Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #794
572decks
As CommanderAs CardAverage DeckDecks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Pox Plague
7.5%inclusion4 decks53 decks
3%synergy
Emeritus of Woe
5.7%inclusion3 decks53 decks
-2%synergy
Grave Researcher
4.7%inclusion3 decks64 decks
-3%synergy
Masterful Flourish
3.8%inclusion2 decks53 decks
3%synergy
Pull from the Grave
3.0%inclusion2 decks66 decks
2%synergy
High Synergy Cards
Plague Stinger
78%inclusion449 decks572 decks
78%synergy
Plague Myr
77%inclusion438 decks572 decks
75%synergy
Ichor Rats
77%inclusion438 decks572 decks
74%synergy
Hand of the Praetors
73%inclusion420 decks572 decks
73%synergy
Infectious Inquiry
75%inclusion429 decks572 decks
72%synergy
Vraska's Fall
69%inclusion397 decks572 decks
66%synergy
Karn's Bastion
69%inclusion396 decks572 decks
65%synergy
Whispering Specter
66%inclusion376 decks572 decks
65%synergy
Phyrexian Crusader
64%inclusion368 decks572 decks
63%synergy
Drown in Ichor
65%inclusion370 decks572 decks
61%synergy
Top Cards
Dark Ritual
77%inclusion438 decks572 decks
10%synergy
Jet Medallion
65%inclusion373 decks572 decks
3%synergy
Swiftfoot Boots
61%inclusion351 decks572 decks
30%synergy
Lashwrithe
61%inclusion349 decks572 decks
57%synergy
Crypt Ghast
61%inclusion347 decks572 decks
13%synergy
Blightbelly Rat
61%inclusion347 decks572 decks
57%synergy
Phyresis Outbreak
60%inclusion346 decks572 decks
59%synergy
Phyrexian Arena
59%inclusion337 decks572 decks
19%synergy
Sign in Blood
55%inclusion314 decks572 decks
20%synergy
Feed the Swarm
53%inclusion305 decks572 decks
3%synergy
Game Changers
Demonic Tutor
41%inclusion233 decks572 decks
13%synergy
Vampiric Tutor
30%inclusion171 decks572 decks
9%synergy
Necropotence
20%inclusion117 decks572 decks
6%synergy
Ancient Tomb
20%inclusion113 decks572 decks
8%synergy
Bolas's Citadel
16%inclusion93 decks572 decks
-12%synergy
Mana Vault
14%inclusion78 decks572 decks
7%synergy
Opposition Agent
11%inclusion65 decks572 decks
2%synergy
The One Ring
10%inclusion57 decks572 decks
1%synergy
Chrome Mox
10%inclusion56 decks572 decks
4%synergy
Imperial Seal
8.4%inclusion48 decks572 decks
1%synergy
Creatures
Reaper of Sheoldred
53%inclusion303 decks572 decks
52%synergy
Ichorclaw Myr
44%inclusion253 decks572 decks
44%synergy
Flensermite
44%inclusion252 decks572 decks
44%synergy
Bilious Skulldweller
42%inclusion242 decks572 decks
41%synergy
Core Prowler
41%inclusion235 decks572 decks
41%synergy
Corpse Cur
40%inclusion226 decks572 decks
39%synergy
Pestilent Syphoner
38%inclusion216 decks572 decks
37%synergy
Phyrexian Obliterator
36%inclusion207 decks572 decks
25%synergy
Flesh-Eater Imp
36%inclusion204 decks572 decks
35%synergy
Septic Rats
34%inclusion196 decks572 decks
32%synergy
K'rrik, Son of Yawgmoth
32%inclusion185 decks572 decks
13%synergy
Necropede
28%inclusion158 decks572 decks
27%synergy
Myr Convert
25%inclusion145 decks572 decks
25%synergy
Yawgmoth, Thran Physician
25%inclusion143 decks572 decks
15%synergy
Blightsteel Colossus
24%inclusion136 decks572 decks
23%synergy
Gray Merchant of Asphodel
23%inclusion129 decks572 decks
-28%synergy
Leaden Myr
21%inclusion122 decks572 decks
15%synergy
Solemn Simulacrum
20%inclusion117 decks572 decks
-1%synergy
Contagious Nim
20%inclusion115 decks572 decks
20%synergy
Gulping Scraptrap
20%inclusion115 decks572 decks
20%synergy
Blackcleave Goblin
17%inclusion98 decks572 decks
