Skithiryx, the Blight Dragon (Commander) - Expensive Upgraded Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #780
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Sword of Truth and Justice
80%inclusion4 decks5 decks
79%synergy
Champion's Helm
80%inclusion4 decks5 decks
78%synergy
Vraska's Fall
80%inclusion4 decks5 decks
76%synergy
Commander's Plate
80%inclusion4 decks5 decks
74%synergy
Shizo, Death's Storehouse
80%inclusion4 decks5 decks
70%synergy
Black Market Connections
80%inclusion4 decks5 decks
57%synergy
Imp's Mischief
80%inclusion4 decks5 decks
56%synergy
Withering Torment
80%inclusion4 decks5 decks
48%synergy
Urborg, Tomb of Yawgmoth
80%inclusion4 decks5 decks
42%synergy
Cabal Coffers
80%inclusion4 decks5 decks
25%synergy
Top Cards
Dark Ritual
80%inclusion4 decks5 decks
13%synergy
Jet Medallion
80%inclusion4 decks5 decks
19%synergy
Game Changers
Demonic Tutor
80%inclusion4 decks5 decks
52%synergy
Vampiric Tutor
60%inclusion3 decks5 decks
39%synergy
Imperial Seal
40%inclusion2 decks5 decks
33%synergy
Ancient Tomb
40%inclusion2 decks5 decks
28%synergy
Opposition Agent
20%inclusion1 decks5 decks
10%synergy
The One Ring
20%inclusion1 decks5 decks
10%synergy
Mana Vault
20%inclusion1 decks5 decks
13%synergy
Tergrid, God of Fright
20%inclusion1 decks5 decks
12%synergy
Necropotence
20%inclusion1 decks5 decks
5%synergy
Mishra's Workshop
20%inclusion1 decks5 decks
20%synergy
Creatures
Sheoldred, the Apocalypse
60%inclusion3 decks5 decks
45%synergy
Phyrexian Crusader
60%inclusion3 decks5 decks
59%synergy
Crypt Ghast
60%inclusion3 decks5 decks
12%synergy
Leaden Myr
60%inclusion3 decks5 decks
54%synergy
Plague Stinger
40%inclusion2 decks5 decks
39%synergy
Plague Myr
40%inclusion2 decks5 decks
39%synergy
Flensermite
40%inclusion2 decks5 decks
39%synergy
K'rrik, Son of Yawgmoth
40%inclusion2 decks5 decks
21%synergy
Blood Pet
40%inclusion2 decks5 decks
32%synergy
Solemn Simulacrum
20%inclusion1 decks5 decks
-3%synergy
Dread
20%inclusion1 decks5 decks
20%synergy
Tree of Perdition
20%inclusion1 decks5 decks
18%synergy
Maha, Its Feathers Night
20%inclusion1 decks5 decks
15%synergy
Dread Presence
20%inclusion1 decks5 decks
5%synergy
Whispering Specter
20%inclusion1 decks5 decks
19%synergy
Erebos, God of the Dead
20%inclusion1 decks5 decks
15%synergy
Scrawling Crawler
20%inclusion1 decks5 decks
16%synergy
Plaguecrafter
20%inclusion1 decks5 decks
0%synergy
Sidisi, Undead Vizier
20%inclusion1 decks5 decks
16%synergy
Blackbloom Rogue
20%inclusion1 decks5 decks
19%synergy
Gray Merchant of Asphodel
20%inclusion1 decks5 decks
-32%synergy
Ornithopter of Paradise
20%inclusion1 decks5 decks
17%synergy
Phyrexian Obliterator
20%inclusion1 decks5 decks
9%synergy
Bloodletter of Aclazotz
20%inclusion1 decks5 decks
9%synergy
Mikaeus, the Unhallowed
20%inclusion1 decks5 decks
12%synergy
Banehound
20%inclusion1 decks5 decks
19%synergy
Boggart Trawler
20%inclusion1 decks5 decks
11%synergy
