Skithiryx, the Blight Dragon (Commander) - cEDH Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #790
5decks
As CommanderAs CardAverage DeckDecks
Bracket
All12345
Budget
Any
$
$$$
Background image for The Top 10 Most Played 4-Color Cards in Commander
Nick Price
Dec 17, 2025
Nick Price
The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
Deck Filters
Cardsphere
Archidekt
Commander Spellbook
Moxfield
Scryfall
High Synergy Cards
Game Changers
Creatures
Instants
Sorceries
Utility Artifacts
Enchantments
Planeswalkers
Utility Lands
Mana Artifacts
Lands
Back to Top
Dismember
80%inclusion4 decks5 decks
69%synergy
Lightning Greaves
80%inclusion4 decks5 decks
46%synergy
Dark Ritual
100%inclusion5 decks5 decks
34%synergy
Cabal Coffers
80%inclusion4 decks5 decks
25%synergy
Jet Medallion
80%inclusion4 decks5 decks
20%synergy
Game Changers
Mana Vault
80%inclusion4 decks5 decks
73%synergy
Ancient Tomb
60%inclusion3 decks5 decks
48%synergy
The One Ring
60%inclusion3 decks5 decks
50%synergy
Demonic Tutor
60%inclusion3 decks5 decks
32%synergy
Chrome Mox
60%inclusion3 decks5 decks
54%synergy
Vampiric Tutor
60%inclusion3 decks5 decks
38%synergy
Imperial Seal
40%inclusion2 decks5 decks
33%synergy
Necropotence
40%inclusion2 decks5 decks
25%synergy
Ad Nauseam
40%inclusion2 decks5 decks
37%synergy
Mox Diamond
40%inclusion2 decks5 decks
36%synergy
Creatures
K'rrik, Son of Yawgmoth
60%inclusion3 decks5 decks
41%synergy
Dauthi Voidwalker
60%inclusion3 decks5 decks
44%synergy
Plague Stinger
40%inclusion2 decks5 decks
39%synergy
Whispering Specter
40%inclusion2 decks5 decks
39%synergy
Plague Myr
40%inclusion2 decks5 decks
39%synergy
Crypt Ghast
40%inclusion2 decks5 decks
-8%synergy
Contagious Nim
20%inclusion1 decks5 decks
20%synergy
Nefarox, Overlord of Grixis
20%inclusion1 decks5 decks
20%synergy
Core Prowler
20%inclusion1 decks5 decks
19%synergy
Blackcleave Goblin
20%inclusion1 decks5 decks
20%synergy
Dread Presence
20%inclusion1 decks5 decks
5%synergy
Vector Asp
20%inclusion1 decks5 decks
20%synergy
Pestilent Syphoner
20%inclusion1 decks5 decks
19%synergy
Grim Servant
20%inclusion1 decks5 decks
15%synergy
Silent Arbiter
20%inclusion1 decks5 decks
19%synergy
Erebos, God of the Dead
20%inclusion1 decks5 decks
15%synergy
Opposition Agent
20%inclusion1 decks5 decks
10%synergy
Dark Confidant
20%inclusion1 decks5 decks
13%synergy
Reaper of Sheoldred
20%inclusion1 decks5 decks
19%synergy
Witch-king of Angmar
20%inclusion1 decks5 decks
19%synergy
Necrotic Ooze
20%inclusion1 decks5 decks
15%synergy
Sheoldred, the Apocalypse
20%inclusion1 decks5 decks
5%synergy
Dimir House Guard
20%inclusion1 decks5 decks
16%synergy
Gray Merchant of Asphodel
20%inclusion1 decks5 decks
-32%synergy
Filth
20%inclusion1 decks5 decks
18%synergy
Phyrexian Obliterator
20%inclusion1 decks5 decks
9%synergy
Duty-Bound Dead
20%inclusion1 decks5 decks
20%synergy
Bloodletter of Aclazotz
20%inclusion1 decks5 decks
9%synergy
Pit Scorpion
20%inclusion1 decks5 decks
20%synergy
Nazgûl
20%inclusion1 decks5 decks
19%synergy
Flensermite
20%inclusion1 decks5 decks
19%synergy
Swamp Mosquito
20%inclusion1 decks5 decks
20%synergy
Unstoppable Slasher
20%inclusion1 decks5 decks
14%synergy
Myr Convert
20%inclusion1 decks5 decks
19%synergy
Stinging Hivemaster
20%inclusion1 decks5 decks
20%synergy
Vito, Thorn of the Dusk Rose
20%inclusion1 decks5 decks
9%synergy
Kozilek, Butcher of Truth
20%inclusion1 decks5 decks
19%synergy
