Skithiryx, the Blight Dragon (Commander) - Expensive Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
3decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Lands
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Crypt Ghast
100%inclusion3 decks3 decks
52%synergy
Plague Stinger
67%inclusion2 decks3 decks
66%synergy
Core Prowler
67%inclusion2 decks3 decks
66%synergy
Whispering Specter
67%inclusion2 decks3 decks
66%synergy
Magus of the Coffers
67%inclusion2 decks3 decks
60%synergy
Reaper of Sheoldred
67%inclusion2 decks3 decks
66%synergy
Plague Myr
67%inclusion2 decks3 decks
65%synergy
Phyrexian Obliterator
67%inclusion2 decks3 decks
56%synergy
Flensermite
67%inclusion2 decks3 decks
66%synergy
Myr Convert
67%inclusion2 decks3 decks
66%synergy
Nirkana Revenant
67%inclusion2 decks3 decks
55%synergy
Ichorclaw Myr
67%inclusion2 decks3 decks
66%synergy
Corpse Cur
67%inclusion2 decks3 decks
66%synergy
Phyrexian Crusader
67%inclusion2 decks3 decks
66%synergy
Yawgmoth, Thran Physician
67%inclusion2 decks3 decks
56%synergy
Blightbelly Rat
67%inclusion2 decks3 decks
63%synergy
Flesh-Eater Imp
67%inclusion2 decks3 decks
66%synergy
Hand of the Praetors
67%inclusion2 decks3 decks
66%synergy
Ichor Rats
67%inclusion2 decks3 decks
64%synergy
Solemn Simulacrum
33%inclusion1 decks3 decks
10%synergy
Contagious Nim
33%inclusion1 decks3 decks
33%synergy
Korlash, Heir to Blackblade
33%inclusion1 decks3 decks
33%synergy
Murderous Rider
33%inclusion1 decks3 decks
27%synergy
Blackcleave Goblin
33%inclusion1 decks3 decks
33%synergy
Dread Presence
33%inclusion1 decks3 decks
18%synergy
Pestilent Syphoner
33%inclusion1 decks3 decks
33%synergy
Silent Arbiter
33%inclusion1 decks3 decks
32%synergy
Dark Confidant
33%inclusion1 decks3 decks
26%synergy
Sheoldred, the Apocalypse
33%inclusion1 decks3 decks
18%synergy
Necroskitter
33%inclusion1 decks3 decks
30%synergy
Unstoppable Slasher
33%inclusion1 decks3 decks
28%synergy
Bilious Skulldweller
33%inclusion1 decks3 decks
32%synergy
Sheoldred, Whispering One
33%inclusion1 decks3 decks
21%synergy
Gix, Yawgmoth Praetor
33%inclusion1 decks3 decks
28%synergy
Massacre Wurm
33%inclusion1 decks3 decks
16%synergy
Phyrexian Digester
33%inclusion1 decks3 decks
33%synergy
Sheoldred's Headcleaver
33%inclusion1 decks3 decks
33%synergy
Toxic Nim
33%inclusion1 decks3 decks
33%synergy
Septic Rats
33%inclusion1 decks3 decks
31%synergy
Phyrexian Fleshgorger
33%inclusion1 decks3 decks
33%synergy
Necropede
33%inclusion1 decks3 decks
33%synergy
Bloodgift Demon
33%inclusion1 decks3 decks
30%synergy
Blightsteel Colossus
33%inclusion1 decks3 decks
33%synergy
Dauthi Voidwalker
33%inclusion1 decks3 decks
17%synergy
Instants
Vraska's Fall
100%inclusion3 decks3 decks
96%synergy
Fell the Profane
67%inclusion2 decks3 decks
48%synergy
Imp's Mischief
67%inclusion2 decks3 decks
43%synergy
Malakir Rebirth
67%inclusion2 decks3 decks
44%synergy
Deadly Rollick
33%inclusion1 decks3 decks
10%synergy
Force of Despair
33%inclusion1 decks3 decks
26%synergy
Sheoldred's Edict
33%inclusion1 decks3 decks
19%synergy
Whisper of the Dross
33%inclusion1 decks3 decks
30%synergy
Go for the Throat
33%inclusion1 decks3 decks
10%synergy
Snuff Out
33%inclusion1 decks3 decks
21%synergy
