Skithiryx, the Blight Dragon (Commander) - Budget Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #789
75decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Elephant-Rat
13%inclusion1 decks8 decks
12%synergy
High Synergy Cards
Plague Stinger
91%inclusion68 decks75 decks
90%synergy
Core Prowler
79%inclusion59 decks75 decks
78%synergy
Corpse Cur
77%inclusion58 decks75 decks
77%synergy
Plague Myr
77%inclusion58 decks75 decks
76%synergy
Infectious Inquiry
77%inclusion58 decks75 decks
74%synergy
Reaper of Sheoldred
73%inclusion55 decks75 decks
73%synergy
Ichor Rats
75%inclusion56 decks75 decks
71%synergy
Whispering Specter
71%inclusion53 decks75 decks
70%synergy
Vraska's Fall
73%inclusion55 decks75 decks
70%synergy
Blightbelly Rat
73%inclusion55 decks75 decks
70%synergy
Top Cards
Flensermite
69%inclusion52 decks75 decks
69%synergy
Drown in Ichor
69%inclusion52 decks75 decks
65%synergy
Ichorclaw Myr
68%inclusion51 decks75 decks
67%synergy
Lashwrithe
67%inclusion50 decks75 decks
63%synergy
Sign in Blood
67%inclusion50 decks75 decks
30%synergy
Hand of the Praetors
67%inclusion50 decks75 decks
66%synergy
Howl from Beyond
64%inclusion48 decks75 decks
63%synergy
Flesh-Eater Imp
64%inclusion48 decks75 decks
63%synergy
Fireshrieker
63%inclusion47 decks75 decks
61%synergy
Grim Affliction
61%inclusion46 decks75 decks
59%synergy
Game Changers
Bolas's Citadel
5.3%inclusion4 decks75 decks
-24%synergy
Creatures
Bilious Skulldweller
61%inclusion46 decks75 decks
60%synergy
Septic Rats
60%inclusion45 decks75 decks
58%synergy
Necropede
55%inclusion41 decks75 decks
54%synergy
Pestilent Syphoner
53%inclusion40 decks75 decks
53%synergy
Blackcleave Goblin
49%inclusion37 decks75 decks
49%synergy
Contagious Nim
47%inclusion35 decks75 decks
46%synergy
Myr Convert
44%inclusion33 decks75 decks
43%synergy
Gulping Scraptrap
43%inclusion32 decks75 decks
42%synergy
Phyrexian Juggernaut
37%inclusion28 decks75 decks
37%synergy
Toxic Nim
36%inclusion27 decks75 decks
36%synergy
Leaden Myr
35%inclusion26 decks75 decks
28%synergy
Defiler of Flesh
33%inclusion25 decks75 decks
29%synergy
Phyrexian Crusader
28%inclusion21 decks75 decks
27%synergy
Sheoldred's Headcleaver
25%inclusion19 decks75 decks
25%synergy
Vector Asp
23%inclusion17 decks75 decks
23%synergy
Feral Deathgorger
21%inclusion3 decks14 decks
21%synergy
Solemn Simulacrum
21%inclusion16 decks75 decks
-2%synergy
Nimraiser Paladin
20%inclusion15 decks75 decks
20%synergy
Paragon of Open Graves
19%inclusion14 decks75 decks
18%synergy
Gray Merchant of Asphodel
17%inclusion13 decks75 decks
-34%synergy
Scourge Servant
17%inclusion13 decks75 decks
17%synergy
Phyrexian Digester
17%inclusion13 decks75 decks
