Skithiryx, the Blight Dragon (Commander) - Budget Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
69decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Elephant-Rat
10%inclusion1 decks10 decks
10%synergy
High Synergy Cards
Plague Stinger
90%inclusion62 decks69 decks
89%synergy
Core Prowler
78%inclusion54 decks69 decks
78%synergy
Plague Myr
78%inclusion54 decks69 decks
77%synergy
Corpse Cur
75%inclusion52 decks69 decks
75%synergy
Infectious Inquiry
77%inclusion53 decks69 decks
74%synergy
Reaper of Sheoldred
72%inclusion50 decks69 decks
72%synergy
Whispering Specter
71%inclusion49 decks69 decks
70%synergy
Blightbelly Rat
72%inclusion50 decks69 decks
69%synergy
Ichor Rats
71%inclusion49 decks69 decks
68%synergy
Flensermite
68%inclusion47 decks69 decks
68%synergy
Top Cards
Vraska's Fall
71%inclusion49 decks69 decks
67%synergy
Drown in Ichor
70%inclusion48 decks69 decks
65%synergy
Ichorclaw Myr
67%inclusion46 decks69 decks
66%synergy
Sign in Blood
67%inclusion46 decks69 decks
30%synergy
Hand of the Praetors
65%inclusion45 decks69 decks
64%synergy
Lashwrithe
64%inclusion44 decks69 decks
60%synergy
Howl from Beyond
64%inclusion44 decks69 decks
63%synergy
Fireshrieker
64%inclusion44 decks69 decks
62%synergy
Flesh-Eater Imp
62%inclusion43 decks69 decks
62%synergy
Grim Affliction
61%inclusion42 decks69 decks
59%synergy
Game Changers
Bolas's Citadel
5.8%inclusion4 decks69 decks
-23%synergy
Creatures
Bilious Skulldweller
61%inclusion42 decks69 decks
60%synergy
Septic Rats
61%inclusion42 decks69 decks
59%synergy
Pestilent Syphoner
54%inclusion37 decks69 decks
53%synergy
Necropede
54%inclusion37 decks69 decks
53%synergy
Blackcleave Goblin
49%inclusion34 decks69 decks
49%synergy
Contagious Nim
46%inclusion32 decks69 decks
46%synergy
Myr Convert
41%inclusion28 decks69 decks
40%synergy
Gulping Scraptrap
41%inclusion28 decks69 decks
40%synergy
Toxic Nim
38%inclusion26 decks69 decks
37%synergy
Phyrexian Juggernaut
35%inclusion24 decks69 decks
35%synergy
Leaden Myr
33%inclusion23 decks69 decks
27%synergy
Defiler of Flesh
30%inclusion21 decks69 decks
26%synergy
Phyrexian Crusader
26%inclusion18 decks69 decks
25%synergy
Sheoldred's Headcleaver
25%inclusion17 decks69 decks
24%synergy
Vector Asp
23%inclusion16 decks69 decks
23%synergy
Gray Merchant of Asphodel
20%inclusion14 decks69 decks
-31%synergy
Solemn Simulacrum
19%inclusion13 decks69 decks
-5%synergy
Scourge Servant
19%inclusion13 decks69 decks
19%synergy
Phyrexian Digester
19%inclusion13 decks69 decks
19%synergy
Nimraiser Paladin
19%inclusion13 decks69 decks
19%synergy
Feral Deathgorger
19%inclusion3 decks16 decks
18%synergy
Phyrexian Vatmother
17%inclusion12 decks69 decks
17%synergy
Paragon of Open Graves
16%inclusion11 decks69 decks
15%synergy
Swamp Mosquito
16%inclusion11 decks69 decks
16%synergy
Burnished Hart
16%inclusion11 decks69 decks
8%synergy
Dune Mover
14%inclusion10 decks69 decks
14%synergy
Crypt Ghast
14%inclusion10 decks69 decks
-34%synergy
Stinging Hivemaster
13%inclusion9 decks69 decks
13%synergy
K'rrik, Son of Yawgmoth
13%inclusion9 decks69 decks
-6%synergy
Grafted Butcher
10%inclusion7 decks69 decks
10%synergy
Bonepicker Skirge
10%inclusion7 decks69 decks
10%synergy
Virulent Silencer
10%inclusion1 decks10 decks
10%synergy
Plaguecrafter
8.7%inclusion6 decks69 decks
-11%synergy
Pestilent Souleater
8.7%inclusion6 decks69 decks
9%synergy
Undercity Dire Rat
7.7%inclusion1 decks13 decks
6%synergy