Zhentarim Bandit
20%inclusion1 decks5 decks
19%synergy
Burnished Hart
20%inclusion1 decks5 decks
12%synergy
Sheoldred, Whispering One
20%inclusion1 decks5 decks
8%synergy
Gix, Yawgmoth Praetor
20%inclusion1 decks5 decks
15%synergy
Xiahou Dun, the One-Eyed
20%inclusion1 decks5 decks
20%synergy
Callous Bloodmage
20%inclusion1 decks5 decks
19%synergy
Sheoldred
20%inclusion1 decks5 decks
14%synergy
Kiku, Night's Flower
20%inclusion1 decks5 decks
20%synergy
Royal Assassin
20%inclusion1 decks5 decks
17%synergy
Yawgmoth, Thran Physician
20%inclusion1 decks5 decks
10%synergy
Sheoldred's Headcleaver
20%inclusion1 decks5 decks
20%synergy
Flesh-Eater Imp
20%inclusion1 decks5 decks
19%synergy
Qarsi Revenant
20%inclusion1 decks5 decks
15%synergy
Kokusho, the Evening Star
20%inclusion1 decks5 decks
16%synergy
Accursed Marauder
20%inclusion1 decks5 decks
-1%synergy
Bloodgift Demon
20%inclusion1 decks5 decks
17%synergy
Orcish Bowmasters
20%inclusion1 decks5 decks
6%synergy
Dauthi Voidwalker
20%inclusion1 decks5 decks
4%synergy
Ichor Rats
20%inclusion1 decks5 decks
17%synergy
Bloodthirsty Conqueror
20%inclusion1 decks5 decks
11%synergy
Elegy Acolyte
20%inclusion1 decks5 decks
17%synergy
Instants
Astarion's Thirst
60%inclusion3 decks5 decks
59%synergy
Deadly Rollick
60%inclusion3 decks5 decks
36%synergy
Withering Boon
60%inclusion3 decks5 decks
56%synergy
Tainted Strike
60%inclusion3 decks5 decks
57%synergy
Archenemy's Charm
60%inclusion3 decks5 decks
51%synergy
Fell the Profane
40%inclusion2 decks5 decks
21%synergy
Stinging Study
40%inclusion2 decks5 decks
37%synergy
Go for the Throat
40%inclusion2 decks5 decks
17%synergy
Snuff Out
40%inclusion2 decks5 decks
27%synergy
Hatred
40%inclusion2 decks5 decks
39%synergy
Cabal Ritual
40%inclusion2 decks5 decks
22%synergy
Hagra Mauling
20%inclusion1 decks5 decks
15%synergy
Anoint with Affliction
20%inclusion1 decks5 decks
19%synergy
Howl from Beyond
20%inclusion1 decks5 decks
19%synergy
Defile
20%inclusion1 decks5 decks
-18%synergy
Ulcerate
20%inclusion1 decks5 decks
19%synergy
Slaughter Pact
20%inclusion1 decks5 decks
17%synergy
Rush of Vitality
20%inclusion1 decks5 decks
19%synergy
Bitter Triumph
20%inclusion1 decks5 decks
10%synergy
Darkness
20%inclusion1 decks5 decks
10%synergy
Murder
20%inclusion1 decks5 decks
10%synergy
Infernal Grasp
20%inclusion1 decks5 decks
-5%synergy
Long Goodbye
20%inclusion1 decks5 decks
19%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-3%synergy
Rain of Filth
20%inclusion1 decks5 decks
17%synergy
Baleful Mastery
20%inclusion1 decks5 decks
11%synergy
Liliana's Triumph
20%inclusion1 decks5 decks
14%synergy
Cast Down
20%inclusion1 decks5 decks
18%synergy
Dismember
20%inclusion1 decks5 decks
9%synergy
Sorceries
Phyresis Outbreak
60%inclusion3 decks5 decks
58%synergy
Infectious Inquiry
60%inclusion3 decks5 decks
57%synergy
Night's Whisper
60%inclusion3 decks5 decks
36%synergy
Toxic Deluge
60%inclusion3 decks5 decks