17%synergy
Swamp Mosquito
16%inclusion12 decks75 decks
16%synergy
Burnished Hart
16%inclusion12 decks75 decks
8%synergy
Phyrexian Vatmother
16%inclusion12 decks75 decks
16%synergy
Dune Mover
13%inclusion10 decks75 decks
13%synergy
Stinging Hivemaster
13%inclusion10 decks75 decks
13%synergy
Crypt Ghast
13%inclusion10 decks75 decks
-35%synergy
Virulent Silencer
13%inclusion1 decks8 decks
12%synergy
K'rrik, Son of Yawgmoth
12%inclusion9 decks75 decks
-7%synergy
Bonepicker Skirge
11%inclusion8 decks75 decks
11%synergy
Grafted Butcher
9.3%inclusion7 decks75 decks
9%synergy
Undercity Dire Rat
9.1%inclusion1 decks11 decks
7%synergy
Murderous Rider
8.0%inclusion6 decks75 decks
1%synergy
Dread Presence
8.0%inclusion6 decks75 decks
-7%synergy
Plaguecrafter
8.0%inclusion6 decks75 decks
-12%synergy
Pestilent Souleater
8.0%inclusion6 decks75 decks
8%synergy
Scavenger Regent
7.1%inclusion1 decks14 decks
6%synergy
Rot-Curse Rakshasa
7.1%inclusion1 decks14 decks
5%synergy
Gravedigger
6.7%inclusion5 decks75 decks
5%synergy
Blade of the Oni
6.7%inclusion5 decks75 decks
6%synergy
Massacre Wurm
6.7%inclusion5 decks75 decks
-11%synergy
Suspicious Bookcase
6.7%inclusion5 decks75 decks
6%synergy
Scheming Aspirant
6.7%inclusion5 decks75 decks
6%synergy
Engine Rat
6.3%inclusion1 decks16 decks
5%synergy
Pilgrim's Eye
5.3%inclusion4 decks75 decks
4%synergy
Chittering Skitterling
5.3%inclusion4 decks75 decks
4%synergy
Fleshless Gladiator
5.3%inclusion4 decks75 decks
5%synergy
Suq'Ata Assassin
5.3%inclusion4 decks75 decks
5%synergy
Kinzu of the Bleak Coven
5.3%inclusion4 decks75 decks
5%synergy
Instants
Whisper of the Dross
57%inclusion43 decks75 decks
54%synergy
Dark Ritual
53%inclusion40 decks75 decks
-13%synergy
Go for the Throat
51%inclusion38 decks75 decks
27%synergy
Supernatural Stamina
49%inclusion37 decks75 decks
42%synergy
Defile
48%inclusion36 decks75 decks
10%synergy
Sugar Rush
45%inclusion34 decks75 decks
45%synergy
Doom Blade
44%inclusion33 decks75 decks
36%synergy
Virulent Wound
40%inclusion30 decks75 decks
40%synergy
Infernal Grasp
32%inclusion24 decks75 decks
7%synergy
Consuming Corruption
30%inclusion14 decks46 decks
14%synergy
Tainted Strike
25%inclusion19 decks75 decks
22%synergy
Murder
23%inclusion17 decks75 decks
12%synergy
Unlikely Aid
21%inclusion16 decks75 decks
21%synergy
Astarion's Thirst
20%inclusion15 decks75 decks
18%synergy
Hero's Downfall
19%inclusion14 decks75 decks
12%synergy
Rush of Vitality
17%inclusion13 decks75 decks
17%synergy
Withering Torment
15%inclusion5 decks34 decks
-17%synergy
Undying Malice
13%inclusion10 decks75 decks
4%synergy
Anoint with Affliction
12%inclusion9 decks75 decks
11%synergy
Fight On!