Dread Presence
7.2%inclusion5 decks69 decks
-8%synergy
Gravedigger
7.2%inclusion5 decks69 decks
6%synergy
Massacre Wurm
7.2%inclusion5 decks69 decks
-10%synergy
Scheming Aspirant
7.2%inclusion5 decks69 decks
7%synergy
Scavenger Regent
6.3%inclusion1 decks16 decks
6%synergy
Rot-Curse Rakshasa
6.3%inclusion1 decks16 decks
4%synergy
Pilgrim's Eye
5.8%inclusion4 decks69 decks
4%synergy
Blade of the Oni
5.8%inclusion4 decks69 decks
5%synergy
Suspicious Bookcase
5.8%inclusion4 decks69 decks
5%synergy
Blood Pet
5.8%inclusion4 decks69 decks
-2%synergy
Kinzu of the Bleak Coven
5.8%inclusion4 decks69 decks
5%synergy
Engine Rat
5.6%inclusion1 decks18 decks
4%synergy
Instants
Whisper of the Dross
55%inclusion38 decks69 decks
52%synergy
Dark Ritual
52%inclusion36 decks69 decks
-14%synergy
Go for the Throat
51%inclusion35 decks69 decks
27%synergy
Defile
46%inclusion32 decks69 decks
9%synergy
Supernatural Stamina
45%inclusion31 decks69 decks
38%synergy
Doom Blade
43%inclusion30 decks69 decks
36%synergy
Sugar Rush
41%inclusion28 decks69 decks
40%synergy
Virulent Wound
39%inclusion27 decks69 decks
39%synergy
Infernal Grasp
32%inclusion22 decks69 decks
7%synergy
Consuming Corruption
31%inclusion15 decks48 decks
15%synergy
Tainted Strike
23%inclusion16 decks69 decks
20%synergy
Unlikely Aid
22%inclusion15 decks69 decks
21%synergy
Astarion's Thirst
20%inclusion14 decks69 decks
19%synergy
Murder
20%inclusion14 decks69 decks
10%synergy
Hero's Downfall
16%inclusion11 decks69 decks
9%synergy
Undying Malice
16%inclusion11 decks69 decks
6%synergy
Withering Torment
14%inclusion5 decks37 decks
-18%synergy
Rush of Vitality
13%inclusion9 decks69 decks
12%synergy
Grotesque Mutation
12%inclusion8 decks69 decks
11%synergy
Anoint with Affliction
12%inclusion8 decks69 decks
11%synergy
Blood Pact
12%inclusion8 decks69 decks
7%synergy
Undying Evil
10%inclusion7 decks69 decks
7%synergy
Unnatural Endurance
10%inclusion7 decks69 decks
10%synergy
Sudden Spoiling
10%inclusion7 decks69 decks
1%synergy
Fight On!
9.1%inclusion1 decks11 decks
7%synergy
Vincent's Limit Break
9.1%inclusion1 decks11 decks
6%synergy
Not Dead After All
8.7%inclusion6 decks69 decks
-3%synergy
Fake Your Own Death
8.7%inclusion6 decks69 decks
2%synergy
Offer Immortality
8.7%inclusion6 decks69 decks
7%synergy
Overkill
8.3%inclusion1 decks12 decks
1%synergy
Imp's Mischief
7.2%inclusion5 decks69 decks
-17%synergy
Professor's Warning
7.2%inclusion5 decks69 decks
6%synergy
Desperate Measures
6.3%inclusion1 decks16 decks
6%synergy
Fell the Profane
6.1%inclusion3 decks49 decks
-13%synergy
Village Rites
5.8%inclusion4 decks69 decks
-19%synergy
Deadly Dispute
5.8%inclusion4 decks69 decks
-19%synergy
Grasp of Darkness
5.8%inclusion4 decks69 decks
4%synergy
Virulent Swipe
5.8%inclusion4 decks69 decks
6%synergy
Black Sun's Twilight
5.8%inclusion4 decks69 decks
2%synergy
Dismember
5.8%inclusion4 decks69 decks
-5%synergy
Sorceries
Caress of Phyrexia
61%inclusion42 decks69 decks
60%synergy
Feed the Swarm
55%inclusion38 decks69 decks
4%synergy
Read the Bones
45%inclusion31 decks69 decks
27%synergy
Spread the Sickness
43%inclusion30 decks69 decks
43%synergy
Vat Emergence
42%inclusion29 decks69 decks
40%synergy
Phyresis Outbreak
36%inclusion25 decks69 decks
34%synergy
Diabolic Tutor
29%inclusion20 decks69 decks
14%synergy
Night's Whisper
28%inclusion19 decks69 decks
3%synergy
Mutilate
26%inclusion18 decks69 decks
7%synergy
Crux of Fate
