Skithiryx, the Blight Dragon (Commander) - Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #781
694decks
As CommanderAs CardAverage DeckDecks
Bracket
All12345
Budget
Any$$$$
Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
Deck Filters
Cardsphere
Archidekt
Commander Spellbook
Moxfield
Scryfall
New Cards
High Synergy Cards
Top Cards
Game Changers
Creatures
Instants
Sorceries
Utility Artifacts
Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
Back to Top
Bitterbloom Bearer
3.3%inclusion3 decks91 decks
1%synergy
Bender's Waterskin
2.6%inclusion3 decks114 decks
2%synergy
Swampsnare Trap
1.6%inclusion1 decks64 decks
1%synergy
Koh, the Face Stealer
1.6%inclusion1 decks64 decks
0%synergy
Realm of Koh
1.6%inclusion1 decks64 decks
-2%synergy
High Synergy Cards
Plague Stinger
81%inclusion563 decks694 decks
80%synergy
Plague Myr
78%inclusion544 decks694 decks
77%synergy
Ichor Rats
79%inclusion546 decks694 decks
76%synergy
Hand of the Praetors
76%inclusion528 decks694 decks
75%synergy
Infectious Inquiry
76%inclusion529 decks694 decks
73%synergy
Vraska's Fall
71%inclusion491 decks694 decks
67%synergy
Whispering Specter
67%inclusion468 decks694 decks
67%synergy
Karn's Bastion
69%inclusion478 decks694 decks
65%synergy
Phyrexian Crusader
65%inclusion452 decks694 decks
64%synergy
Drown in Ichor
66%inclusion457 decks694 decks
61%synergy
Top Cards
Dark Ritual
79%inclusion548 decks694 decks
12%synergy
Lashwrithe
64%inclusion445 decks694 decks
60%synergy
Swiftfoot Boots
63%inclusion439 decks694 decks
32%synergy
Jet Medallion
63%inclusion434 decks694 decks
2%synergy
Blightbelly Rat
61%inclusion426 decks694 decks
58%synergy
Phyrexian Arena
61%inclusion424 decks694 decks
21%synergy
Crypt Ghast
61%inclusion422 decks694 decks
12%synergy
Phyresis Outbreak
61%inclusion420 decks694 decks
59%synergy
Sign in Blood
58%inclusion401 decks694 decks
22%synergy
Nightmare Lash
57%inclusion398 decks694 decks
55%synergy
Game Changers
Demonic Tutor
42%inclusion292 decks694 decks
14%synergy
Vampiric Tutor
31%inclusion215 decks694 decks
10%synergy
Necropotence
22%inclusion153 decks694 decks
7%synergy
Ancient Tomb
21%inclusion148 decks694 decks
9%synergy
Bolas's Citadel
16%inclusion113 decks694 decks
-13%synergy
Mana Vault
15%inclusion105 decks694 decks
8%synergy
Opposition Agent
13%inclusion90 decks694 decks
3%synergy
The One Ring
12%inclusion80 decks694 decks
2%synergy
Chrome Mox
11%inclusion73 decks694 decks
4%synergy
Imperial Seal
9.2%inclusion64 decks694 decks
2%synergy
Creatures
Reaper of Sheoldred
54%inclusion373 decks694 decks
53%synergy
Ichorclaw Myr
47%inclusion325 decks694 decks
46%synergy
Flensermite
45%inclusion313 decks694 decks
45%synergy
Core Prowler
44%inclusion306 decks694 decks
43%synergy
Bilious Skulldweller
44%inclusion303 decks694 decks
43%synergy
Corpse Cur
43%inclusion299 decks694 decks
43%synergy
Flesh-Eater Imp
39%inclusion269 decks694 decks
38%synergy
Pestilent Syphoner
38%inclusion264 decks694 decks
37%synergy
Septic Rats
36%inclusion252 decks694 decks
