Skithiryx, the Blight Dragon (Commander) - Expensive Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #779
4decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
Mana Artifacts
Lands
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Vraska's Fall
100%inclusion4 decks4 decks
96%synergy
Shizo, Death's Storehouse
100%inclusion4 decks4 decks
90%synergy
Phyrexian Arena
100%inclusion4 decks4 decks
60%synergy
Crypt Ghast
100%inclusion4 decks4 decks
52%synergy
Feed the Swarm
100%inclusion4 decks4 decks
49%synergy
Cabal Coffers
100%inclusion4 decks4 decks
45%synergy
Jet Medallion
100%inclusion4 decks4 decks
39%synergy
Game Changers
Bolas's Citadel
25%inclusion1 decks4 decks
-4%synergy
Creatures
Plague Stinger
75%inclusion3 decks4 decks
74%synergy
Phyrexian Obliterator
75%inclusion3 decks4 decks
64%synergy
Phyrexian Crusader
75%inclusion3 decks4 decks
74%synergy
Hand of the Praetors
75%inclusion3 decks4 decks
74%synergy
Ichor Rats
75%inclusion3 decks4 decks
72%synergy
Core Prowler
50%inclusion2 decks4 decks
49%synergy
Whispering Specter
50%inclusion2 decks4 decks
49%synergy
Magus of the Coffers
50%inclusion2 decks4 decks
43%synergy
Reaper of Sheoldred
50%inclusion2 decks4 decks
49%synergy
Plague Myr
50%inclusion2 decks4 decks
49%synergy
Flensermite
50%inclusion2 decks4 decks
49%synergy
Myr Convert
50%inclusion2 decks4 decks
49%synergy
Nirkana Revenant
50%inclusion2 decks4 decks
38%synergy
Ichorclaw Myr
50%inclusion2 decks4 decks
49%synergy
Corpse Cur
50%inclusion2 decks4 decks
50%synergy
Sheoldred, Whispering One
50%inclusion2 decks4 decks
38%synergy
Yawgmoth, Thran Physician
50%inclusion2 decks4 decks
40%synergy
Blightbelly Rat
50%inclusion2 decks4 decks
46%synergy
Flesh-Eater Imp
50%inclusion2 decks4 decks
49%synergy
Solemn Simulacrum
25%inclusion1 decks4 decks
2%synergy
Contagious Nim
25%inclusion1 decks4 decks
25%synergy
Korlash, Heir to Blackblade
25%inclusion1 decks4 decks
25%synergy
Murderous Rider
25%inclusion1 decks4 decks
18%synergy
Blackcleave Goblin
25%inclusion1 decks4 decks
25%synergy
Dread Presence
25%inclusion1 decks4 decks
10%synergy
Pestilent Syphoner
25%inclusion1 decks4 decks
24%synergy
Silent Arbiter
25%inclusion1 decks4 decks
24%synergy
Dark Confidant
25%inclusion1 decks4 decks
18%synergy
Sheoldred, the Apocalypse
25%inclusion1 decks4 decks
10%synergy
Filth
25%inclusion1 decks4 decks
23%synergy
Necroskitter
25%inclusion1 decks4 decks
22%synergy
Unstoppable Slasher
25%inclusion1 decks4 decks
19%synergy
Bilious Skulldweller
25%inclusion1 decks4 decks
24%synergy
Gix, Yawgmoth Praetor
25%inclusion1 decks4 decks
20%synergy
Massacre Wurm
25%inclusion1 decks4 decks
8%synergy
Phyrexian Digester
25%inclusion1 decks4 decks
25%synergy
Sheoldred's Headcleaver
25%inclusion1 decks4 decks
25%synergy
Toxic Nim
25%inclusion1 decks4 decks
25%synergy
Septic Rats
25%inclusion1 decks4 decks
23%synergy
K'rrik, Son of Yawgmoth
25%inclusion1 decks4 decks
6%synergy
Phyrexian Fleshgorger
25%inclusion1 decks4 decks
24%synergy
Necropede
25%inclusion1 decks4 decks
25%synergy
Bloodgift Demon
25%inclusion1 decks4 decks
22%synergy
Blightsteel Colossus
25%inclusion1 decks4 decks
24%synergy
Dauthi Voidwalker
25%inclusion1 decks4 decks
9%synergy
Instants
Imp's Mischief
75%inclusion3 decks4 decks
51%synergy
Deadly Rollick
50%inclusion2 decks4 decks
26%synergy
Fell the Profane
50%inclusion2 decks4 decks
31%synergy
Force of Despair
50%inclusion2 decks4 decks
42%synergy
Go for the Throat
50%inclusion2 decks4 decks
27%synergy
Howl from Beyond
50%inclusion2 decks4 decks
49%synergy
Defile
50%inclusion2 decks4 decks
12%synergy
