Skithiryx, the Blight Dragon (Commander) - Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
39decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Secret Tunnel
11%inclusion1 decks9 decks
10%synergy
High Synergy Cards
Plague Stinger
77%inclusion30 decks39 decks
76%synergy
Plague Myr
74%inclusion29 decks39 decks
73%synergy
Infectious Inquiry
72%inclusion28 decks39 decks
69%synergy
Hand of the Praetors
69%inclusion27 decks39 decks
68%synergy
Lashwrithe
72%inclusion28 decks39 decks
68%synergy
Ichor Rats
67%inclusion26 decks39 decks
64%synergy
Phyrexian Crusader
64%inclusion25 decks39 decks
63%synergy
Drown in Ichor
67%inclusion26 decks39 decks
62%synergy
Ichorclaw Myr
62%inclusion24 decks39 decks
61%synergy
Vraska's Fall
64%inclusion25 decks39 decks
60%synergy
Top Cards
Feed the Swarm
64%inclusion25 decks39 decks
13%synergy
Crypt Ghast
62%inclusion24 decks39 decks
13%synergy
Whispering Specter
59%inclusion23 decks39 decks
58%synergy
Dark Ritual
59%inclusion23 decks39 decks
-8%synergy
Corpse Cur
59%inclusion23 decks39 decks
59%synergy
Blightbelly Rat
59%inclusion23 decks39 decks
55%synergy
Swiftfoot Boots
59%inclusion23 decks39 decks
27%synergy
Core Prowler
56%inclusion22 decks39 decks
56%synergy
Blackblade Reforged
56%inclusion22 decks39 decks
53%synergy
Reaper of Sheoldred
54%inclusion21 decks39 decks
53%synergy
Game Changers
Necropotence
5.1%inclusion2 decks39 decks
-10%synergy
Creatures
Bilious Skulldweller
51%inclusion20 decks39 decks
50%synergy
Flensermite
49%inclusion19 decks39 decks
48%synergy
Flesh-Eater Imp
44%inclusion17 decks39 decks
43%synergy
Septic Rats
41%inclusion16 decks39 decks
39%synergy
Pestilent Syphoner
36%inclusion14 decks39 decks
35%synergy
Myr Convert
36%inclusion14 decks39 decks
35%synergy
Phyrexian Obliterator
33%inclusion13 decks39 decks
22%synergy
Necropede
33%inclusion13 decks39 decks
33%synergy
Solemn Simulacrum
31%inclusion12 decks39 decks
7%synergy
Phyrexian Juggernaut
28%inclusion11 decks39 decks
28%synergy
Leaden Myr
26%inclusion10 decks39 decks
19%synergy
Contagious Nim
23%inclusion9 decks39 decks
23%synergy
Yawgmoth, Thran Physician
23%inclusion9 decks39 decks
13%synergy
K'rrik, Son of Yawgmoth
23%inclusion9 decks39 decks
4%synergy
Gulping Scraptrap
23%inclusion9 decks39 decks
23%synergy
Dread Presence
21%inclusion8 decks39 decks
6%synergy
Gray Merchant of Asphodel
18%inclusion7 decks39 decks
-34%synergy
Swamp Mosquito
18%inclusion7 decks39 decks
18%synergy
Silent Arbiter
15%inclusion6 decks39 decks
14%synergy
Dark Confidant
15%inclusion6 decks39 decks
8%synergy
Defiler of Flesh
15%inclusion6 decks39 decks
11%synergy
Nirkana Revenant
15%inclusion6 decks39 decks
4%synergy
Massacre Girl, Known Killer
15%inclusion6 decks39 decks
12%synergy
Blightsteel Colossus
15%inclusion6 decks39 decks
15%synergy
Blackcleave Goblin
13%inclusion5 decks39 decks
13%synergy
Vector Asp
13%inclusion5 decks39 decks
13%synergy