17%synergy
Phyrexian Juggernaut
16%inclusion90 decks572 decks
16%synergy
Dauthi Voidwalker
15%inclusion84 decks572 decks
-1%synergy
Necroskitter
15%inclusion83 decks572 decks
12%synergy
Magus of the Coffers
14%inclusion81 decks572 decks
7%synergy
Dread Presence
13%inclusion75 decks572 decks
-1%synergy
Toxic Nim
13%inclusion75 decks572 decks
13%synergy
Defiler of Flesh
13%inclusion74 decks572 decks
9%synergy
Sheoldred, Whispering One
13%inclusion72 decks572 decks
1%synergy
Phyrexian Vatmother
13%inclusion72 decks572 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion71 decks572 decks
12%synergy
Massacre Girl, Known Killer
12%inclusion69 decks572 decks
8%synergy
Dark Confidant
11%inclusion64 decks572 decks
4%synergy
Filth
11%inclusion64 decks572 decks
9%synergy
Silent Arbiter
10%inclusion56 decks572 decks
8%synergy
Grafted Butcher
10%inclusion55 decks572 decks
9%synergy
Nirkana Revenant
8.9%inclusion51 decks572 decks
-2%synergy
Sheoldred, the Apocalypse
8.9%inclusion51 decks572 decks
-6%synergy
Vector Asp
8.7%inclusion50 decks572 decks
9%synergy
Nimraiser Paladin
8.4%inclusion48 decks572 decks
8%synergy
Phyrexian Digester
8.2%inclusion47 decks572 decks
8%synergy
Burnished Hart
8.0%inclusion46 decks572 decks
1%synergy
Maha, Its Feathers Night
7.9%inclusion42 decks531 decks
4%synergy
Brass Squire
7.7%inclusion44 decks572 decks
7%synergy
Swamp Mosquito
7.3%inclusion42 decks572 decks
7%synergy
Massacre Wurm
7.3%inclusion42 decks572 decks
-10%synergy
Gwenom, Remorseless
7.0%inclusion13 decks185 decks
3%synergy
Surge Conductor
6.8%inclusion13 decks192 decks
7%synergy
Scourge Servant
6.6%inclusion38 decks572 decks
7%synergy
Orcish Bowmasters
6.6%inclusion38 decks572 decks
-6%synergy
Instants
Whisper of the Dross
46%inclusion264 decks572 decks
43%synergy
Howl from Beyond
46%inclusion263 decks572 decks
45%synergy
Defile
44%inclusion252 decks572 decks
8%synergy
Go for the Throat
40%inclusion229 decks572 decks
17%synergy
Tainted Strike
37%inclusion210 decks572 decks
34%synergy
Grim Affliction
36%inclusion204 decks572 decks
34%synergy
Deadly Rollick
32%inclusion183 decks572 decks
7%synergy
Infernal Grasp
31%inclusion178 decks572 decks
6%synergy
Withering Torment
30%inclusion136 decks456 decks
-2%synergy
Imp's Mischief
29%inclusion168 decks572 decks
5%synergy
Cabal Ritual
27%inclusion155 decks572 decks
9%synergy
Dismember
26%inclusion150 decks572 decks
16%synergy
Malakir Rebirth
19%inclusion109 decks572 decks
-4%synergy
Supernatural Stamina
19%inclusion106 decks572 decks
11%synergy
Hatred
18%inclusion105 decks572 decks
17%synergy
Sugar Rush
18%inclusion105 decks572 decks
18%synergy
Astarion's Thirst
18%inclusion103 decks572 decks
17%synergy
Consuming Corruption
17%inclusion100 decks572 decks
2%synergy
Snuff Out
17%inclusion100 decks572 decks
4%synergy
Archenemy's Charm
17%inclusion33 decks192 decks
8%synergy
Virulent Wound
17%inclusion97 decks572 decks
17%synergy
Sudden Spoiling
17%inclusion97 decks572 decks
8%synergy
Hero's Downfall
16%inclusion89 decks572 decks
9%synergy
Doom Blade
14%inclusion81 decks572 decks
7%synergy
Fell the Profane
14%inclusion79 decks572 decks
-5%synergy
Anoint with Affliction
13%inclusion74 decks572 decks
12%synergy
Murder
12%inclusion71 decks572 decks
2%synergy
Darkness
12%inclusion71 decks572 decks
2%synergy
Force of Despair
12%inclusion69 decks572 decks
4%synergy
Baleful Mastery
12%inclusion67 decks572 decks
