Skithiryx, the Blight Dragon (Commander) - Budget Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
66decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Wickersmith's Tools
10%inclusion1 decks10 decks
10%synergy
Bile-Vial Boggart
10%inclusion1 decks10 decks
9%synergy
Blight Rot
10%inclusion1 decks10 decks
9%synergy
High Synergy Cards
Plague Stinger
88%inclusion58 decks66 decks
87%synergy
Plague Myr
76%inclusion50 decks66 decks
74%synergy
Core Prowler
74%inclusion49 decks66 decks
74%synergy
Infectious Inquiry
76%inclusion50 decks66 decks
73%synergy
Corpse Cur
73%inclusion48 decks66 decks
72%synergy
Reaper of Sheoldred
73%inclusion48 decks66 decks
72%synergy
Vraska's Fall
73%inclusion48 decks66 decks
69%synergy
Ichor Rats
70%inclusion46 decks66 decks
67%synergy
Flensermite
67%inclusion44 decks66 decks
66%synergy
Blightbelly Rat
70%inclusion46 decks66 decks
66%synergy
Top Cards
Drown in Ichor
68%inclusion45 decks66 decks
64%synergy
Whispering Specter
67%inclusion44 decks66 decks
66%synergy
Sign in Blood
64%inclusion42 decks66 decks
28%synergy
Hand of the Praetors
64%inclusion42 decks66 decks
63%synergy
Bilious Skulldweller
62%inclusion41 decks66 decks
61%synergy
Lashwrithe
61%inclusion40 decks66 decks
57%synergy
Howl from Beyond
61%inclusion40 decks66 decks
60%synergy
Fireshrieker
61%inclusion40 decks66 decks
59%synergy
Flesh-Eater Imp
59%inclusion39 decks66 decks
58%synergy
Septic Rats
59%inclusion39 decks66 decks
57%synergy
Creatures
Ichorclaw Myr
56%inclusion37 decks66 decks
56%synergy
Pestilent Syphoner
53%inclusion35 decks66 decks
52%synergy
Necropede
50%inclusion33 decks66 decks
50%synergy
Contagious Nim
48%inclusion32 decks66 decks
48%synergy
Blackcleave Goblin
45%inclusion30 decks66 decks
45%synergy
Gulping Scraptrap
42%inclusion28 decks66 decks
42%synergy
Toxic Nim
39%inclusion26 decks66 decks
39%synergy
Phyrexian Juggernaut
36%inclusion24 decks66 decks
36%synergy
Myr Convert
36%inclusion24 decks66 decks
36%synergy
Leaden Myr
32%inclusion21 decks66 decks
26%synergy
Sheoldred's Headcleaver
30%inclusion20 decks66 decks
30%synergy
Defiler of Flesh
29%inclusion19 decks66 decks
25%synergy
Phyrexian Crusader
29%inclusion19 decks66 decks
28%synergy
Scourge Servant
23%inclusion15 decks66 decks
23%synergy
Nimraiser Paladin
23%inclusion15 decks66 decks
22%synergy
Solemn Simulacrum
21%inclusion14 decks66 decks
-2%synergy
Vector Asp
21%inclusion14 decks66 decks
21%synergy
Gray Merchant of Asphodel
20%inclusion13 decks66 decks
-32%synergy
Phyrexian Digester
18%inclusion12 decks66 decks
18%synergy
Phyrexian Vatmother
18%inclusion12 decks66 decks
18%synergy
Feral Deathgorger
17%inclusion4 decks23 decks
17%synergy
Paragon of Open Graves
17%inclusion11 decks66 decks
16%synergy
Swamp Mosquito
17%inclusion11 decks66 decks
17%synergy
Burnished Hart
17%inclusion11 decks66 decks
9%synergy
Dune Mover
15%inclusion10 decks66 decks
15%synergy
Stinging Hivemaster
14%inclusion9 decks66 decks
13%synergy
Bonepicker Skirge
14%inclusion9 decks66 decks
14%synergy
K'rrik, Son of Yawgmoth
14%inclusion9 decks66 decks
-5%synergy
Crypt Ghast
11%inclusion7 decks66 decks
-38%synergy
Plaguecrafter
9.1%inclusion6 decks66 decks
-11%synergy
Grafted Butcher