11%inclusion1 decks9 decks
9%synergy
Grotesque Mutation
11%inclusion8 decks75 decks
10%synergy
Blood Pact
11%inclusion8 decks75 decks
6%synergy
Overkill
10%inclusion1 decks10 decks
2%synergy
Not Dead After All
9.3%inclusion7 decks75 decks
-2%synergy
Undying Evil
9.3%inclusion7 decks75 decks
6%synergy
Unnatural Endurance
9.3%inclusion7 decks75 decks
9%synergy
Fake Your Own Death
9.3%inclusion7 decks75 decks
3%synergy
Offer Immortality
9.3%inclusion7 decks75 decks
7%synergy
Sudden Spoiling
9.3%inclusion7 decks75 decks
0%synergy
Imp's Mischief
8.0%inclusion6 decks75 decks
-16%synergy
Desperate Measures
7.1%inclusion1 decks14 decks
7%synergy
Deadly Dispute
6.7%inclusion5 decks75 decks
-17%synergy
Professor's Warning
6.7%inclusion5 decks75 decks
5%synergy
Fell the Profane
6.4%inclusion3 decks47 decks
-12%synergy
Village Rites
5.3%inclusion4 decks75 decks
-19%synergy
Grasp of Darkness
5.3%inclusion4 decks75 decks
3%synergy
Bitter Triumph
5.3%inclusion4 decks75 decks
-5%synergy
Virulent Swipe
5.3%inclusion4 decks75 decks
5%synergy
Black Sun's Twilight
5.3%inclusion4 decks75 decks
1%synergy
Corrupted Conviction
5.3%inclusion4 decks75 decks
-7%synergy
Tragic Slip
5.3%inclusion4 decks75 decks
-15%synergy
Dismember
5.3%inclusion4 decks75 decks
-6%synergy
Sorceries
Caress of Phyrexia
60%inclusion45 decks75 decks
59%synergy
Feed the Swarm
56%inclusion42 decks75 decks
5%synergy
Vat Emergence
47%inclusion35 decks75 decks
45%synergy
Spread the Sickness
44%inclusion33 decks75 decks
43%synergy
Read the Bones
44%inclusion33 decks75 decks
26%synergy
Phyresis Outbreak
40%inclusion30 decks75 decks
38%synergy
Diabolic Tutor
29%inclusion22 decks75 decks
14%synergy
Mutilate
27%inclusion20 decks75 decks
8%synergy
Night's Whisper
25%inclusion19 decks75 decks
1%synergy
Crux of Fate
23%inclusion17 decks75 decks
21%synergy
Feed the Infection
19%inclusion14 decks75 decks
18%synergy
Ancient Craving
16%inclusion12 decks75 decks
14%synergy
Fell
15%inclusion6 decks40 decks
11%synergy
Aggressive Negotiations
14%inclusion2 decks14 decks
14%synergy
Ambition's Cost
13%inclusion10 decks75 decks
10%synergy
Duress
12%inclusion9 decks75 decks
5%synergy
In Garruk's Wake
12%inclusion9 decks75 decks
8%synergy
Syphon Mind
11%inclusion8 decks75 decks
-2%synergy
Geth's Summons
11%inclusion8 decks75 decks
10%synergy
Bubbling Muck
9.3%inclusion7 decks75 decks
-6%synergy
Languish
9.3%inclusion7 decks75 decks
8%synergy
Strategic Betrayal
6.7%inclusion1 decks15 decks
6%synergy
Black Sun's Zenith
6.7%inclusion5 decks75 decks
1%synergy
Bloodcurdling Scream
6.7%inclusion5 decks75 decks
7%synergy
Exsanguinate
5.3%inclusion4 decks75 decks
-19%synergy
Decree of Pain
5.3%inclusion4 decks75 decks
0%synergy
Corrupt
5.3%inclusion4 decks75 decks
3%synergy
Toxic Deluge
5.3%inclusion4 decks75 decks
-32%synergy
Utility Artifacts
Contagion Clasp
56%inclusion42 decks75 decks
53%synergy
Swiftfoot Boots
56%inclusion42 decks75 decks
24%synergy
Blackblade Reforged
