Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #794
49decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Plague Stinger
78%inclusion38 decks49 decks
77%synergy
Hand of the Praetors
71%inclusion35 decks49 decks
71%synergy
Plague Myr
71%inclusion35 decks49 decks
70%synergy
Infectious Inquiry
69%inclusion34 decks49 decks
67%synergy
Ichor Rats
65%inclusion32 decks49 decks
62%synergy
Drown in Ichor
65%inclusion32 decks49 decks
62%synergy
Ichorclaw Myr
61%inclusion30 decks49 decks
61%synergy
Vraska's Fall
63%inclusion31 decks49 decks
60%synergy
Blightbelly Rat
63%inclusion31 decks49 decks
60%synergy
Lashwrithe
63%inclusion31 decks49 decks
59%synergy
Top Cards
Feed the Swarm
63%inclusion31 decks49 decks
13%synergy
Dark Ritual
61%inclusion30 decks49 decks
-6%synergy
Whispering Specter
59%inclusion29 decks49 decks
59%synergy
Swiftfoot Boots
59%inclusion29 decks49 decks
28%synergy
Bilious Skulldweller
57%inclusion28 decks49 decks
56%synergy
Phyrexian Crusader
57%inclusion28 decks49 decks
56%synergy
Core Prowler
57%inclusion28 decks49 decks
57%synergy
Blackblade Reforged
55%inclusion27 decks49 decks
52%synergy
Crypt Ghast
55%inclusion27 decks49 decks
8%synergy
Corpse Cur
55%inclusion27 decks49 decks
55%synergy
Creatures
Reaper of Sheoldred
53%inclusion26 decks49 decks
52%synergy
Flensermite
51%inclusion25 decks49 decks
51%synergy
Pestilent Syphoner
45%inclusion22 decks49 decks
44%synergy
Flesh-Eater Imp
41%inclusion20 decks49 decks
40%synergy
Myr Convert
39%inclusion19 decks49 decks
38%synergy
Septic Rats
39%inclusion19 decks49 decks
37%synergy
Phyrexian Obliterator
37%inclusion18 decks49 decks
26%synergy
Phyrexian Juggernaut
33%inclusion16 decks49 decks
32%synergy
K'rrik, Son of Yawgmoth
33%inclusion16 decks49 decks
13%synergy
Necropede
33%inclusion16 decks49 decks
32%synergy
Leaden Myr
33%inclusion16 decks49 decks
27%synergy
Solemn Simulacrum
29%inclusion14 decks49 decks
7%synergy
Gulping Scraptrap
24%inclusion12 decks49 decks
24%synergy
Contagious Nim
22%inclusion11 decks49 decks
22%synergy
Yawgmoth, Thran Physician
22%inclusion11 decks49 decks
13%synergy
Blightsteel Colossus
18%inclusion9 decks49 decks
18%synergy
Blackcleave Goblin
16%inclusion8 decks49 decks
16%synergy
Dread Presence
16%inclusion8 decks49 decks
3%synergy
Gray Merchant of Asphodel
16%inclusion8 decks49 decks
-34%synergy
Swamp Mosquito
16%inclusion8 decks49 decks
16%synergy
Brass Squire
14%inclusion7 decks49 decks
14%synergy
Burnished Hart
14%inclusion7 decks49 decks
7%synergy
Vector Asp
12%inclusion6 decks49 decks
12%synergy
Palladium Myr
12%inclusion6 decks49 decks
11%synergy
Sheoldred's Headcleaver
12%inclusion6 decks49 decks
12%synergy
Silent Arbiter
10%inclusion5 decks49 decks
9%synergy
Dark Confidant
10%inclusion5 decks49 decks
2%synergy
Magus of the Coffers
10%inclusion5 decks49 decks
4%synergy
Defiler of Flesh
10%inclusion5 decks49 decks
6%synergy
Necroskitter
10%inclusion5 decks49 decks
7%synergy
Nirkana Revenant
10%inclusion5 decks49 decks
-0%synergy
Sheoldred, Whispering One
10%inclusion5 decks49 decks
-1%synergy
Toxic Nim
10%inclusion5 decks49 decks