3%synergy
Unlikely Aid
11%inclusion63 decks572 decks
10%synergy
Withering Boon
11%inclusion61 decks572 decks
6%synergy
Sheoldred's Edict
10%inclusion56 decks572 decks
-5%synergy
Undying Malice
9.1%inclusion52 decks572 decks
-1%synergy
Bitter Triumph
8.6%inclusion49 decks572 decks
-1%synergy
Culling the Weak
8.2%inclusion47 decks572 decks
-8%synergy
Tragic Slip
7.5%inclusion43 decks572 decks
-12%synergy
Rush of Vitality
7.3%inclusion42 decks572 decks
7%synergy
Cut Down
7.2%inclusion41 decks572 decks
3%synergy
Undying Evil
7.0%inclusion40 decks572 decks
4%synergy
Soul Shatter
6.8%inclusion39 decks572 decks
-5%synergy
Unnatural Endurance
6.1%inclusion35 decks572 decks
6%synergy
Not Dead After All
5.8%inclusion33 decks572 decks
-6%synergy
Blood Pact
5.4%inclusion31 decks572 decks
1%synergy
Slaughter Pact
5.2%inclusion30 decks572 decks
3%synergy
Sorceries
Night's Whisper
47%inclusion266 decks572 decks
22%synergy
Crux of Fate
41%inclusion233 decks572 decks
39%synergy
Toxic Deluge
40%inclusion231 decks572 decks
4%synergy
Caress of Phyrexia
36%inclusion206 decks572 decks
35%synergy
Bubbling Muck
33%inclusion186 decks572 decks
17%synergy
Read the Bones
31%inclusion177 decks572 decks
14%synergy
Vat Emergence
26%inclusion149 decks572 decks
25%synergy
Damnation
26%inclusion149 decks572 decks
6%synergy
Reanimate
25%inclusion144 decks572 decks
-15%synergy
Diabolic Tutor
20%inclusion117 decks572 decks
6%synergy
Mutilate
18%inclusion103 decks572 decks
1%synergy
Spread the Sickness
18%inclusion102 decks572 decks
17%synergy
Insatiable Avarice
18%inclusion101 decks572 decks
6%synergy
Grim Tutor
16%inclusion92 decks572 decks
5%synergy
Exsanguinate
13%inclusion76 decks572 decks
-11%synergy
Black Sun's Zenith
13%inclusion74 decks572 decks
8%synergy
Blasphemous Edict
12%inclusion46 decks384 decks
-5%synergy
Geth's Summons
12%inclusion68 decks572 decks
11%synergy
Feed the Infection
10%inclusion57 decks572 decks
9%synergy
Beseech the Queen
7.3%inclusion42 decks572 decks
1%synergy
Syphon Mind
6.6%inclusion38 decks572 decks
-6%synergy
Profane Tutor
6.5%inclusion37 decks572 decks
2%synergy
In Garruk's Wake
6.1%inclusion35 decks572 decks
2%synergy
Torment of Hailfire
6.1%inclusion35 decks572 decks
-9%synergy
Fell
6.0%inclusion32 decks531 decks
3%synergy
Praetor's Grasp
5.9%inclusion34 decks572 decks
2%synergy
Gix's Command
5.1%inclusion29 decks572 decks
3%synergy
Utility Artifacts
Nightmare Lash
53%inclusion302 decks572 decks
51%synergy
Blackblade Reforged
52%inclusion296 decks572 decks
49%synergy
Lightning Greaves
50%inclusion285 decks572 decks
16%synergy
Fireshrieker
44%inclusion251 decks572 decks
42%synergy
Contagion Clasp
42%inclusion239 decks572 decks
40%synergy
Whispersilk Cloak
39%inclusion225 decks572 decks
33%synergy
Contagion Engine
37%inclusion210 decks572 decks
35%synergy
Sword of Truth and Justice
36%inclusion206 decks572 decks
35%synergy
Commander's Plate
36%inclusion205 decks572 decks
30%synergy
Shadowspear
27%inclusion154 decks572 decks
23%synergy
The Darkness Crystal
24%inclusion50 decks210 decks
4%synergy
Champion's Helm
23%inclusion132 decks572 decks
21%synergy
Leyline Axe
21%inclusion81 decks386 decks
20%synergy
Trailblazer's Boots
21%inclusion118 decks572 decks
18%synergy
Hero's Blade
19%inclusion107 decks572 decks
18%synergy
Sword of the Animist
17%inclusion100 decks572 decks
14%synergy
Brotherhood Regalia
16%inclusion91 decks553 decks
14%synergy
