Skithiryx, the Blight Dragon (Commander) - cEDH Infect

Alternate Names:

Venom, King in BlackVenom, King in Black

Skithiryx, the Blight Dragon
Rank #795
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Dec 17, 2025
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The Top 10 Most Played 4-Color Cards in Commander
Which 4-color cards are the most played in Commander? Unsurprisingly, the list is full of powerful, and popular, legendary creatures.
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Utility Lands
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Lands
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Unspeakable Symbol
80%inclusion4 decks5 decks
79%synergy
Crux of Fate
80%inclusion4 decks5 decks
79%synergy
Shadowspear
80%inclusion4 decks5 decks
76%synergy
Shizo, Death's Storehouse
80%inclusion4 decks5 decks
70%synergy
Dismember
80%inclusion4 decks5 decks
70%synergy
Liliana of the Dark Realms
80%inclusion4 decks5 decks
66%synergy
Go for the Throat
80%inclusion4 decks5 decks
57%synergy
Lightning Greaves
80%inclusion4 decks5 decks
46%synergy
Dark Ritual
100%inclusion5 decks5 decks
33%synergy
Feed the Swarm
80%inclusion4 decks5 decks
30%synergy
Top Cards
Jet Medallion
80%inclusion4 decks5 decks
18%synergy
Game Changers
Ancient Tomb
80%inclusion4 decks5 decks
68%synergy
Mana Vault
80%inclusion4 decks5 decks
73%synergy
Demonic Tutor
80%inclusion4 decks5 decks
53%synergy
Chrome Mox
80%inclusion4 decks5 decks
74%synergy
The One Ring
60%inclusion3 decks5 decks
51%synergy
Vampiric Tutor
60%inclusion3 decks5 decks
39%synergy
Imperial Seal
40%inclusion2 decks5 decks
33%synergy
Bolas's Citadel
40%inclusion2 decks5 decks
11%synergy
Necropotence
40%inclusion2 decks5 decks
25%synergy
Ad Nauseam
40%inclusion2 decks5 decks
37%synergy
Creatures
K'rrik, Son of Yawgmoth
60%inclusion3 decks5 decks
41%synergy
Dauthi Voidwalker
60%inclusion3 decks5 decks
44%synergy
Plague Stinger
40%inclusion2 decks5 decks
39%synergy
Crypt Ghast
40%inclusion2 decks5 decks
-8%synergy
Nefarox, Overlord of Grixis
20%inclusion1 decks5 decks
20%synergy
Whispering Specter
20%inclusion1 decks5 decks
19%synergy
Pestilent Syphoner
20%inclusion1 decks5 decks
19%synergy
Grim Servant
20%inclusion1 decks5 decks
15%synergy
Silent Arbiter
20%inclusion1 decks5 decks
19%synergy
Erebos, God of the Dead
20%inclusion1 decks5 decks
15%synergy
Opposition Agent
20%inclusion1 decks5 decks
10%synergy
Dark Confidant
20%inclusion1 decks5 decks
12%synergy
Witch-king of Angmar
20%inclusion1 decks5 decks
19%synergy
Plague Myr
20%inclusion1 decks5 decks
19%synergy
Necrotic Ooze
20%inclusion1 decks5 decks
16%synergy
Sheoldred, the Apocalypse
20%inclusion1 decks5 decks
5%synergy
Dimir House Guard
20%inclusion1 decks5 decks
17%synergy
Gray Merchant of Asphodel
20%inclusion1 decks5 decks
-31%synergy
Phyrexian Obliterator
20%inclusion1 decks5 decks
9%synergy
Duty-Bound Dead
20%inclusion1 decks5 decks
20%synergy
Bloodletter of Aclazotz
20%inclusion1 decks5 decks
10%synergy
Nazgûl
20%inclusion1 decks5 decks
19%synergy
Unstoppable Slasher
20%inclusion1 decks5 decks
14%synergy
Myr Convert
20%inclusion1 decks5 decks
19%synergy
Vito, Thorn of the Dusk Rose
20%inclusion1 decks5 decks
9%synergy
Kozilek, Butcher of Truth
20%inclusion1 decks5 decks
19%synergy
Bilious Skulldweller
20%inclusion1 decks5 decks
19%synergy
Servant of Nefarox
20%inclusion1 decks5 decks
20%synergy
Phyrexian Crusader
