Skithiryx, the Blight Dragon (Commander) - Expensive Upgraded Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #781
6decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Sword of Truth and Justice
83%inclusion5 decks6 decks
83%synergy
Infectious Inquiry
83%inclusion5 decks6 decks
80%synergy
Commander's Plate
83%inclusion5 decks6 decks
78%synergy
Shizo, Death's Storehouse
83%inclusion5 decks6 decks
73%synergy
War Room
83%inclusion5 decks6 decks
67%synergy
Hammer of Nazahn
67%inclusion4 decks6 decks
66%synergy
Sword of Vengeance
67%inclusion4 decks6 decks
66%synergy
Inkmoth Nexus
67%inclusion4 decks6 decks
66%synergy
Astarion's Thirst
67%inclusion4 decks6 decks
65%synergy
Champion's Helm
67%inclusion4 decks6 decks
65%synergy
Top Cards
Dark Ritual
83%inclusion5 decks6 decks
17%synergy
Crypt Ghast
83%inclusion5 decks6 decks
35%synergy
Jet Medallion
83%inclusion5 decks6 decks
22%synergy
Shadowspear
67%inclusion4 decks6 decks
63%synergy
Liliana of the Dark Realms
67%inclusion4 decks6 decks
53%synergy
Tainted Strike
67%inclusion4 decks6 decks
64%synergy
Toxic Deluge
67%inclusion4 decks6 decks
30%synergy
Phyrexian Arena
67%inclusion4 decks6 decks
27%synergy
Vraska's Fall
67%inclusion4 decks6 decks
63%synergy
Game Changers
Demonic Tutor
67%inclusion4 decks6 decks
39%synergy
Vampiric Tutor
50%inclusion3 decks6 decks
29%synergy
Imperial Seal
33%inclusion2 decks6 decks
26%synergy
Ancient Tomb
33%inclusion2 decks6 decks
22%synergy
Tergrid, God of Fright
17%inclusion1 decks6 decks
9%synergy
Necropotence
17%inclusion1 decks6 decks
2%synergy
Mishra's Workshop
17%inclusion1 decks6 decks
16%synergy
Creatures
Plague Myr
50%inclusion3 decks6 decks
49%synergy
Phyrexian Crusader
50%inclusion3 decks6 decks
49%synergy
K'rrik, Son of Yawgmoth
50%inclusion3 decks6 decks
31%synergy
Dauthi Voidwalker
50%inclusion3 decks6 decks
34%synergy
Plague Stinger
33%inclusion2 decks6 decks
32%synergy
Sheoldred, the Apocalypse
33%inclusion2 decks6 decks
19%synergy
Bloodgift Demon
33%inclusion2 decks6 decks
30%synergy
Leaden Myr
33%inclusion2 decks6 decks
27%synergy
Elegy Acolyte
20%inclusion1 decks5 decks
17%synergy
Solemn Simulacrum
17%inclusion1 decks6 decks
-6%synergy
Dread
17%inclusion1 decks6 decks
16%synergy
Tree of Perdition
17%inclusion1 decks6 decks
15%synergy
Maha, Its Feathers Night
17%inclusion1 decks6 decks
12%synergy
Rune-Scarred Demon
17%inclusion1 decks6 decks
12%synergy
Dread Presence
17%inclusion1 decks6 decks
2%synergy
Whispering Specter
17%inclusion1 decks6 decks
16%synergy
Silent Arbiter
17%inclusion1 decks6 decks
15%synergy
Erebos, God of the Dead
17%inclusion1 decks6 decks
12%synergy
Scrawling Crawler
17%inclusion1 decks6 decks
13%synergy
Magus of the Coffers
17%inclusion1 decks6 decks
10%synergy
Plaguecrafter
17%inclusion1 decks6 decks
-3%synergy
Sidisi, Undead Vizier
17%inclusion1 decks6 decks
13%synergy
Blackbloom Rogue
17%inclusion1 decks6 decks
16%synergy
Gray Merchant of Asphodel
17%inclusion1 decks6 decks
-35%synergy
Filth
17%inclusion1 decks6 decks
14%synergy
Phyrexian Obliterator
17%inclusion1 decks6 decks
6%synergy
Bloodletter of Aclazotz
17%inclusion1 decks6 decks
6%synergy
Flensermite
17%inclusion1 decks6 decks
16%synergy
Brass Squire
17%inclusion1 decks6 decks
16%synergy
Mikaeus, the Unhallowed