9.1%inclusion6 decks66 decks
9%synergy
Pestilent Souleater
9.1%inclusion6 decks66 decks
9%synergy
Scheming Aspirant
9.1%inclusion6 decks66 decks
9%synergy
Scavenger Regent
8.7%inclusion2 decks23 decks
8%synergy
Dread Presence
7.6%inclusion5 decks66 decks
-7%synergy
Gravedigger
7.6%inclusion5 decks66 decks
6%synergy
Chittering Skitterling
7.6%inclusion5 decks66 decks
7%synergy
Massacre Wurm
7.6%inclusion5 decks66 decks
-10%synergy
Kinzu of the Bleak Coven
7.6%inclusion5 decks66 decks
7%synergy
Swarm, Being of Bees
6.3%inclusion1 decks16 decks
6%synergy
Venomized Cat
6.3%inclusion1 decks16 decks
6%synergy
Common Crook
6.3%inclusion1 decks16 decks
5%synergy
Spider-Slayer, Hatred Honed
6.3%inclusion1 decks16 decks
6%synergy
Necroskitter
6.1%inclusion4 decks66 decks
3%synergy
Pilgrim's Eye
6.1%inclusion4 decks66 decks
5%synergy
Ravenous Necrotitan
6.1%inclusion4 decks66 decks
6%synergy
Karumonix, the Rat King
6.1%inclusion4 decks66 decks
2%synergy
Suq'Ata Assassin
6.1%inclusion4 decks66 decks
6%synergy
Blood Pet
6.1%inclusion4 decks66 decks
-2%synergy
Virulent Silencer
5.9%inclusion1 decks17 decks
6%synergy
Instants
Grim Affliction
58%inclusion38 decks66 decks
56%synergy
Whisper of the Dross
53%inclusion35 decks66 decks
50%synergy
Dark Ritual
50%inclusion33 decks66 decks
-17%synergy
Go for the Throat
47%inclusion31 decks66 decks
24%synergy
Defile
45%inclusion30 decks66 decks
8%synergy
Sugar Rush
45%inclusion30 decks66 decks
45%synergy
Doom Blade
44%inclusion29 decks66 decks
36%synergy
Supernatural Stamina
41%inclusion27 decks66 decks
33%synergy
Virulent Wound
39%inclusion26 decks66 decks
39%synergy
Consuming Corruption
33%inclusion17 decks52 decks
17%synergy
Infernal Grasp
30%inclusion20 decks66 decks
5%synergy
Tainted Strike
26%inclusion17 decks66 decks
23%synergy
Unlikely Aid
21%inclusion14 decks66 decks
21%synergy
Murder
21%inclusion14 decks66 decks
11%synergy
Anoint with Affliction
18%inclusion12 decks66 decks
18%synergy
Astarion's Thirst
17%inclusion11 decks66 decks
15%synergy
Hero's Downfall
17%inclusion11 decks66 decks
10%synergy
Undying Malice
17%inclusion11 decks66 decks
7%synergy
Withering Torment
17%inclusion7 decks42 decks
-15%synergy
Blood Pact
14%inclusion9 decks66 decks
9%synergy
Unnatural Endurance
12%inclusion8 decks66 decks
12%synergy
Grotesque Mutation
11%inclusion7 decks66 decks
10%synergy
Undying Evil
9.1%inclusion6 decks66 decks
6%synergy
Rush of Vitality
9.1%inclusion6 decks66 decks
8%synergy
Fake Your Own Death
9.1%inclusion6 decks66 decks
2%synergy
Sudden Spoiling
9.1%inclusion6 decks66 decks
0%synergy
Sheoldred's Edict
7.6%inclusion5 decks66 decks
-7%synergy
Not Dead After All
7.6%inclusion5 decks66 decks
-4%synergy
Virulent Swipe
7.6%inclusion5 decks66 decks
7%synergy
Offer Immortality
7.6%inclusion5 decks66 decks
5%synergy
Dismember
7.6%inclusion5 decks66 decks
-3%synergy
Imp's Mischief
6.1%inclusion4 decks66 decks
-18%synergy
Village Rites
6.1%inclusion4 decks66 decks
-19%synergy
Grasp of Darkness
6.1%inclusion4 decks66 decks
4%synergy
Professor's Warning
6.1%inclusion4 decks66 decks
5%synergy
Scorpion's Sting
5.9%inclusion1 decks17 decks
6%synergy
Fell the Profane
5.7%inclusion3 decks53 decks
-13%synergy
Fight On!