34%synergy
Phyrexian Obliterator
35%inclusion241 decks694 decks
24%synergy
K'rrik, Son of Yawgmoth
31%inclusion213 decks694 decks
12%synergy
Necropede
29%inclusion198 decks694 decks
28%synergy
Myr Convert
27%inclusion187 decks694 decks
26%synergy
Yawgmoth, Thran Physician
24%inclusion168 decks694 decks
14%synergy
Blightsteel Colossus
22%inclusion154 decks694 decks
22%synergy
Solemn Simulacrum
22%inclusion152 decks694 decks
-1%synergy
Gray Merchant of Asphodel
22%inclusion151 decks694 decks
-30%synergy
Contagious Nim
21%inclusion146 decks694 decks
21%synergy
Leaden Myr
20%inclusion136 decks694 decks
13%synergy
Gulping Scraptrap
18%inclusion128 decks694 decks
18%synergy
Blackcleave Goblin
18%inclusion122 decks694 decks
17%synergy
Phyrexian Juggernaut
16%inclusion109 decks694 decks
16%synergy
Magus of the Coffers
15%inclusion103 decks694 decks
8%synergy
Massacre Girl, Known Killer
15%inclusion101 decks694 decks
11%synergy
Defiler of Flesh
14%inclusion98 decks694 decks
10%synergy
Dauthi Voidwalker
14%inclusion96 decks694 decks
-2%synergy
Necroskitter
14%inclusion96 decks694 decks
10%synergy
Sheoldred, Whispering One
13%inclusion91 decks694 decks
1%synergy
Phyrexian Vatmother
13%inclusion90 decks694 decks
13%synergy
Dread Presence
13%inclusion89 decks694 decks
-2%synergy
Toxic Nim
12%inclusion86 decks694 decks
12%synergy
Grafted Butcher
12%inclusion84 decks694 decks
12%synergy
Sheoldred's Headcleaver
12%inclusion80 decks694 decks
11%synergy
Filth
11%inclusion79 decks694 decks
9%synergy
Dark Confidant
11%inclusion77 decks694 decks
4%synergy
Silent Arbiter
10%inclusion68 decks694 decks
8%synergy
Phyrexian Digester
9.4%inclusion65 decks694 decks
9%synergy
Nirkana Revenant
9.4%inclusion65 decks694 decks
-2%synergy
Sheoldred, the Apocalypse
9.1%inclusion63 decks694 decks
-6%synergy
Burnished Hart
8.6%inclusion60 decks694 decks
1%synergy
Maha, Its Feathers Night
8.1%inclusion39 decks481 decks
3%synergy
Nimraiser Paladin
8.1%inclusion56 decks694 decks
8%synergy
Orcish Bowmasters
8.1%inclusion56 decks694 decks
-6%synergy
Vector Asp
7.8%inclusion54 decks694 decks
8%synergy
Massacre Wurm
6.9%inclusion48 decks694 decks
-11%synergy
Swamp Mosquito
6.9%inclusion48 decks694 decks
7%synergy
Gwenom, Remorseless
6.9%inclusion8 decks116 decks
4%synergy
Brass Squire
6.8%inclusion47 decks694 decks
6%synergy
Scourge Servant
6.6%inclusion46 decks694 decks
7%synergy
Surge Conductor
6.4%inclusion8 decks125 decks
6%synergy
Instants
Howl from Beyond
52%inclusion358 decks694 decks
51%synergy
Whisper of the Dross
47%inclusion326 decks694 decks
44%synergy
Defile
44%inclusion308 decks694 decks
7%synergy
Go for the Throat
40%inclusion281 decks694 decks
17%synergy
Tainted Strike
38%inclusion264 decks694 decks
35%synergy
Grim Affliction
36%inclusion252 decks694 decks
34%synergy
Deadly Rollick
33%inclusion227 decks694 decks
9%synergy
Infernal Grasp
32%inclusion225 decks694 decks
7%synergy
Withering Torment
29%inclusion118 decks403 decks
-2%synergy
Dismember
29%inclusion200 decks694 decks