10%synergy
Nimraiser Paladin
10%inclusion5 decks49 decks
10%synergy
Massacre Girl, Known Killer
10%inclusion5 decks49 decks
7%synergy
Ornithopter of Paradise
8.2%inclusion4 decks49 decks
5%synergy
Grafted Butcher
8.2%inclusion4 decks49 decks
8%synergy
Scheming Aspirant
8.2%inclusion4 decks49 decks
8%synergy
Phyrexian Vatmother
8.2%inclusion4 decks49 decks
8%synergy
Scavenger Regent
7.9%inclusion3 decks38 decks
7%synergy
Dune Mover
6.1%inclusion3 decks49 decks
6%synergy
Paragon of Open Graves
6.1%inclusion3 decks49 decks
5%synergy
Skinrender
6.1%inclusion3 decks49 decks
5%synergy
Suspicious Bookcase
6.1%inclusion3 decks49 decks
6%synergy
Blood Pet
6.1%inclusion3 decks49 decks
-2%synergy
Zenos yae Galvus
6.1%inclusion2 decks33 decks
3%synergy
Hullcarver
6.1%inclusion2 decks33 decks
5%synergy
Surge Conductor
6.1%inclusion2 decks33 decks
6%synergy
Qarsi Revenant
5.3%inclusion2 decks38 decks
0%synergy
Instants
Defile
53%inclusion26 decks49 decks
18%synergy
Howl from Beyond
51%inclusion25 decks49 decks
50%synergy
Tainted Strike
47%inclusion23 decks49 decks
44%synergy
Whisper of the Dross
45%inclusion22 decks49 decks
42%synergy
Grim Affliction
45%inclusion22 decks49 decks
43%synergy
Go for the Throat
33%inclusion16 decks49 decks
10%synergy
Withering Torment
30%inclusion14 decks47 decks
-2%synergy
Imp's Mischief
24%inclusion12 decks49 decks
-1%synergy
Dismember
24%inclusion12 decks49 decks
14%synergy
Virulent Wound
22%inclusion11 decks49 decks
22%synergy
Infernal Grasp
22%inclusion11 decks49 decks
-3%synergy
Archenemy's Charm
21%inclusion7 decks33 decks
12%synergy
Doom Blade
20%inclusion10 decks49 decks
13%synergy
Snuff Out
18%inclusion9 decks49 decks
5%synergy
Murder
18%inclusion9 decks49 decks
9%synergy
Anoint with Affliction
16%inclusion8 decks49 decks
16%synergy
Sugar Rush
16%inclusion8 decks49 decks
16%synergy
Malakir Rebirth
16%inclusion8 decks49 decks
-7%synergy
Astarion's Thirst
14%inclusion7 decks49 decks
13%synergy
Hero's Downfall
14%inclusion7 decks49 decks
8%synergy
Supernatural Stamina
14%inclusion7 decks49 decks
7%synergy
Unlikely Aid
14%inclusion7 decks49 decks
14%synergy
Unnatural Endurance
12%inclusion6 decks49 decks
12%synergy
Force of Despair
10%inclusion5 decks49 decks
3%synergy
Consuming Corruption
10%inclusion5 decks49 decks
-5%synergy
Hatred
10%inclusion5 decks49 decks
9%synergy
Cabal Ritual
10%inclusion5 decks49 decks
-8%synergy
Culling the Weak
10%inclusion5 decks49 decks
-7%synergy
Lash of Thorns
10%inclusion5 decks49 decks
10%synergy
Withering Boon
10%inclusion5 decks49 decks
6%synergy
Rush of Vitality
10%inclusion5 decks49 decks
9%synergy
Undying Malice
10%inclusion5 decks49 decks
0%synergy
Tragic Slip
10%inclusion5 decks49 decks
-9%synergy
Fell the Profane
8.2%inclusion4 decks49 decks
-11%synergy
Grotesque Mutation
8.2%inclusion4 decks49 decks
8%synergy
Undying Evil
8.2%inclusion4 decks49 decks
5%synergy
Grasp of Darkness
8.2%inclusion4 decks49 decks
6%synergy
Darkness
8.2%inclusion4 decks49 decks
-2%synergy
Professor's Warning
8.2%inclusion4 decks49 decks
7%synergy
Masterful Flourish