17%inclusion1 decks6 decks
9%synergy
Varragoth, Bloodsky Sire
17%inclusion1 decks6 decks
12%synergy
Nirkana Revenant
17%inclusion1 decks6 decks
5%synergy
Burnished Hart
17%inclusion1 decks6 decks
9%synergy
Sheoldred, Whispering One
17%inclusion1 decks6 decks
5%synergy
Gix, Yawgmoth Praetor
17%inclusion1 decks6 decks
12%synergy
Xiahou Dun, the One-Eyed
17%inclusion1 decks6 decks
16%synergy
Callous Bloodmage
17%inclusion1 decks6 decks
16%synergy
Sheoldred
17%inclusion1 decks6 decks
10%synergy
Kiku, Night's Flower
17%inclusion1 decks6 decks
16%synergy
Reassembling Skeleton
17%inclusion1 decks6 decks
0%synergy
Royal Assassin
17%inclusion1 decks6 decks
14%synergy
Yawgmoth, Thran Physician
17%inclusion1 decks6 decks
7%synergy
Sheoldred's Headcleaver
17%inclusion1 decks6 decks
16%synergy
Flesh-Eater Imp
17%inclusion1 decks6 decks
16%synergy
Qarsi Revenant
17%inclusion1 decks6 decks
12%synergy
Blood Pet
17%inclusion1 decks6 decks
9%synergy
Hand of the Praetors
17%inclusion1 decks6 decks
16%synergy
Ichor Rats
17%inclusion1 decks6 decks
14%synergy
Bloodthirsty Conqueror
17%inclusion1 decks6 decks
8%synergy
Boggart Trawler
17%inclusion1 decks6 decks
8%synergy
Instants
Archenemy's Charm
60%inclusion3 decks5 decks
51%synergy
Deadly Rollick
50%inclusion3 decks6 decks
26%synergy
Imp's Mischief
50%inclusion3 decks6 decks
26%synergy
Hatred
50%inclusion3 decks6 decks
49%synergy
Withering Torment
50%inclusion3 decks6 decks
18%synergy
Hagra Mauling
33%inclusion2 decks6 decks
29%synergy
Fell the Profane
33%inclusion2 decks6 decks
15%synergy
Snuff Out
33%inclusion2 decks6 decks
20%synergy
Howl from Beyond
33%inclusion2 decks6 decks
33%synergy
Withering Boon
33%inclusion2 decks6 decks
29%synergy
Malakir Rebirth
33%inclusion2 decks6 decks
11%synergy
Rain of Filth
33%inclusion2 decks6 decks
31%synergy
Baleful Mastery
33%inclusion2 decks6 decks
24%synergy
Cabal Ritual
33%inclusion2 decks6 decks
15%synergy
Sacrifice
17%inclusion1 decks6 decks
12%synergy
Force of Despair
17%inclusion1 decks6 decks
9%synergy
Stinging Study
17%inclusion1 decks6 decks
14%synergy
Cut Down
17%inclusion1 decks6 decks
13%synergy
Go for the Throat
17%inclusion1 decks6 decks
-7%synergy
Not Dead After All
17%inclusion1 decks6 decks
5%synergy
Undying Evil
17%inclusion1 decks6 decks
13%synergy
Rouse
17%inclusion1 decks6 decks
17%synergy
Defile
17%inclusion1 decks6 decks
-21%synergy
Ulcerate
17%inclusion1 decks6 decks
16%synergy
Poison the Cup
17%inclusion1 decks6 decks
16%synergy
Culling the Weak
17%inclusion1 decks6 decks
1%synergy
Supernatural Stamina
17%inclusion1 decks6 decks
9%synergy
Rush of Vitality
17%inclusion1 decks6 decks
16%synergy
Bitter Triumph
17%inclusion1 decks6 decks
7%synergy
Undying Malice
17%inclusion1 decks6 decks
7%synergy
Darkness
17%inclusion1 decks6 decks
7%synergy
Murder
17%inclusion1 decks6 decks
6%synergy
Infernal Grasp
17%inclusion1 decks6 decks
-9%synergy
Shallow Grave
17%inclusion1 decks6 decks
16%synergy
Cast Down
17%inclusion1 decks6 decks
15%synergy
Dismember
17%inclusion1 decks6 decks
6%synergy
Sorceries
Crux of Fate
50%inclusion3 decks6 decks
49%synergy
Praetor's Grasp
50%inclusion3 decks6 decks
46%synergy
Night's Whisper
50%inclusion3 decks6 decks
26%synergy
Reanimate
50%inclusion3 decks6 decks
11%synergy
Sign in Blood
50%inclusion3 decks6 decks