Bilious Skulldweller
20%inclusion1 decks5 decks
19%synergy
Ichorclaw Myr
20%inclusion1 decks5 decks
19%synergy
Servant of Nefarox
20%inclusion1 decks5 decks
20%synergy
Corpse Cur
20%inclusion1 decks5 decks
20%synergy
Phyrexian Crusader
20%inclusion1 decks5 decks
19%synergy
Massacre Wurm
20%inclusion1 decks5 decks
3%synergy
Duskmantle Prowler
20%inclusion1 decks5 decks
20%synergy
Archfiend of Despair
20%inclusion1 decks5 decks
17%synergy
Phyrexian Digester
20%inclusion1 decks5 decks
20%synergy
Yawgmoth, Thran Physician
20%inclusion1 decks5 decks
10%synergy
Sheoldred's Headcleaver
20%inclusion1 decks5 decks
20%synergy
Blightbelly Rat
20%inclusion1 decks5 decks
16%synergy
Flesh-Eater Imp
20%inclusion1 decks5 decks
19%synergy
Instants
Deadly Rollick
60%inclusion3 decks5 decks
37%synergy
Whisper of the Dross
60%inclusion3 decks5 decks
57%synergy
Go for the Throat
60%inclusion3 decks5 decks
37%synergy
Snuff Out
60%inclusion3 decks5 decks
47%synergy
Defile
60%inclusion3 decks5 decks
22%synergy
Archenemy's Charm
50%inclusion1 decks2 decks
41%synergy
Astarion's Thirst
40%inclusion2 decks5 decks
38%synergy
Hero's Downfall
40%inclusion2 decks5 decks
33%synergy
Cut Down
40%inclusion2 decks5 decks
36%synergy
Imp's Mischief
40%inclusion2 decks5 decks
16%synergy
Vraska's Fall
40%inclusion2 decks5 decks
36%synergy
Howl from Beyond
40%inclusion2 decks5 decks
39%synergy
Grim Affliction
40%inclusion2 decks5 decks
38%synergy
Cabal Ritual
40%inclusion2 decks5 decks
22%synergy
Bitter Triumph
40%inclusion2 decks5 decks
30%synergy
Tendrils of Corruption
40%inclusion2 decks5 decks
36%synergy
Sudden Spoiling
40%inclusion2 decks5 decks
30%synergy
Tragic Slip
40%inclusion2 decks5 decks
19%synergy
Fell the Profane
20%inclusion1 decks5 decks
1%synergy
Force of Despair
20%inclusion1 decks5 decks
12%synergy
Sheoldred's Edict
20%inclusion1 decks5 decks
6%synergy
Entomb
20%inclusion1 decks5 decks
8%synergy
Consuming Corruption
20%inclusion1 decks5 decks
4%synergy
Hatred
20%inclusion1 decks5 decks
19%synergy
Slaughter Pact
20%inclusion1 decks5 decks
17%synergy
Withering Boon
20%inclusion1 decks5 decks
15%synergy
March of Wretched Sorrow
20%inclusion1 decks5 decks
18%synergy
Darkness
20%inclusion1 decks5 decks
11%synergy
Tainted Strike
20%inclusion1 decks5 decks
17%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-2%synergy
Rain of Filth
20%inclusion1 decks5 decks
17%synergy
Baleful Mastery
20%inclusion1 decks5 decks
11%synergy
Cast Down
20%inclusion1 decks5 decks
18%synergy
Blood Pact
20%inclusion1 decks5 decks
16%synergy
Unmake the Graves
20%inclusion1 decks5 decks
20%synergy
Breathe Your Last
20%inclusion1 decks5 decks
18%synergy
Erebos's Intervention
20%inclusion1 decks5 decks
17%synergy
Withering Torment
20%inclusion1 decks5 decks
-12%synergy
Sorceries
Bubbling Muck
60%inclusion3 decks5 decks
44%synergy
Crux of Fate
60%inclusion3 decks5 decks
59%synergy
Feed the Swarm
60%inclusion3 decks5 decks
9%synergy
Night's Whisper
60%inclusion3 decks5 decks
36%synergy
Sign in Blood
60%inclusion3 decks5 decks
24%synergy
Phyresis Outbreak
40%inclusion2 decks5 decks
38%synergy
Infectious Inquiry
40%inclusion2 decks5 decks
37%synergy
Praetor's Grasp
40%inclusion2 decks5 decks
36%synergy
Insatiable Avarice
40%inclusion2 decks5 decks
28%synergy
Toxic Deluge
40%inclusion2 decks5 decks
3%synergy
Drown in Ichor
40%inclusion2 decks5 decks
36%synergy
Diabolic Intent
20%inclusion1 decks5 decks
6%synergy
