%synergy
Ambition's Cost
10%inclusion4 decks42 decks
7%synergy
Blasphemous Edict
8.1%inclusion3 decks37 decks
-8%synergy
Syphon Mind
7.1%inclusion3 decks42 decks
-5%synergy
Nighthaze
7.1%inclusion3 decks42 decks
7%synergy
Bloodline Bidding
5.9%inclusion1 decks17 decks
1%synergy
Final Vengeance
5.0%inclusion2 decks40 decks
3%synergy
Utility Artifacts
Blackblade Reforged
57%inclusion24 decks42 decks
54%synergy
Contagion Clasp
45%inclusion19 decks42 decks
43%synergy
Jet Medallion
45%inclusion19 decks42 decks
-17%synergy
Nightmare Lash
43%inclusion18 decks42 decks
41%synergy
Fireshrieker
43%inclusion18 decks42 decks
41%synergy
Whispersilk Cloak
36%inclusion15 decks42 decks
30%synergy
Trailblazer's Boots
31%inclusion13 decks42 decks
29%synergy
Champion's Helm
31%inclusion13 decks42 decks
29%synergy
Wayfarer's Bauble
29%inclusion12 decks42 decks
13%synergy
Lightning Greaves
29%inclusion12 decks42 decks
-5%synergy
Hero's Blade
29%inclusion12 decks42 decks
28%synergy
Contagion Engine
26%inclusion11 decks42 decks
24%synergy
The Darkness Crystal
19%inclusion5 decks26 decks
-1%synergy
Strata Scythe
19%inclusion8 decks42 decks
18%synergy
Commander's Plate
19%inclusion8 decks42 decks
13%synergy
Throne of Geth
17%inclusion7 decks42 decks
16%synergy
Inquisitor's Flail
17%inclusion7 decks42 decks
16%synergy
Loxodon Warhammer
17%inclusion7 decks42 decks
15%synergy
Sword of Vengeance
17%inclusion7 decks42 decks
16%synergy
Leyline Axe
16%inclusion6 decks37 decks
15%synergy
Nettlecyst
14%inclusion6 decks42 decks
14%synergy
Darksteel Plate
14%inclusion6 decks42 decks
12%synergy
Brotherhood Regalia
14%inclusion6 decks42 decks
12%synergy
Vorpal Sword
12%inclusion5 decks42 decks
8%synergy
Sword of Truth and Justice
12%inclusion5 decks42 decks
11%synergy
Sword of the Animist
12%inclusion5 decks42 decks
8%synergy
Genji Glove
12%inclusion3 decks26 decks
10%synergy
Manifold Key
10%inclusion4 decks42 decks
8%synergy
Thran Power Suit
10%inclusion4 decks42 decks
9%synergy
Prowler's Helm
10%inclusion4 decks42 decks
9%synergy
Cranial Plating
10%inclusion4 decks42 decks
6%synergy
Shadowspear
10%inclusion4 decks42 decks
6%synergy
Expedition Map
10%inclusion4 decks42 decks
-2%synergy
Bontu's Monument
10%inclusion4 decks42 decks
-19%synergy
Pact Weapon
10%inclusion4 decks42 decks
7%synergy
Silver Shroud Costume
10%inclusion4 decks42 decks
8%synergy
Grafted Exoskeleton
10%inclusion4 decks42 decks
8%synergy
Bloodthorn Flail
7.1%inclusion3 decks42 decks
7%synergy
Pip-Boy 3000
7.1%inclusion3 decks42 decks
7%synergy
O-Naginata
7.1%inclusion3 decks42 decks
7%synergy
Mind Carver
7.1%inclusion3 decks42 decks
7%synergy
Prosthetic Injector
7.1%inclusion3 decks42 decks
7%synergy
Mask of Avacyn
7.1%inclusion3 decks42 decks
6%synergy
Ring of Xathrid
7.1%inclusion3 decks42 decks
6%synergy
Basilisk Collar
7.1%inclusion3 decks42 decks
4%synergy
Hammer of Nazahn
7.1%inclusion3 decks42 decks
6%synergy
Adaptive Omnitool
6.1%inclusion2 decks33 decks
6%synergy
Quick-Draw Katana
5.7%inclusion2 decks35 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion21 decks42 decks
48%synergy
Kaya's Ghostform
29%inclusion12 decks42 decks
19%synergy
Unspeakable Symbol
26%inclusion11 decks42 decks
25%synergy
Bad Moon
26%inclusion11 decks42 decks
23%synergy
Phyresis
19%inclusion8 decks42 decks
17%synergy
Fungal Fortitude
17%inclusion7 decks42 decks
15%synergy
Relic Putrescence
14%inclusion6 decks42 decks
14%synergy
Glistening Oil
12%inclusion5 decks42 decks
11%synergy
Dauthi Embrace
12%inclusion5 decks42 decks
10%synergy