5.6%inclusion1 decks18 decks
3%synergy
Vincent's Limit Break
5.6%inclusion1 decks18 decks
3%synergy
Overkill
5.3%inclusion1 decks19 decks
-2%synergy
Sorceries
Caress of Phyrexia
58%inclusion38 decks66 decks
57%synergy
Feed the Swarm
52%inclusion34 decks66 decks
1%synergy
Read the Bones
47%inclusion31 decks66 decks
30%synergy
Vat Emergence
42%inclusion28 decks66 decks
41%synergy
Spread the Sickness
42%inclusion28 decks66 decks
42%synergy
Phyresis Outbreak
30%inclusion20 decks66 decks
28%synergy
Diabolic Tutor
29%inclusion19 decks66 decks
14%synergy
Night's Whisper
27%inclusion18 decks66 decks
3%synergy
Feed the Infection
23%inclusion15 decks66 decks
22%synergy
Mutilate
23%inclusion15 decks66 decks
5%synergy
Crux of Fate
21%inclusion14 decks66 decks
20%synergy
Duress
18%inclusion12 decks66 decks
12%synergy
Ambition's Cost
17%inclusion11 decks66 decks
14%synergy
Ancient Craving
15%inclusion10 decks66 decks
13%synergy
Fell
15%inclusion7 decks47 decks
11%synergy
Strategic Betrayal
13%inclusion3 decks24 decks
12%synergy
Black Sun's Zenith
12%inclusion8 decks66 decks
6%synergy
Bubbling Muck
11%inclusion7 decks66 decks
-5%synergy
Geth's Summons
11%inclusion7 decks66 decks
10%synergy
Languish
11%inclusion7 decks66 decks
9%synergy
In Garruk's Wake
9.1%inclusion6 decks66 decks
5%synergy
Aggressive Negotiations
8.7%inclusion2 decks23 decks
8%synergy
Prison Break
6.3%inclusion1 decks16 decks
6%synergy
Profane Tutor
6.1%inclusion4 decks66 decks
2%synergy
Bloodcurdling Scream
6.1%inclusion4 decks66 decks
6%synergy
Exsanguinate
6.1%inclusion4 decks66 decks
-18%synergy
Decree of Pain
6.1%inclusion4 decks66 decks
1%synergy
Corrupt
6.1%inclusion4 decks66 decks
3%synergy
Syphon Mind
6.1%inclusion4 decks66 decks
-7%synergy
Risky Research
5.9%inclusion1 decks17 decks
5%synergy
Lethal Protection
5.9%inclusion1 decks17 decks
6%synergy
Venom's Hunger
5.9%inclusion1 decks17 decks
6%synergy
Cornered by Black Mages
5.6%inclusion1 decks18 decks
4%synergy
Resentful Revelation
5.6%inclusion1 decks18 decks
3%synergy
Utility Artifacts
Contagion Clasp
53%inclusion35 decks66 decks
51%synergy
Swiftfoot Boots
48%inclusion32 decks66 decks
17%synergy
Blackblade Reforged
47%inclusion31 decks66 decks
44%synergy
Nightmare Lash
44%inclusion29 decks66 decks
42%synergy
Whispersilk Cloak
38%inclusion25 decks66 decks
32%synergy
Hero's Blade
35%inclusion23 decks66 decks
34%synergy
Throne of Geth
26%inclusion17 decks66 decks
25%synergy
Bloodthorn Flail
18%inclusion12 decks66 decks
18%synergy
Wayfarer's Bauble
18%inclusion12 decks66 decks
2%synergy
Trailblazer's Boots
17%inclusion11 decks66 decks
14%synergy
Strata Scythe
17%inclusion11 decks66 decks
16%synergy
Inquisitor's Flail
17%inclusion11 decks66 decks
16%synergy
Leyline Axe
16%inclusion6 decks37 decks
15%synergy
Grafted Wargear
15%inclusion10 decks66 decks
15%synergy
Decimator Web
15%inclusion10 decks66 decks
15%synergy
Cranial Plating
14%inclusion9 decks66 decks
10%synergy
Grafted Exoskeleton
14%inclusion9 decks66 decks
13%synergy
Contagion Engine
12%inclusion8 decks66 decks
10%synergy
Prowler's Helm
12%inclusion8 decks66 decks
11%synergy
Livewire Lash
12%inclusion8 decks66 decks
12%synergy
Loxodon Warhammer
12%inclusion8 decks66 decks
11%synergy
Prosthetic Injector
11%inclusion7 decks66 decks
10%synergy
Jet Medallion
11%inclusion7 decks66 decks
-51%synergy
Bladed Battle-Fan
11%inclusion7 decks66 decks
10%synergy
Lightning Greaves
11%inclusion7 decks66 decks
-23%synergy
Black Mage's Rod
10%inclusion2 decks20 decks
9%synergy
Pact Weapon
9.1%inclusion6 decks66 decks
7%synergy
Champion's Helm
9.1%inclusion6 decks66 decks
7%synergy
O-Naginata
7.6%inclusion5 decks66 decks
7%synergy
Key to the City
7.6%inclusion5 decks66 decks
6%synergy
Doc Ock's Tentacles
6.3%inclusion1 decks16 decks