23%inclusion16 decks69 decks
22%synergy
Feed the Infection
20%inclusion14 decks69 decks
20%synergy
Ancient Craving
14%inclusion10 decks69 decks
12%synergy
Ambition's Cost
14%inclusion10 decks69 decks
11%synergy
Fell
14%inclusion6 decks43 decks
10%synergy
Aggressive Negotiations
13%inclusion2 decks16 decks
12%synergy
Duress
12%inclusion8 decks69 decks
5%synergy
In Garruk's Wake
12%inclusion8 decks69 decks
7%synergy
Geth's Summons
12%inclusion8 decks69 decks
11%synergy
Languish
12%inclusion8 decks69 decks
10%synergy
Black Sun's Zenith
10%inclusion7 decks69 decks
4%synergy
Bubbling Muck
10%inclusion7 decks69 decks
-5%synergy
Syphon Mind
10%inclusion7 decks69 decks
-3%synergy
Bloodcurdling Scream
7.2%inclusion5 decks69 decks
7%synergy
Strategic Betrayal
5.9%inclusion1 decks17 decks
5%synergy
Exsanguinate
5.8%inclusion4 decks69 decks
-19%synergy
Gix's Command
5.8%inclusion4 decks69 decks
4%synergy
Decree of Pain
5.8%inclusion4 decks69 decks
0%synergy
Reanimate
5.8%inclusion4 decks69 decks
-33%synergy
Corrupt
5.8%inclusion4 decks69 decks
3%synergy
Toxic Deluge
5.8%inclusion4 decks69 decks
-31%synergy
Utility Artifacts
Contagion Clasp
57%inclusion39 decks69 decks
54%synergy
Blackblade Reforged
52%inclusion36 decks69 decks
49%synergy
Swiftfoot Boots
51%inclusion35 decks69 decks
19%synergy
Nightmare Lash
48%inclusion33 decks69 decks
45%synergy
Whispersilk Cloak
41%inclusion28 decks69 decks
35%synergy
Hero's Blade
41%inclusion28 decks69 decks
40%synergy
Leyline Axe
22%inclusion7 decks32 decks
21%synergy
Throne of Geth
22%inclusion15 decks69 decks
21%synergy
Inquisitor's Flail
20%inclusion14 decks69 decks
20%synergy
Bloodthorn Flail
17%inclusion12 decks69 decks
17%synergy
Wayfarer's Bauble
17%inclusion12 decks69 decks
1%synergy
Trailblazer's Boots
17%inclusion12 decks69 decks
15%synergy
Strata Scythe
17%inclusion12 decks69 decks
17%synergy
Lightning Greaves
16%inclusion11 decks69 decks
-18%synergy
Cranial Plating
14%inclusion10 decks69 decks
11%synergy
Livewire Lash
14%inclusion10 decks69 decks
14%synergy
Grafted Wargear
14%inclusion10 decks69 decks
14%synergy
Decimator Web
14%inclusion10 decks69 decks
14%synergy
Contagion Engine
13%inclusion9 decks69 decks
11%synergy
Doc Ock's Tentacles
13%inclusion1 decks8 decks
12%synergy
Prowler's Helm
12%inclusion8 decks69 decks
11%synergy
Pact Weapon
12%inclusion8 decks69 decks
9%synergy
Jet Medallion
12%inclusion8 decks69 decks
-49%synergy
Loxodon Warhammer
12%inclusion8 decks69 decks
10%synergy
Grafted Exoskeleton
12%inclusion8 decks69 decks
10%synergy
O-Naginata
10%inclusion7 decks69 decks
10%synergy
Prosthetic Injector
10%inclusion7 decks69 decks
10%synergy
Bladed Battle-Fan
10%inclusion7 decks69 decks
10%synergy
Haunted Cloak
8.7%inclusion6 decks69 decks
8%synergy
Key to the City
8.7%inclusion6 decks69 decks
7%synergy
Champion's Helm
8.7%inclusion6 decks69 decks
7%synergy
Black Mage's Rod
7.7%inclusion1 decks13 decks
7%synergy
Sword of Vengeance
7.2%inclusion5 decks69 decks
6%synergy
Brotherhood Regalia
6.7%inclusion3 decks45 decks
4%synergy
Quick-Draw Katana
6.5%inclusion2 decks31 decks
6%synergy
Armillary Sphere
5.8%inclusion4 decks69 decks
5%synergy
Darksteel Axe
5.8%inclusion4 decks69 decks
6%synergy
Bonesplitter
5.8%inclusion4 decks69 decks
6%synergy
Vorpal Sword
5.8%inclusion4 decks69 decks
2%synergy
Basilisk Collar
5.8%inclusion4 decks69 decks
3%synergy
Enchantments
Necrogen Communion
55%inclusion38 decks69 decks