6.7%inclusion1 decks15 decks
5%synergy
Deadly Rollick
6.1%inclusion3 decks49 decks
-19%synergy
Geth's Verdict
6.1%inclusion3 decks49 decks
6%synergy
Sheoldred's Edict
6.1%inclusion3 decks49 decks
-9%synergy
Village Rites
6.1%inclusion3 decks49 decks
-19%synergy
Deadly Dispute
6.1%inclusion3 decks49 decks
-21%synergy
Armor of Shadows
6.1%inclusion3 decks49 decks
4%synergy
Vampire's Bite
6.1%inclusion3 decks49 decks
6%synergy
Fake Your Own Death
6.1%inclusion3 decks49 decks
-1%synergy
Baleful Mastery
6.1%inclusion3 decks49 decks
-2%synergy
Maximum Overdrive
5.1%inclusion2 decks39 decks
4%synergy
Sorceries
Phyresis Outbreak
51%inclusion25 decks49 decks
49%synergy
Sign in Blood
51%inclusion25 decks49 decks
16%synergy
Night's Whisper
45%inclusion22 decks49 decks
20%synergy
Crux of Fate
41%inclusion20 decks49 decks
39%synergy
Caress of Phyrexia
39%inclusion19 decks49 decks
38%synergy
Read the Bones
33%inclusion16 decks49 decks
17%synergy
Vat Emergence
31%inclusion15 decks49 decks
29%synergy
Toxic Deluge
22%inclusion11 decks49 decks
-14%synergy
Mutilate
20%inclusion10 decks49 decks
5%synergy
Reanimate
20%inclusion10 decks49 decks
-20%synergy
Spread the Sickness
18%inclusion9 decks49 decks
18%synergy
Diabolic Tutor
18%inclusion9 decks49 decks
5%synergy
Geth's Summons
18%inclusion9 decks49 decks
18%synergy
Bubbling Muck
16%inclusion8 decks49 decks
1%synergy
In Garruk's Wake
16%inclusion8 decks49 decks
13%synergy
Feed the Infection
14%inclusion7 decks49 decks
14%synergy
Exsanguinate
14%inclusion7 decks49 decks
-10%synergy
Pox Plague
13%inclusion2 decks15 decks
8%synergy
Black Sun's Zenith
10%inclusion5 decks49 decks
5%synergy
Ancient Craving
10%inclusion5 decks49 decks
8%synergy
Blasphemous Edict
9.1%inclusion4 decks44 decks
-7%synergy
Innocent Blood
8.2%inclusion4 decks49 decks
2%synergy
Ambition's Cost
8.2%inclusion4 decks49 decks
5%synergy
Syphon Mind
8.2%inclusion4 decks49 decks
-4%synergy
Praetor's Grasp
6.1%inclusion3 decks49 decks
2%synergy
Corrupt
6.1%inclusion3 decks49 decks
4%synergy
Nighthaze
6.1%inclusion3 decks49 decks
6%synergy
Damnation
6.1%inclusion3 decks49 decks
-14%synergy
Utility Artifacts
Contagion Clasp
45%inclusion22 decks49 decks
43%synergy
Fireshrieker
45%inclusion22 decks49 decks
43%synergy
Jet Medallion
43%inclusion21 decks49 decks
-19%synergy
Nightmare Lash
41%inclusion20 decks49 decks
39%synergy
Whispersilk Cloak
37%inclusion18 decks49 decks
31%synergy
Champion's Helm
35%inclusion17 decks49 decks
32%synergy
Trailblazer's Boots
31%inclusion15 decks49 decks
28%synergy
Contagion Engine
29%inclusion14 decks49 decks
27%synergy
Lightning Greaves
27%inclusion13 decks49 decks
-7%synergy
Hero's Blade
27%inclusion13 decks49 decks
26%synergy
Wayfarer's Bauble
24%inclusion12 decks49 decks
10%synergy
Commander's Plate
18%inclusion9 decks49 decks
12%synergy
Leyline Axe
18%inclusion8 decks44 decks
17%synergy
The Darkness Crystal
18%inclusion6 decks33 decks
-2%synergy
Throne of Geth
16%inclusion8 decks49 decks
16%synergy
Strata Scythe
16%inclusion8 decks49 decks
16%synergy
Sword of the Animist
16%inclusion8 decks49 decks
13%synergy