Black Sun's Zenith
20%inclusion1 decks5 decks
14%synergy
Diabolic Tutor
20%inclusion1 decks5 decks
5%synergy
Victimize
20%inclusion1 decks5 decks
-6%synergy
Torment of Hailfire
20%inclusion1 decks5 decks
4%synergy
Yawgmoth's Will
20%inclusion1 decks5 decks
17%synergy
Dread Return
20%inclusion1 decks5 decks
8%synergy
Mastermind's Acquisition
20%inclusion1 decks5 decks
18%synergy
Dark Petition
20%inclusion1 decks5 decks
16%synergy
Buried Alive
20%inclusion1 decks5 decks
8%synergy
Living Death
20%inclusion1 decks5 decks
10%synergy
Reanimate
20%inclusion1 decks5 decks
-19%synergy
Damnation
20%inclusion1 decks5 decks
-1%synergy
Grim Tutor
20%inclusion1 decks5 decks
8%synergy
Utility Artifacts
Lashwrithe
60%inclusion3 decks5 decks
56%synergy
Shadowspear
60%inclusion3 decks5 decks
56%synergy
Swiftfoot Boots
60%inclusion3 decks5 decks
28%synergy
Aettir and Priwen
50%inclusion1 decks2 decks
50%synergy
Nightmare Lash
40%inclusion2 decks5 decks
38%synergy
Cranial Plating
40%inclusion2 decks5 decks
36%synergy
Sword of Truth and Justice
40%inclusion2 decks5 decks
39%synergy
Bloodforged Battle-Axe
40%inclusion2 decks5 decks
40%synergy
Strata Scythe
40%inclusion2 decks5 decks
39%synergy
Mindcrank
40%inclusion2 decks5 decks
34%synergy
Commander's Plate
40%inclusion2 decks5 decks
34%synergy
Blackblade Reforged
40%inclusion2 decks5 decks
37%synergy
The Darkness Crystal
33%inclusion1 decks3 decks
14%synergy
Black Mage's Rod
33%inclusion1 decks3 decks
33%synergy
Sword of Light and Shadow
20%inclusion1 decks5 decks
19%synergy
Quietus Spike
20%inclusion1 decks5 decks
19%synergy
Sensei's Divining Top
20%inclusion1 decks5 decks
12%synergy
Helm of Obedience
20%inclusion1 decks5 decks
20%synergy
Umezawa's Jitte
20%inclusion1 decks5 decks
19%synergy
Bolas's Citadel
20%inclusion1 decks5 decks
-9%synergy
Manifold Key
20%inclusion1 decks5 decks
18%synergy
Mithril Coat
20%inclusion1 decks5 decks
14%synergy
Contagion Clasp
20%inclusion1 decks5 decks
17%synergy
Umbral Mantle
20%inclusion1 decks5 decks
19%synergy
Contagion Engine
20%inclusion1 decks5 decks
18%synergy
Leyline Axe
20%inclusion1 decks5 decks
19%synergy
Haunted Cloak
20%inclusion1 decks5 decks
19%synergy
Prosthetic Injector
20%inclusion1 decks5 decks
20%synergy
Inquisitor's Flail
20%inclusion1 decks5 decks
20%synergy
Sword of Hours
20%inclusion1 decks5 decks
20%synergy
Sword of War and Peace
20%inclusion1 decks5 decks
20%synergy
Sword of Wealth and Power
20%inclusion1 decks5 decks
19%synergy
Darksteel Plate
20%inclusion1 decks5 decks
18%synergy
Sword of Feast and Famine
20%inclusion1 decks5 decks
18%synergy
Ensnaring Bridge
20%inclusion1 decks5 decks
19%synergy
Isochron Scepter
20%inclusion1 decks5 decks
20%synergy
Hammer of Nazahn
20%inclusion1 decks5 decks
19%synergy
Hero's Blade
20%inclusion1 decks5 decks
20%synergy
Trepanation Blade
20%inclusion1 decks5 decks
20%synergy
Grafted Exoskeleton
20%inclusion1 decks5 decks
19%synergy
Enchantments
Unspeakable Symbol
60%inclusion3 decks5 decks
59%synergy
Black Market Connections
60%inclusion3 decks5 decks
37%synergy
Phyrexian Arena
60%inclusion3 decks5 decks
20%synergy
Bloodchief Ascension
40%inclusion2 decks5 decks
30%synergy
Shade's Form
20%inclusion1 decks5 decks
19%synergy
Wound Reflection
20%inclusion1 decks5 decks
16%synergy
Snake Cult Initiation
20%inclusion1 decks5 decks
20%synergy
Gate to Phyrexia
20%inclusion1 decks5 decks
19%synergy
Animate Dead
20%inclusion1 decks5 decks