55%inclusion41 decks75 decks
52%synergy
Nightmare Lash
47%inclusion35 decks75 decks
44%synergy
Whispersilk Cloak
40%inclusion30 decks75 decks
34%synergy
Hero's Blade
40%inclusion30 decks75 decks
40%synergy
Leyline Axe
24%inclusion7 decks29 decks
23%synergy
Throne of Geth
21%inclusion16 decks75 decks
21%synergy
Bloodthorn Flail
19%inclusion14 decks75 decks
19%synergy
Inquisitor's Flail
19%inclusion14 decks75 decks
18%synergy
Wayfarer's Bauble
17%inclusion13 decks75 decks
1%synergy
Trailblazer's Boots
17%inclusion13 decks75 decks
15%synergy
Strata Scythe
17%inclusion13 decks75 decks
17%synergy
Doc Ock's Tentacles
17%inclusion1 decks6 decks
16%synergy
Lightning Greaves
16%inclusion12 decks75 decks
-18%synergy
Decimator Web
16%inclusion12 decks75 decks
16%synergy
Cranial Plating
15%inclusion11 decks75 decks
11%synergy
Bladed Battle-Fan
15%inclusion11 decks75 decks
14%synergy
Livewire Lash
13%inclusion10 decks75 decks
13%synergy
Grafted Wargear
13%inclusion10 decks75 decks
13%synergy
Contagion Engine
12%inclusion9 decks75 decks
10%synergy
Prosthetic Injector
12%inclusion9 decks75 decks
12%synergy
Jet Medallion
12%inclusion9 decks75 decks
-48%synergy
O-Naginata
11%inclusion8 decks75 decks
10%synergy
Prowler's Helm
11%inclusion8 decks75 decks
10%synergy
Pact Weapon
11%inclusion8 decks75 decks
8%synergy
Loxodon Warhammer
11%inclusion8 decks75 decks
9%synergy
Key to the City
9.3%inclusion7 decks75 decks
8%synergy
Champion's Helm
9.3%inclusion7 decks75 decks
7%synergy
Sword of Vengeance
9.3%inclusion7 decks75 decks
8%synergy
Black Mage's Rod
9.1%inclusion1 decks11 decks
8%synergy
Bonesplitter
8.0%inclusion6 decks75 decks
8%synergy
Haunted Cloak
8.0%inclusion6 decks75 decks
7%synergy
Grafted Exoskeleton
8.0%inclusion6 decks75 decks
7%synergy
Quick-Draw Katana
7.1%inclusion2 decks28 decks
7%synergy
Brotherhood Regalia
7.0%inclusion3 decks43 decks
5%synergy
Vorpal Sword
6.7%inclusion5 decks75 decks
3%synergy
Armillary Sphere
5.3%inclusion4 decks75 decks
5%synergy
Darksteel Axe
5.3%inclusion4 decks75 decks
5%synergy
Bontu's Monument
5.3%inclusion4 decks75 decks
-22%synergy
Basilisk Collar
5.3%inclusion4 decks75 decks
3%synergy
Enchantments
Necrogen Communion
59%inclusion44 decks75 decks
57%synergy
Relic Putrescence
41%inclusion31 decks75 decks
41%synergy
Fungal Fortitude
39%inclusion29 decks75 decks
37%synergy
Kaya's Ghostform
33%inclusion25 decks75 decks
23%synergy
Phyrexian Arena
32%inclusion24 decks75 decks
-8%synergy
Endless Scream
31%inclusion23 decks75 decks
30%synergy
Bad Moon
24%inclusion18 decks75 decks
21%synergy
Unspeakable Symbol
19%inclusion14 decks75 decks
18%synergy
Phyresis
16%inclusion12 decks75 decks
14%synergy
Demonic Vigor
15%inclusion11 decks75 decks
14%synergy
Snake Cult Initiation
12%inclusion9 decks75 decks
12%synergy
Demonic Embrace
12%inclusion9 decks75 decks
11%synergy
Unholy Strength
9.3%inclusion7 decks75 decks
9%synergy
Shade's Form
9.3%inclusion7 decks75 decks
9%synergy
Corpses of the Lost
