Skithiryx, the Blight Dragon (Commander) - Expensive Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #790
75decks
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Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Bitterbloom Bearer
9.1%inclusion1 decks11 decks
7%synergy
High Synergy Cards
Plague Stinger
76%inclusion57 decks75 decks
75%synergy
Plague Myr
76%inclusion57 decks75 decks
75%synergy
Inkmoth Nexus
75%inclusion56 decks75 decks
74%synergy
Ichor Rats
75%inclusion56 decks75 decks
71%synergy
Phyrexian Crusader
72%inclusion54 decks75 decks
71%synergy
Shizo, Death's Storehouse
80%inclusion60 decks75 decks
70%synergy
Infectious Inquiry
72%inclusion54 decks75 decks
69%synergy
Whispering Specter
68%inclusion51 decks75 decks
67%synergy
Commander's Plate
71%inclusion53 decks75 decks
65%synergy
Hand of the Praetors
65%inclusion49 decks75 decks
65%synergy
Top Cards
Dark Ritual
93%inclusion70 decks75 decks
27%synergy
Deadly Rollick
81%inclusion61 decks75 decks
58%synergy
Toxic Deluge
76%inclusion57 decks75 decks
39%synergy
Jet Medallion
76%inclusion57 decks75 decks
16%synergy
Lightning Greaves
68%inclusion51 decks75 decks
34%synergy
Cabal Ritual
65%inclusion49 decks75 decks
48%synergy
Shadowspear
64%inclusion48 decks75 decks
60%synergy
Phyresis Outbreak
63%inclusion47 decks75 decks
61%synergy
Unspeakable Symbol
63%inclusion47 decks75 decks
62%synergy
Vraska's Fall
61%inclusion46 decks75 decks
58%synergy
Game Changers
Ancient Tomb
92%inclusion69 decks75 decks
80%synergy
Demonic Tutor
89%inclusion67 decks75 decks
62%synergy
Vampiric Tutor
87%inclusion65 decks75 decks
65%synergy
Mana Vault
81%inclusion61 decks75 decks
74%synergy
Chrome Mox
76%inclusion57 decks75 decks
70%synergy
Necropotence
61%inclusion46 decks75 decks
46%synergy
Mox Diamond
55%inclusion41 decks75 decks
51%synergy
The One Ring
52%inclusion39 decks75 decks
42%synergy
Opposition Agent
48%inclusion36 decks75 decks
38%synergy
Imperial Seal
41%inclusion31 decks75 decks
34%synergy
Creatures
Crypt Ghast
56%inclusion42 decks75 decks
8%synergy
Dauthi Voidwalker
45%inclusion34 decks75 decks
30%synergy
Blightbelly Rat
44%inclusion33 decks75 decks
40%synergy
K'rrik, Son of Yawgmoth
44%inclusion33 decks75 decks
25%synergy
Orcish Bowmasters
40%inclusion30 decks75 decks
26%synergy
Dark Confidant
36%inclusion27 decks75 decks
29%synergy
Yawgmoth, Thran Physician
33%inclusion25 decks75 decks
23%synergy
Bilious Skulldweller
29%inclusion22 decks75 decks
28%synergy
Myr Convert
27%inclusion20 decks75 decks
26%synergy
Flensermite
25%inclusion19 decks75 decks
25%synergy
Ichorclaw Myr
25%inclusion19 decks75 decks
25%synergy
Sheoldred, the Apocalypse
24%inclusion18 decks75 decks
9%synergy
Reaper of Sheoldred
19%inclusion14 decks75 decks
18%synergy
Flesh-Eater Imp
19%inclusion14 decks75 decks
18%synergy
Necropede
19%inclusion14 decks75 decks
18%synergy
Blightsteel Colossus
19%inclusion14 decks75 decks