18%synergy
Cabal Ritual
27%inclusion188 decks694 decks
9%synergy
Imp's Mischief
27%inclusion185 decks694 decks
3%synergy
Sugar Rush
24%inclusion169 decks694 decks
24%synergy
Supernatural Stamina
22%inclusion154 decks694 decks
15%synergy
Hatred
20%inclusion138 decks694 decks
19%synergy
Astarion's Thirst
19%inclusion133 decks694 decks
18%synergy
Virulent Wound
18%inclusion128 decks694 decks
18%synergy
Sudden Spoiling
18%inclusion126 decks694 decks
9%synergy
Malakir Rebirth
18%inclusion122 decks694 decks
-5%synergy
Consuming Corruption
18%inclusion93 decks531 decks
1%synergy
Snuff Out
17%inclusion118 decks694 decks
4%synergy
Archenemy's Charm
17%inclusion21 decks125 decks
8%synergy
Hero's Downfall
16%inclusion110 decks694 decks
9%synergy
Doom Blade
15%inclusion105 decks694 decks
7%synergy
Fell the Profane
14%inclusion75 decks537 decks
-5%synergy
Force of Despair
13%inclusion92 decks694 decks
5%synergy
Unlikely Aid
13%inclusion89 decks694 decks
12%synergy
Anoint with Affliction
12%inclusion86 decks694 decks
12%synergy
Murder
12%inclusion86 decks694 decks
2%synergy
Baleful Mastery
12%inclusion82 decks694 decks
3%synergy
Darkness
10%inclusion70 decks694 decks
1%synergy
Withering Boon
10%inclusion70 decks694 decks
6%synergy
Sheoldred's Edict
9.4%inclusion65 decks694 decks
-5%synergy
Undying Malice
8.6%inclusion60 decks694 decks
-1%synergy
Culling the Weak
8.2%inclusion57 decks694 decks
-7%synergy
Bitter Triumph
8.2%inclusion57 decks694 decks
-2%synergy
Tragic Slip
7.6%inclusion53 decks694 decks
-13%synergy
Rush of Vitality
7.6%inclusion53 decks694 decks
7%synergy
Not Dead After All
7.5%inclusion52 decks694 decks
-4%synergy
Undying Evil
7.5%inclusion52 decks694 decks
4%synergy
Cut Down
7.3%inclusion51 decks694 decks
3%synergy
Soul Shatter
6.8%inclusion47 decks694 decks
-5%synergy
Unnatural Endurance
6.6%inclusion46 decks694 decks
6%synergy
Slaughter Pact
6.2%inclusion43 decks694 decks
3%synergy
Overkill
5.7%inclusion8 decks141 decks
-2%synergy
Blood Pact
5.5%inclusion38 decks694 decks
1%synergy
Sorceries
Feed the Swarm
54%inclusion377 decks694 decks
3%synergy
Night's Whisper
47%inclusion325 decks694 decks
22%synergy
Crux of Fate
41%inclusion283 decks694 decks
39%synergy
Toxic Deluge
40%inclusion278 decks694 decks
3%synergy
Caress of Phyrexia
38%inclusion265 decks694 decks
38%synergy
Read the Bones
33%inclusion232 decks694 decks
16%synergy
Bubbling Muck
30%inclusion209 decks694 decks
14%synergy
Damnation
27%inclusion187 decks694 decks
6%synergy
Vat Emergence
24%inclusion164 decks694 decks
22%synergy
Reanimate
23%inclusion163 decks694 decks
-16%synergy
Diabolic Tutor
23%inclusion158 decks694 decks
8%synergy
Spread the Sickness
18%inclusion128 decks694 decks
18%synergy
Insatiable Avarice
18%inclusion111 decks617 decks
6%synergy
Mutilate
18%inclusion123 decks694 decks
-1%synergy
Grim Tutor
16%inclusion110 decks694 decks
4%synergy
Blasphemous Edict
13%inclusion44 decks327 decks
-4%synergy
Exsanguinate
13%inclusion87 decks694 decks
-12%synergy
Geth's Summons
