Skithiryx, the Blight Dragon (Commander) - cEDH Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #793
3decks
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Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
Mana Artifacts
Lands
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Demonic Tutor
100%inclusion3 decks3 decks
73%synergy
Ancient Tomb
67%inclusion2 decks3 decks
55%synergy
Bolas's Citadel
67%inclusion2 decks3 decks
38%synergy
Mana Vault
67%inclusion2 decks3 decks
60%synergy
Chrome Mox
67%inclusion2 decks3 decks
61%synergy
Vampiric Tutor
67%inclusion2 decks3 decks
46%synergy
Imperial Seal
33%inclusion1 decks3 decks
26%synergy
The One Ring
33%inclusion1 decks3 decks
24%synergy
Ad Nauseam
33%inclusion1 decks3 decks
30%synergy
Creatures
K'rrik, Son of Yawgmoth
67%inclusion2 decks3 decks
47%synergy
Dauthi Voidwalker
67%inclusion2 decks3 decks
51%synergy
Plague Stinger
33%inclusion1 decks3 decks
32%synergy
Nefarox, Overlord of Grixis
33%inclusion1 decks3 decks
33%synergy
Pestilent Syphoner
33%inclusion1 decks3 decks
33%synergy
Grim Servant
33%inclusion1 decks3 decks
29%synergy
Silent Arbiter
33%inclusion1 decks3 decks
32%synergy
Erebos, God of the Dead
33%inclusion1 decks3 decks
29%synergy
Witch-king of Angmar
33%inclusion1 decks3 decks
32%synergy
Necrotic Ooze
33%inclusion1 decks3 decks
29%synergy
Sheoldred, the Apocalypse
33%inclusion1 decks3 decks
19%synergy
Dimir House Guard
33%inclusion1 decks3 decks
30%synergy
Gray Merchant of Asphodel
33%inclusion1 decks3 decks
-17%synergy
Phyrexian Obliterator
33%inclusion1 decks3 decks
22%synergy
Duty-Bound Dead
33%inclusion1 decks3 decks
33%synergy
Bloodletter of Aclazotz
33%inclusion1 decks3 decks
23%synergy
Nazgûl
33%inclusion1 decks3 decks
33%synergy
Unstoppable Slasher
33%inclusion1 decks3 decks
28%synergy
Myr Convert
33%inclusion1 decks3 decks
33%synergy
Vito, Thorn of the Dusk Rose
33%inclusion1 decks3 decks
23%synergy
Bilious Skulldweller
33%inclusion1 decks3 decks
32%synergy
Servant of Nefarox
33%inclusion1 decks3 decks
33%synergy
Phyrexian Crusader
33%inclusion1 decks3 decks
32%synergy
Massacre Wurm
33%inclusion1 decks3 decks
16%synergy
Duskmantle Prowler
33%inclusion1 decks3 decks
33%synergy
Archfiend of Despair
33%inclusion1 decks3 decks
31%synergy
Crypt Ghast
33%inclusion1 decks3 decks
-14%synergy
Chainer, Dementia Master
33%inclusion1 decks3 decks
29%synergy
Plague Engineer
33%inclusion1 decks3 decks
33%synergy
Knight of Infamy
33%inclusion1 decks3 decks
33%synergy
Viscera Seer
33%inclusion1 decks3 decks
16%synergy
Bloodthirsty Conqueror
33%inclusion1 decks3 decks
24%synergy
Instants
Go for the Throat
100%inclusion3 decks3 decks
77%synergy
Dark Ritual
100%inclusion3 decks3 decks
33%synergy
Cabal Ritual
67%inclusion2 decks3 decks
48%synergy
Dismember
67%inclusion2 decks3 decks
56%synergy
Hero's Downfall
33%inclusion1 decks3 decks
27%synergy
Deadly Rollick
33%inclusion1 decks3 decks
8%synergy
Fell the Profane
33%inclusion1 decks3 decks
14%synergy
Whisper of the Dross
33%inclusion1 decks3 decks
31%synergy
Entomb
33%inclusion1 decks3 decks
21%synergy
Snuff Out
33%inclusion1 decks3 decks
20%synergy
Vraska's Fall
33%inclusion1 decks3 decks
30%synergy
Anoint with Affliction
33%inclusion1 decks3 decks
33%synergy
Howl from Beyond
33%inclusion1 decks3 decks
33%synergy
Hatred
