Skithiryx, the Blight Dragon (Commander) - Expensive Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #812
5decks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Vraska, Betrayal's Sting
100%inclusion5 decks5 decks
97%synergy
Contagion Engine
80%inclusion4 decks5 decks
78%synergy
Contagion Clasp
80%inclusion4 decks5 decks
78%synergy
Karn's Bastion
80%inclusion4 decks5 decks
76%synergy
Cabal Coffers
100%inclusion5 decks5 decks
45%synergy
Phyrexian Arena
80%inclusion4 decks5 decks
41%synergy
Crypt Ghast
80%inclusion4 decks5 decks
33%synergy
Bojuka Bog
80%inclusion4 decks5 decks
33%synergy
Dark Ritual
100%inclusion5 decks5 decks
33%synergy
Jet Medallion
80%inclusion4 decks5 decks
18%synergy
Creatures
Plague Stinger
60%inclusion3 decks5 decks
59%synergy
Plague Myr
60%inclusion3 decks5 decks
59%synergy
Phyrexian Obliterator
60%inclusion3 decks5 decks
49%synergy
Ichorclaw Myr
60%inclusion3 decks5 decks
60%synergy
Phyrexian Crusader
60%inclusion3 decks5 decks
59%synergy
Yawgmoth, Thran Physician
60%inclusion3 decks5 decks
50%synergy
Blightbelly Rat
60%inclusion3 decks5 decks
57%synergy
Hand of the Praetors
60%inclusion3 decks5 decks
59%synergy
Core Prowler
40%inclusion2 decks5 decks
39%synergy
Maha, Its Feathers Night
40%inclusion2 decks5 decks
36%synergy
Whispering Specter
40%inclusion2 decks5 decks
39%synergy
Reaper of Sheoldred
40%inclusion2 decks5 decks
39%synergy
Sheoldred, the Apocalypse
40%inclusion2 decks5 decks
25%synergy
Flensermite
40%inclusion2 decks5 decks
40%synergy
Bilious Skulldweller
40%inclusion2 decks5 decks
39%synergy
K'rrik, Son of Yawgmoth
40%inclusion2 decks5 decks
21%synergy
Massacre Girl, Known Killer
40%inclusion2 decks5 decks
37%synergy
Scheming Aspirant
40%inclusion2 decks5 decks
40%synergy
Blightsteel Colossus
40%inclusion2 decks5 decks
39%synergy
Dauthi Voidwalker
40%inclusion2 decks5 decks
24%synergy
Ichor Rats
40%inclusion2 decks5 decks
37%synergy
Virulent Silencer
25%inclusion1 decks4 decks
25%synergy
Hullcarver
25%inclusion1 decks4 decks
24%synergy
Azula, On the Hunt
25%inclusion1 decks4 decks
25%synergy
Raven Eagle
25%inclusion1 decks4 decks
24%synergy
Phyrexian Juggernaut
20%inclusion1 decks5 decks
20%synergy
Ozox, the Clattering King
20%inclusion1 decks5 decks
19%synergy
Dread Presence
20%inclusion1 decks5 decks
7%synergy
Foundry Inspector
20%inclusion1 decks5 decks
16%synergy
Vector Asp
20%inclusion1 decks5 decks
20%synergy
Grim Roustabout
20%inclusion1 decks5 decks
20%synergy
Pestilent Syphoner
20%inclusion1 decks5 decks
19%synergy
Dark Confidant
20%inclusion1 decks5 decks
12%synergy
Skeleton Crew
20%inclusion1 decks5 decks
19%synergy
Fain, the Broker
20%inclusion1 decks5 decks
19%synergy
Corrosive Mentor
20%inclusion1 decks5 decks
19%synergy
Gray Merchant of Asphodel
20%inclusion1 decks5 decks
-30%synergy
Drivnod, Carnage Dominus
20%inclusion1 decks5 decks
13%synergy
Carnifex Demon
20%inclusion1 decks5 decks
19%synergy
Restless Dead
20%inclusion1 decks5 decks
20%synergy
Archfiend of Ifnir
20%inclusion1 decks5 decks
18%synergy
Necroskitter
20%inclusion1 decks5 decks
17%synergy
Persistent Specimen
20%inclusion1 decks5 decks
18%synergy
Kjeldoran Dead
20%inclusion1 decks5 decks