23%synergy
Grim Tutor
60%inclusion3 decks5 decks
48%synergy
Crux of Fate
40%inclusion2 decks5 decks
39%synergy
Blasphemous Edict
40%inclusion2 decks5 decks
23%synergy
Praetor's Grasp
40%inclusion2 decks5 decks
36%synergy
Reanimate
40%inclusion2 decks5 decks
1%synergy
Insatiable Avarice
40%inclusion2 decks5 decks
28%synergy
Sign in Blood
40%inclusion2 decks5 decks
4%synergy
Vat Emergence
20%inclusion1 decks5 decks
18%synergy
Mandate of Abaddon
20%inclusion1 decks5 decks
19%synergy
Torment of Hailfire
20%inclusion1 decks5 decks
4%synergy
Yawgmoth's Will
20%inclusion1 decks5 decks
17%synergy
Bubbling Muck
20%inclusion1 decks5 decks
4%synergy
Blood on the Snow
20%inclusion1 decks5 decks
19%synergy
Agadeem's Awakening
20%inclusion1 decks5 decks
13%synergy
Feed the Swarm
20%inclusion1 decks5 decks
-31%synergy
Read the Bones
20%inclusion1 decks5 decks
2%synergy
Innocent Blood
20%inclusion1 decks5 decks
14%synergy
Yahenni's Expertise
20%inclusion1 decks5 decks
18%synergy
Fell
20%inclusion1 decks5 decks
16%synergy
Gix's Command
20%inclusion1 decks5 decks
18%synergy
Diresight
20%inclusion1 decks5 decks
17%synergy
Syphon Mind
20%inclusion1 decks5 decks
7%synergy
Geth's Summons
20%inclusion1 decks5 decks
20%synergy
Damnation
20%inclusion1 decks5 decks
-1%synergy
Zof Consumption
20%inclusion1 decks5 decks
19%synergy
Mire in Misery
20%inclusion1 decks5 decks
16%synergy
Chain of Smog
20%inclusion1 decks5 decks
15%synergy
Breach the Multiverse
20%inclusion1 decks5 decks
14%synergy
Languish
20%inclusion1 decks5 decks
18%synergy
Zero Point Ballad
20%inclusion1 decks5 decks
18%synergy
Risky Research
20%inclusion1 decks5 decks
19%synergy
Utility Artifacts
Lightning Greaves
60%inclusion3 decks5 decks
26%synergy
Brotherhood Regalia
60%inclusion3 decks5 decks
58%synergy
Blackblade Reforged
60%inclusion3 decks5 decks
57%synergy
Hammer of Nazahn
60%inclusion3 decks5 decks
59%synergy
Mithril Coat
40%inclusion2 decks5 decks
34%synergy
Leyline Axe
40%inclusion2 decks5 decks
39%synergy
Shadowspear
40%inclusion2 decks5 decks
36%synergy
Sword of Wealth and Power
40%inclusion2 decks5 decks
39%synergy
Swiftfoot Boots
40%inclusion2 decks5 decks
8%synergy
Sword of Vengeance
40%inclusion2 decks5 decks
39%synergy
The Darkness Crystal
40%inclusion2 decks5 decks
20%synergy
Doc Ock's Tentacles
33%inclusion1 decks3 decks
33%synergy
Lashwrithe
20%inclusion1 decks5 decks
16%synergy
Sensei's Divining Top
20%inclusion1 decks5 decks
12%synergy
Wayfarer's Bauble
20%inclusion1 decks5 decks
4%synergy
Manifold Key
20%inclusion1 decks5 decks
18%synergy
Thran Power Suit
20%inclusion1 decks5 decks
20%synergy
Nightmare Lash
20%inclusion1 decks5 decks
18%synergy
Heirloom Epic
20%inclusion1 decks5 decks
20%synergy
Strength-Testing Hammer
20%inclusion1 decks5 decks
20%synergy
Lavaspur Boots
20%inclusion1 decks5 decks
18%synergy
Mind's Eye
20%inclusion1 decks5 decks
20%synergy
Skullclamp
20%inclusion1 decks5 decks