20%inclusion1 decks5 decks
19%synergy
Massacre Wurm
20%inclusion1 decks5 decks
3%synergy
Duskmantle Prowler
20%inclusion1 decks5 decks
20%synergy
Archfiend of Despair
20%inclusion1 decks5 decks
17%synergy
Chainer, Dementia Master
20%inclusion1 decks5 decks
15%synergy
Plague Engineer
20%inclusion1 decks5 decks
20%synergy
Knight of Infamy
20%inclusion1 decks5 decks
20%synergy
Orcish Bowmasters
20%inclusion1 decks5 decks
7%synergy
Viscera Seer
20%inclusion1 decks5 decks
3%synergy
Bloodthirsty Conqueror
20%inclusion1 decks5 decks
11%synergy
Instants
Deadly Rollick
60%inclusion3 decks5 decks
35%synergy
Snuff Out
60%inclusion3 decks5 decks
47%synergy
Cabal Ritual
60%inclusion3 decks5 decks
42%synergy
Archenemy's Charm
50%inclusion1 decks2 decks
41%synergy
Astarion's Thirst
40%inclusion2 decks5 decks
39%synergy
Hero's Downfall
40%inclusion2 decks5 decks
33%synergy
Cut Down
40%inclusion2 decks5 decks
36%synergy
Whisper of the Dross
40%inclusion2 decks5 decks
37%synergy
Imp's Mischief
40%inclusion2 decks5 decks
15%synergy
Howl from Beyond
40%inclusion2 decks5 decks
39%synergy
Hatred
40%inclusion2 decks5 decks
39%synergy
Defile
40%inclusion2 decks5 decks
4%synergy
Slaughter Pact
40%inclusion2 decks5 decks
38%synergy
Bitter Triumph
40%inclusion2 decks5 decks
30%synergy
Tendrils of Corruption
40%inclusion2 decks5 decks
36%synergy
Sudden Spoiling
40%inclusion2 decks5 decks
31%synergy
Fell the Profane
20%inclusion1 decks5 decks
1%synergy
Force of Despair
20%inclusion1 decks5 decks
12%synergy
Sheoldred's Edict
20%inclusion1 decks5 decks
5%synergy
Entomb
20%inclusion1 decks5 decks
8%synergy
Vraska's Fall
20%inclusion1 decks5 decks
17%synergy
Consuming Corruption
20%inclusion1 decks5 decks
4%synergy
Anoint with Affliction
20%inclusion1 decks5 decks
19%synergy
Grim Affliction
20%inclusion1 decks5 decks
18%synergy
Doom Blade
20%inclusion1 decks5 decks
13%synergy
Unnatural Endurance
20%inclusion1 decks5 decks
20%synergy
Withering Boon
20%inclusion1 decks5 decks
16%synergy
March of Wretched Sorrow
20%inclusion1 decks5 decks
19%synergy
Virulent Swipe
20%inclusion1 decks5 decks
20%synergy
Funeral Charm
20%inclusion1 decks5 decks
19%synergy
Darkness
20%inclusion1 decks5 decks
10%synergy
Tainted Strike
20%inclusion1 decks5 decks
17%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-3%synergy
Rain of Filth
20%inclusion1 decks5 decks
17%synergy
Baleful Mastery
20%inclusion1 decks5 decks
12%synergy
Blood Pact
20%inclusion1 decks5 decks
16%synergy
Unmake the Graves
20%inclusion1 decks5 decks
20%synergy
Erebos's Intervention
20%inclusion1 decks5 decks
18%synergy
Tragic Slip
20%inclusion1 decks5 decks
0%synergy
Withering Torment
20%inclusion1 decks5 decks
-11%synergy
Sorceries
Bubbling Muck
60%inclusion3 decks5 decks
44%synergy
Sign in Blood
60%inclusion3 decks5 decks
25%synergy
Phyresis Outbreak
40%inclusion2 decks5 decks
38%synergy
Infectious Inquiry
40%inclusion2 decks5 decks
37%synergy
Praetor's Grasp
40%inclusion2 decks5 decks
36%synergy
Night's Whisper
40%inclusion2 decks5 decks
15%synergy
Insatiable Avarice
40%inclusion2 decks5 decks
29%synergy
Toxic Deluge
40%inclusion2 decks5 decks
3%synergy
Damnation
40%inclusion2 decks5 decks
20%synergy
Diabolic Intent
20%inclusion1 decks5 decks
5%synergy
Black Sun's Zenith
20%inclusion1 decks5 decks
15%synergy
Diabolic Tutor
20%inclusion1 decks5 decks
6%synergy
Mandate of Abaddon
20%inclusion1 decks5 decks
19%synergy
Victimize
