Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #795
521decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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The Sackville-Bagginses
13%inclusion1 decks8 decks
12%synergy
Long-Lost Lances
6.3%inclusion1 decks16 decks
6%synergy
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2.3%inclusion1 decks43 decks
2%synergy
Panther Habit
2.3%inclusion1 decks43 decks
2%synergy
Ultron the Annihilator
2.2%inclusion1 decks45 decks
1%synergy
High Synergy Cards
Plague Stinger
77%inclusion402 decks521 decks
76%synergy
Plague Myr
75%inclusion392 decks521 decks
74%synergy
Ichor Rats
75%inclusion389 decks521 decks
72%synergy
Infectious Inquiry
74%inclusion385 decks521 decks
71%synergy
Hand of the Praetors
71%inclusion371 decks521 decks
70%synergy
Vraska's Fall
69%inclusion359 decks521 decks
66%synergy
Karn's Bastion
68%inclusion356 decks521 decks
65%synergy
Whispering Specter
64%inclusion332 decks521 decks
63%synergy
Phyrexian Crusader
63%inclusion328 decks521 decks
62%synergy
Drown in Ichor
65%inclusion339 decks521 decks
61%synergy
Top Cards
Dark Ritual
79%inclusion409 decks521 decks
11%synergy
Jet Medallion
66%inclusion342 decks521 decks
3%synergy
Swiftfoot Boots
62%inclusion321 decks521 decks
30%synergy
Lashwrithe
61%inclusion319 decks521 decks
57%synergy
Phyresis Outbreak
60%inclusion314 decks521 decks
59%synergy
Crypt Ghast
60%inclusion310 decks521 decks
12%synergy
Blightbelly Rat
59%inclusion308 decks521 decks
56%synergy
Phyrexian Arena
58%inclusion302 decks521 decks
19%synergy
Sign in Blood
55%inclusion289 decks521 decks
20%synergy
Feed the Swarm
53%inclusion277 decks521 decks
3%synergy
Game Changers
Demonic Tutor
40%inclusion209 decks521 decks
13%synergy
Vampiric Tutor
30%inclusion155 decks521 decks
9%synergy
Ancient Tomb
20%inclusion102 decks521 decks
8%synergy
Necropotence
19%inclusion99 decks521 decks
5%synergy
Bolas's Citadel
16%inclusion82 decks521 decks
-13%synergy
Mana Vault
14%inclusion71 decks521 decks
7%synergy
Opposition Agent
12%inclusion62 decks521 decks
2%synergy
The One Ring
11%inclusion56 decks521 decks
1%synergy
Chrome Mox
10%inclusion52 decks521 decks
4%synergy
Imperial Seal
8.1%inclusion42 decks521 decks
1%synergy
Creatures
Reaper of Sheoldred
51%inclusion264 decks521 decks
50%synergy
Ichorclaw Myr
44%inclusion231 decks521 decks
44%synergy
Flensermite
44%inclusion229 decks521 decks
43%synergy
Bilious Skulldweller
44%inclusion229 decks521 decks
43%synergy
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40%inclusion207 decks521 decks
39%synergy
Corpse Cur
39%inclusion201 decks521 decks
38%synergy
Pestilent Syphoner
38%inclusion196 decks521 decks
37%synergy
Phyrexian Obliterator
36%inclusion188 decks521 decks
25%synergy
Flesh-Eater Imp
35%inclusion181 decks521 decks
34%synergy
K'rrik, Son of Yawgmoth
34%inclusion176 decks521 decks
14%synergy
Septic Rats
33%inclusion174 decks521 decks
32%synergy
Necropede
27%inclusion142 decks521 decks
27%synergy
Myr Convert
26%inclusion133 decks521 decks
25%synergy
Yawgmoth, Thran Physician
25%inclusion129 decks521 decks
15%synergy
Blightsteel Colossus
23%inclusion119 decks521 decks
22%synergy
Gray Merchant of Asphodel
21%inclusion112 decks521 decks
-29%synergy
Leaden Myr
21%inclusion112 decks521 decks
15%synergy
Solemn Simulacrum
18%inclusion96 decks521 decks
-3%synergy
Contagious Nim
18%inclusion96 decks521 decks
18%synergy
Gulping Scraptrap