-1%synergy
Haunted Cloak
20%inclusion1 decks5 decks
19%synergy
Cranial Plating
20%inclusion1 decks5 decks
16%synergy
Expedition Map
20%inclusion1 decks5 decks
8%synergy
Excalibur, Sword of Eden
20%inclusion1 decks5 decks
20%synergy
Fireshrieker
20%inclusion1 decks5 decks
18%synergy
Inquisitor's Flail
20%inclusion1 decks5 decks
20%synergy
Silver Shroud Costume
20%inclusion1 decks5 decks
19%synergy
Pact Weapon
20%inclusion1 decks5 decks
18%synergy
Grafted Wargear
20%inclusion1 decks5 decks
20%synergy
Helm of Awakening
20%inclusion1 decks5 decks
19%synergy
Dark Knight's Greatsword
20%inclusion1 decks5 decks
20%synergy
Genji Glove
20%inclusion1 decks5 decks
19%synergy
Enchantments
Phyrexian Arena
60%inclusion3 decks5 decks
20%synergy
Unspeakable Symbol
40%inclusion2 decks5 decks
39%synergy
The Meathook Massacre
20%inclusion1 decks5 decks
3%synergy
Vow of Torment
20%inclusion1 decks5 decks
20%synergy
Phyrexian Reclamation
20%inclusion1 decks5 decks
10%synergy
Necromancy
20%inclusion1 decks5 decks
14%synergy
Corpses of the Lost
20%inclusion1 decks5 decks
19%synergy
Vow of Malice
20%inclusion1 decks5 decks
20%synergy
Call of the Ring
20%inclusion1 decks5 decks
18%synergy
Necrodominance
20%inclusion1 decks5 decks
17%synergy
Kaya's Ghostform
20%inclusion1 decks5 decks
10%synergy
Agent of the Shadow Thieves
20%inclusion1 decks5 decks
19%synergy
No Mercy
20%inclusion1 decks5 decks
13%synergy
Animate Dead
20%inclusion1 decks5 decks
2%synergy
Withering Wisps
20%inclusion1 decks5 decks
20%synergy
Necrogen Communion
20%inclusion1 decks5 decks
18%synergy
Planeswalkers
Vraska, Betrayal's Sting
60%inclusion3 decks5 decks
57%synergy
Liliana of the Dark Realms
60%inclusion3 decks5 decks
46%synergy
Professor Onyx
20%inclusion1 decks5 decks
14%synergy
Utility Lands
Inkmoth Nexus
60%inclusion3 decks5 decks
59%synergy
War Room
60%inclusion3 decks5 decks
43%synergy
Castle Locthwain
60%inclusion3 decks5 decks
42%synergy
Rogue's Passage
60%inclusion3 decks5 decks
41%synergy
Phyrexian Tower
40%inclusion2 decks5 decks
16%synergy
Volrath's Stronghold
40%inclusion2 decks5 decks
36%synergy
Karn's Bastion
40%inclusion2 decks5 decks
36%synergy
Bojuka Bog
20%inclusion1 decks5 decks
-27%synergy
Zhalfirin Void
20%inclusion1 decks5 decks
20%synergy
Barren Moor
20%inclusion1 decks5 decks
10%synergy
Hall of the Bandit Lord
20%inclusion1 decks5 decks
19%synergy
The Black Gate
20%inclusion1 decks5 decks
17%synergy
Urza's Saga
20%inclusion1 decks5 decks
12%synergy
Spymaster's Vault
20%inclusion1 decks5 decks
10%synergy
Witch's Cottage
20%inclusion1 decks5 decks
-5%synergy
Emergence Zone
20%inclusion1 decks5 decks
17%synergy
Forge of Heroes
20%inclusion1 decks5 decks
20%synergy
Geier Reach Sanitarium
20%inclusion1 decks5 decks
9%synergy
Command Beacon
20%inclusion1 decks5 decks
12%synergy
Diamond Valley
20%inclusion1 decks5 decks
20%synergy
Nykthos, Shrine to Nyx
20%inclusion1 decks5 decks
-10%synergy
