Skithiryx, the Blight Dragon (Commander) - Budget Upgraded Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
Mana Artifacts
Lands
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Bender's Waterskin
33%inclusion1 decks3 decks
33%synergy
The Fire Nation Drill
33%inclusion1 decks3 decks
32%synergy
High Synergy Cards
Howl from Beyond
80%inclusion4 decks5 decks
79%synergy
Plague Stinger
80%inclusion4 decks5 decks
79%synergy
Necrogen Communion
80%inclusion4 decks5 decks
78%synergy
Fireshrieker
80%inclusion4 decks5 decks
78%synergy
Infectious Inquiry
80%inclusion4 decks5 decks
77%synergy
Game Changers
Bolas's Citadel
20%inclusion1 decks5 decks
-9%synergy
Tergrid, God of Fright
20%inclusion1 decks5 decks
12%synergy
Creatures
Feral Deathgorger
60%inclusion3 decks5 decks
60%synergy
Plague Myr
60%inclusion3 decks5 decks
59%synergy
Corpse Cur
60%inclusion3 decks5 decks
60%synergy
Toxic Nim
60%inclusion3 decks5 decks
60%synergy
Septic Rats
60%inclusion3 decks5 decks
58%synergy
Phyrexian Juggernaut
40%inclusion2 decks5 decks
40%synergy
Core Prowler
40%inclusion2 decks5 decks
39%synergy
Blackcleave Goblin
40%inclusion2 decks5 decks
40%synergy
Vector Asp
40%inclusion2 decks5 decks
40%synergy
Reaper of Sheoldred
40%inclusion2 decks5 decks
39%synergy
Flensermite
40%inclusion2 decks5 decks
39%synergy
Massacre Girl
40%inclusion2 decks5 decks
32%synergy
Myr Convert
40%inclusion2 decks5 decks
39%synergy
Bilious Skulldweller
40%inclusion2 decks5 decks
39%synergy
Ichorclaw Myr
40%inclusion2 decks5 decks
39%synergy
Blightbelly Rat
40%inclusion2 decks5 decks
36%synergy
Flesh-Eater Imp
40%inclusion2 decks5 decks
39%synergy
Gulping Scraptrap
40%inclusion2 decks5 decks
39%synergy
Phyrexian Vatmother
40%inclusion2 decks5 decks
40%synergy
Hand of the Praetors
40%inclusion2 decks5 decks
39%synergy
Ichor Rats
40%inclusion2 decks5 decks
37%synergy
Xu-Ifit, Osteoharmonist
33%inclusion1 decks3 decks
31%synergy
Grendel, Spawn of Knull
33%inclusion1 decks3 decks
33%synergy
Zenos yae Galvus
25%inclusion1 decks4 decks
21%synergy
Contagious Nim
20%inclusion1 decks5 decks
20%synergy
Servant of the Stinger
20%inclusion1 decks5 decks
19%synergy
Rune-Scarred Demon
20%inclusion1 decks5 decks
15%synergy
Caustic Bronco
20%inclusion1 decks5 decks
19%synergy
Dread Presence
20%inclusion1 decks5 decks
5%synergy
Whispering Specter
20%inclusion1 decks5 decks
19%synergy
Fell Stinger
20%inclusion1 decks5 decks
17%synergy
Spitting Dilophosaurus
20%inclusion1 decks5 decks
18%synergy
Lobelia Sackville-Baggins
20%inclusion1 decks5 decks
19%synergy
Pestilent Syphoner
20%inclusion1 decks5 decks
19%synergy
Midnight Scavengers
20%inclusion1 decks5 decks
20%synergy
Grim Servant
20%inclusion1 decks5 decks
15%synergy
Plaguecrafter
20%inclusion1 decks5 decks
0%synergy
Morbid Opportunist
20%inclusion1 decks5 decks
-3%synergy
Dimir House Guard
20%inclusion1 decks5 decks
16%synergy
Defiler of Flesh
20%inclusion1 decks5 decks
16%synergy
Gollum, Scheming Guide
20%inclusion1 decks5 decks
20%synergy
Swamp Mosquito
20%inclusion1 decks5 decks
20%synergy
Vile Entomber
20%inclusion1 decks5 decks
14%synergy
Scourge Servant
20%inclusion1 decks5 decks
20%synergy
Stinging Hivemaster
20%inclusion1 decks5 decks
20%synergy
Grafted Butcher
20%inclusion1 decks5 decks
20%synergy
Scavenger Regent
20%inclusion1 decks5 decks
19%synergy