33%inclusion1 decks3 decks
32%synergy
Doom Blade
33%inclusion1 decks3 decks
26%synergy
Unnatural Endurance
33%inclusion1 decks3 decks
33%synergy
Slaughter Pact
33%inclusion1 decks3 decks
31%synergy
Bitter Triumph
33%inclusion1 decks3 decks
23%synergy
Virulent Swipe
33%inclusion1 decks3 decks
33%synergy
Tendrils of Corruption
33%inclusion1 decks3 decks
30%synergy
Funeral Charm
33%inclusion1 decks3 decks
33%synergy
Tainted Strike
33%inclusion1 decks3 decks
30%synergy
Unmake the Graves
33%inclusion1 decks3 decks
33%synergy
Sudden Spoiling
33%inclusion1 decks3 decks
25%synergy
Withering Torment
33%inclusion1 decks3 decks
2%synergy
Sorceries
Feed the Swarm
100%inclusion3 decks3 decks
50%synergy
Bubbling Muck
67%inclusion2 decks3 decks
51%synergy
Crux of Fate
67%inclusion2 decks3 decks
65%synergy
Infectious Inquiry
67%inclusion2 decks3 decks
64%synergy
Sign in Blood
67%inclusion2 decks3 decks
32%synergy
Diabolic Intent
33%inclusion1 decks3 decks
18%synergy
Diabolic Tutor
33%inclusion1 decks3 decks
19%synergy
Mandate of Abaddon
33%inclusion1 decks3 decks
32%synergy
Victimize
33%inclusion1 decks3 decks
6%synergy
Profane Tutor
33%inclusion1 decks3 decks
29%synergy
Dread Return
33%inclusion1 decks3 decks
21%synergy
Inquisition of Kozilek
33%inclusion1 decks3 decks
31%synergy
Phyresis Outbreak
33%inclusion1 decks3 decks
32%synergy
Mastermind's Acquisition
33%inclusion1 decks3 decks
32%synergy
Praetor's Grasp
33%inclusion1 decks3 decks
29%synergy
Chainer's Edict
33%inclusion1 decks3 decks
33%synergy
Dark Petition
33%inclusion1 decks3 decks
30%synergy
Night's Whisper
33%inclusion1 decks3 decks
8%synergy
Buried Alive
33%inclusion1 decks3 decks
21%synergy
Hymn to Tourach
33%inclusion1 decks3 decks
31%synergy
Living Death
33%inclusion1 decks3 decks
23%synergy
Reanimate
33%inclusion1 decks3 decks
-7%synergy
Insatiable Avarice
33%inclusion1 decks3 decks
22%synergy
Toxic Deluge
33%inclusion1 decks3 decks
-3%synergy
Damnation
33%inclusion1 decks3 decks
13%synergy
Drown in Ichor
33%inclusion1 decks3 decks
30%synergy
Thoughtseize
33%inclusion1 decks3 decks
29%synergy
Utility Artifacts
Lightning Greaves
100%inclusion3 decks3 decks
66%synergy
Sword of Light and Shadow
67%inclusion2 decks3 decks
66%synergy
Haunted Cloak
67%inclusion2 decks3 decks
66%synergy
Shadowspear
67%inclusion2 decks3 decks
63%synergy
Jet Medallion
67%inclusion2 decks3 decks
4%synergy
Commander's Plate
67%inclusion2 decks3 decks
61%synergy
Sword of Feast and Famine
67%inclusion2 decks3 decks
65%synergy
Blackblade Reforged
67%inclusion2 decks3 decks
64%synergy
Lashwrithe
33%inclusion1 decks3 decks
30%synergy
Quietus Spike
33%inclusion1 decks3 decks
32%synergy
Sensei's Divining Top
33%inclusion1 decks3 decks
25%synergy
Helm of Obedience
33%inclusion1 decks3 decks
33%synergy
Sword of Fire and Ice
33%inclusion1 decks3 decks
33%synergy
Manifold Key
33%inclusion1 decks3 decks
32%synergy
Nightmare Lash
33%inclusion1 decks3 decks
31%synergy
Vorpal Sword
33%inclusion1 decks3 decks
30%synergy
Grafdigger's Cage
33%inclusion1 decks3 decks
33%synergy
Cranial Plating
33%inclusion1 decks3 decks
30%synergy
Transmogrant's Crown
33%inclusion1 decks3 decks
32%synergy
Sword of Truth and Justice
33%inclusion1 decks3 decks
33%synergy
Bloodforged Battle-Axe
33%inclusion1 decks3 decks
33%synergy
Key to the City
33%inclusion1 decks3 decks