Inventors' Fair
20%inclusion1 decks5 decks
18%synergy
Cryptic Caves
20%inclusion1 decks5 decks
20%synergy
Reliquary Tower
20%inclusion1 decks5 decks
-11%synergy
Access Tunnel
20%inclusion1 decks5 decks
17%synergy
Bonders' Enclave
20%inclusion1 decks5 decks
19%synergy
Rishadan Port
20%inclusion1 decks5 decks
20%synergy
Hidden Necropolis
20%inclusion1 decks5 decks
18%synergy
Susur Secundi, Void Altar
20%inclusion1 decks5 decks
12%synergy
Mana Artifacts
Sol Ring
100%inclusion5 decks5 decks
14%synergy
Arcane Signet
80%inclusion4 decks5 decks
18%synergy
The Soul Stone
75%inclusion3 decks4 decks
62%synergy
Fellwar Stone
60%inclusion3 decks5 decks
45%synergy
Mind Stone
60%inclusion3 decks5 decks
29%synergy
Charcoal Diamond
40%inclusion2 decks5 decks
17%synergy
Glistening Sphere
40%inclusion2 decks5 decks
39%synergy
Lotus Petal
40%inclusion2 decks5 decks
33%synergy
Throne of Eldraine
40%inclusion2 decks5 decks
29%synergy
Sonic Screwdriver
40%inclusion2 decks5 decks
39%synergy
Mox Opal
40%inclusion2 decks5 decks
37%synergy
Lotus Bloom
20%inclusion1 decks5 decks
19%synergy
Everflowing Chalice
20%inclusion1 decks5 decks
14%synergy
Staff of Compleation
20%inclusion1 decks5 decks
18%synergy
Hedron Archive
20%inclusion1 decks5 decks
16%synergy
Heraldic Banner
20%inclusion1 decks5 decks
14%synergy
Mox Amber
20%inclusion1 decks5 decks
16%synergy
Thought Vessel
20%inclusion1 decks5 decks
-7%synergy
Thran Dynamo
20%inclusion1 decks5 decks
14%synergy
Liquimetal Torque
20%inclusion1 decks5 decks
17%synergy
Sceptre of Eternal Glory
20%inclusion1 decks5 decks
11%synergy
Mox Jasper
20%inclusion1 decks5 decks
20%synergy
Chrome Mox
20%inclusion1 decks5 decks
14%synergy
Lands
Swamp
80%inclusion4 decks5 decks
-15%synergy
Cavern of Souls
60%inclusion3 decks5 decks
53%synergy
Fell the Profane
40%inclusion2 decks5 decks
21%synergy
Verdant Catacombs
40%inclusion2 decks5 decks
37%synergy
Plaza of Heroes
40%inclusion2 decks5 decks
39%synergy
Gemstone Caverns
40%inclusion2 decks5 decks
36%synergy
Marsh Flats
40%inclusion2 decks5 decks
37%synergy
Polluted Delta
40%inclusion2 decks5 decks
37%synergy
Bloodstained Mire
40%inclusion2 decks5 decks
36%synergy
Hagra Mauling
20%inclusion1 decks5 decks
15%synergy
Terramorphic Expanse
20%inclusion1 decks5 decks
17%synergy
Myriad Landscape
20%inclusion1 decks5 decks
-6%synergy
Blackbloom Rogue
20%inclusion1 decks5 decks
19%synergy
Urza's Cave
20%inclusion1 decks5 decks
11%synergy
Agadeem's Awakening
20%inclusion1 decks5 decks
13%synergy
Boggart Trawler
20%inclusion1 decks5 decks
11%synergy
Talon Gates of Madara
20%inclusion1 decks5 decks
18%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-3%synergy
Evolving Wilds
20%inclusion1 decks5 decks
16%synergy
Opal Palace
20%inclusion1 decks5 decks
19%synergy
Snow-Covered Swamp
20%inclusion1 decks5 decks
13%synergy
Zof Consumption
20%inclusion1 decks5 decks
19%synergy
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