Marauding Blight-Priest
20%inclusion1 decks5 decks
13%synergy
Graf Rats
20%inclusion1 decks5 decks
20%synergy
Burnished Hart
20%inclusion1 decks5 decks
12%synergy
Instants
Vraska's Fall
60%inclusion3 decks5 decks
56%synergy
Infernal Grasp
60%inclusion3 decks5 decks
35%synergy
Grotesque Mutation
40%inclusion2 decks5 decks
40%synergy
Whisper of the Dross
40%inclusion2 decks5 decks
37%synergy
Consuming Corruption
40%inclusion2 decks5 decks
24%synergy
Grim Affliction
40%inclusion2 decks5 decks
38%synergy
Dark Ritual
40%inclusion2 decks5 decks
-27%synergy
Doom Blade
40%inclusion2 decks5 decks
32%synergy
Murder
40%inclusion2 decks5 decks
30%synergy
Fake Your Own Death
40%inclusion2 decks5 decks
33%synergy
Black Sun's Twilight
40%inclusion2 decks5 decks
36%synergy
Withering Torment
40%inclusion2 decks5 decks
8%synergy
Overkill
33%inclusion1 decks3 decks
26%synergy
Archenemy's Charm
33%inclusion1 decks3 decks
25%synergy
Astarion's Thirst
20%inclusion1 decks5 decks
19%synergy
Hero's Downfall
20%inclusion1 decks5 decks
13%synergy
Cut Down
20%inclusion1 decks5 decks
16%synergy
Go for the Throat
20%inclusion1 decks5 decks
-3%synergy
Village Rites
20%inclusion1 decks5 decks
-5%synergy
Fanatical Offering
20%inclusion1 decks5 decks
18%synergy
Anoint with Affliction
20%inclusion1 decks5 decks
19%synergy
Defile
20%inclusion1 decks5 decks
-18%synergy
Skeletal Scrying
20%inclusion1 decks5 decks
19%synergy
Sugar Rush
20%inclusion1 decks5 decks
19%synergy
Undercity's Embrace
20%inclusion1 decks5 decks
20%synergy
Unnatural Endurance
20%inclusion1 decks5 decks
20%synergy
Final Flourish
20%inclusion1 decks5 decks
20%synergy
Lash of Thorns
20%inclusion1 decks5 decks
20%synergy
Armor of Shadows
20%inclusion1 decks5 decks
18%synergy
Supernatural Stamina
20%inclusion1 decks5 decks
13%synergy
Virulent Wound
20%inclusion1 decks5 decks
20%synergy
Rush of Vitality
20%inclusion1 decks5 decks
19%synergy
Bitter Triumph
20%inclusion1 decks5 decks
10%synergy
Unlikely Aid
20%inclusion1 decks5 decks
19%synergy
Raise the Draugr
20%inclusion1 decks5 decks
19%synergy
Undying Malice
20%inclusion1 decks5 decks
10%synergy
Death Denied
20%inclusion1 decks5 decks
19%synergy
Tainted Strike
20%inclusion1 decks5 decks
17%synergy
Vampire's Bite
20%inclusion1 decks5 decks
20%synergy
Consumed by Greed
20%inclusion1 decks5 decks
19%synergy
Bladebrand
20%inclusion1 decks5 decks
19%synergy
Feed the Cycle
20%inclusion1 decks5 decks
19%synergy
Caustic Exhale
20%inclusion1 decks5 decks
20%synergy
Blood Pact
20%inclusion1 decks5 decks
16%synergy
Touch of Moonglove
20%inclusion1 decks5 decks
20%synergy
Professor's Warning
20%inclusion1 decks5 decks
19%synergy
Cruel Feeding
20%inclusion1 decks5 decks
20%synergy
Desperate Measures
20%inclusion1 decks5 decks
19%synergy
Sorceries
Caress of Phyrexia
60%inclusion3 decks5 decks
59%synergy
Sign in Blood
60%inclusion3 decks5 decks
24%synergy
Drown in Ichor
60%inclusion3 decks5 decks
56%synergy
Feed the Swarm
40%inclusion2 decks5 decks
-11%synergy
Night's Whisper
40%inclusion2 decks5 decks
16%synergy
Strategic Betrayal
20%inclusion1 decks5 decks
19%synergy
Vat Emergence
20%inclusion1 decks5 decks
18%synergy
Razaketh's Rite
20%inclusion1 decks5 decks
19%synergy
Diabolic Tutor
20%inclusion1 decks5 decks
5%synergy
Profane Tutor
20%inclusion1 decks5 decks
16%synergy
Duress
20%inclusion1 decks5 decks