Consuming Corruption
33%inclusion1 decks3 decks
17%synergy
Anoint with Affliction
33%inclusion1 decks3 decks
33%synergy
Howl from Beyond
33%inclusion1 decks3 decks
33%synergy
Hatred
33%inclusion1 decks3 decks
32%synergy
Defile
33%inclusion1 decks3 decks
-4%synergy
Dark Ritual
33%inclusion1 decks3 decks
-33%synergy
Doom Blade
33%inclusion1 decks3 decks
26%synergy
Hellish Rebuke
33%inclusion1 decks3 decks
32%synergy
Soul Shatter
33%inclusion1 decks3 decks
21%synergy
Withering Boon
33%inclusion1 decks3 decks
29%synergy
Infernal Grasp
33%inclusion1 decks3 decks
8%synergy
Tainted Strike
33%inclusion1 decks3 decks
30%synergy
Baleful Mastery
33%inclusion1 decks3 decks
24%synergy
Vona's Hunger
33%inclusion1 decks3 decks
29%synergy
Dismember
33%inclusion1 decks3 decks
22%synergy
Withering Torment
33%inclusion1 decks3 decks
2%synergy
Sorceries
Feed the Swarm
100%inclusion3 decks3 decks
49%synergy
Feed the Infection
67%inclusion2 decks3 decks
66%synergy
Phyresis Outbreak
67%inclusion2 decks3 decks
65%synergy
Infectious Inquiry
67%inclusion2 decks3 decks
64%synergy
Geth's Summons
67%inclusion2 decks3 decks
66%synergy
Drown in Ichor
67%inclusion2 decks3 decks
62%synergy
Vat Emergence
33%inclusion1 decks3 decks
32%synergy
Profane Tutor
33%inclusion1 decks3 decks
29%synergy
Torment of Hailfire
33%inclusion1 decks3 decks
17%synergy
Crux of Fate
33%inclusion1 decks3 decks
32%synergy
Exsanguinate
33%inclusion1 decks3 decks
9%synergy
Caress of Phyrexia
33%inclusion1 decks3 decks
33%synergy
Gix's Command
33%inclusion1 decks3 decks
31%synergy
Syphon Mind
33%inclusion1 decks3 decks
20%synergy
Insatiable Avarice
33%inclusion1 decks3 decks
21%synergy
Toxic Deluge
33%inclusion1 decks3 decks
-4%synergy
Sign in Blood
33%inclusion1 decks3 decks
-3%synergy
Damnation
33%inclusion1 decks3 decks
13%synergy
Utility Artifacts
Jet Medallion
100%inclusion3 decks3 decks
39%synergy
Lashwrithe
67%inclusion2 decks3 decks
63%synergy
Nightmare Lash
67%inclusion2 decks3 decks
64%synergy
Leyline Axe
67%inclusion2 decks3 decks
66%synergy
Sword of Truth and Justice
67%inclusion2 decks3 decks
66%synergy
Swiftfoot Boots
67%inclusion2 decks3 decks
35%synergy
Blackblade Reforged
67%inclusion2 decks3 decks
64%synergy
Sword of Light and Shadow
33%inclusion1 decks3 decks
33%synergy
Sword of Once and Future
33%inclusion1 decks3 decks
33%synergy
Sword of Fire and Ice
33%inclusion1 decks3 decks
33%synergy
Thran Power Suit
33%inclusion1 decks3 decks
33%synergy
Mithril Coat
33%inclusion1 decks3 decks
28%synergy
Bitterthorn, Nissa's Animus
33%inclusion1 decks3 decks
32%synergy
Cranial Plating
33%inclusion1 decks3 decks
30%synergy
Wishclaw Talisman
33%inclusion1 decks3 decks
27%synergy
Shadowspear
33%inclusion1 decks3 decks
30%synergy
Expedition Map
33%inclusion1 decks3 decks
21%synergy
Sword of Hearth and Home
33%inclusion1 decks3 decks
32%synergy
Bontu's Monument
33%inclusion1 decks3 decks
5%synergy
Fireshrieker
33%inclusion1 decks3 decks
31%synergy
Strata Scythe
33%inclusion1 decks3 decks
33%synergy
Sword of War and Peace
33%inclusion1 decks3 decks
33%synergy
Silver Shroud Costume
33%inclusion1 decks3 decks
32%synergy
Champion's Helm
33%inclusion1 decks3 decks
31%synergy
Sword of Forge and Frontier
33%inclusion1 decks3 decks
