Skithiryx, the Blight Dragon (Commander) - Expensive Core Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #781
4decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Lands
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Shizo, Death's Storehouse
100%inclusion4 decks4 decks
90%synergy
Bojuka Bog
100%inclusion4 decks4 decks
53%synergy
Crypt Ghast
100%inclusion4 decks4 decks
52%synergy
Cabal Coffers
100%inclusion4 decks4 decks
45%synergy
Jet Medallion
100%inclusion4 decks4 decks
39%synergy
Creatures
Phyrexian Obliterator
75%inclusion3 decks4 decks
64%synergy
Plague Stinger
50%inclusion2 decks4 decks
49%synergy
Core Prowler
50%inclusion2 decks4 decks
49%synergy
Dread Presence
50%inclusion2 decks4 decks
35%synergy
Whispering Specter
50%inclusion2 decks4 decks
49%synergy
Plague Myr
50%inclusion2 decks4 decks
49%synergy
Flensermite
50%inclusion2 decks4 decks
49%synergy
Bilious Skulldweller
50%inclusion2 decks4 decks
49%synergy
Phyrexian Crusader
50%inclusion2 decks4 decks
49%synergy
Yawgmoth, Thran Physician
50%inclusion2 decks4 decks
40%synergy
Blightbelly Rat
50%inclusion2 decks4 decks
46%synergy
K'rrik, Son of Yawgmoth
50%inclusion2 decks4 decks
31%synergy
Hand of the Praetors
50%inclusion2 decks4 decks
49%synergy
Solemn Simulacrum
25%inclusion1 decks4 decks
2%synergy
Ozox, the Clattering King
25%inclusion1 decks4 decks
24%synergy
Korlash, Heir to Blackblade
25%inclusion1 decks4 decks
25%synergy
Murderous Rider
25%inclusion1 decks4 decks
18%synergy
Maha, Its Feathers Night
25%inclusion1 decks4 decks
20%synergy
Vector Asp
25%inclusion1 decks4 decks
25%synergy
Grim Roustabout
25%inclusion1 decks4 decks
25%synergy
Pestilent Syphoner
25%inclusion1 decks4 decks
24%synergy
Silent Arbiter
25%inclusion1 decks4 decks
24%synergy
Dark Confidant
25%inclusion1 decks4 decks
18%synergy
Magus of the Coffers
25%inclusion1 decks4 decks
18%synergy
Reaper of Sheoldred
25%inclusion1 decks4 decks
24%synergy
Skeleton Crew
25%inclusion1 decks4 decks
24%synergy
Sheoldred, the Apocalypse
25%inclusion1 decks4 decks
10%synergy
Gray Merchant of Asphodel
25%inclusion1 decks4 decks
-27%synergy
Restless Dead
25%inclusion1 decks4 decks
25%synergy
Persistent Specimen
25%inclusion1 decks4 decks
23%synergy
Kjeldoran Dead
25%inclusion1 decks4 decks
25%synergy
Banehound
25%inclusion1 decks4 decks
24%synergy
Sifter of Skulls
25%inclusion1 decks4 decks
21%synergy
Gisa, the Hellraiser
25%inclusion1 decks4 decks
21%synergy
Myr Convert
25%inclusion1 decks4 decks
24%synergy
Nirkana Revenant
25%inclusion1 decks4 decks
14%synergy
Augur of Skulls
25%inclusion1 decks4 decks
25%synergy
Boggart Trawler
25%inclusion1 decks4 decks
16%synergy
Unworthy Dead
25%inclusion1 decks4 decks
25%synergy
Tinybones, the Pickpocket
25%inclusion1 decks4 decks
20%synergy
Ichorclaw Myr
25%inclusion1 decks4 decks
24%synergy
Skeleton Scavengers
25%inclusion1 decks4 decks
25%synergy
Cinderbones
25%inclusion1 decks4 decks
25%synergy
Corpse Cur
25%inclusion1 decks4 decks
