Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
694decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
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Bitterbloom Bearer
3.3%inclusion3 decks90 decks
1%synergy
Bender's Waterskin
2.7%inclusion3 decks113 decks
2%synergy
Swampsnare Trap
1.6%inclusion1 decks63 decks
1%synergy
Koh, the Face Stealer
1.6%inclusion1 decks63 decks
0%synergy
Realm of Koh
1.6%inclusion1 decks63 decks
-2%synergy
High Synergy Cards
Plague Stinger
81%inclusion563 decks694 decks
80%synergy
Plague Myr
78%inclusion544 decks694 decks
77%synergy
Ichor Rats
79%inclusion547 decks694 decks
76%synergy
Hand of the Praetors
76%inclusion529 decks694 decks
75%synergy
Infectious Inquiry
76%inclusion529 decks694 decks
73%synergy
Vraska's Fall
71%inclusion490 decks694 decks
67%synergy
Whispering Specter
67%inclusion468 decks694 decks
67%synergy
Karn's Bastion
69%inclusion478 decks694 decks
65%synergy
Phyrexian Crusader
65%inclusion453 decks694 decks
64%synergy
Drown in Ichor
66%inclusion458 decks694 decks
62%synergy
Top Cards
Dark Ritual
79%inclusion548 decks694 decks
12%synergy
Lashwrithe
64%inclusion445 decks694 decks
60%synergy
Swiftfoot Boots
63%inclusion440 decks694 decks
32%synergy
Jet Medallion
63%inclusion435 decks694 decks
2%synergy
Blightbelly Rat
62%inclusion427 decks694 decks
58%synergy
Phyrexian Arena
61%inclusion426 decks694 decks
21%synergy
Crypt Ghast
61%inclusion423 decks694 decks
13%synergy
Phyresis Outbreak
61%inclusion422 decks694 decks
59%synergy
Sign in Blood
58%inclusion403 decks694 decks
22%synergy
Nightmare Lash
57%inclusion399 decks694 decks
55%synergy
Game Changers
Demonic Tutor
42%inclusion291 decks694 decks
14%synergy
Vampiric Tutor
31%inclusion216 decks694 decks
10%synergy
Necropotence
22%inclusion152 decks694 decks
7%synergy
Ancient Tomb
21%inclusion147 decks694 decks
9%synergy
Bolas's Citadel
16%inclusion113 decks694 decks
-13%synergy
Mana Vault
15%inclusion104 decks694 decks
8%synergy
Opposition Agent
13%inclusion89 decks694 decks
3%synergy
The One Ring
11%inclusion79 decks694 decks
2%synergy
Chrome Mox
10%inclusion72 decks694 decks
4%synergy
Imperial Seal
9.2%inclusion64 decks694 decks
2%synergy
Creatures
Reaper of Sheoldred
54%inclusion373 decks694 decks
53%synergy
Ichorclaw Myr
47%inclusion326 decks694 decks
46%synergy
Flensermite
45%inclusion312 decks694 decks
44%synergy
Core Prowler
44%inclusion306 decks694 decks
43%synergy
Bilious Skulldweller
44%inclusion304 decks694 decks
43%synergy
Corpse Cur
43%inclusion299 decks694 decks
43%synergy
Flesh-Eater Imp
39%inclusion268 decks694 decks
38%synergy
Pestilent Syphoner
38%inclusion264 decks694 decks
37%synergy
Septic Rats
36%inclusion253 decks694 decks
34%synergy
Phyrexian Obliterator
35%inclusion244 decks694 decks
24%synergy
K'rrik, Son of Yawgmoth
31%inclusion215 decks694 decks
12%synergy
Necropede
29%inclusion198 decks694 decks
28%synergy
Myr Convert
27%inclusion188 decks694 decks
26%synergy
Yawgmoth, Thran Physician
24%inclusion169 decks694 decks
14%synergy
Solemn Simulacrum
22%inclusion153 decks694 decks
-1%synergy
Blightsteel Colossus
22%inclusion153 decks694 decks
21%synergy
Gray Merchant of Asphodel
22%inclusion152 decks694 decks
-30%synergy
Contagious Nim
21%inclusion146 decks694 decks
21%synergy
Leaden Myr
20%inclusion138 decks694 decks
14%synergy
Gulping Scraptrap
18%inclusion127 decks694 decks
18%synergy
Blackcleave Goblin
18%inclusion122 decks694 decks
17%synergy
Phyrexian Juggernaut