Dark Ritual
50%inclusion2 decks4 decks
-17%synergy
Doom Blade
50%inclusion2 decks4 decks
42%synergy
Infernal Grasp
50%inclusion2 decks4 decks
25%synergy
Malakir Rebirth
50%inclusion2 decks4 decks
27%synergy
Hero's Downfall
25%inclusion1 decks4 decks
18%synergy
Sheoldred's Edict
25%inclusion1 decks4 decks
11%synergy
Whisper of the Dross
25%inclusion1 decks4 decks
22%synergy
Snuff Out
25%inclusion1 decks4 decks
12%synergy
Consuming Corruption
25%inclusion1 decks4 decks
9%synergy
Anoint with Affliction
25%inclusion1 decks4 decks
24%synergy
Hatred
25%inclusion1 decks4 decks
24%synergy
Hellish Rebuke
25%inclusion1 decks4 decks
23%synergy
Soul Shatter
25%inclusion1 decks4 decks
13%synergy
Withering Boon
25%inclusion1 decks4 decks
21%synergy
Unlikely Aid
25%inclusion1 decks4 decks
24%synergy
Darkness
25%inclusion1 decks4 decks
15%synergy
Tainted Strike
25%inclusion1 decks4 decks
22%synergy
Baleful Mastery
25%inclusion1 decks4 decks
16%synergy
Vona's Hunger
25%inclusion1 decks4 decks
20%synergy
Dismember
25%inclusion1 decks4 decks
14%synergy
Withering Torment
25%inclusion1 decks4 decks
-7%synergy
Sorceries
Phyresis Outbreak
75%inclusion3 decks4 decks
73%synergy
Infectious Inquiry
75%inclusion3 decks4 decks
72%synergy
Geth's Summons
75%inclusion3 decks4 decks
75%synergy
Drown in Ichor
75%inclusion3 decks4 decks
71%synergy
Feed the Infection
50%inclusion2 decks4 decks
49%synergy
Crux of Fate
50%inclusion2 decks4 decks
49%synergy
Toxic Deluge
50%inclusion2 decks4 decks
13%synergy
Sign in Blood
50%inclusion2 decks4 decks
14%synergy
Damnation
50%inclusion2 decks4 decks
29%synergy
Vat Emergence
25%inclusion1 decks4 decks
23%synergy
Profane Tutor
25%inclusion1 decks4 decks
21%synergy
Torment of Hailfire
25%inclusion1 decks4 decks
9%synergy
Bubbling Muck
25%inclusion1 decks4 decks
9%synergy
Read the Bones
25%inclusion1 decks4 decks
7%synergy
Mutilate
25%inclusion1 decks4 decks
6%synergy
Blood Money
25%inclusion1 decks4 decks
22%synergy
Night's Whisper
25%inclusion1 decks4 decks
1%synergy
Exsanguinate
25%inclusion1 decks4 decks
1%synergy
Caress of Phyrexia
25%inclusion1 decks4 decks
24%synergy
Gix's Command
25%inclusion1 decks4 decks
23%synergy
Reanimate
25%inclusion1 decks4 decks
-14%synergy
In Garruk's Wake
25%inclusion1 decks4 decks
21%synergy
Syphon Mind
25%inclusion1 decks4 decks
12%synergy
Insatiable Avarice
25%inclusion1 decks4 decks
13%synergy
Overwhelming Forces
25%inclusion1 decks4 decks
24%synergy
Utility Artifacts
Lashwrithe
75%inclusion3 decks4 decks
71%synergy
Nightmare Lash
75%inclusion3 decks4 decks
73%synergy
Leyline Axe
75%inclusion3 decks4 decks
74%synergy
Sword of Truth and Justice
75%inclusion3 decks4 decks
74%synergy
Swiftfoot Boots
75%inclusion3 decks4 decks
43%synergy
Blackblade Reforged
75%inclusion3 decks4 decks
72%synergy
Fireshrieker
50%inclusion2 decks4 decks
48%synergy
Champion's Helm
50%inclusion2 decks4 decks
48%synergy
Lightning Greaves
50%inclusion2 decks4 decks
16%synergy
Commander's Plate
50%inclusion2 decks4 decks
44%synergy
Sword of Feast and Famine
50%inclusion2 decks4 decks
48%synergy
Hammer of Nazahn
50%inclusion2 decks4 decks
49%synergy
The Darkness Crystal
50%inclusion2 decks4 decks
30%synergy
Sword of Light and Shadow
25%inclusion1 decks4 decks
24%synergy
Sword of Once and Future
25%inclusion1 decks4 decks
25%synergy
Sword of Fire and Ice
25%inclusion1 decks4 decks
25%synergy
Thran Power Suit
25%inclusion1 decks4 decks
25%synergy
Mithril Coat
25%inclusion1 decks4 decks
19%synergy
Bitterthorn, Nissa's Animus
25%inclusion1 decks4 decks
24%synergy
Cranial Plating
25%inclusion1 decks4 decks