53%synergy
Relic Putrescence
42%inclusion29 decks69 decks
42%synergy
Fungal Fortitude
36%inclusion25 decks69 decks
35%synergy
Kaya's Ghostform
33%inclusion23 decks69 decks
23%synergy
Endless Scream
30%inclusion21 decks69 decks
30%synergy
Phyrexian Arena
29%inclusion20 decks69 decks
-11%synergy
Bad Moon
25%inclusion17 decks69 decks
21%synergy
Unspeakable Symbol
22%inclusion15 decks69 decks
21%synergy
Demonic Vigor
17%inclusion12 decks69 decks
17%synergy
Phyresis
14%inclusion10 decks69 decks
12%synergy
Snake Cult Initiation
13%inclusion9 decks69 decks
13%synergy
Shade's Form
12%inclusion8 decks69 decks
11%synergy
Demonic Embrace
12%inclusion8 decks69 decks
11%synergy
Unholy Strength
10%inclusion7 decks69 decks
10%synergy
Midnight Covenant
8.7%inclusion6 decks69 decks
9%synergy
Underworld Connections
7.2%inclusion5 decks69 decks
5%synergy
Eternal Thirst
7.2%inclusion5 decks69 decks
5%synergy
Corroding Dragonstorm
5.9%inclusion1 decks17 decks
6%synergy
Corpses of the Lost
5.8%inclusion4 decks69 decks
5%synergy
Dark Favor
5.8%inclusion4 decks69 decks
6%synergy
Planeswalkers
Vraska, Betrayal's Sting
7.2%inclusion5 decks69 decks
4%synergy
Utility Lands
Rogue's Passage
62%inclusion43 decks69 decks
44%synergy
Karn's Bastion
45%inclusion31 decks69 decks
41%synergy
Bojuka Bog
32%inclusion22 decks69 decks
-15%synergy
Mortuary Mire
20%inclusion14 decks69 decks
7%synergy
Barren Moor
17%inclusion12 decks69 decks
7%synergy
Witch's Cottage
16%inclusion11 decks69 decks
-9%synergy
Cathedral of War
14%inclusion10 decks69 decks
14%synergy
Temple of the False God
14%inclusion10 decks69 decks
7%synergy
Polluted Mire
10%inclusion7 decks69 decks
6%synergy
Adventurer's Inn
7.7%inclusion1 decks13 decks
6%synergy
Buried Ruin
7.2%inclusion5 decks69 decks
2%synergy
Forge of Heroes
7.2%inclusion5 decks69 decks
7%synergy
Memorial to Folly
5.8%inclusion4 decks69 decks
3%synergy
Inkmoth Nexus
5.8%inclusion4 decks69 decks
5%synergy
Spawning Pool
5.8%inclusion4 decks69 decks
5%synergy
Mana Artifacts
Sol Ring
80%inclusion55 decks69 decks
-7%synergy
Arcane Signet
61%inclusion42 decks69 decks
-2%synergy
Charcoal Diamond
57%inclusion39 decks69 decks
33%synergy
Mind Stone
46%inclusion32 decks69 decks
16%synergy
Heraldic Banner
43%inclusion30 decks69 decks
38%synergy
Commander's Sphere
26%inclusion18 decks69 decks
17%synergy
Everflowing Chalice
16%inclusion11 decks69 decks
10%synergy
Thought Vessel
14%inclusion10 decks69 decks
-12%synergy
Worn Powerstone
14%inclusion10 decks69 decks
10%synergy
Caged Sun
12%inclusion8 decks69 decks
-1%synergy
Fellwar Stone
12%inclusion8 decks69 decks
-3%synergy
Hedron Archive
10%inclusion7 decks69 decks
6%synergy
Phyrexian Atlas
8.7%inclusion6 decks69 decks
8%synergy
Glistening Sphere
7.2%inclusion5 decks69 decks
6%synergy
Staff of Compleation
5.8%inclusion4 decks69 decks
4%synergy
Darksteel Ingot
5.8%inclusion4 decks69 decks
5%synergy
Thran Dynamo
5.8%inclusion4 decks69 decks
0%synergy
Lands
Swamp
100%inclusion69 decks69 decks
5%synergy
Myriad Landscape
32%inclusion22 decks69 decks
5%synergy
Opal Palace
17%inclusion12 decks69 decks
17%synergy
The Seedcore
13%inclusion9 decks69 decks
13%synergy
Mirrex
8.7%inclusion6 decks69 decks
8%synergy
Evolving Wilds
8.7%inclusion6 decks69 decks
5%synergy
Terramorphic Expanse
7.2%inclusion5 decks69 decks
5%synergy
Fell the Profane
6.1%inclusion3 decks49 decks
-13%synergy
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