25%synergy
Massacre Wurm
25%inclusion1 decks4 decks
8%synergy
Death Baron
25%inclusion1 decks4 decks
19%synergy
Tenacious Dead
25%inclusion1 decks4 decks
24%synergy
Reassembling Skeleton
25%inclusion1 decks4 decks
8%synergy
Asphodel Wanderer
25%inclusion1 decks4 decks
25%synergy
Pitiless Plunderer
25%inclusion1 decks4 decks
6%synergy
Instants
Vraska's Fall
75%inclusion3 decks4 decks
71%synergy
Defile
75%inclusion3 decks4 decks
38%synergy
Dark Ritual
75%inclusion3 decks4 decks
8%synergy
Fell the Profane
50%inclusion2 decks4 decks
31%synergy
Whisper of the Dross
50%inclusion2 decks4 decks
47%synergy
Grim Affliction
50%inclusion2 decks4 decks
48%synergy
Tainted Strike
50%inclusion2 decks4 decks
47%synergy
Malakir Rebirth
50%inclusion2 decks4 decks
27%synergy
Withering Torment
50%inclusion2 decks4 decks
18%synergy
Deadly Rollick
25%inclusion1 decks4 decks
1%synergy
Bone Harvest
25%inclusion1 decks4 decks
25%synergy
Sheoldred's Edict
25%inclusion1 decks4 decks
11%synergy
Imp's Mischief
25%inclusion1 decks4 decks
1%synergy
Village Rites
25%inclusion1 decks4 decks
0%synergy
Consuming Corruption
25%inclusion1 decks4 decks
9%synergy
Anoint with Affliction
25%inclusion1 decks4 decks
24%synergy
Howl from Beyond
25%inclusion1 decks4 decks
24%synergy
Hatred
25%inclusion1 decks4 decks
24%synergy
Deadly Dispute
25%inclusion1 decks4 decks
0%synergy
Culling the Weak
25%inclusion1 decks4 decks
10%synergy
Armor of Shadows
25%inclusion1 decks4 decks
23%synergy
Virulent Wound
25%inclusion1 decks4 decks
25%synergy
Withering Boon
25%inclusion1 decks4 decks
21%synergy
Infernal Grasp
25%inclusion1 decks4 decks
0%synergy
Baleful Mastery
25%inclusion1 decks4 decks
16%synergy
Corrupted Conviction
25%inclusion1 decks4 decks
13%synergy
Tragic Slip
25%inclusion1 decks4 decks
5%synergy
Sorceries
Drown in Ichor
75%inclusion3 decks4 decks
71%synergy
Vat Emergence
50%inclusion2 decks4 decks
48%synergy
Phyresis Outbreak
50%inclusion2 decks4 decks
48%synergy
Crux of Fate
50%inclusion2 decks4 decks
49%synergy
Feed the Swarm
50%inclusion2 decks4 decks
-1%synergy
Infectious Inquiry
50%inclusion2 decks4 decks
47%synergy
Exsanguinate
50%inclusion2 decks4 decks
25%synergy
Toxic Deluge
50%inclusion2 decks4 decks
13%synergy
Bone Splinters
25%inclusion1 decks4 decks
23%synergy
Spread the Sickness
25%inclusion1 decks4 decks
24%synergy
Profane Tutor
25%inclusion1 decks4 decks
21%synergy
Bubbling Muck
25%inclusion1 decks4 decks
9%synergy
Feed the Infection
25%inclusion1 decks4 decks
24%synergy
Agadeem's Awakening
25%inclusion1 decks4 decks
18%synergy
Mutilate
25%inclusion1 decks4 decks
7%synergy
Night's Whisper
25%inclusion1 decks4 decks
1%synergy
Caress of Phyrexia
25%inclusion1 decks4 decks
24%synergy
Ambition's Cost
25%inclusion1 decks4 decks
22%synergy
Reanimate
25%inclusion1 decks4 decks
-14%synergy
In Garruk's Wake
25%inclusion1 decks4 decks
21%synergy
Syphon Mind
25%inclusion1 decks4 decks
12%synergy
Insatiable Avarice
25%inclusion1 decks4 decks