18%inclusion95 decks521 decks
18%synergy
Phyrexian Juggernaut
17%inclusion86 decks521 decks
16%synergy
Dauthi Voidwalker
16%inclusion85 decks521 decks
1%synergy
Blackcleave Goblin
16%inclusion84 decks521 decks
16%synergy
Magus of the Coffers
14%inclusion75 decks521 decks
8%synergy
Necroskitter
14%inclusion75 decks521 decks
12%synergy
Toxic Nim
13%inclusion66 decks521 decks
12%synergy
Dread Presence
12%inclusion64 decks521 decks
-1%synergy
Defiler of Flesh
12%inclusion63 decks521 decks
8%synergy
Sheoldred, Whispering One
12%inclusion62 decks521 decks
0%synergy
Phyrexian Vatmother
12%inclusion62 decks521 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion61 decks521 decks
11%synergy
Massacre Girl, Known Killer
11%inclusion59 decks521 decks
8%synergy
Dark Confidant
11%inclusion57 decks521 decks
3%synergy
Filth
11%inclusion56 decks521 decks
8%synergy
Nirkana Revenant
10%inclusion52 decks521 decks
-1%synergy
Silent Arbiter
10%inclusion51 decks521 decks
8%synergy
Maha, Its Feathers Night
9.2%inclusion48 decks521 decks
5%synergy
Sheoldred, the Apocalypse
9.2%inclusion48 decks521 decks
-5%synergy
Grafted Butcher
8.6%inclusion45 decks521 decks
8%synergy
Phyrexian Digester
8.3%inclusion43 decks521 decks
8%synergy
Nimraiser Paladin
8.3%inclusion43 decks521 decks
8%synergy
Vector Asp
8.1%inclusion42 decks521 decks
8%synergy
Brass Squire
7.9%inclusion41 decks521 decks
7%synergy
Swamp Mosquito
7.7%inclusion40 decks521 decks
8%synergy
Burnished Hart
7.7%inclusion40 decks521 decks
1%synergy
Surge Conductor
7.4%inclusion16 decks217 decks
7%synergy
Gwenom, Remorseless
7.1%inclusion15 decks210 decks
3%synergy
Orcish Bowmasters
7.1%inclusion37 decks521 decks
-6%synergy
Massacre Wurm
6.9%inclusion36 decks521 decks
-10%synergy
Scourge Servant
6.1%inclusion32 decks521 decks
6%synergy
Instants
Whisper of the Dross
46%inclusion239 decks521 decks
43%synergy
Howl from Beyond
44%inclusion229 decks521 decks
43%synergy
Defile
44%inclusion227 decks521 decks
8%synergy
Go for the Throat
38%inclusion200 decks521 decks
16%synergy
Tainted Strike
36%inclusion187 decks521 decks
33%synergy
Grim Affliction
35%inclusion184 decks521 decks
34%synergy
Deadly Rollick
32%inclusion168 decks521 decks
7%synergy
Imp's Mischief
31%inclusion161 decks521 decks
6%synergy
Infernal Grasp
31%inclusion161 decks521 decks
6%synergy
Withering Torment
30%inclusion142 decks478 decks
-2%synergy
Cabal Ritual
27%inclusion139 decks521 decks
8%synergy
Dismember
26%inclusion135 decks521 decks
15%synergy
Malakir Rebirth
19%inclusion100 decks521 decks
-4%synergy
Hatred
18%inclusion96 decks521 decks
17%synergy
Astarion's Thirst
18%inclusion94 decks521 decks
17%synergy
Snuff Out
18%inclusion94 decks521 decks
4%synergy
Supernatural Stamina
18%inclusion94 decks521 decks
10%synergy
Archenemy's Charm
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9%synergy
Sudden Spoiling
17%inclusion88 decks521 decks
9%synergy
Consuming Corruption
17%inclusion86 decks521 decks
1%synergy
Virulent Wound
16%inclusion85 decks521 decks
16%synergy
Sugar Rush
15%inclusion80 decks521 decks
15%synergy
Fell the Profane
15%inclusion78 decks521 decks
-5%synergy
Hero's Downfall
14%inclusion74 decks521 decks
8%synergy
Darkness
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3%synergy
Doom Blade
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6%synergy
Anoint with Affliction
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12%synergy