Magus of the Coffers
13%inclusion5 decks39 decks
6%synergy
Necroskitter
13%inclusion5 decks39 decks
9%synergy
Brass Squire
13%inclusion5 decks39 decks
12%synergy
Grafted Butcher
13%inclusion5 decks39 decks
13%synergy
Burnished Hart
13%inclusion5 decks39 decks
5%synergy
Sheoldred, Whispering One
13%inclusion5 decks39 decks
1%synergy
Sheoldred's Headcleaver
13%inclusion5 decks39 decks
13%synergy
Toxic Nim
10%inclusion4 decks39 decks
10%synergy
Nimraiser Paladin
10%inclusion4 decks39 decks
10%synergy
Phyrexian Vatmother
10%inclusion4 decks39 decks
10%synergy
Agent Venom
9.1%inclusion1 decks11 decks
7%synergy
Dune Mover
7.7%inclusion3 decks39 decks
8%synergy
Paragon of Open Graves
7.7%inclusion3 decks39 decks
7%synergy
Massacre Girl
7.7%inclusion3 decks39 decks
0%synergy
Palladium Myr
7.7%inclusion3 decks39 decks
6%synergy
Massacre Wurm
7.7%inclusion3 decks39 decks
-10%synergy
Phyrexian Digester
7.7%inclusion3 decks39 decks
8%synergy
Suspicious Bookcase
7.7%inclusion3 decks39 decks
7%synergy
Scheming Aspirant
7.7%inclusion3 decks39 decks
7%synergy
Unstoppable Slasher
6.1%inclusion2 decks33 decks
0%synergy
Zenos yae Galvus
5.6%inclusion1 decks18 decks
2%synergy
Ahriman
5.6%inclusion1 decks18 decks
5%synergy
Emperor of Bones
5.6%inclusion2 decks36 decks
4%synergy
Murderous Rider
5.1%inclusion2 decks39 decks
-2%synergy
Instants
Defile
54%inclusion21 decks39 decks
16%synergy
Howl from Beyond
51%inclusion20 decks39 decks
51%synergy
Grim Affliction
44%inclusion17 decks39 decks
41%synergy
Tainted Strike
44%inclusion17 decks39 decks
40%synergy
Whisper of the Dross
41%inclusion16 decks39 decks
38%synergy
Go for the Throat
33%inclusion13 decks39 decks
10%synergy
Dismember
33%inclusion13 decks39 decks
22%synergy
Virulent Wound
28%inclusion11 decks39 decks
28%synergy
Withering Torment
27%inclusion9 decks33 decks
-4%synergy
Imp's Mischief
26%inclusion10 decks39 decks
2%synergy
Infernal Grasp
26%inclusion10 decks39 decks
0%synergy
Sugar Rush
23%inclusion9 decks39 decks
23%synergy
Doom Blade
23%inclusion9 decks39 decks
15%synergy
Supernatural Stamina
23%inclusion9 decks39 decks
16%synergy
Malakir Rebirth
21%inclusion8 decks39 decks
-2%synergy
Astarion's Thirst
18%inclusion7 decks39 decks
16%synergy
Force of Despair
18%inclusion7 decks39 decks
10%synergy
Snuff Out
18%inclusion7 decks39 decks
5%synergy
Unlikely Aid
18%inclusion7 decks39 decks
17%synergy
Consuming Corruption
17%inclusion6 decks36 decks
1%synergy
Hero's Downfall
15%inclusion6 decks39 decks
8%synergy
Anoint with Affliction
15%inclusion6 decks39 decks
15%synergy
Undying Malice
15%inclusion6 decks39 decks
6%synergy
Withering Boon
13%inclusion5 decks39 decks
8%synergy
Murder
13%inclusion5 decks39 decks
3%synergy
Sudden Spoiling
13%inclusion5 decks39 decks
3%synergy
Tragic Slip
13%inclusion5 decks39 decks
-8%synergy
Grotesque Mutation
10%inclusion4 decks39 decks
10%synergy
Sheoldred's Edict
10%inclusion4 decks39 decks