14%synergy
Grim Tutor
50%inclusion3 decks6 decks
38%synergy
Bubbling Muck
33%inclusion2 decks6 decks
18%synergy
Phyresis Outbreak
33%inclusion2 decks6 decks
32%synergy
Agadeem's Awakening
33%inclusion2 decks6 decks
26%synergy
Feed the Swarm
33%inclusion2 decks6 decks
-18%synergy
Read the Bones
33%inclusion2 decks6 decks
16%synergy
Insatiable Avarice
33%inclusion2 decks6 decks
21%synergy
Zero Point Ballad
20%inclusion1 decks5 decks
18%synergy
Risky Research
20%inclusion1 decks5 decks
19%synergy
Black Sun's Zenith
17%inclusion1 decks6 decks
11%synergy
Vat Emergence
17%inclusion1 decks6 decks
15%synergy
Mandate of Abaddon
17%inclusion1 decks6 decks
15%synergy
Peer into the Abyss
17%inclusion1 decks6 decks
6%synergy
Yawgmoth's Will
17%inclusion1 decks6 decks
13%synergy
Blood on the Snow
17%inclusion1 decks6 decks
16%synergy
Blasphemous Edict
17%inclusion1 decks6 decks
0%synergy
Scheming Symmetry
17%inclusion1 decks6 decks
12%synergy
Fell
17%inclusion1 decks6 decks
13%synergy
Gix's Command
17%inclusion1 decks6 decks
15%synergy
Final Parting
17%inclusion1 decks6 decks
12%synergy
Diresight
17%inclusion1 decks6 decks
13%synergy
Syphon Mind
17%inclusion1 decks6 decks
4%synergy
Geth's Summons
17%inclusion1 decks6 decks
16%synergy
Beseech the Mirror
17%inclusion1 decks6 decks
10%synergy
Chain of Smog
17%inclusion1 decks6 decks
12%synergy
Breach the Multiverse
17%inclusion1 decks6 decks
10%synergy
Nuclear Fallout
17%inclusion1 decks6 decks
15%synergy
Torment of Hailfire
17%inclusion1 decks6 decks
1%synergy
Zof Consumption
17%inclusion1 decks6 decks
16%synergy
Utility Artifacts
Swiftfoot Boots
50%inclusion3 decks6 decks
18%synergy
Lightning Greaves
50%inclusion3 decks6 decks
16%synergy
Blackblade Reforged
50%inclusion3 decks6 decks
47%synergy
Doc Ock's Tentacles
50%inclusion1 decks2 decks
50%synergy
Lashwrithe
33%inclusion2 decks6 decks
29%synergy
Sensei's Divining Top
33%inclusion2 decks6 decks
25%synergy
Manifold Key
33%inclusion2 decks6 decks
32%synergy
Mithril Coat
33%inclusion2 decks6 decks
28%synergy
Leyline Axe
33%inclusion2 decks6 decks
32%synergy
Skullclamp
33%inclusion2 decks6 decks
12%synergy
Cranial Plating
33%inclusion2 decks6 decks
30%synergy
Expedition Map
33%inclusion2 decks6 decks
21%synergy
Pact Weapon
33%inclusion2 decks6 decks
31%synergy
Brotherhood Regalia
33%inclusion2 decks6 decks
31%synergy
The Darkness Crystal
20%inclusion1 decks5 decks
0%synergy
Buster Sword
20%inclusion1 decks5 decks
19%synergy
Dark Knight's Greatsword
20%inclusion1 decks5 decks
20%synergy
Genji Glove
20%inclusion1 decks5 decks
19%synergy
Nettlecyst
17%inclusion1 decks6 decks
16%synergy
Sword of Once and Future
17%inclusion1 decks6 decks
16%synergy
Pip-Boy 3000
17%inclusion1 decks6 decks
16%synergy
Defense Grid
17%inclusion1 decks6 decks
14%synergy
Sword of Fire and Ice
17%inclusion1 decks6 decks
16%synergy
Thran Power Suit
17%inclusion1 decks6 decks
16%synergy
Heirloom Epic
17%inclusion1 decks6 decks
17%synergy
Strength-Testing Hammer
17%inclusion1 decks6 decks
17%synergy
Ashnod's Altar
17%inclusion1 decks6 decks
-3%synergy
Throne of Geth
17%inclusion1 decks6 decks
16%synergy
Trailblazer's Boots
17%inclusion1 decks6 decks
14%synergy
Lavaspur Boots
17%inclusion1 decks6 decks
15%synergy
Mind's Eye
17%inclusion1 decks6 decks