6%synergy
Hot Dog Cart
6.3%inclusion1 decks16 decks
6%synergy
Brotherhood Regalia
6.1%inclusion3 decks49 decks
4%synergy
Armillary Sphere
6.1%inclusion4 decks66 decks
6%synergy
Vorpal Sword
6.1%inclusion4 decks66 decks
2%synergy
Haunted Cloak
6.1%inclusion4 decks66 decks
5%synergy
Ribskiff
6.1%inclusion4 decks66 decks
6%synergy
Bontu's Monument
6.1%inclusion4 decks66 decks
-22%synergy
Quick-Draw Katana
5.6%inclusion2 decks36 decks
5%synergy
Monk's Fist
5.6%inclusion1 decks18 decks
6%synergy
Enchantments
Necrogen Communion
50%inclusion33 decks66 decks
48%synergy
Relic Putrescence
41%inclusion27 decks66 decks
41%synergy
Fungal Fortitude
36%inclusion24 decks66 decks
35%synergy
Kaya's Ghostform
29%inclusion19 decks66 decks
19%synergy
Phyrexian Arena
26%inclusion17 decks66 decks
-14%synergy
Endless Scream
24%inclusion16 decks66 decks
24%synergy
Bad Moon
23%inclusion15 decks66 decks
19%synergy
Unspeakable Symbol
21%inclusion14 decks66 decks
20%synergy
Phyresis
15%inclusion10 decks66 decks
13%synergy
Snake Cult Initiation
15%inclusion10 decks66 decks
15%synergy
Demonic Vigor
12%inclusion8 decks66 decks
12%synergy
Shade's Form
9.1%inclusion6 decks66 decks
8%synergy
Unholy Strength
7.6%inclusion5 decks66 decks
7%synergy
Underworld Connections
7.6%inclusion5 decks66 decks
6%synergy
Demonic Embrace
7.6%inclusion5 decks66 decks
7%synergy
Alien Symbiosis
6.3%inclusion1 decks16 decks
6%synergy
Corpses of the Lost
6.1%inclusion4 decks66 decks
5%synergy
Midnight Covenant
6.1%inclusion4 decks66 decks
6%synergy
Planeswalkers
Vraska, Betrayal's Sting
11%inclusion7 decks66 decks
8%synergy
Utility Lands
Rogue's Passage
56%inclusion37 decks66 decks
37%synergy
Karn's Bastion
42%inclusion28 decks66 decks
38%synergy
Bojuka Bog
30%inclusion20 decks66 decks
-17%synergy
Mortuary Mire
24%inclusion16 decks66 decks
11%synergy
Barren Moor
21%inclusion14 decks66 decks
11%synergy
Witch's Cottage
20%inclusion13 decks66 decks
-5%synergy
Cathedral of War
15%inclusion10 decks66 decks
15%synergy
Temple of the False God
14%inclusion9 decks66 decks
6%synergy
Polluted Mire
11%inclusion7 decks66 decks
7%synergy
Buried Ruin
7.6%inclusion5 decks66 decks
2%synergy
Inkmoth Nexus
7.6%inclusion5 decks66 decks
7%synergy
The Dross Pits
7.6%inclusion5 decks66 decks
6%synergy
Memorial to Folly
6.1%inclusion4 decks66 decks
3%synergy
Reliquary Tower
6.1%inclusion4 decks66 decks
-25%synergy
Adventurer's Inn
5.0%inclusion1 decks20 decks
4%synergy
Mana Artifacts
Sol Ring
79%inclusion52 decks66 decks
-7%synergy
Arcane Signet
59%inclusion39 decks66 decks
-3%synergy
Charcoal Diamond
55%inclusion36 decks66 decks
32%synergy
Heraldic Banner
45%inclusion30 decks66 decks
40%synergy
Mind Stone
42%inclusion28 decks66 decks
13%synergy
Commander's Sphere
27%inclusion18 decks66 decks
18%synergy
Everflowing Chalice
17%inclusion11 decks66 decks
11%synergy
Thought Vessel
14%inclusion9 decks66 decks
-13%synergy
Worn Powerstone
14%inclusion9 decks66 decks
9%synergy
Phyrexian Atlas
12%inclusion8 decks66 decks
12%synergy
Caged Sun
11%inclusion7 decks66 decks
-1%synergy
Hedron Archive
11%inclusion7 decks66 decks
7%synergy
Fellwar Stone
11%inclusion7 decks66 decks
-4%synergy
Staff of Compleation
6.1%inclusion4 decks66 decks
4%synergy
Thran Dynamo
6.1%inclusion4 decks66 decks
0%synergy
Lands
Swamp
100%inclusion66 decks66 decks
5%synergy
Myriad Landscape
36%inclusion24 decks66 decks
10%synergy
The Seedcore
18%inclusion12 decks66 decks
18%synergy
Opal Palace
18%inclusion12 decks66 decks
17%synergy
Mirrex
9.1%inclusion6 decks66 decks
8%synergy
Terramorphic Expanse
7.6%inclusion5 decks66 decks
5%synergy
Evolving Wilds
7.6%inclusion5 decks66 decks
4%synergy
Fell the Profane
5.7%inclusion3 decks53 decks
-13%synergy
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