9.3%inclusion7 decks75 decks
8%synergy
Underworld Connections
6.7%inclusion5 decks75 decks
4%synergy
Corroding Dragonstorm
6.7%inclusion1 decks15 decks
6%synergy
Greed
5.3%inclusion4 decks75 decks
-2%synergy
Eternal Thirst
5.3%inclusion4 decks75 decks
3%synergy
Dauthi Embrace
5.3%inclusion4 decks75 decks
4%synergy
Midnight Covenant
5.3%inclusion4 decks75 decks
5%synergy
Planeswalkers
Vraska, Betrayal's Sting
8.0%inclusion6 decks75 decks
5%synergy
Ob Nixilis Reignited
5.3%inclusion4 decks75 decks
3%synergy
Utility Lands
Rogue's Passage
65%inclusion49 decks75 decks
47%synergy
Karn's Bastion
47%inclusion35 decks75 decks
42%synergy
Bojuka Bog
33%inclusion25 decks75 decks
-13%synergy
Mortuary Mire
20%inclusion15 decks75 decks
7%synergy
Barren Moor
19%inclusion14 decks75 decks
8%synergy
Witch's Cottage
15%inclusion11 decks75 decks
-10%synergy
Temple of the False God
15%inclusion11 decks75 decks
7%synergy
Cathedral of War
11%inclusion8 decks75 decks
10%synergy
Adventurer's Inn
9.1%inclusion1 decks11 decks
8%synergy
Polluted Mire
8.0%inclusion6 decks75 decks
4%synergy
Reliquary Tower
8.0%inclusion6 decks75 decks
-23%synergy
Buried Ruin
6.7%inclusion5 decks75 decks
1%synergy
Inkmoth Nexus
6.7%inclusion5 decks75 decks
6%synergy
Forge of Heroes
6.7%inclusion5 decks75 decks
6%synergy
Memorial to Folly
5.3%inclusion4 decks75 decks
2%synergy
The Dross Pits
5.3%inclusion4 decks75 decks
4%synergy
Castle Locthwain
5.3%inclusion4 decks75 decks
-12%synergy
Spawning Pool
5.3%inclusion4 decks75 decks
5%synergy
Mana Artifacts
Sol Ring
80%inclusion60 decks75 decks
-6%synergy
Arcane Signet
63%inclusion47 decks75 decks
0%synergy
Charcoal Diamond
53%inclusion40 decks75 decks
30%synergy
Mind Stone
43%inclusion32 decks75 decks
12%synergy
Heraldic Banner
39%inclusion29 decks75 decks
33%synergy
Commander's Sphere
27%inclusion20 decks75 decks
17%synergy
Thought Vessel
16%inclusion12 decks75 decks
-11%synergy
Everflowing Chalice
15%inclusion11 decks75 decks
9%synergy
Worn Powerstone
13%inclusion10 decks75 decks
9%synergy
Caged Sun
12%inclusion9 decks75 decks
0%synergy
Fellwar Stone
12%inclusion9 decks75 decks
-3%synergy
Hedron Archive
9.3%inclusion7 decks75 decks
5%synergy
Phyrexian Atlas
9.3%inclusion7 decks75 decks
9%synergy
Glistening Sphere
8.0%inclusion6 decks75 decks
7%synergy
Staff of Compleation
6.7%inclusion5 decks75 decks
5%synergy
Thran Dynamo
6.7%inclusion5 decks75 decks
1%synergy
Darksteel Ingot
5.3%inclusion4 decks75 decks
5%synergy
Lands
Swamp
100%inclusion75 decks75 decks
5%synergy
Myriad Landscape
32%inclusion24 decks75 decks
5%synergy
Opal Palace
16%inclusion12 decks75 decks
15%synergy
The Seedcore
13%inclusion10 decks75 decks
13%synergy
Mirrex
11%inclusion8 decks75 decks
10%synergy
Evolving Wilds
8.0%inclusion6 decks75 decks
4%synergy
Terramorphic Expanse
6.7%inclusion5 decks75 decks
4%synergy
Fell the Profane
6.4%inclusion3 decks47 decks
-12%synergy
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