18%synergy
Corpse Cur
17%inclusion13 decks75 decks
17%synergy
Septic Rats
17%inclusion13 decks75 decks
15%synergy
Core Prowler
16%inclusion12 decks75 decks
15%synergy
Pestilent Syphoner
16%inclusion12 decks75 decks
15%synergy
Phyrexian Obliterator
16%inclusion12 decks75 decks
5%synergy
Phyrexian Vatmother
16%inclusion12 decks75 decks
16%synergy
Gray Merchant of Asphodel
15%inclusion11 decks75 decks
-37%synergy
Massacre Girl, Known Killer
14%inclusion10 decks74 decks
10%synergy
Surge Conductor
13%inclusion2 decks15 decks
13%synergy
Filth
9.3%inclusion7 decks75 decks
7%synergy
Maha, Its Feathers Night
9.1%inclusion5 decks55 decks
4%synergy
Agent Venom
8.3%inclusion1 decks12 decks
6%synergy
Blackcleave Goblin
8.0%inclusion6 decks75 decks
8%synergy
Necroskitter
8.0%inclusion6 decks75 decks
5%synergy
Grafted Butcher
8.0%inclusion6 decks75 decks
8%synergy
Phyrexian Digester
8.0%inclusion6 decks75 decks
8%synergy
Bloodthirsty Conqueror
7.9%inclusion3 decks38 decks
-1%synergy
Magus of the Coffers
6.7%inclusion5 decks75 decks
-1%synergy
Witch-king of Angmar
6.7%inclusion5 decks75 decks
5%synergy
Defiler of Flesh
6.7%inclusion5 decks75 decks
2%synergy
Swamp Mosquito
6.7%inclusion5 decks75 decks
7%synergy
Mikaeus, the Unhallowed
6.7%inclusion5 decks75 decks
-1%synergy
Nirkana Revenant
6.7%inclusion5 decks75 decks
-5%synergy
Massacre Wurm
6.7%inclusion5 decks75 decks
-11%synergy
Leaden Myr
6.7%inclusion5 decks75 decks
0%synergy
Virulent Silencer
6.7%inclusion1 decks15 decks
6%synergy
Unstoppable Slasher
6.0%inclusion3 decks50 decks
0%synergy
Solemn Simulacrum
5.3%inclusion4 decks75 decks
-18%synergy
Contagious Nim
5.3%inclusion4 decks75 decks
5%synergy
Murderous Rider
5.3%inclusion4 decks75 decks
-1%synergy
Nazgûl
5.3%inclusion4 decks75 decks
5%synergy
Sheoldred, Whispering One
5.3%inclusion4 decks75 decks
-7%synergy
Braids, Arisen Nightmare
5.3%inclusion4 decks75 decks
-14%synergy
Instants
Tainted Strike
52%inclusion39 decks75 decks
49%synergy
Snuff Out
51%inclusion38 decks75 decks
38%synergy
Hatred
51%inclusion38 decks75 decks
50%synergy
Imp's Mischief
48%inclusion36 decks75 decks
24%synergy
Dismember
48%inclusion36 decks75 decks
37%synergy
Howl from Beyond
43%inclusion32 decks75 decks
42%synergy
Withering Torment
28%inclusion14 decks50 decks
-4%synergy
Malakir Rebirth
27%inclusion20 decks75 decks
4%synergy
Go for the Throat
25%inclusion19 decks75 decks
2%synergy
Whisper of the Dross
23%inclusion17 decks75 decks
19%synergy
Defile
21%inclusion16 decks75 decks
-16%synergy
Withering Boon
21%inclusion16 decks75 decks
17%synergy
Baleful Mastery
21%inclusion16 decks75 decks
12%synergy
Sudden Spoiling
21%inclusion16 decks75 decks
12%synergy
Force of Despair
20%inclusion15 decks75 decks
12%synergy
Culling the Weak
20%inclusion15 decks75 decks
5%synergy
Infernal Grasp
20%inclusion15 decks75 decks
-5%synergy
Archenemy's Charm