16%inclusion108 decks694 decks
15%synergy
Magus of the Coffers
15%inclusion103 decks694 decks
8%synergy
Massacre Girl, Known Killer
15%inclusion101 decks694 decks
11%synergy
Defiler of Flesh
14%inclusion98 decks694 decks
10%synergy
Necroskitter
14%inclusion96 decks694 decks
10%synergy
Dauthi Voidwalker
14%inclusion95 decks694 decks
-2%synergy
Sheoldred, Whispering One
13%inclusion92 decks694 decks
1%synergy
Dread Presence
13%inclusion90 decks694 decks
-2%synergy
Phyrexian Vatmother
13%inclusion90 decks694 decks
13%synergy
Toxic Nim
12%inclusion86 decks694 decks
12%synergy
Grafted Butcher
12%inclusion83 decks694 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion80 decks694 decks
11%synergy
Filth
11%inclusion79 decks694 decks
9%synergy
Dark Confidant
11%inclusion77 decks694 decks
4%synergy
Silent Arbiter
10%inclusion68 decks694 decks
8%synergy
Nirkana Revenant
9.4%inclusion65 decks694 decks
-2%synergy
Phyrexian Digester
9.4%inclusion65 decks694 decks
9%synergy
Sheoldred, the Apocalypse
9.1%inclusion63 decks694 decks
-6%synergy
Burnished Hart
8.6%inclusion60 decks694 decks
1%synergy
Maha, Its Feathers Night
8.1%inclusion39 decks481 decks
3%synergy
Nimraiser Paladin
8.1%inclusion56 decks694 decks
8%synergy
Orcish Bowmasters
7.9%inclusion55 decks694 decks
-6%synergy
Vector Asp
7.6%inclusion53 decks694 decks
8%synergy
Gwenom, Remorseless
7.0%inclusion8 decks115 decks
4%synergy
Massacre Wurm
6.9%inclusion48 decks694 decks
-11%synergy
Swamp Mosquito
6.9%inclusion48 decks694 decks
7%synergy
Brass Squire
6.8%inclusion47 decks694 decks
6%synergy
Scourge Servant
6.6%inclusion46 decks694 decks
7%synergy
Paragon of Open Graves
6.1%inclusion42 decks694 decks
5%synergy
Instants
Howl from Beyond
52%inclusion362 decks694 decks
51%synergy
Whisper of the Dross
47%inclusion326 decks694 decks
44%synergy
Defile
45%inclusion309 decks694 decks
7%synergy
Go for the Throat
40%inclusion280 decks694 decks
17%synergy
Tainted Strike
38%inclusion265 decks694 decks
35%synergy
Grim Affliction
36%inclusion252 decks694 decks
34%synergy
Deadly Rollick
33%inclusion227 decks694 decks
9%synergy
Infernal Grasp
32%inclusion223 decks694 decks
7%synergy
Withering Torment
29%inclusion117 decks403 decks
-3%synergy
Dismember
29%inclusion198 decks694 decks
18%synergy
Cabal Ritual
27%inclusion189 decks694 decks
9%synergy
Imp's Mischief
27%inclusion185 decks694 decks
3%synergy
Sugar Rush
24%inclusion169 decks694 decks
24%synergy
Supernatural Stamina
22%inclusion154 decks694 decks
15%synergy
Hatred
20%inclusion139 decks694 decks
19%synergy
Astarion's Thirst
19%inclusion133 decks694 decks
18%synergy
Virulent Wound
18%inclusion128 decks694 decks
18%synergy
Sudden Spoiling
18%inclusion125 decks694 decks
9%synergy
Malakir Rebirth
18%inclusion122 decks694 decks
-5%synergy
Consuming Corruption
18%inclusion93 decks531 decks
1%synergy
Snuff Out
17%inclusion118 decks694 decks
4%synergy
Archenemy's Charm
16%inclusion20 decks125 decks
7%synergy
Hero's Downfall
16%inclusion110 decks694 decks
9%synergy
Doom Blade
15%inclusion104 decks694 decks
7%synergy
Fell the Profane
14%inclusion74 decks537 decks
-5%synergy
Force of Despair
13%inclusion93 decks694 decks
6%synergy
Unlikely Aid
13%inclusion89 decks694 decks
12%synergy
Murder
12%inclusion86 decks694 decks
2%synergy
Anoint with Affliction
12%inclusion85 decks694 decks
12%synergy
Baleful Mastery
12%inclusion80 decks694 decks
2%synergy
Darkness
10%inclusion71 decks694 decks
1%synergy
Withering Boon
10%inclusion70 decks694 decks
6%synergy