13%synergy
Geth's Summons
25%inclusion1 decks4 decks
25%synergy
Sign in Blood
25%inclusion1 decks4 decks
-11%synergy
Final Vengeance
25%inclusion1 decks4 decks
23%synergy
Rise of the Dark Realms
25%inclusion1 decks4 decks
12%synergy
Blood for Bones
25%inclusion1 decks4 decks
24%synergy
Utility Artifacts
Lashwrithe
75%inclusion3 decks4 decks
71%synergy
Sword of Truth and Justice
75%inclusion3 decks4 decks
74%synergy
Swiftfoot Boots
75%inclusion3 decks4 decks
43%synergy
Nightmare Lash
50%inclusion2 decks4 decks
48%synergy
Contagion Clasp
50%inclusion2 decks4 decks
48%synergy
Contagion Engine
50%inclusion2 decks4 decks
48%synergy
Leyline Axe
50%inclusion2 decks4 decks
49%synergy
Shadowspear
50%inclusion2 decks4 decks
46%synergy
Fireshrieker
50%inclusion2 decks4 decks
48%synergy
Commander's Plate
50%inclusion2 decks4 decks
44%synergy
Blackblade Reforged
50%inclusion2 decks4 decks
47%synergy
Sword of Light and Shadow
25%inclusion1 decks4 decks
24%synergy
Sword of Once and Future
25%inclusion1 decks4 decks
25%synergy
Sword of Fire and Ice
25%inclusion1 decks4 decks
25%synergy
Skeleton Key
25%inclusion1 decks4 decks
24%synergy
Thran Power Suit
25%inclusion1 decks4 decks
25%synergy
Mithril Coat
25%inclusion1 decks4 decks
19%synergy
Bitterthorn, Nissa's Animus
25%inclusion1 decks4 decks
24%synergy
Skullclamp
25%inclusion1 decks4 decks
4%synergy
Cranial Plating
25%inclusion1 decks4 decks
22%synergy
Vanquisher's Banner
25%inclusion1 decks4 decks
21%synergy
Phyrexian Altar
25%inclusion1 decks4 decks
12%synergy
Expedition Map
25%inclusion1 decks4 decks
13%synergy
Sword of Hearth and Home
25%inclusion1 decks4 decks
24%synergy
Bontu's Monument
25%inclusion1 decks4 decks
-3%synergy
Whispersilk Cloak
25%inclusion1 decks4 decks
19%synergy
Door of Destinies
25%inclusion1 decks4 decks
23%synergy
Strata Scythe
25%inclusion1 decks4 decks
24%synergy
Sword of War and Peace
25%inclusion1 decks4 decks
25%synergy
Silver Shroud Costume
25%inclusion1 decks4 decks
24%synergy
Pact Weapon
25%inclusion1 decks4 decks
23%synergy
Champion's Helm
25%inclusion1 decks4 decks
23%synergy
Sword of Forge and Frontier
25%inclusion1 decks4 decks
24%synergy
Lightning Greaves
25%inclusion1 decks4 decks
-9%synergy
Sword of Sinew and Steel
25%inclusion1 decks4 decks
25%synergy
Sword of Feast and Famine
25%inclusion1 decks4 decks
23%synergy
Brotherhood Regalia
25%inclusion1 decks4 decks
23%synergy
Sword of the Animist
25%inclusion1 decks4 decks
21%synergy
Loxodon Warhammer
25%inclusion1 decks4 decks
24%synergy
Sword of Vengeance
25%inclusion1 decks4 decks
24%synergy
Hammer of Nazahn
25%inclusion1 decks4 decks
24%synergy
Sword of Body and Mind
25%inclusion1 decks4 decks
25%synergy
Enchantments
Phyrexian Arena
75%inclusion3 decks4 decks
35%synergy
Open the Graves
25%inclusion1 decks4 decks
22%synergy
Gift of Doom
25%inclusion1 decks4 decks
24%synergy
Glistening Oil
25%inclusion1 decks4 decks
24%synergy
Grave Pact
25%inclusion1 decks4 decks
6%synergy
Corpses of the Lost