16%synergy
Kaldra Compleat
17%inclusion1 decks6 decks
16%synergy
Haunted Cloak
17%inclusion1 decks6 decks
16%synergy
Bloodforged Battle-Axe
17%inclusion1 decks6 decks
16%synergy
Wishclaw Talisman
17%inclusion1 decks6 decks
10%synergy
Conqueror's Flail
17%inclusion1 decks6 decks
16%synergy
Excalibur, Sword of Eden
17%inclusion1 decks6 decks
16%synergy
Fireshrieker
17%inclusion1 decks6 decks
15%synergy
Inquisitor's Flail
17%inclusion1 decks6 decks
16%synergy
Sword of Wealth and Power
17%inclusion1 decks6 decks
16%synergy
Silver Shroud Costume
17%inclusion1 decks6 decks
15%synergy
Grafted Wargear
17%inclusion1 decks6 decks
16%synergy
Sword of Forge and Frontier
17%inclusion1 decks6 decks
16%synergy
Sword of Sinew and Steel
17%inclusion1 decks6 decks
16%synergy
Sword of Feast and Famine
17%inclusion1 decks6 decks
15%synergy
Dowsing Dagger
17%inclusion1 decks6 decks
16%synergy
Helm of Awakening
17%inclusion1 decks6 decks
15%synergy
Sword of Body and Mind
17%inclusion1 decks6 decks
16%synergy
Wayfarer's Bauble
17%inclusion1 decks6 decks
1%synergy
Nightmare Lash
17%inclusion1 decks6 decks
14%synergy
Enchantments
Unspeakable Symbol
50%inclusion3 decks6 decks
49%synergy
Black Market Connections
50%inclusion3 decks6 decks
26%synergy
Kaya's Ghostform
33%inclusion2 decks6 decks
23%synergy
Animate Dead
33%inclusion2 decks6 decks
16%synergy
The Meathook Massacre
17%inclusion1 decks6 decks
-1%synergy
Dance of the Dead
17%inclusion1 decks6 decks
13%synergy
Vow of Torment
17%inclusion1 decks6 decks
16%synergy
Phyrexian Reclamation
17%inclusion1 decks6 decks
7%synergy
Necromancy
17%inclusion1 decks6 decks
11%synergy
Corpses of the Lost
17%inclusion1 decks6 decks
16%synergy
Vow of Malice
17%inclusion1 decks6 decks
16%synergy
Call of the Ring
17%inclusion1 decks6 decks
14%synergy
Necrodominance
17%inclusion1 decks6 decks
14%synergy
Withering Wisps
17%inclusion1 decks6 decks
16%synergy
Bitterblossom
17%inclusion1 decks6 decks
4%synergy
Necrogen Communion
17%inclusion1 decks6 decks
15%synergy
No Mercy
17%inclusion1 decks6 decks
9%synergy
Planeswalkers
Vraska, Betrayal's Sting
50%inclusion3 decks6 decks
47%synergy
Liliana, Dreadhorde General
17%inclusion1 decks6 decks
3%synergy
Professor Onyx
17%inclusion1 decks6 decks
11%synergy
Liliana Vess
17%inclusion1 decks6 decks
13%synergy
Utility Lands
Cabal Coffers
83%inclusion5 decks6 decks
28%synergy
Karn's Bastion
67%inclusion4 decks6 decks
63%synergy
Castle Locthwain
67%inclusion4 decks6 decks
49%synergy
Urborg, Tomb of Yawgmoth
67%inclusion4 decks6 decks
29%synergy
Rogue's Passage
67%inclusion4 decks6 decks
48%synergy
Phyrexian Tower
50%inclusion3 decks6 decks
25%synergy
Urza's Saga
50%inclusion3 decks6 decks
42%synergy
Inventors' Fair
50%inclusion3 decks6 decks
48%synergy
Bojuka Bog
33%inclusion2 decks6 decks
-14%synergy
Spymaster's Vault
33%inclusion2 decks6 decks
24%synergy
Volrath's Stronghold
33%inclusion2 decks6 decks
30%synergy
Command Beacon
33%inclusion2 decks6 decks
25%synergy
Nykthos, Shrine to Nyx
33%inclusion2 decks6 decks
4%synergy
Witch's Cottage
33%inclusion2 decks6 decks
9%synergy
Susur Secundi, Void Altar
20%inclusion1 decks5 decks
12%synergy
Wasteland
17%inclusion1 decks6 decks
15%synergy
Barren Moor
17%inclusion1 decks6 decks
7%synergy
Hall of the Bandit Lord