-4%synergy
Hatred
10%inclusion4 decks39 decks
9%synergy
Grasp of Darkness
10%inclusion4 decks39 decks
8%synergy
Unnatural Endurance
10%inclusion4 decks39 decks
10%synergy
Baleful Mastery
10%inclusion4 decks39 decks
1%synergy
Professor's Warning
10%inclusion4 decks39 decks
9%synergy
Fell the Profane
8.3%inclusion3 decks36 decks
-10%synergy
Cabal Ritual
7.7%inclusion3 decks39 decks
-10%synergy
Lash of Thorns
7.7%inclusion3 decks39 decks
8%synergy
Armor of Shadows
7.7%inclusion3 decks39 decks
5%synergy
Rush of Vitality
7.7%inclusion3 decks39 decks
7%synergy
Darkness
7.7%inclusion3 decks39 decks
-2%synergy
Offer Immortality
7.7%inclusion3 decks39 decks
6%synergy
Archenemy's Charm
6.7%inclusion1 decks15 decks
-2%synergy
Deadly Rollick
5.1%inclusion2 decks39 decks
-19%synergy
Geth's Verdict
5.1%inclusion2 decks39 decks
5%synergy
Malicious Affliction
5.1%inclusion2 decks39 decks
3%synergy
Heartless Act
5.1%inclusion2 decks39 decks
3%synergy
Boon of Erebos
5.1%inclusion2 decks39 decks
5%synergy
Skeletal Scrying
5.1%inclusion2 decks39 decks
4%synergy
Culling the Weak
5.1%inclusion2 decks39 decks
-10%synergy
Bitter Triumph
5.1%inclusion2 decks39 decks
-5%synergy
Sorceries
Phyresis Outbreak
54%inclusion21 decks39 decks
52%synergy
Sign in Blood
51%inclusion20 decks39 decks
15%synergy
Night's Whisper
41%inclusion16 decks39 decks
17%synergy
Read the Bones
36%inclusion14 decks39 decks
18%synergy
Caress of Phyrexia
36%inclusion14 decks39 decks
35%synergy
Crux of Fate
31%inclusion12 decks39 decks
29%synergy
Vat Emergence
26%inclusion10 decks39 decks
24%synergy
Spread the Sickness
26%inclusion10 decks39 decks
25%synergy
Mutilate
26%inclusion10 decks39 decks
7%synergy
Diabolic Tutor
23%inclusion9 decks39 decks
8%synergy
Toxic Deluge
23%inclusion9 decks39 decks
-14%synergy
Black Sun's Zenith
21%inclusion8 decks39 decks
15%synergy
In Garruk's Wake
18%inclusion7 decks39 decks
14%synergy
Exsanguinate
15%inclusion6 decks39 decks
-9%synergy
Reanimate
15%inclusion6 decks39 decks
-24%synergy
Bubbling Muck
13%inclusion5 decks39 decks
-3%synergy
Feed the Infection
13%inclusion5 decks39 decks
12%synergy
Geth's Summons
13%inclusion5 decks39 decks
12%synergy
Ancient Craving
10%inclusion4 decks39 decks
8%synergy
Ambition's Cost
10%inclusion4 decks39 decks
7%synergy
Damnation
10%inclusion4 decks39 decks
-11%synergy
Blasphemous Edict
10%inclusion3 decks30 decks
-7%synergy
Insatiable Avarice
8.1%inclusion3 decks37 decks
-4%synergy
Extinction Event
7.7%inclusion3 decks39 decks
7%synergy
Profane Tutor
7.7%inclusion3 decks39 decks
3%synergy
Syphon Mind
7.7%inclusion3 decks39 decks
-5%synergy
Nighthaze
7.7%inclusion3 decks39 decks
7%synergy
Languish
7.7%inclusion3 decks39 decks
6%synergy
Dread Return
5.1%inclusion2 decks39 decks
-7%synergy
Agadeem's Awakening
5.1%inclusion2 decks39 decks
-2%synergy
Innocent Blood
5.1%inclusion2 decks39 decks
0%synergy
Praetor's Grasp