Murder
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3%synergy
Baleful Mastery
12%inclusion62 decks521 decks
4%synergy
Withering Boon
11%inclusion58 decks521 decks
7%synergy
Force of Despair
10%inclusion54 decks521 decks
3%synergy
Unlikely Aid
10%inclusion52 decks521 decks
9%synergy
Sheoldred's Edict
9.0%inclusion47 decks521 decks
-6%synergy
Culling the Weak
9.0%inclusion47 decks521 decks
-9%synergy
Bitter Triumph
8.6%inclusion45 decks521 decks
-1%synergy
Undying Malice
8.6%inclusion45 decks521 decks
-1%synergy
Tragic Slip
7.9%inclusion41 decks521 decks
-11%synergy
Rush of Vitality
7.5%inclusion39 decks521 decks
7%synergy
Cut Down
7.3%inclusion38 decks521 decks
4%synergy
Undying Evil
6.9%inclusion36 decks521 decks
4%synergy
Soul Shatter
6.5%inclusion34 decks521 decks
-5%synergy
Unnatural Endurance
6.0%inclusion31 decks521 decks
6%synergy
Masterful Flourish
5.8%inclusion5 decks86 decks
4%synergy
Not Dead After All
5.4%inclusion28 decks521 decks
-6%synergy
Sorceries
Night's Whisper
48%inclusion248 decks521 decks
23%synergy
Toxic Deluge
40%inclusion209 decks521 decks
3%synergy
Crux of Fate
40%inclusion208 decks521 decks
39%synergy
Caress of Phyrexia
34%inclusion177 decks521 decks
33%synergy
Bubbling Muck
32%inclusion169 decks521 decks
17%synergy
Read the Bones
31%inclusion160 decks521 decks
15%synergy
Reanimate
26%inclusion136 decks521 decks
-14%synergy
Vat Emergence
25%inclusion132 decks521 decks
24%synergy
Damnation
24%inclusion123 decks521 decks
3%synergy
Diabolic Tutor
19%inclusion101 decks521 decks
6%synergy
Mutilate
18%inclusion92 decks521 decks
2%synergy
Spread the Sickness
17%inclusion88 decks521 decks
16%synergy
Insatiable Avarice
17%inclusion88 decks521 decks
6%synergy
Grim Tutor
15%inclusion80 decks521 decks
4%synergy
Exsanguinate
13%inclusion68 decks521 decks
-12%synergy
Black Sun's Zenith
12%inclusion64 decks521 decks
7%synergy
Blasphemous Edict
12%inclusion49 decks406 decks
-4%synergy
Geth's Summons
12%inclusion61 decks521 decks
11%synergy
Feed the Infection
9.4%inclusion49 decks521 decks
9%synergy
In Garruk's Wake
6.7%inclusion35 decks521 decks
3%synergy
Profane Tutor
6.5%inclusion34 decks521 decks
2%synergy
Beseech the Queen
6.5%inclusion34 decks521 decks
1%synergy
Torment of Hailfire
6.3%inclusion33 decks521 decks
-9%synergy
Praetor's Grasp
6.3%inclusion33 decks521 decks
2%synergy
Syphon Mind
6.1%inclusion32 decks521 decks
-6%synergy
Fell
6.0%inclusion31 decks521 decks
3%synergy
Pox Plague
5.8%inclusion5 decks86 decks
0%synergy
Gix's Command
5.2%inclusion27 decks521 decks
3%synergy
Utility Artifacts
Nightmare Lash
52%inclusion271 decks521 decks
50%synergy
Blackblade Reforged
51%inclusion268 decks521 decks
49%synergy
Lightning Greaves
48%inclusion251 decks521 decks
14%synergy
Fireshrieker
44%inclusion230 decks521 decks
42%synergy
Contagion Clasp
43%inclusion223 decks521 decks
41%synergy
Whispersilk Cloak
37%inclusion195 decks521 decks
31%synergy
Commander's Plate
36%inclusion189 decks521 decks
30%synergy
Contagion Engine
36%inclusion187 decks521 decks
34%synergy
Sword of Truth and Justice
34%inclusion177 decks521 decks
33%synergy
Shadowspear
27%inclusion140 decks521 decks
23%synergy
The Darkness Crystal
24%inclusion57 decks235 decks
4%synergy
Champion's Helm
24%inclusion123 decks521 decks
21%synergy
Leyline Axe
21%inclusion85 decks408 decks
20%synergy
Trailblazer's Boots
21%inclusion107 decks521 decks