20%inclusion1 decks5 decks
-7%synergy
Profane Tutor
20%inclusion1 decks5 decks
16%synergy
Torment of Hailfire
20%inclusion1 decks5 decks
5%synergy
Yawgmoth's Will
20%inclusion1 decks5 decks
17%synergy
Dread Return
20%inclusion1 decks5 decks
8%synergy
Inquisition of Kozilek
20%inclusion1 decks5 decks
18%synergy
Mastermind's Acquisition
20%inclusion1 decks5 decks
18%synergy
Chainer's Edict
20%inclusion1 decks5 decks
19%synergy
Dark Petition
20%inclusion1 decks5 decks
16%synergy
Buried Alive
20%inclusion1 decks5 decks
8%synergy
Hymn to Tourach
20%inclusion1 decks5 decks
18%synergy
Living Death
20%inclusion1 decks5 decks
10%synergy
Reanimate
20%inclusion1 decks5 decks
-20%synergy
Drown in Ichor
20%inclusion1 decks5 decks
16%synergy
Grim Tutor
20%inclusion1 decks5 decks
8%synergy
Thoughtseize
20%inclusion1 decks5 decks
15%synergy
Utility Artifacts
Lashwrithe
60%inclusion3 decks5 decks
56%synergy
Commander's Plate
60%inclusion3 decks5 decks
54%synergy
Blackblade Reforged
60%inclusion3 decks5 decks
57%synergy
Aettir and Priwen
50%inclusion1 decks2 decks
50%synergy
Sword of Light and Shadow
40%inclusion2 decks5 decks
39%synergy
Nightmare Lash
40%inclusion2 decks5 decks
38%synergy
Haunted Cloak
40%inclusion2 decks5 decks
39%synergy
Cranial Plating
40%inclusion2 decks5 decks
37%synergy
Sword of Truth and Justice
40%inclusion2 decks5 decks
39%synergy
Bloodforged Battle-Axe
40%inclusion2 decks5 decks
40%synergy
Strata Scythe
40%inclusion2 decks5 decks
39%synergy
Mindcrank
40%inclusion2 decks5 decks
35%synergy
Swiftfoot Boots
40%inclusion2 decks5 decks
9%synergy
Sword of Feast and Famine
40%inclusion2 decks5 decks
38%synergy
Hero's Blade
40%inclusion2 decks5 decks
40%synergy
The Darkness Crystal
33%inclusion1 decks3 decks
13%synergy
Black Mage's Rod
33%inclusion1 decks3 decks
33%synergy
Quietus Spike
20%inclusion1 decks5 decks
19%synergy
Sensei's Divining Top
20%inclusion1 decks5 decks
12%synergy
Helm of Obedience
20%inclusion1 decks5 decks
20%synergy
Umezawa's Jitte
20%inclusion1 decks5 decks
20%synergy
Sword of Fire and Ice
20%inclusion1 decks5 decks
20%synergy
Manifold Key
20%inclusion1 decks5 decks
18%synergy
Mithril Coat
20%inclusion1 decks5 decks
14%synergy
Umbral Mantle
20%inclusion1 decks5 decks
19%synergy
Leyline Axe
20%inclusion1 decks5 decks
19%synergy
Vorpal Sword
20%inclusion1 decks5 decks
16%synergy
Grafdigger's Cage
20%inclusion1 decks5 decks
20%synergy
Transmogrant's Crown
20%inclusion1 decks5 decks
19%synergy
Key to the City
20%inclusion1 decks5 decks
18%synergy
Inquisitor's Flail
20%inclusion1 decks5 decks
20%synergy
Sword of Hours
20%inclusion1 decks5 decks
20%synergy
Sword of War and Peace
20%inclusion1 decks5 decks
20%synergy
Sword of Wealth and Power
20%inclusion1 decks5 decks
19%synergy
Darksteel Plate
20%inclusion1 decks5 decks
18%synergy
Pact Weapon
20%inclusion1 decks5 decks
18%synergy
Champion's Helm
20%inclusion1 decks5 decks
18%synergy
Batterskull
20%inclusion1 decks5 decks
20%synergy
Ensnaring Bridge
20%inclusion1 decks5 decks
19%synergy
Isochron Scepter
20%inclusion1 decks5 decks
20%synergy
Hammer of Nazahn
20%inclusion1 decks5 decks
19%synergy
Trepanation Blade
20%inclusion1 decks5 decks
20%synergy
Enchantments
Black Market Connections
60%inclusion3 decks5 decks
36%synergy
Phyrexian Arena
60%inclusion3 decks5 decks
20%synergy
Bloodchief Ascension
40%inclusion2 decks5 decks
31%synergy
Shade's Form
20%inclusion1 decks5 decks