31%synergy
Strata Scythe
33%inclusion1 decks3 decks
33%synergy
Inquisitor's Flail
33%inclusion1 decks3 decks
33%synergy
Sword of Hours
33%inclusion1 decks3 decks
33%synergy
Sword of War and Peace
33%inclusion1 decks3 decks
33%synergy
Darksteel Plate
33%inclusion1 decks3 decks
31%synergy
Pact Weapon
33%inclusion1 decks3 decks
31%synergy
Champion's Helm
33%inclusion1 decks3 decks
31%synergy
Mindcrank
33%inclusion1 decks3 decks
28%synergy
Swiftfoot Boots
33%inclusion1 decks3 decks
2%synergy
Batterskull
33%inclusion1 decks3 decks
33%synergy
Ensnaring Bridge
33%inclusion1 decks3 decks
33%synergy
Hammer of Nazahn
33%inclusion1 decks3 decks
33%synergy
Hero's Blade
33%inclusion1 decks3 decks
33%synergy
Trepanation Blade
33%inclusion1 decks3 decks
33%synergy
Enchantments
Unspeakable Symbol
67%inclusion2 decks3 decks
66%synergy
Phyrexian Arena
67%inclusion2 decks3 decks
27%synergy
Wound Reflection
33%inclusion1 decks3 decks
30%synergy
Gate to Phyrexia
33%inclusion1 decks3 decks
33%synergy
Animate Dead
33%inclusion1 decks3 decks
16%synergy
Fungal Fortitude
33%inclusion1 decks3 decks
32%synergy
Black Market Connections
33%inclusion1 decks3 decks
9%synergy
Bloodchief Ascension
33%inclusion1 decks3 decks
24%synergy
Leyline of the Void
33%inclusion1 decks3 decks
32%synergy
Heartless Summoning
33%inclusion1 decks3 decks
28%synergy
Necrogen Communion
33%inclusion1 decks3 decks
32%synergy
Planeswalkers
Liliana of the Dark Realms
67%inclusion2 decks3 decks
53%synergy
Vraska, Betrayal's Sting
33%inclusion1 decks3 decks
31%synergy
Liliana of the Veil
33%inclusion1 decks3 decks
27%synergy
Karn Liberated
33%inclusion1 decks3 decks
33%synergy
Karn, the Great Creator
33%inclusion1 decks3 decks
33%synergy
Utility Lands
Shizo, Death's Storehouse
67%inclusion2 decks3 decks
56%synergy
Maze of Ith
67%inclusion2 decks3 decks
64%synergy
Cathedral of War
67%inclusion2 decks3 decks
66%synergy
Cabal Coffers
67%inclusion2 decks3 decks
12%synergy
Karn's Bastion
67%inclusion2 decks3 decks
63%synergy
Bojuka Bog
33%inclusion1 decks3 decks
-14%synergy
Cabal Stronghold
33%inclusion1 decks3 decks
-1%synergy
Mortuary Mire
33%inclusion1 decks3 decks
20%synergy
Hall of the Bandit Lord
33%inclusion1 decks3 decks
32%synergy
Inkmoth Nexus
33%inclusion1 decks3 decks
32%synergy
Reliquary Tower
33%inclusion1 decks3 decks
3%synergy
Urborg, Tomb of Yawgmoth
33%inclusion1 decks3 decks
-4%synergy
Rogue's Passage
33%inclusion1 decks3 decks
14%synergy
Mana Artifacts
Arcane Signet
67%inclusion2 decks3 decks
5%synergy
Lotus Petal
67%inclusion2 decks3 decks
59%synergy
Sol Ring
67%inclusion2 decks3 decks
-19%synergy
Mox Amber
67%inclusion2 decks3 decks
62%synergy
Staff of Compleation
33%inclusion1 decks3 decks
32%synergy
Glistening Sphere
33%inclusion1 decks3 decks
32%synergy
Throne of Eldraine
33%inclusion1 decks3 decks
24%synergy
Mox Tantalite
33%inclusion1 decks3 decks
33%synergy
Mox Opal
33%inclusion1 decks3 decks
30%synergy
Extraplanar Lens
33%inclusion1 decks3 decks
28%synergy
Lands
Swamp
100%inclusion3 decks3 decks
5%synergy
Cavern of Souls
67%inclusion2 decks3 decks
60%synergy
Fell the Profane
33%inclusion1 decks3 decks
14%synergy
The Seedcore
33%inclusion1 decks3 decks
33%synergy
Plaza of Heroes
33%inclusion1 decks3 decks
32%synergy
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