Loxodon Warhammer
16%inclusion8 decks49 decks
15%synergy
Sword of Vengeance
16%inclusion8 decks49 decks
15%synergy
Inquisitor's Flail
14%inclusion7 decks49 decks
14%synergy
Darksteel Plate
14%inclusion7 decks49 decks
12%synergy
Brotherhood Regalia
14%inclusion7 decks49 decks
12%synergy
Grafted Exoskeleton
14%inclusion7 decks49 decks
13%synergy
Nettlecyst
12%inclusion6 decks49 decks
12%synergy
Sword of Truth and Justice
12%inclusion6 decks49 decks
12%synergy
Expedition Map
12%inclusion6 decks49 decks
1%synergy
Prowler's Helm
10%inclusion5 decks49 decks
9%synergy
Vorpal Sword
10%inclusion5 decks49 decks
6%synergy
Cranial Plating
10%inclusion5 decks49 decks
7%synergy
Silver Shroud Costume
10%inclusion5 decks49 decks
9%synergy
Genji Glove
9.1%inclusion3 decks33 decks
8%synergy
Manifold Key
8.2%inclusion4 decks49 decks
6%synergy
Thran Power Suit
8.2%inclusion4 decks49 decks
8%synergy
O-Naginata
8.2%inclusion4 decks49 decks
8%synergy
Shadowspear
8.2%inclusion4 decks49 decks
4%synergy
Bontu's Monument
8.2%inclusion4 decks49 decks
-20%synergy
Pact Weapon
8.2%inclusion4 decks49 decks
6%synergy
Hammer of Nazahn
8.2%inclusion4 decks49 decks
7%synergy
Adaptive Omnitool
7.5%inclusion3 decks40 decks
7%synergy
Bloodthorn Flail
6.1%inclusion3 decks49 decks
6%synergy
Pip-Boy 3000
6.1%inclusion3 decks49 decks
6%synergy
Whip of Erebos
6.1%inclusion3 decks49 decks
-5%synergy
Skullclamp
6.1%inclusion3 decks49 decks
-16%synergy
Mind Carver
6.1%inclusion3 decks49 decks
6%synergy
Haunted Cloak
6.1%inclusion3 decks49 decks
5%synergy
Prosthetic Injector
6.1%inclusion3 decks49 decks
6%synergy
Helm of the Host
6.1%inclusion3 decks49 decks
5%synergy
Mask of Avacyn
6.1%inclusion3 decks49 decks
5%synergy
Bladed Battle-Fan
6.1%inclusion3 decks49 decks
6%synergy
Ring of Xathrid
6.1%inclusion3 decks49 decks
5%synergy
Enchantments
Phyrexian Arena
55%inclusion27 decks49 decks
16%synergy
Necrogen Communion
51%inclusion25 decks49 decks
49%synergy
Kaya's Ghostform
29%inclusion14 decks49 decks
19%synergy
Unspeakable Symbol
27%inclusion13 decks49 decks
26%synergy
Bad Moon
27%inclusion13 decks49 decks
23%synergy
Phyresis
18%inclusion9 decks49 decks
16%synergy
Relic Putrescence
16%inclusion8 decks49 decks
16%synergy
Fungal Fortitude
16%inclusion8 decks49 decks
15%synergy
Glistening Oil
12%inclusion6 decks49 decks
12%synergy
Greed
10%inclusion5 decks49 decks
4%synergy
Oubliette
10%inclusion5 decks49 decks
7%synergy
Endless Scream
10%inclusion5 decks49 decks
10%synergy
Demonic Embrace
10%inclusion5 decks49 decks
9%synergy
Black Market
8.2%inclusion4 decks49 decks
-12%synergy
Underworld Connections
8.2%inclusion4 decks49 decks
6%synergy
Shade's Form
8.2%inclusion4 decks49 decks
8%synergy
Dauthi Embrace
8.2%inclusion4 decks49 decks
6%synergy
No Mercy
8.2%inclusion4 decks49 decks
1%synergy
Black Market Connections
8.2%inclusion4 decks49 decks
-16%synergy
Demonic Vigor
6.1%inclusion3 decks49 decks
6%synergy
Phyrexian Scriptures
6.1%inclusion3 decks49 decks
5%synergy
Necrosynthesis
6.1%inclusion3 decks49 decks
5%synergy
Eternal Thirst
6.1%inclusion3 decks49 decks
4%synergy