21%synergy
Wishclaw Talisman
25%inclusion1 decks4 decks
18%synergy
Shadowspear
25%inclusion1 decks4 decks
21%synergy
Expedition Map
25%inclusion1 decks4 decks
13%synergy
Sword of Hearth and Home
25%inclusion1 decks4 decks
24%synergy
Bontu's Monument
25%inclusion1 decks4 decks
-3%synergy
Whispersilk Cloak
25%inclusion1 decks4 decks
19%synergy
Strata Scythe
25%inclusion1 decks4 decks
24%synergy
Sword of War and Peace
25%inclusion1 decks4 decks
25%synergy
Silver Shroud Costume
25%inclusion1 decks4 decks
24%synergy
Sword of Forge and Frontier
25%inclusion1 decks4 decks
24%synergy
Sword of Sinew and Steel
25%inclusion1 decks4 decks
25%synergy
Sword of the Animist
25%inclusion1 decks4 decks
21%synergy
Loxodon Warhammer
25%inclusion1 decks4 decks
24%synergy
Sword of Vengeance
25%inclusion1 decks4 decks
24%synergy
Hero's Blade
25%inclusion1 decks4 decks
25%synergy
Sword of Body and Mind
25%inclusion1 decks4 decks
25%synergy
Enchantments
Unspeakable Symbol
50%inclusion2 decks4 decks
49%synergy
No Mercy
50%inclusion2 decks4 decks
43%synergy
Black Market Connections
50%inclusion2 decks4 decks
27%synergy
Super State
33%inclusion1 decks3 decks
33%synergy
Black Market
25%inclusion1 decks4 decks
4%synergy
Glistening Oil
25%inclusion1 decks4 decks
24%synergy
Shade's Form
25%inclusion1 decks4 decks
24%synergy
Meathook Massacre II
25%inclusion1 decks4 decks
18%synergy
Phyresis
25%inclusion1 decks4 decks
23%synergy
Kaya's Ghostform
25%inclusion1 decks4 decks
15%synergy
Dauthi Embrace
25%inclusion1 decks4 decks
23%synergy
Necrogen Communion
25%inclusion1 decks4 decks
23%synergy
Planeswalkers
Liliana of the Dark Realms
25%inclusion1 decks4 decks
11%synergy
Utility Lands
Cabal Stronghold
50%inclusion2 decks4 decks
15%synergy
Cathedral of War
50%inclusion2 decks4 decks
50%synergy
Urborg, Tomb of Yawgmoth
50%inclusion2 decks4 decks
12%synergy
Bojuka Bog
25%inclusion1 decks4 decks
-22%synergy
Buried Ruin
25%inclusion1 decks4 decks
20%synergy
Tyrite Sanctum
25%inclusion1 decks4 decks
24%synergy
Inkmoth Nexus
25%inclusion1 decks4 decks
24%synergy
War Room
25%inclusion1 decks4 decks
8%synergy
Nykthos, Shrine to Nyx
25%inclusion1 decks4 decks
-5%synergy
Karn's Bastion
25%inclusion1 decks4 decks
21%synergy
Rogue's Passage
25%inclusion1 decks4 decks
6%synergy
Mana Artifacts
Sol Ring
100%inclusion4 decks4 decks
14%synergy
Arcane Signet
75%inclusion3 decks4 decks
13%synergy
Glistening Sphere
50%inclusion2 decks4 decks
49%synergy
Throne of Eldraine
50%inclusion2 decks4 decks
39%synergy
The Soul Stone
33%inclusion1 decks3 decks
20%synergy
Charcoal Diamond
25%inclusion1 decks4 decks
2%synergy
Hedron Archive
25%inclusion1 decks4 decks
21%synergy
Heraldic Banner
25%inclusion1 decks4 decks
19%synergy
Fellwar Stone
25%inclusion1 decks4 decks
10%synergy
Infernal Idol
25%inclusion1 decks4 decks
24%synergy
Sceptre of Eternal Glory
25%inclusion1 decks4 decks
16%synergy
Extraplanar Lens
25%inclusion1 decks4 decks
20%synergy
Lands
Swamp
100%inclusion4 decks4 decks
5%synergy
Fell the Profane
50%inclusion2 decks4 decks
31%synergy
Malakir Rebirth
50%inclusion2 decks4 decks
27%synergy
Command Tower
25%inclusion1 decks4 decks
19%synergy
Myriad Landscape
25%inclusion1 decks4 decks
-1%synergy
Mirrex
25%inclusion1 decks4 decks
24%synergy
Verdant Catacombs
25%inclusion1 decks4 decks
22%synergy
Cavern of Souls
25%inclusion1 decks4 decks
18%synergy
Marsh Flats
25%inclusion1 decks4 decks
22%synergy
Polluted Delta
25%inclusion1 decks4 decks
22%synergy
Bloodstained Mire
25%inclusion1 decks4 decks
21%synergy
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