Sheoldred's Edict
10%inclusion66 decks694 decks
-5%synergy
Undying Malice
8.6%inclusion60 decks694 decks
-1%synergy
Culling the Weak
8.2%inclusion57 decks694 decks
-7%synergy
Bitter Triumph
7.9%inclusion55 decks694 decks
-2%synergy
Tragic Slip
7.8%inclusion54 decks694 decks
-13%synergy
Rush of Vitality
7.6%inclusion53 decks694 decks
7%synergy
Not Dead After All
7.5%inclusion52 decks694 decks
-4%synergy
Undying Evil
7.5%inclusion52 decks694 decks
4%synergy
Cut Down
7.2%inclusion50 decks694 decks
3%synergy
Soul Shatter
6.6%inclusion46 decks694 decks
-6%synergy
Unnatural Endurance
6.6%inclusion46 decks694 decks
6%synergy
Slaughter Pact
6.2%inclusion43 decks694 decks
3%synergy
Overkill
5.7%inclusion8 decks141 decks
-2%synergy
Blood Pact
5.5%inclusion38 decks694 decks
1%synergy
Sorceries
Feed the Swarm
54%inclusion377 decks694 decks
3%synergy
Night's Whisper
47%inclusion326 decks694 decks
23%synergy
Crux of Fate
41%inclusion284 decks694 decks
40%synergy
Toxic Deluge
40%inclusion279 decks694 decks
3%synergy
Caress of Phyrexia
38%inclusion266 decks694 decks
38%synergy
Read the Bones
34%inclusion233 decks694 decks
16%synergy
Bubbling Muck
30%inclusion209 decks694 decks
14%synergy
Damnation
27%inclusion187 decks694 decks
6%synergy
Vat Emergence
24%inclusion165 decks694 decks
22%synergy
Reanimate
24%inclusion164 decks694 decks
-15%synergy
Diabolic Tutor
23%inclusion157 decks694 decks
8%synergy
Spread the Sickness
18%inclusion128 decks694 decks
18%synergy
Insatiable Avarice
18%inclusion111 decks617 decks
6%synergy
Mutilate
18%inclusion123 decks694 decks
-1%synergy
Grim Tutor
16%inclusion109 decks694 decks
4%synergy
Blasphemous Edict
13%inclusion44 decks327 decks
-4%synergy
Exsanguinate
13%inclusion87 decks694 decks
-12%synergy
Geth's Summons
13%inclusion87 decks694 decks
12%synergy
Black Sun's Zenith
12%inclusion81 decks694 decks
6%synergy
Feed the Infection
9.1%inclusion63 decks694 decks
8%synergy
Profane Tutor
7.5%inclusion52 decks694 decks
3%synergy
In Garruk's Wake
7.3%inclusion51 decks694 decks
3%synergy
Beseech the Queen
7.3%inclusion51 decks694 decks
1%synergy
Syphon Mind
7.2%inclusion50 decks694 decks
-6%synergy
Torment of Hailfire
6.5%inclusion45 decks694 decks
-9%synergy
Fell
6.2%inclusion30 decks481 decks
3%synergy
Praetor's Grasp
5.2%inclusion36 decks694 decks
1%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion362 decks694 decks
49%synergy
Lightning Greaves
52%inclusion359 decks694 decks
18%synergy
Fireshrieker
46%inclusion321 decks694 decks
44%synergy
Contagion Clasp
42%inclusion293 decks694 decks
40%synergy
Whispersilk Cloak
41%inclusion282 decks694 decks
35%synergy
Contagion Engine
37%inclusion257 decks694 decks
35%synergy
Sword of Truth and Justice
37%inclusion255 decks694 decks
36%synergy
Commander's Plate
36%inclusion248 decks694 decks
30%synergy
Shadowspear
28%inclusion194 decks694 decks
24%synergy
The Darkness Crystal
26%inclusion38 decks147 decks
6%synergy
Leyline Axe
22%inclusion73 decks329 decks
21%synergy
Champion's Helm
21%inclusion144 decks694 decks
19%synergy
Hero's Blade
19%inclusion135 decks694 decks
19%synergy
Trailblazer's Boots
19%inclusion133 decks694 decks
17%synergy
Brotherhood Regalia
17%inclusion87 decks503 decks
15%synergy
Sword of the Animist
17%inclusion116 decks694 decks
13%synergy
Mithril Coat
15%inclusion102 decks694 decks
9%synergy
Cranial Plating
15%inclusion102 decks694 decks
11%synergy
Pact Weapon
15%inclusion101 decks694 decks
12%synergy
Throne of Geth