5.1%inclusion2 decks39 decks
1%synergy
Gix's Command
5.1%inclusion2 decks39 decks
3%synergy
Decree of Pain
5.1%inclusion2 decks39 decks
-1%synergy
Corrupt
5.1%inclusion2 decks39 decks
2%synergy
Necromantic Selection
5.1%inclusion2 decks39 decks
3%synergy
Beseech the Queen
5.1%inclusion2 decks39 decks
-1%synergy
Grim Tutor
5.1%inclusion2 decks39 decks
-7%synergy
Utility Artifacts
Nightmare Lash
51%inclusion20 decks39 decks
49%synergy
Fireshrieker
51%inclusion20 decks39 decks
49%synergy
Contagion Clasp
46%inclusion18 decks39 decks
44%synergy
Jet Medallion
41%inclusion16 decks39 decks
-20%synergy
Lightning Greaves
36%inclusion14 decks39 decks
2%synergy
Wayfarer's Bauble
33%inclusion13 decks39 decks
17%synergy
Whispersilk Cloak
33%inclusion13 decks39 decks
27%synergy
Contagion Engine
31%inclusion12 decks39 decks
29%synergy
Champion's Helm
31%inclusion12 decks39 decks
29%synergy
Hero's Blade
31%inclusion12 decks39 decks
30%synergy
Trailblazer's Boots
28%inclusion11 decks39 decks
26%synergy
The Darkness Crystal
22%inclusion4 decks18 decks
3%synergy
Nettlecyst
21%inclusion8 decks39 decks
20%synergy
Cranial Plating
21%inclusion8 decks39 decks
17%synergy
Strata Scythe
21%inclusion8 decks39 decks
20%synergy
Leyline Axe
20%inclusion6 decks30 decks
19%synergy
Throne of Geth
18%inclusion7 decks39 decks
18%synergy
Inquisitor's Flail
18%inclusion7 decks39 decks
18%synergy
Loxodon Warhammer
18%inclusion7 decks39 decks
17%synergy
Sword of Vengeance
18%inclusion7 decks39 decks
17%synergy
Commander's Plate
15%inclusion6 decks39 decks
10%synergy
Brotherhood Regalia
14%inclusion5 decks36 decks
11%synergy
Manifold Key
13%inclusion5 decks39 decks
11%synergy
Prowler's Helm
13%inclusion5 decks39 decks
12%synergy
Sword of Truth and Justice
13%inclusion5 decks39 decks
12%synergy
Expedition Map
13%inclusion5 decks39 decks
0%synergy
Sword of the Animist
13%inclusion5 decks39 decks
9%synergy
Genji Glove
11%inclusion2 decks18 decks
10%synergy
Thran Power Suit
10%inclusion4 decks39 decks
10%synergy
Shadowspear
10%inclusion4 decks39 decks
7%synergy
Bontu's Monument
10%inclusion4 decks39 decks
-18%synergy
Livewire Lash
10%inclusion4 decks39 decks
10%synergy
Silver Shroud Costume
10%inclusion4 decks39 decks
9%synergy
Darksteel Plate
10%inclusion4 decks39 decks
8%synergy
Pact Weapon
10%inclusion4 decks39 decks
8%synergy
Hammer of Nazahn
10%inclusion4 decks39 decks
10%synergy
Basilisk Collar
10%inclusion4 decks39 decks
8%synergy
Doc Ock's Tentacles
9.1%inclusion1 decks11 decks
9%synergy
Bloodthorn Flail
7.7%inclusion3 decks39 decks
8%synergy
Viridian Claw
7.7%inclusion3 decks39 decks
8%synergy
Pip-Boy 3000
7.7%inclusion3 decks39 decks
7%synergy
Armillary Sphere
7.7%inclusion3 decks39 decks
7%synergy
Sword of the Chosen
7.7%inclusion3 decks39 decks
8%synergy
Whip of Erebos
7.7%inclusion3 decks39 decks
-3%synergy
O-Naginata
7.7%inclusion3 decks39 decks
7%synergy
Vorpal Sword
