Skithiryx, the Blight Dragon (Commander) - Budget Optimized Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #781
2decks
As CommanderAs CardAverage DeckDecks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Nightmare
100%inclusion2 decks2 decks
99%synergy
Hand of the Praetors
100%inclusion2 decks2 decks
99%synergy
Ichor Rats
100%inclusion2 decks2 decks
97%synergy
Phyrexian Juggernaut
50%inclusion1 decks2 decks
50%synergy
Gorex, the Tombshell
50%inclusion1 decks2 decks
49%synergy
Plague Stinger
50%inclusion1 decks2 decks
49%synergy
Nefarox, Overlord of Grixis
50%inclusion1 decks2 decks
50%synergy
Core Prowler
50%inclusion1 decks2 decks
49%synergy
Grief
50%inclusion1 decks2 decks
48%synergy
Lobelia Sackville-Baggins
50%inclusion1 decks2 decks
49%synergy
Xathrid Gorgon
50%inclusion1 decks2 decks
50%synergy
Extractor Demon
50%inclusion1 decks2 decks
50%synergy
Reaper of Sheoldred
50%inclusion1 decks2 decks
49%synergy
Irini Sengir
50%inclusion1 decks2 decks
50%synergy
Plaguecrafter
50%inclusion1 decks2 decks
30%synergy
Plague Myr
50%inclusion1 decks2 decks
49%synergy
Eater of Hope
50%inclusion1 decks2 decks
50%synergy
Dark Hatchling
50%inclusion1 decks2 decks
50%synergy
Bloodletter of Aclazotz
50%inclusion1 decks2 decks
39%synergy
Flensermite
50%inclusion1 decks2 decks
49%synergy
Ihsan's Shade
50%inclusion1 decks2 decks
50%synergy
Tymaret, Chosen from Death
50%inclusion1 decks2 decks
49%synergy
Gravewaker
50%inclusion1 decks2 decks
50%synergy
Bilious Skulldweller
50%inclusion1 decks2 decks
49%synergy
Ichorclaw Myr
50%inclusion1 decks2 decks
49%synergy
Corpse Cur
50%inclusion1 decks2 decks
50%synergy
Ravenous Necrotitan
50%inclusion1 decks2 decks
50%synergy
Phyrexian Crusader
50%inclusion1 decks2 decks
49%synergy
Gix, Yawgmoth Praetor
50%inclusion1 decks2 decks
45%synergy
Archfiend of Despair
50%inclusion1 decks2 decks
47%synergy
Crypt Ghast
50%inclusion1 decks2 decks
2%synergy
Noxious Gearhulk
50%inclusion1 decks2 decks
43%synergy
Blightbelly Rat
50%inclusion1 decks2 decks
46%synergy
Death-Rattle Oni
50%inclusion1 decks2 decks
50%synergy
Septic Rats
50%inclusion1 decks2 decks
48%synergy
Nimraiser Paladin
50%inclusion1 decks2 decks
50%synergy
Scheming Aspirant
50%inclusion1 decks2 decks
50%synergy
Accursed Marauder
50%inclusion1 decks2 decks
29%synergy
Necropede
50%inclusion1 decks2 decks
50%synergy
Bloodgift Demon
50%inclusion1 decks2 decks
47%synergy
Vrock
50%inclusion1 decks2 decks
50%synergy
Archfiend of Sorrows
50%inclusion1 decks2 decks
50%synergy
Vampire Nighthawk
50%inclusion1 decks2 decks
44%synergy
Instants
Fatal Blow
50%inclusion1 decks2 decks
50%synergy
Sheoldred's Edict
50%inclusion1 decks2 decks
36%synergy
Go for the Throat
50%inclusion1 decks2 decks
27%synergy
Pharika's Libation
50%inclusion1 decks2 decks
49%synergy
Songs of the Damned
50%inclusion1 decks2 decks
45%synergy
Flare of Malice
50%inclusion1 decks2 decks
37%synergy
Dark Ritual
50%inclusion1 decks2 decks
-17%synergy
Sugar Rush
50%inclusion1 decks2 decks
49%synergy
Doom Blade
50%inclusion1 decks2 decks
42%synergy
Slay
50%inclusion1 decks2 decks
50%synergy
Virulent Swipe
50%inclusion1 decks2 decks
50%synergy
Murder
50%inclusion1 decks2 decks
40%synergy
Infernal Grasp
50%inclusion1 decks2 decks
25%synergy
Tainted Strike
50%inclusion1 decks2 decks
47%synergy
Terror
50%inclusion1 decks2 decks
49%synergy
Power Word Kill
50%inclusion1 decks2 decks
49%synergy
Sorceries
Spread the Sickness
50%inclusion1 decks2 decks
49%synergy
Diabolic Tutor
50%inclusion1 decks2 decks
35%synergy
Victimize
50%inclusion1 decks2 decks
24%synergy
Profane Tutor