18%synergy
Hero's Blade
18%inclusion96 decks521 decks
18%synergy
Sword of the Animist
18%inclusion93 decks521 decks
14%synergy
Brotherhood Regalia
17%inclusion86 decks521 decks
14%synergy
Cranial Plating
15%inclusion78 decks521 decks
12%synergy
Expedition Map
15%inclusion77 decks521 decks
3%synergy
Throne of Geth
13%inclusion70 decks521 decks
13%synergy
Pact Weapon
13%inclusion70 decks521 decks
11%synergy
Sword of Feast and Famine
13%inclusion68 decks521 decks
11%synergy
Mithril Coat
13%inclusion67 decks521 decks
7%synergy
Wayfarer's Bauble
12%inclusion64 decks521 decks
-2%synergy
Genji Glove
11%inclusion25 decks228 decks
10%synergy
Grafted Exoskeleton
11%inclusion57 decks521 decks
10%synergy
Inquisitor's Flail
10%inclusion53 decks521 decks
10%synergy
Strata Scythe
10%inclusion52 decks521 decks
9%synergy
Loxodon Warhammer
10%inclusion52 decks521 decks
9%synergy
Basilisk Collar
10%inclusion51 decks521 decks
7%synergy
Hammer of Nazahn
10%inclusion50 decks521 decks
9%synergy
Sword of Vengeance
9.4%inclusion49 decks521 decks
9%synergy
Vorpal Sword
8.6%inclusion45 decks521 decks
5%synergy
Helm of the Host
8.4%inclusion44 decks521 decks
7%synergy
Prowler's Helm
8.1%inclusion42 decks521 decks
7%synergy
Doc Ock's Tentacles
7.5%inclusion15 decks199 decks
7%synergy
Darksteel Plate
7.5%inclusion39 decks521 decks
6%synergy
Bontu's Monument
7.3%inclusion38 decks521 decks
-21%synergy
Sensei's Divining Top
7.1%inclusion37 decks521 decks
-1%synergy
O-Naginata
6.7%inclusion35 decks521 decks
7%synergy
Whip of Erebos
6.5%inclusion34 decks521 decks
-4%synergy
Sword of Wealth and Power
6.5%inclusion34 decks521 decks
6%synergy
Grafted Wargear
6.5%inclusion34 decks521 decks
6%synergy
Sword of Fire and Ice
6.3%inclusion33 decks521 decks
6%synergy
Manifold Key
6.0%inclusion31 decks521 decks
4%synergy
Pip-Boy 3000
5.8%inclusion30 decks521 decks
5%synergy
Buster Sword
5.6%inclusion13 decks232 decks
5%synergy
Silver Shroud Costume
5.6%inclusion29 decks521 decks
4%synergy
Prosthetic Injector
5.2%inclusion27 decks521 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion258 decks521 decks
48%synergy
Unspeakable Symbol
34%inclusion175 decks521 decks
33%synergy
Kaya's Ghostform
30%inclusion156 decks521 decks
20%synergy
Black Market Connections
24%inclusion127 decks521 decks
-0%synergy
Bad Moon
20%inclusion102 decks521 decks
16%synergy
No Mercy
16%inclusion85 decks521 decks
9%synergy
Phyresis
16%inclusion84 decks521 decks
14%synergy
Fungal Fortitude
15%inclusion80 decks521 decks
14%synergy
Relic Putrescence
13%inclusion69 decks521 decks
13%synergy
Endless Scream
12%inclusion64 decks521 decks
12%synergy
Dauthi Embrace
12%inclusion60 decks521 decks
10%synergy
Shade's Form
8.8%inclusion46 decks521 decks
8%synergy
Snake Cult Initiation
8.4%inclusion44 decks521 decks
8%synergy
Animate Dead
8.4%inclusion44 decks521 decks
-9%synergy
Super State
7.8%inclusion17 decks219 decks
7%synergy
Glistening Oil
6.5%inclusion34 decks521 decks
6%synergy
Greed
6.0%inclusion31 decks521 decks
-0%synergy
Black Market
6.0%inclusion31 decks521 decks
-15%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion242 decks521 decks
44%synergy
Liliana of the Dark Realms
33%inclusion174 decks521 decks
20%synergy
Utility Lands
Rogue's Passage
65%inclusion341 decks521 decks
46%synergy
Cabal Coffers
61%inclusion320 decks521 decks
7%synergy
Bojuka Bog
47%inclusion246 decks521 decks
0%synergy
Urborg, Tomb of Yawgmoth