20%synergy
Banehound
20%inclusion1 decks5 decks
19%synergy
Sifter of Skulls
20%inclusion1 decks5 decks
16%synergy
Varragoth, Bloodsky Sire
20%inclusion1 decks5 decks
16%synergy
Gisa, the Hellraiser
20%inclusion1 decks5 decks
16%synergy
Myr Convert
20%inclusion1 decks5 decks
19%synergy
Grafted Butcher
20%inclusion1 decks5 decks
20%synergy
Instants
Whisper of the Dross
60%inclusion3 decks5 decks
57%synergy
Tainted Strike
60%inclusion3 decks5 decks
57%synergy
Deadly Rollick
40%inclusion2 decks5 decks
14%synergy
Sheoldred's Edict
40%inclusion2 decks5 decks
25%synergy
Snuff Out
40%inclusion2 decks5 decks
26%synergy
Vraska's Fall
40%inclusion2 decks5 decks
37%synergy
Grim Affliction
40%inclusion2 decks5 decks
38%synergy
Deadly Dispute
40%inclusion2 decks5 decks
13%synergy
Defile
40%inclusion2 decks5 decks
5%synergy
Culling the Weak
40%inclusion2 decks5 decks
22%synergy
Malakir Rebirth
40%inclusion2 decks5 decks
16%synergy
Withering Torment
40%inclusion2 decks5 decks
8%synergy
Archenemy's Charm
25%inclusion1 decks4 decks
16%synergy
Fell the Profane
20%inclusion1 decks5 decks
0%synergy
Bone Harvest
20%inclusion1 decks5 decks
20%synergy
Go for the Throat
20%inclusion1 decks5 decks
-2%synergy
Imp's Mischief
20%inclusion1 decks5 decks
-5%synergy
Village Rites
20%inclusion1 decks5 decks
-6%synergy
Howl from Beyond
20%inclusion1 decks5 decks
19%synergy
Hatred
20%inclusion1 decks5 decks
19%synergy
Cabal Ritual
20%inclusion1 decks5 decks
1%synergy
Armor of Shadows
20%inclusion1 decks5 decks
18%synergy
Virulent Wound
20%inclusion1 decks5 decks
20%synergy
Withering Boon
20%inclusion1 decks5 decks
16%synergy
Bitter Triumph
20%inclusion1 decks5 decks
10%synergy
Infernal Grasp
20%inclusion1 decks5 decks
-5%synergy
Spoils of Evil
20%inclusion1 decks5 decks
20%synergy
Corrupted Conviction
20%inclusion1 decks5 decks
8%synergy
Tragic Slip
20%inclusion1 decks5 decks
1%synergy
Sorceries
Phyresis Outbreak
60%inclusion3 decks5 decks
58%synergy
Infectious Inquiry
60%inclusion3 decks5 decks
57%synergy
Night's Whisper
60%inclusion3 decks5 decks
35%synergy
Toxic Deluge
60%inclusion3 decks5 decks
23%synergy
Drown in Ichor
60%inclusion3 decks5 decks
56%synergy
Pox Plague
50%inclusion1 decks2 decks
45%synergy
Crux of Fate
40%inclusion2 decks5 decks
39%synergy
Feed the Swarm
40%inclusion2 decks5 decks
-10%synergy
Diabolic Intent
20%inclusion1 decks5 decks
5%synergy
Black Sun's Zenith
20%inclusion1 decks5 decks
15%synergy
Terisiare's Devastation
20%inclusion1 decks5 decks
19%synergy
Vat Emergence
20%inclusion1 decks5 decks
19%synergy
Bone Splinters
20%inclusion1 decks5 decks
18%synergy
Worthy Cost
20%inclusion1 decks5 decks
18%synergy
Spread the Sickness
20%inclusion1 decks5 decks
19%synergy
Profane Tutor
20%inclusion1 decks5 decks
16%synergy
Yawgmoth's Will
20%inclusion1 decks5 decks
17%synergy
Final Act
20%inclusion1 decks5 decks
18%synergy
Bubbling Muck
20%inclusion1 decks5 decks
4%synergy
Pox
20%inclusion1 decks5 decks
18%synergy
Agadeem's Awakening
20%inclusion1 decks5 decks
12%synergy
Mutilate
20%inclusion1 decks5 decks
5%synergy
Praetor's Grasp
20%inclusion1 decks5 decks
16%synergy
Smallpox
20%inclusion1 decks5 decks
15%synergy