50%inclusion1 decks2 decks
46%synergy
Duress
50%inclusion1 decks2 decks
43%synergy
Unearth
50%inclusion1 decks2 decks
41%synergy
Crux of Fate
50%inclusion1 decks2 decks
49%synergy
Feed the Swarm
50%inclusion1 decks2 decks
-1%synergy
Read the Bones
50%inclusion1 decks2 decks
32%synergy
Mutilate
50%inclusion1 decks2 decks
32%synergy
Killing Wave
50%inclusion1 decks2 decks
48%synergy
Night's Whisper
50%inclusion1 decks2 decks
26%synergy
Caress of Phyrexia
50%inclusion1 decks2 decks
49%synergy
Dreams of Steel and Oil
50%inclusion1 decks2 decks
50%synergy
Decree of Pain
50%inclusion1 decks2 decks
44%synergy
Lich-Knights' Conquest
50%inclusion1 decks2 decks
48%synergy
Sign in Blood
50%inclusion1 decks2 decks
14%synergy
Diabolic Revelation
50%inclusion1 decks2 decks
50%synergy
Drown in Ichor
50%inclusion1 decks2 decks
46%synergy
Disentomb
50%inclusion1 decks2 decks
49%synergy
Grim Tutor
50%inclusion1 decks2 decks
38%synergy
Utility Artifacts
Winter Moon
100%inclusion2 decks2 decks
98%synergy
Executioner's Hood
50%inclusion1 decks2 decks
50%synergy
Lashwrithe
50%inclusion1 decks2 decks
46%synergy
Tarrian's Soulcleaver
50%inclusion1 decks2 decks
47%synergy
Contagion Clasp
50%inclusion1 decks2 decks
48%synergy
Contagion Engine
50%inclusion1 decks2 decks
48%synergy
Trailblazer's Boots
50%inclusion1 decks2 decks
48%synergy
Whispersilk Cloak
50%inclusion1 decks2 decks
44%synergy
Fireshrieker
50%inclusion1 decks2 decks
48%synergy
Darksteel Plate
50%inclusion1 decks2 decks
48%synergy
Jet Medallion
50%inclusion1 decks2 decks
-11%synergy
Grafted Wargear
50%inclusion1 decks2 decks
50%synergy
Swiftfoot Boots
50%inclusion1 decks2 decks
18%synergy
Loxodon Warhammer
50%inclusion1 decks2 decks
49%synergy
Lich's Mirror
50%inclusion1 decks2 decks
50%synergy
Hero's Heirloom
50%inclusion1 decks2 decks
50%synergy
Enchantments
Necrogen Communion
100%inclusion2 decks2 decks
98%synergy
Thran Vigil
50%inclusion1 decks2 decks
49%synergy
Relic Bane
50%inclusion1 decks2 decks
50%synergy
Contamination
50%inclusion1 decks2 decks
47%synergy
Court of Locthwain
50%inclusion1 decks2 decks
48%synergy
Case of the Stashed Skeleton
50%inclusion1 decks2 decks
48%synergy
Glistening Oil
50%inclusion1 decks2 decks
49%synergy
Grave Pact
50%inclusion1 decks2 decks
31%synergy
Dictate of Erebos
50%inclusion1 decks2 decks
39%synergy
Stab Wound
50%inclusion1 decks2 decks
50%synergy
Fungal Fortitude
50%inclusion1 decks2 decks
49%synergy
Infernal Darkness
50%inclusion1 decks2 decks
49%synergy
Revenge of Ravens
50%inclusion1 decks2 decks
48%synergy
Phyrexian Arena
50%inclusion1 decks2 decks
10%synergy
Leyline of the Void
50%inclusion1 decks2 decks
48%synergy
Virtue of Persistence
50%inclusion1 decks2 decks
45%synergy
Utility Lands
Temple of the False God
50%inclusion1 decks2 decks
42%synergy
Hive of the Eye Tyrant
50%inclusion1 decks2 decks
49%synergy
Mana Artifacts
Unstable Obelisk
50%inclusion1 decks2 decks
49%synergy
Glistening Sphere
50%inclusion1 decks2 decks
49%synergy
Heraldic Banner
50%inclusion1 decks2 decks
44%synergy
Throne of Eldraine
50%inclusion1 decks2 decks
40%synergy
Sol Ring
50%inclusion1 decks2 decks
-36%synergy
Tablet of Compleation
50%inclusion1 decks2 decks
50%synergy
Gilded Lotus
50%inclusion1 decks2 decks
44%synergy
Mox Jasper
50%inclusion1 decks2 decks
50%synergy
Lands
Swamp
100%inclusion2 decks2 decks
5%synergy
Terramorphic Expanse
50%inclusion1 decks2 decks
47%synergy
Myriad Landscape
50%inclusion1 decks2 decks
24%synergy
Evolving Wilds
50%inclusion1 decks2 decks
46%synergy
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