Cranial Plating
15%inclusion83 decks572 decks
11%synergy
Mithril Coat
14%inclusion80 decks572 decks
8%synergy
Sword of Feast and Famine
14%inclusion80 decks572 decks
12%synergy
Expedition Map
14%inclusion78 decks572 decks
2%synergy
Pact Weapon
14%inclusion78 decks572 decks
11%synergy
Throne of Geth
13%inclusion77 decks572 decks
13%synergy
Wayfarer's Bauble
13%inclusion73 decks572 decks
-2%synergy
Genji Glove
12%inclusion25 decks203 decks
11%synergy
Grafted Exoskeleton
11%inclusion64 decks572 decks
10%synergy
Inquisitor's Flail
10%inclusion60 decks572 decks
10%synergy
Strata Scythe
10%inclusion59 decks572 decks
10%synergy
Sword of Vengeance
10%inclusion56 decks572 decks
9%synergy
Hammer of Nazahn
10%inclusion56 decks572 decks
9%synergy
Loxodon Warhammer
10%inclusion55 decks572 decks
8%synergy
Basilisk Collar
9.4%inclusion54 decks572 decks
7%synergy
Prowler's Helm
8.6%inclusion49 decks572 decks
8%synergy
Helm of the Host
8.2%inclusion47 decks572 decks
7%synergy
Vorpal Sword
8.2%inclusion47 decks572 decks
4%synergy
Doc Ock's Tentacles
8.0%inclusion14 decks174 decks
8%synergy
Bontu's Monument
7.9%inclusion45 decks572 decks
-21%synergy
Darksteel Plate
7.7%inclusion44 decks572 decks
6%synergy
Sword of Wealth and Power
7.3%inclusion42 decks572 decks
7%synergy
Sensei's Divining Top
7.2%inclusion41 decks572 decks
-1%synergy
Grafted Wargear
7.2%inclusion41 decks572 decks
7%synergy
Pip-Boy 3000
6.8%inclusion39 decks572 decks
6%synergy
O-Naginata
6.6%inclusion38 decks572 decks
6%synergy
Whip of Erebos
6.3%inclusion36 decks572 decks
-5%synergy
Manifold Key
5.9%inclusion34 decks572 decks
4%synergy
Buster Sword
5.8%inclusion12 decks207 decks
5%synergy
Sword of Fire and Ice
5.8%inclusion33 decks572 decks
5%synergy
Thran Power Suit
5.2%inclusion30 decks572 decks
5%synergy
Nettlecyst
5.1%inclusion29 decks572 decks
4%synergy
Silver Shroud Costume
5.1%inclusion29 decks572 decks
4%synergy
Enchantments
Necrogen Communion
50%inclusion285 decks572 decks
48%synergy
Unspeakable Symbol
35%inclusion202 decks572 decks
34%synergy
Kaya's Ghostform
30%inclusion172 decks572 decks
20%synergy
Black Market Connections
24%inclusion135 decks572 decks
0%synergy
Bad Moon
20%inclusion113 decks572 decks
17%synergy
Fungal Fortitude
17%inclusion97 decks572 decks
16%synergy
Phyresis
17%inclusion96 decks572 decks
15%synergy
No Mercy
16%inclusion91 decks572 decks
9%synergy
Relic Putrescence
14%inclusion78 decks572 decks
13%synergy
Endless Scream
13%inclusion72 decks572 decks
12%synergy
Dauthi Embrace
12%inclusion66 decks572 decks
10%synergy
Shade's Form
9.4%inclusion54 decks572 decks
9%synergy
Snake Cult Initiation
8.9%inclusion51 decks572 decks
9%synergy
Super State
8.8%inclusion17 decks194 decks
8%synergy
Animate Dead
7.9%inclusion45 decks572 decks
-9%synergy
Black Market
6.3%inclusion36 decks572 decks
-15%synergy
Greed
5.9%inclusion34 decks572 decks
-1%synergy
Glistening Oil
5.8%inclusion33 decks572 decks
5%synergy
The Meathook Massacre
5.1%inclusion29 decks572 decks
-12%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion264 decks572 decks
44%synergy
Liliana of the Dark Realms
31%inclusion179 decks572 decks
17%synergy
Utility Lands
Rogue's Passage
65%inclusion372 decks572 decks
46%synergy
Cabal Coffers
62%inclusion355 decks572 decks
7%synergy
Bojuka Bog
47%inclusion271 decks572 decks
0%synergy
Urborg, Tomb of Yawgmoth
45%inclusion257 decks572 decks
7%synergy
Shizo, Death's Storehouse