Snake Cult Initiation
6.1%inclusion3 decks49 decks
6%synergy
Planeswalkers
Vraska, Betrayal's Sting
39%inclusion19 decks49 decks
36%synergy
Liliana of the Dark Realms
24%inclusion12 decks49 decks
11%synergy
Utility Lands
Rogue's Passage
59%inclusion29 decks49 decks
40%synergy
Karn's Bastion
53%inclusion26 decks49 decks
49%synergy
Bojuka Bog
45%inclusion22 decks49 decks
-2%synergy
Inkmoth Nexus
37%inclusion18 decks49 decks
36%synergy
Cabal Coffers
37%inclusion18 decks49 decks
-18%synergy
Cabal Stronghold
27%inclusion13 decks49 decks
-8%synergy
Cathedral of War
20%inclusion10 decks49 decks
20%synergy
Witch's Cottage
20%inclusion10 decks49 decks
-4%synergy
Shizo, Death's Storehouse
18%inclusion9 decks49 decks
8%synergy
Barren Moor
18%inclusion9 decks49 decks
9%synergy
Mortuary Mire
16%inclusion8 decks49 decks
3%synergy
War Room
14%inclusion7 decks49 decks
-2%synergy
Nykthos, Shrine to Nyx
14%inclusion7 decks49 decks
-15%synergy
Castle Locthwain
10%inclusion5 decks49 decks
-6%synergy
Urborg, Tomb of Yawgmoth
10%inclusion5 decks49 decks
-27%synergy
Vault of Whispers
8.2%inclusion4 decks49 decks
3%synergy
Phyrexian Tower
8.2%inclusion4 decks49 decks
-18%synergy
Command Beacon
8.2%inclusion4 decks49 decks
-0%synergy
Reliquary Tower
8.2%inclusion4 decks49 decks
-22%synergy
Temple of the False God
8.2%inclusion4 decks49 decks
1%synergy
Ghost Quarter
6.1%inclusion3 decks49 decks
4%synergy
Roadside Reliquary
6.1%inclusion3 decks49 decks
6%synergy
Buried Ruin
6.1%inclusion3 decks49 decks
1%synergy
The Dross Pits
6.1%inclusion3 decks49 decks
5%synergy
Spawning Pool
6.1%inclusion3 decks49 decks
6%synergy
Mana Artifacts
Sol Ring
86%inclusion42 decks49 decks
0%synergy
Arcane Signet
67%inclusion33 decks49 decks
6%synergy
Charcoal Diamond
41%inclusion20 decks49 decks
19%synergy
Glistening Sphere
35%inclusion17 decks49 decks
34%synergy
Mind Stone
29%inclusion14 decks49 decks
0%synergy
Staff of Compleation
24%inclusion12 decks49 decks
23%synergy
Caged Sun
18%inclusion9 decks49 decks
8%synergy
Heraldic Banner
16%inclusion8 decks49 decks
11%synergy
Everflowing Chalice
12%inclusion6 decks49 decks
7%synergy
Fellwar Stone
12%inclusion6 decks49 decks
-2%synergy
Worn Powerstone
12%inclusion6 decks49 decks
8%synergy
Gilded Lotus
10%inclusion5 decks49 decks
5%synergy
Commander's Sphere
8.2%inclusion4 decks49 decks
0%synergy
Hedron Archive
8.2%inclusion4 decks49 decks
5%synergy
Thought Vessel
8.2%inclusion4 decks49 decks
-17%synergy
Gauntlet of Power
6.1%inclusion3 decks49 decks
3%synergy
Thran Dynamo
6.1%inclusion3 decks49 decks
0%synergy
Star Compass
6.1%inclusion3 decks49 decks
5%synergy
Lands
Swamp
100%inclusion49 decks49 decks
5%synergy
Myriad Landscape
35%inclusion17 decks49 decks
10%synergy
Mirrex
20%inclusion10 decks49 decks
20%synergy
Malakir Rebirth
16%inclusion8 decks49 decks
-7%synergy
The Seedcore
10%inclusion5 decks49 decks
10%synergy
Fell the Profane
8.2%inclusion4 decks49 decks
-11%synergy
Urza's Cave
6.1%inclusion3 decks49 decks
-2%synergy
Opal Palace
6.1%inclusion3 decks49 decks
5%synergy
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