14%inclusion96 decks694 decks
14%synergy
Genji Glove
14%inclusion19 decks140 decks
12%synergy
Sword of Feast and Famine
14%inclusion94 decks694 decks
12%synergy
Expedition Map
13%inclusion90 decks694 decks
1%synergy
Wayfarer's Bauble
13%inclusion90 decks694 decks
-3%synergy
Doc Ock's Tentacles
11%inclusion11 decks101 decks
11%synergy
Strata Scythe
11%inclusion75 decks694 decks
10%synergy
Grafted Exoskeleton
11%inclusion73 decks694 decks
9%synergy
Inquisitor's Flail
10%inclusion71 decks694 decks
10%synergy
Sword of Vengeance
10%inclusion67 decks694 decks
9%synergy
Hammer of Nazahn
8.8%inclusion61 decks694 decks
8%synergy
Loxodon Warhammer
8.8%inclusion61 decks694 decks
7%synergy
Pip-Boy 3000
8.5%inclusion56 decks661 decks
8%synergy
Prowler's Helm
8.4%inclusion58 decks694 decks
7%synergy
Bontu's Monument
8.4%inclusion58 decks694 decks
-20%synergy
Helm of the Host
8.1%inclusion56 decks694 decks
7%synergy
Darksteel Plate
7.9%inclusion55 decks694 decks
6%synergy
Basilisk Collar
7.6%inclusion53 decks694 decks
5%synergy
Grafted Wargear
7.5%inclusion52 decks694 decks
7%synergy
Sensei's Divining Top
7.3%inclusion51 decks694 decks
-1%synergy
Sword of Wealth and Power
7.3%inclusion48 decks662 decks
7%synergy
Vorpal Sword
7.1%inclusion49 decks694 decks
3%synergy
Whip of Erebos
6.5%inclusion45 decks694 decks
-4%synergy
O-Naginata
6.5%inclusion45 decks694 decks
6%synergy
Buster Sword
5.6%inclusion8 decks144 decks
5%synergy
Sword of Fire and Ice
5.5%inclusion38 decks694 decks
5%synergy
Manifold Key
5.3%inclusion37 decks694 decks
4%synergy
Mask of Avacyn
5.2%inclusion36 decks694 decks
4%synergy
Decimator Web
5.2%inclusion36 decks694 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion350 decks694 decks
49%synergy
Unspeakable Symbol
39%inclusion272 decks694 decks
38%synergy
Kaya's Ghostform
30%inclusion209 decks694 decks
20%synergy
Black Market Connections
21%inclusion149 decks694 decks
-2%synergy
Bad Moon
21%inclusion144 decks694 decks
17%synergy
Fungal Fortitude
18%inclusion127 decks694 decks
17%synergy
Phyresis
16%inclusion108 decks694 decks
13%synergy
No Mercy
15%inclusion106 decks694 decks
8%synergy
Relic Putrescence
15%inclusion104 decks694 decks
15%synergy
Endless Scream
15%inclusion102 decks694 decks
14%synergy
Shade's Form
11%inclusion77 decks694 decks
10%synergy
Dauthi Embrace
11%inclusion74 decks694 decks
9%synergy
Snake Cult Initiation
7.9%inclusion55 decks694 decks
8%synergy
Super State
7.9%inclusion10 decks127 decks
8%synergy
Animate Dead
7.2%inclusion50 decks694 decks
-11%synergy
Black Market
7.1%inclusion49 decks694 decks
-14%synergy
Alien Symbiosis
6.9%inclusion7 decks101 decks
7%synergy
Greed
6.2%inclusion43 decks694 decks
-1%synergy
The Meathook Massacre
5.5%inclusion38 decks694 decks
-12%synergy
Glistening Oil
5.5%inclusion38 decks694 decks
5%synergy
Phyrexian Reclamation
5.2%inclusion36 decks694 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion320 decks694 decks
43%synergy
Liliana of the Dark Realms
28%inclusion194 decks694 decks
14%synergy
Utility Lands
Rogue's Passage
67%inclusion466 decks694 decks
49%synergy
Cabal Coffers
62%inclusion428 decks694 decks
7%synergy
Bojuka Bog
48%inclusion334 decks694 decks
1%synergy
Urborg, Tomb of Yawgmoth
47%inclusion328 decks694 decks
10%synergy
Shizo, Death's Storehouse
45%inclusion310 decks694 decks
35%synergy
Inkmoth Nexus
41%inclusion287 decks694 decks
40%synergy
Cabal Stronghold
38%inclusion261 decks694 decks
2%synergy
Nykthos, Shrine to Nyx
25%inclusion176 decks694 decks