2%synergy
Oubliette
20%inclusion1 decks5 decks
17%synergy
Endless Scream
20%inclusion1 decks5 decks
20%synergy
Fungal Fortitude
20%inclusion1 decks5 decks
19%synergy
Leyline of the Void
20%inclusion1 decks5 decks
18%synergy
Heartless Summoning
20%inclusion1 decks5 decks
15%synergy
Necrogen Communion
20%inclusion1 decks5 decks
18%synergy
Planeswalkers
Liliana of the Dark Realms
60%inclusion3 decks5 decks
46%synergy
Vraska, Betrayal's Sting
40%inclusion2 decks5 decks
37%synergy
Karn, the Great Creator
20%inclusion1 decks5 decks
19%synergy
Utility Lands
Shizo, Death's Storehouse
60%inclusion3 decks5 decks
50%synergy
Karn's Bastion
60%inclusion3 decks5 decks
56%synergy
Urborg, Tomb of Yawgmoth
60%inclusion3 decks5 decks
22%synergy
Cabal Stronghold
40%inclusion2 decks5 decks
4%synergy
Cathedral of War
40%inclusion2 decks5 decks
40%synergy
Inkmoth Nexus
40%inclusion2 decks5 decks
39%synergy
Rogue's Passage
40%inclusion2 decks5 decks
22%synergy
Bojuka Bog
20%inclusion1 decks5 decks
-27%synergy
Witch's Clinic
20%inclusion1 decks5 decks
19%synergy
Vault of Whispers
20%inclusion1 decks5 decks
14%synergy
Mortuary Mire
20%inclusion1 decks5 decks
7%synergy
Maze of Ith
20%inclusion1 decks5 decks
17%synergy
The Black Gate
20%inclusion1 decks5 decks
17%synergy
Urza's Saga
20%inclusion1 decks5 decks
12%synergy
The Tabernacle at Pendrell Vale
20%inclusion1 decks5 decks
20%synergy
Spymaster's Vault
20%inclusion1 decks5 decks
10%synergy
Glacial Chasm
20%inclusion1 decks5 decks
19%synergy
Forge of Heroes
20%inclusion1 decks5 decks
20%synergy
Geier Reach Sanitarium
20%inclusion1 decks5 decks
8%synergy
Minas Morgul, Dark Fortress
20%inclusion1 decks5 decks
17%synergy
Mikokoro, Center of the Sea
20%inclusion1 decks5 decks
17%synergy
Takenuma, Abandoned Mire
20%inclusion1 decks5 decks
4%synergy
Lake of the Dead
20%inclusion1 decks5 decks
15%synergy
Reliquary Tower
20%inclusion1 decks5 decks
-11%synergy
Temple of the False God
20%inclusion1 decks5 decks
12%synergy
Strip Mine
20%inclusion1 decks5 decks
17%synergy
Mana Artifacts
Sol Ring
100%inclusion5 decks5 decks
14%synergy
Arcane Signet
60%inclusion3 decks5 decks
-2%synergy
Staff of Compleation
60%inclusion3 decks5 decks
58%synergy
Lotus Petal
60%inclusion3 decks5 decks
53%synergy
Mox Opal
60%inclusion3 decks5 decks
57%synergy
The Soul Stone
50%inclusion1 decks2 decks
37%synergy
Glistening Sphere
40%inclusion2 decks5 decks
39%synergy
Throne of Eldraine
20%inclusion1 decks5 decks
9%synergy
Mox Amber
20%inclusion1 decks5 decks
16%synergy
Sol Talisman
20%inclusion1 decks5 decks
19%synergy
Mox Tantalite
20%inclusion1 decks5 decks
20%synergy
Sceptre of Eternal Glory
20%inclusion1 decks5 decks
11%synergy
Lands
Swamp
100%inclusion5 decks5 decks
5%synergy
Cavern of Souls
60%inclusion3 decks5 decks
53%synergy
Fell the Profane
20%inclusion1 decks5 decks
1%synergy
Plaza of Heroes
20%inclusion1 decks5 decks
19%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-2%synergy
Gemstone Caverns
20%inclusion1 decks5 decks
16%synergy
About UsContactPrivacy PolicyTerms of Service
Space Cow MediaArchidektCardsphereCommander SpellbookFABRECSpellvoid
Space Cow MediaArchidektCommander's Herald
Commander SpellbookFABRECSpellvoid
EDHREC is unofficial Fan Content permitted under the Fan Content Policy. Not approved/endorsed by Wizards. Portions of the materials used are property of Wizards of the Coast. ©Wizards of the Coast LLC.
next@15 test