7.7%inclusion3 decks39 decks
4%synergy
Adaptive Omnitool
7.7%inclusion2 decks26 decks
7%synergy
Heirloom Blade
7.7%inclusion3 decks39 decks
7%synergy
Prosthetic Injector
7.7%inclusion3 decks39 decks
7%synergy
Ring of Xathrid
7.7%inclusion3 decks39 decks
7%synergy
Enchantments
Phyrexian Arena
49%inclusion19 decks39 decks
8%synergy
Necrogen Communion
41%inclusion16 decks39 decks
39%synergy
Kaya's Ghostform
33%inclusion13 decks39 decks
23%synergy
Unspeakable Symbol
28%inclusion11 decks39 decks
27%synergy
Bad Moon
23%inclusion9 decks39 decks
20%synergy
Fungal Fortitude
21%inclusion8 decks39 decks
19%synergy
Relic Putrescence
15%inclusion6 decks39 decks
15%synergy
Phyresis
15%inclusion6 decks39 decks
13%synergy
Greed
10%inclusion4 decks39 decks
3%synergy
Dauthi Embrace
10%inclusion4 decks39 decks
8%synergy
Endless Scream
10%inclusion4 decks39 decks
10%synergy
Demonic Embrace
10%inclusion4 decks39 decks
9%synergy
Demonic Vigor
7.7%inclusion3 decks39 decks
7%synergy
Phyrexian Scriptures
7.7%inclusion3 decks39 decks
6%synergy
Black Market
7.7%inclusion3 decks39 decks
-13%synergy
Underworld Connections
7.7%inclusion3 decks39 decks
6%synergy
Glistening Oil
7.7%inclusion3 decks39 decks
7%synergy
Shade's Form
7.7%inclusion3 decks39 decks
7%synergy
Eternal Thirst
7.7%inclusion3 decks39 decks
5%synergy
No Mercy
7.7%inclusion3 decks39 decks
0%synergy
Black Market Connections
7.7%inclusion3 decks39 decks
-16%synergy
Super State
6.7%inclusion1 decks15 decks
6%synergy
Eldrazi Conscription
5.1%inclusion2 decks39 decks
5%synergy
Phyrexian Reclamation
5.1%inclusion2 decks39 decks
-5%synergy
Necrosynthesis
5.1%inclusion2 decks39 decks
4%synergy
Dictate of Erebos
5.1%inclusion2 decks39 decks
-5%synergy
Snake Cult Initiation
5.1%inclusion2 decks39 decks
5%synergy
Oubliette
5.1%inclusion2 decks39 decks
2%synergy
Midnight Covenant
5.1%inclusion2 decks39 decks
5%synergy
Planeswalkers
Vraska, Betrayal's Sting
31%inclusion12 decks39 decks
28%synergy
Liliana of the Dark Realms
21%inclusion8 decks39 decks
6%synergy
Utility Lands
Rogue's Passage
59%inclusion23 decks39 decks
40%synergy
Karn's Bastion
51%inclusion20 decks39 decks
47%synergy
Cabal Coffers
49%inclusion19 decks39 decks
-6%synergy
Inkmoth Nexus
38%inclusion15 decks39 decks
37%synergy
Bojuka Bog
36%inclusion14 decks39 decks
-11%synergy
Cabal Stronghold
33%inclusion13 decks39 decks
-2%synergy
Cathedral of War
28%inclusion11 decks39 decks
28%synergy
Shizo, Death's Storehouse
26%inclusion10 decks39 decks
15%synergy
War Room
21%inclusion8 decks39 decks
4%synergy
Nykthos, Shrine to Nyx
18%inclusion7 decks39 decks
-12%synergy
Urborg, Tomb of Yawgmoth
18%inclusion7 decks39 decks
-20%synergy
Witch's Cottage
15%inclusion6 decks39 decks
-9%synergy
Command Beacon
15%inclusion6 decks39 decks
7%synergy
Castle Locthwain
15%inclusion6 decks39 decks
-2%synergy
Barren Moor
13%inclusion5 decks39 decks
3%synergy
Phyrexian Tower
10%inclusion4 decks39 decks