43%inclusion244 decks572 decks
33%synergy
Inkmoth Nexus
39%inclusion224 decks572 decks
38%synergy
Cabal Stronghold
36%inclusion207 decks572 decks
2%synergy
Nykthos, Shrine to Nyx
24%inclusion138 decks572 decks
-6%synergy
Cathedral of War
19%inclusion111 decks572 decks
19%synergy
The Black Gate
18%inclusion103 decks572 decks
15%synergy
Castle Locthwain
17%inclusion96 decks572 decks
0%synergy
Reliquary Tower
16%inclusion93 decks572 decks
-14%synergy
War Room
16%inclusion89 decks572 decks
0%synergy
Command Beacon
15%inclusion87 decks572 decks
7%synergy
Witch's Cottage
14%inclusion78 decks572 decks
-11%synergy
Mortuary Mire
11%inclusion64 decks572 decks
-2%synergy
Urza's Saga
11%inclusion64 decks572 decks
3%synergy
Minas Morgul, Dark Fortress
10%inclusion59 decks572 decks
7%synergy
Temple of the False God
9.4%inclusion54 decks572 decks
2%synergy
Takenuma, Abandoned Mire
7.9%inclusion45 decks572 decks
-8%synergy
Lake of the Dead
7.9%inclusion45 decks572 decks
3%synergy
Strip Mine
7.3%inclusion42 decks572 decks
4%synergy
Barren Moor
7.2%inclusion41 decks572 decks
-2%synergy
Maze of Ith
6.1%inclusion35 decks572 decks
3%synergy
Buried Ruin
5.9%inclusion34 decks572 decks
1%synergy
Thespian's Stage
5.9%inclusion34 decks572 decks
1%synergy
Phyrexian Tower
5.9%inclusion34 decks572 decks
-20%synergy
Vault of Whispers
5.8%inclusion33 decks572 decks
1%synergy
Spymaster's Vault
5.1%inclusion29 decks572 decks
-5%synergy
Mana Artifacts
Sol Ring
90%inclusion513 decks572 decks
4%synergy
Arcane Signet
65%inclusion374 decks572 decks
4%synergy
Glistening Sphere
44%inclusion253 decks572 decks
43%synergy
Mind Stone
33%inclusion190 decks572 decks
5%synergy
Charcoal Diamond
31%inclusion176 decks572 decks
9%synergy
Staff of Compleation
29%inclusion164 decks572 decks
27%synergy
Heraldic Banner
19%inclusion108 decks572 decks
14%synergy
Thought Vessel
17%inclusion100 decks572 decks
-8%synergy
Fellwar Stone
16%inclusion91 decks572 decks
2%synergy
Caged Sun
15%inclusion86 decks572 decks
4%synergy
The Soul Stone
14%inclusion27 decks188 decks
0%synergy
Lotus Petal
13%inclusion76 decks572 decks
6%synergy
Throne of Eldraine
11%inclusion63 decks572 decks
1%synergy
Everflowing Chalice
10%inclusion57 decks572 decks
4%synergy
Commander's Sphere
10%inclusion56 decks572 decks
1%synergy
Mox Opal
9.4%inclusion54 decks572 decks
6%synergy
Thran Dynamo
9.3%inclusion53 decks572 decks
3%synergy
Gilded Lotus
6.6%inclusion38 decks572 decks
1%synergy
Sceptre of Eternal Glory
6.6%inclusion38 decks572 decks
-2%synergy
Worn Powerstone
5.9%inclusion34 decks572 decks
2%synergy
Extraplanar Lens
5.8%inclusion33 decks572 decks
1%synergy
Mox Amber
5.8%inclusion33 decks572 decks
2%synergy
Phyrexian Atlas
5.4%inclusion31 decks572 decks
5%synergy
Lands
Swamp
95%inclusion541 decks572 decks
-1%synergy
Myriad Landscape
24%inclusion140 decks572 decks
-1%synergy
Malakir Rebirth
19%inclusion109 decks572 decks
-4%synergy
Cavern of Souls
15%inclusion86 decks572 decks
8%synergy
Mirrex
15%inclusion83 decks572 decks
14%synergy
Fell the Profane
14%inclusion79 decks572 decks
-5%synergy
The Seedcore
7.5%inclusion43 decks572 decks
7%synergy
Opal Palace
7.5%inclusion43 decks572 decks
7%synergy
Urza's Cave
7.2%inclusion41 decks572 decks
-1%synergy
Snow-Covered Swamp
6.1%inclusion35 decks572 decks
0%synergy
Command Tower
5.4%inclusion31 decks572 decks
0%synergy
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