-4%synergy
The Black Gate
21%inclusion144 decks694 decks
17%synergy
Cathedral of War
19%inclusion133 decks694 decks
19%synergy
Castle Locthwain
17%inclusion120 decks694 decks
0%synergy
Command Beacon
17%inclusion117 decks694 decks
9%synergy
War Room
16%inclusion109 decks694 decks
-1%synergy
Reliquary Tower
14%inclusion99 decks694 decks
-17%synergy
Witch's Cottage
13%inclusion88 decks694 decks
-12%synergy
Minas Morgul, Dark Fortress
12%inclusion80 decks694 decks
8%synergy
Urza's Saga
11%inclusion78 decks694 decks
3%synergy
Mortuary Mire
10%inclusion70 decks694 decks
-3%synergy
Temple of the False God
9.4%inclusion65 decks694 decks
1%synergy
Lake of the Dead
9.1%inclusion63 decks694 decks
4%synergy
Strip Mine
8.5%inclusion59 decks694 decks
5%synergy
Takenuma, Abandoned Mire
8.4%inclusion58 decks694 decks
-8%synergy
Barren Moor
7.6%inclusion53 decks694 decks
-3%synergy
Maze of Ith
6.6%inclusion46 decks694 decks
3%synergy
Buried Ruin
6.2%inclusion43 decks694 decks
1%synergy
Phyrexian Tower
5.9%inclusion41 decks694 decks
-18%synergy
Thespian's Stage
5.6%inclusion39 decks694 decks
0%synergy
Spymaster's Vault
5.4%inclusion29 decks537 decks
-4%synergy
Homeward Path
5.0%inclusion35 decks694 decks
3%synergy
Mana Artifacts
Sol Ring
90%inclusion628 decks694 decks
4%synergy
Arcane Signet
65%inclusion452 decks694 decks
3%synergy
Glistening Sphere
47%inclusion323 decks694 decks
45%synergy
Mind Stone
33%inclusion230 decks694 decks
3%synergy
Charcoal Diamond
31%inclusion217 decks694 decks
8%synergy
Staff of Compleation
28%inclusion194 decks694 decks
26%synergy
Heraldic Banner
19%inclusion132 decks694 decks
13%synergy
The Soul Stone
18%inclusion21 decks119 decks
5%synergy
Caged Sun
17%inclusion120 decks694 decks
5%synergy
Thought Vessel
16%inclusion108 decks694 decks
-11%synergy
Fellwar Stone
15%inclusion101 decks694 decks
0%synergy
Lotus Petal
13%inclusion88 decks694 decks
5%synergy
Throne of Eldraine
11%inclusion78 decks694 decks
1%synergy
Commander's Sphere
11%inclusion76 decks694 decks
2%synergy
Mox Opal
10%inclusion69 decks694 decks
7%synergy
Everflowing Chalice
10%inclusion68 decks694 decks
4%synergy
Jeweled Lotus
8.9%inclusion62 decks694 decks
7%synergy
Mana Crypt
7.3%inclusion51 decks694 decks
5%synergy
Thran Dynamo
7.3%inclusion51 decks694 decks
1%synergy
Worn Powerstone
6.5%inclusion45 decks694 decks
2%synergy
Sceptre of Eternal Glory
6.5%inclusion45 decks694 decks
-3%synergy
Gilded Lotus
5.9%inclusion41 decks694 decks
0%synergy
Nyx Lotus
5.5%inclusion38 decks694 decks
-1%synergy
Mox Diamond
5.5%inclusion38 decks694 decks
2%synergy
Phyrexian Atlas
5.0%inclusion35 decks694 decks
5%synergy
Lands
Swamp
95%inclusion659 decks694 decks
0%synergy
Myriad Landscape
24%inclusion166 decks694 decks
-3%synergy
Malakir Rebirth
18%inclusion122 decks694 decks
-5%synergy
Cavern of Souls
16%inclusion110 decks694 decks
9%synergy
Mirrex
15%inclusion107 decks694 decks
15%synergy
Fell the Profane
14%inclusion74 decks537 decks
-5%synergy
Opal Palace
8.2%inclusion57 decks694 decks
7%synergy
Urza's Cave
7.6%inclusion43 decks568 decks
-1%synergy
The Seedcore
7.1%inclusion49 decks694 decks
7%synergy
Snow-Covered Swamp
5.9%inclusion41 decks694 decks
-1%synergy
Bloodstained Mire
5.2%inclusion36 decks694 decks
2%synergy
Command Tower
5.2%inclusion36 decks694 decks
0%synergy
Polluted Delta
5.2%inclusion36 decks694 decks
2%synergy
Verdant Catacombs
5.0%inclusion35 decks694 decks
2%synergy
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