-14%synergy
Mortuary Mire
10%inclusion4 decks39 decks
-3%synergy
Buried Ruin
7.7%inclusion3 decks39 decks
2%synergy
The Black Gate
7.7%inclusion3 decks39 decks
4%synergy
The Dross Pits
7.7%inclusion3 decks39 decks
6%synergy
Polluted Mire
7.7%inclusion3 decks39 decks
4%synergy
Temple of the False God
7.7%inclusion3 decks39 decks
0%synergy
Spawning Pool
7.7%inclusion3 decks39 decks
7%synergy
Vault of Whispers
5.1%inclusion2 decks39 decks
0%synergy
Roadside Reliquary
5.1%inclusion2 decks39 decks
5%synergy
Vesuva
5.1%inclusion2 decks39 decks
2%synergy
Crypt of Agadeem
5.1%inclusion2 decks39 decks
-6%synergy
Forge of Heroes
5.1%inclusion2 decks39 decks
5%synergy
Minas Morgul, Dark Fortress
5.1%inclusion2 decks39 decks
2%synergy
Darksteel Citadel
5.1%inclusion2 decks39 decks
4%synergy
Thespian's Stage
5.1%inclusion2 decks39 decks
-1%synergy
Reliquary Tower
5.1%inclusion2 decks39 decks
-26%synergy
Strip Mine
5.1%inclusion2 decks39 decks
2%synergy
Access Tunnel
5.1%inclusion2 decks39 decks
2%synergy
Mana Artifacts
Sol Ring
90%inclusion35 decks39 decks
3%synergy
Arcane Signet
67%inclusion26 decks39 decks
4%synergy
Charcoal Diamond
41%inclusion16 decks39 decks
18%synergy
Glistening Sphere
41%inclusion16 decks39 decks
40%synergy
Heraldic Banner
28%inclusion11 decks39 decks
23%synergy
Mind Stone
26%inclusion10 decks39 decks
-5%synergy
Caged Sun
23%inclusion9 decks39 decks
11%synergy
Staff of Compleation
23%inclusion9 decks39 decks
21%synergy
Fellwar Stone
13%inclusion5 decks39 decks
-2%synergy
Thought Vessel
13%inclusion5 decks39 decks
-14%synergy
Worn Powerstone
13%inclusion5 decks39 decks
8%synergy
Commander's Sphere
10%inclusion4 decks39 decks
1%synergy
Hedron Archive
10%inclusion4 decks39 decks
7%synergy
Throne of Eldraine
10%inclusion4 decks39 decks
0%synergy
The Soul Stone
7.7%inclusion1 decks13 decks
-5%synergy
Gilded Lotus
7.7%inclusion3 decks39 decks
2%synergy
Everflowing Chalice
5.1%inclusion2 decks39 decks
-1%synergy
Thran Dynamo
5.1%inclusion2 decks39 decks
-1%synergy
Star Compass
5.1%inclusion2 decks39 decks
4%synergy
Liquimetal Torque
5.1%inclusion2 decks39 decks
2%synergy
Sonic Screwdriver
5.1%inclusion2 decks39 decks
4%synergy
Sceptre of Eternal Glory
5.1%inclusion2 decks39 decks
-4%synergy
Lands
Swamp
100%inclusion39 decks39 decks
5%synergy
Myriad Landscape
33%inclusion13 decks39 decks
7%synergy
Mirrex
23%inclusion9 decks39 decks
22%synergy
Malakir Rebirth
21%inclusion8 decks39 decks
-2%synergy
Opal Palace
10%inclusion4 decks39 decks
10%synergy
Daily Bugle Building
9.1%inclusion1 decks11 decks
8%synergy
Fell the Profane
8.3%inclusion3 decks36 decks
-10%synergy
The Seedcore
7.7%inclusion3 decks39 decks
8%synergy
Urza's Cave
5.6%inclusion2 decks36 decks
-3%synergy
Agadeem's Awakening
5.1%inclusion2 decks39 decks
-2%synergy
Cavern of Souls
5.1%inclusion2 decks39 decks
-1%synergy
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