Exsanguinate
20%inclusion1 decks5 decks
-5%synergy
Ambition's Cost
20%inclusion1 decks5 decks
17%synergy
Gix's Command
20%inclusion1 decks5 decks
18%synergy
Reanimate
20%inclusion1 decks5 decks
-21%synergy
In Garruk's Wake
20%inclusion1 decks5 decks
16%synergy
Insatiable Avarice
20%inclusion1 decks5 decks
9%synergy
Geth's Summons
20%inclusion1 decks5 decks
20%synergy
Sign in Blood
20%inclusion1 decks5 decks
-15%synergy
Final Vengeance
20%inclusion1 decks5 decks
18%synergy
Rise of the Dark Realms
20%inclusion1 decks5 decks
7%synergy
Breach the Multiverse
20%inclusion1 decks5 decks
14%synergy
Blood for Bones
20%inclusion1 decks5 decks
19%synergy
Utility Artifacts
Lashwrithe
60%inclusion3 decks5 decks
56%synergy
Fireshrieker
60%inclusion3 decks5 decks
58%synergy
Swiftfoot Boots
60%inclusion3 decks5 decks
29%synergy
Lightning Greaves
60%inclusion3 decks5 decks
26%synergy
Leyline Axe
40%inclusion2 decks5 decks
39%synergy
Skullclamp
40%inclusion2 decks5 decks
18%synergy
Sword of Truth and Justice
40%inclusion2 decks5 decks
39%synergy
Whispersilk Cloak
40%inclusion2 decks5 decks
34%synergy
Commander's Plate
40%inclusion2 decks5 decks
34%synergy
Blackblade Reforged
40%inclusion2 decks5 decks
37%synergy
Skeleton Key
20%inclusion1 decks5 decks
19%synergy
Nightmare Lash
20%inclusion1 decks5 decks
18%synergy
Throne of Geth
20%inclusion1 decks5 decks
20%synergy
Flayer Husk
20%inclusion1 decks5 decks
20%synergy
Trailblazer's Boots
20%inclusion1 decks5 decks
18%synergy
Nim Deathmantle
20%inclusion1 decks5 decks
17%synergy
Wishclaw Talisman
20%inclusion1 decks5 decks
13%synergy
Shadowspear
20%inclusion1 decks5 decks
16%synergy
Vanquisher's Banner
20%inclusion1 decks5 decks
16%synergy
Phyrexian Altar
20%inclusion1 decks5 decks
6%synergy
Bontu's Monument
20%inclusion1 decks5 decks
-8%synergy
Door of Destinies
20%inclusion1 decks5 decks
18%synergy
Silver Shroud Costume
20%inclusion1 decks5 decks
19%synergy
Pact Weapon
20%inclusion1 decks5 decks
18%synergy
Tome of Legends
20%inclusion1 decks5 decks
19%synergy
Batterskull
20%inclusion1 decks5 decks
20%synergy
Brotherhood Regalia
20%inclusion1 decks5 decks
17%synergy
Adaptive Omnitool
20%inclusion1 decks5 decks
20%synergy
Enchantments
Phyresis
40%inclusion2 decks5 decks
38%synergy
Phyrexian Scriptures
20%inclusion1 decks5 decks
19%synergy
Feast of the Unicorn
20%inclusion1 decks5 decks
20%synergy
Open the Graves
20%inclusion1 decks5 decks
17%synergy
Gift of Doom
20%inclusion1 decks5 decks
19%synergy
Fear
20%inclusion1 decks5 decks
20%synergy
Blowfly Infestation
20%inclusion1 decks5 decks
18%synergy
Glistening Oil
20%inclusion1 decks5 decks
19%synergy
Necrosynthesis
20%inclusion1 decks5 decks
19%synergy
Grave Pact
20%inclusion1 decks5 decks
1%synergy
Grave Servitude
20%inclusion1 decks5 decks
20%synergy
Corpses of the Lost
20%inclusion1 decks5 decks
19%synergy
Dictate of Erebos
20%inclusion1 decks5 decks
9%synergy
Thrull Retainer
20%inclusion1 decks5 decks
20%synergy
Soul Kiss
20%inclusion1 decks5 decks
20%synergy
Phyrexian Boon
20%inclusion1 decks5 decks
20%synergy
Eternal Thirst
20%inclusion1 decks5 decks
18%synergy
Unspeakable Symbol
20%inclusion1 decks5 decks
19%synergy
Kaya's Ghostform