20%inclusion3 decks15 decks
11%synergy
Fell the Profane
18%inclusion11 decks60 decks
0%synergy
Cut Down
16%inclusion12 decks75 decks
12%synergy
Darkness
16%inclusion12 decks75 decks
7%synergy
Hero's Downfall
13%inclusion10 decks75 decks
6%synergy
Bitter Triumph
13%inclusion10 decks75 decks
3%synergy
Astarion's Thirst
12%inclusion9 decks75 decks
11%synergy
Slaughter Pact
12%inclusion9 decks75 decks
9%synergy
Consuming Corruption
10%inclusion6 decks60 decks
-6%synergy
Ad Nauseam
9.3%inclusion7 decks75 decks
7%synergy
Blood Pact
8.0%inclusion6 decks75 decks
4%synergy
Grim Affliction
6.7%inclusion5 decks75 decks
4%synergy
Tragic Slip
6.7%inclusion5 decks75 decks
-14%synergy
Overkill
6.3%inclusion1 decks16 decks
-1%synergy
Sheoldred's Edict
5.3%inclusion4 decks75 decks
-9%synergy
Entomb
5.3%inclusion4 decks75 decks
-7%synergy
Not Dead After All
5.3%inclusion4 decks75 decks
-6%synergy
Supernatural Stamina
5.3%inclusion4 decks75 decks
-2%synergy
Virulent Wound
5.3%inclusion4 decks75 decks
5%synergy
Rain of Filth
5.3%inclusion4 decks75 decks
3%synergy
Sorceries
Feed the Swarm
60%inclusion45 decks75 decks
9%synergy
Night's Whisper
53%inclusion40 decks75 decks
29%synergy
Sign in Blood
49%inclusion37 decks75 decks
13%synergy
Drown in Ichor
49%inclusion37 decks75 decks
45%synergy
Bubbling Muck
48%inclusion36 decks75 decks
32%synergy
Crux of Fate
47%inclusion35 decks75 decks
45%synergy
Damnation
45%inclusion34 decks75 decks
24%synergy
Insatiable Avarice
33%inclusion21 decks64 decks
21%synergy
Reanimate
32%inclusion24 decks75 decks
-7%synergy
Grim Tutor
32%inclusion24 decks75 decks
20%synergy
Praetor's Grasp
21%inclusion16 decks75 decks
17%synergy
Blasphemous Edict
19%inclusion7 decks37 decks
2%synergy
Caress of Phyrexia
17%inclusion13 decks75 decks
17%synergy
Beseech the Mirror
15%inclusion11 decks75 decks
8%synergy
Yawgmoth's Will
13%inclusion10 decks75 decks
10%synergy
Read the Bones
12%inclusion9 decks75 decks
-6%synergy
Black Sun's Zenith
11%inclusion8 decks75 decks
5%synergy
Torment of Hailfire
11%inclusion8 decks75 decks
-5%synergy
Exsanguinate
6.7%inclusion5 decks75 decks
-18%synergy
Diabolic Tutor
5.3%inclusion4 decks75 decks
-10%synergy
Peer into the Abyss
5.3%inclusion4 decks75 decks
-6%synergy
Agadeem's Awakening
5.3%inclusion4 decks75 decks
-2%synergy
Dark Petition
5.3%inclusion4 decks75 decks
1%synergy
Geth's Summons
5.3%inclusion4 decks75 decks
5%synergy
Beseech the Queen
5.3%inclusion4 decks75 decks
-1%synergy
Thoughtseize
5.3%inclusion4 decks75 decks
0%synergy
Utility Artifacts
Swiftfoot Boots
57%inclusion43 decks75 decks
26%synergy
Sword of Truth and Justice
52%inclusion39 decks75 decks
51%synergy
Lashwrithe
49%inclusion37 decks75 decks
45%synergy
Nightmare Lash
48%inclusion36 decks75 decks
46%synergy
Blackblade Reforged
39%inclusion29 decks75 decks
36%synergy
Sensei's Divining Top
37%inclusion28 decks75 decks
29%synergy
Cranial Plating