13%synergy
Phyresis Outbreak
20%inclusion1 decks5 decks
18%synergy
Crux of Fate
20%inclusion1 decks5 decks
19%synergy
Malicious Eclipse
20%inclusion1 decks5 decks
20%synergy
Read the Bones
20%inclusion1 decks5 decks
2%synergy
Mutilate
20%inclusion1 decks5 decks
1%synergy
Painful Lesson
20%inclusion1 decks5 decks
19%synergy
Demonic Counsel
20%inclusion1 decks5 decks
17%synergy
Ancient Craving
20%inclusion1 decks5 decks
18%synergy
Ambition's Cost
20%inclusion1 decks5 decks
17%synergy
Fell
20%inclusion1 decks5 decks
16%synergy
Murderous Compulsion
20%inclusion1 decks5 decks
20%synergy
Decree of Pain
20%inclusion1 decks5 decks
14%synergy
Extract a Confession
20%inclusion1 decks5 decks
19%synergy
Risky Shortcut
20%inclusion1 decks5 decks
18%synergy
Ruthless Negotiation
20%inclusion1 decks5 decks
20%synergy
Corrupt
20%inclusion1 decks5 decks
17%synergy
Liturgy of Blood
20%inclusion1 decks5 decks
20%synergy
Dirge of Dread
20%inclusion1 decks5 decks
20%synergy
Geth's Summons
20%inclusion1 decks5 decks
20%synergy
Aggressive Negotiations
20%inclusion1 decks5 decks
20%synergy
Flaying Tendrils
20%inclusion1 decks5 decks
20%synergy
Pilfer
20%inclusion1 decks5 decks
17%synergy
Stargaze
20%inclusion1 decks5 decks
19%synergy
Thoughtseize
20%inclusion1 decks5 decks
15%synergy
Languish
20%inclusion1 decks5 decks
18%synergy
Utility Artifacts
Hero's Blade
60%inclusion3 decks5 decks
60%synergy
Leyline Axe
40%inclusion2 decks5 decks
39%synergy
Haunted Cloak
40%inclusion2 decks5 decks
39%synergy
Grafted Wargear
40%inclusion2 decks5 decks
40%synergy
Swiftfoot Boots
40%inclusion2 decks5 decks
8%synergy
Doc Ock's Tentacles
33%inclusion1 decks3 decks
33%synergy
Black Mage's Rod
25%inclusion1 decks4 decks
24%synergy
Bloodthorn Flail
20%inclusion1 decks5 decks
20%synergy
Mephitic Draught
20%inclusion1 decks5 decks
19%synergy
Lashwrithe
20%inclusion1 decks5 decks
16%synergy
Gorgon's Head
20%inclusion1 decks5 decks
20%synergy
Tarrian's Soulcleaver
20%inclusion1 decks5 decks
16%synergy
Masterwork of Ingenuity
20%inclusion1 decks5 decks
20%synergy
Vial of Poison
20%inclusion1 decks5 decks
20%synergy
Contagion Clasp
20%inclusion1 decks5 decks
17%synergy
Sentinel Totem
20%inclusion1 decks5 decks
20%synergy
O-Naginata
20%inclusion1 decks5 decks
20%synergy
Brass Knuckles
20%inclusion1 decks5 decks
20%synergy
Blight Sickle
20%inclusion1 decks5 decks
20%synergy
Prowler's Helm
20%inclusion1 decks5 decks
19%synergy
Vorpal Sword
20%inclusion1 decks5 decks
16%synergy
Cranial Plating
20%inclusion1 decks5 decks
16%synergy
Heirloom Blade
20%inclusion1 decks5 decks
20%synergy
Tithing Blade
20%inclusion1 decks5 decks
17%synergy
Gold Pan
20%inclusion1 decks5 decks
20%synergy
Nevinyrral's Disk
20%inclusion1 decks5 decks
19%synergy
Whispersilk Cloak
20%inclusion1 decks5 decks
14%synergy
The Stasis Coffin
20%inclusion1 decks5 decks
20%synergy
Bilbo's Ring
20%inclusion1 decks5 decks
19%synergy
Jet Medallion
20%inclusion1 decks5 decks
-41%synergy
Goldvein Pick
20%inclusion1 decks5 decks
19%synergy
Bladed Battle-Fan
20%inclusion1 decks5 decks
20%synergy
Lightning Greaves
20%inclusion1 decks5 decks
-14%synergy
Sword of Vengeance
20%inclusion1 decks5 decks
19%synergy
Cloak of the Bat
20%inclusion1 decks5 decks
20%synergy
Decimator Web
20%inclusion1 decks5 decks
20%synergy
Grafted Exoskeleton
20%inclusion1 decks5 decks