44%inclusion227 decks521 decks
6%synergy
Shizo, Death's Storehouse
42%inclusion219 decks521 decks
32%synergy
Inkmoth Nexus
40%inclusion207 decks521 decks
39%synergy
Cabal Stronghold
35%inclusion183 decks521 decks
1%synergy
Nykthos, Shrine to Nyx
23%inclusion118 decks521 decks
-7%synergy
Cathedral of War
19%inclusion97 decks521 decks
18%synergy
The Black Gate
17%inclusion89 decks521 decks
14%synergy
Castle Locthwain
17%inclusion88 decks521 decks
0%synergy
Reliquary Tower
16%inclusion85 decks521 decks
-13%synergy
Witch's Cottage
14%inclusion73 decks521 decks
-10%synergy
Command Beacon
14%inclusion73 decks521 decks
6%synergy
War Room
14%inclusion71 decks521 decks
-2%synergy
Urza's Saga
12%inclusion61 decks521 decks
4%synergy
Mortuary Mire
10%inclusion52 decks521 decks
-3%synergy
Minas Morgul, Dark Fortress
9.2%inclusion48 decks521 decks
6%synergy
Temple of the False God
9.2%inclusion48 decks521 decks
2%synergy
Takenuma, Abandoned Mire
7.7%inclusion40 decks521 decks
-8%synergy
Lake of the Dead
7.7%inclusion40 decks521 decks
3%synergy
Strip Mine
7.7%inclusion40 decks521 decks
5%synergy
Phyrexian Tower
6.9%inclusion36 decks521 decks
-19%synergy
Barren Moor
6.7%inclusion35 decks521 decks
-3%synergy
Vault of Whispers
6.3%inclusion33 decks521 decks
1%synergy
Maze of Ith
6.0%inclusion31 decks521 decks
3%synergy
Buried Ruin
5.8%inclusion30 decks521 decks
1%synergy
Thespian's Stage
5.8%inclusion30 decks521 decks
1%synergy
Spymaster's Vault
5.6%inclusion29 decks521 decks
-4%synergy
Mana Artifacts
Sol Ring
89%inclusion466 decks521 decks
4%synergy
Arcane Signet
65%inclusion338 decks521 decks
3%synergy
Glistening Sphere
44%inclusion229 decks521 decks
43%synergy
Mind Stone
33%inclusion172 decks521 decks
5%synergy
Charcoal Diamond
31%inclusion164 decks521 decks
10%synergy
Staff of Compleation
29%inclusion149 decks521 decks
27%synergy
Heraldic Banner
18%inclusion95 decks521 decks
13%synergy
Thought Vessel
17%inclusion91 decks521 decks
-7%synergy
Fellwar Stone
17%inclusion86 decks521 decks
2%synergy
Caged Sun
15%inclusion78 decks521 decks
4%synergy
The Soul Stone
15%inclusion31 decks213 decks
-1%synergy
Lotus Petal
14%inclusion72 decks521 decks
6%synergy
Everflowing Chalice
11%inclusion58 decks521 decks
6%synergy
Mox Opal
10%inclusion52 decks521 decks
6%synergy
Throne of Eldraine
10%inclusion50 decks521 decks
0%synergy
Thran Dynamo
10%inclusion50 decks521 decks
4%synergy
Commander's Sphere
9.4%inclusion49 decks521 decks
1%synergy
Gilded Lotus
6.7%inclusion35 decks521 decks
2%synergy
Worn Powerstone
6.3%inclusion33 decks521 decks
2%synergy
Sceptre of Eternal Glory
6.3%inclusion33 decks521 decks
-2%synergy
Mox Amber
6.0%inclusion31 decks521 decks
2%synergy
Extraplanar Lens
5.8%inclusion30 decks521 decks
1%synergy
Lands
Swamp
94%inclusion491 decks521 decks
-1%synergy
Myriad Landscape
24%inclusion124 decks521 decks
-1%synergy
Malakir Rebirth
19%inclusion100 decks521 decks
-4%synergy
Fell the Profane
15%inclusion78 decks521 decks
-5%synergy
Mirrex
15%inclusion77 decks521 decks
14%synergy
Cavern of Souls
15%inclusion76 decks521 decks
8%synergy
Urza's Cave
7.7%inclusion40 decks521 decks
-1%synergy
The Seedcore
7.3%inclusion38 decks521 decks
7%synergy
Snow-Covered Swamp
6.9%inclusion36 decks521 decks
0%synergy
Opal Palace
6.7%inclusion35 decks521 decks
6%synergy
Command Tower
5.4%inclusion28 decks521 decks
-0%synergy
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