17%inclusion1 decks6 decks
16%synergy
Buried Ruin
17%inclusion1 decks6 decks
11%synergy
The Black Gate
17%inclusion1 decks6 decks
13%synergy
Cathedral of War
17%inclusion1 decks6 decks
16%synergy
Emergence Zone
17%inclusion1 decks6 decks
13%synergy
Forge of Heroes
17%inclusion1 decks6 decks
16%synergy
Geier Reach Sanitarium
17%inclusion1 decks6 decks
5%synergy
Diamond Valley
17%inclusion1 decks6 decks
17%synergy
Tomb Fortress
17%inclusion1 decks6 decks
12%synergy
Thespian's Stage
17%inclusion1 decks6 decks
11%synergy
Cryptic Caves
17%inclusion1 decks6 decks
16%synergy
Access Tunnel
17%inclusion1 decks6 decks
14%synergy
Bonders' Enclave
17%inclusion1 decks6 decks
16%synergy
Rishadan Port
17%inclusion1 decks6 decks
17%synergy
Hidden Necropolis
17%inclusion1 decks6 decks
15%synergy
Zhalfirin Void
17%inclusion1 decks6 decks
16%synergy
Mana Artifacts
Sol Ring
100%inclusion6 decks6 decks
14%synergy
Arcane Signet
83%inclusion5 decks6 decks
21%synergy
Glistening Sphere
50%inclusion3 decks6 decks
49%synergy
Mind Stone
50%inclusion3 decks6 decks
20%synergy
Mox Opal
50%inclusion3 decks6 decks
47%synergy
The Soul Stone
50%inclusion2 decks4 decks
36%synergy
Hedron Archive
33%inclusion2 decks6 decks
30%synergy
Lotus Petal
33%inclusion2 decks6 decks
26%synergy
Heraldic Banner
33%inclusion2 decks6 decks
28%synergy
Throne of Eldraine
33%inclusion2 decks6 decks
23%synergy
Mox Amber
33%inclusion2 decks6 decks
29%synergy
Fellwar Stone
33%inclusion2 decks6 decks
19%synergy
Thran Dynamo
33%inclusion2 decks6 decks
27%synergy
Everflowing Chalice
17%inclusion1 decks6 decks
11%synergy
Staff of Compleation
17%inclusion1 decks6 decks
15%synergy
Charcoal Diamond
17%inclusion1 decks6 decks
-6%synergy
Sonic Screwdriver
17%inclusion1 decks6 decks
16%synergy
Sceptre of Eternal Glory
17%inclusion1 decks6 decks
8%synergy
Mox Jasper
17%inclusion1 decks6 decks
17%synergy
Jeweled Amulet
17%inclusion1 decks6 decks
16%synergy
Commander's Sphere
17%inclusion1 decks6 decks
8%synergy
Lands
Swamp
83%inclusion5 decks6 decks
-12%synergy
Cavern of Souls
50%inclusion3 decks6 decks
43%synergy
Plaza of Heroes
50%inclusion3 decks6 decks
49%synergy
Hagra Mauling
33%inclusion2 decks6 decks
29%synergy
Fell the Profane
33%inclusion2 decks6 decks
15%synergy
Myriad Landscape
33%inclusion2 decks6 decks
7%synergy
Agadeem's Awakening
33%inclusion2 decks6 decks
26%synergy
Malakir Rebirth
33%inclusion2 decks6 decks
11%synergy
Terramorphic Expanse
17%inclusion1 decks6 decks
14%synergy
The Seedcore
17%inclusion1 decks6 decks
17%synergy
Blackbloom Rogue
17%inclusion1 decks6 decks
16%synergy
Urza's Cave
17%inclusion1 decks6 decks
8%synergy
Mirrex
17%inclusion1 decks6 decks
16%synergy
Verdant Catacombs
17%inclusion1 decks6 decks
13%synergy
Evolving Wilds
17%inclusion1 decks6 decks
13%synergy
Gemstone Caverns
17%inclusion1 decks6 decks
12%synergy
Snow-Covered Swamp
17%inclusion1 decks6 decks
10%synergy
Marsh Flats
17%inclusion1 decks6 decks
13%synergy
Polluted Delta
17%inclusion1 decks6 decks
13%synergy
Bloodstained Mire
17%inclusion1 decks6 decks
13%synergy
Boggart Trawler
17%inclusion1 decks6 decks
8%synergy
Opal Palace
17%inclusion1 decks6 decks
16%synergy
Zof Consumption
17%inclusion1 decks6 decks
16%synergy
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