19%synergy
Hero's Heirloom
20%inclusion1 decks5 decks
20%synergy
Enchantments
Phyrexian Arena
60%inclusion3 decks5 decks
20%synergy
Unholy Strength
20%inclusion1 decks5 decks
20%synergy
Vow of Torment
20%inclusion1 decks5 decks
20%synergy
Contaminated Bond
20%inclusion1 decks5 decks
20%synergy
Case of the Stashed Skeleton
20%inclusion1 decks5 decks
18%synergy
Necrosynthesis
20%inclusion1 decks5 decks
19%synergy
Shade's Form
20%inclusion1 decks5 decks
19%synergy
Sinister Possession
20%inclusion1 decks5 decks
20%synergy
Shadows of the Past
20%inclusion1 decks5 decks
19%synergy
Rune of Mortality
20%inclusion1 decks5 decks
20%synergy
Quag Sickness
20%inclusion1 decks5 decks
20%synergy
Endless Scream
20%inclusion1 decks5 decks
20%synergy
Fungal Fortitude
20%inclusion1 decks5 decks
19%synergy
Sinister Strength
20%inclusion1 decks5 decks
20%synergy
Hissing Miasma
20%inclusion1 decks5 decks
20%synergy
Crippling Blight
20%inclusion1 decks5 decks
20%synergy
Midnight Covenant
20%inclusion1 decks5 decks
20%synergy
Grave Peril
20%inclusion1 decks5 decks
20%synergy
Planeswalkers
Liliana of the Dark Realms
40%inclusion2 decks5 decks
26%synergy
Utility Lands
Karn's Bastion
60%inclusion3 decks5 decks
56%synergy
Rogue's Passage
60%inclusion3 decks5 decks
41%synergy
Witch's Cottage
40%inclusion2 decks5 decks
15%synergy
Eden, Seat of the Sanctum
33%inclusion1 decks3 decks
33%synergy
Bojuka Bog
20%inclusion1 decks5 decks
-27%synergy
Mortuary Mire
20%inclusion1 decks5 decks
7%synergy
Barren Moor
20%inclusion1 decks5 decks
10%synergy
Cathedral of War
20%inclusion1 decks5 decks
20%synergy
Piranha Marsh
20%inclusion1 decks5 decks
19%synergy
Forge of Heroes
20%inclusion1 decks5 decks
20%synergy
Temple of the False God
20%inclusion1 decks5 decks
12%synergy
Sandstorm Verge
20%inclusion1 decks5 decks
20%synergy
Avishkar Raceway
20%inclusion1 decks5 decks
19%synergy
Quicksand
20%inclusion1 decks5 decks
20%synergy
Mana Artifacts
Heraldic Banner
60%inclusion3 decks5 decks
54%synergy
Sol Ring
60%inclusion3 decks5 decks
-26%synergy
Everflowing Chalice
40%inclusion2 decks5 decks
34%synergy
Arcane Signet
40%inclusion2 decks5 decks
-22%synergy
Charcoal Diamond
40%inclusion2 decks5 decks
17%synergy
Phial of Galadriel
20%inclusion1 decks5 decks
20%synergy
Commander's Sphere
20%inclusion1 decks5 decks
11%synergy
Staff of Compleation
20%inclusion1 decks5 decks
18%synergy
Pristine Talisman
20%inclusion1 decks5 decks
18%synergy
Replicating Ring
20%inclusion1 decks5 decks
20%synergy
Hedron Archive
20%inclusion1 decks5 decks
16%synergy
Buried Treasure
20%inclusion1 decks5 decks
20%synergy
Gilded Lotus
20%inclusion1 decks5 decks
14%synergy
Worn Powerstone
20%inclusion1 decks5 decks
16%synergy
Phyrexian Atlas
20%inclusion1 decks5 decks
20%synergy
Mind Stone
20%inclusion1 decks5 decks
-11%synergy
Dragonstorm Globe
20%inclusion1 decks5 decks
20%synergy
Lands
Swamp
100%inclusion5 decks5 decks
5%synergy
The Seedcore
40%inclusion2 decks5 decks
40%synergy
Command Tower
20%inclusion1 decks5 decks
14%synergy
Vivid Marsh
20%inclusion1 decks5 decks
20%synergy
Myriad Landscape
20%inclusion1 decks5 decks
-6%synergy
Warped Landscape
20%inclusion1 decks5 decks
20%synergy
Opal Palace
20%inclusion1 decks5 decks
19%synergy
Path of Ancestry
20%inclusion1 decks5 decks
15%synergy
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