32%inclusion24 decks75 decks
28%synergy
Bolas's Citadel
31%inclusion23 decks75 decks
1%synergy
Mithril Coat
28%inclusion21 decks75 decks
22%synergy
The Darkness Crystal
28%inclusion5 decks18 decks
8%synergy
Sword of Feast and Famine
25%inclusion19 decks75 decks
24%synergy
Genji Glove
25%inclusion4 decks16 decks
24%synergy
Whispersilk Cloak
23%inclusion17 decks75 decks
17%synergy
Champion's Helm
20%inclusion15 decks75 decks
18%synergy
Doc Ock's Tentacles
18%inclusion2 decks11 decks
18%synergy
Pip-Boy 3000
18%inclusion13 decks72 decks
18%synergy
Umezawa's Jitte
17%inclusion13 decks75 decks
17%synergy
Contagion Engine
17%inclusion13 decks75 decks
15%synergy
Black Mage's Rod
17%inclusion3 decks18 decks
16%synergy
Fireshrieker
16%inclusion12 decks75 decks
14%synergy
Pact Weapon
16%inclusion12 decks75 decks
14%synergy
Leyline Axe
16%inclusion6 decks38 decks
15%synergy
Wishclaw Talisman
15%inclusion11 decks75 decks
8%synergy
Manifold Key
13%inclusion10 decks75 decks
12%synergy
Expedition Map
13%inclusion10 decks75 decks
1%synergy
Sword of the Animist
13%inclusion10 decks75 decks
9%synergy
Hammer of Nazahn
13%inclusion10 decks75 decks
13%synergy
Brotherhood Regalia
12%inclusion7 decks57 decks
10%synergy
Contagion Clasp
12%inclusion9 decks75 decks
9%synergy
Throne of Geth
12%inclusion9 decks75 decks
12%synergy
Sword of Wealth and Power
11%inclusion8 decks72 decks
10%synergy
Hero's Blade
11%inclusion8 decks75 decks
10%synergy
Sword of Fire and Ice
9.3%inclusion7 decks75 decks
9%synergy
Aetherflux Reservoir
9.3%inclusion7 decks75 decks
-1%synergy
Thran Power Suit
8.0%inclusion6 decks75 decks
8%synergy
Trailblazer's Boots
8.0%inclusion6 decks75 decks
6%synergy
Sword of Hearth and Home
8.0%inclusion6 decks75 decks
7%synergy
Conqueror's Flail
8.0%inclusion6 decks75 decks
7%synergy
Grafted Wargear
8.0%inclusion6 decks75 decks
8%synergy
Lavaspur Boots
7.7%inclusion5 decks65 decks
6%synergy
Voltaic Key
6.7%inclusion5 decks75 decks
6%synergy
Helm of Obedience
6.7%inclusion5 decks75 decks
6%synergy
O-Naginata
6.7%inclusion5 decks75 decks
6%synergy
Bloodforged Battle-Axe
6.7%inclusion5 decks75 decks
6%synergy
Sword of Sinew and Steel
6.7%inclusion5 decks75 decks
6%synergy
Dark Knight's Greatsword
6.3%inclusion1 decks16 decks
6%synergy
Buster Sword
5.9%inclusion1 decks17 decks
5%synergy
Aettir and Priwen
5.9%inclusion1 decks17 decks
6%synergy
Radiant Lotus
5.6%inclusion1 decks18 decks
5%synergy
Silver Shroud Costume
5.6%inclusion4 decks72 decks
4%synergy
Enchantments
Phyrexian Arena
59%inclusion44 decks75 decks
18%synergy
Black Market Connections
52%inclusion39 decks75 decks
29%synergy
Necrogen Communion
35%inclusion26 decks75 decks
33%synergy
Super State
27%inclusion4 decks15 decks
26%synergy
The Meathook Massacre
21%inclusion16 decks75 decks
4%synergy
Kaya's Ghostform
16%inclusion12 decks75 decks
6%synergy
Animate Dead
16%inclusion12 decks75 decks