13%inclusion87 decks694 decks
12%synergy
Black Sun's Zenith
12%inclusion81 decks694 decks
6%synergy
Feed the Infection
9.1%inclusion63 decks694 decks
8%synergy
Profane Tutor
7.5%inclusion52 decks694 decks
3%synergy
Syphon Mind
7.3%inclusion51 decks694 decks
-6%synergy
Beseech the Queen
7.3%inclusion51 decks694 decks
1%synergy
In Garruk's Wake
7.2%inclusion50 decks694 decks
3%synergy
Torment of Hailfire
6.5%inclusion45 decks694 decks
-9%synergy
Fell
6.2%inclusion30 decks481 decks
3%synergy
Praetor's Grasp
5.3%inclusion37 decks694 decks
1%synergy
Utility Artifacts
Blackblade Reforged
52%inclusion362 decks694 decks
49%synergy
Lightning Greaves
51%inclusion357 decks694 decks
18%synergy
Fireshrieker
46%inclusion319 decks694 decks
44%synergy
Contagion Clasp
42%inclusion292 decks694 decks
39%synergy
Whispersilk Cloak
40%inclusion280 decks694 decks
34%synergy
Contagion Engine
37%inclusion257 decks694 decks
35%synergy
Sword of Truth and Justice
37%inclusion254 decks694 decks
36%synergy
Commander's Plate
36%inclusion248 decks694 decks
30%synergy
Shadowspear
28%inclusion196 decks694 decks
25%synergy
The Darkness Crystal
25%inclusion37 decks147 decks
5%synergy
Leyline Axe
22%inclusion74 decks329 decks
22%synergy
Champion's Helm
21%inclusion143 decks694 decks
19%synergy
Hero's Blade
19%inclusion134 decks694 decks
19%synergy
Trailblazer's Boots
19%inclusion133 decks694 decks
17%synergy
Brotherhood Regalia
17%inclusion87 decks503 decks
15%synergy
Sword of the Animist
17%inclusion116 decks694 decks
13%synergy
Mithril Coat
15%inclusion103 decks694 decks
9%synergy
Cranial Plating
15%inclusion103 decks694 decks
11%synergy
Pact Weapon
15%inclusion102 decks694 decks
12%synergy
Throne of Geth
14%inclusion96 decks694 decks
14%synergy
Genji Glove
14%inclusion19 decks140 decks
12%synergy
Sword of Feast and Famine
14%inclusion94 decks694 decks
12%synergy
Expedition Map
13%inclusion91 decks694 decks
1%synergy
Wayfarer's Bauble
13%inclusion89 decks694 decks
-3%synergy
Doc Ock's Tentacles
12%inclusion12 decks102 decks
12%synergy
Strata Scythe
11%inclusion75 decks694 decks
10%synergy
Grafted Exoskeleton
11%inclusion73 decks694 decks
9%synergy
Inquisitor's Flail
10%inclusion71 decks694 decks
10%synergy
Sword of Vengeance
10%inclusion67 decks694 decks
9%synergy
Hammer of Nazahn
8.9%inclusion62 decks694 decks
8%synergy
Loxodon Warhammer
8.8%inclusion61 decks694 decks
7%synergy
Pip-Boy 3000
8.5%inclusion56 decks661 decks
8%synergy
Prowler's Helm
8.4%inclusion58 decks694 decks
7%synergy
Bontu's Monument
8.4%inclusion58 decks694 decks
-20%synergy
Helm of the Host
8.1%inclusion56 decks694 decks
7%synergy
Darksteel Plate
7.9%inclusion55 decks694 decks
6%synergy
Basilisk Collar
7.6%inclusion53 decks694 decks
5%synergy
Sensei's Divining Top
7.5%inclusion52 decks694 decks
-1%synergy
Grafted Wargear
7.5%inclusion52 decks694 decks
7%synergy
Sword of Wealth and Power
7.4%inclusion49 decks662 decks
7%synergy
Vorpal Sword
7.1%inclusion49 decks694 decks
3%synergy
Buster Sword
6.9%inclusion10 decks144 decks