25%inclusion1 decks4 decks
24%synergy
Dictate of Erebos
25%inclusion1 decks4 decks
14%synergy
Phyresis
25%inclusion1 decks4 decks
23%synergy
Unspeakable Symbol
25%inclusion1 decks4 decks
24%synergy
Kaya's Ghostform
25%inclusion1 decks4 decks
15%synergy
Dauthi Embrace
25%inclusion1 decks4 decks
23%synergy
Black Market Connections
25%inclusion1 decks4 decks
2%synergy
Bad Moon
25%inclusion1 decks4 decks
22%synergy
Necrogen Communion
25%inclusion1 decks4 decks
23%synergy
Planeswalkers
Vraska, Betrayal's Sting
75%inclusion3 decks4 decks
72%synergy
Liliana of the Dark Realms
50%inclusion2 decks4 decks
36%synergy
Utility Lands
Cabal Stronghold
75%inclusion3 decks4 decks
40%synergy
Phyrexian Tower
50%inclusion2 decks4 decks
26%synergy
Cathedral of War
50%inclusion2 decks4 decks
50%synergy
Inkmoth Nexus
50%inclusion2 decks4 decks
49%synergy
Nykthos, Shrine to Nyx
50%inclusion2 decks4 decks
20%synergy
Karn's Bastion
50%inclusion2 decks4 decks
46%synergy
Urborg, Tomb of Yawgmoth
50%inclusion2 decks4 decks
12%synergy
Rogue's Passage
50%inclusion2 decks4 decks
31%synergy
Witch's Clinic
25%inclusion1 decks4 decks
24%synergy
Buried Ruin
25%inclusion1 decks4 decks
20%synergy
Tyrite Sanctum
25%inclusion1 decks4 decks
24%synergy
Crypt of Agadeem
25%inclusion1 decks4 decks
14%synergy
Crystal Vein
25%inclusion1 decks4 decks
22%synergy
Witch's Cottage
25%inclusion1 decks4 decks
0%synergy
Command Beacon
25%inclusion1 decks4 decks
17%synergy
Tomb Fortress
25%inclusion1 decks4 decks
21%synergy
Muraganda Raceway
25%inclusion1 decks4 decks
23%synergy
Everglades
25%inclusion1 decks4 decks
24%synergy
Spawning Pool
25%inclusion1 decks4 decks
25%synergy
Hidden Necropolis
25%inclusion1 decks4 decks
23%synergy
Mana Artifacts
Sol Ring
100%inclusion4 decks4 decks
14%synergy
Arcane Signet
75%inclusion3 decks4 decks
13%synergy
Staff of Compleation
50%inclusion2 decks4 decks
48%synergy
Charcoal Diamond
50%inclusion2 decks4 decks
27%synergy
The Soul Stone
50%inclusion1 decks2 decks
37%synergy
Glistening Sphere
25%inclusion1 decks4 decks
24%synergy
Hedron Archive
25%inclusion1 decks4 decks
21%synergy
Heraldic Banner
25%inclusion1 decks4 decks
19%synergy
Fellwar Stone
25%inclusion1 decks4 decks
10%synergy
Infernal Idol
25%inclusion1 decks4 decks
24%synergy
Lands
Swamp
100%inclusion4 decks4 decks
5%synergy
Fell the Profane
50%inclusion2 decks4 decks
31%synergy
Myriad Landscape
50%inclusion2 decks4 decks
24%synergy
Mirrex
50%inclusion2 decks4 decks
49%synergy
Malakir Rebirth
50%inclusion2 decks4 decks
27%synergy
Agadeem's Awakening
25%inclusion1 decks4 decks
18%synergy
Verdant Catacombs
25%inclusion1 decks4 decks
22%synergy
Boggart Trawler
25%inclusion1 decks4 decks
16%synergy
Cavern of Souls
25%inclusion1 decks4 decks
18%synergy
Marsh Flats
25%inclusion1 decks4 decks
22%synergy
Polluted Delta
25%inclusion1 decks4 decks
22%synergy
Bloodstained Mire
25%inclusion1 decks4 decks
21%synergy
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