-2%synergy
Phyresis
15%inclusion11 decks75 decks
12%synergy
No Mercy
15%inclusion11 decks75 decks
7%synergy
Contamination
13%inclusion10 decks75 decks
10%synergy
Oubliette
11%inclusion8 decks75 decks
8%synergy
Leyline of the Void
11%inclusion8 decks75 decks
9%synergy
Bitterblossom
11%inclusion8 decks75 decks
-2%synergy
Endless Scream
9.3%inclusion7 decks75 decks
9%synergy
Glistening Oil
8.0%inclusion6 decks75 decks
7%synergy
Phyrexian Reclamation
8.0%inclusion6 decks75 decks
-2%synergy
Shade's Form
8.0%inclusion6 decks75 decks
7%synergy
Bloodchief Ascension
8.0%inclusion6 decks75 decks
-2%synergy
Bad Moon
8.0%inclusion6 decks75 decks
5%synergy
Relic Putrescence
6.7%inclusion5 decks75 decks
6%synergy
Heartless Summoning
6.7%inclusion5 decks75 decks
2%synergy
Call of the Ring
5.3%inclusion4 decks75 decks
3%synergy
Dauthi Embrace
5.3%inclusion4 decks75 decks
4%synergy
Infernal Darkness
5.3%inclusion4 decks75 decks
5%synergy
Planeswalkers
Vraska, Betrayal's Sting
51%inclusion38 decks75 decks
48%synergy
Liliana of the Dark Realms
35%inclusion26 decks75 decks
21%synergy
Tezzeret, Cruel Captain
13%inclusion2 decks15 decks
12%synergy
Utility Lands
Cabal Coffers
88%inclusion66 decks75 decks
33%synergy
Urborg, Tomb of Yawgmoth
88%inclusion66 decks75 decks
50%synergy
Karn's Bastion
64%inclusion48 decks75 decks
60%synergy
Rogue's Passage
60%inclusion45 decks75 decks
42%synergy
Urza's Saga
49%inclusion37 decks75 decks
41%synergy
Lake of the Dead
45%inclusion34 decks75 decks
40%synergy
Nykthos, Shrine to Nyx
37%inclusion28 decks75 decks
8%synergy
The Black Gate
36%inclusion27 decks75 decks
33%synergy
Strip Mine
35%inclusion26 decks75 decks
32%synergy
Bojuka Bog
33%inclusion25 decks75 decks
-13%synergy
Command Beacon
24%inclusion18 decks75 decks
16%synergy
Cabal Stronghold
23%inclusion17 decks75 decks
-13%synergy
Minas Morgul, Dark Fortress
21%inclusion16 decks75 decks
18%synergy
Vault of Whispers
20%inclusion15 decks75 decks
14%synergy
Takenuma, Abandoned Mire
20%inclusion15 decks75 decks
4%synergy
Castle Locthwain
20%inclusion15 decks75 decks
2%synergy
Homeward Path
17%inclusion13 decks75 decks
16%synergy
Volrath's Stronghold
15%inclusion11 decks75 decks
11%synergy
Phyrexian Tower
13%inclusion10 decks75 decks
-11%synergy
Wasteland
12%inclusion9 decks75 decks
10%synergy
Cathedral of War
12%inclusion9 decks75 decks
12%synergy
Reliquary Tower
11%inclusion8 decks75 decks
-21%synergy
City of Traitors
11%inclusion8 decks75 decks
9%synergy
War Room
9.3%inclusion7 decks75 decks
-7%synergy
Maze of Ith
8.0%inclusion6 decks75 decks
5%synergy
Deserted Temple
8.0%inclusion6 decks75 decks
4%synergy
Temple of the False God
6.7%inclusion5 decks75 decks
-1%synergy
Midgar, City of Mako
6.3%inclusion1 decks16 decks
-6%synergy
Hall of the Bandit Lord
5.3%inclusion4 decks75 decks
4%synergy
Darksteel Citadel
5.3%inclusion4 decks75 decks
4%synergy
Thespian's Stage