33%synergy
Lightning Greaves
33%inclusion1 decks3 decks
0%synergy
Commander's Plate
33%inclusion1 decks3 decks
28%synergy
Sword of Sinew and Steel
33%inclusion1 decks3 decks
33%synergy
Sword of Feast and Famine
33%inclusion1 decks3 decks
32%synergy
Sword of the Animist
33%inclusion1 decks3 decks
29%synergy
Loxodon Warhammer
33%inclusion1 decks3 decks
32%synergy
Sword of Vengeance
33%inclusion1 decks3 decks
32%synergy
Hammer of Nazahn
33%inclusion1 decks3 decks
33%synergy
Sword of Body and Mind
33%inclusion1 decks3 decks
33%synergy
The Darkness Crystal
33%inclusion1 decks3 decks
14%synergy
Enchantments
Phyrexian Arena
100%inclusion3 decks3 decks
60%synergy
Black Market Connections
67%inclusion2 decks3 decks
43%synergy
Glistening Oil
33%inclusion1 decks3 decks
33%synergy
Meathook Massacre II
33%inclusion1 decks3 decks
27%synergy
Phyresis
33%inclusion1 decks3 decks
31%synergy
Unspeakable Symbol
33%inclusion1 decks3 decks
32%synergy
Dauthi Embrace
33%inclusion1 decks3 decks
32%synergy
No Mercy
33%inclusion1 decks3 decks
26%synergy
Necrogen Communion
33%inclusion1 decks3 decks
31%synergy
Planeswalkers
Liliana of the Dark Realms
33%inclusion1 decks3 decks
19%synergy
Utility Lands
Shizo, Death's Storehouse
100%inclusion3 decks3 decks
90%synergy
Cabal Coffers
100%inclusion3 decks3 decks
45%synergy
Bojuka Bog
33%inclusion1 decks3 decks
-14%synergy
Cabal Stronghold
33%inclusion1 decks3 decks
-2%synergy
Buried Ruin
33%inclusion1 decks3 decks
28%synergy
Tyrite Sanctum
33%inclusion1 decks3 decks
32%synergy
Cathedral of War
33%inclusion1 decks3 decks
33%synergy
Inkmoth Nexus
33%inclusion1 decks3 decks
32%synergy
War Room
33%inclusion1 decks3 decks
17%synergy
Nykthos, Shrine to Nyx
33%inclusion1 decks3 decks
4%synergy
Karn's Bastion
33%inclusion1 decks3 decks
29%synergy
Urborg, Tomb of Yawgmoth
33%inclusion1 decks3 decks
-4%synergy
Rogue's Passage
33%inclusion1 decks3 decks
15%synergy
Mana Artifacts
Arcane Signet
100%inclusion3 decks3 decks
38%synergy
Sol Ring
100%inclusion3 decks3 decks
14%synergy
Glistening Sphere
67%inclusion2 decks3 decks
65%synergy
Throne of Eldraine
67%inclusion2 decks3 decks
56%synergy
The Soul Stone
50%inclusion1 decks2 decks
37%synergy
Charcoal Diamond
33%inclusion1 decks3 decks
10%synergy
Hedron Archive
33%inclusion1 decks3 decks
30%synergy
Heraldic Banner
33%inclusion1 decks3 decks
28%synergy
Fellwar Stone
33%inclusion1 decks3 decks
19%synergy
Infernal Idol
33%inclusion1 decks3 decks
33%synergy
Sceptre of Eternal Glory
33%inclusion1 decks3 decks
24%synergy
Extraplanar Lens
33%inclusion1 decks3 decks
28%synergy
Lands
Swamp
100%inclusion3 decks3 decks
5%synergy
Fell the Profane
67%inclusion2 decks3 decks
48%synergy
Malakir Rebirth
67%inclusion2 decks3 decks
44%synergy
Command Tower
33%inclusion1 decks3 decks
28%synergy
Myriad Landscape
33%inclusion1 decks3 decks
7%synergy
Mirrex
33%inclusion1 decks3 decks
33%synergy
Verdant Catacombs
33%inclusion1 decks3 decks
30%synergy
Cavern of Souls
33%inclusion1 decks3 decks
27%synergy
Marsh Flats
33%inclusion1 decks3 decks
30%synergy
Polluted Delta
33%inclusion1 decks3 decks
30%synergy
Bloodstained Mire
33%inclusion1 decks3 decks
30%synergy
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