20%inclusion1 decks5 decks
10%synergy
Dauthi Embrace
20%inclusion1 decks5 decks
18%synergy
Black Market Connections
20%inclusion1 decks5 decks
-5%synergy
Bad Moon
20%inclusion1 decks5 decks
17%synergy
Necrogen Communion
20%inclusion1 decks5 decks
18%synergy
Planeswalkers
Liliana of the Dark Realms
20%inclusion1 decks5 decks
6%synergy
Utility Lands
Shizo, Death's Storehouse
60%inclusion3 decks5 decks
50%synergy
Inkmoth Nexus
60%inclusion3 decks5 decks
59%synergy
Nykthos, Shrine to Nyx
60%inclusion3 decks5 decks
30%synergy
Rogue's Passage
60%inclusion3 decks5 decks
41%synergy
Cabal Stronghold
40%inclusion2 decks5 decks
6%synergy
Phyrexian Tower
40%inclusion2 decks5 decks
14%synergy
Urborg, Tomb of Yawgmoth
40%inclusion2 decks5 decks
2%synergy
Secluded Starforge
25%inclusion1 decks4 decks
25%synergy
Witch's Clinic
20%inclusion1 decks5 decks
18%synergy
Vault of Whispers
20%inclusion1 decks5 decks
14%synergy
Barren Moor
20%inclusion1 decks5 decks
11%synergy
Treasure Vault
20%inclusion1 decks5 decks
19%synergy
Crypt of Agadeem
20%inclusion1 decks5 decks
8%synergy
Cathedral of War
20%inclusion1 decks5 decks
20%synergy
Crystal Vein
20%inclusion1 decks5 decks
17%synergy
Witch's Cottage
20%inclusion1 decks5 decks
-4%synergy
War Room
20%inclusion1 decks5 decks
4%synergy
Command Beacon
20%inclusion1 decks5 decks
12%synergy
Tomb Fortress
20%inclusion1 decks5 decks
16%synergy
Takenuma, Abandoned Mire
20%inclusion1 decks5 decks
4%synergy
Ifnir Deadlands
20%inclusion1 decks5 decks
19%synergy
Muraganda Raceway
20%inclusion1 decks5 decks
18%synergy
Castle Locthwain
20%inclusion1 decks5 decks
3%synergy
Everglades
20%inclusion1 decks5 decks
19%synergy
Spawning Pool
20%inclusion1 decks5 decks
20%synergy
Hidden Necropolis
20%inclusion1 decks5 decks
19%synergy
Mana Artifacts
Sol Ring
100%inclusion5 decks5 decks
15%synergy
Arcane Signet
60%inclusion3 decks5 decks
-1%synergy
Staff of Compleation
60%inclusion3 decks5 decks
58%synergy
Glistening Sphere
40%inclusion2 decks5 decks
39%synergy
Fellwar Stone
40%inclusion2 decks5 decks
26%synergy
Mind Stone
40%inclusion2 decks5 decks
12%synergy
Wickersmith's Tools
33%inclusion1 decks3 decks
33%synergy
The Soul Stone
25%inclusion1 decks4 decks
9%synergy
Charcoal Diamond
20%inclusion1 decks5 decks
-2%synergy
Lotus Petal
20%inclusion1 decks5 decks
12%synergy
Heraldic Banner
20%inclusion1 decks5 decks
15%synergy
Thought Vessel
20%inclusion1 decks5 decks
-4%synergy
Mox Opal
20%inclusion1 decks5 decks
17%synergy
Lands
Swamp
100%inclusion5 decks5 decks
5%synergy
Myriad Landscape
40%inclusion2 decks5 decks
16%synergy
Mirrex
40%inclusion2 decks5 decks
39%synergy
Malakir Rebirth
40%inclusion2 decks5 decks
16%synergy
Fell the Profane
20%inclusion1 decks5 decks
0%synergy
Agadeem's Awakening
20%inclusion1 decks5 decks
12%synergy
Verdant Catacombs
20%inclusion1 decks5 decks
16%synergy
Boggart Trawler
20%inclusion1 decks5 decks
11%synergy
Cavern of Souls
20%inclusion1 decks5 decks
13%synergy
Marsh Flats
20%inclusion1 decks5 decks
16%synergy
Polluted Delta
20%inclusion1 decks5 decks
16%synergy
Bloodstained Mire
20%inclusion1 decks5 decks
16%synergy
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