6%synergy
O-Naginata
6.5%inclusion45 decks694 decks
6%synergy
Whip of Erebos
6.3%inclusion44 decks694 decks
-4%synergy
Sword of Fire and Ice
5.5%inclusion38 decks694 decks
5%synergy
Manifold Key
5.3%inclusion37 decks694 decks
4%synergy
Mask of Avacyn
5.2%inclusion36 decks694 decks
4%synergy
Decimator Web
5.2%inclusion36 decks694 decks
5%synergy
Enchantments
Necrogen Communion
50%inclusion349 decks694 decks
48%synergy
Unspeakable Symbol
39%inclusion271 decks694 decks
38%synergy
Kaya's Ghostform
30%inclusion207 decks694 decks
20%synergy
Black Market Connections
22%inclusion152 decks694 decks
-1%synergy
Bad Moon
21%inclusion144 decks694 decks
17%synergy
Fungal Fortitude
18%inclusion127 decks694 decks
17%synergy
Phyresis
16%inclusion108 decks694 decks
13%synergy
No Mercy
15%inclusion106 decks694 decks
8%synergy
Relic Putrescence
15%inclusion104 decks694 decks
15%synergy
Endless Scream
15%inclusion101 decks694 decks
14%synergy
Shade's Form
11%inclusion77 decks694 decks
10%synergy
Dauthi Embrace
11%inclusion74 decks694 decks
9%synergy
Snake Cult Initiation
7.9%inclusion55 decks694 decks
8%synergy
Super State
7.9%inclusion10 decks127 decks
8%synergy
Animate Dead
7.3%inclusion51 decks694 decks
-10%synergy
Black Market
7.1%inclusion49 decks694 decks
-14%synergy
Alien Symbiosis
6.9%inclusion7 decks102 decks
6%synergy
Greed
6.2%inclusion43 decks694 decks
-1%synergy
The Meathook Massacre
5.5%inclusion38 decks694 decks
-12%synergy
Glistening Oil
5.5%inclusion38 decks694 decks
5%synergy
Phyrexian Reclamation
5.2%inclusion36 decks694 decks
-5%synergy
Planeswalkers
Vraska, Betrayal's Sting
46%inclusion321 decks694 decks
43%synergy
Liliana of the Dark Realms
28%inclusion194 decks694 decks
14%synergy
Utility Lands
Rogue's Passage
67%inclusion465 decks694 decks
48%synergy
Cabal Coffers
62%inclusion429 decks694 decks
7%synergy
Bojuka Bog
48%inclusion334 decks694 decks
1%synergy
Urborg, Tomb of Yawgmoth
47%inclusion329 decks694 decks
10%synergy
Shizo, Death's Storehouse
45%inclusion311 decks694 decks
35%synergy
Inkmoth Nexus
41%inclusion287 decks694 decks
40%synergy
Cabal Stronghold
37%inclusion260 decks694 decks
2%synergy
Nykthos, Shrine to Nyx
25%inclusion175 decks694 decks
-5%synergy
The Black Gate
21%inclusion144 decks694 decks
17%synergy
Cathedral of War
19%inclusion132 decks694 decks
19%synergy
Castle Locthwain
17%inclusion120 decks694 decks
0%synergy
Command Beacon
17%inclusion117 decks694 decks
9%synergy
War Room
16%inclusion110 decks694 decks
-1%synergy
Reliquary Tower
14%inclusion100 decks694 decks
-17%synergy
Witch's Cottage
13%inclusion88 decks694 decks
-12%synergy
Minas Morgul, Dark Fortress
12%inclusion80 decks694 decks
8%synergy
Urza's Saga
11%inclusion79 decks694 decks
3%synergy
Mortuary Mire
10%inclusion70 decks694 decks
-3%synergy
Temple of the False God
9.4%inclusion65 decks694 decks
1%synergy
Lake of the Dead
9.1%inclusion63 decks694 decks
4%synergy
Strip Mine
8.6%inclusion60 decks694 decks
6%synergy
Takenuma, Abandoned Mire
8.4%inclusion58 decks694 decks