19%synergy
Wound Reflection
20%inclusion1 decks5 decks
17%synergy
Gate to Phyrexia
20%inclusion1 decks5 decks
19%synergy
Animate Dead
20%inclusion1 decks5 decks
3%synergy
Oubliette
20%inclusion1 decks5 decks
17%synergy
Endless Scream
20%inclusion1 decks5 decks
20%synergy
Fungal Fortitude
20%inclusion1 decks5 decks
19%synergy
Leyline of the Void
20%inclusion1 decks5 decks
18%synergy
Heartless Summoning
20%inclusion1 decks5 decks
15%synergy
Necrogen Communion
20%inclusion1 decks5 decks
18%synergy
Planeswalkers
Vraska, Betrayal's Sting
40%inclusion2 decks5 decks
37%synergy
Liliana of the Veil
20%inclusion1 decks5 decks
13%synergy
Karn Liberated
20%inclusion1 decks5 decks
20%synergy
Karn, the Great Creator
20%inclusion1 decks5 decks
19%synergy
Utility Lands
Cabal Coffers
80%inclusion4 decks5 decks
25%synergy
Cathedral of War
60%inclusion3 decks5 decks
60%synergy
Karn's Bastion
60%inclusion3 decks5 decks
56%synergy
Cabal Stronghold
40%inclusion2 decks5 decks
5%synergy
Maze of Ith
40%inclusion2 decks5 decks
37%synergy
Inkmoth Nexus
40%inclusion2 decks5 decks
39%synergy
Urborg, Tomb of Yawgmoth
40%inclusion2 decks5 decks
2%synergy
Rogue's Passage
40%inclusion2 decks5 decks
21%synergy
Bojuka Bog
20%inclusion1 decks5 decks
-27%synergy
Witch's Clinic
20%inclusion1 decks5 decks
19%synergy
Vault of Whispers
20%inclusion1 decks5 decks
15%synergy
Mortuary Mire
20%inclusion1 decks5 decks
7%synergy
Hall of the Bandit Lord
20%inclusion1 decks5 decks
19%synergy
The Black Gate
20%inclusion1 decks5 decks
17%synergy
Urza's Saga
20%inclusion1 decks5 decks
12%synergy
The Tabernacle at Pendrell Vale
20%inclusion1 decks5 decks
20%synergy
Spymaster's Vault
20%inclusion1 decks5 decks
10%synergy
Glacial Chasm
20%inclusion1 decks5 decks
19%synergy
Forge of Heroes
20%inclusion1 decks5 decks
20%synergy
Geier Reach Sanitarium
20%inclusion1 decks5 decks
9%synergy
Minas Morgul, Dark Fortress
20%inclusion1 decks5 decks
17%synergy
Mikokoro, Center of the Sea
20%inclusion1 decks5 decks
18%synergy
Takenuma, Abandoned Mire
20%inclusion1 decks5 decks
4%synergy
Lake of the Dead
20%inclusion1 decks5 decks
15%synergy
Reliquary Tower
20%inclusion1 decks5 decks
-10%synergy
Temple of the False God
20%inclusion1 decks5 decks
12%synergy
Strip Mine
20%inclusion1 decks5 decks
17%synergy
Mana Artifacts
Arcane Signet
80%inclusion4 decks5 decks
18%synergy
Sol Ring
80%inclusion4 decks5 decks
-6%synergy
Lotus Petal
60%inclusion3 decks5 decks
53%synergy
Mox Opal
60%inclusion3 decks5 decks
57%synergy
The Soul Stone
50%inclusion1 decks2 decks
35%synergy
Staff of Compleation
40%inclusion2 decks5 decks
38%synergy
Mox Amber
40%inclusion2 decks5 decks
36%synergy
Mox Diamond
40%inclusion2 decks5 decks
36%synergy
Glistening Sphere
20%inclusion1 decks5 decks
19%synergy
Throne of Eldraine
20%inclusion1 decks5 decks
10%synergy
Sol Talisman
20%inclusion1 decks5 decks
20%synergy
Mox Tantalite
20%inclusion1 decks5 decks
20%synergy
Extraplanar Lens
20%inclusion1 decks5 decks
15%synergy
Lands
Swamp
100%inclusion5 decks5 decks
5%synergy
Cavern of Souls
80%inclusion4 decks5 decks
73%synergy
Fell the Profane
20%inclusion1 decks5 decks
1%synergy
The Seedcore
20%inclusion1 decks5 decks
20%synergy
Plaza of Heroes
20%inclusion1 decks5 decks
19%synergy
Malakir Rebirth
20%inclusion1 decks5 decks
-3%synergy
Gemstone Caverns
20%inclusion1 decks5 decks
16%synergy
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