5.3%inclusion4 decks75 decks
0%synergy
Mishra's Workshop
5.3%inclusion4 decks75 decks
5%synergy
Dark Depths
5.3%inclusion4 decks75 decks
5%synergy
Spymaster's Vault
5.0%inclusion3 decks60 decks
-5%synergy
Mana Artifacts
Sol Ring
97%inclusion73 decks75 decks
11%synergy
Arcane Signet
81%inclusion61 decks75 decks
19%synergy
Mox Opal
71%inclusion53 decks75 decks
67%synergy
Lotus Petal
64%inclusion48 decks75 decks
57%synergy
Glistening Sphere
43%inclusion32 decks75 decks
41%synergy
The Soul Stone
40%inclusion6 decks15 decks
27%synergy
Grim Monolith
37%inclusion28 decks75 decks
34%synergy
Staff of Compleation
33%inclusion25 decks75 decks
32%synergy
Mana Crypt
31%inclusion23 decks75 decks
28%synergy
Jeweled Lotus
29%inclusion22 decks75 decks
27%synergy
Mox Amber
25%inclusion19 decks75 decks
21%synergy
Fellwar Stone
23%inclusion17 decks75 decks
8%synergy
Throne of Eldraine
21%inclusion16 decks75 decks
11%synergy
Mind Stone
21%inclusion16 decks75 decks
-10%synergy
Mox Jasper
17%inclusion3 decks18 decks
17%synergy
Everflowing Chalice
12%inclusion9 decks75 decks
6%synergy
Heraldic Banner
12%inclusion9 decks75 decks
6%synergy
Caged Sun
9.3%inclusion7 decks75 decks
-3%synergy
Thran Dynamo
9.3%inclusion7 decks75 decks
3%synergy
Sceptre of Eternal Glory
9.3%inclusion7 decks75 decks
0%synergy
Charcoal Diamond
6.7%inclusion5 decks75 decks
-17%synergy
Thought Vessel
6.7%inclusion5 decks75 decks
-20%synergy
Mox Tantalite
6.7%inclusion5 decks75 decks
6%synergy
Extraplanar Lens
6.7%inclusion5 decks75 decks
2%synergy
Patchwork Banner
5.5%inclusion3 decks55 decks
1%synergy
Gauntlet of Power
5.3%inclusion4 decks75 decks
2%synergy
Gilded Lotus
5.3%inclusion4 decks75 decks
0%synergy
Worn Powerstone
5.3%inclusion4 decks75 decks
1%synergy
Lands
Swamp
89%inclusion67 decks75 decks
-5%synergy
Cavern of Souls
71%inclusion53 decks75 decks
64%synergy
Gemstone Caverns
35%inclusion26 decks75 decks
30%synergy
Malakir Rebirth
27%inclusion20 decks75 decks
4%synergy
Verdant Catacombs
24%inclusion18 decks75 decks
21%synergy
Polluted Delta
23%inclusion17 decks75 decks
19%synergy
Bloodstained Mire
23%inclusion17 decks75 decks
19%synergy
Marsh Flats
21%inclusion16 decks75 decks
18%synergy
Fell the Profane
18%inclusion11 decks60 decks
0%synergy
Plaza of Heroes
15%inclusion11 decks75 decks
14%synergy
Mirrex
13%inclusion10 decks75 decks
13%synergy
Snow-Covered Swamp
13%inclusion10 decks75 decks
6%synergy
Prismatic Vista
9.3%inclusion7 decks75 decks
7%synergy
Command Tower
9.3%inclusion7 decks75 decks
4%synergy
Fabled Passage
6.7%inclusion5 decks75 decks
5%synergy
Myriad Landscape
6.7%inclusion5 decks75 decks
-20%synergy
Urza's Cave
6.5%inclusion4 decks62 decks
-2%synergy
The Seedcore
5.3%inclusion4 decks75 decks
5%synergy
Agadeem's Awakening
5.3%inclusion4 decks75 decks
-2%synergy
Opal Palace
5.3%inclusion4 decks75 decks
5%synergy
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