Endless Scream
12%inclusion5 decks42 decks
12%synergy
Demonic Embrace
12%inclusion5 decks42 decks
11%synergy
Black Market Connections
12%inclusion5 decks42 decks
-12%synergy
Black Market
10%inclusion4 decks42 decks
-11%synergy
Shade's Form
10%inclusion4 decks42 decks
9%synergy
Demonic Vigor
7.1%inclusion3 decks42 decks
7%synergy
Phyrexian Scriptures
7.1%inclusion3 decks42 decks
6%synergy
Greed
7.1%inclusion3 decks42 decks
0%synergy
Underworld Connections
7.1%inclusion3 decks42 decks
5%synergy
Eternal Thirst
7.1%inclusion3 decks42 decks
5%synergy
Snake Cult Initiation
7.1%inclusion3 decks42 decks
7%synergy
No Mercy
7.1%inclusion3 decks42 decks
0%synergy
Mornsong Aria
5.6%inclusion1 decks18 decks
4%synergy
Planeswalkers
Vraska, Betrayal's Sting
36%inclusion15 decks42 decks
33%synergy
Liliana of the Dark Realms
24%inclusion10 decks42 decks
10%synergy
Utility Lands
Rogue's Passage
57%inclusion24 decks42 decks
38%synergy
Karn's Bastion
50%inclusion21 decks42 decks
46%synergy
Bojuka Bog
43%inclusion18 decks42 decks
-4%synergy
Cabal Coffers
40%inclusion17 decks42 decks
-14%synergy
Inkmoth Nexus
36%inclusion15 decks42 decks
35%synergy
Cabal Stronghold
29%inclusion12 decks42 decks
-6%synergy
Shizo, Death's Storehouse
21%inclusion9 decks42 decks
11%synergy
Cathedral of War
21%inclusion9 decks42 decks
21%synergy
Barren Moor
19%inclusion8 decks42 decks
9%synergy
Witch's Cottage
19%inclusion8 decks42 decks
-6%synergy
Nykthos, Shrine to Nyx
19%inclusion8 decks42 decks
-11%synergy
Mortuary Mire
14%inclusion6 decks42 decks
1%synergy
War Room
14%inclusion6 decks42 decks
-2%synergy
Castle Locthwain
12%inclusion5 decks42 decks
-5%synergy
Phyrexian Tower
10%inclusion4 decks42 decks
-16%synergy
Command Beacon
10%inclusion4 decks42 decks
1%synergy
Urborg, Tomb of Yawgmoth
10%inclusion4 decks42 decks
-28%synergy
Secret Tunnel
10%inclusion2 decks21 decks
8%synergy
Buried Ruin
7.1%inclusion3 decks42 decks
2%synergy
Ghost Quarter
7.1%inclusion3 decks42 decks
4%synergy
The Dross Pits
7.1%inclusion3 decks42 decks
6%synergy
Reliquary Tower
7.1%inclusion3 decks42 decks
-23%synergy
Temple of the False God
7.1%inclusion3 decks42 decks
-1%synergy
Mana Artifacts
Sol Ring
86%inclusion36 decks42 decks
0%synergy
Arcane Signet
67%inclusion28 decks42 decks
5%synergy
Charcoal Diamond
43%inclusion18 decks42 decks
21%synergy
Glistening Sphere
40%inclusion17 decks42 decks
39%synergy
Staff of Compleation
24%inclusion10 decks42 decks
22%synergy
Mind Stone
21%inclusion9 decks42 decks
-8%synergy
Caged Sun
19%inclusion8 decks42 decks
8%synergy
Heraldic Banner
17%inclusion7 decks42 decks
11%synergy
Everflowing Chalice
12%inclusion5 decks42 decks
6%synergy
Worn Powerstone
12%inclusion5 decks42 decks
8%synergy
Hedron Archive
10%inclusion4 decks42 decks
6%synergy
Fellwar Stone
10%inclusion4 decks42 decks
-5%synergy
Commander's Sphere
7.1%inclusion3 decks42 decks
-1%synergy
Throne of Eldraine
7.1%inclusion3 decks42 decks
-3%synergy
Thought Vessel
7.1%inclusion3 decks42 decks
-18%synergy
Gilded Lotus
7.1%inclusion3 decks42 decks
2%synergy
Star Compass
7.1%inclusion3 decks42 decks
6%synergy
Lands
Swamp
100%inclusion42 decks42 decks
5%synergy
Myriad Landscape
33%inclusion14 decks42 decks
8%synergy
Malakir Rebirth
21%inclusion9 decks42 decks
-1%synergy
Mirrex
19%inclusion8 decks42 decks
18%synergy
Fell the Profane
10%inclusion4 decks42 decks
-9%synergy
The Seedcore
10%inclusion4 decks42 decks
9%synergy
Opal Palace
7.1%inclusion3 decks42 decks
6%synergy
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