-8%synergy
Barren Moor
7.6%inclusion53 decks694 decks
-3%synergy
Maze of Ith
6.6%inclusion46 decks694 decks
3%synergy
Buried Ruin
6.2%inclusion43 decks694 decks
1%synergy
Phyrexian Tower
5.9%inclusion41 decks694 decks
-18%synergy
Thespian's Stage
5.8%inclusion40 decks694 decks
0%synergy
Spymaster's Vault
5.4%inclusion29 decks537 decks
-4%synergy
Homeward Path
5.0%inclusion35 decks694 decks
3%synergy
Mana Artifacts
Sol Ring
91%inclusion629 decks694 decks
4%synergy
Arcane Signet
65%inclusion452 decks694 decks
3%synergy
Glistening Sphere
46%inclusion321 decks694 decks
45%synergy
Mind Stone
33%inclusion229 decks694 decks
2%synergy
Charcoal Diamond
31%inclusion215 decks694 decks
8%synergy
Staff of Compleation
28%inclusion194 decks694 decks
26%synergy
Heraldic Banner
19%inclusion132 decks694 decks
13%synergy
The Soul Stone
18%inclusion21 decks119 decks
5%synergy
Caged Sun
17%inclusion120 decks694 decks
5%synergy
Thought Vessel
16%inclusion110 decks694 decks
-11%synergy
Fellwar Stone
15%inclusion102 decks694 decks
0%synergy
Lotus Petal
13%inclusion88 decks694 decks
5%synergy
Throne of Eldraine
11%inclusion79 decks694 decks
1%synergy
Commander's Sphere
11%inclusion75 decks694 decks
2%synergy
Mox Opal
10%inclusion70 decks694 decks
7%synergy
Everflowing Chalice
10%inclusion69 decks694 decks
4%synergy
Jeweled Lotus
8.9%inclusion62 decks694 decks
7%synergy
Thran Dynamo
7.5%inclusion52 decks694 decks
1%synergy
Mana Crypt
7.3%inclusion51 decks694 decks
5%synergy
Sceptre of Eternal Glory
6.6%inclusion46 decks694 decks
-3%synergy
Worn Powerstone
6.3%inclusion44 decks694 decks
2%synergy
Gilded Lotus
5.9%inclusion41 decks694 decks
0%synergy
Mox Diamond
5.6%inclusion39 decks694 decks
2%synergy
Nyx Lotus
5.5%inclusion38 decks694 decks
-1%synergy
Phyrexian Atlas
5.0%inclusion35 decks694 decks
5%synergy
Lands
Swamp
95%inclusion659 decks694 decks
0%synergy
Myriad Landscape
24%inclusion166 decks694 decks
-3%synergy
Malakir Rebirth
18%inclusion122 decks694 decks
-5%synergy
Cavern of Souls
16%inclusion111 decks694 decks
9%synergy
Mirrex
15%inclusion107 decks694 decks
15%synergy
Fell the Profane
14%inclusion75 decks537 decks
-5%synergy
Opal Palace
8.2%inclusion57 decks694 decks
7%synergy
Urza's Cave
7.6%inclusion43 decks568 decks
-1%synergy
The Seedcore
7.1%inclusion49 decks694 decks
7%synergy
Snow-Covered Swamp
5.9%inclusion41 decks694 decks
-1%synergy
Command Tower
5.2%inclusion36 decks694 decks
0%synergy
Polluted Delta
5.2%inclusion36 decks694 decks
2%synergy
Bloodstained Mire
5.2%inclusion36 decks694 decks
2%synergy
Verdant Catacombs
5.0%inclusion35 decks694 decks
2%synergy
About UsContactPrivacy PolicyTerms of Service
Space Cow MediaArchidektCardsphereCommander SpellbookFABRECSpellvoid
Space Cow MediaArchidektCommander's Herald
Commander SpellbookFABRECSpellvoid
EDHREC is unofficial Fan Content permitted under the Fan Content Policy. Not approved/endorsed by Wizards. Portions of the materials used are property of Wizards of the Coast. ©Wizards of the Coast LLC.
next@15 test